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Dennis L. Murphy - Publications

Affiliations: 
NIMH/NIH National Institute of Health, Bethesda, MD, United States 
Area:
OCD, serotonin transporter
Website:
http://neuroscience.nih.gov/Lab.asp?Org_ID=172

308 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Samuels J, Bienvenu OJ, Krasnow J, Wang Y, Grados MA, Cullen B, Goes FS, Maher B, Greenberg BD, Mclaughlin NC, Rasmussen SA, Fyer AJ, Knowles JA, Mccracken JT, Piacentini J, ... ... Murphy DL, et al. General personality dimensions, impairment and treatment response in obsessive-compulsive disorder. Personality and Mental Health. PMID 31859455 DOI: 10.1002/Pmh.1472  0.324
2019 Delgado-Acevedo C, Estay SF, Radke AK, Sengupta A, Escobar AP, Henríquez-Belmar F, Reyes CA, Haro-Acuña V, Utreras E, Sotomayor-Zárate R, Cho A, Wendland JR, Kulkarni AB, Holmes A, Murphy DL, et al. Correction: Behavioral and synaptic alterations relevant to obsessivecompulsive disorder in mice with increased EAAT3 expression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30787427 DOI: 10.1038/s41386-019-0331-x  0.639
2018 Delgado-Acevedo C, Estay SF, Radke A, Sengupta A, Escobar AP, Henríquez-Belmar F, Reyes C, Haro V, Utreras E, Sotomayor-Zárate R, Cho A, Wendland JR, Kulkarni AB, Holmes A, Murphy DL, et al. Behavioral and synaptic alterations relevant to obsessive-compulsive disorder in mice with increased EAAT3 expression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30622300 DOI: 10.1038/S41386-018-0302-7  0.701
2018 Tanaka M, Sato A, Kasai S, Hagino Y, Kotajima-Murakami H, Kashii H, Takamatsu Y, Nishito Y, Inagaki M, Mizuguchi M, Hall FS, Uhl GR, Murphy D, Sora I, Ikeda K. Brain hyperserotonemia causes autism-relevant social deficits in mice. Molecular Autism. 9: 60. PMID 30498565 DOI: 10.1186/S13229-018-0243-3  0.324
2017 Samuels J, Bienvenu OJ, Krasnow J, Wang Y, Grados MA, Cullen B, Goes FS, Maher B, Greenberg BD, McLaughlin NC, Rasmussen SA, Fyer AJ, Knowles JA, McCracken JT, Piacentini J, ... ... Murphy DL, et al. Self-reported executive function and hoarding in adults with obsessive-compulsive disorder. Comprehensive Psychiatry. 81: 53-59. PMID 29268152 DOI: 10.1016/J.Comppsych.2017.11.009  0.314
2017 González LF, Henríquez-Belmar F, Delgado-Acevedo C, Cisternas-Olmedo M, Arriagada G, Sotomayor-Zárate R, Murphy DL, Moya PR. Neurochemical and behavioral characterization of neuronal glutamate transporter EAAT3 heterozygous mice. Biological Research. 50: 29. PMID 28927446 DOI: 10.1186/S40659-017-0138-3  0.703
2017 Samuels J, Bienvenu OJ, Krasnow J, Wang Y, Grados MA, Cullen B, Goes FS, Maher B, Greenberg BD, McLaughlin NC, Rasmussen SA, Fyer AJ, Knowles JA, Nestadt P, McCracken JT, ... ... Murphy DL, et al. An investigation of doubt in obsessive-compulsive disorder. Comprehensive Psychiatry. 75: 117-124. PMID 28359017 DOI: 10.1016/J.Comppsych.2017.03.004  0.301
2015 Mroczkowski MM, Goes FS, Riddle MA, Grados MA, Bienvenu OJ, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Knowles JA, Piacentini J, Cullen B, Rasmussen SA, Pauls DL, et al. Dependent personality, separation anxiety disorder and other anxiety disorders in OCD. Personality and Mental Health. PMID 26542617 DOI: 10.1002/Pmh.1321  0.304
2015 Piao YS, Hall FS, Moriya Y, Ito M, Ohara A, Kikura-Hanajiri R, Goda Y, Lesch KP, Murphy DL, Uhl GR, Sora I. Methylone-induced hyperthermia and lethal toxicity: role of the dopamine and serotonin transporters. Behavioural Pharmacology. 26: 345-52. PMID 25794333 DOI: 10.1097/Fbp.0000000000000135  0.328
2015 Igari M, Shen HW, Hagino Y, Fukushima S, Kasahara Y, Lesch KP, Murphy DL, Hall FS, Uhl GR, Ikeda K, Yaegashi N, Sora I. Attenuated methamphetamine-induced locomotor sensitization in serotonin transporter knockout mice is restored by serotonin 1B receptor antagonist treatment. Behavioural Pharmacology. 26: 167-79. PMID 25485646 DOI: 10.1097/Fbp.0000000000000120  0.37
2014 Sakakibara Y, Kasahara Y, Hall FS, Lesch KP, Murphy DL, Uhl GR, Sora I. Developmental alterations in anxiety and cognitive behavior in serotonin transporter mutant mice. Psychopharmacology. 231: 4119-33. PMID 24728652 DOI: 10.1007/S00213-014-3554-X  0.365
2013 Ozomaro U, Cai G, Kajiwara Y, Yoon S, Makarov V, Delorme R, Betancur C, Ruhrmann S, Falkai P, Grabe HJ, Maier W, Wagner M, Lennertz L, Moessner R, Murphy DL, et al. Characterization of SLITRK1 variation in obsessive-compulsive disorder. Plos One. 8: e70376. PMID 23990902 DOI: 10.1371/Journal.Pone.0070376  0.327
2013 Moya PR, Wendland JR, Rubenstein LM, Timpano KR, Heiman GA, Tischfield JA, King RA, Andrews AM, Ramamoorthy S, McMahon FJ, Murphy DL. Common and rare alleles of the serotonin transporter gene, SLC6A4, associated with Tourette's disorder. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 1263-70. PMID 23630162 DOI: 10.1002/Mds.25460  0.744
2013 Stewart SE, Mayerfeld C, Arnold PD, Crane JR, O'Dushlaine C, Fagerness JA, Yu D, Scharf JM, Chan E, Kassam F, Moya PR, Wendland JR, Delorme R, Richter MA, Kennedy JL, ... ... Murphy DL, et al. Meta-analysis of association between obsessive-compulsive disorder and the 3' region of neuronal glutamate transporter gene SLC1A1. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 162: 367-79. PMID 23606572 DOI: 10.1002/Ajmg.B.32137  0.682
2013 Murphy DL, Moya PR, Fox MA, Rubenstein LM, Wendland JR, Timpano KR. Anxiety and affective disorder comorbidity related to serotonin and other neurotransmitter systems: obsessive-compulsive disorder as an example of overlapping clinical and genetic heterogeneity. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20120435. PMID 23440468 DOI: 10.1098/Rstb.2012.0435  0.699
2013 Fox MA, Panessiti MG, Hall FS, Uhl GR, Murphy DL. An evaluation of the serotonin system and perseverative, compulsive, stereotypical, and hyperactive behaviors in dopamine transporter (DAT) knockout mice. Psychopharmacology. 227: 685-95. PMID 23417514 DOI: 10.1007/S00213-013-2988-X  0.328
2013 Fox MA, Panessiti MG, Moya PR, Tolliver TJ, Chen K, Shih JC, Murphy DL. Mutations in monoamine oxidase (MAO) genes in mice lead to hypersensitivity to serotonin-enhancing drugs: implications for drug side effects in humans. The Pharmacogenomics Journal. 13: 551-7. PMID 22964922 DOI: 10.1038/tpj.2012.35  0.683
2013 Moya PR, Wendland JR, Salemme J, Fried RL, Murphy DL. miR-15a and miR-16 regulate serotonin transporter expression in human placental and rat brain raphe cells. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 621-9. PMID 22564678 DOI: 10.1017/S1461145712000454  0.65
2012 Guiard BP, Mansari ME, Murphy DL, Blier P. Altered response to the selective serotonin reuptake inhibitor escitalopram in mice heterozygous for the serotonin transporter: an electrophysiological and neurochemical study. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 349-61. PMID 21439106 DOI: 10.1017/S1461145711000484  0.379
2012 Murphy DL. Serotonin neurochemistry: A commentary on some of its quandaries. Neurochemistry International. 8: 161-3. PMID 20493042 DOI: 10.1016/0197-0186(86)90159-2  0.342
2011 Hagino Y, Takamatsu Y, Yamamoto H, Iwamura T, Murphy DL, Uhl GR, Sora I, Ikeda K. Effects of MDMA on Extracellular Dopamine and Serotonin Levels in Mice Lacking Dopamine and/or Serotonin Transporters. Current Neuropharmacology. 9: 91-5. PMID 21886569 DOI: 10.2174/157015911795017254  0.348
2011 Timpano KR, Schmidt NB, Wheaton MG, Wendland JR, Murphy DL. Consideration of the BDNF gene in relation to two phenotypes: hoarding and obesity. Journal of Abnormal Psychology. 120: 700-7. PMID 21668081 DOI: 10.1037/A0024159  0.304
2011 Moya PR, Fox MA, Jensen CL, Laporte JL, French HT, Wendland JR, Murphy DL. Altered 5-HT2C receptor agonist-induced responses and 5-HT2C receptor RNA editing in the amygdala of serotonin transporter knockout mice. Bmc Pharmacology. 11: 3. PMID 21473759 DOI: 10.1186/1471-2210-11-3  0.702
2011 Murphy DL, Moya PR. Human serotonin transporter gene (SLC6A4) variants: their contributions to understanding pharmacogenomic and other functional G×G and G×E differences in health and disease. Current Opinion in Pharmacology. 11: 3-10. PMID 21439906 DOI: 10.1016/J.Coph.2011.02.008  0.716
2011 Mroczkowski MM, Goes FS, Riddle MA, Grados MA, Bienvenu OJ, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Knowles JA, Piacentini J, Cullen B, Rasmussen SA, Geller DA, et al. Separation anxiety disorder in OCD. Depression and Anxiety. 28: 256-62. PMID 21308883 DOI: 10.1002/Da.20773  0.313
2011 Hall FS, Schwarzbaum JM, Perona MT, Templin JS, Caron MG, Lesch KP, Murphy DL, Uhl GR. A greater role for the norepinephrine transporter than the serotonin transporter in murine nociception. Neuroscience. 175: 315-27. PMID 21129446 DOI: 10.1016/J.Neuroscience.2010.11.057  0.318
2011 Voyiaziakis E, Evgrafov O, Li D, Yoon HJ, Tabares P, Samuels J, Wang Y, Riddle MA, Grados MA, Bienvenu OJ, Shugart YY, Liang KY, Greenberg BD, Rasmussen SA, Murphy DL, et al. Association of SLC6A4 variants with obsessive-compulsive disorder in a large multicenter US family study. Molecular Psychiatry. 16: 108-20. PMID 19806148 DOI: 10.1038/Mp.2009.100  0.301
2010 Voon V, Butler TR, Ekanayake V, Gallea C, Ameli R, Murphy DL, Hallett M. Psychiatric symptoms associated with focal hand dystonia. Movement Disorders : Official Journal of the Movement Disorder Society. 25: 2249-52. PMID 20737548 DOI: 10.1002/Mds.23250  0.307
2010 Moya PR, Murphy DL, McMahon FJ, Wendland JR. Increased gene expression of diacylglycerol kinase η in bipolar disorder. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 13: 1127-8. PMID 20519059 DOI: 10.1017/S1461145710000593  0.684
2010 Fox MA, Stein AR, French HT, Murphy DL. Functional interactions between 5-HT2A and presynaptic 5-HT1A receptor-based responses in mice genetically deficient in the serotonin 5-HT transporter (SERT). British Journal of Pharmacology. 159: 879-87. PMID 20128812 DOI: 10.1111/J.1476-5381.2009.00578.X  0.342
2010 Brigman JL, Mathur P, Harvey-White J, Izquierdo A, Saksida LM, Bussey TJ, Fox S, Deneris E, Murphy DL, Holmes A. Pharmacological or genetic inactivation of the serotonin transporter improves reversal learning in mice. Cerebral Cortex (New York, N.Y. : 1991). 20: 1955-63. PMID 20032063 DOI: 10.1093/Cercor/Bhp266  0.362
2010 Fox MA, French HT, LaPorte JL, Blackler AR, Murphy DL. The serotonin 5-HT(2A) receptor agonist TCB-2: a behavioral and neurophysiological analysis. Psychopharmacology. 212: 13-23. PMID 19823806 DOI: 10.1007/S00213-009-1694-1  0.359
2009 Wendland JR, Moya PR, Timpano KR, Anavitarte AP, Kruse MR, Wheaton MG, Ren-Patterson RF, Murphy DL. A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder. Archives of General Psychiatry. 66: 408-16. PMID 19349310 DOI: 10.1001/Archgenpsychiatry.2009.6  0.68
2009 Fox MA, Jensen CL, Murphy DL. Tramadol and another atypical opioid meperidine have exaggerated serotonin syndrome behavioural effects, but decreased analgesic effects, in genetically deficient serotonin transporter (SERT) mice. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 1055-65. PMID 19275775 DOI: 10.1017/S146114570900011X  0.351
2009 Basselin M, Fox MA, Chang L, Bell JM, Greenstein D, Chen M, Murphy DL, Rapoport SI. Imaging elevated brain arachidonic acid signaling in unanesthetized serotonin transporter (5-HTT)-deficient mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1695-709. PMID 19145225 DOI: 10.1038/Npp.2008.227  0.359
2009 Timpano KR, Buckner JD, Richey JA, Murphy DL, Schmidt NB. Exploration of anxiety sensitivity and distress tolerance as vulnerability factors for hoarding behaviors. Depression and Anxiety. 26: 343-53. PMID 19123454 DOI: 10.1002/Da.20469  0.303
2009 Züchner S, Wendland JR, Ashley-Koch AE, Collins AL, Tran-Viet KN, Quinn K, Timpano KC, Cuccaro ML, Pericak-Vance MA, Steffens DC, Krishnan KR, Feng G, Murphy DL. Multiple rare SAPAP3 missense variants in trichotillomania and OCD. Molecular Psychiatry. 14: 6-9. PMID 19096451 DOI: 10.1038/Mp.2008.83  0.357
2009 Bienvenu OJ, Wang Y, Shugart YY, Welch JM, Grados MA, Fyer AJ, Rauch SL, McCracken JT, Rasmussen SA, Murphy DL, Cullen B, Valle D, Hoehn-Saric R, Greenberg BD, Pinto A, et al. Sapap3 and pathological grooming in humans: Results from the OCD collaborative genetics study. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 710-20. PMID 19051237 DOI: 10.1002/Ajmg.B.30897  0.326
2009 Nestadt G, Di CZ, Riddle MA, Grados MA, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Pinto A, Knowles JA, Piacentini J, Pauls DL, et al. Obsessive-compulsive disorder: subclassification based on co-morbidity. Psychological Medicine. 39: 1491-501. PMID 19046474 DOI: 10.1017/S0033291708004753  0.316
2009 Moy SS, Nadler JJ, Young NB, Nonneman RJ, Grossman AW, Murphy DL, D'Ercole AJ, Crawley JN, Magnuson TR, Lauder JM. Social approach in genetically engineered mouse lines relevant to autism. Genes, Brain, and Behavior. 8: 129-42. PMID 19016890 DOI: 10.1111/J.1601-183X.2008.00452.X  0.311
2008 Liu L, Foroud T, Xuei X, Berrettini W, Byerley W, Coryell W, El-Mallakh R, Gershon ES, Kelsoe JR, Lawson WB, MacKinnon DF, McInnis M, McMahon FJ, Murphy DL, Rice J, et al. Evidence of association between brain-derived neurotrophic factor gene and bipolar disorder. Psychiatric Genetics. 18: 267-74. PMID 19018231 DOI: 10.1097/Ypg.0B013E3283060F59  0.319
2008 Murphy DL, Fox MA, Timpano KR, Moya PR, Ren-Patterson R, Andrews AM, Holmes A, Lesch KP, Wendland JR. How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems. Neuropharmacology. 55: 932-60. PMID 18824000 DOI: 10.1016/J.Neuropharm.2008.08.034  0.751
2008 Fox MA, Jensen CL, French HT, Stein AR, Huang SJ, Tolliver TJ, Murphy DL. Neurochemical, behavioral, and physiological effects of pharmacologically enhanced serotonin levels in serotonin transporter (SERT)-deficient mice. Psychopharmacology. 201: 203-18. PMID 18712364 DOI: 10.1007/S00213-008-1268-7  0.375
2008 Perona MT, Waters S, Hall FS, Sora I, Lesch KP, Murphy DL, Caron M, Uhl GR. Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: prominent effects of dopamine transporter deletions. Behavioural Pharmacology. 19: 566-74. PMID 18690111 DOI: 10.1097/Fbp.0B013E32830Cd80F  0.352
2008 Laporte JL, Ren-Patterson RF, Murphy DL, Kalueff AV. Refining psychiatric genetics: from 'mouse psychiatry' to understanding complex human disorders. Behavioural Pharmacology. 19: 377-84. PMID 18690099 DOI: 10.1097/Fbp.0B013E32830Dc09B  0.307
2008 Ross J, Berrettini W, Coryell W, Gershon ES, Badner JA, Kelsoe JR, McInnis MG, McMahon FJ, Murphy DL, Nurnberger JI, Foroud T, Rice JP, Scheftner WB, Zandi P, Edenberg H, et al. Genome-wide parametric linkage analyses of 644 bipolar pedigrees suggest susceptibility loci at chromosomes 16 and 20. Psychiatric Genetics. 18: 191-8. PMID 18628681 DOI: 10.1097/Ypg.0B013E3283050Aa5  0.305
2008 Carneiro AM, Cook EH, Murphy DL, Blakely RD. Interactions between integrin alphaIIbbeta3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans. The Journal of Clinical Investigation. 118: 1544-52. PMID 18317590 DOI: 10.1172/Jci33374  0.358
2008 Murphy DL, Lesch KP. Targeting the murine serotonin transporter: insights into human neurobiology. Nature Reviews. Neuroscience. 9: 85-96. PMID 18209729 DOI: 10.1038/Nrn2284  0.343
2008 Wendland JR, DeGuzman TB, McMahon F, Rudnick G, Detera-Wadleigh SD, Murphy DL. SERT Ileu425Val in autism, Asperger syndrome and obsessive-compulsive disorder. Psychiatric Genetics. 18: 31-9. PMID 18197083 DOI: 10.1097/Ypg.0B013E3282F08A06  0.341
2008 Kalueff AV, Ren-Patterson RF, LaPorte JL, Murphy DL. Domain interplay concept in animal models of neuropsychiatric disorders: a new strategy for high-throughput neurophenotyping research. Behavioural Brain Research. 188: 243-9. PMID 18164476 DOI: 10.1016/J.Bbr.2007.11.011  0.32
2008 Wendland JR, Moya PR, Kruse MR, Ren-Patterson RF, Jensen CL, Timpano KR, Murphy DL. A novel, putative gain-of-function haplotype at SLC6A4 associates with obsessive-compulsive disorder. Human Molecular Genetics. 17: 717-23. PMID 18055562 DOI: 10.1093/Hmg/Ddm343  0.695
2008 Kalueff AV, LaPorte JL, Murphy DL. Perspectives on genetic animal models of serotonin toxicity. Neurochemistry International. 52: 649-58. PMID 17935833 DOI: 10.1016/J.Neuint.2007.08.015  0.353
2008 Wheaton M, Timpano KR, LaSalle-Ricci VH, Murphy D. Characterizing the hoarding phenotype in individuals with OCD: Associations with comorbidity, severity and gender Journal of Anxiety Disorders. 22: 243-252. PMID 17339096 DOI: 10.1016/J.Janxdis.2007.01.015  0.325
2007 Kalueff AV, Murphy DL. The importance of cognitive phenotypes in experimental modeling of animal anxiety and depression. Neural Plasticity. 2007: 52087. PMID 18288249 DOI: 10.1155/2007/52087  0.315
2007 Fox MA, Jensen CL, Gallagher PS, Murphy DL. Receptor mediation of exaggerated responses to serotonin-enhancing drugs in serotonin transporter (SERT)-deficient mice. Neuropharmacology. 53: 643-56. PMID 17765930 DOI: 10.1016/J.Neuropharm.2007.07.009  0.352
2007 Fox MA, Andrews AM, Wendland JR, Lesch KP, Holmes A, Murphy DL. A pharmacological analysis of mice with a targeted disruption of the serotonin transporter. Psychopharmacology. 195: 147-66. PMID 17712549 DOI: 10.1007/S00213-007-0910-0  0.557
2007 Kalueff AV, Jensen CL, Murphy DL. Locomotory patterns, spatiotemporal organization of exploration and spatial memory in serotonin transporter knockout mice. Brain Research. 1169: 87-97. PMID 17692295 DOI: 10.1016/J.Brainres.2007.07.009  0.323
2007 Numachi Y, Ohara A, Yamashita M, Fukushima S, Kobayashi H, Hata H, Watanabe H, Hall FS, Lesch KP, Murphy DL, Uhl GR, Sora I. Methamphetamine-induced hyperthermia and lethal toxicity: role of the dopamine and serotonin transporters. European Journal of Pharmacology. 572: 120-8. PMID 17673199 DOI: 10.1016/J.Ejphar.2007.06.022  0.314
2007 Cromer KR, Schmidt NB, Murphy DL. Do traumatic events influence the clinical expression of compulsive hoarding? Behaviour Research and Therapy. 45: 2581-92. PMID 17673166 DOI: 10.1016/J.Brat.2007.06.005  0.307
2007 Schmitt A, Benninghoff J, Moessner R, Rizzi M, Paizanis E, Doenitz C, Gross S, Hermann M, Gritti A, Lanfumey L, Fritzen S, Reif A, Hamon M, Murphy DL, Vescovi A, et al. Adult neurogenesis in serotonin transporter deficient mice. Journal of Neural Transmission (Vienna, Austria : 1996). 114: 1107-19. PMID 17510734 DOI: 10.1007/S00702-007-0724-6  0.338
2007 Grados MA, Samuels J, Shugart YY, Willour VL, Wang Y, Cullen B, Bienvenu OJ, Hoehn-Saric R, Valle D, Liang KY, Riddle MA, Wendland JR, Murphy DL, Nestadt G, Detera-Wadleigh S. Rare plus common SERT variants in obsessive-compulsive disorder. Molecular Psychiatry. 12: 422-3. PMID 17453059 DOI: 10.1038/Sj.Mp.4001970  0.317
2007 Wendland JR, Kruse MR, Cromer KR, Cromer KC, Murphy DL. A large case-control study of common functional SLC6A4 and BDNF variants in obsessive-compulsive disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 2543-51. PMID 17375136 DOI: 10.1038/Sj.Npp.1301394  0.352
2007 Kalueff AV, Wheaton M, Murphy DL. What's wrong with my mouse model? Advances and strategies in animal modeling of anxiety and depression. Behavioural Brain Research. 179: 1-18. PMID 17306892 DOI: 10.1016/J.Bbr.2007.01.023  0.304
2007 Kalueff AV, Ren-Patterson RF, Murphy DL. The developing use of heterozygous mutant mouse models in brain monoamine transporter research. Trends in Pharmacological Sciences. 28: 122-7. PMID 17275930 DOI: 10.1016/J.Tips.2007.01.002  0.354
2007 Goes FS, Zandi PP, Miao K, McMahon FJ, Steele J, Willour VL, Mackinnon DF, Mondimore FM, Schweizer B, Nurnberger JI, Rice JP, Scheftner W, Coryell W, Berrettini WH, Kelsoe JR, ... ... Murphy DL, et al. Mood-incongruent psychotic features in bipolar disorder: familial aggregation and suggestive linkage to 2p11-q14 and 13q21-33. The American Journal of Psychiatry. 164: 236-47. PMID 17267786 DOI: 10.1176/Ajp.2007.164.2.236  0.306
2007 Carroll JC, Boyce-Rustay JM, Millstein R, Yang R, Wiedholz LM, Murphy DL, Holmes A. Effects of mild early life stress on abnormal emotion-related behaviors in 5-HTT knockout mice. Behavior Genetics. 37: 214-22. PMID 17177116 DOI: 10.1007/S10519-006-9129-9  0.317
2007 Kalueff AV, Fox MA, Gallagher PS, Murphy DL. Hypolocomotion, anxiety and serotonin syndrome-like behavior contribute to the complex phenotype of serotonin transporter knockout mice. Genes, Brain, and Behavior. 6: 389-400. PMID 16939636 DOI: 10.1111/J.1601-183X.2006.00270.X  0.336
2007 Altamura C, Dell'Acqua ML, Moessner R, Murphy DL, Lesch KP, Persico AM. Altered neocortical cell density and layer thickness in serotonin transporter knockout mice: a quantitation study. Cerebral Cortex (New York, N.Y. : 1991). 17: 1394-401. PMID 16905592 DOI: 10.1093/Cercor/Bhl051  0.326
2007 Samuels JF, Bienvenu OJ, Pinto A, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Grados MA, Greenberg BD, Knowles JA, Piacentini J, Cannistraro PA, Cullen B, Riddle MA, Rasmussen SA, et al. Hoarding in obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study. Behaviour Research and Therapy. 45: 673-86. PMID 16824483 DOI: 10.1016/J.Brat.2006.05.008  0.326
2006 Boyce-Rustay JM, Wiedholz LM, Millstein RA, Carroll J, Murphy DL, Daws LC, Holmes A. Ethanol-related behaviors in serotonin transporter knockout mice. Alcoholism, Clinical and Experimental Research. 30: 1957-65. PMID 17117959 DOI: 10.1111/J.1530-0277.2006.00241.X  0.351
2006 Ren-Patterson RF, Cochran LW, Holmes A, Lesch KP, Lu B, Murphy DL. Gender-dependent modulation of brain monoamines and anxiety-like behaviors in mice with genetic serotonin transporter and BDNF deficiencies. Cellular and Molecular Neurobiology. 26: 755-80. PMID 17029036 DOI: 10.1007/S10571-006-9048-6  0.348
2006 Kalueff AV, Gallagher PS, Murphy DL. Are serotonin transporter knockout mice 'depressed'?: hypoactivity but no anhedonia. Neuroreport. 17: 1347-51. PMID 16951583 DOI: 10.1097/01.Wnr.0000230514.08962.76  0.329
2006 Hu XZ, Lipsky RH, Zhu G, Akhtar LA, Taubman J, Greenberg BD, Xu K, Arnold PD, Richter MA, Kennedy JL, Murphy DL, Goldman D. Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. American Journal of Human Genetics. 78: 815-26. PMID 16642437 DOI: 10.1086/503850  0.3
2006 Hasler G, Kazuba D, Murphy DL. Factor analysis of obsessive-compulsive disorder YBOCS-SC symptoms and association with 5-HTTLPR SERT polymorphism. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 403-8. PMID 16583440 DOI: 10.1002/Ajmg.B.30309  0.305
2006 Adamec R, Burton P, Blundell J, Murphy DL, Holmes A. Vulnerability to mild predator stress in serotonin transporter knockout mice. Behavioural Brain Research. 170: 126-40. PMID 16546269 DOI: 10.1016/J.Bbr.2006.02.012  0.347
2006 Zhao S, Edwards J, Carroll J, Wiedholz L, Millstein RA, Jaing C, Murphy DL, Lanthorn TH, Holmes A. Insertion mutation at the C-terminus of the serotonin transporter disrupts brain serotonin function and emotion-related behaviors in mice. Neuroscience. 140: 321-34. PMID 16542782 DOI: 10.1016/J.Neuroscience.2006.01.049  0.376
2006 Samuels JF, Riddle MA, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Grados MA, Pinto A, Knowles JA, Piacentini J, Cannistraro PA, Cullen B, Bienvenu OJ, Rasmussen SA, et al. The OCD collaborative genetics study: methods and sample description. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 201-7. PMID 16511842 DOI: 10.1002/Ajmg.B.30224  0.32
2006 Ichise M, Cannon D, Klaver J, Sangare J, Murphy D, Innis R. [11C]DASB PET imaging of serotonin transporters in unmedicated patients with early onset obsessive compulsive disorder Neuroimage. 31: T167. DOI: 10.1016/J.Neuroimage.2006.04.150  0.314
2005 Kim DK, Tolliver TJ, Huang SJ, Martin BJ, Andrews AM, Wichems C, Holmes A, Lesch KP, Murphy DL. Altered serotonin synthesis, turnover and dynamic regulation in multiple brain regions of mice lacking the serotonin transporter. Neuropharmacology. 49: 798-810. PMID 16183083 DOI: 10.1016/J.Neuropharm.2005.08.010  0.557
2005 Ren-Patterson RF, Kim DK, Zheng X, Sherrill S, Huang SJ, Tolliver T, Murphy DL. Serotonergic-like progenitor cells propagated from neural stem cells in vitro: survival with SERT protein expression following implantation into brains of mice lacking SERT. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1537-9. PMID 15972295 DOI: 10.1096/Fj.04-3657Fje  0.317
2005 Ni W, Wilhelm CS, Bader M, Murphy DL, Lookingland K, Watts SW. (+)-Norfenfluramine-induced arterial contraction is not dependent on endogenous 5-hydroxytryptamine or 5-hydroxytryptamine transporter. The Journal of Pharmacology and Experimental Therapeutics. 314: 953-60. PMID 15901794 DOI: 10.1124/Jpet.105.087080  0.344
2005 Hasler G, LaSalle-Ricci VH, Ronquillo JG, Crawley SA, Cochran LW, Kazuba D, Greenberg BD, Murphy DL. Obsessive-compulsive disorder symptom dimensions show specific relationships to psychiatric comorbidity. Psychiatry Research. 135: 121-32. PMID 15893825 DOI: 10.1016/J.Psychres.2005.03.003  0.309
2005 Qu Y, Villacreses N, Murphy DL, Rapoport SI. 5-HT2A/2C receptor signaling via phospholipase A2 and arachidonic acid is attenuated in mice lacking the serotonin reuptake transporter. Psychopharmacology. 180: 12-20. PMID 15834538 DOI: 10.1007/S00213-005-2231-5  0.332
2005 Esaki T, Cook M, Shimoji K, Murphy DL, Sokoloff L, Holmes A. Developmental disruption of serotonin transporter function impairs cerebral responses to whisker stimulation in mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 5582-7. PMID 15809439 DOI: 10.1073/Pnas.0501509102  0.358
2005 Ren-Patterson RF, Cochran LW, Holmes A, Sherrill S, Huang SJ, Tolliver T, Lesch KP, Lu B, Murphy DL. Loss of brain-derived neurotrophic factor gene allele exacerbates brain monoamine deficiencies and increases stress abnormalities of serotonin transporter knockout mice. Journal of Neuroscience Research. 79: 756-71. PMID 15672416 DOI: 10.1002/Jnr.20410  0.354
2004 Mathews TA, Fedele DE, Coppelli FM, Avila AM, Murphy DL, Andrews AM. Gene dose-dependent alterations in extraneuronal serotonin but not dopamine in mice with reduced serotonin transporter expression. Journal of Neuroscience Methods. 140: 169-81. PMID 15589347 DOI: 10.1016/J.Jneumeth.2004.05.017  0.578
2004 Li Q, Holmes A, Ma L, Van de Kar LD, Garcia F, Murphy DL. Medial hypothalamic 5-hydroxytryptamine (5-HT)1A receptors regulate neuroendocrine responses to stress and exploratory locomotor activity: application of recombinant adenovirus containing 5-HT1A sequences. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10868-77. PMID 15574737 DOI: 10.1523/Jneurosci.3223-04.2004  0.334
2004 Cichon S, Buervenich S, Kirov G, Akula N, Dimitrova A, Green E, Schumacher J, Klopp N, Becker T, Ohlraun S, Schulze TG, Tullius M, Gross MM, Jones L, Krastev S, ... ... Murphy DL, et al. Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin. Nature Genetics. 36: 783-4; author reply . PMID 15284840 DOI: 10.1038/Ng0804-783  0.307
2004 Tjurmina OA, Armando I, Saavedra JM, Li Q, Murphy DL. Life-long serotonin reuptake deficiency results in complex alterations in adrenomedullary responses to stress. Annals of the New York Academy of Sciences. 1018: 99-104. PMID 15240357 DOI: 10.1196/Annals.1296.011  0.335
2004 Shen HW, Hagino Y, Kobayashi H, Shinohara-Tanaka K, Ikeda K, Yamamoto H, Yamamoto T, Lesch KP, Murphy DL, Hall FS, Uhl GR, Sora I. Regional differences in extracellular dopamine and serotonin assessed by in vivo microdialysis in mice lacking dopamine and/or serotonin transporters. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1790-9. PMID 15226739 DOI: 10.1038/Sj.Npp.1300476  0.306
2004 Murphy DL, Lerner A, Rudnick G, Lesch KP. Serotonin transporter: gene, genetic disorders, and pharmacogenetics. Molecular Interventions. 4: 109-23. PMID 15087484 DOI: 10.1124/Mi.4.2.8  0.403
2004 Li Q, Ma L, Innis RB, Seneca N, Ichise M, Huang H, Laruelle M, Murphy DL. Pharmacological and genetic characterization of two selective serotonin transporter ligands: 2-[2-(dimethylaminomethylphenylthio)]-5-fluoromethylphenylamine (AFM) and 3-amino-4-[2-(dimethylaminomethyl-phenylthio)]benzonitrile (DASB). The Journal of Pharmacology and Experimental Therapeutics. 308: 481-6. PMID 14610240 DOI: 10.1124/Jpet.103.058636  0.356
2003 Holmes A, Lit Q, Murphy DL, Gold E, Crawley JN. Abnormal anxiety-related behavior in serotonin transporter null mutant mice: the influence of genetic background. Genes, Brain, and Behavior. 2: 365-80. PMID 14653308 DOI: 10.1046/J.1601-1848.2003.00050.X  0.354
2003 Holmes A, Murphy DL, Crawley JN. Abnormal behavioral phenotypes of serotonin transporter knockout mice: parallels with human anxiety and depression. Biological Psychiatry. 54: 953-9. PMID 14625137 DOI: 10.1016/J.Biopsych.2003.09.003  0.379
2003 Ozaki N, Goldman D, Kaye WH, Plotnicov K, Greenberg BD, Lappalainen J, Rudnick G, Murphy DL. Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype. Molecular Psychiatry. 8: 933-6. PMID 14593431 DOI: 10.1038/Sj.Mp.4001365  0.347
2003 Armando I, Tjurmina OA, Li Q, Murphy DL, Saavedra JM. The serotonin transporter is required for stress-evoked increases in adrenal catecholamine synthesis and angiotensin II AT(2) receptor expression. Neuroendocrinology. 78: 217-25. PMID 14583654 DOI: 10.1159/000073705  0.333
2003 Luellen BA, Miller DB, Chisnell AC, Murphy DL, O'Callaghan JP, Andrews AM. Neuronal and astroglial responses to the serotonin and norepinephrine neurotoxin: 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine. The Journal of Pharmacology and Experimental Therapeutics. 307: 923-31. PMID 14561848 DOI: 10.1124/Jpet.103.055749  0.551
2003 Kilic F, Murphy DL, Rudnick G. A human serotonin transporter mutation causes constitutive activation of transport activity. Molecular Pharmacology. 64: 440-6. PMID 12869649 DOI: 10.1124/Mol.64.2.440  0.313
2003 Montañez S, Owens WA, Gould GG, Murphy DL, Daws LC. Exaggerated effect of fluvoxamine in heterozygote serotonin transporter knockout mice. Journal of Neurochemistry. 86: 210-9. PMID 12807440 DOI: 10.1046/J.1471-4159.2003.01836.X  0.355
2003 Persico AM, Baldi A, Dell'Acqua ML, Moessner R, Murphy DL, Lesch KP, Keller F. Reduced programmed cell death in brains of serotonin transporter knockout mice. Neuroreport. 14: 341-4. PMID 12634480 DOI: 10.1097/00001756-200303030-00009  0.332
2003 Li Q, Wichems CH, Ma L, Van de Kar LD, Garcia F, Murphy DL. Brain region-specific alterations of 5-HT2A and 5-HT2C receptors in serotonin transporter knockout mice. Journal of Neurochemistry. 84: 1256-65. PMID 12614326 DOI: 10.1046/J.1471-4159.2003.01607.X  0.341
2003 Schmitt A, Mössner R, Gossmann A, Fischer IG, Gorboulev V, Murphy DL, Koepsell H, Lesch KP. Organic cation transporter capable of transporting serotonin is up-regulated in serotonin transporter-deficient mice. Journal of Neuroscience Research. 71: 701-9. PMID 12584728 DOI: 10.1002/Jnr.10521  0.363
2003 Vogel C, Mössner R, Gerlach M, Heinemann T, Murphy DL, Riederer P, Lesch KP, Sommer C. Absence of thermal hyperalgesia in serotonin transporter-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 708-15. PMID 12533631 DOI: 10.1523/Jneurosci.23-02-00708.2003  0.33
2002 Holmes A, Yang RJ, Murphy DL, Crawley JN. Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 914-23. PMID 12464448 DOI: 10.1016/S0893-133X(02)00374-3  0.336
2002 Tjurmina OA, Armando I, Saavedra JM, Goldstein DS, Murphy DL. Exaggerated adrenomedullary response to immobilization in mice with targeted disruption of the serotonin transporter gene. Endocrinology. 143: 4520-6. PMID 12446578 DOI: 10.1210/En.2002-220416  0.359
2002 Roca CA, Schmidt PJ, Smith MJ, Danaceau MA, Murphy DL, Rubinow DR. Effects of metergoline on symptoms in women with premenstrual dysphoric disorder. The American Journal of Psychiatry. 159: 1876-81. PMID 12411222 DOI: 10.1176/Appi.Ajp.159.11.1876  0.31
2002 Unger EL, Mazzola-Pomietto P, Murphy DL, Andrews AM. 2'-NH(2)-MPTP [1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine] depletes serotonin and norepinephrine in rats: a comparison with 2'-CH(3)-MPTP [1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine]. The Journal of Pharmacology and Experimental Therapeutics. 303: 527-33. PMID 12388632 DOI: 10.1124/Jpet.102.037614  0.525
2002 Zhou FC, Lesch KP, Murphy DL. Serotonin uptake into dopamine neurons via dopamine transporters: a compensatory alternative. Brain Research. 942: 109-19. PMID 12031859 DOI: 10.1016/S0006-8993(02)02709-9  0.337
2002 Holmes A, Murphy DL, Crawley JN. Reduced aggression in mice lacking the serotonin transporter. Psychopharmacology. 161: 160-7. PMID 11981596 DOI: 10.1007/S00213-002-1024-3  0.345
2001 Meiri G, Ben-Zion IZ, Greenberg BD, Murphy DL, Benjamin J. Influence of the serotonin antagonist, metergoline, on the anxiogenic effects of carbon dioxide, and on heart rate and neuroendocrine measures, in healthy volunteers. Human Psychopharmacology. 16: 237-245. PMID 12404576 DOI: 10.1002/Hup.259  0.354
2001 Murphy DL, Li Q, Engel S, Wichems C, Andrews A, Lesch KP, Uhl G. Genetic perspectives on the serotonin transporter. Brain Research Bulletin. 56: 487-94. PMID 11750794 DOI: 10.1016/S0361-9230(01)00622-0  0.565
2001 Persico AM, Mengual E, Moessner R, Hall FS, Revay RS, Sora I, Arellano J, DeFelipe J, Gimenez-Amaya JM, Conciatori M, Marino R, Baldi A, Cabib S, Pascucci T, Uhl GR, ... Murphy DL, et al. Barrel pattern formation requires serotonin uptake by thalamocortical afferents, and not vesicular monoamine release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6862-73. PMID 11517274 DOI: 10.1523/Jneurosci.21-17-06862.2001  0.345
2001 Chen JJ, Li Z, Pan H, Murphy DL, Tamir H, Koepsell H, Gershon MD. Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6348-61. PMID 11487658 DOI: 10.1523/Jneurosci.21-16-06348.2001  0.361
2001 Sora I, Hall FS, Andrews AM, Itokawa M, Li XF, Wei HB, Wichems C, Lesch KP, Murphy DL, Uhl GR. Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. Proceedings of the National Academy of Sciences of the United States of America. 98: 5300-5. PMID 11320258 DOI: 10.1073/Pnas.091039298  0.492
2001 Ravary A, Muzerelle A, Darmon M, Murphy DL, Moessner R, Lesch KP, Gaspar P. Abnormal trafficking and subcellular localization of an N-terminally truncated serotonin transporter protein. The European Journal of Neuroscience. 13: 1349-62. PMID 11298795 DOI: 10.1046/J.0953-816X.2001.1511.X  0.317
2001 Enoch MA, Greenberg BD, Murphy DL, Goldman D. Sexually dimorphic relationship of a 5-HT2A promoter polymorphism with obsessive-compulsive disorder. Biological Psychiatry. 49: 385-8. PMID 11239910 DOI: 10.1016/S0006-3223(00)01040-4  0.306
2001 Salichon N, Gaspar P, Upton AL, Picaud S, Hanoun N, Hamon M, Maeyer ED, Murphy DL, Mössner R, Lesch KP, Hen R, Seif I. Excessive activation of serotonin (5-HT) 1B receptors disrupts the formation of sensory maps in monoamine oxidase a and 5-ht transporter knock-out mice. The Journal of Neuroscience. 21: 884-896. DOI: 10.1523/Jneurosci.21-03-00884.2001  0.349
2000 Sher L, Greenberg BD, Murphy DL, Rosenthal NE, Sirota LA, Hamer DH. Pleiotropy of the serotonin transporter gene for seasonality and neuroticism. Psychiatric Genetics. 10: 125-30. PMID 11204348 DOI: 10.1097/00041444-200010030-00004  0.321
2000 Li Q, Wichems C, Heils A, Lesch KP, Murphy DL. Reduction in the density and expression, but not G-protein coupling, of serotonin receptors (5-HT1A) in 5-HT transporter knock-out mice: gender and brain region differences. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7888-95. PMID 11050108 DOI: 10.1523/Jneurosci.20-21-07888.2000  0.329
2000 Greenberg BD, Murphy DL, Rasmussen SA. Neuroanatomically based approaches to obsessive-compulsive disorder. Neurosurgery and transcranial magnetic stimulation. The Psychiatric Clinics of North America. 23: 671-86, xii. PMID 10986735 DOI: 10.1016/S0193-953X(05)70188-X  0.304
2000 Fabre V, Beaufour C, Evrard A, Rioux A, Hanoun N, Lesch KP, Murphy DL, Lanfumey L, Hamon M, Martres MP. Altered expression and functions of serotonin 5-HT1A and 5-HT1B receptors in knock-out mice lacking the 5-HT transporter. The European Journal of Neuroscience. 12: 2299-310. PMID 10947809 DOI: 10.1046/J.1460-9568.2000.00126.X  0.367
2000 Greenberg BD, Li Q, Lucas FR, Hu S, Sirota LA, Benjamin J, Lesch KP, Hamer D, Murphy DL. Association between the serotonin transporter promoter polymorphism and personality traits in a primarily female population sample. American Journal of Medical Genetics. 96: 202-16. PMID 10893498 DOI: 10.1002/(Sici)1096-8628(20000403)96:2<202::Aid-Ajmg16>3.0.Co;2-J  0.304
2000 Sher L, Hamer D, Greenberg B, Murphy D, Rosenthal N. 256. The serotonin transporter gene influences seasonality independently of personality Biological Psychiatry. 47: S78. DOI: 10.1016/S0006-3223(00)00520-5  0.301
1999 Hamer DH, Greenberg BD, Sabol SZ, Murphy DL. Role of the serotonin transporter gene in temperament and character. Journal of Personality Disorders. 13: 312-27. PMID 10633313 DOI: 10.1521/Pedi.1999.13.4.312  0.322
1999 McCann UD, Eligulashvili V, Mertl M, Murphy DL, Ricaurte GA. Altered neuroendocrine and behavioral responses to m-chlorophenylpiperazine in 3,4-methylenedioxymethamphetamine (MDMA) users. Psychopharmacology. 147: 56-65. PMID 10591869 DOI: 10.1007/S002130051142  0.346
1999 Ben-Zion IZ, Meiri G, Greenberg BD, Murphy DL, Benjamin J. Enhancement of CO2-induced anxiety in healthy volunteers with the serotonin antagonist metergoline. The American Journal of Psychiatry. 156: 1635-7. PMID 10518177 DOI: 10.1176/Ajp.156.10.1635  0.327
1999 Altemus M, Greenberg BD, Keuler D, Jacobson KR, Murphy DL. Open trial of flutamide for treatment of obsessive-compulsive disorder. The Journal of Clinical Psychiatry. 60: 442-5. PMID 10453797 DOI: 10.4088/Jcp.V60N0704  0.316
1999 Murphy DL, Wichems C, Li Q, Heils A. Molecular manipulations as tools for enhancing our understanding of 5-HT neurotransmission. Trends in Pharmacological Sciences. 20: 246-52. PMID 10366867 DOI: 10.1016/S0165-6147(99)01325-5  0.365
1999 Schwartz PJ, Turner EH, Garcia-Borreguero D, Sedway J, Vetticad RG, Wehr TA, Murphy DL, Rosenthal NE. Serotonin hypothesis of winter depression: behavioral and neuroendocrine effects of the 5-HT(1A) receptor partial agonist ipsapirone in patients with seasonal affective disorder and healthy control subjects. Psychiatry Research. 86: 9-28. PMID 10359479 DOI: 10.1016/S0165-1781(99)00017-7  0.398
1999 Rioux A, Fabre V, Lesch KP, Moessner R, Murphy DL, Lanfumey L, Hamon M, Martres MP. Adaptive changes of serotonin 5-HT2A receptors in mice lacking the serotonin transporter. Neuroscience Letters. 262: 113-6. PMID 10203244 DOI: 10.1016/S0304-3940(99)00049-X  0.336
1999 Han L, Nielsen DA, Rosenthal NE, Jefferson K, Kaye W, Murphy D, Altemus M, Humphries J, Cassano G, Rotondo A, Virkkunen M, Linnoila M, Goldman D. No coding variant of the tryptophan hydroxylase gene detected in seasonal affective disorder, obsessive-compulsive disorder, anorexia nervosa, and alcoholism. Biological Psychiatry. 45: 615-9. PMID 10088048 DOI: 10.1016/S0006-3223(98)00122-X  0.318
1999 Greenberg BD, Tolliver TJ, Huang SJ, Li Q, Bengel D, Murphy DL. Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets. American Journal of Medical Genetics. 88: 83-7. PMID 10050973 DOI: 10.1002/(Sici)1096-8628(19990205)88:1<83::Aid-Ajmg15>3.0.Co;2-0  0.377
1998 Greenberg BD, Benjamin J, Martin JD, Keuler D, Huang SJ, Altemus M, Murphy DL. Delayed obsessive-compulsive disorder symptom exacerbation after a single dose of a serotonin antagonist in fluoxetine-treated but not untreated patients. Psychopharmacology. 140: 434-44. PMID 9888619 DOI: 10.1007/S002130050787  0.373
1998 Murphy DL, Andrews AM, Wichems CH, Li Q, Tohda M, Greenberg B. Brain serotonin neurotransmission: an overview and update with an emphasis on serotonin subsystem heterogeneity, multiple receptors, interactions with other neurotransmitter systems, and consequent implications for understanding the actions of serotonergic drugs. The Journal of Clinical Psychiatry. 59: 4-12. PMID 9786305  0.503
1998 Corá-Locatelli G, Greenberg BD, Martin J, Murphy DL. Gabapentin augmentation for fluoxetine-treated patients with obsessive-compulsive disorder. The Journal of Clinical Psychiatry. 59: 480-1. PMID 9771822 DOI: 10.4088/Jcp.V59N0907D  0.325
1998 Broocks A, Pigott TA, Hill JL, Canter S, Grady TA, L'Heureux F, Murphy DL. Acute intravenous administration of ondansetron and m-CPP, alone and in combination, in patients with obsessive-compulsive disorder (OCD): behavioral and biological results. Psychiatry Research. 79: 11-20. PMID 9676822 DOI: 10.1016/S0165-1781(98)00029-8  0.386
1998 Bengel D, Murphy DL, Andrews AM, Wichems CH, Feltner D, Heils A, Mössner R, Westphal H, Lesch KP. Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4-methylenedioxymethamphetamine ("Ecstasy") in serotonin transporter-deficient mice. Molecular Pharmacology. 53: 649-55. PMID 9547354 DOI: 10.1124/Mol.53.4.649  0.516
1998 Broocks A, Little JT, Martin A, Minichiello MD, Dubbert B, Mack C, Tune L, Murphy DL, Sunderland T. The influence of ondansetron and m-chlorophenylpiperazine on scopolamine-induced cognitive, behavioral, and physiological responses in young healthy controls. Biological Psychiatry. 43: 408-16. PMID 9532345 DOI: 10.1016/S0006-3223(97)00388-0  0.308
1998 Lenders JW, Brunner HG, Murphy DL, Eisenhofer G. Genetic deficiencies of monoamine oxidase enzymes: a key to understanding the function of the enzymes in humans. Advances in Pharmacology (San Diego, Calif.). 42: 297-301. PMID 9327899 DOI: 10.1016/S1054-3589(08)60748-6  0.327
1997 Bengel D, Jöhren O, Andrews AM, Heils A, Mössner R, Sanvitto GL, Saavedra JM, Lesch KP, Murphy DL. Cellular localization and expression of the serotonin transporter in mouse brain. Brain Research. 778: 338-45. PMID 9459551 DOI: 10.1016/S0006-8993(97)01080-9  0.523
1997 McCann UD, Morgan CM, Geraci M, Slate SO, Murphy DL, Post RM. Effects of the 5-HT3 antagonist, ondansetron, on the behavioral and physiological effects of pentagastrin in patients with panic disorder and social phobia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 17: 360-9. PMID 9397424 DOI: 10.1016/S0893-133X(97)00085-7  0.388
1997 Karayiorgou M, Altemus M, Galke BL, Goldman D, Murphy DL, Ott J, Gogos JA. Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder. Proceedings of the National Academy of Sciences of the United States of America. 94: 4572-5. PMID 9114031 DOI: 10.1073/Pnas.94.9.4572  0.324
1997 Schwartz PJ, Murphy DL, Wehr TA, Garcia-Borreguero D, Oren DA, Moul DE, Ozaki N, Snelbaker AJ, Rosenthal NE. Effects of meta-chlorophenylpiperazine infusions in patients with seasonal affective disorder and healthy control subjects. Diurnal responses and nocturnal regulatory mechanisms. Archives of General Psychiatry. 54: 375-85. PMID 9107154 DOI: 10.1001/Archpsyc.1997.01830160103013  0.362
1997 Broocks A, Briggs NC, Pigott TA, Hill JL, Canter SK, Tolliver TJ, Baldemore D, Murphy DL. Behavioral, physiological and neuroendocrine responses in healthy volunteers to m-chlorophenylpiperazine (m-CPP) with and without ondansetron pretreatment. Psychopharmacology. 130: 91-103. PMID 9106905 DOI: 10.1007/S002130050215  0.339
1997 Bengel D, Heils A, Petri S, Seemann M, Glatz K, Andrews A, Murphy DL, Lesch KP. Gene structure and 5'-flanking regulatory region of the murine serotonin transporter. Brain Research. Molecular Brain Research. 44: 286-92. PMID 9073170 DOI: 10.1016/S0169-328X(96)00234-3  0.549
1997 Aulakh CS, Mazzola-Pomietto P, Murphy DL. Long-term antidepressant treatment restores clonidine's effect on growth hormone secretion in a genetic animal model of depression. Pharmacology, Biochemistry, and Behavior. 55: 265-8. PMID 8951963 DOI: 10.1016/S0091-3057(96)00080-9  0.319
1997 Greenberg BD, Altemus M, Murphy DL. The role of neurotransmitters and neurohormones in obsessive-compulsive disorder International Review of Psychiatry. 9: 31-44. DOI: 10.1080/09540269775574  0.39
1996 Andrews AM, Ladenheim B, Epstein CJ, Cadet JL, Murphy DL. Transgenic mice with high levels of superoxide dismutase activity are protected from the neurotoxic effects of 2'-NH2-MPTP on serotonergic and noradrenergic nerve terminals. Molecular Pharmacology. 50: 1511-9. PMID 8967972  0.502
1996 Lesch KP, Bengel D, Heils A, Sabol SZ, Greenberg BD, Petri S, Benjamin J, Müller CR, Hamer DH, Murphy DL. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science (New York, N.Y.). 274: 1527-31. PMID 8929413 DOI: 10.1126/Science.274.5292.1527  0.376
1996 Benjamin J, Greenberg BD, Murphy DL. Daily administration of m-chlorophenylpiperazine to healthy human volunteers rapidly attenuates many of its behavioral, hormonal, cardiovascular and temperature effects. Psychopharmacology. 127: 140-9. PMID 8888380 DOI: 10.1007/Bf02805987  0.35
1996 Grady TA, Broocks A, Canter SK, Pigott TA, Dubbert B, Hill JL, Murphy DL. Biological and behavioral responses to D-amphetamine, alone and in combination with the serotonin3 receptor antagonist ondansetron, in healthy volunteers. Psychiatry Research. 64: 1-10. PMID 8888359 DOI: 10.1016/0165-1781(96)02884-3  0.347
1996 Mazzola-Pomietto P, Aulakh CS, Wozniak KM, Murphy DL. Evidence that m-chlorophenylpiperazine-induced hyperthermia in rats is mediated by stimulation of 5-HT2C receptors. Psychopharmacology. 123: 333-9. PMID 8867872 DOI: 10.1007/Bf02246643  0.311
1996 Altemus M, Murphy DL, Greenberg B, Lesch KP. Intact coding region of the serotonin transporter gene in obsessive-compulsive disorder. American Journal of Medical Genetics. 67: 409-11. PMID 8837711 DOI: 10.1002/(Sici)1096-8628(19960726)67:4<409::Aid-Ajmg16>3.0.Co;2-N  0.363
1996 Keuler DJ, Altemus M, Michelson D, Greenberg B, Murphy DL. Behavioral effects of naloxone infusion in obsessive-compulsive disorder. Biological Psychiatry. 40: 154-6. PMID 8793049 DOI: 10.1016/0006-3223(95)00632-X  0.312
1996 Bonson KR, Murphy DL. Alterations in responses to LSD in humans associated with chronic administration of tricyclic antidepressants, monoamine oxidase inhibitors or lithium. Behavioural Brain Research. 73: 229-33. PMID 8788508 DOI: 10.1016/0166-4328(96)00102-7  0.331
1996 Murphy DL, Aulakh C, Mazzola-Pomietto P, Briggs NC. Neuroendocrine responses to serotonergic agonists as indices of the functional status of central serotonin neurotransmission in humans: a preliminary comparative analysis of neuroendocrine endpoints versus other endpoint measures. Behavioural Brain Research. 73: 209-14. PMID 8788504 DOI: 10.1016/0166-4328(96)00098-8  0.346
1996 Bonson KR, Buckholtz JW, Murphy DL. Chronic administration of serotonergic antidepressants attenuates the subjective effects of LSD in humans Neuropsychopharmacology. 14: 425-436. PMID 8726753 DOI: 10.1016/0893-133X(95)00145-4  0.364
1996 Mazzola-Pomietto P, Aulakh CS, Murphy DL. Temperature, food intake, and locomotor activity effects of a 5-HT3 receptor agonist and two 5-HT3 receptor antagonists in rats. Psychopharmacology. 121: 488-93. PMID 8619014 DOI: 10.1007/Bf02246499  0.312
1996 Benjamin J, Li L, Patterson C, Greenberg BD, Murphy DL, Hamer DH. Population and familial association between the D4 dopamine receptor gene and measures of Novelty Seeking. Nature Genetics. 12: 81-4. PMID 8528258 DOI: 10.1038/Ng0196-81  0.305
1995 Little JT, Broocks A, Martin A, Hill JL, Tune LE, Mack C, Cantillon M, Molchan S, Murphy DL, Sunderland T. Serotonergic modulation of anticholinergic effects on cognition and behavior in elderly humans. Psychopharmacology. 120: 280-8. PMID 8524975 DOI: 10.1007/Bf02311175  0.322
1995 Mazzola-Pomietto P, Aulakh CS, Wozniak KM, Hill JL, Murphy DL. Evidence that 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-induced hyperthermia in rats is mediated by stimulation of 5-HT2A receptors. Psychopharmacology. 117: 193-9. PMID 7753967 DOI: 10.1007/Bf02245187  0.332
1995 Lesch KP, Gross J, Franzek E, Wolozin BL, Riederer P, Murphy DL. Primary structure of the serotonin transporter in unipolar depression and bipolar disorder Biological Psychiatry. 37: 215-223. PMID 7711157 DOI: 10.1016/0006-3223(94)00147-U  0.384
1995 Garcia-Borreguero D, Jacobsen FM, Murphy DL, Joseph-Vanderpool JR, Chiara A, Rosenthal NE. Hormonal responses to the administration of m-chlorophenylpiperazine in patients with seasonal affective disorder and controls. Biological Psychiatry. 37: 740-9. PMID 7640329 DOI: 10.1016/0006-3223(94)00208-K  0.309
1995 Rubenstein CS, Altemus M, Pigott TA, Hess A, Murphy DL. Symptom overlap between OCD and bulimia nervosa Journal of Anxiety Disorders. 9: 1-9. DOI: 10.1016/0887-6185(95)91551-R  0.333
1994 Aulakh CS, Hill JL, Murphy DL. Attenuation of clonidine-induced growth hormone release following chronic glucocorticoid and 5-hydroxytryptamine uptake-inhibiting antidepressant treatments. Neuroendocrinology. 59: 35-41. PMID 8145893 DOI: 10.1159/000126635  0.329
1994 Aulakh CS, Hill JL, Murphy DL. Lithium treatment restores clonidine's effect in an animal model of depression. Pharmacology, Biochemistry, and Behavior. 47: 985-7. PMID 8029274 DOI: 10.1016/0091-3057(94)90308-5  0.306
1994 Jacobsen FM, Mueller EA, Rosenthal NE, Rogers S, Hill JL, Murphy DL. Behavioral responses to intravenous meta-chlorophenylpiperazine in patients with seasonal affective disorder and control subjects before and after phototherapy. Psychiatry Research. 52: 181-97. PMID 7972574 DOI: 10.1016/0165-1781(94)90087-6  0.345
1994 Brewerton TD, Murphy DL, Jimerson DC. Testmeal responses following m-chlorophenylpiperazine and L-tryptophan in bulimics and controls. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 11: 63-71. PMID 7945745 DOI: 10.1038/Npp.1994.36  0.309
1994 Lesch KP, Balling U, Gross J, Strauss K, Wolozin BL, Murphy DL, Riederer P. Organization of the human serotonin transporter gene Journal of Neural Transmission. 95: 157-162. PMID 7865169 DOI: 10.1007/Bf01276434  0.333
1994 Aulakh CS, Hill JL, Murphy DL. Enhanced anorexic responses to m-chlorophenylpiperazine during lithium administration to fawn-hooded rats. Pharmacology, Biochemistry, and Behavior. 49: 759-62. PMID 7862734 DOI: 10.1016/0091-3057(94)90098-1  0.311
1994 Ozaki N, Rosenthal NE, Mazzola P, Chiueh CC, Hardin T, Garcia-Borreguero D, Schwartz PJ, Turner E, Oren DA, Murphy DL. Platelet [3H]paroxetine binding, 5-HT-stimulated Ca2+ response, and 5-HT content in winter seasonal affective disorder. Biological Psychiatry. 36: 458-66. PMID 7811842 DOI: 10.1016/0006-3223(94)90641-6  0.347
1993 Brewerton TD, Flament MF, Rapoport JL, Murphy DL. Seasonal effects on platelet 5-HT content in patients with OCD and controls. Archives of General Psychiatry. 50: 409. PMID 8489330 DOI: 10.1001/Archpsyc.1993.01820170095015  0.346
1993 Grady TA, Pigott TA, L'Heureux F, Hill JL, Bernstein SE, Murphy DL. Double-blind study of adjuvant buspirone for fluoxetine-treated patients with obsessive-compulsive disorder. The American Journal of Psychiatry. 150: 819-21. PMID 8480832 DOI: 10.1176/Ajp.150.5.819  0.341
1993 Pigott TA, Hill JL, Grady TA, L'Heureux F, Bernstein S, Rubenstein CS, Murphy DL. A comparison of the behavioral effects of oral versus intravenous mCPP administration in OCD patients and the effect of metergoline prior to i.v. mCPP. Biological Psychiatry. 33: 3-14. PMID 8420593 DOI: 10.1016/0006-3223(93)90272-F  0.378
1993 Aulakh CS, Hill JL, Murphy DL. Differential effect of short- and long-term lithium treatment on m-CPP-induced neuroendocrine changes in rats. Neuroendocrinology. 57: 869-74. PMID 8413823 DOI: 10.1159/000126447  0.311
1993 Joseph-Vanderpool JR, Jacobsen FM, Murphy DL, Hill JL, Rosenthal NE. Seasonal variation in behavioral responses to m-CPP in patients with seasonal affective disorder and controls. Biological Psychiatry. 33: 496-504. PMID 8390305 DOI: 10.1016/0006-3223(93)90003-V  0.337
1993 Lesch KP, Aulakh CS, Wolozin BL, Tolliver TJ, Hill JL, Murphy DL. Regional brain expression of serotonin transporter mRNA and its regulation by reuptake inhibiting antidepressants. Brain Research. Molecular Brain Research. 17: 31-5. PMID 8381906 DOI: 10.1016/0169-328X(93)90069-2  0.356
1993 Lesch KP, Aulakh CS, Murphy DL. Brain serotonin subsystem complexity and receptor heterogeneity: therapeutic potential of selective serotonin agonists and antagonists. Psychopharmacology Series. 10: 52-69. PMID 8361982 DOI: 10.1007/978-3-642-78010-3_6  0.338
1993 Andrews AM, Murphy DL. 2'-NH2-MPTP in Swiss Webster mice: evidence for long-term (6-month) depletions in cortical and hippocampal serotonin and norepinephrine, differential protection by selective uptake inhibitors or clorgyline and functional changes in central serotonin neurotransmission. The Journal of Pharmacology and Experimental Therapeutics. 267: 1432-9. PMID 8263805  0.514
1993 Andrews AM, Murphy DL. Fluoxetine and desipramine selectively attenuate 2'-NH2-MPTP-induced depletions in serotonin and norepinephrine. European Journal of Pharmacology. 250: 215-21. PMID 8112382 DOI: 10.1016/0014-2999(93)90384-T  0.561
1993 Andrews AM, Murphy DL. Sustained depletion of cortical and hippocampal serotonin and norepinephrine but not striatal dopamine by 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine (2'-NH2-MPTP): a comparative study with 2'-CH3-MPTP and MPTP. Journal of Neurochemistry. 60: 1167-70. PMID 8094744 DOI: 10.1111/J.1471-4159.1993.Tb03271.X  0.549
1993 Altemus M, Pigott T, L'Heureux F, Davis CL, Rubinow DR, Murphy DL, Gold PW. CSF somatostatin in obsessive-compulsive disorder American Journal of Psychiatry. 150: 460-464. PMID 8094599 DOI: 10.1176/Ajp.150.3.460  0.357
1993 Lesch KP, Wolozin BL, Murphy DL, Riederer P. Primary structure of the human platelet serotonin uptake site: Identity with the brain serotonin transporter Journal of Neurochemistry. 60: 2319-2322. PMID 7684072 DOI: 10.1111/J.1471-4159.1993.Tb03522.X  0.341
1993 Murphy DL, Pigott TA, Grady TA, Lawlor B, Broocks A, Jacobsen F, Rosenthal N, Aulakh C, Lesch KP, Sunderland T. Affective, behavioral, and other non-endocrine physiologic responses to 5-HT 1 2 agonists and antagonists in humans European Neuropsychopharmacology. 3: 308-309. DOI: 10.1016/0924-977X(93)90089-5  0.377
1992 Klein E, Zohar J, Geraci MF, Murphy DL, Uhde TW. Anxiogenic effects of m-CPP in patients with panic disorder: comparison to caffeine's anxiogenic effects. Biological Psychiatry. 30: 973-84. PMID 1756202 DOI: 10.1016/0006-3223(91)90119-7  0.34
1992 Bihari K, Pigott TA, Hill JL, Murphy DL. Blepharospasm and obsessive-compulsive disorder. The Journal of Nervous and Mental Disease. 180: 130-2. PMID 1737975 DOI: 10.1097/00005053-199202000-00011  0.345
1992 Pigott TA, L’Heureux F, Hill JL, Bihari K, Bernstein SE, Murphy DL. A double-blind study of adjuvant buspirone hydrochloride in clomipramine-treated patients with obsessive-compulsive disorder Journal of Clinical Psychopharmacology. 12: 11-18. PMID 1552034 DOI: 10.1097/00001573-199202000-00003  0.319
1992 Bagdy G, Sved AF, Murphy DL, Szemeredi K. Pharmacological characterization of serotonin receptor subtypes involved in vasopressin and plasma renin activity responses to serotonin agonists. European Journal of Pharmacology. 210: 285-9. PMID 1535317 DOI: 10.1016/0014-2999(92)90417-3  0.344
1992 Bihari K, Hill JL, Murphy DL. Obsessive-compulsive characteristics in patients with idiopathic spasmodic torticollis. Psychiatry Research. 42: 267-72. PMID 1496058 DOI: 10.1016/0165-1781(92)90118-M  0.326
1992 Lesch KP, Aulakh CS, Wolozin BL, Murphy DL. Serotonin (5-HT) receptor, 5-HT transporter and G protein-effector expression: implications for depression Pharmacology & Toxicology. 71: 49-60. PMID 1480560 DOI: 10.1111/J.1600-0773.1992.Tb01629.X  0.341
1992 Brewerton TD, Mueller EA, Lesem MD, Brandt HA, Quearry B, George DT, Murphy DL, Jimerson DC. Neuroendocrine responses to m-chlorophenylpiperazine and L-tryptophan in bulimia. Archives of General Psychiatry. 49: 852-61. PMID 1444722 DOI: 10.1001/Archpsyc.1992.01820110016002  0.373
1992 Altemus M, Pigott T, Kalogeras KT, Demitrack M, Dubbert B, Murphy DL, Gold PW. Abnormalities in the Regulation of Vasopressin and Corticotropin Releasing Factor Secretion in Obsessive-Compulsive Disorder Archives of General Psychiatry. 49: 9-20. PMID 1370198 DOI: 10.1001/Archpsyc.1992.01820010009002  0.334
1992 Aulakh CS, Hill JL, Yoney HT, Murphy DL. Evidence for involvement of 5-HT1C and 5-HT2 receptors in the food intake suppressant effects of 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) Psychopharmacology. 109: 444-448. PMID 1365860 DOI: 10.1007/Bf02247721  0.306
1992 Collins FA, Murphy DL, Reiss AL, Sims KB, Lewis JG, Freund L, Karoum F, Zhu D, Maumenee IH, Antonarakis SE. Clinical, biochemical, and neuropsychiatric evaluation of a patient with a contiguous gene syndrome due to a microdeletion Xp11.3 including the Norrie disease locus and monoamine oxidase (MAOA and MAOB) genes. American Journal of Medical Genetics. 42: 127-34. PMID 1308352 DOI: 10.1002/Ajmg.1320420126  0.302
1992 PIGOTT TA, L??HEUREUX F, RUBENSTEIN CS, BERNSTEIN SE, HILL JL, MURPHY DL. A Double-Blind, Placebo Controlled Study of Trazodone Journal of Clinical Psychopharmacology. 12: 156???162. DOI: 10.1097/00004714-199206000-00002  0.382
1992 Murphy DL, Broocks A, Aulakh CS, Pigott TA. Anxiolytic effects of drugs acting on 5-HT receptor subtypes European Neuropsychopharmacology. 2: 287-288. DOI: 10.1016/0924-977X(92)90120-W  0.39
1991 Bihari K, Pato MT, Hill JL, Murphy DL. Neurologic soft signs in obsessive-compulsive disorder. Archives of General Psychiatry. 48: 278-9. PMID 2036127 DOI: 10.1001/Archpsyc.1991.01810270090013  0.309
1991 Pigott TA, Zohar J, Hill JL, Bernstein SE, Grover GN, Zohar-Kadouch RC, Murphy DL. Metergoline blocks the behavioral and neuroendocrine effects of orally administered m-chlorophenylpiperazine in patients with obsessive-compulsive disorder Biological Psychiatry. 29: 418-426. PMID 2018816 DOI: 10.1016/0006-3223(91)90264-M  0.312
1991 Murphy DL, Sims KB, Karoum F, Garrick NA, de la Chapelle A, Sankila EM, Norio R, Breakefield XO. Plasma amine oxidase activities in Norrie disease patients with an X-chromosomal deletion affecting monoamine oxidase. Journal of Neural Transmission. General Section. 83: 1-12. PMID 2018626 DOI: 10.1007/Bf01244447  0.333
1991 Pato MT, Pigott TA, Hill JL, Grover GN, Bernstein S, Murphy DL. Controlled comparison of buspirone and clomipramine in obsessive-compulsive disorder American Journal of Psychiatry. 148: 127-129. PMID 1984696 DOI: 10.1176/Ajp.148.1.127  0.367
1991 Pigott TA, Altemus M, Rubenstein CS, Hill JL, Bihari K, L'Heureux F, Bernstein S, Murphy DL. Symptoms of eating disorders in patients with obsessive-compulsive disorder American Journal of Psychiatry. 148: 1552-1557. PMID 1928472 DOI: 10.1176/Ajp.148.11.1552  0.324
1991 Aulakh CS, Zohar J, Wozniak KM, Hill JL, Haass M, Murphy DL. Differential effects of antidepressant treatments on fenfluramine-induced increases in plasma prolactin and corticosterone in rats. Pharmacology, Biochemistry, and Behavior. 39: 91-5. PMID 1924518 DOI: 10.1016/0091-3057(91)90402-N  0.31
1991 Lawlor BA, Sunderland T, Mellow AM, Molchan SE, Martinez R, Murphy DL. A pilot placebo-controlled study of chronic m-CPP administration in Alzheimer's disease. Biological Psychiatry. 30: 140-4. PMID 1912105 DOI: 10.1016/0006-3223(91)90167-K  0.331
1990 Murphy DL, Sims KB, Karoum F, Chapelle Adl, Norio R, Sankila E-, Breakefield XO. Marked Amine and Amine Metabolite Changes in Norrie Disease Patients with an X‐Chromosomal Deletion Affecting Monoamine Oxidase Journal of Neurochemistry. 54: 242-247. PMID 2293615 DOI: 10.1111/J.1471-4159.1990.Tb13307.X  0.315
1990 Insel TR, Zohar J, Benkelfat C, Murphy DL. Serotonin in obsessions, compulsions, and the control of aggressive impulses. Annals of the New York Academy of Sciences. 600: 574-85; discussion 5. PMID 2252336 DOI: 10.1111/J.1749-6632.1990.Tb16911.X  0.311
1990 Mellow AM, Lawlor BA, Sunderland T, Mueller EA, Molchan SE, Murphy DL. Effects of daily oral m-chlorophenylpiperazine in elderly depressed patients. Initial experience with a serotonin agonist. Biological Psychiatry. 28: 588-94. PMID 2223928 DOI: 10.1016/0006-3223(90)90396-J  0.349
1990 Pigott TA, Pato MT, Bernstein SE, Grover GN, Hill JL, Tolliver TJ, Murphy DL. Controlled Comparisons of Clomipramine and Fluoxetine in the Treatment of Obsessive-Compulsive Disorder: Behavioral and Biological Results Archives of General Psychiatry. 47: 926-932. PMID 2222131 DOI: 10.1001/Archpsyc.1990.01810220042005  0.379
1990 Bagdy G, Calogero AE, Szemeredi K, Gomez MT, Murphy DL, Chrousos GP, Gold PW. β-Endorphin responses to different serotonin agonists: involvement of corticotropin-releasing hormone, vasopressin and direct pituitary action Brain Research. 537: 227-232. PMID 2150776 DOI: 10.1016/0006-8993(90)90362-F  0.307
1990 MURPHY DL, PATO MT, PIGOTT TA. Obsessive-Compulsive Disorder Journal of Clinical Psychopharmacology. 10: 91S-100S. DOI: 10.1097/00004714-199006001-00016  0.377
1989 Bagdy G, Szemeredi K, Hill JL, Murphy DL. The serotonin agonist, M-chlorophenylpiperazine, markedly increases levels of plasma catecholamines in the conscious rat. Neuropharmacology. 27: 975-80. PMID 3237317 DOI: 10.1016/0028-3908(88)90055-X  0.316
1989 Pato MT, Zohar-Kadouch R, Zohar J, Murphy DL. Return of symptoms after discontinuation of clomipramine in patients with obsessive-compulsive disorder. The American Journal of Psychiatry. 145: 1521-5. PMID 3057923 DOI: 10.1176/Ajp.145.12.1521  0.327
1989 Lawlor BA, Sunderland T, Mellow AM, Hill JL, Newhouse PA, Murphy DL. A preliminary study of the effects of intravenous m-chlorophenylpiperazine, a serotonin agonist, in elderly subjects. Biological Psychiatry. 25: 679-86. PMID 2923931 DOI: 10.1016/0006-3223(89)90237-0  0.33
1989 Benkelfat C, Murphy DL, Zohar J, Hill JL, Grover G, Insel TR. Clomipramine in obsessive-compulsive disorder. Further evidence for a serotonergic mechanism of action. Archives of General Psychiatry. 46: 23-8. PMID 2910220 DOI: 10.1001/Archpsyc.1989.01810010025004  0.391
1989 Lawlor BA, Sunderland T, Hill JL, Mellow AM, Molchan SE, Mueller EA, Jacobsen FM, Murphy DL. Evidence for a decline with age in behavioral responsivity to the serotonin agonist, m-chlorophenylpiperazine, in healthy human subjects. Psychiatry Research. 29: 1-10. PMID 2772095 DOI: 10.1016/0165-1781(89)90181-9  0.335
1989 Aulakh CS, Haass M, Zohar J, Wozniak KM, Hill JL, Murphy DL. Long-term imipramine treatment potentiates m-chlorophenylpiperazine-induced changes in prolactin but not corticosterone or growth hormone levels in rats. Pharmacology, Biochemistry, and Behavior. 32: 37-42. PMID 2734349 DOI: 10.1016/0091-3057(89)90207-4  0.306
1989 Lawlor BA, Sunderland T, Mellow AM, Hill JL, Molchan SE, Murphy DL. Hyperresponsivity to the serotonin agonist m-chlorophenylpiperazine in Alzheimer's disease. A controlled study. Archives of General Psychiatry. 46: 542-9. PMID 2730278 DOI: 10.1001/Archpsyc.1989.01810060064010  0.301
1989 Murphy DL, Zohar J, Benkelfat C, Pato MT, Pigott TA, Insel TR. Obsessive-compulsive disorder as a 5-HT subsystem-related behavioural disorder. The British Journal of Psychiatry. Supplement. 15-24. PMID 2692636 DOI: 10.1192/S0007125000291721  0.396
1989 Kishore-Kumar R, Schafer SC, Lawlor BA, Murphy DL, Max MB. Single doses of the serotonin agonists buspirone and m-chlorophenylpiperazine do not relieve neuropathic pain. Pain. 37: 223-7. PMID 2664664 DOI: 10.1016/0304-3959(89)90134-6  0.316
1989 Donnelly M, Rapoport JL, Potter WZ, Oliver J, Keysor CS, Murphy DL. Fenfluramine and dextroamphetamine treatment of childhood hyperactivity. Clinical and biochemical findings. Archives of General Psychiatry. 46: 205-12. PMID 2645848 DOI: 10.1001/Archpsyc.1989.01810030011002  0.333
1989 Bagdy G, Calogero AE, Aulakh CS, Szemeredi K, Murphy DL. Long-term cortisol treatment impairs behavioral and neuroendocrine responses to 5-HT1 agonists in the rat. Neuroendocrinology. 50: 241-7. PMID 2552339 DOI: 10.1159/000125248  0.371
1989 Bagdy G, Calogero AE, Murphy DL, Szemeredi K. Serotonin agonists cause parallel activation of the sympathoadrenomedullary system and the hypothalamo-pituitary-adrenocortical axis in conscious rats. Endocrinology. 125: 2664-9. PMID 2551661 DOI: 10.1210/Endo-125-5-2664  0.365
1989 Wozniak KM, Aulakh CS, Hill JL, Murphy DL. Hyperthermia induced by m-CPP in the rat and its modification by antidepressant treatments. Psychopharmacology. 97: 269-74. PMID 2498937 DOI: 10.1007/Bf00442262  0.321
1989 Aulakh CS, Wozniak KM, Hill JL, Devane CL, Tolliver TJ, Murphy DL. Differential neuroendocrine responses to the 5-HT agonist m-chlorophenylpiperazine in Fawn-Hooded rats relative to Wistar and Sprague-Dawley rats. Neuroendocrinology. 48: 401-6. PMID 2463494 DOI: 10.1159/000125041  0.311
1989 Aulakh CS, Cohen RM, Dauphin MM, McLellan CA, Murphy DL. Role of serotonergic input in the down-regulation of beta-adrenoceptors following long-term clorgyline treatment. European Journal of Pharmacology. 156: 63-70. PMID 2463178 DOI: 10.1016/0014-2999(88)90147-1  0.352
1989 Brewerton T, Murphy D, Jimerson DC. A comparison of neuroendocrine responses to L-TRP and m-CPP in bulimics and controls Biological Psychiatry. 25: A19. DOI: 10.1016/0006-3223(89)91524-2  0.306
1988 Brewerton TD, Murphy DL, Mueller EA, Jimerson DC. Induction of migrainelike headaches by the serotonin agonist m-chlorophenylpiperazine. Clinical Pharmacology and Therapeutics. 43: 605-9. PMID 3378382 DOI: 10.1038/Clpt.1988.83  0.361
1988 Zohar J, Insel TR, Zohar-Kadouch RC, Hill JL, Murphy DL. Serotonergic responsivity in obsessive-compulsive disorder. Effects of chronic clomipramine treatment. Archives of General Psychiatry. 45: 167-72. PMID 3276283 DOI: 10.1001/Archpsyc.1988.01800260081011  0.367
1988 Szele FG, Murphy DL, Garrick NA. Effects of fenfluramine, m-chlorophenylpiperazine, and other serotonin-related agonists and antagonists on penile erections in nonhuman primates. Life Sciences. 43: 1297-303. PMID 3172981 DOI: 10.1016/0024-3205(88)90584-X  0.335
1988 Wozniak KM, Aulakh CS, Hill JL, Murphy DL. The effect of 8-OH-DPAT on temperature in the rat and its modification by chronic antidepressant treatments. Pharmacology, Biochemistry, and Behavior. 30: 451-6. PMID 2971978 DOI: 10.1016/0091-3057(88)90479-0  0.31
1988 Wang P, Aulakh CS, Hill JL, Murphy DL. Fawn hooded rats are subsensitive to the food intake suppressant effects of 5-HT agonists. Psychopharmacology. 94: 558-62. PMID 2967518 DOI: 10.1007/Bf00212855  0.318
1987 Zohar J, Mueller EA, Insel TR, Zohar-Kadouch RC, Murphy DL. Serotonergic responsivity in obsessive-compulsive disorder. Comparison of patients and healthy controls. Archives of General Psychiatry. 44: 946-51. PMID 3675134 DOI: 10.1001/Archpsyc.1987.01800230026006  0.357
1987 Flament MF, Rapoport JL, Murphy DL, Berg CJ, Lake CR. Biochemical changes during clomipramine treatment of childhood obsessive-compulsive disorder. Archives of General Psychiatry. 44: 219-25. PMID 3548637 DOI: 10.1001/Archpsyc.1987.01800150025004  0.359
1987 Tariot PN, Cohen RM, Sunderland T, Newhouse PA, Yount D, Mellow AM, Weingartner H, Mueller EA, Murphy DL. L-deprenyl in Alzheimer's disease. Preliminary evidence for behavioral change with monoamine oxidase B inhibition. Archives of General Psychiatry. 44: 427-33. PMID 3107514 DOI: 10.1001/Archpsyc.1987.01800170041007  0.319
1987 Sunderland T, Tariot PN, Cohen RM, Newhouse PA, Mellow AM, Mueller EA, Murphy DL. Dose-dependent effects of deprenyl on CSF monoamine metabolites in patients with Alzheimer's disease. Psychopharmacology. 91: 293-6. PMID 2436247 DOI: 10.1007/Bf00518180  0.317
1986 Mueller EA, Murphy DL, Sunderland T. Further studies of the putative serotonin agonist, m-chlorophenylpiperazine: evidence for a serotonin receptor mediated mechanism of action in humans. Psychopharmacology. 89: 388-91. PMID 3014595 DOI: 10.1007/Bf00174380  0.334
1986 Murphy DL, Tamarkin L, Sunderland T, Garrick NA, Cohen RM. Human plasma melatonin is elevated during treatment with the monoamine oxidase inhibitors clorgyline and tranylcypromine but not deprenyl. Psychiatry Research. 17: 119-27. PMID 3008207 DOI: 10.1016/0165-1781(86)90067-3  0.307
1985 Campbell IC, Durcan MJ, Cohen RM, Pickar D, Chugani D, Murphy DL. Chronic clorgyline and pargyline increase apomorphine-induced stereotypy in the rat Pharmacology, Biochemistry and Behavior. 23: 921-925. PMID 4080777 DOI: 10.1016/0091-3057(85)90093-0  0.303
1985 Mueller EA, Murphy DL, Sunderland T. Neuroendocrine effects of M-chlorophenylpiperazine, a serotonin agonist, in humans. The Journal of Clinical Endocrinology and Metabolism. 61: 1179-84. PMID 4055985 DOI: 10.1210/Jcem-61-6-1179  0.332
1985 Insel TR, Mueller EA, Gillin JC, Siever LJ, Murphy DL. Tricyclic response in obsessive compulsive disorder. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 9: 25-31. PMID 3991911 DOI: 10.1016/0278-5846(85)90176-9  0.346
1985 Zametkin A, Rapoport JL, Murphy DL, Linnoila M, Ismond D. Treatment of hyperactive children with monoamine oxidase inhibitors. I. Clinical efficacy. Archives of General Psychiatry. 42: 962-6. PMID 3899047 DOI: 10.1001/Archpsyc.1985.01790330042005  0.304
1985 Cohen RM, Aulakh C, McLellan C, Murphy DL. 6-Hydroxydopamine pretreatment effects on alpha- and beta-adrenergic receptor adaptation to clorgyline. Naunyn-Schmiedeberg's Archives of Pharmacology. 329: 158-61. PMID 2989714 DOI: 10.1007/Bf00501206  0.326
1985 Murphy DL, Siever LJ, Insel TR. Therapeutic responses to tricyclic antidepressants and related drugs in non-affective disorder patient populations. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 9: 3-13. PMID 2986199 DOI: 10.1016/0278-5846(85)90174-5  0.359
1985 Insel TR, Mueller EA, Alterman I, Linnoila M, Murphy DL. Obsessive-compulsive disorder and serotonin: is there a connection? Biological Psychiatry. 20: 1174-88. PMID 2413912 DOI: 10.1016/0006-3223(85)90176-3  0.405
1985 Garrick NA, Seppala T, Linnoila M, Murphy DL. The effects of amiflamine on cerebrospinal fluid amine metabolites in the rhesus monkey. European Journal of Pharmacology. 110: 1-9. PMID 2408906 DOI: 10.1016/0014-2999(85)90022-6  0.319
1984 Aloi JA, Insel TR, Mueller EA, Murphy DL. Neuroendocrine and behavioral effects of m-chlorophenylpiperazine administration in rhesus monkeys. Life Sciences. 34: 1325-31. PMID 6708733 DOI: 10.1016/0024-3205(84)90003-1  0.327
1984 Siever LJ, Murphy DL, Slater S, de la Vega E, Lipper S. Plasma prolactin changes following fenfluramine in depressed patients compared to controls: An evaluation of central serotonergic responsibility in depression Life Sciences. 34: 1029-1039. PMID 6700367 DOI: 10.1016/0024-3205(84)90016-X  0.305
1984 Siever LJ, Uhde TW, Jimerson DC, Post RM, Lake CR, Murphy DL. Plasma cortisol responses to clonidine in depressed patients and controls. Evidence for a possible alteration in noradrenergic-neuroendocrine relationships. Archives of General Psychiatry. 41: 63-8. PMID 6691786 DOI: 10.1001/Archpsyc.1984.01790120067009  0.309
1984 Cohen RM, Aulakh CS, Murphy DL. Long-term clorgyline treatment antagonizes the eating and motor function responses to m-chlorophenylpiperazine. European Journal of Pharmacology. 94: 175-9. PMID 6653658 DOI: 10.1016/0014-2999(83)90459-4  0.311
1984 Insel TR, Mueller EA, Gillin JC, Siever LJ, Murphy DL. Biological markers in obsessive-compulsive and affective disorders. Journal of Psychiatric Research. 18: 407-23. PMID 6512711 DOI: 10.1016/0022-3956(84)90030-X  0.356
1984 Zahn TP, Insel TR, Murphy DL. Psychophysiological changes during pharmacological treatment of patients with obsessive compulsive disorder. The British Journal of Psychiatry : the Journal of Mental Science. 145: 39-44. PMID 6378303 DOI: 10.1192/Bjp.145.1.39  0.312
1984 Garrick NA, Scheinin M, Chang WH, Linnoila M, Murphy DL. Differential effects of clorgyline on catecholamine and indoleamine metabolites in the cerebrospinal fluid of rhesus monkeys. Biochemical Pharmacology. 33: 1423-7. PMID 6203542 DOI: 10.1016/0006-2952(84)90408-8  0.321
1984 Murphy DL, Mueller EA, Insel T, Siever LJ, Aulakh C, Cohen RM. BIOLOGIC MARKERS FOR SEROTONERGIC DYSFUNCTION IN PSYCHIATRIC DISORDERS Clinical Neuropharmacology. 7: S154. DOI: 10.1097/00002826-198406001-00142  0.323
1983 Garrick NA, Murphy DL. Monoamine oxidase type A: differences in selectivity towards l-norepinephrine compared to serotonin. Biochemical Pharmacology. 31: 4061-6. PMID 7159481 DOI: 10.1016/0006-2952(82)90656-6  0.31
1983 Insel TR, Hamilton JA, Guttmacher LB, Murphy DL. D-amphetamine in obsessive-compulsive disorder. Psychopharmacology. 80: 231-5. PMID 6412267 DOI: 10.1007/Bf00436159  0.317
1983 Insel TR, Murphy DL, Cohen RM, Alterman I, Kilts C, Linnoila M. Obsessive-compulsive disorder. A double-blind trial of clomipramine and clorgyline. Archives of General Psychiatry. 40: 605-12. PMID 6342562 DOI: 10.1001/Archpsyc.1983.04390010015002  0.349
1983 Siever LJ, Uhde TW, Jimerson DC, Kafka MS, Lake CR, Targum S, Murphy DL. Clinical studies of monoamine receptors in the affective disorders and receptor changes with antidepressant treatment. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 7: 249-61. PMID 6310694 DOI: 10.1016/0278-5846(83)90115-X  0.323
1983 Lake R, Pickar D, Zeigler M, Lipper S, Slater S, Murphy D. High plasma norepinephrine levels in patients with major affective disorder Journal of Clinical Psychopharmacology. 3: 118. DOI: 10.1097/00004714-198304000-00028  0.311
1983 SIEVER LJ, PICKAR D, LAKE R, COHEN RM, UHDE TW, MURPHY DL. Extreme Elevations in Plasma Norepinephrine Associated with Decreased ??-Adrenergic Responsivity in Major Depressive Disorder Journal of Clinical Psychopharmacology. 3: 39???41. DOI: 10.1097/00004714-198302000-00010  0.326
1982 Costa JL, Murphy DL, Stark H. Applicability of models for carrier-mediated serotonin transport to pools of serotonin in intact human platelets. The Journal of Physiology. 316: 153-61. PMID 7320861 DOI: 10.1113/Jphysiol.1981.Sp013779  0.335
1982 Donnelly EF, Murphy DL, Goodwin FK, Waldman IN. Intellectual function in primary affective disorder. The British Journal of Psychiatry : the Journal of Mental Science. 140: 633-6. PMID 7104555 DOI: 10.1192/Bjp.140.6.633  0.308
1982 Pickar D, Murphy DL, Cohen RM, Campbell IC, Lipper S. Selective and Nonselective Monoamine Oxidase Inhibitors: Behavioral Disturbances During Their Administration to Depressed Patients Archives of General Psychiatry. 39: 535-540. PMID 7092487 DOI: 10.1001/Archpsyc.1982.04290050023006  0.317
1982 Potter WZ, Murphy DL, Wehr TA, Linnoila M, Goodwin FK. Clorgyline. A new treatment for patients with refractory rapid-cycling disorder. Archives of General Psychiatry. 39: 505-10. PMID 6807254 DOI: 10.1001/Archpsyc.1982.04290050001001  0.312
1981 Costa JL, Kirk KL, Murphy DL, Stark H. Anomalous compartmentation of 5-hydroxytryptamine in intact human platelets. British Journal of Pharmacology. 72: 449-59. PMID 7260486 DOI: 10.1111/J.1476-5381.1981.Tb10996.X  0.31
1981 Kalin NH, Risch SC, Murphy DL. Involvement of the central serotonergic system in affective illness. Journal of Clinical Psychopharmacology. 1: 232-7. PMID 7028804 DOI: 10.1097/00004714-198107000-00008  0.355
1981 Garrick NA, Murphy DL. Species differences in the deamination of dopamine and other substrates for monoamine oxidase in brain. Psychopharmacology. 72: 27-33. PMID 6781004 DOI: 10.1007/Bf00433804  0.314
1981 Eisler T, Teräväinen H, Nelson R, Krebs H, Weise V, Lake CR, Ebert MH, Whetzel N, Murphy DL, Kopin IJ, Calne DB. Deprenyl in Parkinson disease. Neurology. 31: 19-23. PMID 6161320 DOI: 10.1212/Wnl.31.1.19  0.305
1981 Risch SC, Kalin NH, Murphy DL. Neurochemical mechanisms in the affective disorders and neuroendocrine correlates. Journal of Clinical Psychopharmacology. 1: 180-5. PMID 6117585 DOI: 10.1097/00004714-198107000-00002  0.31
1980 Lerner P, Major LF, Dendel PS, Campbell IC, Murphy DL. Central and peripheral dopamine beta hydroxylase: responses to long term treatment with monoamine oxidase inhibitors. Neuropharmacology. 19: 877-81. PMID 7422098 DOI: 10.1016/0028-3908(80)90087-8  0.303
1980 Haier RJ, Buchsbaum MS, Murphy DL. An 18-month followup of students biologically at risk for psychiatric problems. Schizophrenia Bulletin. 6: 334-7. PMID 7375866 DOI: 10.1093/Schbul/6.2.334  0.31
1980 Murphy DL, Kalin NH. Biological and behavioral consequences of alterations in monoamine oxidase activity. Schizophrenia Bulletin. 6: 355-67. PMID 6103577 DOI: 10.1093/Schbul/6.2.355  0.309
1979 Costa JL, Pettigrew KD, Murphy DL. Electron probe microanalysis of changes in dense-body phosphorus and calcium content following alterations in platelet serotonin levels. Biochemical Pharmacology. 28: 23-6. PMID 758907 DOI: 10.1016/0006-2952(79)90264-8  0.313
1979 Campbell IC, Shiling DJ, Lipper S, Slater S, Murphy DL. A biochemical measure of monoamine oxidase type A and B inhibitor effects in man. Journal of Psychiatric Research. 15: 77-84. PMID 490428 DOI: 10.1016/0022-3956(79)90020-7  0.308
1979 Coursey RD, Buchsbaum MS, Murphy DL. Platelet MAO activity and evoked potentials in the identification of subjects biologically at risk for psychiatric disorders. The British Journal of Psychiatry : the Journal of Mental Science. 134: 372-81. PMID 444787 DOI: 10.1192/Bjp.134.4.372  0.301
1979 Murphy DL, Campbell IC, Costa JL. The brain serotonergic system in the affective disorders. Progress in Neuro-Psychopharmacology. 2: 5-31. PMID 214806 DOI: 10.1016/0364-7722(78)90019-X  0.397
1979 Lipper S, Murphy DL, Slater S, Buchsbaum MS. Comparative behavioral effects of clorgyline and pargyline in man: a preliminary evaluation. Psychopharmacology. 62: 123-8. PMID 111274 DOI: 10.1007/Bf00427124  0.314
1979 Campbell IC, Robinson DS, Lovenberg W, Murphy DL. The effects of chronic regimens of clorgyline and pargyline on monoamine metabolism in the rat brain. Journal of Neurochemistry. 32: 49-55. PMID 32233 DOI: 10.1111/J.1471-4159.1979.Tb04508.X  0.321
1979 Raymond Lake C, Coleman MD, Ziegler MG, Murphy DL. Fenfluramine and its effects on the sympathetic nervous system in man Current Medical Research and Opinion. 6: 63-72. DOI: 10.1185/03007997909117492  0.306
1978 Costa JL, Murphy DL, Reveille J. Evaluation of the uptake of various amines into storage vesicles of intact human platelets. British Journal of Pharmacology. 61: 223-8. PMID 922252 DOI: 10.1111/J.1476-5381.1977.Tb08408.X  0.335
1978 Costa JL, Stark H, Shafer B, Corash L, Smith MA, Murphy DL. Maximal packet size for serotonin in storage vesicles of intact human platelets. Life Sciences. 23: 2193-7. PMID 723471 DOI: 10.1016/0024-3205(78)90203-5  0.319
1978 Buchsbaum MS, Murphy DL, Coursey RD, Lake CR, Zeigler MG. Platelet monoamine oxidase, plasma dopamine-beta-hydroxylase and attention in a "biochemical high risk" sample. Journal of Psychiatric Research. 14: 215-24. PMID 722628 DOI: 10.1016/0022-3956(78)90024-9  0.315
1978 Costa JL, Murphy DL, Smith MA, Pettigrew KD. Effects of antimycin A plus 2-deoxyglucose on uptake and vesicular storage of serotonin in human platelets. Life Sciences. 22: 1811-6. PMID 672429 DOI: 10.1016/0024-3205(78)90597-0  0.334
1977 Costa JL, Silber SA, Murphy DL. Effects of reserpine and imipramine on vesicular serotonin uptake and storage in intact human platelets. Life Sciences. 21: 181-8. PMID 886915 DOI: 10.1016/0024-3205(77)90300-9  0.338
1977 Leckman JF, Gershon ES, Nichols AS, Murphy DL. Reduced MAO activity in first-degree relatives of individuals with bipolar affective disorders. A preliminary report. Archives of General Psychiatry. 34: 601-6. PMID 871234 DOI: 10.1001/Archpsyc.1977.01770170111011  0.321
1977 Costa JL, Murphy DL, Kafka MS. Demonstration and evaluation of apparent cytoplasmic and vesicular serotonin compartments in human platelets. Biochemical Pharmacology. 26: 517-21. PMID 849349 DOI: 10.1016/0006-2952(77)90327-6  0.321
1977 de la Vega CE, Slater S, Ziegler MG, Lake CR, Murphy DL. Reduction in plasma norepinephrine during fenfluramine treatment. Clinical Pharmacology and Therapeutics. 21: 216-21. PMID 319936 DOI: 10.1002/Cpt1977212216  0.303
1977 Murphy DL. The behavioral toxicity of monoamine oxidase-inhibiting antidepressants. Advances in Pharmacology and Chemotherapy. 14: 71-105. PMID 18913 DOI: 10.1016/S1054-3589(08)60185-4  0.315
1977 Costa JL, Murphy DL. Alterations in Human-Platelet Serotonin Uptake Following the Addition of Thrombin or A 23187 Thrombosis and Haemostasis. 37: 177-179. DOI: 10.1055/S-0038-1649216  0.31
1976 Buchsbaum MS, Coursey RD, Murphy DL. The biochemical high risk paradigm: behavioral and familial correlates of low platelet monoamine oxidase activity Science. 194: 339-341. PMID 968488 DOI: 10.1126/Science.968488  0.312
1976 Donnelly CH, Richelson E, Murphy DL. Properties of monoamine oxidase in mouse neuroblastoma N1E-115 cells. Biochemical Pharmacology. 25: 1639-43. PMID 942463 DOI: 10.1016/0006-2952(76)90476-7  0.344
1976 Murphy DL. Chapter 5: Biological Factors in Psychiatric Disorders Annual Reports in Medicinal Chemistry. 11: 42-50. DOI: 10.1016/S0065-7743(08)61388-3  0.314
1975 Donnelly EF, Murphy DL, Scott WH. Perception and cognition in patients with bipolar and unipolar depressive disorders. A study in orschach responding. Archives of General Psychiatry. 32: 1128-31. PMID 1180662 DOI: 10.1001/Archpsyc.1975.01760270060006  0.309
1975 Costa JL, Murphy DL. Platelet 5-HT uptake and release stopped rapidly by formaldehyde. Nature. 255: 407-8. PMID 1128701 DOI: 10.1038/255407A0  0.308
1975 Goodwin FK, Murphy DL. Chapter 5. Biological Factors in the Major Psychoses Annual Reports in Medicinal Chemistry. 10: 39-50. DOI: 10.1016/S0065-7743(08)60993-8  0.361
1974 Carlson HE, Robbins J, Murphy DL. The effects of lithium on thyroid iodine release in patients with primary affective disorder. Psychopharmacologia. 35: 249-56. PMID 4829324 DOI: 10.1007/Bf00437754  0.3
1974 Rapoport J, Quinn P, Scribanu N, Murphy DL. Platelet serotonin of hyperactive school age boys. The British Journal of Psychiatry : the Journal of Mental Science. 125: 138-40. PMID 4606916 DOI: 10.1192/Bjp.125.2.138  0.324
1974 Murphy DL, Baker M, Goodwin FK, Miller H, Kotin J, Bunney WE. l-Tryptophan in affective disorders: Indoleamine changes and differential clinical effects Psychopharmacology. 34: 11-20. PMID 4593517 DOI: 10.1007/Bf00421216  0.332
1974 Murphy DL, Belmaker R, Wyatt RJ. Monamine oxidase in schizophrenia and other behavioral disorders. Journal of Psychiatric Research. 11: 221-47. PMID 4461792 DOI: 10.1016/0022-3956(74)90097-1  0.313
1973 Murphy DL, Mendell JR, Engel WK. Serotonin and platelet function in Duchenne muscular dystrophy. Archives of Neurology. 28: 239-42. PMID 4688430 DOI: 10.1001/Archneur.1973.00490220047006  0.353
1973 Murphy DL, Goodwin FK, Brodie HK, Bunney WE. L-dopa, dopamine, and hypomania. The American Journal of Psychiatry. 130: 79-82. PMID 4682751 DOI: 10.1176/Ajp.130.1.79  0.301
1973 Lott IT, Chase TN, Murphy DL. Down's syndrome: transport, storage, and metabolism of serotonin in blood platelets. Pediatric Research. 6: 730-5. PMID 4264688 DOI: 10.1203/00006450-197209000-00006  0.336
1973 Donnelly EF, Murphy DL. Primary affective disorder: delineation of a unipolar depressive subtype Psychological Reports. 32. PMID 4145089 DOI: 10.2466/Pr0.1973.32.3.744  0.32
1972 Murphy DL, Weiss R. Reduced monoamine oxidase activity in blood platelets from bipolar depressed patients. The American Journal of Psychiatry. 128: 1351-7. PMID 5020182 DOI: 10.1176/Ajp.128.11.1351  0.314
1972 Murphy DL, Wyatt RJ. Reduced monoamine oxidase activity in blood platelets from schizophrenic patients. Nature. 238: 225-6. PMID 4558353 DOI: 10.1038/238225A0  0.305
1972 Bunney WE, Goodwin FK, Murphy DL, House KM, Gordon EK. The "switch process" in manic-depressive illness. II. Relationship to catecholamines, REM sleep, and drugs. Archives of General Psychiatry. 27: 304-9. PMID 4340658 DOI: 10.1001/Archpsyc.1972.01750270014002  0.3
1972 Murphy DL. Amine precursors, amines, and false neurotransmitters in depressed patients. The American Journal of Psychiatry. 129: 141-8. PMID 4339314 DOI: 10.1176/Ajp.129.2.141  0.303
1972 Murphy DL, Goodwin FK, Bunney WE. A Reevaluation of Biogenic Amines in Manic and Depressive States Hospital Practice. 7: 85-92. DOI: 10.1080/21548331.1972.11706305  0.31
1971 Beigel A, Murphy DL. Unipolar and bipolar affective illness. Differences in clinical characteristics accompanying depression. Archives of General Psychiatry. 24: 215-20. PMID 5100617 DOI: 10.1001/Archpsyc.1971.01750090021003  0.305
1970 Murphy DL, Colburn RW, Davis JM, Bunney WE. Imipramine and lithium effects of biogenic amine transport in depressed and manic-depressed patients. The American Journal of Psychiatry. 127: 339-45. PMID 5458598 DOI: 10.1176/Ajp.127.3.339  0.319
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