Dennis L. Murphy - Publications

Affiliations: 
NIMH/NIH National Institute of Health, Bethesda, MD, United States 
Area:
OCD, serotonin transporter
Website:
http://neuroscience.nih.gov/Lab.asp?Org_ID=172

235 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Delgado-Acevedo C, Estay SF, Radke AK, Sengupta A, Escobar AP, Henríquez-Belmar F, Reyes CA, Haro-Acuña V, Utreras E, Sotomayor-Zárate R, Cho A, Wendland JR, Kulkarni AB, Holmes A, Murphy DL, et al. Correction: Behavioral and synaptic alterations relevant to obsessivecompulsive disorder in mice with increased EAAT3 expression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30787427 DOI: 10.1038/s41386-019-0331-x  1
2018 Delgado-Acevedo C, Estay SF, Radke A, Sengupta A, Escobar AP, Henríquez-Belmar F, Reyes C, Haro V, Utreras E, Sotomayor-Zárate R, Cho A, Wendland JR, Kulkarni AB, Holmes A, Murphy DL, et al. Behavioral and synaptic alterations relevant to obsessive-compulsive disorder in mice with increased EAAT3 expression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30622300 DOI: 10.1038/s41386-018-0302-7  1
2017 González LF, Henríquez-Belmar F, Delgado-Acevedo C, Cisternas-Olmedo M, Arriagada G, Sotomayor-Zárate R, Murphy DL, Moya PR. Neurochemical and behavioral characterization of neuronal glutamate transporter EAAT3 heterozygous mice. Biological Research. 50: 29. PMID 28927446 DOI: 10.1186/s40659-017-0138-3  1
2016 Park JM, Samuels JF, Grados MA, Riddle MA, Bienvenu OJ, Goes FS, Cullen B, Wang Y, Krasnow J, Murphy DL, Rasmussen SA, McLaughlin NC, Piacentini J, Pauls DL, Stewart SE, et al. ADHD and executive functioning deficits in OCD youths who hoard. Journal of Psychiatric Research. 82: 141-148. PMID 27501140 DOI: 10.1016/j.jpsychires.2016.07.024  1
2015 Riddle MA, Maher BS, Wang Y, Grados M, Bienvenu OJ, Goes FS, Cullen B, Murphy DL, Rauch SL, Greenberg BD, Knowles JA, McCracken JT, Pinto A, Piacentini J, Pauls DL, et al. OBSESSIVE-COMPULSIVE PERSONALITY DISORDER: EVIDENCE FOR TWO DIMENSIONS. Depression and Anxiety. PMID 26594839 DOI: 10.1002/da.22452  1
2015 Mroczkowski MM, Goes FS, Riddle MA, Grados MA, Bienvenu OJ, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Knowles JA, Piacentini J, Cullen B, Rasmussen SA, Pauls DL, et al. Dependent personality, separation anxiety disorder and other anxiety disorders in OCD. Personality and Mental Health. PMID 26542617 DOI: 10.1002/pmh.1321  1
2015 Qin H, Samuels JF, Wang Y, Zhu Y, Grados MA, Riddle MA, Greenberg BD, Knowles JA, Fyer AJ, McCracken JT, Murphy DL, Rasmussen SA, Cullen BA, Piacentini J, Geller D, et al. Whole-genome association analysis of treatment response in obsessive-compulsive disorder. Molecular Psychiatry. PMID 25824302 DOI: 10.1038/mp.2015.32  1
2015 Piao YS, Hall FS, Moriya Y, Ito M, Ohara A, Kikura-Hanajiri R, Goda Y, Lesch KP, Murphy DL, Uhl GR, Sora I. Methylone-induced hyperthermia and lethal toxicity: role of the dopamine and serotonin transporters. Behavioural Pharmacology. 26: 345-52. PMID 25794333 DOI: 10.1097/FBP.0000000000000135  0.4
2015 Igari M, Shen HW, Hagino Y, Fukushima S, Kasahara Y, Lesch KP, Murphy DL, Hall FS, Uhl GR, Ikeda K, Yaegashi N, Sora I. Attenuated methamphetamine-induced locomotor sensitization in serotonin transporter knockout mice is restored by serotonin 1B receptor antagonist treatment. Behavioural Pharmacology. 26: 167-79. PMID 25485646 DOI: 10.1097/FBP.0000000000000120  0.4
2015 Yu D, Mathews CA, Scharf JM, Neale BM, Davis LK, Gamazon ER, Derks EM, Evans P, Edlund CK, Crane J, Fagerness JA, Osiecki L, Gallagher P, Gerber G, Haddad S, ... ... Murphy DL, et al. Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD. The American Journal of Psychiatry. 172: 82-93. PMID 25158072 DOI: 10.1176/appi.ajp.2014.13101306  0.32
2015 Mattheisen M, Samuels JF, Wang Y, Greenberg BD, Fyer AJ, McCracken JT, Geller DA, Murphy DL, Knowles JA, Grados MA, Riddle MA, Rasmussen SA, McLaughlin NC, Nurmi EL, Askland KD, et al. Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS. Molecular Psychiatry. 20: 337-44. PMID 24821223 DOI: 10.1038/mp.2014.43  1
2014 Samuels J, Grados MA, Riddle MA, Bienvenu OJ, Goes FS, Cullen B, Wang Y, Greenberg BD, Fyer AJ, McCracken JT, Geller D, Murphy DL, Knowles JA, Rasmussen SA, McLaughlin NC, et al. Hoarding in Children and Adolescents with Obsessive-Compulsive Disorder. Journal of Obsessive-Compulsive and Related Disorders. 3: 325-331. PMID 25309849 DOI: 10.1016/j.jocrd.2014.08.001  1
2014 McGrath LM, Yu D, Marshall C, Davis LK, Thiruvahindrapuram B, Li B, Cappi C, Gerber G, Wolf A, Schroeder FA, Osiecki L, O'Dushlaine C, Kirby A, Illmann C, Haddad S, ... ... Murphy DL, et al. Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study. Journal of the American Academy of Child and Adolescent Psychiatry. 53: 910-9. PMID 25062598 DOI: 10.1016/j.jaac.2014.04.022  1
2014 Samuels J, Shugart YY, Wang Y, Grados MA, Bienvenu OJ, Pinto A, Rauch SL, Greenberg BD, Knowles JA, Fyer AJ, Piacentini J, Pauls DL, Cullen B, Rasmussen SA, Stewart SE, ... ... Murphy DL, et al. Clinical correlates and genetic linkage of social and communication difficulties in families with obsessive-compulsive disorder: Results from the OCD Collaborative Genetics Study. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 165: 326-36. PMID 24798771 DOI: 10.1002/ajmg.b.32235  1
2014 Sakakibara Y, Kasahara Y, Hall FS, Lesch KP, Murphy DL, Uhl GR, Sora I. Developmental alterations in anxiety and cognitive behavior in serotonin transporter mutant mice. Psychopharmacology. 231: 4119-33. PMID 24728652 DOI: 10.1007/s00213-014-3554-x  1
2014 Rudnick G, Krämer R, Blakely RD, Murphy DL, Verrey F. The SLC6 transporters: perspectives on structure, functions, regulation, and models for transporter dysfunction. PflüGers Archiv : European Journal of Physiology. 466: 25-42. PMID 24337881 DOI: 10.1007/s00424-013-1410-1  1
2014 Timpano KR, Çek D, Rubenstein LM, Murphy D, Schmidt NB. Exploring the association between obsessive-compulsive symptoms and loneliness: Consideration of specificity and gender Journal of Cognitive Psychotherapy. 28: 264-273. DOI: 10.1891/0889-8391.28.4.264  1
2013 Davis LK, Yu D, Keenan CL, Gamazon ER, Konkashbaev AI, Derks EM, Neale BM, Yang J, Lee SH, Evans P, Barr CL, Bellodi L, Benarroch F, Berrio GB, Bienvenu OJ, ... ... Murphy DL, et al. Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. Plos Genetics. 9: e1003864. PMID 24204291 DOI: 10.1371/journal.pgen.1003864  1
2013 Ozomaro U, Cai G, Kajiwara Y, Yoon S, Makarov V, Delorme R, Betancur C, Ruhrmann S, Falkai P, Grabe HJ, Maier W, Wagner M, Lennertz L, Moessner R, Murphy DL, et al. Characterization of SLITRK1 variation in obsessive-compulsive disorder. Plos One. 8: e70376. PMID 23990902 DOI: 10.1371/journal.pone.0070376  1
2013 Moya PR, Wendland JR, Rubenstein LM, Timpano KR, Heiman GA, Tischfield JA, King RA, Andrews AM, Ramamoorthy S, McMahon FJ, Murphy DL. Common and rare alleles of the serotonin transporter gene, SLC6A4, associated with Tourette's disorder. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 1263-70. PMID 23630162 DOI: 10.1002/mds.25460  1
2013 Stewart SE, Mayerfeld C, Arnold PD, Crane JR, O'Dushlaine C, Fagerness JA, Yu D, Scharf JM, Chan E, Kassam F, Moya PR, Wendland JR, Delorme R, Richter MA, Kennedy JL, ... ... Murphy DL, et al. Meta-analysis of association between obsessive-compulsive disorder and the 3' region of neuronal glutamate transporter gene SLC1A1. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 162: 367-79. PMID 23606572 DOI: 10.1002/ajmg.b.32137  1
2013 Murphy DL, Moya PR, Fox MA, Rubenstein LM, Wendland JR, Timpano KR. Anxiety and affective disorder comorbidity related to serotonin and other neurotransmitter systems: obsessive-compulsive disorder as an example of overlapping clinical and genetic heterogeneity. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20120435. PMID 23440468 DOI: 10.1098/rstb.2012.0435  1
2013 Fox MA, Panessiti MG, Hall FS, Uhl GR, Murphy DL. An evaluation of the serotonin system and perseverative, compulsive, stereotypical, and hyperactive behaviors in dopamine transporter (DAT) knockout mice. Psychopharmacology. 227: 685-95. PMID 23417514 DOI: 10.1007/s00213-013-2988-x  1
2013 Murphy DL, Maile MS, Vogt NM. 5HTTLPR: White Knight or Dark Blight? Acs Chemical Neuroscience. 4: 13-5. PMID 23336038 DOI: 10.1021/cn3002224  1
2013 Greenwood TA, Kelsoe JR. Genome-wide association study of irritable vs. elated mania suggests genetic differences between clinical subtypes of bipolar disorder. Plos One. 8: e53804. PMID 23326512 DOI: 10.1371/journal.pone.0053804  0.52
2013 Fox MA, Panessiti MG, Moya PR, Tolliver TJ, Chen K, Shih JC, Murphy DL. Mutations in monoamine oxidase (MAO) genes in mice lead to hypersensitivity to serotonin-enhancing drugs: implications for drug side effects in humans. The Pharmacogenomics Journal. 13: 551-7. PMID 22964922 DOI: 10.1038/tpj.2012.35  1
2013 Stewart SE, Yu D, Scharf JM, Neale BM, Fagerness JA, Mathews CA, Arnold PD, Evans PD, Gamazon ER, Davis LK, Osiecki L, McGrath L, Haddad S, Crane J, Hezel D, ... ... Murphy DL, et al. Genome-wide association study of obsessive-compulsive disorder. Molecular Psychiatry. 18: 788-98. PMID 22889921 DOI: 10.1038/mp.2012.85  1
2013 Moya PR, Wendland JR, Salemme J, Fried RL, Murphy DL. miR-15a and miR-16 regulate serotonin transporter expression in human placental and rat brain raphe cells. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 621-9. PMID 22564678 DOI: 10.1017/S1461145712000454  1
2012 Nissen S, Liang S, Shehktman T, Kelsoe JR, Greenwood TA, Nievergelt CM, McKinney R, Shilling PD, Smith EN, Schork NJ, Bloss CS, Nurnberger JI, Edenberg HJ, Foroud T, et al. Evidence for association of bipolar disorder to haplotypes in the 22q12.3 region near the genes stargazin, IFT27 and parvalbumin. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 941-50. PMID 23038240 DOI: 10.1002/ajmg.b.32099  0.52
2012 Lerner A, Bagic A, Simmons JM, Mari Z, Bonne O, Xu B, Kazuba D, Herscovitch P, Carson RE, Murphy DL, Drevets WC, Hallett M. Widespread abnormality of the γ-aminobutyric acid-ergic system in Tourette syndrome. Brain : a Journal of Neurology. 135: 1926-36. PMID 22577221 DOI: 10.1093/brain/aws104  1
2012 Timpano KR, Rubenstein LM, Murphy DL. Phenomenological features and clinical impact of affective disorders in OCD: a focus on the bipolar disorder and OCD connection. Depression and Anxiety. 29: 226-33. PMID 22109969 DOI: 10.1002/da.20908  1
2012 Nestadt G, Wang Y, Grados MA, Riddle MA, Greenberg BD, Knowles JA, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Piacentini J, Geller D, Pauls D, et al. Homeobox genes in obsessive-compulsive disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 53-60. PMID 22095678 DOI: 10.1002/ajmg.b.32001  1
2012 Bienvenu OJ, Samuels JF, Wuyek LA, Liang KY, Wang Y, Grados MA, Cullen BA, Riddle MA, Greenberg BD, Rasmussen SA, Fyer AJ, Pinto A, Rauch SL, Pauls DL, McCracken JT, ... ... Murphy DL, et al. Is obsessive-compulsive disorder an anxiety disorder, and what, if any, are spectrum conditions? A family study perspective. Psychological Medicine. 42: 1-13. PMID 21733222 DOI: 10.1017/S0033291711000742  1
2012 Guiard BP, Mansari ME, Murphy DL, Blier P. Altered response to the selective serotonin reuptake inhibitor escitalopram in mice heterozygous for the serotonin transporter: an electrophysiological and neurochemical study. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 349-61. PMID 21439106 DOI: 10.1017/S1461145711000484  1
2012 Willour VL, Seifuddin F, Mahon PB, Jancic D, Pirooznia M, Steele J, Schweizer B, Goes FS, Mondimore FM, Mackinnon DF, Perlis RH, Lee PH, Huang J, Kelsoe JR, et al. A genome-wide association study of attempted suicide. Molecular Psychiatry. 17: 433-44. PMID 21423239 DOI: 10.1038/mp.2011.4  0.52
2012 Murphy DL. An overview of serotonin neurochemistry and neuroanatomy 5-Hydroxytryptamine in Psychiatry: a Spectrum of Ideas. DOI: 10.1093/acprof:oso/9780192620118.003.0003  1
2011 Hagino Y, Takamatsu Y, Yamamoto H, Iwamura T, Murphy DL, Uhl GR, Sora I, Ikeda K. Effects of MDMA on Extracellular Dopamine and Serotonin Levels in Mice Lacking Dopamine and/or Serotonin Transporters. Current Neuropharmacology. 9: 91-5. PMID 21886569 DOI: 10.2174/157015911795017254  1
2011 Timpano KR, Schmidt NB, Wheaton MG, Wendland JR, Murphy DL. Consideration of the BDNF gene in relation to two phenotypes: hoarding and obesity. Journal of Abnormal Psychology. 120: 700-7. PMID 21668081 DOI: 10.1037/a0024159  1
2011 Moya PR, Fox MA, Jensen CL, Laporte JL, French HT, Wendland JR, Murphy DL. Altered 5-HT2C receptor agonist-induced responses and 5-HT2C receptor RNA editing in the amygdala of serotonin transporter knockout mice. Bmc Pharmacology. 11: 3. PMID 21473759 DOI: 10.1186/1471-2210-11-3  1
2011 Samuels J, Wang Y, Riddle MA, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Grados MA, Knowles JA, Piacentini J, Cullen B, Bienvenu OJ, Rasmussen SA, Geller D, et al. Comprehensive family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 472-7. PMID 21445956 DOI: 10.1002/ajmg.b.31184  1
2011 Murphy DL, Moya PR. Human serotonin transporter gene (SLC6A4) variants: their contributions to understanding pharmacogenomic and other functional G×G and G×E differences in health and disease. Current Opinion in Pharmacology. 11: 3-10. PMID 21439906 DOI: 10.1016/j.coph.2011.02.008  1
2011 Mroczkowski MM, Goes FS, Riddle MA, Grados MA, Bienvenu OJ, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Knowles JA, Piacentini J, Cullen B, Rasmussen SA, Geller DA, et al. Separation anxiety disorder in OCD. Depression and Anxiety. 28: 256-62. PMID 21308883 DOI: 10.1002/da.20773  1
2011 Belmonte Mahon P, Pirooznia M, Goes FS, Seifuddin F, Steele J, Lee PH, Huang J, Hamshere ML, Depaulo JR, Kelsoe JR, Rietschel M, Nöthen M, Cichon S, Gurling H, et al. Genome-wide association analysis of age at onset and psychotic symptoms in bipolar disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 370-8. PMID 21305692 DOI: 10.1002/ajmg.b.31172  0.52
2011 Hall FS, Schwarzbaum JM, Perona MT, Templin JS, Caron MG, Lesch KP, Murphy DL, Uhl GR. A greater role for the norepinephrine transporter than the serotonin transporter in murine nociception. Neuroscience. 175: 315-27. PMID 21129446 DOI: 10.1016/j.neuroscience.2010.11.057  1
2011 Voyiaziakis E, Evgrafov O, Li D, Yoon HJ, Tabares P, Samuels J, Wang Y, Riddle MA, Grados MA, Bienvenu OJ, Shugart YY, Liang KY, Greenberg BD, Rasmussen SA, Murphy DL, et al. Association of SLC6A4 variants with obsessive-compulsive disorder in a large multicenter US family study. Molecular Psychiatry. 16: 108-20. PMID 19806148 DOI: 10.1038/mp.2009.100  1
2010 Voon V, Butler TR, Ekanayake V, Gallea C, Ameli R, Murphy DL, Hallett M. Psychiatric symptoms associated with focal hand dystonia. Movement Disorders : Official Journal of the Movement Disorder Society. 25: 2249-52. PMID 20737548 DOI: 10.1002/mds.23250  1
2010 Murphy DL, Timpano KR, Wheaton MG, Greenberg BD, Miguel EC. Obsessive-compulsive disorder and its related disorders: a reappraisal of obsessive-compulsive spectrum concepts. Dialogues in Clinical Neuroscience. 12: 131-48. PMID 20623919  1
2010 Moya PR, Murphy DL, McMahon FJ, Wendland JR. Increased gene expression of diacylglycerol kinase η in bipolar disorder. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 13: 1127-8. PMID 20519059 DOI: 10.1017/S1461145710000593  1
2010 Correia S, Hubbard E, Hassenstab J, Yip A, Vymazal J, Herynek V, Giedd J, Murphy DL, Greenberg BD. Basal ganglia MR relaxometry in obsessive-compulsive disorder: T2 depends upon age of symptom onset. Brain Imaging and Behavior. 4: 35-45. PMID 20503112 DOI: 10.1007/s11682-009-9083-2  1
2010 Fox MA, Stein AR, French HT, Murphy DL. Functional interactions between 5-HT2A and presynaptic 5-HT1A receptor-based responses in mice genetically deficient in the serotonin 5-HT transporter (SERT). British Journal of Pharmacology. 159: 879-87. PMID 20128812 DOI: 10.1111/j.1476-5381.2009.00578.x  1
2010 Brigman JL, Mathur P, Harvey-White J, Izquierdo A, Saksida LM, Bussey TJ, Fox S, Deneris E, Murphy DL, Holmes A. Pharmacological or genetic inactivation of the serotonin transporter improves reversal learning in mice. Cerebral Cortex (New York, N.Y. : 1991). 20: 1955-63. PMID 20032063 DOI: 10.1093/cercor/bhp266  1
2010 Fox MA, French HT, LaPorte JL, Blackler AR, Murphy DL. The serotonin 5-HT(2A) receptor agonist TCB-2: a behavioral and neurophysiological analysis. Psychopharmacology. 212: 13-23. PMID 19823806 DOI: 10.1007/s00213-009-1694-1  1
2010 Wang Y, Adamczyk A, Shugart YY, Samuels JF, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Pinto A, Fyer AJ, Piacentini J, et al. A screen of SLC1A1 for OCD-related alleles. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 675-9. PMID 19569082 DOI: 10.1002/ajmg.b.31001  1
2010 Laporte JL, Ren-Patterson RF, Murphy DL, Kalueff AV. Modeling SERT × BDNF interactions in brain disorders: Single BDNF gene allele exacerbates brain monoamine deficiencies and increases stress abnormalities in serotonin transporter knock-out mice Experimental Models in Serotonin Transporter Research. 270-287. DOI: 10.1017/CBO9780511729935.010  1
2009 Cyphert JM, Kovarova M, Allen IC, Hartney JM, Murphy DL, Wess J, Koller BH. Cooperation between mast cells and neurons is essential for antigen-mediated bronchoconstriction. Journal of Immunology (Baltimore, Md. : 1950). 182: 7430-9. PMID 19494266 DOI: 10.4049/jimmunol.0900039  1
2009 Pinto A, Greenberg BD, Murphy DL, Nestadt G, Rasmussen SA. Using individual items to clarify OCD symptom structure: the case for five factors. The American Journal of Psychiatry. 166: 728-9; author reply . PMID 19487406 DOI: 10.1176/appi.ajp.2009.09020287  1
2009 Hall FS, Li XF, Randall-Thompson J, Sora I, Murphy DL, Lesch KP, Caron M, Uhl GR. Cocaine-conditioned locomotion in dopamine transporter, norepinephrine transporter and 5-HT transporter knockout mice. Neuroscience. 162: 870-80. PMID 19482066 DOI: 10.1016/j.neuroscience.2009.05.058  1
2009 Wendland JR, Moya PR, Timpano KR, Anavitarte AP, Kruse MR, Wheaton MG, Ren-Patterson RF, Murphy DL. A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder. Archives of General Psychiatry. 66: 408-16. PMID 19349310 DOI: 10.1001/archgenpsychiatry.2009.6  1
2009 Fox MA, Jensen CL, Murphy DL. Tramadol and another atypical opioid meperidine have exaggerated serotonin syndrome behavioural effects, but decreased analgesic effects, in genetically deficient serotonin transporter (SERT) mice. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 1055-65. PMID 19275775 DOI: 10.1017/S146114570900011X  1
2009 Grover D, Verma R, Goes FS, Mahon PL, Gershon ES, McMahon FJ, Potash JB, Gershon ES, McMahon FJ, Potash JB. Family-based association of YWHAH in psychotic bipolar disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 977-83. PMID 19160447 DOI: 10.1002/ajmg.b.30927  1
2009 Shugart YY, Wang Y, Samuels JF, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Hoehn-Saric R, Pinto A, Fyer AJ, Piacentini J, et al. A family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder in 378 families. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 886-92. PMID 19152386 DOI: 10.1002/ajmg.b.30914  1
2009 Basselin M, Fox MA, Chang L, Bell JM, Greenstein D, Chen M, Murphy DL, Rapoport SI. Imaging elevated brain arachidonic acid signaling in unanesthetized serotonin transporter (5-HTT)-deficient mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1695-709. PMID 19145225 DOI: 10.1038/npp.2008.227  1
2009 Timpano KR, Buckner JD, Richey JA, Murphy DL, Schmidt NB. Exploration of anxiety sensitivity and distress tolerance as vulnerability factors for hoarding behaviors. Depression and Anxiety. 26: 343-53. PMID 19123454 DOI: 10.1002/da.20469  1
2009 Züchner S, Wendland JR, Ashley-Koch AE, Collins AL, Tran-Viet KN, Quinn K, Timpano KC, Cuccaro ML, Pericak-Vance MA, Steffens DC, Krishnan KR, Feng G, Murphy DL. Multiple rare SAPAP3 missense variants in trichotillomania and OCD. Molecular Psychiatry. 14: 6-9. PMID 19096451 DOI: 10.1038/mp.2008.83  1
2009 Bischoff SC, Mailer R, Pabst O, Weier G, Sedlik W, Li Z, Chen JJ, Murphy DL, Gershon MD. Role of serotonin in intestinal inflammation: knockout of serotonin reuptake transporter exacerbates 2,4,6-trinitrobenzene sulfonic acid colitis in mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 296: G685-95. PMID 19095763 DOI: 10.1152/ajpgi.90685.2008  1
2009 Bienvenu OJ, Wang Y, Shugart YY, Welch JM, Grados MA, Fyer AJ, Rauch SL, McCracken JT, Rasmussen SA, Murphy DL, Cullen B, Valle D, Hoehn-Saric R, Greenberg BD, Pinto A, et al. Sapap3 and pathological grooming in humans: Results from the OCD collaborative genetics study. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 710-20. PMID 19051237 DOI: 10.1002/ajmg.b.30897  1
2009 Nestadt G, Di CZ, Riddle MA, Grados MA, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Pinto A, Knowles JA, Piacentini J, Pauls DL, et al. Obsessive-compulsive disorder: subclassification based on co-morbidity. Psychological Medicine. 39: 1491-501. PMID 19046474 DOI: 10.1017/S0033291708004753  1
2009 Moy SS, Nadler JJ, Young NB, Nonneman RJ, Grossman AW, Murphy DL, D'Ercole AJ, Crawley JN, Magnuson TR, Lauder JM. Social approach in genetically engineered mouse lines relevant to autism. Genes, Brain, and Behavior. 8: 129-42. PMID 19016890 DOI: 10.1111/j.1601-183X.2008.00452.x  1
2009 Lerner A, Bagic A, Hanakawa T, Boudreau EA, Pagan F, Mari Z, Bara-Jimenez W, Aksu M, Sato S, Murphy DL, Hallett M. Involvement of insula and cingulate cortices in control and suppression of natural urges. Cerebral Cortex (New York, N.Y. : 1991). 19: 218-23. PMID 18469316 DOI: 10.1093/cercor/bhn074  1
2009 Wang Y, Samuels JF, Chang YC, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Hoehn-Saric R, Pinto A, Fyer AJ, Piacentini J, et al. Gender differences in genetic linkage and association on 11p15 in obsessive-compulsive disorder families. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 33-40. PMID 18425788 DOI: 10.1002/ajmg.b.30760  1
2009 Willour VL, Chen H, Toolan J, Belmonte P, Cutler DJ, Goes FS, Zandi PP, Lee RS, MacKinnon DF, Mondimore FM, Schweizer B, DePaulo JR, Gershon ES, et al. Family-based association of FKBP5 in bipolar disorder. Molecular Psychiatry. 14: 261-8. PMID 18180755 DOI: 10.1038/sj.mp.4002141  1
2009 Kalueff AV, Ren-Patterson RF, LaPorte JL, Murphy DL. Domain-oriented analysis for understanding molecular interactions and translating animal genetic models into neuropsychiatric disorders: Focus on serotonin transporter and BDNF Animal Genetics. 197-220.  1
2008 Liu L, Foroud T, Xuei X, Berrettini W, Byerley W, Coryell W, El-Mallakh R, Gershon ES, Kelsoe JR, Lawson WB, MacKinnon DF, McInnis M, McMahon FJ, Murphy DL, Rice J, et al. Evidence of association between brain-derived neurotrophic factor gene and bipolar disorder. Psychiatric Genetics. 18: 267-74. PMID 19018231 DOI: 10.1097/YPG.0b013e3283060f59  1
2008 Murphy DL, Fox MA, Timpano KR, Moya PR, Ren-Patterson R, Andrews AM, Holmes A, Lesch KP, Wendland JR. How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems. Neuropharmacology. 55: 932-60. PMID 18824000 DOI: 10.1016/j.neuropharm.2008.08.034  1
2008 Schooler C, Revell AJ, Timpano KR, Wheaton M, Murphy DL. Predicting genetic loading from symptom patterns in obsessive- compulsive disorder: a latent variable analysis. Depression and Anxiety. 25: 680-8. PMID 18729144 DOI: 10.1002/da.20444  1
2008 Fox MA, Jensen CL, French HT, Stein AR, Huang SJ, Tolliver TJ, Murphy DL. Neurochemical, behavioral, and physiological effects of pharmacologically enhanced serotonin levels in serotonin transporter (SERT)-deficient mice. Psychopharmacology. 201: 203-18. PMID 18712364 DOI: 10.1007/s00213-008-1268-7  1
2008 Samuels JF, Bienvenu OJ, Pinto A, Murphy DL, Piacentini J, Rauch SL, Fyer AJ, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Cullen B, Riddle MA, Rasmussen SA, Pauls DL, et al. Sex-specific clinical correlates of hoarding in obsessive-compulsive disorder. Behaviour Research and Therapy. 46: 1040-6. PMID 18692168 DOI: 10.1016/j.brat.2008.06.005  1
2008 Perona MT, Waters S, Hall FS, Sora I, Lesch KP, Murphy DL, Caron M, Uhl GR. Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: prominent effects of dopamine transporter deletions. Behavioural Pharmacology. 19: 566-74. PMID 18690111 DOI: 10.1097/FBP.0b013e32830cd80f  1
2008 Laporte JL, Ren-Patterson RF, Murphy DL, Kalueff AV. Refining psychiatric genetics: from 'mouse psychiatry' to understanding complex human disorders. Behavioural Pharmacology. 19: 377-84. PMID 18690099 DOI: 10.1097/FBP.0b013e32830dc09b  1
2008 Ross J, Berrettini W, Coryell W, Gershon ES, Badner JA, Kelsoe JR, McInnis MG, McMahon FJ, Murphy DL, Nurnberger JI, Foroud T, Rice JP, Scheftner WB, Zandi P, Edenberg H, et al. Genome-wide parametric linkage analyses of 644 bipolar pedigrees suggest susceptibility loci at chromosomes 16 and 20. Psychiatric Genetics. 18: 191-8. PMID 18628681 DOI: 10.1097/YPG.0b013e3283050aa5  1
2008 Zandi PP, Belmonte PL, Willour VL, Goes FS, Badner JA, Simpson SG, Gershon ES, McMahon FJ, DePaulo JR, Potash JB. Association study of Wnt signaling pathway genes in bipolar disorder. Archives of General Psychiatry. 65: 785-93. PMID 18606951 DOI: 10.1001/archpsyc.65.7.785  0.52
2008 Ni W, Zhou H, Diaz J, Murphy DL, Haywood JR, Watts SW. Lack of the serotonin transporter does not prevent mineralocorticoid hypertension in rat and mouse. European Journal of Pharmacology. 589: 225-7. PMID 18573249 DOI: 10.1016/j.ejphar.2008.06.012  1
2008 Pinto A, Greenberg BD, Grados MA, Bienvenu OJ, Samuels JF, Murphy DL, Hasler G, Stout RL, Rauch SL, Shugart YY, Pauls DL, Knowles JA, Fyer AJ, McCracken JT, Piacentini J, et al. Further development of YBOCS dimensions in the OCD Collaborative Genetics study: symptoms vs. categories. Psychiatry Research. 160: 83-93. PMID 18514325 DOI: 10.1016/j.psychres.2007.07.010  1
2008 Carneiro AM, Cook EH, Murphy DL, Blakely RD. Interactions between integrin alphaIIbbeta3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans. The Journal of Clinical Investigation. 118: 1544-52. PMID 18317590 DOI: 10.1172/JCI33374  1
2008 Liang KY, Wang Y, Shugart YY, Grados M, Fyer AJ, Rauch S, Murphy D, McCracken J, Rasmussen S, Cullen B, Hoehn-Saric R, Greenberg B, Pinto A, Knowles J, Piacentini J, et al. Evidence for potential relationship between SLC1A1 and a putative genetic linkage region on chromosome 14q to obsessive-compulsive disorder with compulsive hoarding. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 1000-2. PMID 18286588 DOI: 10.1002/ajmg.b.30713  1
2008 Kalueff AV, LaPorte JL, Murphy DL, Sufka K. Hybridizing behavioral models: a possible solution to some problems in neurophenotyping research? Progress in Neuro-Psychopharmacology & Biological Psychiatry. 32: 1172-8. PMID 18222590 DOI: 10.1016/j.pnpbp.2007.12.010  1
2008 Murphy DL, Lesch KP. Targeting the murine serotonin transporter: insights into human neurobiology. Nature Reviews. Neuroscience. 9: 85-96. PMID 18209729 DOI: 10.1038/nrn2284  1
2008 Wendland JR, DeGuzman TB, McMahon F, Rudnick G, Detera-Wadleigh SD, Murphy DL. SERT Ileu425Val in autism, Asperger syndrome and obsessive-compulsive disorder. Psychiatric Genetics. 18: 31-9. PMID 18197083 DOI: 10.1097/YPG.0b013e3282f08a06  1
2008 Kalueff AV, Keisala T, Minasyan A, Kumar SR, LaPorte JL, Murphy DL, Tuohimaa P. The regular and light-dark Suok tests of anxiety and sensorimotor integration: utility for behavioral characterization in laboratory rodents. Nature Protocols. 3: 129-36. PMID 18193029 DOI: 10.1038/nprot.2007.516  1
2008 Kalueff AV, Ren-Patterson RF, LaPorte JL, Murphy DL. Domain interplay concept in animal models of neuropsychiatric disorders: a new strategy for high-throughput neurophenotyping research. Behavioural Brain Research. 188: 243-9. PMID 18164476 DOI: 10.1016/j.bbr.2007.11.011  1
2008 Wendland JR, Moya PR, Kruse MR, Ren-Patterson RF, Jensen CL, Timpano KR, Murphy DL. A novel, putative gain-of-function haplotype at SLC6A4 associates with obsessive-compulsive disorder. Human Molecular Genetics. 17: 717-23. PMID 18055562 DOI: 10.1093/hmg/ddm343  1
2008 Kalueff AV, LaPorte JL, Murphy DL. Perspectives on genetic animal models of serotonin toxicity. Neurochemistry International. 52: 649-58. PMID 17935833 DOI: 10.1016/j.neuint.2007.08.015  1
2008 Cullen B, Samuels JF, Pinto A, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Greenberg BD, Knowles JA, Piacentini J, Bienvenu OJ, Grados MA, Riddle MA, Rasmussen SA, Pauls DL, et al. Demographic and clinical characteristics associated with treatment status in family members with obsessive-compulsive disorder. Depression and Anxiety. 25: 218-24. PMID 17345603 DOI: 10.1002/da.20293  1
2008 Wheaton M, Timpano KR, LaSalle-Ricci VH, Murphy D. Characterizing the hoarding phenotype in individuals with OCD: Associations with comorbidity, severity and gender Journal of Anxiety Disorders. 22: 243-252. PMID 17339096 DOI: 10.1016/j.janxdis.2007.01.015  1
2008 Wendland JR, Kruse MR, Cromer KR, Murphy DL. A large case-control study of common functional SLC6A4 and BDNF variants in obsessive-compulsive disorder (Neuropsychopharmacology (March 21, 2007) DOI: 10.1038/sj.npp.1301394) Neuropsychopharmacology. 33: 1476. DOI: 10.1038/sj.npp.1301515  1
2007 Kalueff AV, Murphy DL. The importance of cognitive phenotypes in experimental modeling of animal anxiety and depression. Neural Plasticity. 2007: 52087. PMID 18288249 DOI: 10.1155/2007/52087  1
2007 Kalueff AV, Aldridge JW, LaPorte JL, Murphy DL, Tuohimaa P. Analyzing grooming microstructure in neurobehavioral experiments. Nature Protocols. 2: 2538-44. PMID 17947996 DOI: 10.1038/nprot.2007.367  1
2007 Fox MA, Jensen CL, Gallagher PS, Murphy DL. Receptor mediation of exaggerated responses to serotonin-enhancing drugs in serotonin transporter (SERT)-deficient mice. Neuropharmacology. 53: 643-56. PMID 17765930 DOI: 10.1016/j.neuropharm.2007.07.009  1
2007 Fox MA, Andrews AM, Wendland JR, Lesch KP, Holmes A, Murphy DL. A pharmacological analysis of mice with a targeted disruption of the serotonin transporter. Psychopharmacology. 195: 147-66. PMID 17712549 DOI: 10.1007/s00213-007-0910-0  1
2007 Kalueff AV, Jensen CL, Murphy DL. Locomotory patterns, spatiotemporal organization of exploration and spatial memory in serotonin transporter knockout mice. Brain Research. 1169: 87-97. PMID 17692295 DOI: 10.1016/j.brainres.2007.07.009  1
2007 Numachi Y, Ohara A, Yamashita M, Fukushima S, Kobayashi H, Hata H, Watanabe H, Hall FS, Lesch KP, Murphy DL, Uhl GR, Sora I. Methamphetamine-induced hyperthermia and lethal toxicity: role of the dopamine and serotonin transporters. European Journal of Pharmacology. 572: 120-8. PMID 17673199 DOI: 10.1016/j.ejphar.2007.06.022  1
2007 Cromer KR, Schmidt NB, Murphy DL. Do traumatic events influence the clinical expression of compulsive hoarding? Behaviour Research and Therapy. 45: 2581-92. PMID 17673166 DOI: 10.1016/j.brat.2007.06.005  1
2007 Lerner A, Bagic A, Boudreau EA, Hanakawa T, Pagan F, Mari Z, Bara-Jimenez W, Aksu M, Garraux G, Simmons JM, Sato S, Murphy DL, Hallett M. Neuroimaging of neuronal circuits involved in tic generation in patients with Tourette syndrome. Neurology. 68: 1979-87. PMID 17548547 DOI: 10.1212/01.wnl.0000264417.18604.12  1
2007 Schmitt A, Benninghoff J, Moessner R, Rizzi M, Paizanis E, Doenitz C, Gross S, Hermann M, Gritti A, Lanfumey L, Fritzen S, Reif A, Hamon M, Murphy DL, Vescovi A, et al. Adult neurogenesis in serotonin transporter deficient mice. Journal of Neural Transmission (Vienna, Austria : 1996). 114: 1107-19. PMID 17510734 DOI: 10.1007/s00702-007-0724-6  1
2007 Grados MA, Samuels J, Shugart YY, Willour VL, Wang Y, Cullen B, Bienvenu OJ, Hoehn-Saric R, Valle D, Liang KY, Riddle MA, Wendland JR, Murphy DL, Nestadt G, Detera-Wadleigh S. Rare plus common SERT variants in obsessive-compulsive disorder. Molecular Psychiatry. 12: 422-3. PMID 17453059 DOI: 10.1038/sj.mp.4001970  1
2007 Wendland JR, Kruse MR, Cromer KR, Cromer KC, Murphy DL. A large case-control study of common functional SLC6A4 and BDNF variants in obsessive-compulsive disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 2543-51. PMID 17375136 DOI: 10.1038/sj.npp.1301394  1
2007 Samuels J, Shugart YY, Grados MA, Willour VL, Bienvenu OJ, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Wang Y, Pinto A, Fyer AJ, Piacentini J, Pauls DL, et al. Significant linkage to compulsive hoarding on chromosome 14 in families with obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study. The American Journal of Psychiatry. 164: 493-9. PMID 17329475 DOI: 10.1176/appi.ajp.164.3.493  1
2007 Kalueff AV, Wheaton M, Murphy DL. What's wrong with my mouse model? Advances and strategies in animal modeling of anxiety and depression. Behavioural Brain Research. 179: 1-18. PMID 17306892 DOI: 10.1016/j.bbr.2007.01.023  1
2007 Kalueff AV, Ren-Patterson RF, Murphy DL. The developing use of heterozygous mutant mouse models in brain monoamine transporter research. Trends in Pharmacological Sciences. 28: 122-7. PMID 17275930 DOI: 10.1016/j.tips.2007.01.002  1
2007 Goes FS, Zandi PP, Miao K, McMahon FJ, Steele J, Willour VL, Mackinnon DF, Mondimore FM, Schweizer B, Nurnberger JI, Rice JP, Scheftner W, Coryell W, Berrettini WH, Kelsoe JR, ... ... Murphy DL, et al. Mood-incongruent psychotic features in bipolar disorder: familial aggregation and suggestive linkage to 2p11-q14 and 13q21-33. The American Journal of Psychiatry. 164: 236-47. PMID 17267786 DOI: 10.1176/appi.ajp.164.2.236  1
2007 Wellman CL, Izquierdo A, Garrett JE, Martin KP, Carroll J, Millstein R, Lesch KP, Murphy DL, Holmes A. Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 684-91. PMID 17234600 DOI: 10.1523/JNEUROSCI.4595-06.2007  1
2007 Carroll JC, Boyce-Rustay JM, Millstein R, Yang R, Wiedholz LM, Murphy DL, Holmes A. Effects of mild early life stress on abnormal emotion-related behaviors in 5-HTT knockout mice. Behavior Genetics. 37: 214-22. PMID 17177116 DOI: 10.1007/s10519-006-9129-9  1
2007 Cromer KR, Schmidt NB, Murphy DL. An investigation of traumatic life events and obsessive-compulsive disorder. Behaviour Research and Therapy. 45: 1683-91. PMID 17067548 DOI: 10.1016/j.brat.2006.08.018  1
2007 Hasler G, Pinto A, Greenberg BD, Samuels J, Fyer AJ, Pauls D, Knowles JA, McCracken JT, Piacentini J, Riddle MA, Rauch SL, Rasmussen SA, Willour VL, Grados MA, Cullen B, ... ... Murphy DL, et al. Familiality of factor analysis-derived YBOCS dimensions in OCD-affected sibling pairs from the OCD Collaborative Genetics Study. Biological Psychiatry. 61: 617-25. PMID 17027929 DOI: 10.1016/j.biopsych.2006.05.040  1
2007 Kalueff AV, Wheaton M, Ren-Patterson R, Murphy DL. Brain-derived neurotrophic factor, serotonin transporter, and depression: comment on Kaufman et al. Biological Psychiatry. 61: 1112-3; author reply. PMID 16952335 DOI: 10.1016/j.biopsych.2006.07.001  1
2007 Kalueff AV, Fox MA, Gallagher PS, Murphy DL. Hypolocomotion, anxiety and serotonin syndrome-like behavior contribute to the complex phenotype of serotonin transporter knockout mice. Genes, Brain, and Behavior. 6: 389-400. PMID 16939636 DOI: 10.1111/j.1601-183X.2006.00270.x  1
2007 Altamura C, Dell'Acqua ML, Moessner R, Murphy DL, Lesch KP, Persico AM. Altered neocortical cell density and layer thickness in serotonin transporter knockout mice: a quantitation study. Cerebral Cortex (New York, N.Y. : 1991). 17: 1394-401. PMID 16905592 DOI: 10.1093/cercor/bhl051  1
2007 Samuels JF, Bienvenu OJ, Pinto A, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Grados MA, Greenberg BD, Knowles JA, Piacentini J, Cannistraro PA, Cullen B, Riddle MA, Rasmussen SA, et al. Hoarding in obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study. Behaviour Research and Therapy. 45: 673-86. PMID 16824483 DOI: 10.1016/j.brat.2006.05.008  1
2006 Boyce-Rustay JM, Wiedholz LM, Millstein RA, Carroll J, Murphy DL, Daws LC, Holmes A. Ethanol-related behaviors in serotonin transporter knockout mice. Alcoholism, Clinical and Experimental Research. 30: 1957-65. PMID 17117959 DOI: 10.1111/j.1530-0277.2006.00241.x  1
2006 Chotai J, Murphy DL, Constantino JN. Cerebrospinal fluid monoamine metabolite levels in human newborn infants born in winter differ from those born in summer. Psychiatry Research. 145: 189-97. PMID 17074397 DOI: 10.1016/j.psychres.2005.11.008  1
2006 Ren-Patterson RF, Cochran LW, Holmes A, Lesch KP, Lu B, Murphy DL. Gender-dependent modulation of brain monoamines and anxiety-like behaviors in mice with genetic serotonin transporter and BDNF deficiencies. Cellular and Molecular Neurobiology. 26: 755-80. PMID 17029036 DOI: 10.1007/s10571-006-9048-6  1
2006 Kalueff AV, Gallagher PS, Murphy DL. Are serotonin transporter knockout mice 'depressed'?: hypoactivity but no anhedonia. Neuroreport. 17: 1347-51. PMID 16951583 DOI: 10.1097/01.wnr.0000230514.08962.76  1
2006 Wendland JR, Kruse MR, Murphy DL. Functional SLITRK1 var321, varCDfs and SLC6A4 G56A variants and susceptibility to obsessive-compulsive disorder. Molecular Psychiatry. 11: 802-4. PMID 16936762 DOI: 10.1038/sj.mp.4001848  1
2006 Kalueff AV, Avgustinovich DF, Kudryavtseva NN, Murphy DL. BDNF in anxiety and depression. Science (New York, N.Y.). 312: 1598-9; author reply. PMID 16778038 DOI: 10.1126/science.312.5780.1598  1
2006 Daws LC, Montañez S, Munn JL, Owens WA, Baganz NL, Boyce-Rustay JM, Millstein RA, Wiedholz LM, Murphy DL, Holmes A. Ethanol inhibits clearance of brain serotonin by a serotonin transporter-independent mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6431-8. PMID 16775130 DOI: 10.1523/JNEUROSCI.4050-05.2006  1
2006 Shugart YY, Samuels J, Willour VL, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Wang Y, Pinto A, Fyer AJ, Piacentini J, Pauls DL, Cullen B, et al. Genomewide linkage scan for obsessive-compulsive disorder: evidence for susceptibility loci on chromosomes 3q, 7p, 1q, 15q, and 6q. Molecular Psychiatry. 11: 763-70. PMID 16755275 DOI: 10.1038/sj.mp.4001847  1
2006 Hu XZ, Lipsky RH, Zhu G, Akhtar LA, Taubman J, Greenberg BD, Xu K, Arnold PD, Richter MA, Kennedy JL, Murphy DL, Goldman D. Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. American Journal of Human Genetics. 78: 815-26. PMID 16642437 DOI: 10.1086/503850  1
2006 Hasler G, Kazuba D, Murphy DL. Factor analysis of obsessive-compulsive disorder YBOCS-SC symptoms and association with 5-HTTLPR SERT polymorphism. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 403-8. PMID 16583440 DOI: 10.1002/ajmg.b.30309  1
2006 Adamec R, Burton P, Blundell J, Murphy DL, Holmes A. Vulnerability to mild predator stress in serotonin transporter knockout mice. Behavioural Brain Research. 170: 126-40. PMID 16546269 DOI: 10.1016/j.bbr.2006.02.012  1
2006 Zhao S, Edwards J, Carroll J, Wiedholz L, Millstein RA, Jaing C, Murphy DL, Lanthorn TH, Holmes A. Insertion mutation at the C-terminus of the serotonin transporter disrupts brain serotonin function and emotion-related behaviors in mice. Neuroscience. 140: 321-34. PMID 16542782 DOI: 10.1016/j.neuroscience.2006.01.049  1
2006 Samuels JF, Riddle MA, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Grados MA, Pinto A, Knowles JA, Piacentini J, Cannistraro PA, Cullen B, Bienvenu OJ, Rasmussen SA, et al. The OCD collaborative genetics study: methods and sample description. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 201-7. PMID 16511842 DOI: 10.1002/ajmg.b.30224  1
2006 Wendland JR, Martin BJ, Kruse MR, Lesch KP, Murphy DL. Simultaneous genotyping of four functional loci of human SLC6A4, with a reappraisal of 5-HTTLPR and rs25531. Molecular Psychiatry. 11: 224-6. PMID 16402131 DOI: 10.1038/sj.mp.4001789  1
2006 LaSalle-Ricci VH, Arnkoff DB, Glass CR, Crawley SA, Ronquillo JG, Murphy DL. The hoarding dimension of OCD: psychological comorbidity and the five-factor personality model. Behaviour Research and Therapy. 44: 1503-12. PMID 16386705 DOI: 10.1016/j.brat.2005.11.009  1
2005 Kim DK, Tolliver TJ, Huang SJ, Martin BJ, Andrews AM, Wichems C, Holmes A, Lesch KP, Murphy DL. Altered serotonin synthesis, turnover and dynamic regulation in multiple brain regions of mice lacking the serotonin transporter. Neuropharmacology. 49: 798-810. PMID 16183083 DOI: 10.1016/j.neuropharm.2005.08.010  1
2005 McQueen MB, Devlin B, Faraone SV, Nimgaonkar VL, Sklar P, Smoller JW, Abou Jamra R, Albus M, Bacanu SA, Baron M, Barrett TB, Berrettini W, Blacker D, Byerley W, Cichon S, ... ... Murphy DL, et al. Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. American Journal of Human Genetics. 77: 582-95. PMID 16175504 DOI: 10.1086/491603  1
2005 Andoh T, Chock PB, Murphy DL, Chiueh CC. Role of the redox protein thioredoxin in cytoprotective mechanism evoked by (-)-deprenyl. Molecular Pharmacology. 68: 1408-14. PMID 16099847 DOI: 10.1124/mol.105.012302  1
2005 Ren-Patterson RF, Kim DK, Zheng X, Sherrill S, Huang SJ, Tolliver T, Murphy DL. Serotonergic-like progenitor cells propagated from neural stem cells in vitro: survival with SERT protein expression following implantation into brains of mice lacking SERT. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1537-9. PMID 15972295 DOI: 10.1096/fj.04-3657fje  0.56
2005 Ni W, Wilhelm CS, Bader M, Murphy DL, Lookingland K, Watts SW. (+)-Norfenfluramine-induced arterial contraction is not dependent on endogenous 5-hydroxytryptamine or 5-hydroxytryptamine transporter. The Journal of Pharmacology and Experimental Therapeutics. 314: 953-60. PMID 15901794 DOI: 10.1124/jpet.105.087080  1
2005 Hasler G, LaSalle-Ricci VH, Ronquillo JG, Crawley SA, Cochran LW, Kazuba D, Greenberg BD, Murphy DL. Obsessive-compulsive disorder symptom dimensions show specific relationships to psychiatric comorbidity. Psychiatry Research. 135: 121-32. PMID 15893825 DOI: 10.1016/j.psychres.2005.03.003  1
2005 Esaki T, Cook M, Shimoji K, Murphy DL, Sokoloff L, Holmes A. Developmental disruption of serotonin transporter function impairs cerebral responses to whisker stimulation in mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 5582-7. PMID 15809439 DOI: 10.1073/pnas.0501509102  1
2005 Ren-Patterson RF, Cochran LW, Holmes A, Sherrill S, Huang SJ, Tolliver T, Lesch KP, Lu B, Murphy DL. Loss of brain-derived neurotrophic factor gene allele exacerbates brain monoamine deficiencies and increases stress abnormalities of serotonin transporter knockout mice. Journal of Neuroscience Research. 79: 756-71. PMID 15672416 DOI: 10.1002/jnr.20410  1
2004 Mathews TA, Fedele DE, Coppelli FM, Avila AM, Murphy DL, Andrews AM. Gene dose-dependent alterations in extraneuronal serotonin but not dopamine in mice with reduced serotonin transporter expression. Journal of Neuroscience Methods. 140: 169-81. PMID 15589347 DOI: 10.1016/j.jneumeth.2004.05.017  1
2004 Li Q, Holmes A, Ma L, Van de Kar LD, Garcia F, Murphy DL. Medial hypothalamic 5-hydroxytryptamine (5-HT)1A receptors regulate neuroendocrine responses to stress and exploratory locomotor activity: application of recombinant adenovirus containing 5-HT1A sequences. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10868-77. PMID 15574737 DOI: 10.1523/JNEUROSCI.3223-04.2004  0.4
2004 Cichon S, Buervenich S, Kirov G, Akula N, Dimitrova A, Green E, Schumacher J, Klopp N, Becker T, Ohlraun S, Schulze TG, Tullius M, Gross MM, Jones L, Krastev S, ... ... Murphy DL, et al. Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin. Nature Genetics. 36: 783-4; author reply . PMID 15284840 DOI: 10.1038/ng0804-783  1
2004 Tjurmina OA, Armando I, Saavedra JM, Li Q, Murphy DL. Life-long serotonin reuptake deficiency results in complex alterations in adrenomedullary responses to stress. Annals of the New York Academy of Sciences. 1018: 99-104. PMID 15240357 DOI: 10.1196/annals.1296.011  1
2004 Shen HW, Hagino Y, Kobayashi H, Shinohara-Tanaka K, Ikeda K, Yamamoto H, Yamamoto T, Lesch KP, Murphy DL, Hall FS, Uhl GR, Sora I. Regional differences in extracellular dopamine and serotonin assessed by in vivo microdialysis in mice lacking dopamine and/or serotonin transporters. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1790-9. PMID 15226739 DOI: 10.1038/sj.npp.1300476  1
2004 Schulze TG, Buervenich S, Badner JA, Steele CJ, Detera-Wadleigh SD, Dick D, Foroud T, Cox NJ, MacKinnon DF, Potash JB, Berrettini WH, Byerley W, Coryell W, DePaulo JR, Gershon ES, ... ... Murphy DL, et al. Loci on chromosomes 6q and 6p interact to increase susceptibility to bipolar affective disorder in the national institute of mental health genetics initiative pedigrees. Biological Psychiatry. 56: 18-23. PMID 15219468 DOI: 10.1016/j.biopsych.2004.04.004  1
2004 Murphy DL, Lerner A, Rudnick G, Lesch KP. Serotonin transporter: gene, genetic disorders, and pharmacogenetics. Molecular Interventions. 4: 109-23. PMID 15087484 DOI: 10.1124/mi.4.2.8  1
2003 Holmes A, Lit Q, Murphy DL, Gold E, Crawley JN. Abnormal anxiety-related behavior in serotonin transporter null mutant mice: the influence of genetic background. Genes, Brain, and Behavior. 2: 365-80. PMID 14653308  0.4
2003 Murphy DL, Uhl GR, Holmes A, Ren-Patterson R, Hall FS, Sora I, Detera-Wadleigh S, Lesch KP. Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders. Genes, Brain, and Behavior. 2: 350-64. PMID 14653307 DOI: 10.1046/j.1601-1848.2003.00049.x  1
2003 Holmes A, Murphy DL, Crawley JN. Abnormal behavioral phenotypes of serotonin transporter knockout mice: parallels with human anxiety and depression. Biological Psychiatry. 54: 953-9. PMID 14625137  0.4
2003 Ozaki N, Goldman D, Kaye WH, Plotnicov K, Greenberg BD, Lappalainen J, Rudnick G, Murphy DL. Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype. Molecular Psychiatry. 8: 933-6. PMID 14593431 DOI: 10.1038/sj.mp.4001365  1
2003 Armando I, Tjurmina OA, Li Q, Murphy DL, Saavedra JM. The serotonin transporter is required for stress-evoked increases in adrenal catecholamine synthesis and angiotensin II AT(2) receptor expression. Neuroendocrinology. 78: 217-25. PMID 14583654 DOI: 10.1159/000073705  1
2003 Luellen BA, Miller DB, Chisnell AC, Murphy DL, O'Callaghan JP, Andrews AM. Neuronal and astroglial responses to the serotonin and norepinephrine neurotoxin: 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine. The Journal of Pharmacology and Experimental Therapeutics. 307: 923-31. PMID 14561848 DOI: 10.1124/jpet.103.055749  1
2003 Holmes A, Yang RJ, Lesch KP, Crawley JN, Murphy DL. Mice lacking the serotonin transporter exhibit 5-HT(1A) receptor-mediated abnormalities in tests for anxiety-like behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 2077-88. PMID 12968128 DOI: 10.1038/sj.npp.1300266  0.4
2003 Kilic F, Murphy DL, Rudnick G. A human serotonin transporter mutation causes constitutive activation of transport activity. Molecular Pharmacology. 64: 440-6. PMID 12869649 DOI: 10.1124/mol.64.2.440  1
2003 Montañez S, Owens WA, Gould GG, Murphy DL, Daws LC. Exaggerated effect of fluvoxamine in heterozygote serotonin transporter knockout mice. Journal of Neurochemistry. 86: 210-9. PMID 12807440 DOI: 10.1046/j.1471-4159.2003.01836.x  1
2003 Dick DM, Foroud T, Flury L, Bowman ES, Miller MJ, Rau NL, Moe PR, Samavedy N, El-Mallakh R, Manji H, Glitz DA, Meyer ET, Smiley C, Hahn R, Widmark C, ... ... Murphy DL, et al. Genomewide linkage analyses of bipolar disorder: a new sample of 250 pedigrees from the National Institute of Mental Health Genetics Initiative. American Journal of Human Genetics. 73: 107-14. PMID 12772088 DOI: 10.1086/376562  1
2003 Persico AM, Baldi A, Dell'Acqua ML, Moessner R, Murphy DL, Lesch KP, Keller F. Reduced programmed cell death in brains of serotonin transporter knockout mice. Neuroreport. 14: 341-4. PMID 12634480 DOI: 10.1097/01.wnr.0000058244.21747.83  1
2003 Wisor JP, Wurts SW, Hall FS, Lesch KP, Murphy DL, Uhl GR, Edgar DM. Altered rapid eye movement sleep timing in serotonin transporter knockout mice. Neuroreport. 14: 233-8. PMID 12598736 DOI: 10.1097/01.wnr.0000054963.21656.bf  1
2003 Schmitt A, Mössner R, Gossmann A, Fischer IG, Gorboulev V, Murphy DL, Koepsell H, Lesch KP. Organic cation transporter capable of transporting serotonin is up-regulated in serotonin transporter-deficient mice. Journal of Neuroscience Research. 71: 701-9. PMID 12584728 DOI: 10.1002/jnr.10521  1
2003 Vogel C, Mössner R, Gerlach M, Heinemann T, Murphy DL, Riederer P, Lesch KP, Sommer C. Absence of thermal hyperalgesia in serotonin transporter-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 708-15. PMID 12533631  0.4
2002 Holmes A, Yang RJ, Murphy DL, Crawley JN. Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 914-23. PMID 12464448 DOI: 10.1016/S0893-133X(02)00374-3  0.4
2002 Tjurmina OA, Armando I, Saavedra JM, Goldstein DS, Murphy DL. Exaggerated adrenomedullary response to immobilization in mice with targeted disruption of the serotonin transporter gene. Endocrinology. 143: 4520-6. PMID 12446578 DOI: 10.1210/en.2002-220416  1
2002 Schmidt PJ, Raju J, Danaceau M, Murphy DL, Berlin RE. The effects of gender and gonadal steroids on the neuroendocrine and temperature response to m-chlorophenylpiperazine in leuprolide-induced hypogonadism in women and men. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 800-12. PMID 12431854 DOI: 10.1016/S0893-133X(02)00334-2  1
2002 Roca CA, Schmidt PJ, Smith MJ, Danaceau MA, Murphy DL, Rubinow DR. Effects of metergoline on symptoms in women with premenstrual dysphoric disorder. The American Journal of Psychiatry. 159: 1876-81. PMID 12411222 DOI: 10.1176/appi.ajp.159.11.1876  1
2002 Hall FS, Li XF, Sora I, Xu F, Caron M, Lesch KP, Murphy DL, Uhl GR. Cocaine mechanisms: enhanced cocaine, fluoxetine and nisoxetine place preferences following monoamine transporter deletions. Neuroscience. 115: 153-61. PMID 12401330 DOI: 10.1016/S0306-4522(02)00379-2  1
2002 Unger EL, Mazzola-Pomietto P, Murphy DL, Andrews AM. 2'-NH(2)-MPTP [1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine] depletes serotonin and norepinephrine in rats: a comparison with 2'-CH(3)-MPTP [1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine]. The Journal of Pharmacology and Experimental Therapeutics. 303: 527-33. PMID 12388632 DOI: 10.1124/jpet.102.037614  1
2002 Liu MT, Rayport S, Jiang Y, Murphy DL, Gershon MD. Expression and function of 5-HT3 receptors in the enteric neurons of mice lacking the serotonin transporter. American Journal of Physiology. Gastrointestinal and Liver Physiology. 283: G1398-411. PMID 12388212 DOI: 10.1152/ajpgi.00203.2002  1
2002 Zhou FC, Lesch KP, Murphy DL. Serotonin uptake into dopamine neurons via dopamine transporters: a compensatory alternative. Brain Research. 942: 109-19. PMID 12031859  0.4
2002 Holmes A, Murphy DL, Crawley JN. Reduced aggression in mice lacking the serotonin transporter. Psychopharmacology. 161: 160-7. PMID 11981596 DOI: 10.1007/s00213-002-1024-3  0.4
2001 Meiri G, Ben-Zion IZ, Greenberg BD, Murphy DL, Benjamin J. Influence of the serotonin antagonist, metergoline, on the anxiogenic effects of carbon dioxide, and on heart rate and neuroendocrine measures, in healthy volunteers. Human Psychopharmacology. 16: 237-245. PMID 12404576 DOI: 10.1002/hup.259  1
2001 Murphy DL, Li Q, Engel S, Wichems C, Andrews A, Lesch KP, Uhl G. Genetic perspectives on the serotonin transporter. Brain Research Bulletin. 56: 487-94. PMID 11750794 DOI: 10.1016/S0361-9230(01)00622-0  1
2001 Wassermann EM, Greenberg BD, Nguyen MB, Murphy DL. Motor cortex excitability correlates with an anxiety-related personality trait. Biological Psychiatry. 50: 377-82. PMID 11543742 DOI: 10.1016/S0006-3223(01)01210-0  1
2001 Persico AM, Mengual E, Moessner R, Hall FS, Revay RS, Sora I, Arellano J, DeFelipe J, Gimenez-Amaya JM, Conciatori M, Marino R, Baldi A, Cabib S, Pascucci T, Uhl GR, ... Murphy DL, et al. Barrel pattern formation requires serotonin uptake by thalamocortical afferents, and not vesicular monoamine release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6862-73. PMID 11517274  1
2001 Chen JJ, Li Z, Pan H, Murphy DL, Tamir H, Koepsell H, Gershon MD. Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6348-61. PMID 11487658  1
2001 Sora I, Hall FS, Andrews AM, Itokawa M, Li XF, Wei HB, Wichems C, Lesch KP, Murphy DL, Uhl GR. Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. Proceedings of the National Academy of Sciences of the United States of America. 98: 5300-5. PMID 11320258 DOI: 10.1073/pnas.091039298  1
2001 Ravary A, Muzerelle A, Darmon M, Murphy DL, Moessner R, Lesch KP, Gaspar P. Abnormal trafficking and subcellular localization of an N-terminally truncated serotonin transporter protein. The European Journal of Neuroscience. 13: 1349-62. PMID 11298795 DOI: 10.1046/j.0953-816X.2001.1511.x  1
2001 Enoch MA, Greenberg BD, Murphy DL, Goldman D. Sexually dimorphic relationship of a 5-HT2A promoter polymorphism with obsessive-compulsive disorder. Biological Psychiatry. 49: 385-8. PMID 11239910 DOI: 10.1016/S0006-3223(00)01040-4  1
2001 Gobbi G, Murphy DL, Lesch K, Blier P. Modifications of the serotonergic system in mice lacking serotonin transporters: an in vivo electrophysiological study. The Journal of Pharmacology and Experimental Therapeutics. 296: 987-95. PMID 11181933  1
2001 Daly RC, Su TP, Schmidt PJ, Pickar D, Murphy DL, Rubinow DR. Cerebrospinal fluid and behavioral changes after methyltestosterone administration: preliminary findings. Archives of General Psychiatry. 58: 172-7. PMID 11177119  1
2001 Salichon N, Gaspar P, Upton AL, Picaud S, Hanoun N, Hamon M, De Maeyer E, Murphy DL, Mossner R, Lesch KP, Hen R, Seif I. Excessive activation of serotonin (5-HT) 1B receptors disrupts the formation of sensory maps in monoamine oxidase a and 5-ht transporter knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 884-96. PMID 11157075  1
2000 Sher L, Greenberg BD, Murphy DL, Rosenthal NE, Sirota LA, Hamer DH. Pleiotropy of the serotonin transporter gene for seasonality and neuroticism. Psychiatric Genetics. 10: 125-30. PMID 11204348  1
2000 Li Q, Wichems C, Heils A, Lesch KP, Murphy DL. Reduction in the density and expression, but not G-protein coupling, of serotonin receptors (5-HT1A) in 5-HT transporter knock-out mice: gender and brain region differences. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7888-95. PMID 11050108  0.4
2000 Greenberg BD, Murphy DL, Rasmussen SA. Neuroanatomically based approaches to obsessive-compulsive disorder. Neurosurgery and transcranial magnetic stimulation. The Psychiatric Clinics of North America. 23: 671-86, xii. PMID 10986735  1
2000 Fabre V, Beaufour C, Evrard A, Rioux A, Hanoun N, Lesch KP, Murphy DL, Lanfumey L, Hamon M, Martres MP. Altered expression and functions of serotonin 5-HT1A and 5-HT1B receptors in knock-out mice lacking the 5-HT transporter. The European Journal of Neuroscience. 12: 2299-310. PMID 10947809 DOI: 10.1046/j.1460-9568.2000.00126.x  1
2000 Schmidt NB, Storey J, Greenberg BD, Santiago HT, Li Q, Murphy DL. Evaluating gene x psychological risk factor effects in the pathogenesis of anxiety: a new model approach. Journal of Abnormal Psychology. 109: 308-20. PMID 10895569 DOI: 10.1037//0021-843X.109.2.308  1
2000 Greenberg BD, Li Q, Lucas FR, Hu S, Sirota LA, Benjamin J, Lesch KP, Hamer D, Murphy DL. Association between the serotonin transporter promoter polymorphism and personality traits in a primarily female population sample. American Journal of Medical Genetics. 96: 202-16. PMID 10893498 DOI: 10.1002/(SICI)1096-8628(20000403)96:2<202::AID-AJMG16>3.0.CO;2-J  1
2000 Hu S, Brody CL, Fisher C, Gunzerath L, Nelson ML, Sabol SZ, Sirota LA, Marcus SE, Greenberg BD, Murphy DL, Hamer DH. Interaction between the serotonin transporter gene and neuroticism in cigarette smoking behavior. Molecular Psychiatry. 5: 181-8. PMID 10822346  1
2000 Greenberg BD, Ziemann U, Corá-Locatelli G, Harmon A, Murphy DL, Keel JC, Wassermann EM. Altered cortical excitability in obsessive-compulsive disorder. Neurology. 54: 142-7. PMID 10636140  1
1999 Hamer DH, Greenberg BD, Sabol SZ, Murphy DL. Role of the serotonin transporter gene in temperament and character. Journal of Personality Disorders. 13: 312-27. PMID 10633313  1
1999 Li Q, Wichems C, Heils A, Van De Kar LD, Lesch KP, Murphy DL. Reduction of 5-hydroxytryptamine (5-HT)(1A)-mediated temperature and neuroendocrine responses and 5-HT(1A) binding sites in 5-HT transporter knockout mice. The Journal of Pharmacology and Experimental Therapeutics. 291: 999-1007. PMID 10565817  0.4
1999 Sher L, Hardin TA, Greenberg BD, Murphy DL, Li Q, Rosenthal NE. Seasonality associated with the serotonin transporter promoter repeat length polymorphism. The American Journal of Psychiatry. 156: 1837. PMID 10553760  1
1999 Bengel D, Greenberg BD, Corá-Locatelli G, Altemus M, Heils A, Li Q, Murphy DL. Association of the serotonin transporter promoter regulatory region polymorphism and obsessive-compulsive disorder. Molecular Psychiatry. 4: 463-6. PMID 10523819  1
1999 Ben-Zion IZ, Meiri G, Greenberg BD, Murphy DL, Benjamin J. Enhancement of CO2-induced anxiety in healthy volunteers with the serotonin antagonist metergoline. The American Journal of Psychiatry. 156: 1635-7. PMID 10518177  1
1999 Altemus M, Greenberg BD, Keuler D, Jacobson KR, Murphy DL. Open trial of flutamide for treatment of obsessive-compulsive disorder. The Journal of Clinical Psychiatry. 60: 442-5. PMID 10453797  1
1999 Tariot PN, Upadhyaya A, Sunderland T, Cox C, Cohen RM, Murphy DL, Loy R. Physiologic and neuroendocrine responses to intravenous naloxone in subjects with Alzheimer's disease and age-matched controls. Biological Psychiatry. 46: 412-9. PMID 10435208 DOI: 10.1016/S0006-3223(98)00329-1  1
1999 Sirota LA, Greenberg BD, Murphy DL, Hamer DH. Non-linear association between the serotonin transporter promoter polymorphism and neuroticism: a caution against using extreme samples to identify quantitative trait loci. Psychiatric Genetics. 9: 35-8. PMID 10335550  1
1999 Benjamin J, Geraci M, McCann U, Greenberg BD, Murphy DL. Attenuated response to m-CPP and to pentagastrin after repeated m-CPP in panic disorder. Psychopharmacology. 143: 215-6. PMID 10326785 DOI: 10.1007/s002130050938  1
1999 Rioux A, Fabre V, Lesch KP, Moessner R, Murphy DL, Lanfumey L, Hamon M, Martres MP. Adaptive changes of serotonin 5-HT2A receptors in mice lacking the serotonin transporter. Neuroscience Letters. 262: 113-6. PMID 10203244 DOI: 10.1016/S0304-3940(99)00049-X  1
1999 Altemus M, Jacobson KR, Debellis M, Kling M, Pigott T, Murphy DL, Gold PW. Normal CSF oxytocin and NPY levels in OCD. Biological Psychiatry. 45: 931-3. PMID 10202583 DOI: 10.1016/S0006-3223(98)00263-7  1
1999 Greenberg BD, Tolliver TJ, Huang SJ, Li Q, Bengel D, Murphy DL. Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets. American Journal of Medical Genetics. 88: 83-7. PMID 10050973 DOI: 10.1002/(SICI)1096-8628(19990205)88:1<83::AID-AJMG15>3.0.CO;2-0  1
1999 Schuback DE, Mulligan EL, Sims KB, Tivol EA, Greenberg BD, Chang SF, Yang SL, Mau YC, Shen CY, Ho MS, Yang NH, Butler MG, Fink S, Schwartz CE, Berlin F, ... ... Murphy DL, et al. Screen for MAOA mutations in target human groups. American Journal of Medical Genetics. 88: 25-8. PMID 10050962 DOI: 10.1002/(SICI)1096-8628(19990205)88:1<25::AID-AJMG4>3.0.CO;2-E  1
1999 Sabol SZ, Nelson ML, Fisher C, Gunzerath L, Brody CL, Hu S, Sirota LA, Marcus SE, Greenberg BD, Lucas FR, Benjamin J, Murphy DL, Hamer DH. A genetic association for cigarette smoking behavior. Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association. 18: 7-13. PMID 9925040 DOI: 10.1037/0278-6133.18.1.7  1
1998 Greenberg BD, Benjamin J, Martin JD, Keuler D, Huang SJ, Altemus M, Murphy DL. Delayed obsessive-compulsive disorder symptom exacerbation after a single dose of a serotonin antagonist in fluoxetine-treated but not untreated patients. Psychopharmacology. 140: 434-44. PMID 9888619 DOI: 10.1007/s002130050787  1
1998 Bengel D, Isaacs KR, Heils A, Lesch KP, Murphy DL. The appetite suppressant d-fenfluramine induces apoptosis in human serotonergic cells. Neuroreport. 9: 2989-93. PMID 9804303  0.4
1998 Murphy DL, Andrews AM, Wichems CH, Li Q, Tohda M, Greenberg B. Brain serotonin neurotransmission: an overview and update with an emphasis on serotonin subsystem heterogeneity, multiple receptors, interactions with other neurotransmitter systems, and consequent implications for understanding the actions of serotonergic drugs. The Journal of Clinical Psychiatry. 59: 4-12. PMID 9786305  1
1998 Corá-Locatelli G, Greenberg BD, Martin J, Murphy DL. Gabapentin augmentation for fluoxetine-treated patients with obsessive-compulsive disorder. The Journal of Clinical Psychiatry. 59: 480-1. PMID 9771822  1
1998 Greenberg BD, Murphy DL, Swedo SE. Symptom exacerbation of vocal tics and other symptoms associated with streptococcal pharyngitis in a patient with obsessive-compulsive disorder and tics. The American Journal of Psychiatry. 155: 1459-60. PMID 9766784  1
1998 Greenberg BD, Ziemann U, Harmon A, Murphy DL, Wassermann EM. Decreased neuronal inhibition in cerebral cortex in obsessive-compulsive disorder on transcranial magnetic stimulation. Lancet. 352: 881-2. PMID 9742988 DOI: 10.1016/S0140-6736(05)60009-8  1
1998 Broocks A, Pigott TA, Hill JL, Canter S, Grady TA, L'Heureux F, Murphy DL. Acute intravenous administration of ondansetron and m-CPP, alone and in combination, in patients with obsessive-compulsive disorder (OCD): behavioral and biological results. Psychiatry Research. 79: 11-20. PMID 9676822 DOI: 10.1016/S0165-1781(98)00029-8  1
1998 Greenberg BD, McMahon FJ, Murphy DL. Serotonin transporter candidate gene studies in affective disorders and personality: promises and potential pitfalls. Molecular Psychiatry. 3: 186-9. PMID 9672885  1
1998 Sora I, Wichems C, Takahashi N, Li XF, Zeng Z, Revay R, Lesch KP, Murphy DL, Uhl GR. Cocaine reward models: conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 95: 7699-704. PMID 9636213  0.4
1998 Enoch MA, Kaye WH, Rotondo A, Greenberg BD, Murphy DL, Goldman D. 5-HT2A promoter polymorphism -1438G/A, anorexia nervosa, and obsessive-compulsive disorder. Lancet. 351: 1785-6. PMID 9635956 DOI: 10.1016/S0140-6736(05)78746-8  1
1998 Murphy DL, Sims K, Eisenhofer G, Greenberg BD, George T, Berlin F, Zametkin A, Ernst M, Breakefield XO. Are MAO-A deficiency states in the general population and in putative high-risk populations highly uncommon? Journal of Neural Transmission. Supplementum. 52: 29-38. PMID 9564605  1
1998 Bengel D, Murphy DL, Andrews AM, Wichems CH, Feltner D, Heils A, Mössner R, Westphal H, Lesch KP. Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4-methylenedioxymethamphetamine ("Ecstasy") in serotonin transporter-deficient mice. Molecular Pharmacology. 53: 649-55. PMID 9547354  1
1998 Corá-Locatelli G, Greenberg BD, Martin JD, Murphy DL. Rebound psychiatric and physical symptoms after gabapentin discontinuation. The Journal of Clinical Psychiatry. 59: 131. PMID 9541157  1
1998 Broocks A, Little JT, Martin A, Minichiello MD, Dubbert B, Mack C, Tune L, Murphy DL, Sunderland T. The influence of ondansetron and m-chlorophenylpiperazine on scopolamine-induced cognitive, behavioral, and physiological responses in young healthy controls. Biological Psychiatry. 43: 408-16. PMID 9532345 DOI: 10.1016/S0006-3223(97)00388-0  1
1998 Corá-Locatelli G, Greenberg BD, Martin JD, Murphy DL. Valproate monotherapy in an SRI-intolerant OCD patient. The Journal of Clinical Psychiatry. 59: 82. PMID 9501891  1
1998 Heils A, Wichems C, Mössner R, Petri S, Glatz K, Bengel D, Murphy DL, Lesch KP. Functional characterization of the murine serotonin transporter gene promoter in serotonergic raphe neurons. Journal of Neurochemistry. 70: 932-9. PMID 9489712  0.4
1997 Bengel D, Jöhren O, Andrews AM, Heils A, Mössner R, Sanvitto GL, Saavedra JM, Lesch KP, Murphy DL. Cellular localization and expression of the serotonin transporter in mouse brain. Brain Research. 778: 338-45. PMID 9459551 DOI: 10.1016/S0006-8993(97)01080-9  1
1997 Greenberg BD, George MS, Martin JD, Benjamin J, Schlaepfer TE, Altemus M, Wassermann EM, Post RM, Murphy DL. Effect of prefrontal repetitive transcranial magnetic stimulation in obsessive-compulsive disorder: a preliminary study. The American Journal of Psychiatry. 154: 867-9. PMID 9167520  1
1997 Karayiorgou M, Altemus M, Galke BL, Goldman D, Murphy DL, Ott J, Gogos JA. Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder. Proceedings of the National Academy of Sciences of the United States of America. 94: 4572-5. PMID 9114031 DOI: 10.1073/pnas.94.9.4572  1
1997 Su TP, Schmidt PJ, Danaceau MA, Tobin MB, Rosenstein DL, Murphy DL, Rubinow DR. Fluoxetine in the treatment of premenstrual dysphoria. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 16: 346-56. PMID 9109106 DOI: 10.1016/S0893-133X(96)00245-X  1
1997 Schwartz PJ, Murphy DL, Wehr TA, Garcia-Borreguero D, Oren DA, Moul DE, Ozaki N, Snelbaker AJ, Rosenthal NE. Effects of meta-chlorophenylpiperazine infusions in patients with seasonal affective disorder and healthy control subjects. Diurnal responses and nocturnal regulatory mechanisms. Archives of General Psychiatry. 54: 375-85. PMID 9107154  1
1997 Mazzola-Pomietto P, Aulakh CS, Tolliver T, Murphy DL. Functional subsensitivity of 5-HT2A and 5-HT2C receptors mediating hyperthermia following acute and chronic treatment with 5-HT2A/2C receptor antagonists. Psychopharmacology. 130: 144-51. PMID 9106912  0.36
1997 Broocks A, Briggs NC, Pigott TA, Hill JL, Canter SK, Tolliver TJ, Baldemore D, Murphy DL. Behavioral, physiological and neuroendocrine responses in healthy volunteers to m-chlorophenylpiperazine (m-CPP) with and without ondansetron pretreatment. Psychopharmacology. 130: 91-103. PMID 9106905 DOI: 10.1007/s002130050215  1
1997 Su TP, Schmidt PJ, Danaceau M, Murphy DL, Rubinow DR. Effect of menstrual cycle phase on neuroendocrine and behavioral responses to the serotonin agonist m-chlorophenylpiperazine in women with premenstrual syndrome and controls. The Journal of Clinical Endocrinology and Metabolism. 82: 1220-8. PMID 9100599 DOI: 10.1210/jcem.82.4.3905  1
1997 Bengel D, Heils A, Petri S, Seemann M, Glatz K, Andrews A, Murphy DL, Lesch KP. Gene structure and 5'-flanking regulatory region of the murine serotonin transporter. Brain Research. Molecular Brain Research. 44: 286-92. PMID 9073170 DOI: 10.1016/S0169-328X(96)00234-3  1
1997 George DT, Benkelfat C, Rawlings RR, Eckardt MJ, Phillips MJ, Nutt DJ, Wynne D, Murphy DL, Linnoila M. Behavioral and neuroendocrine responses to m-chlorophenylpiperazine in subtypes of alcoholics and in healthy comparison subjects. The American Journal of Psychiatry. 154: 81-7. PMID 8988963  1
1997 Vitiello B, Martin A, Hill J, Mack C, Molchan S, Martinez R, Murphy DL, Sunderland T. Cognitive and behavioral effects of cholinergic, dopaminergic, and serotonergic blockade in humans. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 16: 15-24. PMID 8981385 DOI: 10.1016/S0893-133X(96)00134-0  1
1996 Andrews AM, Ladenheim B, Epstein CJ, Cadet JL, Murphy DL. Transgenic mice with high levels of superoxide dismutase activity are protected from the neurotoxic effects of 2'-NH2-MPTP on serotonergic and noradrenergic nerve terminals. Molecular Pharmacology. 50: 1511-9. PMID 8967972  1
1993 Andrews AM, Murphy DL. 2'-NH2-MPTP in Swiss Webster mice: evidence for long-term (6-month) depletions in cortical and hippocampal serotonin and norepinephrine, differential protection by selective uptake inhibitors or clorgyline and functional changes in central serotonin neurotransmission. The Journal of Pharmacology and Experimental Therapeutics. 267: 1432-9. PMID 8263805  1
1993 Andrews AM, Murphy DL. Fluoxetine and desipramine selectively attenuate 2'-NH2-MPTP-induced depletions in serotonin and norepinephrine. European Journal of Pharmacology. 250: 215-21. PMID 8112382 DOI: 10.1016/0014-2999(93)90384-T  1
1993 Andrews AM, Murphy DL. Sustained depletion of cortical and hippocampal serotonin and norepinephrine but not striatal dopamine by 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine (2'-NH2-MPTP): a comparative study with 2'-CH3-MPTP and MPTP. Journal of Neurochemistry. 60: 1167-70. PMID 8094744  1
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