| Year |
Citation |
Score |
| 2024 |
Storm P, Zhang Y, Nilsson F, Fiorenzano A, Krausse N, Åkerblom M, Davidsson M, Yuan J, Kirkeby A, Björklund T, Parmar M. Lineage tracing of stem cell-derived dopamine grafts in a Parkinson's model reveals shared origin of all graft-derived cells. Science Advances. 10: eadn3057. PMID 39423273 DOI: 10.1126/sciadv.adn3057 |
0.485 |
|
| 2024 |
Parmar M, Perrier AL. Introduction to stem cell biology and its role in treating neurologic disorders. Handbook of Clinical Neurology. 205: 3-14. PMID 39341661 DOI: 10.1016/B978-0-323-90120-8.00005-8 |
0.477 |
|
| 2024 |
Giacomoni J, Bruzelius A, Habekost M, Kajtez J, Ottosson DR, Fiorenzano A, Storm P, Parmar M. 3D model for human glia conversion into subtype-specific neurons, including dopamine neurons. Cell Reports Methods. 100845. PMID 39236715 DOI: 10.1016/j.crmeth.2024.100845 |
0.47 |
|
| 2024 |
Giacomoni J, Åkerblom M, Habekost M, Fiorenzano A, Kajtez J, Davidsson M, Parmar M, Björklund T. Identification and validation of novel engineered AAV capsid variants targeting human glia. Frontiers in Neuroscience. 18: 1435212. PMID 39193523 DOI: 10.3389/fnins.2024.1435212 |
0.408 |
|
| 2024 |
Barker RA, Björklund A, Parmar M. The history and status of dopamine cell therapies for Parkinson's disease. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e2400118. PMID 39058892 DOI: 10.1002/bies.202400118 |
0.464 |
|
| 2023 |
Reumann D, Krauditsch C, Novatchkova M, Sozzi E, Wong SN, Zabolocki M, Priouret M, Doleschall B, Ritzau-Reid KI, Piber M, Morassut I, Fieseler C, Fiorenzano A, Stevens MM, Zimmer M, ... ... Parmar M, et al. In vitro modeling of the human dopaminergic system using spatially arranged ventral midbrain-striatum-cortex assembloids. Nature Methods. 20: 2034-2047. PMID 38052989 DOI: 10.1038/s41592-023-02080-x |
0.432 |
|
| 2023 |
Kirkeby A, Nelander J, Hoban DB, Rogelius N, Bjartmarz H, Storm P, Fiorenzano A, Adler AF, Vale S, Mudannayake J, Zhang Y, Cardoso T, Mattsson B, Landau AM, Glud AN, ... ... Parmar M, et al. Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD. Cell Stem Cell. 30: 1299-1314.e9. PMID 37802036 DOI: 10.1016/j.stem.2023.08.014 |
0.765 |
|
| 2023 |
Schellino R, Besusso D, Parolisi R, Gómez-González GB, Dallere S, Scaramuzza L, Ribodino M, Campus I, Conforti P, Parmar M, Boido M, Cattaneo E, Buffo A. hESC-derived striatal progenitors grafted into a Huntington's disease rat model support long-term functional motor recovery by differentiating, self-organizing and connecting into the lesioned striatum. Stem Cell Research & Therapy. 14: 189. PMID 37507794 DOI: 10.1186/s13287-023-03422-4 |
0.467 |
|
| 2023 |
Rájová J, Davidsson M, Avallone M, Hartnor M, Aldrin-Kirk P, Cardoso T, Nolbrant S, Mollbrink A, Storm P, Heuer A, Parmar M, Björklund T. Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants . Molecular Therapy. Methods & Clinical Development. 29: 381-394. PMID 37251982 DOI: 10.1016/j.omtm.2023.04.008 |
0.482 |
|
| 2022 |
Sozzi E, Kajtez J, Bruzelius A, Wesseler MF, Nilsson F, Birtele M, Larsen NB, Ottosson DR, Storm P, Parmar M, Fiorenzano A. Silk scaffolding drives self-assembly of functional and mature human brain organoids. Frontiers in Cell and Developmental Biology. 10: 1023279. PMID 36313550 DOI: 10.3389/fcell.2022.1023279 |
0.336 |
|
| 2022 |
Birtele M, Storm P, Sharma Y, Kajtez J, Wahlestedt JN, Sozzi E, Nilsson F, Stott S, He XL, Mattsson B, Ottosson DR, Barker RA, Fiorenzano A, Parmar M. Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain. Development (Cambridge, England). PMID 36305490 DOI: 10.1242/dev.200504 |
0.546 |
|
| 2022 |
Drouin-Ouellet J, Legault EM, Nilsson F, Pircs K, Bouquety J, Petit F, Shrigley S, Birtele M, Pereira M, Storm P, Sharma Y, Bruzelius A, Vuono R, Kele M, Stoker TB, ... ... Parmar M, et al. Age-related pathological impairments in directly reprogrammed dopaminergic neurons derived from patients with idiopathic Parkinson's disease. Stem Cell Reports. PMID 36150382 DOI: 10.1016/j.stemcr.2022.08.010 |
0.677 |
|
| 2022 |
Sozzi E, Nilsson F, Kajtez J, Parmar M, Fiorenzano A. Generation of Human Ventral Midbrain Organoids Derived from Pluripotent Stem Cells. Current Protocols. 2: e555. PMID 36121202 DOI: 10.1002/cpz1.555 |
0.558 |
|
| 2022 |
Kajtez J, Wesseler MF, Birtele M, Khorasgani FR, Rylander Ottosson D, Heiskanen A, Kamperman T, Leijten J, Martínez-Serrano A, Larsen NB, Angelini TE, Parmar M, Lind JU, Emnéus J. Embedded 3D Printing in Self-Healing Annealable Composites for Precise Patterning of Functionally Mature Human Neural Constructs. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2201392. PMID 35712780 DOI: 10.1002/advs.202201392 |
0.343 |
|
| 2022 |
Fiorenzano A, Sozzi E, Birtele M, Kajtez J, Giacomoni J, Nilsson F, Bruzelius A, Sharma Y, Zhang Y, Mattsson B, Emnéus J, Ottosson DR, Storm P, Parmar M. Author Correction: Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids. Nature Communications. 13: 3312. PMID 35676291 DOI: 10.1038/s41467-022-31024-w |
0.44 |
|
| 2022 |
Alekseenko Z, Dias JM, Adler AF, Kozhevnikova M, van Lunteren JA, Nolbrant S, Jeggari A, Vasylovska S, Yoshitake T, Kehr J, Carlén M, Alexeyenko A, Parmar M, Ericson J. Robust derivation of transplantable dopamine neurons from human pluripotent stem cells by timed retinoic acid delivery. Nature Communications. 13: 3046. PMID 35650213 DOI: 10.1038/s41467-022-30777-8 |
0.53 |
|
| 2022 |
Elabi OF, Pass R, Sormonta I, Nolbrant S, Drummond N, Kirkeby A, Kunath T, Parmar M, Lane EL. Human Embryonic Stem Cell-Derived Dopaminergic Grafts Alleviate L-DOPA Induced Dyskinesia. Journal of Parkinson's Disease. PMID 35466951 DOI: 10.3233/JPD-212920 |
0.845 |
|
| 2021 |
Aldrin-Kirk P, Åkerblom M, Cardoso T, Nolbrant S, Adler AF, Liu X, Heuer A, Davidsson M, Parmar M, Björklund T. A novel two-factor monosynaptic TRIO tracing method for assessment of circuit integration of hESC-derived dopamine transplants. Stem Cell Reports. PMID 34971563 DOI: 10.1016/j.stemcr.2021.11.014 |
0.462 |
|
| 2021 |
Pircs K, Drouin-Ouellet J, Horváth V, Gil J, Rezeli M, Garza R, Grassi DA, Sharma Y, St-Amour I, Harris K, Jönsson ME, Johansson PA, Vuono R, Fazal SV, Stoker T, ... ... Parmar M, et al. Distinct subcellular autophagy impairments in induced neurons from Huntington's disease patients. Brain : a Journal of Neurology. PMID 34936701 DOI: 10.1093/brain/awab473 |
0.824 |
|
| 2021 |
Fiorenzano A, Sozzi E, Birtele M, Kajtez J, Giacomoni J, Nilsson F, Bruzelius A, Sharma Y, Zhang Y, Mattsson B, Emnéus J, Ottosson DR, Storm P, Parmar M. Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids. Nature Communications. 12: 7302. PMID 34911939 DOI: 10.1038/s41467-021-27464-5 |
0.485 |
|
| 2021 |
Johansson PA, Brattås PL, Douse CH, Hsieh P, Adami A, Pontis J, Grassi D, Garza R, Sozzi E, Cataldo R, Jönsson ME, Atacho DAM, Pircs K, Eren F, Sharma Y, ... ... Parmar M, et al. A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development. Cell Stem Cell. PMID 34624206 DOI: 10.1016/j.stem.2021.09.008 |
0.798 |
|
| 2021 |
Fiorenzano A, Sozzi E, Parmar M, Storm P. Dopamine Neuron Diversity: Recent Advances and Current Challenges in Human Stem Cell Models and Single Cell Sequencing. Cells. 10. PMID 34206038 DOI: 10.3390/cells10061366 |
0.54 |
|
| 2021 |
Fiorenzano A, Sozzi E, Parmar M, Storm P. Dopamine Neuron Diversity: Recent Advances and Current Challenges in Human Stem Cell Models and Single Cell Sequencing. Cells. 10. PMID 34206038 DOI: 10.3390/cells10061366 |
0.54 |
|
| 2021 |
Parmar M, Björklund A, Björklund T. In vivo conversion of dopamine neurons in mouse models of Parkinson's disease - a future approach for regenerative therapy? Current Opinion in Genetics & Development. 70: 76-82. PMID 34175529 DOI: 10.1016/j.gde.2021.06.002 |
0.482 |
|
| 2021 |
Brambach M, Ernst A, Nolbrant S, Drouin-Ouellet J, Kirkeby A, Parmar M, Olariu V. Neural tube patterning: from a minimal model for rostrocaudal patterning toward an integrated 3D model. Iscience. 24: 102559. PMID 34142058 DOI: 10.1016/j.isci.2021.102559 |
0.688 |
|
| 2021 |
Kajtez J, Nilsson F, Fiorenzano A, Parmar M, Emnéus J. 3D biomaterial models of human brain disease. Neurochemistry International. 105043. PMID 33887378 DOI: 10.1016/j.neuint.2021.105043 |
0.354 |
|
| 2021 |
Björklund A, Parmar M. Dopamine Cell Therapy: From Cell Replacement to Circuitry Repair. Journal of Parkinson's Disease. PMID 33814467 DOI: 10.3233/JPD-212609 |
0.498 |
|
| 2021 |
Fiorenzano A, Birtele M, Wahlestedt JN, Parmar M. Evaluation of -Cre knock-in cell lines for detection and specific targeting of stem cell-derived dopaminergic neurons. Heliyon. 7: e06006. PMID 33532642 DOI: 10.1016/j.heliyon.2021.e06006 |
0.567 |
|
| 2021 |
Nilsson F, Storm P, Sozzi E, Hidalgo Gil D, Birtele M, Sharma Y, Parmar M, Fiorenzano A. Single-Cell Profiling of Coding and Noncoding Genes in Human Dopamine Neuron Differentiation. Cells. 10. PMID 33445654 DOI: 10.3390/cells10010137 |
0.56 |
|
| 2020 |
Shrigley S, Nilsson F, Mattsson B, Fiorenzano A, Mudannayake J, Bruzelius A, Ottosson DR, Björklund A, Hoban DB, Parmar M. Grafts Derived from an α-Synuclein Triplication Patient Mediate Functional Recovery but Develop Disease-Associated Pathology in the 6-OHDA Model of Parkinson's Disease. Journal of Parkinson's Disease. PMID 33361611 DOI: 10.3233/JPD-202366 |
0.428 |
|
| 2020 |
Nolbrant S, Giacomoni J, Hoban DB, Bruzelius A, Birtele M, Chandler-Militello D, Pereira M, Ottosson DR, Goldman SA, Parmar M. Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons. Stem Cell Reports. PMID 32976765 DOI: 10.1016/j.stemcr.2020.08.013 |
0.585 |
|
| 2020 |
Kajtez J, Buchmann S, Vasudevan S, Birtele M, Rocchetti S, Pless CJ, Heiskanen A, Barker RA, Martínez-Serrano A, Parmar M, Lind JU, Emnéus J. 3D-Printed Soft Lithography for Complex Compartmentalized Microfluidic Neural Devices. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 2001150. PMID 32832365 DOI: 10.1002/Advs.202001150 |
0.354 |
|
| 2020 |
Tiklová K, Nolbrant S, Fiorenzano A, Björklund ÅK, Sharma Y, Heuer A, Gillberg L, Hoban DB, Cardoso T, Adler AF, Birtele M, Lundén-Miguel H, Volakakis N, Kirkeby A, Perlmann T, ... Parmar M, et al. Author Correction: Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease. Nature Communications. 11: 3630. PMID 32669619 DOI: 10.1038/S41467-020-17421-Z |
0.752 |
|
| 2020 |
Parmar M, Björklund A. From Skin to Brain: A Parkinson's Disease Patient Transplanted with His Own Cells. Cell Stem Cell. 27: 8-10. PMID 32619520 DOI: 10.1016/J.Stem.2020.06.008 |
0.524 |
|
| 2020 |
Björklund A, Parmar M. Neuronal Replacement as a Tool for Basal Ganglia Circuitry Repair: 40 Years in Perspective. Frontiers in Cellular Neuroscience. 14: 146. PMID 32547369 DOI: 10.3389/Fncel.2020.00146 |
0.522 |
|
| 2020 |
Hoban DB, Shrigley S, Mattsson B, Breger LS, Jarl U, Cardoso T, Nelander Wahlestedt J, Luk KC, Björklund A, Parmar M. Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD. Proceedings of the National Academy of Sciences of the United States of America. PMID 32541058 DOI: 10.1073/Pnas.2001305117 |
0.816 |
|
| 2020 |
Rifes P, Isaksson M, Rathore GS, Aldrin-Kirk P, Møller OK, Barzaghi G, Lee J, Egerod KL, Rausch DM, Parmar M, Pers TH, Laurell T, Kirkeby A. Publisher Correction: Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient. Nature Biotechnology. PMID 32528133 DOI: 10.1038/S41587-020-0590-4 |
0.752 |
|
| 2020 |
Rifes P, Isaksson M, Rathore GS, Aldrin-Kirk P, Møller OK, Barzaghi G, Lee J, Egerod KL, Rausch DM, Parmar M, Pers TH, Laurell T, Kirkeby A. Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient. Nature Biotechnology. PMID 32451506 DOI: 10.1038/S41587-020-0525-0 |
0.768 |
|
| 2020 |
Tiklová K, Nolbrant S, Fiorenzano A, Björklund ÅK, Sharma Y, Heuer A, Gillberg L, Hoban DB, Cardoso T, Adler AF, Birtele M, Lundén-Miguel H, Volakakis N, Kirkeby A, Perlmann T, ... Parmar M, et al. Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease. Nature Communications. 11: 2434. PMID 32415072 DOI: 10.1038/S41467-020-16225-5 |
0.807 |
|
| 2020 |
Besusso D, Schellino R, Boido M, Belloli S, Parolisi R, Conforti P, Faedo A, Cernigoj M, Campus I, Laporta A, Bocchi VD, Murtaj V, Parmar M, Spaiardi P, Talpo F, et al. Stem Cell-Derived Human Striatal Progenitors Innervate Striatal Targets and Alleviate Sensorimotor Deficit in a Rat Model of Huntington Disease. Stem Cell Reports. PMID 32302555 DOI: 10.1016/J.Stemcr.2020.03.018 |
0.563 |
|
| 2020 |
Palma-Tortosa S, Tornero D, Grønning Hansen M, Monni E, Hajy M, Kartsivadze S, Aktay S, Tsupykov O, Parmar M, Deisseroth K, Skibo G, Lindvall O, Kokaia Z. Activity in grafted human iPS cell-derived cortical neurons integrated in stroke-injured rat brain regulates motor behavior. Proceedings of the National Academy of Sciences of the United States of America. PMID 32253308 DOI: 10.1073/Pnas.2000690117 |
0.669 |
|
| 2020 |
Adler AF, Björklund A, Parmar M. Transsynaptic tracing and its emerging use to assess graft-reconstructed neural circuits. Stem Cells (Dayton, Ohio). PMID 32101353 DOI: 10.1002/Stem.3166 |
0.546 |
|
| 2020 |
Grassi DA, Brattås PL, Jönsson ME, Atacho D, Karlsson O, Nolbrant S, Parmar M, Jakobsson J. Profiling of lincRNAs in human pluripotent stem cell derived forebrain neural progenitor cells. Heliyon. 6: e03067. PMID 31909251 DOI: 10.1016/J.Heliyon.2019.E03067 |
0.85 |
|
| 2020 |
Parmar M, Grealish S, Henchcliffe C. The future of stem cell therapies for Parkinson disease. Nature Reviews. Neuroscience. PMID 31907406 DOI: 10.1038/S41583-019-0257-7 |
0.835 |
|
| 2019 |
Davidsson M, Wang G, Aldrin-Kirk P, Cardoso T, Nolbrant S, Hartnor M, Mudannayake J, Parmar M, Björklund T. A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism. Proceedings of the National Academy of Sciences of the United States of America. PMID 31818949 DOI: 10.1073/Pnas.1910061116 |
0.356 |
|
| 2019 |
Adler AF, Cardoso T, Nolbrant S, Mattsson B, Hoban DB, Jarl U, Wahlestedt JN, Grealish S, Björklund A, Parmar M. hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson's Disease. Cell Reports. 28: 3462-3473.e5. PMID 31553914 DOI: 10.1016/J.Celrep.2019.08.058 |
0.845 |
|
| 2019 |
Birtele M, Sharma Y, Kidnapillai S, Lau S, Stoker T, Barker RA, Rylander Ottosson D, Drouin-Ouellet J, Parmar M. Dual modulation of neuron-specific microRNAs and the REST complex promotes functional maturation of human adult induced neurons. Febs Letters. PMID 31535361 DOI: 10.1002/1873-3468.13612 |
0.498 |
|
| 2019 |
De Luca M, Aiuti A, Cossu G, Parmar M, Pellegrini G, Robey PG. Advances in stem cell research and therapeutic development. Nature Cell Biology. PMID 31209293 DOI: 10.1038/S41556-019-0344-Z |
0.453 |
|
| 2019 |
Stacey GN, Andrews PW, Barbaric I, Boiers C, Chandra A, Cossu G, Csontos L, Frith TJ, Halliwell JA, Hewitt Z, McCall M, Moore HD, Parmar M, Panico MB, Pisupati V, et al. Stem cell culture conditions and stability: a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform. Regenerative Medicine. PMID 30938271 DOI: 10.2217/Rme-2019-0001 |
0.47 |
|
| 2019 |
Tiklová K, Björklund ÅK, Lahti L, Fiorenzano A, Nolbrant S, Gillberg L, Volakakis N, Yokota C, Hilscher MM, Hauling T, Holmström F, Joodmardi E, Nilsson M, Parmar M, Perlmann T. Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development. Nature Communications. 10: 581. PMID 30718509 DOI: 10.1038/S41467-019-08453-1 |
0.576 |
|
| 2018 |
Henchcliffe C, Parmar M. Repairing the Brain: Cell Replacement Using Stem Cell-Based Technologies. Journal of Parkinson's Disease. 8: S131-S137. PMID 30584166 DOI: 10.3233/Jpd-181488 |
0.578 |
|
| 2018 |
Parmar M, Torper O, Drouin-Ouellet J. Cell-based therapy for Parkinson's disease: A journey through decades towards the light side of the Force. The European Journal of Neuroscience. PMID 30099795 DOI: 10.1111/Ejn.14109 |
0.418 |
|
| 2018 |
Pircs K, Petri R, Madsen S, Brattås PL, Vuono R, Ottosson DR, St-Amour I, Hersbach BA, Matusiak-Brückner M, Lundh SH, Petersén Å, Déglon N, Hébert SS, Parmar M, Barker RA, et al. Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation. Cell Reports. 24: 1397-1406. PMID 30089251 DOI: 10.1016/J.Celrep.2018.07.017 |
0.6 |
|
| 2018 |
Cardoso T, Adler A, Mattsson B, Hoban DB, Nolbrant S, Nelander Wahlestedt J, Kirkeby A, Grealish S, Björklund A, Parmar M. Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats. The Journal of Comparative Neurology. PMID 30007046 DOI: 10.1002/Cne.24500 |
0.842 |
|
| 2018 |
Hagbard L, Cameron K, August P, Penton C, Parmar M, Hay DC, Kallur T. Developing defined substrates for stem cell culture and differentiation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373. PMID 29786564 DOI: 10.1098/Rstb.2017.0230 |
0.453 |
|
| 2018 |
Barker RA, Götz M, Parmar M. New approaches for brain repair-from rescue to reprogramming. Nature. 557: 329-334. PMID 29769670 DOI: 10.1038/S41586-018-0087-1 |
0.502 |
|
| 2018 |
Shrigley S, Pircs K, Barker RA, Parmar M, Drouin-Ouellet J. Simple Generation of a High Yield Culture of Induced Neurons from Human Adult Skin Fibroblasts. Journal of Visualized Experiments : Jove. PMID 29443113 DOI: 10.3791/56904 |
0.528 |
|
| 2018 |
Parmar M. Towards stem cell based therapies for Parkinson's disease. Development (Cambridge, England). 145. PMID 29311261 DOI: 10.1242/Dev.156117 |
0.603 |
|
| 2017 |
Avaliani N, Pfisterer U, Heuer A, Parmar M, Kokaia M, Andersson M. Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus. Stem Cells International. 2017: 5718608. PMID 29317869 DOI: 10.1155/2017/5718608 |
0.526 |
|
| 2017 |
Ruetz T, Pfisterer U, Di Stefano B, Ashmore J, Beniazza M, Tian TV, Kaemena DF, Tosti L, Tan W, Manning JR, Chantzoura E, Ottosson DR, Collombet S, Johnsson A, Cohen E, ... ... Parmar M, et al. Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming. Cell Stem Cell. 21: 791-805.e9. PMID 29174331 DOI: 10.1016/J.Stem.2017.10.013 |
0.466 |
|
| 2017 |
Barker RA, Parmar M, Studer L, Takahashi J. Human Trials of Stem Cell-Derived Dopamine Neurons for Parkinson's Disease: Dawn of a New Era. Cell Stem Cell. 21: 569-573. PMID 29100010 DOI: 10.1016/J.Stem.2017.09.014 |
0.573 |
|
| 2017 |
Drouin-Ouellet J, Pircs K, Barker RA, Jakobsson J, Parmar M. Direct Neuronal Reprogramming for Disease Modeling Studies Using Patient-Derived Neurons: What Have We Learned? Frontiers in Neuroscience. 11: 530. PMID 29033781 DOI: 10.3389/Fnins.2017.00530 |
0.702 |
|
| 2017 |
Lehnen D, Barral S, Cardoso T, Grealish S, Heuer A, Smiyakin A, Kirkeby A, Kollet J, Cremer H, Parmar M, Bosio A, Knöbel S. IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells. Stem Cell Reports. PMID 28943253 DOI: 10.1016/J.Stemcr.2017.08.016 |
0.869 |
|
| 2017 |
Kikuchi T, Morizane A, Doi D, Magotani H, Onoe H, Hayashi T, Mizuma H, Takara S, Takahashi R, Inoue H, Morita S, Yamamoto M, Okita K, Nakagawa M, Parmar M, et al. Human iPS cell-derived dopaminergic neurons function in a primate Parkinson's disease model. Nature. 548: 592-596. PMID 28858313 DOI: 10.1038/Nature23664 |
0.598 |
|
| 2017 |
Nolbrant S, Heuer A, Parmar M, Kirkeby A. Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation. Nature Protocols. 12: 1962-1979. PMID 28858290 DOI: 10.1038/Nprot.2017.078 |
0.8 |
|
| 2017 |
Pereira M, Birtele M, Shrigley S, Benitez JA, Hedlund E, Parmar M, Ottosson DR. Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons. Stem Cell Reports. PMID 28844658 DOI: 10.1016/J.Stemcr.2017.07.023 |
0.55 |
|
| 2017 |
Moraghebi R, Kirkeby A, Chaves P, Rönn RE, Sitnicka E, Parmar M, Larsson M, Herbst A, Woods NB. Term amniotic fluid: an unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications. Stem Cell Research & Therapy. 8: 190. PMID 28841906 DOI: 10.1186/S13287-017-0582-6 |
0.713 |
|
| 2017 |
Drouin-Ouellet J, Lau S, Brattås PL, Rylander Ottosson D, Pircs K, Grassi DA, Collins LM, Vuono R, Andersson Sjöland A, Westergren-Thorsson G, Graff C, Minthon L, Toresson H, Barker RA, Jakobsson J, ... Parmar M, et al. REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways. Embo Molecular Medicine. PMID 28646119 DOI: 10.15252/Emmm.201607471 |
0.688 |
|
| 2017 |
Kirkeby A, Parmar M, Barker RA. Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD). Progress in Brain Research. 230: 165-190. PMID 28552228 DOI: 10.1016/Bs.Pbr.2016.11.011 |
0.769 |
|
| 2017 |
Tornero D, Tsupykov O, Granmo M, Rodriguez C, Grønning-Hansen M, Thelin J, Smozhanik E, Laterza C, Wattananit S, Ge R, Tatarishvili J, Grealish S, Brüstle O, Skibo G, Parmar M, et al. Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli. Brain : a Journal of Neurology. PMID 28115364 DOI: 10.1093/Brain/Aww347 |
0.849 |
|
| 2017 |
Kee N, Volakakis N, Kirkeby A, Dahl L, Storvall H, Nolbrant S, Lahti L, Björklund ÅK, Gillberg L, Joodmardi E, Sandberg R, Parmar M, Perlmann T. Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages. Cell Stem Cell. 20: 29-40. PMID 28094018 DOI: 10.1016/J.Stem.2016.10.003 |
0.824 |
|
| 2017 |
Kirkeby A, Nolbrant S, Tiklova K, Heuer A, Kee N, Cardoso T, Ottosson DR, Lelos MJ, Rifes P, Dunnett SB, Grealish S, Perlmann T, Parmar M. Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease. Cell Stem Cell. 20: 135-148. PMID 28094017 DOI: 10.1016/J.Stem.2016.09.004 |
0.84 |
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| 2017 |
Brattås PL, Jönsson ME, Fasching L, Nelander Wahlestedt J, Shahsavani M, Falk R, Falk A, Jern P, Parmar M, Jakobsson J. TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells. Cell Reports. 18: 1-11. PMID 28052240 DOI: 10.1016/J.Celrep.2016.12.010 |
0.796 |
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| 2017 |
Grealish S, Drouin-Ouellet J, Parmar M. Brain repair and reprogramming: the route to clinical translation. Journal of Internal Medicine. 280: 265-75. PMID 27539906 DOI: 10.1111/Joim.12475 |
0.825 |
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| 2017 |
Parmar M, Takahashi J, Studer L, Barker RA. GFORCE-PD still going strong in 2016 Npj Parkinson's Disease. 3. DOI: 10.1038/Npjparkd.2016.14 |
0.47 |
|
| 2016 |
Pfisterer U, Ek F, Lang S, Soneji S, Olsson R, Parmar M. Small molecules increase direct neural conversion of human fibroblasts. Scientific Reports. 6: 38290. PMID 27917895 DOI: 10.1038/Srep38290 |
0.475 |
|
| 2016 |
Grealish S, Parmar M. Plug and Play Brain: Understanding Integration of Transplanted Neurons for Brain Repair. Cell Stem Cell. 19: 679-680. PMID 27912087 DOI: 10.1016/J.Stem.2016.11.008 |
0.776 |
|
| 2016 |
Williams DJ, Archer R, Archibald P, Bantounas I, Baptista R, Barker R, Barry J, Bietrix F, Blair N, Braybrook J, Campbell J, Canham M, Chandra A, Foldes G, Gilmanshin R, ... ... Parmar M, et al. Comparability: manufacturing, characterization and controls, report of a UK Regenerative Medicine Platform Pluripotent Stem Cell Platform Workshop, Trinity Hall, Cambridge, 14-15 September 2015. Regenerative Medicine. PMID 27404768 DOI: 10.2217/Rme-2016-0053 |
0.334 |
|
| 2016 |
Heuer A, Jönsson ME, Pfisterer U, Kirkeby A, Parmar M. hESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation. Experimental Neurology. 282: 78-85. PMID 27235932 DOI: 10.1016/J.Expneurol.2016.05.027 |
0.852 |
|
| 2016 |
Aldrin-Kirk P, Heuer A, Wang G, Mattsson B, Lundblad M, Parmar M, Björklund T. DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor. Neuron. PMID 27161524 DOI: 10.1016/J.Neuron.2016.04.017 |
0.45 |
|
| 2016 |
Barker RA, Parmar M, Kirkeby A, Björklund A, Thompson L, Brundin P. Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016? Journal of Parkinson's Disease. PMID 27003785 DOI: 10.3233/Jpd-160798 |
0.836 |
|
| 2015 |
Chen G, Wernig M, Berninger B, Nakafuku M, Parmar M, Zhang CL. In Vivo Reprogramming for Brain and Spinal Cord Repair(1,2,3). Eneuro. 2. PMID 26730402 DOI: 10.1523/ENEURO.0106-15.2015 |
0.399 |
|
| 2015 |
Jönsson ME, Nelander Wahlestedt J, Åkerblom M, Kirkeby A, Malmevik J, Brattaas PL, Jakobsson J, Parmar M. Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor. Development (Cambridge, England). 142: 3166-77. PMID 26395143 DOI: 10.1242/Dev.122747 |
0.782 |
|
| 2015 |
Barker RA, Drouin-Ouellet J, Parmar M. Cell-based therapies for Parkinson disease—past insights and future potential. Nature Reviews. Neurology. 11: 492-503. PMID 26240036 DOI: 10.1038/Nrneurol.2015.123 |
0.466 |
|
| 2015 |
Torper O, Ottosson DR, Pereira M, Lau S, Cardoso T, Grealish S, Parmar M. In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry. Cell Reports. 12: 474-81. PMID 26166567 DOI: 10.1016/J.Celrep.2015.06.040 |
0.818 |
|
| 2015 |
Grealish S, Heuer A, Cardoso T, Kirkeby A, Jönsson M, Johansson J, Björklund A, Jakobsson J, Parmar M. Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons. Stem Cell Reports. 4: 975-83. PMID 26004633 DOI: 10.1016/J.Stemcr.2015.04.011 |
0.845 |
|
| 2015 |
Aldrin-Kirk P, Heuer A, Mattsson B, Wang G, Lundblad M, Parmar M, Björklund T. 18. Novel Approach Using Fetal Dopaminergic Grafts In Situ Transduced with AAV-DREADDs Significantly Increases Behavioral Motor Recovery in a Rat Model of Parkinson's Disease Molecular Therapy. 23: S8-S9. DOI: 10.1016/S1525-0016(16)33622-X |
0.532 |
|
| 2014 |
Grealish S, Diguet E, Kirkeby A, Mattsson B, Heuer A, Bramoulle Y, Van Camp N, Perrier AL, Hantraye P, Björklund A, Parmar M. Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease. Cell Stem Cell. 15: 653-65. PMID 25517469 DOI: 10.1016/J.Stem.2014.09.017 |
0.858 |
|
| 2014 |
Lau S, Rylander Ottosson D, Jakobsson J, Parmar M. Direct neural conversion from human fibroblasts using self-regulating and nonintegrating viral vectors. Cell Reports. 9: 1673-80. PMID 25482564 DOI: 10.1016/J.Celrep.2014.11.017 |
0.743 |
|
| 2014 |
Pereira M, Pfisterer U, Rylander D, Torper O, Lau S, Lundblad M, Grealish S, Parmar M. Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain. Scientific Reports. 4: 6330. PMID 25208484 DOI: 10.1038/Srep06330 |
0.821 |
|
| 2014 |
Doi D, Samata B, Katsukawa M, Kikuchi T, Morizane A, Ono Y, Sekiguchi K, Nakagawa M, Parmar M, Takahashi J. Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation. Stem Cell Reports. 2: 337-50. PMID 24672756 DOI: 10.1016/J.Stemcr.2014.01.013 |
0.639 |
|
| 2014 |
Parmar MS, Jaumotte JD, Wyrostek SL, Zigmond MJ, Cavanaugh JE. Role of ERK1, 2, and 5 in dopamine neuron survival during aging. Neurobiology of Aging. 35: 669-79. PMID 24411019 DOI: 10.1016/J.Neurobiolaging.2013.09.031 |
0.325 |
|
| 2014 |
Iovino M, Pfisterer U, Holton JL, Lashley T, Swingler RJ, Calo L, Treacy R, Revesz T, Parmar M, Goedert M, Muqit MM, Spillantini MG. The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons. Acta Neuropathologica. 127: 283-95. PMID 24292008 DOI: 10.1007/S00401-013-1219-1 |
0.398 |
|
| 2013 |
Nelander J, Grealish S, Parmar M. Human foetal brain tissue as quality control when developing stem cells towards cell replacement therapy for neurological diseases. Neuroreport. 24: 1025-30. PMID 24257249 DOI: 10.1097/Wnr.0000000000000058 |
0.828 |
|
| 2013 |
Torper O, Pfisterer U, Wolf DA, Pereira M, Lau S, Jakobsson J, Björklund A, Grealish S, Parmar M. Generation of induced neurons via direct conversion in vivo. Proceedings of the National Academy of Sciences of the United States of America. 110: 7038-43. PMID 23530235 DOI: 10.1073/Pnas.1303829110 |
0.879 |
|
| 2013 |
Ribeiro D, Laguna Goya R, Ravindran G, Vuono R, Parish CL, Foldi C, Piroth T, Yang S, Parmar M, Nikkhah G, Hjerling-Leffler J, Lindvall O, Barker RA, Arenas E. Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens. Neurobiology of Disease. 49: 118-27. PMID 22940632 DOI: 10.1016/J.Nbd.2012.08.006 |
0.799 |
|
| 2013 |
Moraghebi R, Kirkeby A, Larsson M, Herbst A, Parmar M, Soneji S, Woods N. X-Reactivation Impacts Human iPSC Differentiation Potential Towards Blood Blood. 122: 4838-4838. DOI: 10.1182/Blood.V122.21.4838.4838 |
0.736 |
|
| 2012 |
Kirkeby A, Nelander J, Parmar M. Generating regionalized neuronal cells from pluripotency, a step-by-step protocol. Frontiers in Cellular Neuroscience. 6: 64. PMID 23316134 DOI: 10.3389/Fncel.2012.00064 |
0.814 |
|
| 2012 |
Cooper O, Parmar M, Isacson O. Characterization and criteria of embryonic stem and induced pluripotent stem cells for a dopamine replacement therapy. Progress in Brain Research. 200: 265-76. PMID 23195423 DOI: 10.1016/B978-0-444-59575-1.00012-0 |
0.722 |
|
| 2012 |
Kirkeby A, Grealish S, Wolf DA, Nelander J, Wood J, Lundblad M, Lindvall O, Parmar M. Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions. Cell Reports. 1: 703-14. PMID 22813745 DOI: 10.1016/J.Celrep.2012.04.009 |
0.875 |
|
| 2012 |
Ganat YM, Calder EL, Kriks S, Nelander J, Tu EY, Jia F, Battista D, Harrison N, Parmar M, Tomishima MJ, Rutishauser U, Studer L. Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment. The Journal of Clinical Investigation. 122: 2928-39. PMID 22751106 DOI: 10.1172/Jci58767 |
0.598 |
|
| 2012 |
Parmar M, Björklund A. Generation of transplantable striatal projection neurons from human ESCs. Cell Stem Cell. 10: 349-50. PMID 22482498 DOI: 10.1016/J.Stem.2012.03.004 |
0.602 |
|
| 2012 |
Kirkeby A, Parmar M. Building authentic midbrain dopaminergic neurons from stem CEllS - Lessons from development Translational Neuroscience. 3: 314-319. DOI: 10.2478/S13380-012-0041-X |
0.817 |
|
| 2011 |
Grealish S, Jakobsson J, Parmar M. Lineage reprogramming: a shortcut to generating functional neurons from fibroblasts. Cell Cycle (Georgetown, Tex.). 10: 3421-2. PMID 22067653 DOI: 10.4161/Cc.10.20.17691 |
0.862 |
|
| 2011 |
Pfisterer U, Wood J, Nihlberg K, Hallgren O, Bjermer L, Westergren-Thorsson G, Lindvall O, Parmar M. Efficient induction of functional neurons from adult human fibroblasts. Cell Cycle (Georgetown, Tex.). 10: 3311-6. PMID 21934358 DOI: 10.4161/Cc.10.19.17584 |
0.733 |
|
| 2011 |
Parmar M, Jakobsson J. Turning skin into dopamine neurons. Cell Research. 21: 1386-7. PMID 21826107 DOI: 10.1038/Cr.2011.130 |
0.766 |
|
| 2011 |
Pfisterer U, Kirkeby A, Torper O, Wood J, Nelander J, Dufour A, Björklund A, Lindvall O, Jakobsson J, Parmar M. Direct conversion of human fibroblasts to dopaminergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 108: 10343-8. PMID 21646515 DOI: 10.1073/Pnas.1105135108 |
0.858 |
|
| 2010 |
Brundin P, Barker RA, Parmar M. Neural grafting in Parkinson's disease Problems and possibilities. Progress in Brain Research. 184: 265-94. PMID 20887880 DOI: 10.1016/S0079-6123(10)84014-2 |
0.626 |
|
| 2010 |
Sachdeva R, Jönsson ME, Nelander J, Kirkeby A, Guibentif C, Gentner B, Naldini L, Björklund A, Parmar M, Jakobsson J. Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors. Proceedings of the National Academy of Sciences of the United States of America. 107: 11602-7. PMID 20534548 DOI: 10.1073/Pnas.1006568107 |
0.853 |
|
| 2010 |
Konstantoulas CJ, Parmar M, Li M. FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3. Journal of Neurochemistry. 113: 836-47. PMID 20175877 DOI: 10.1111/J.1471-4159.2010.06650.X |
0.594 |
|
| 2009 |
Nelander J, Hebsgaard JB, Parmar M. Organization of the human embryonic ventral mesencephalon. Gene Expression Patterns : Gep. 9: 555-61. PMID 19825428 DOI: 10.1016/J.Gep.2009.10.002 |
0.848 |
|
| 2009 |
Hebsgaard JB, Nelander J, Sabelström H, Jönsson ME, Stott S, Parmar M. Dopamine neuron precursors within the developing human mesencephalon show radial glial characteristics. Glia. 57: 1648-58. PMID 19330857 DOI: 10.1002/Glia.20877 |
0.853 |
|
| 2008 |
Rogelius N, Hebsgaard JB, Lundberg C, Parmar M. Reprogramming of neonatal SVZ progenitors by islet-1 and neurogenin-2. Molecular and Cellular Neurosciences. 38: 453-9. PMID 18524626 DOI: 10.1016/J.Mcn.2008.04.008 |
0.831 |
|
| 2008 |
Jönsson M, Parmar M, Thompson L, Björklund A. [P2.62]: Embryonic dopaminergic precursors can be isolated at different states of differentiation and function upon grafting into an animal model of Parkinson's disease International Journal of Developmental Neuroscience. 26: 887-888. DOI: 10.1016/J.Ijdevneu.2008.09.187 |
0.801 |
|
| 2007 |
Parmar M, Li M. Early specification of dopaminergic phenotype during ES cell differentiation. Bmc Developmental Biology. 7: 86. PMID 17640353 DOI: 10.1186/1471-213X-7-86 |
0.585 |
|
| 2007 |
Andersson EK, Irvin DK, Ahlsiö J, Parmar M. Ngn2 and Nurr1 act in synergy to induce midbrain dopaminergic neurons from expanded neural stem and progenitor cells. Experimental Cell Research. 313: 1172-80. PMID 17291494 DOI: 10.1016/J.Yexcr.2006.12.014 |
0.868 |
|
| 2007 |
Cacci E, Villa A, Parmar M, Cavallaro M, Mandahl N, Lindvall O, Martinez-Serrano A, Kokaia Z. Generation of human cortical neurons from a new immortal fetal neural stem cell line. Experimental Cell Research. 313: 588-601. PMID 17156776 DOI: 10.1016/J.Yexcr.2006.11.001 |
0.721 |
|
| 2007 |
Barraud P, Stott S, Møllgård K, Parmar M, Björklund A. In vitro characterization of a human neural progenitor cell coexpressing SSEA4 and CD133. Journal of Neuroscience Research. 85: 250-9. PMID 17131412 DOI: 10.1002/Jnr.21116 |
0.418 |
|
| 2006 |
Jensen JB, Parmar M. Strengths and limitations of the neurosphere culture system. Molecular Neurobiology. 34: 153-61. PMID 17308349 DOI: 10.1385/Mn:34:3:153 |
0.463 |
|
| 2006 |
Rogelius N, Jensen JB, Lundberg C, Parmar M. Retrovirally delivered Islet-1 increases recruitment of Ng2 expressing cells from the postnatal SVZ into the striatum. Experimental Neurology. 201: 388-98. PMID 16806175 DOI: 10.1016/J.Expneurol.2006.04.022 |
0.787 |
|
| 2006 |
Thompson LH, Andersson E, Jensen JB, Barraud P, Guillemot F, Parmar M, Björklund A. Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon. Experimental Neurology. 198: 183-98. PMID 16438966 DOI: 10.1016/J.Expneurol.2005.11.025 |
0.825 |
|
| 2006 |
Andersson E, Jensen JB, Parmar M, Guillemot F, Björklund A. Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2. Development (Cambridge, England). 133: 507-16. PMID 16396906 DOI: 10.1242/Dev.02224 |
0.743 |
|
| 2005 |
Barraud P, Thompson L, Kirik D, Björklund A, Parmar M. Isolation and characterization of neural precursor cells from the Sox1-GFP reporter mouse. The European Journal of Neuroscience. 22: 1555-69. PMID 16197496 DOI: 10.1111/J.1460-9568.2005.04352.X |
0.799 |
|
| 2004 |
Jensen JB, Björklund A, Parmar M. Striatal neuron differentiation from neurosphere-expanded progenitors depends on Gsh2 expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6958-67. PMID 15295031 DOI: 10.1523/Jneurosci.1331-04.2004 |
0.615 |
|
| 2003 |
Parmar M, Sjöberg A, Björklund A, Kokaia Z. Phenotypic and molecular identity of cells in the adult subventricular zone. in vivo and after expansion in vitro. Molecular and Cellular Neurosciences. 24: 741-52. PMID 14664822 DOI: 10.1016/S1044-7431(03)00239-2 |
0.455 |
|
| 2003 |
Parmar M, Skogh C, Englund U. A transplantation study of expanded human embryonic forebrain precursors: evidence for selection of a specific progenitor population. Molecular and Cellular Neurosciences. 23: 531-43. PMID 12932435 DOI: 10.1016/S1044-7431(03)00097-6 |
0.51 |
|
| 2003 |
Skogh C, Parmar M, Campbell K. The differentiation potential of precursor cells from the mouse lateral ganglionic eminence is restricted by in vitro expansion. Neuroscience. 120: 379-85. PMID 12890509 DOI: 10.1016/S0306-4522(03)00427-5 |
0.758 |
|
| 2002 |
Parmar M, Skogh C, Björklund A, Campbell K. Regional specification of neurosphere cultures derived from subregions of the embryonic telencephalon. Molecular and Cellular Neurosciences. 21: 645-56. PMID 12504597 DOI: 10.1006/Mcne.2002.1204 |
0.686 |
|
| 2000 |
Toresson H, Parmar M, Campbell K. Expression of Meis and Pbx genes and their protein products in the developing telencephalon: implications for regional differentiation. Mechanisms of Development. 94: 183-7. PMID 10842069 DOI: 10.1016/S0925-4773(00)00324-5 |
0.631 |
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