Malin Parmar - Publications

Lund University, Lund, Skåne län, Sweden 
neuroscience, Parkinson's disease, cell therapy

122 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Schellino R, Besusso D, Parolisi R, Gómez-González GB, Dallere S, Scaramuzza L, Ribodino M, Campus I, Conforti P, Parmar M, Boido M, Cattaneo E, Buffo A. hESC-derived striatal progenitors grafted into a Huntington's disease rat model support long-term functional motor recovery by differentiating, self-organizing and connecting into the lesioned striatum. Stem Cell Research & Therapy. 14: 189. PMID 37507794 DOI: 10.1186/s13287-023-03422-4  0.469
2023 Rájová J, Davidsson M, Avallone M, Hartnor M, Aldrin-Kirk P, Cardoso T, Nolbrant S, Mollbrink A, Storm P, Heuer A, Parmar M, Björklund T. Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants . Molecular Therapy. Methods & Clinical Development. 29: 381-394. PMID 37251982 DOI: 10.1016/j.omtm.2023.04.008  0.483
2022 Sozzi E, Kajtez J, Bruzelius A, Wesseler MF, Nilsson F, Birtele M, Larsen NB, Ottosson DR, Storm P, Parmar M, Fiorenzano A. Silk scaffolding drives self-assembly of functional and mature human brain organoids. Frontiers in Cell and Developmental Biology. 10: 1023279. PMID 36313550 DOI: 10.3389/fcell.2022.1023279  0.338
2022 Birtele M, Storm P, Sharma Y, Kajtez J, Wahlestedt JN, Sozzi E, Nilsson F, Stott S, He XL, Mattsson B, Ottosson DR, Barker RA, Fiorenzano A, Parmar M. Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain. Development (Cambridge, England). PMID 36305490 DOI: 10.1242/dev.200504  0.547
2022 Drouin-Ouellet J, Legault EM, Nilsson F, Pircs K, Bouquety J, Petit F, Shrigley S, Birtele M, Pereira M, Storm P, Sharma Y, Bruzelius A, Vuono R, Kele M, Stoker TB, ... ... Parmar M, et al. Age-related pathological impairments in directly reprogrammed dopaminergic neurons derived from patients with idiopathic Parkinson's disease. Stem Cell Reports. PMID 36150382 DOI: 10.1016/j.stemcr.2022.08.010  0.678
2022 Sozzi E, Nilsson F, Kajtez J, Parmar M, Fiorenzano A. Generation of Human Ventral Midbrain Organoids Derived from Pluripotent Stem Cells. Current Protocols. 2: e555. PMID 36121202 DOI: 10.1002/cpz1.555  0.559
2022 Kajtez J, Wesseler MF, Birtele M, Khorasgani FR, Rylander Ottosson D, Heiskanen A, Kamperman T, Leijten J, Martínez-Serrano A, Larsen NB, Angelini TE, Parmar M, Lind JU, Emnéus J. Embedded 3D Printing in Self-Healing Annealable Composites for Precise Patterning of Functionally Mature Human Neural Constructs. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2201392. PMID 35712780 DOI: 10.1002/advs.202201392  0.345
2022 Fiorenzano A, Sozzi E, Birtele M, Kajtez J, Giacomoni J, Nilsson F, Bruzelius A, Sharma Y, Zhang Y, Mattsson B, Emnéus J, Ottosson DR, Storm P, Parmar M. Author Correction: Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids. Nature Communications. 13: 3312. PMID 35676291 DOI: 10.1038/s41467-022-31024-w  0.443
2022 Alekseenko Z, Dias JM, Adler AF, Kozhevnikova M, van Lunteren JA, Nolbrant S, Jeggari A, Vasylovska S, Yoshitake T, Kehr J, Carlén M, Alexeyenko A, Parmar M, Ericson J. Robust derivation of transplantable dopamine neurons from human pluripotent stem cells by timed retinoic acid delivery. Nature Communications. 13: 3046. PMID 35650213 DOI: 10.1038/s41467-022-30777-8  0.53
2022 Elabi OF, Pass R, Sormonta I, Nolbrant S, Drummond N, Kirkeby A, Kunath T, Parmar M, Lane EL. Human Embryonic Stem Cell-Derived Dopaminergic Grafts Alleviate L-DOPA Induced Dyskinesia. Journal of Parkinson's Disease. PMID 35466951 DOI: 10.3233/JPD-212920  0.85
2021 Aldrin-Kirk P, Åkerblom M, Cardoso T, Nolbrant S, Adler AF, Liu X, Heuer A, Davidsson M, Parmar M, Björklund T. A novel two-factor monosynaptic TRIO tracing method for assessment of circuit integration of hESC-derived dopamine transplants. Stem Cell Reports. PMID 34971563 DOI: 10.1016/j.stemcr.2021.11.014  0.464
2021 Pircs K, Drouin-Ouellet J, Horváth V, Gil J, Rezeli M, Garza R, Grassi DA, Sharma Y, St-Amour I, Harris K, Jönsson ME, Johansson PA, Vuono R, Fazal SV, Stoker T, ... ... Parmar M, et al. Distinct subcellular autophagy impairments in induced neurons from Huntington's disease patients. Brain : a Journal of Neurology. PMID 34936701 DOI: 10.1093/brain/awab473  0.824
2021 Fiorenzano A, Sozzi E, Birtele M, Kajtez J, Giacomoni J, Nilsson F, Bruzelius A, Sharma Y, Zhang Y, Mattsson B, Emnéus J, Ottosson DR, Storm P, Parmar M. Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids. Nature Communications. 12: 7302. PMID 34911939 DOI: 10.1038/s41467-021-27464-5  0.487
2021 Johansson PA, Brattås PL, Douse CH, Hsieh P, Adami A, Pontis J, Grassi D, Garza R, Sozzi E, Cataldo R, Jönsson ME, Atacho DAM, Pircs K, Eren F, Sharma Y, ... ... Parmar M, et al. A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development. Cell Stem Cell. PMID 34624206 DOI: 10.1016/j.stem.2021.09.008  0.799
2021 Fiorenzano A, Sozzi E, Parmar M, Storm P. Dopamine Neuron Diversity: Recent Advances and Current Challenges in Human Stem Cell Models and Single Cell Sequencing. Cells. 10. PMID 34206038 DOI: 10.3390/cells10061366  0.542
2021 Fiorenzano A, Sozzi E, Parmar M, Storm P. Dopamine Neuron Diversity: Recent Advances and Current Challenges in Human Stem Cell Models and Single Cell Sequencing. Cells. 10. PMID 34206038 DOI: 10.3390/cells10061366  0.542
2021 Parmar M, Björklund A, Björklund T. In vivo conversion of dopamine neurons in mouse models of Parkinson's disease - a future approach for regenerative therapy? Current Opinion in Genetics & Development. 70: 76-82. PMID 34175529 DOI: 10.1016/j.gde.2021.06.002  0.48
2021 Brambach M, Ernst A, Nolbrant S, Drouin-Ouellet J, Kirkeby A, Parmar M, Olariu V. Neural tube patterning: from a minimal model for rostrocaudal patterning toward an integrated 3D model. Iscience. 24: 102559. PMID 34142058 DOI: 10.1016/j.isci.2021.102559  0.7
2021 Kajtez J, Nilsson F, Fiorenzano A, Parmar M, Emnéus J. 3D biomaterial models of human brain disease. Neurochemistry International. 105043. PMID 33887378 DOI: 10.1016/j.neuint.2021.105043  0.355
2021 Björklund A, Parmar M. Dopamine Cell Therapy: From Cell Replacement to Circuitry Repair. Journal of Parkinson's Disease. PMID 33814467 DOI: 10.3233/JPD-212609  0.498
2021 Fiorenzano A, Birtele M, Wahlestedt JN, Parmar M. Evaluation of -Cre knock-in cell lines for detection and specific targeting of stem cell-derived dopaminergic neurons. Heliyon. 7: e06006. PMID 33532642 DOI: 10.1016/j.heliyon.2021.e06006  0.567
2021 Nilsson F, Storm P, Sozzi E, Hidalgo Gil D, Birtele M, Sharma Y, Parmar M, Fiorenzano A. Single-Cell Profiling of Coding and Noncoding Genes in Human Dopamine Neuron Differentiation. Cells. 10. PMID 33445654 DOI: 10.3390/cells10010137  0.562
2020 Shrigley S, Nilsson F, Mattsson B, Fiorenzano A, Mudannayake J, Bruzelius A, Ottosson DR, Björklund A, Hoban DB, Parmar M. Grafts Derived from an α-Synuclein Triplication Patient Mediate Functional Recovery but Develop Disease-Associated Pathology in the 6-OHDA Model of Parkinson's Disease. Journal of Parkinson's Disease. PMID 33361611 DOI: 10.3233/JPD-202366  0.426
2020 Nolbrant S, Giacomoni J, Hoban DB, Bruzelius A, Birtele M, Chandler-Militello D, Pereira M, Ottosson DR, Goldman SA, Parmar M. Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons. Stem Cell Reports. PMID 32976765 DOI: 10.1016/j.stemcr.2020.08.013  0.587
2020 Kajtez J, Buchmann S, Vasudevan S, Birtele M, Rocchetti S, Pless CJ, Heiskanen A, Barker RA, Martínez-Serrano A, Parmar M, Lind JU, Emnéus J. 3D-Printed Soft Lithography for Complex Compartmentalized Microfluidic Neural Devices. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 2001150. PMID 32832365 DOI: 10.1002/Advs.202001150  0.355
2020 Tiklová K, Nolbrant S, Fiorenzano A, Björklund ÅK, Sharma Y, Heuer A, Gillberg L, Hoban DB, Cardoso T, Adler AF, Birtele M, Lundén-Miguel H, Volakakis N, Kirkeby A, Perlmann T, ... Parmar M, et al. Author Correction: Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease. Nature Communications. 11: 3630. PMID 32669619 DOI: 10.1038/S41467-020-17421-Z  0.761
2020 Parmar M, Björklund A. From Skin to Brain: A Parkinson's Disease Patient Transplanted with His Own Cells. Cell Stem Cell. 27: 8-10. PMID 32619520 DOI: 10.1016/J.Stem.2020.06.008  0.525
2020 Björklund A, Parmar M. Neuronal Replacement as a Tool for Basal Ganglia Circuitry Repair: 40 Years in Perspective. Frontiers in Cellular Neuroscience. 14: 146. PMID 32547369 DOI: 10.3389/Fncel.2020.00146  0.524
2020 Hoban DB, Shrigley S, Mattsson B, Breger LS, Jarl U, Cardoso T, Nelander Wahlestedt J, Luk KC, Björklund A, Parmar M. Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD. Proceedings of the National Academy of Sciences of the United States of America. PMID 32541058 DOI: 10.1073/Pnas.2001305117  0.816
2020 Rifes P, Isaksson M, Rathore GS, Aldrin-Kirk P, Møller OK, Barzaghi G, Lee J, Egerod KL, Rausch DM, Parmar M, Pers TH, Laurell T, Kirkeby A. Publisher Correction: Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient. Nature Biotechnology. PMID 32528133 DOI: 10.1038/S41587-020-0590-4  0.761
2020 Rifes P, Isaksson M, Rathore GS, Aldrin-Kirk P, Møller OK, Barzaghi G, Lee J, Egerod KL, Rausch DM, Parmar M, Pers TH, Laurell T, Kirkeby A. Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient. Nature Biotechnology. PMID 32451506 DOI: 10.1038/S41587-020-0525-0  0.776
2020 Tiklová K, Nolbrant S, Fiorenzano A, Björklund ÅK, Sharma Y, Heuer A, Gillberg L, Hoban DB, Cardoso T, Adler AF, Birtele M, Lundén-Miguel H, Volakakis N, Kirkeby A, Perlmann T, ... Parmar M, et al. Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease. Nature Communications. 11: 2434. PMID 32415072 DOI: 10.1038/S41467-020-16225-5  0.812
2020 Besusso D, Schellino R, Boido M, Belloli S, Parolisi R, Conforti P, Faedo A, Cernigoj M, Campus I, Laporta A, Bocchi VD, Murtaj V, Parmar M, Spaiardi P, Talpo F, et al. Stem Cell-Derived Human Striatal Progenitors Innervate Striatal Targets and Alleviate Sensorimotor Deficit in a Rat Model of Huntington Disease. Stem Cell Reports. PMID 32302555 DOI: 10.1016/J.Stemcr.2020.03.018  0.564
2020 Palma-Tortosa S, Tornero D, Grønning Hansen M, Monni E, Hajy M, Kartsivadze S, Aktay S, Tsupykov O, Parmar M, Deisseroth K, Skibo G, Lindvall O, Kokaia Z. Activity in grafted human iPS cell-derived cortical neurons integrated in stroke-injured rat brain regulates motor behavior. Proceedings of the National Academy of Sciences of the United States of America. PMID 32253308 DOI: 10.1073/Pnas.2000690117  0.67
2020 Adler AF, Björklund A, Parmar M. Transsynaptic tracing and its emerging use to assess graft-reconstructed neural circuits. Stem Cells (Dayton, Ohio). PMID 32101353 DOI: 10.1002/Stem.3166  0.548
2020 Grassi DA, Brattås PL, Jönsson ME, Atacho D, Karlsson O, Nolbrant S, Parmar M, Jakobsson J. Profiling of lincRNAs in human pluripotent stem cell derived forebrain neural progenitor cells. Heliyon. 6: e03067. PMID 31909251 DOI: 10.1016/J.Heliyon.2019.E03067  0.851
2020 Parmar M, Grealish S, Henchcliffe C. The future of stem cell therapies for Parkinson disease. Nature Reviews. Neuroscience. PMID 31907406 DOI: 10.1038/S41583-019-0257-7  0.836
2019 Davidsson M, Wang G, Aldrin-Kirk P, Cardoso T, Nolbrant S, Hartnor M, Mudannayake J, Parmar M, Björklund T. A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism. Proceedings of the National Academy of Sciences of the United States of America. PMID 31818949 DOI: 10.1073/Pnas.1910061116  0.357
2019 Adler AF, Cardoso T, Nolbrant S, Mattsson B, Hoban DB, Jarl U, Wahlestedt JN, Grealish S, Björklund A, Parmar M. hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson's Disease. Cell Reports. 28: 3462-3473.e5. PMID 31553914 DOI: 10.1016/J.Celrep.2019.08.058  0.845
2019 Birtele M, Sharma Y, Kidnapillai S, Lau S, Stoker T, Barker RA, Rylander Ottosson D, Drouin-Ouellet J, Parmar M. Dual modulation of neuron-specific microRNAs and the REST complex promotes functional maturation of human adult induced neurons. Febs Letters. PMID 31535361 DOI: 10.1002/1873-3468.13612  0.5
2019 De Luca M, Aiuti A, Cossu G, Parmar M, Pellegrini G, Robey PG. Advances in stem cell research and therapeutic development. Nature Cell Biology. PMID 31209293 DOI: 10.1038/S41556-019-0344-Z  0.453
2019 Stacey GN, Andrews PW, Barbaric I, Boiers C, Chandra A, Cossu G, Csontos L, Frith TJ, Halliwell JA, Hewitt Z, McCall M, Moore HD, Parmar M, Panico MB, Pisupati V, et al. Stem cell culture conditions and stability: a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform. Regenerative Medicine. PMID 30938271 DOI: 10.2217/Rme-2019-0001  0.47
2019 Tiklová K, Björklund ÅK, Lahti L, Fiorenzano A, Nolbrant S, Gillberg L, Volakakis N, Yokota C, Hilscher MM, Hauling T, Holmström F, Joodmardi E, Nilsson M, Parmar M, Perlmann T. Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development. Nature Communications. 10: 581. PMID 30718509 DOI: 10.1038/S41467-019-08453-1  0.578
2018 Henchcliffe C, Parmar M. Repairing the Brain: Cell Replacement Using Stem Cell-Based Technologies. Journal of Parkinson's Disease. 8: S131-S137. PMID 30584166 DOI: 10.3233/Jpd-181488  0.579
2018 Parmar M, Torper O, Drouin-Ouellet J. Cell-based therapy for Parkinson's disease: A journey through decades towards the light side of the Force. The European Journal of Neuroscience. PMID 30099795 DOI: 10.1111/Ejn.14109  0.416
2018 Pircs K, Petri R, Madsen S, Brattås PL, Vuono R, Ottosson DR, St-Amour I, Hersbach BA, Matusiak-Brückner M, Lundh SH, Petersén Å, Déglon N, Hébert SS, Parmar M, Barker RA, et al. Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation. Cell Reports. 24: 1397-1406. PMID 30089251 DOI: 10.1016/J.Celrep.2018.07.017  0.602
2018 Cardoso T, Adler A, Mattsson B, Hoban DB, Nolbrant S, Nelander Wahlestedt J, Kirkeby A, Grealish S, Björklund A, Parmar M. Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats. The Journal of Comparative Neurology. PMID 30007046 DOI: 10.1002/Cne.24500  0.842
2018 Hagbard L, Cameron K, August P, Penton C, Parmar M, Hay DC, Kallur T. Developing defined substrates for stem cell culture and differentiation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373. PMID 29786564 DOI: 10.1098/Rstb.2017.0230  0.454
2018 Barker RA, Götz M, Parmar M. New approaches for brain repair-from rescue to reprogramming. Nature. 557: 329-334. PMID 29769670 DOI: 10.1038/S41586-018-0087-1  0.503
2018 Shrigley S, Pircs K, Barker RA, Parmar M, Drouin-Ouellet J. Simple Generation of a High Yield Culture of Induced Neurons from Human Adult Skin Fibroblasts. Journal of Visualized Experiments : Jove. PMID 29443113 DOI: 10.3791/56904  0.53
2018 Parmar M. Towards stem cell based therapies for Parkinson's disease. Development (Cambridge, England). 145. PMID 29311261 DOI: 10.1242/Dev.156117  0.603
2017 Avaliani N, Pfisterer U, Heuer A, Parmar M, Kokaia M, Andersson M. Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus. Stem Cells International. 2017: 5718608. PMID 29317869 DOI: 10.1155/2017/5718608  0.528
2017 Ruetz T, Pfisterer U, Di Stefano B, Ashmore J, Beniazza M, Tian TV, Kaemena DF, Tosti L, Tan W, Manning JR, Chantzoura E, Ottosson DR, Collombet S, Johnsson A, Cohen E, ... ... Parmar M, et al. Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming. Cell Stem Cell. 21: 791-805.e9. PMID 29174331 DOI: 10.1016/J.Stem.2017.10.013  0.468
2017 Barker RA, Parmar M, Studer L, Takahashi J. Human Trials of Stem Cell-Derived Dopamine Neurons for Parkinson's Disease: Dawn of a New Era. Cell Stem Cell. 21: 569-573. PMID 29100010 DOI: 10.1016/J.Stem.2017.09.014  0.571
2017 Drouin-Ouellet J, Pircs K, Barker RA, Jakobsson J, Parmar M. Direct Neuronal Reprogramming for Disease Modeling Studies Using Patient-Derived Neurons: What Have We Learned? Frontiers in Neuroscience. 11: 530. PMID 29033781 DOI: 10.3389/Fnins.2017.00530  0.705
2017 Lehnen D, Barral S, Cardoso T, Grealish S, Heuer A, Smiyakin A, Kirkeby A, Kollet J, Cremer H, Parmar M, Bosio A, Knöbel S. IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells. Stem Cell Reports. PMID 28943253 DOI: 10.1016/J.Stemcr.2017.08.016  0.869
2017 Kikuchi T, Morizane A, Doi D, Magotani H, Onoe H, Hayashi T, Mizuma H, Takara S, Takahashi R, Inoue H, Morita S, Yamamoto M, Okita K, Nakagawa M, Parmar M, et al. Human iPS cell-derived dopaminergic neurons function in a primate Parkinson's disease model. Nature. 548: 592-596. PMID 28858313 DOI: 10.1038/Nature23664  0.596
2017 Nolbrant S, Heuer A, Parmar M, Kirkeby A. Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation. Nature Protocols. 12: 1962-1979. PMID 28858290 DOI: 10.1038/Nprot.2017.078  0.807
2017 Pereira M, Birtele M, Shrigley S, Benitez JA, Hedlund E, Parmar M, Ottosson DR. Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons. Stem Cell Reports. PMID 28844658 DOI: 10.1016/J.Stemcr.2017.07.023  0.552
2017 Moraghebi R, Kirkeby A, Chaves P, Rönn RE, Sitnicka E, Parmar M, Larsson M, Herbst A, Woods NB. Term amniotic fluid: an unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications. Stem Cell Research & Therapy. 8: 190. PMID 28841906 DOI: 10.1186/S13287-017-0582-6  0.723
2017 Drouin-Ouellet J, Lau S, Brattås PL, Rylander Ottosson D, Pircs K, Grassi DA, Collins LM, Vuono R, Andersson Sjöland A, Westergren-Thorsson G, Graff C, Minthon L, Toresson H, Barker RA, Jakobsson J, ... Parmar M, et al. REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways. Embo Molecular Medicine. PMID 28646119 DOI: 10.15252/Emmm.201607471  0.691
2017 Kirkeby A, Parmar M, Barker RA. Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD). Progress in Brain Research. 230: 165-190. PMID 28552228 DOI: 10.1016/Bs.Pbr.2016.11.011  0.775
2017 Tornero D, Tsupykov O, Granmo M, Rodriguez C, Grønning-Hansen M, Thelin J, Smozhanik E, Laterza C, Wattananit S, Ge R, Tatarishvili J, Grealish S, Brüstle O, Skibo G, Parmar M, et al. Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli. Brain : a Journal of Neurology. PMID 28115364 DOI: 10.1093/Brain/Aww347  0.85
2017 Kee N, Volakakis N, Kirkeby A, Dahl L, Storvall H, Nolbrant S, Lahti L, Björklund ÅK, Gillberg L, Joodmardi E, Sandberg R, Parmar M, Perlmann T. Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages. Cell Stem Cell. 20: 29-40. PMID 28094018 DOI: 10.1016/J.Stem.2016.10.003  0.83
2017 Kirkeby A, Nolbrant S, Tiklova K, Heuer A, Kee N, Cardoso T, Ottosson DR, Lelos MJ, Rifes P, Dunnett SB, Grealish S, Perlmann T, Parmar M. Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease. Cell Stem Cell. 20: 135-148. PMID 28094017 DOI: 10.1016/J.Stem.2016.09.004  0.84
2017 Brattås PL, Jönsson ME, Fasching L, Nelander Wahlestedt J, Shahsavani M, Falk R, Falk A, Jern P, Parmar M, Jakobsson J. TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells. Cell Reports. 18: 1-11. PMID 28052240 DOI: 10.1016/J.Celrep.2016.12.010  0.796
2017 Grealish S, Drouin-Ouellet J, Parmar M. Brain repair and reprogramming: the route to clinical translation. Journal of Internal Medicine. 280: 265-75. PMID 27539906 DOI: 10.1111/Joim.12475  0.825
2017 Parmar M, Takahashi J, Studer L, Barker RA. GFORCE-PD still going strong in 2016 Npj Parkinson's Disease. 3. DOI: 10.1038/Npjparkd.2016.14  0.466
2016 Pfisterer U, Ek F, Lang S, Soneji S, Olsson R, Parmar M. Small molecules increase direct neural conversion of human fibroblasts. Scientific Reports. 6: 38290. PMID 27917895 DOI: 10.1038/Srep38290  0.477
2016 Grealish S, Parmar M. Plug and Play Brain: Understanding Integration of Transplanted Neurons for Brain Repair. Cell Stem Cell. 19: 679-680. PMID 27912087 DOI: 10.1016/J.Stem.2016.11.008  0.776
2016 Williams DJ, Archer R, Archibald P, Bantounas I, Baptista R, Barker R, Barry J, Bietrix F, Blair N, Braybrook J, Campbell J, Canham M, Chandra A, Foldes G, Gilmanshin R, ... ... Parmar M, et al. Comparability: manufacturing, characterization and controls, report of a UK Regenerative Medicine Platform Pluripotent Stem Cell Platform Workshop, Trinity Hall, Cambridge, 14-15 September 2015. Regenerative Medicine. PMID 27404768 DOI: 10.2217/Rme-2016-0053  0.334
2016 Heuer A, Jönsson ME, Pfisterer U, Kirkeby A, Parmar M. hESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation. Experimental Neurology. 282: 78-85. PMID 27235932 DOI: 10.1016/J.Expneurol.2016.05.027  0.851
2016 Aldrin-Kirk P, Heuer A, Wang G, Mattsson B, Lundblad M, Parmar M, Björklund T. DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor. Neuron. PMID 27161524 DOI: 10.1016/J.Neuron.2016.04.017  0.449
2016 Barker RA, Parmar M, Kirkeby A, Björklund A, Thompson L, Brundin P. Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016? Journal of Parkinson's Disease. PMID 27003785 DOI: 10.3233/Jpd-160798  0.839
2015 Chen G, Wernig M, Berninger B, Nakafuku M, Parmar M, Zhang CL. In Vivo Reprogramming for Brain and Spinal Cord Repair(1,2,3). Eneuro. 2. PMID 26730402 DOI: 10.1523/ENEURO.0106-15.2015  0.401
2015 Jönsson ME, Nelander Wahlestedt J, Åkerblom M, Kirkeby A, Malmevik J, Brattaas PL, Jakobsson J, Parmar M. Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor. Development (Cambridge, England). 142: 3166-77. PMID 26395143 DOI: 10.1242/Dev.122747  0.782
2015 Barker RA, Drouin-Ouellet J, Parmar M. Cell-based therapies for Parkinson disease—past insights and future potential. Nature Reviews. Neurology. 11: 492-503. PMID 26240036 DOI: 10.1038/Nrneurol.2015.123  0.464
2015 Torper O, Ottosson DR, Pereira M, Lau S, Cardoso T, Grealish S, Parmar M. In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry. Cell Reports. 12: 474-81. PMID 26166567 DOI: 10.1016/J.Celrep.2015.06.040  0.819
2015 Grealish S, Heuer A, Cardoso T, Kirkeby A, Jönsson M, Johansson J, Björklund A, Jakobsson J, Parmar M. Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons. Stem Cell Reports. 4: 975-83. PMID 26004633 DOI: 10.1016/J.Stemcr.2015.04.011  0.844
2015 Aldrin-Kirk P, Heuer A, Mattsson B, Wang G, Lundblad M, Parmar M, Björklund T. 18. Novel Approach Using Fetal Dopaminergic Grafts In Situ Transduced with AAV-DREADDs Significantly Increases Behavioral Motor Recovery in a Rat Model of Parkinson's Disease Molecular Therapy. 23: S8-S9. DOI: 10.1016/S1525-0016(16)33622-X  0.533
2014 Grealish S, Diguet E, Kirkeby A, Mattsson B, Heuer A, Bramoulle Y, Van Camp N, Perrier AL, Hantraye P, Björklund A, Parmar M. Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease. Cell Stem Cell. 15: 653-65. PMID 25517469 DOI: 10.1016/J.Stem.2014.09.017  0.858
2014 Lau S, Rylander Ottosson D, Jakobsson J, Parmar M. Direct neural conversion from human fibroblasts using self-regulating and nonintegrating viral vectors. Cell Reports. 9: 1673-80. PMID 25482564 DOI: 10.1016/J.Celrep.2014.11.017  0.746
2014 Pereira M, Pfisterer U, Rylander D, Torper O, Lau S, Lundblad M, Grealish S, Parmar M. Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain. Scientific Reports. 4: 6330. PMID 25208484 DOI: 10.1038/Srep06330  0.821
2014 Doi D, Samata B, Katsukawa M, Kikuchi T, Morizane A, Ono Y, Sekiguchi K, Nakagawa M, Parmar M, Takahashi J. Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation. Stem Cell Reports. 2: 337-50. PMID 24672756 DOI: 10.1016/J.Stemcr.2014.01.013  0.641
2014 Parmar MS, Jaumotte JD, Wyrostek SL, Zigmond MJ, Cavanaugh JE. Role of ERK1, 2, and 5 in dopamine neuron survival during aging. Neurobiology of Aging. 35: 669-79. PMID 24411019 DOI: 10.1016/J.Neurobiolaging.2013.09.031  0.327
2014 Iovino M, Pfisterer U, Holton JL, Lashley T, Swingler RJ, Calo L, Treacy R, Revesz T, Parmar M, Goedert M, Muqit MM, Spillantini MG. The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons. Acta Neuropathologica. 127: 283-95. PMID 24292008 DOI: 10.1007/S00401-013-1219-1  0.398
2013 Nelander J, Grealish S, Parmar M. Human foetal brain tissue as quality control when developing stem cells towards cell replacement therapy for neurological diseases. Neuroreport. 24: 1025-30. PMID 24257249 DOI: 10.1097/Wnr.0000000000000058  0.828
2013 Torper O, Pfisterer U, Wolf DA, Pereira M, Lau S, Jakobsson J, Björklund A, Grealish S, Parmar M. Generation of induced neurons via direct conversion in vivo. Proceedings of the National Academy of Sciences of the United States of America. 110: 7038-43. PMID 23530235 DOI: 10.1073/Pnas.1303829110  0.879
2013 Ribeiro D, Laguna Goya R, Ravindran G, Vuono R, Parish CL, Foldi C, Piroth T, Yang S, Parmar M, Nikkhah G, Hjerling-Leffler J, Lindvall O, Barker RA, Arenas E. Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens. Neurobiology of Disease. 49: 118-27. PMID 22940632 DOI: 10.1016/J.Nbd.2012.08.006  0.8
2013 Moraghebi R, Kirkeby A, Larsson M, Herbst A, Parmar M, Soneji S, Woods N. X-Reactivation Impacts Human iPSC Differentiation Potential Towards Blood Blood. 122: 4838-4838. DOI: 10.1182/Blood.V122.21.4838.4838  0.746
2012 Kirkeby A, Nelander J, Parmar M. Generating regionalized neuronal cells from pluripotency, a step-by-step protocol. Frontiers in Cellular Neuroscience. 6: 64. PMID 23316134 DOI: 10.3389/Fncel.2012.00064  0.82
2012 Cooper O, Parmar M, Isacson O. Characterization and criteria of embryonic stem and induced pluripotent stem cells for a dopamine replacement therapy. Progress in Brain Research. 200: 265-76. PMID 23195423 DOI: 10.1016/B978-0-444-59575-1.00012-0  0.722
2012 Kirkeby A, Grealish S, Wolf DA, Nelander J, Wood J, Lundblad M, Lindvall O, Parmar M. Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions. Cell Reports. 1: 703-14. PMID 22813745 DOI: 10.1016/J.Celrep.2012.04.009  0.875
2012 Ganat YM, Calder EL, Kriks S, Nelander J, Tu EY, Jia F, Battista D, Harrison N, Parmar M, Tomishima MJ, Rutishauser U, Studer L. Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment. The Journal of Clinical Investigation. 122: 2928-39. PMID 22751106 DOI: 10.1172/Jci58767  0.6
2012 Parmar M, Björklund A. Generation of transplantable striatal projection neurons from human ESCs. Cell Stem Cell. 10: 349-50. PMID 22482498 DOI: 10.1016/J.Stem.2012.03.004  0.604
2012 Kirkeby A, Parmar M. Building authentic midbrain dopaminergic neurons from stem CEllS - Lessons from development Translational Neuroscience. 3: 314-319. DOI: 10.2478/S13380-012-0041-X  0.823
2011 Grealish S, Jakobsson J, Parmar M. Lineage reprogramming: a shortcut to generating functional neurons from fibroblasts. Cell Cycle (Georgetown, Tex.). 10: 3421-2. PMID 22067653 DOI: 10.4161/Cc.10.20.17691  0.862
2011 Pfisterer U, Wood J, Nihlberg K, Hallgren O, Bjermer L, Westergren-Thorsson G, Lindvall O, Parmar M. Efficient induction of functional neurons from adult human fibroblasts. Cell Cycle (Georgetown, Tex.). 10: 3311-6. PMID 21934358 DOI: 10.4161/Cc.10.19.17584  0.735
2011 Parmar M, Jakobsson J. Turning skin into dopamine neurons. Cell Research. 21: 1386-7. PMID 21826107 DOI: 10.1038/Cr.2011.130  0.768
2011 Pfisterer U, Kirkeby A, Torper O, Wood J, Nelander J, Dufour A, Björklund A, Lindvall O, Jakobsson J, Parmar M. Direct conversion of human fibroblasts to dopaminergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 108: 10343-8. PMID 21646515 DOI: 10.1073/Pnas.1105135108  0.858
2010 Brundin P, Barker RA, Parmar M. Neural grafting in Parkinson's disease Problems and possibilities. Progress in Brain Research. 184: 265-94. PMID 20887880 DOI: 10.1016/S0079-6123(10)84014-2  0.624
2010 Sachdeva R, Jönsson ME, Nelander J, Kirkeby A, Guibentif C, Gentner B, Naldini L, Björklund A, Parmar M, Jakobsson J. Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors. Proceedings of the National Academy of Sciences of the United States of America. 107: 11602-7. PMID 20534548 DOI: 10.1073/Pnas.1006568107  0.853
2010 Konstantoulas CJ, Parmar M, Li M. FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3. Journal of Neurochemistry. 113: 836-47. PMID 20175877 DOI: 10.1111/J.1471-4159.2010.06650.X  0.595
2009 Nelander J, Hebsgaard JB, Parmar M. Organization of the human embryonic ventral mesencephalon. Gene Expression Patterns : Gep. 9: 555-61. PMID 19825428 DOI: 10.1016/J.Gep.2009.10.002  0.849
2009 Hebsgaard JB, Nelander J, Sabelström H, Jönsson ME, Stott S, Parmar M. Dopamine neuron precursors within the developing human mesencephalon show radial glial characteristics. Glia. 57: 1648-58. PMID 19330857 DOI: 10.1002/Glia.20877  0.853
2008 Rogelius N, Hebsgaard JB, Lundberg C, Parmar M. Reprogramming of neonatal SVZ progenitors by islet-1 and neurogenin-2. Molecular and Cellular Neurosciences. 38: 453-9. PMID 18524626 DOI: 10.1016/J.Mcn.2008.04.008  0.832
2008 Jönsson M, Parmar M, Thompson L, Björklund A. [P2.62]: Embryonic dopaminergic precursors can be isolated at different states of differentiation and function upon grafting into an animal model of Parkinson's disease International Journal of Developmental Neuroscience. 26: 887-888. DOI: 10.1016/J.Ijdevneu.2008.09.187  0.8
2007 Parmar M, Li M. Early specification of dopaminergic phenotype during ES cell differentiation. Bmc Developmental Biology. 7: 86. PMID 17640353 DOI: 10.1186/1471-213X-7-86  0.586
2007 Andersson EK, Irvin DK, Ahlsiö J, Parmar M. Ngn2 and Nurr1 act in synergy to induce midbrain dopaminergic neurons from expanded neural stem and progenitor cells. Experimental Cell Research. 313: 1172-80. PMID 17291494 DOI: 10.1016/J.Yexcr.2006.12.014  0.868
2007 Cacci E, Villa A, Parmar M, Cavallaro M, Mandahl N, Lindvall O, Martinez-Serrano A, Kokaia Z. Generation of human cortical neurons from a new immortal fetal neural stem cell line. Experimental Cell Research. 313: 588-601. PMID 17156776 DOI: 10.1016/J.Yexcr.2006.11.001  0.723
2007 Barraud P, Stott S, Møllgård K, Parmar M, Björklund A. In vitro characterization of a human neural progenitor cell coexpressing SSEA4 and CD133. Journal of Neuroscience Research. 85: 250-9. PMID 17131412 DOI: 10.1002/Jnr.21116  0.419
2006 Jensen JB, Parmar M. Strengths and limitations of the neurosphere culture system. Molecular Neurobiology. 34: 153-61. PMID 17308349 DOI: 10.1385/Mn:34:3:153  0.464
2006 Rogelius N, Jensen JB, Lundberg C, Parmar M. Retrovirally delivered Islet-1 increases recruitment of Ng2 expressing cells from the postnatal SVZ into the striatum. Experimental Neurology. 201: 388-98. PMID 16806175 DOI: 10.1016/J.Expneurol.2006.04.022  0.788
2006 Thompson LH, Andersson E, Jensen JB, Barraud P, Guillemot F, Parmar M, Björklund A. Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon. Experimental Neurology. 198: 183-98. PMID 16438966 DOI: 10.1016/J.Expneurol.2005.11.025  0.827
2006 Andersson E, Jensen JB, Parmar M, Guillemot F, Björklund A. Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2. Development (Cambridge, England). 133: 507-16. PMID 16396906 DOI: 10.1242/Dev.02224  0.745
2005 Barraud P, Thompson L, Kirik D, Björklund A, Parmar M. Isolation and characterization of neural precursor cells from the Sox1-GFP reporter mouse. The European Journal of Neuroscience. 22: 1555-69. PMID 16197496 DOI: 10.1111/J.1460-9568.2005.04352.X  0.8
2004 Jensen JB, Björklund A, Parmar M. Striatal neuron differentiation from neurosphere-expanded progenitors depends on Gsh2 expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6958-67. PMID 15295031 DOI: 10.1523/Jneurosci.1331-04.2004  0.617
2003 Parmar M, Sjöberg A, Björklund A, Kokaia Z. Phenotypic and molecular identity of cells in the adult subventricular zone. in vivo and after expansion in vitro. Molecular and Cellular Neurosciences. 24: 741-52. PMID 14664822 DOI: 10.1016/S1044-7431(03)00239-2  0.456
2003 Parmar M, Skogh C, Englund U. A transplantation study of expanded human embryonic forebrain precursors: evidence for selection of a specific progenitor population. Molecular and Cellular Neurosciences. 23: 531-43. PMID 12932435 DOI: 10.1016/S1044-7431(03)00097-6  0.512
2003 Skogh C, Parmar M, Campbell K. The differentiation potential of precursor cells from the mouse lateral ganglionic eminence is restricted by in vitro expansion. Neuroscience. 120: 379-85. PMID 12890509 DOI: 10.1016/S0306-4522(03)00427-5  0.762
2002 Parmar M, Skogh C, Björklund A, Campbell K. Regional specification of neurosphere cultures derived from subregions of the embryonic telencephalon. Molecular and Cellular Neurosciences. 21: 645-56. PMID 12504597 DOI: 10.1006/Mcne.2002.1204  0.691
2000 Toresson H, Parmar M, Campbell K. Expression of Meis and Pbx genes and their protein products in the developing telencephalon: implications for regional differentiation. Mechanisms of Development. 94: 183-7. PMID 10842069 DOI: 10.1016/S0925-4773(00)00324-5  0.637
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