| Year |
Citation |
Score |
| 2024 |
Tasca CI, Zuccarini M, Di Iorio P, Ciruela F. Lessons from the physiological role of guanosine in neurodegeneration and cancer: Toward a multimodal mechanism of action? Purinergic Signalling. PMID 39004650 DOI: 10.1007/s11302-024-10033-y |
0.337 |
|
| 2023 |
Sánchez-Fernández N, Gómez-Acero L, Sarasola LI, Argerich J, Chevigné A, Jacobson KA, Ciruela F, Fernández-Dueñas V, Aso E. Cannabidiol negatively modulates adenosine A receptor functioning in living cells. Acta Neuropsychiatrica. 1-14. PMID 37605951 DOI: 10.1017/neu.2023.30 |
0.537 |
|
| 2023 |
Skopál A, Ujlaki G, Gerencsér AT, Bankó C, Bacsó Z, Ciruela F, Virág L, Haskó G, Kókai E. Adenosine A Receptor Activation Regulates Niemann-Pick C1 Expression and Localization in Macrophages. Current Issues in Molecular Biology. 45: 4948-4969. PMID 37367064 DOI: 10.3390/cimb45060315 |
0.301 |
|
| 2023 |
Ferré S, Köfalvi A, Ciruela F, Justinova Z, Pistis M. Targeting corticostriatal transmission for the treatment of cannabinoid use disorder. Trends in Pharmacological Sciences. PMID 37331914 DOI: 10.1016/j.tips.2023.05.003 |
0.368 |
|
| 2023 |
Taura J, López-Cano M, Fernández-Dueñas V, Ciruela F. Visualizing G Protein-Coupled Receptor-Receptor Interactions in Brain Using Proximity Ligation In Situ Assay. Current Protocols. 3: e794. PMID 37289022 DOI: 10.1002/cpz1.794 |
0.826 |
|
| 2023 |
Morató X, Fernández-Dueñas V, Pérez-Villamor P, Valle-León M, Vela JM, Merlos M, Burgueño J, Ciruela F. Development of a Novel σ Receptor Biosensor Based on Its Heterodimerization with Binding Immunoglobulin Protein in Living Cells. Acs Chemical Neuroscience. PMID 37191585 DOI: 10.1021/acschemneuro.3c00206 |
0.825 |
|
| 2023 |
Godoy-Marín H, Jiménez-Sábado V, Tarifa C, Ginel A, Santos JLD, Bentzen BH, Hove-Madsen L, Ciruela F. Increased Density of Endogenous Adenosine A Receptors in Atrial Fibrillation: From Cellular and Porcine Models to Human Patients. International Journal of Molecular Sciences. 24. PMID 36835078 DOI: 10.3390/ijms24043668 |
0.793 |
|
| 2023 |
Burström V, Ågren R, Betari N, Valle-León M, Garro-Martínez E, Ciruela F, Sahlholm K. Dopamine-induced arrestin recruitment and desensitization of the dopamine D4 receptor is regulated by G protein-coupled receptor kinase-2. Frontiers in Pharmacology. 14: 1087171. PMID 36778010 DOI: 10.3389/fphar.2023.1087171 |
0.849 |
|
| 2023 |
Valle-León M, Casajuana-Martin N, Del Torrent CL, Argerich J, Gómez-Acero L, Sahlholm K, Ferré S, Pardo L, Ciruela F. Unique effect of clozapine on adenosine A-dopamine D receptor heteromerization. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 160: 114327. PMID 36736280 DOI: 10.1016/j.biopha.2023.114327 |
0.821 |
|
| 2022 |
Tarifa C, Vallmitjana A, Jiménez-Sábado V, Marchena M, Llach A, Herraiz-Martínez A, Godoy-Marín H, Nolla-Colomer C, Ginel A, Viñolas X, Montiel J, Ciruela F, Echebarria B, Benítez R, Cinca J, et al. Spatial Distribution of Calcium Sparks Determines Their Ability to Induce Afterdepolarizations in Human Atrial Myocytes. Jacc. Basic to Translational Science. 8: 1-15. PMID 36777175 DOI: 10.1016/j.jacbts.2022.07.013 |
0.773 |
|
| 2022 |
Prieto-Díaz R, González-Gómez M, Fojo-Carballo H, Azuaje J, El Maatougui A, Majellaro M, Loza MI, Brea J, Fernández-Dueñas V, Paleo MR, Díaz-Holguín A, Garcia-Pinel B, Mallo-Abreu A, Estévez JC, Andújar-Arias A, ... ... Ciruela F, et al. Exploring the Effect of Halogenation in a Series of Potent and Selective A Adenosine Receptor Antagonists. Journal of Medicinal Chemistry. PMID 36517209 DOI: 10.1021/acs.jmedchem.2c01768 |
0.692 |
|
| 2022 |
Crans RAJ, Wouters E, Valle-León M, Taura J, Massari CM, Fernández-Dueñas V, Stove CP, Ciruela F. Corrigendum: Striatal dopamine D2-muscarinic acetylcholine M1 receptor-receptor interaction in a model of movement disorders. Frontiers in Pharmacology. 13: 1075433. PMID 36467044 DOI: 10.3389/fphar.2022.1075433 |
0.824 |
|
| 2022 |
Ferré S, Sarasola LI, Quiroz C, Ciruela F. Presynaptic adenosine receptor heteromers as key modulators of glutamatergic and dopaminergic neurotransmission in the striatum. Neuropharmacology. 223: 109329. PMID 36375695 DOI: 10.1016/j.neuropharm.2022.109329 |
0.418 |
|
| 2022 |
Sarasola LI, Del Torrent CL, Pérez-Arévalo A, Argerich J, Casajuana-Martín N, Chevigné A, Fernández-Dueñas V, Ferré S, Pardo L, Ciruela F. The ADORA1 mutation linked to early-onset Parkinson's disease alters adenosine A-A receptor heteromer formation and function. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 156: 113896. PMID 36279718 DOI: 10.1016/j.biopha.2022.113896 |
0.692 |
|
| 2022 |
Ferré S, Belcher AM, Bonaventura J, Quiroz C, Sánchez-Soto M, Casadó-Anguera V, Cai NS, Moreno E, Boateng CA, Keck TM, Florán B, Earley CJ, Ciruela F, Casadó V, Rubinstein M, et al. Functional and pharmacological role of the dopamine D receptor and its polymorphic variants. Frontiers in Endocrinology. 13: 1014678. PMID 36267569 DOI: 10.3389/fendo.2022.1014678 |
0.356 |
|
| 2022 |
Garozzo R, Zuccarini M, Giuliani P, Di Liberto V, Mudò G, Caciagli F, Ciccarelli R, Ciruela F, Di Iorio P, Condorelli DF. Guanine inhibits the growth of human glioma and melanoma cell lines by interacting with GPR23. Frontiers in Pharmacology. 13: 970891. PMID 36199684 DOI: 10.3389/fphar.2022.970891 |
0.308 |
|
| 2022 |
Romero-Fernandez W, Taura JJ, Crans RAJ, Lopez-Cano M, Fores-Pons R, Narváez M, Carlsson J, Ciruela F, Fuxe K, Borroto-Escuela DO. The mGlu Receptor Protomer-Mediated Dopamine D Receptor Trans-Inhibition Is Dependent on the Adenosine A Receptor Protomer: Implications for Parkinson's Disease. Molecular Neurobiology. PMID 35829830 DOI: 10.1007/s12035-022-02946-9 |
0.848 |
|
| 2022 |
Ciruela F, Jacobson KA. Optical Control of Adenosine A Receptor Signaling: Towards a Multimodal Phototherapy in Psoriasis? Frontiers in Immunology. 13: 904762. PMID 35572558 DOI: 10.3389/fimmu.2022.904762 |
0.457 |
|
| 2022 |
Skopál A, Kéki T, Tóth PÁ, Csóka B, Koscsó B, Német ZH, Antonioli L, Ivessa A, Ciruela F, Virág L, Haskó G, Kókai E. Cathepsin D interacts with adenosine A2A receptors in mouse macrophages to modulate cell surface localization and inflammatory signaling. The Journal of Biological Chemistry. 101888. PMID 35367412 DOI: 10.1016/j.jbc.2022.101888 |
0.302 |
|
| 2022 |
Rodrigues MS, Ferreira SG, Quiroz C, Earley CJ, García-Borreguero D, Cunha RA, Ciruela F, Köfalvi A, Ferré S. Brain Iron Deficiency Changes the Stoichiometry of Adenosine Receptor Subtypes in Cortico-Striatal Terminals: Implications for Restless Legs Syndrome. Molecules (Basel, Switzerland). 27. PMID 35268590 DOI: 10.3390/molecules27051489 |
0.341 |
|
| 2021 |
Fernández-Dueñas V, Bonaventura J, Aso E, Luján R, Ferré S, Ciruela F. Overcoming the challenges of detecting gpcr oligomerization in the brain. Current Neuropharmacology. PMID 34736381 DOI: 10.2174/1570159X19666211104145727 |
0.73 |
|
| 2021 |
Ferré S, Ciruela F, Dessauer CW, González-Maeso J, Hébert TE, Jockers R, Logothetis DE, Pardo L. G protein-coupled receptor-effector macromolecular membrane assemblies (GEMMAs). Pharmacology & Therapeutics. 107977. PMID 34480967 DOI: 10.1016/j.pharmthera.2021.107977 |
0.346 |
|
| 2021 |
Hüll K, Fernández-Dueñas V, Schönberger M, López-Cano M, Trauner D, Ciruela F. Optical Control of Adenosine-Mediated Pain Modulation. Bioconjugate Chemistry. PMID 34448572 DOI: 10.1021/acs.bioconjchem.1c00387 |
0.81 |
|
| 2021 |
López-Cano M, Font J, Aso E, Sahlholm K, Cabré G, Giraldo J, De Koninck Y, Hernando J, Llebaria A, Fernández-Dueñas V, Ciruela F. Remote local photoactivation of morphine produces analgesia without opioid-related adverse effects. British Journal of Pharmacology. PMID 34363210 DOI: 10.1111/bph.15645 |
0.767 |
|
| 2021 |
López-Cano M, Filgaira I, Nolen EG, Cabré G, Hernando J, Tosh DK, Jacobson KA, Soler C, Ciruela F. Optical control of adenosine A receptor function in psoriasis. Pharmacological Research. 105731. PMID 34157422 DOI: 10.1016/j.phrs.2021.105731 |
0.785 |
|
| 2021 |
Alonso-Gardón M, Elorza-Vidal X, Castellanos A, La Sala G, Armand-Ugon M, Gilbert A, Di Pietro C, Pla-Casillanis A, Ciruela F, Gasull X, Nunes V, Martínez A, Schulte U, Cohen-Salmon M, Marazziti D, et al. Identification of the GlialCAM interactome: The G protein-coupled receptors GPRC5B and GPR37L1 modulate Megalencephalic leukoencephalopathy proteins. Human Molecular Genetics. PMID 34100078 DOI: 10.1093/hmg/ddab155 |
0.318 |
|
| 2021 |
Mattila SO, Tuhkanen HE, Lackman JJ, Konzack A, Morató X, Argerich J, Saftig P, Ciruela F, Petäjä-Repo UE. GPR37 is processed in the N-terminal ectodomain by ADAM10 and furin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21654. PMID 34042202 DOI: 10.1096/fj.202002385RR |
0.784 |
|
| 2021 |
Godoy-Marín H, Duroux R, Jacobson KA, Soler C, Colino-Lage H, Jiménez-Sábado V, Montiel J, Hove-Madsen L, Ciruela F. Adenosine A Receptors Are Upregulated in Peripheral Blood Mononuclear Cells from Atrial Fibrillation Patients. International Journal of Molecular Sciences. 22. PMID 33801676 DOI: 10.3390/ijms22073467 |
0.802 |
|
| 2021 |
Herraiz-Martínez A, Tarifa C, Jiménez-Sábado V, Llach A, Godoy-Marín H, Colino H, Nolla-Colomer C, Casabella S, Izquierdo-Castro P, Benítez I, Benítez R, Roselló-Díez E, Rodríguez-Font E, Viñolas X, Ciruela F, et al. Influence of sex on intracellular calcium homeostasis in patients with atrial fibrillation. Cardiovascular Research. PMID 33788918 DOI: 10.1093/cvr/cvab127 |
0.757 |
|
| 2021 |
Morató X, Garcia-Esparcia P, Argerich J, Llorens F, Zerr I, Paslawski W, Borràs E, Sabidó E, Petäjä-Repo UE, Fernández-Dueñas V, Ferrer I, Svenningsson P, Ciruela F. Ecto-GPR37: a potential biomarker for Parkinson's disease. Translational Neurodegeneration. 10: 8. PMID 33637132 DOI: 10.1186/s40035-021-00232-7 |
0.792 |
|
| 2021 |
J Crans RA, Ciruela F. Dopaminergic-cholinergic imbalance in movement disorders: a role for the novel striatal dopamine D- muscarinic acetylcholine M receptor heteromer. Neural Regeneration Research. 16: 1406-1408. PMID 33318429 DOI: 10.4103/1673-5374.300988 |
0.306 |
|
| 2020 |
Betari N, Sahlholm K, Morató X, Godoy-Marín H, Jáuregui O, Teigen K, Ciruela F, Haavik J. Inhibition of Tryptophan Hydroxylases and Monoamine Oxidase-A by the Proton Pump Inhibitor, Omeprazole- and Investigations. Frontiers in Pharmacology. 11: 593416. PMID 33324221 DOI: 10.3389/fphar.2020.593416 |
0.758 |
|
| 2020 |
Frinchi M, Verdi V, Plescia F, Ciruela F, Grillo M, Garozzo R, Condorelli DF, Di Iorio P, Caciagli F, Ciccarelli R, Belluardo N, Di Liberto V, Mudò G. Guanosine-Mediated Anxiolytic-Like Effect: Interplay with Adenosine A and A Receptors. International Journal of Molecular Sciences. 21. PMID 33291390 DOI: 10.3390/ijms21239281 |
0.309 |
|
| 2020 |
Valle-León M, Callado LF, Aso E, Cajiao-Manrique MM, Sahlholm K, López-Cano M, Soler C, Altafaj X, Watanabe M, Ferré S, Fernández-Dueñas V, Menchón JM, Ciruela F. Decreased striatal adenosine A-dopamine D receptor heteromerization in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33010795 DOI: 10.1038/s41386-020-00872-9 |
0.807 |
|
| 2020 |
Ågren R, Zeberg H, Maciej Stępniewski T, Free RB, Reilly SW, Luedtke RR, Århem P, Ciruela F, Sibley DR, Mach RH, Selent J, Nilsson J, Sahlholm K. A ligand with two modes of interaction with the dopamine D2 receptor - An induced-fit mechanism of insurmountable antagonism. Acs Chemical Neuroscience. PMID 32865974 DOI: 10.1021/Acschemneuro.0C00477 |
0.791 |
|
| 2020 |
Celli R, Wall MJ, Santolini I, Vergassola M, Di Menna L, Mascio G, Cannella M, van Luijtelaar G, Pittaluga A, Ciruela F, Bruno V, Nicoletti F, Ngomba RT. Pharmacological activation of mGlu5 receptors with the positive allosteric modulator, VU0360172 modulates thalamic GABAergic transmission. Neuropharmacology. 108240. PMID 32768418 DOI: 10.1016/J.Neuropharm.2020.108240 |
0.384 |
|
| 2020 |
Massari CM, Constantino LC, Marques NF, Binder LB, Valle-León M, López-Cano M, Fernández-Dueñas V, Ciruela F, Tasca CI. Involvement of adenosine A1 and A2A receptors on guanosine-mediated anti-tremor effects in reserpinized mice. Purinergic Signalling. PMID 32725400 DOI: 10.1007/S11302-020-09716-Z |
0.434 |
|
| 2020 |
Crans RAJ, Wouters E, Valle-León M, Taura J, Massari CM, Fernández-Dueñas V, Stove CP, Ciruela F. Striatal Dopamine D-Muscarinic Acetylcholine M Receptor-Receptor Interaction in a Model of Movement Disorders. Frontiers in Pharmacology. 11: 194. PMID 32231561 DOI: 10.3389/Fphar.2020.00194 |
0.819 |
|
| 2020 |
Fernández-Dueñas V, Qian M, Argerich J, Amaral C, Risseeuw MDP, Van Calenbergh S, Ciruela F. Design, Synthesis and Characterization of a New Series of Fluorescent Metabotropic Glutamate Receptor Type 5 Negative Allosteric Modulators. Molecules (Basel, Switzerland). 25. PMID 32230915 DOI: 10.3390/Molecules25071532 |
0.715 |
|
| 2020 |
Ciruela F. Special Issue: G Protein-Coupled Adenosine Receptors: Molecular Aspects and Beyond. International Journal of Molecular Sciences. 21. PMID 32183407 DOI: 10.3390/Ijms21061997 |
0.416 |
|
| 2020 |
Köfalvi A, Moreno E, Cordomí A, Cai NS, Fernández-Dueñas V, Ferreira SG, Guixà-González R, Sánchez-Soto M, Yano H, Casadó-Anguera V, Cunha RA, Sebastião AM, Ciruela F, Pardo L, Casadó V, et al. Control of glutamate release by complexes of adenosine and cannabinoid receptors. Bmc Biology. 18: 9. PMID 31973708 DOI: 10.1186/S12915-020-0739-0 |
0.745 |
|
| 2020 |
Ferré S, Ciruela F, Casadó V, Pardo L. Oligomerization of G protein-coupled receptors: Still doubted? Progress in Molecular Biology and Translational Science. 169: 297-321. PMID 31952690 DOI: 10.1016/Bs.Pmbts.2019.11.006 |
0.43 |
|
| 2019 |
Crans RAJ, Daelemans S, Raedt R, Ciruela F, Stove CP. Kainic acid-induced status epilepticus decreases mGlu receptor and phase-specifically downregulates Homer1b/c expression. Brain Research. 146640. PMID 31891692 DOI: 10.1016/J.Brainres.2019.146640 |
0.804 |
|
| 2019 |
Lanznaster D, Massari CM, Marková V, Šimková T, Duroux R, Jacobson KA, Fernández-Dueñas V, Tasca CI, Ciruela F. Adenosine A-A Receptor-Receptor Interaction: Contribution to Guanosine-Mediated Effects. Cells. 8. PMID 31847113 DOI: 10.3390/Cells8121630 |
0.744 |
|
| 2019 |
Yarur HE, Vega-Quiroga I, González MP, Noches V, Thomases DR, Andrés ME, Ciruela F, Tseng KY, Gysling K. Inhibitory Control of Basolateral Amygdalar Transmission to the Prefrontal Cortex by Local Corticotrophin Type 2 Receptor. The International Journal of Neuropsychopharmacology. PMID 31800046 DOI: 10.1093/Ijnp/Pyz065 |
0.383 |
|
| 2019 |
Ferré S, Ciruela F. Functional and Neuroprotective Role of Striatal Adenosine A Receptor Heterotetramers. Journal of Caffeine and Adenosine Research. 9: 89-97. PMID 31559390 DOI: 10.1089/caff.2019.0008 |
0.42 |
|
| 2019 |
López-Cano M, Fernández-Dueñas V, Ciruela F. Proximity Ligation Assay Image Analysis Protocol: Addressing Receptor-Receptor Interactions. Methods in Molecular Biology (Clifton, N.J.). 2040: 41-50. PMID 31432474 DOI: 10.1007/978-1-4939-9686-5_3 |
0.793 |
|
| 2019 |
Fernández-Dueñas V, Gómez-Soler M, Valle-León M, Watanabe M, Ferrer I, Ciruela F. Revealing Adenosine A-Dopamine D Receptor Heteromers in Parkinson's Disease Post-Mortem Brain through a New AlphaScreen-Based Assay. International Journal of Molecular Sciences. 20. PMID 31340557 DOI: 10.3390/Ijms20143600 |
0.821 |
|
| 2019 |
Morato X, Cunha RA, Ciruela F. G protein-coupled receptor 37 (GPR37) emerges as an important modulator of adenosinergic transmission in the striatum. Neural Regeneration Research. 14: 1912-1914. PMID 31290447 DOI: 10.4103/1673-5374.259610 |
0.803 |
|
| 2019 |
Soto D, Olivella M, Grau C, Armstrong J, Alcon C, Gasull X, Santos-Gómez A, Locubiche S, de Salazar MG, García-Díaz R, Gratacòs-Batlle E, Ramos-Vicente D, Chu-Van E, Colsch B, Fernández-Dueñas V, ... Ciruela F, et al. l-Serine dietary supplementation is associated with clinical improvement of loss-of-function -related pediatric encephalopathy. Science Signaling. 12. PMID 31213567 DOI: 10.1126/Scisignal.Aaw0936 |
0.669 |
|
| 2019 |
López-Cano M, Font J, Llebaria A, Fernández-Dueñas V, Ciruela F. Optical Modulation of Metabotropic Glutamate Receptor Type 5 In Vivo Using a Photoactive Drug. Methods in Molecular Biology (Clifton, N.J.). 1947: 351-359. PMID 30969427 DOI: 10.1007/978-1-4939-9121-1_20 |
0.81 |
|
| 2019 |
Ciruela F, Jacobson KA. Editorial: Purinergic Pharmacology. Frontiers in Pharmacology. 10: 21. PMID 30728779 DOI: 10.3389/Fphar.2019.00021 |
0.483 |
|
| 2019 |
Zanatta AP, Gonçalves R, Zanatta L, de Oliveria GT, Moraes ALL, Zamoner A, Fernández-Dueñas V, Lanznaster D, Ciruela F, Tasca CI, Delalande C, Menegaz D, Silva FRMB. New ionic targets of 3,3',5'-triiodothyronine at the plasma membrane of rat Sertoli cells. Biochimica Et Biophysica Acta. Biomembranes. PMID 30639285 DOI: 10.1016/J.Bbamem.2019.01.002 |
0.632 |
|
| 2019 |
Aso E, Fernández-Dueñas V, López-Cano M, Taura J, Watanabe M, Ferrer I, Luján R, Ciruela F. Adenosine A-Cannabinoid CB Receptor Heteromers in the Hippocampus: Cannabidiol Blunts Δ-Tetrahydrocannabinol-Induced Cognitive Impairment. Molecular Neurobiology. PMID 30610611 DOI: 10.1007/S12035-018-1456-3 |
0.824 |
|
| 2018 |
Morató X, Gonçalves FQ, Lopes JP, Jauregui O, Soler C, Fernández-Dueñas V, Cunha RA, Ciruela F. Chronic adenosine A receptor blockade induces locomotor sensitization and potentiates striatal LTD in GPR37 deficient mice. Journal of Neurochemistry. PMID 30578680 DOI: 10.1111/Jnc.14653 |
0.807 |
|
| 2018 |
Sahlholm K, Valle-León M, Fernández-Dueñas V, Ciruela F. Dopamine receptor heteromers: biasing antipsychotics. Future Medicinal Chemistry. PMID 30518245 DOI: 10.4155/Fmc-2018-0335 |
0.832 |
|
| 2018 |
Tasca CI, Lanznaster D, Oliveira KA, Fernández-Dueñas V, Ciruela F. Neuromodulatory Effects of Guanine-Based Purines in Health and Disease. Frontiers in Cellular Neuroscience. 12: 376. PMID 30459558 DOI: 10.3389/Fncel.2018.00376 |
0.697 |
|
| 2018 |
Núñez F, Taura J, Camacho J, López-Cano M, Fernández-Dueñas V, Castro N, Castro J, Ciruela F. PBF509, an Adenosine A Receptor Antagonist With Efficacy in Rodent Models of Movement Disorders. Frontiers in Pharmacology. 9: 1200. PMID 30405415 DOI: 10.3389/Fphar.2018.01200 |
0.818 |
|
| 2018 |
Gómez-Soler M, Cordobilla B, Morató X, Fernández-Dueñas V, Domingo JC, Ciruela F. Triglyceride Form of Docosahexaenoic Acid Mediates Neuroprotection in Experimental Parkinsonism. Frontiers in Neuroscience. 12: 604. PMID 30233293 DOI: 10.3389/Fnins.2018.00604 |
0.785 |
|
| 2018 |
Gómez de Salazar M, Grau C, Ciruela F, Altafaj X. Phosphoproteomic Alterations of Ionotropic Glutamate Receptors in the Hippocampus of the Ts65Dn Mouse Model of Down Syndrome. Frontiers in Molecular Neuroscience. 11: 226. PMID 30140203 DOI: 10.3389/Fnmol.2018.00226 |
0.364 |
|
| 2018 |
Jung C, Fernández-Dueñas V, Plata C, Garcia-Elias A, Ciruela F, Fernández-Fernández JM, Valverde MA. Functional coupling of GABA receptors and the channel TRPV4 mediates rapid progesterone signaling in the oviduct. Science Signaling. 11. PMID 30108184 DOI: 10.1126/Scisignal.Aam6558 |
0.688 |
|
| 2018 |
Morató X, Luján R, Gonçalves N, Watanabe M, Altafaj X, Carvalho AL, Fernández-Dueñas V, Cunha RA, Ciruela F. Metabotropic glutamate type 5 receptor requires contactin-associated protein 1 to control memory formation. Human Molecular Genetics. PMID 30010864 DOI: 10.1093/Hmg/Ddy264 |
0.809 |
|
| 2018 |
Sahlholm K, Valle-Leon M, Taura J, Fernandez-Duenas V, Ciruela F. Effects of the Dopamine Stabilizer, Pridopidine, on Basal and Phencyclidine-Induced Locomotion: Role of Dopamine D2 and Sigma-1 Receptors. Cns & Neurological Disorders Drug Targets. PMID 29952269 DOI: 10.2174/1871527317666180627103337 |
0.828 |
|
| 2018 |
Taura J, Nolen EG, Cabré G, Hernando J, Squarcialupi L, López-Cano M, Jacobson KA, Fernández-Dueñas V, Ciruela F. Remote control of movement disorders using a photoactive adenosine A receptor antagonist. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29859955 DOI: 10.1016/J.Jconrel.2018.05.033 |
0.84 |
|
| 2018 |
Sahlholm K, Valle-León M, Fernández-Dueñas V, Ciruela F. Pridopidine Reverses Phencyclidine-Induced Memory Impairment. Frontiers in Pharmacology. 9: 338. PMID 29692729 DOI: 10.3389/Fphar.2018.00338 |
0.809 |
|
| 2018 |
Ferré S, Bonaventura J, Zhu W, Hatcher-Solis C, Taura J, Quiroz C, Cai NS, Moreno E, Casadó-Anguera V, Kravitz AV, Thompson KR, Tomasi DG, Navarro G, Cordomí A, Pardo L, ... Ciruela F, et al. Essential Control of the Function of the Striatopallidal Neuron by Pre-coupled Complexes of Adenosine A-Dopamine D Receptor Heterotetramers and Adenylyl Cyclase. Frontiers in Pharmacology. 9: 243. PMID 29686613 DOI: 10.3389/Fphar.2018.00243 |
0.821 |
|
| 2018 |
Fernandez-Duenas V, Ferré S, Ciruela F. Adenosine A-dopamine Dreceptor heteromers operate striatal function: impact on Parkinson's disease pharmacotherapeutics. Neural Regeneration Research. 13: 241-243. PMID 29557372 DOI: 10.4103/1673-5374.226388 |
0.664 |
|
| 2018 |
Font J, López-Cano M, Notartomaso S, Scarselli P, Di Prieto P, Bresolí-Obach R, Battaglia G, Malhaire F, Rovira X, Catena J, Giraldo J, Pin JP, Fernández-Dueñas V, Goudet C, Nonell S, ... ... Ciruela F, et al. Correction: Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator. Elife. 7. PMID 29313801 DOI: 10.7554/Elife.34752 |
0.804 |
|
| 2017 |
López-Cano M, Fernández-Dueñas V, Llebaria A, Ciruela F. Formalin Murine Model of Pain. Bio-Protocol. 7: e2628. PMID 34595296 DOI: 10.21769/BioProtoc.2628 |
0.763 |
|
| 2017 |
Duroux R, Ciancetta A, Mannes P, Yu J, Boyapati S, Gizewski E, Yous S, Ciruela F, Auchampach JA, Gao ZG, Jacobson KA. Bitopic fluorescent antagonists of the A2A adenosine receptor based on pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine functionalized congeners. Medchemcomm. 8: 1659-1667. PMID 29250307 DOI: 10.1039/C7Md00247E |
0.555 |
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| 2017 |
Fernández-Dueñas V, Pérez-Arévalo A, Altafaj X, Ferré S, Ciruela F. Adenosine A1-A2A Receptor Heteromer as a Possible Target for Early-Onset Parkinson's Disease. Frontiers in Neuroscience. 11: 652. PMID 29213228 DOI: 10.3389/Fnins.2017.00652 |
0.709 |
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| 2017 |
Luján R, Aguado C, Ciruela F, Cózar J, Kleindienst D, de la Ossa L, Bettler B, Wickman K, Watanabe M, Shigemoto R, Fukazawa Y. Differential association of GABAB receptors with their effector ion channels in Purkinje cells. Brain Structure & Function. PMID 29177691 DOI: 10.1007/S00429-017-1568-Y |
0.376 |
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| 2017 |
Taura J, Valle-León M, Sahlholm K, Watanabe M, Van Craenenbroeck K, Fernández-Dueñas V, Ferré S, Ciruela F. Behavioral control by striatal A2A -dopamine D2 receptor heteromers. Genes, Brain, and Behavior. PMID 29053217 DOI: 10.1111/Gbb.12432 |
0.699 |
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| 2017 |
Massari CM, López-Cano M, Núñez F, Fernández-Dueñas V, Tasca CI, Ciruela F. Antiparkinsonian Efficacy of Guanosine in Rodent Models of Movement Disorder. Frontiers in Pharmacology. 8: 700. PMID 29046640 DOI: 10.3389/Fphar.2017.00700 |
0.787 |
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| 2017 |
Moscoso-Castro M, López-Cano M, Gracia-Rubio I, Ciruela F, Valverde O. Cognitive impairments associated with alterations in synaptic proteins induced by the genetic loss of adenosine A2A receptors in mice. Neuropharmacology. PMID 28844595 DOI: 10.1016/J.Neuropharm.2017.08.027 |
0.763 |
|
| 2017 |
Morató X, Luján R, López-Cano M, Gandía J, Stagljar I, Watanabe M, Cunha RA, Fernández-Dueñas V, Ciruela F. The Parkinson's disease-associated GPR37 receptor interacts with striatal adenosine A2A receptor controlling its cell surface expression and function in vivo. Scientific Reports. 7: 9452. PMID 28842709 DOI: 10.1038/S41598-017-10147-X |
0.855 |
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| 2017 |
Sahlholm K, Gómez-Soler M, Valle-León M, López-Cano M, Taura JJ, Ciruela F, Fernández-Dueñas V. Antipsychotic-Like Efficacy of Dopamine D2 Receptor-Biased Ligands is Dependent on Adenosine A2A Receptor Expression. Molecular Neurobiology. PMID 28779351 DOI: 10.1007/S12035-017-0696-Y |
0.807 |
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| 2017 |
Soto D, Olivella M, Grau C, Armstrong J, Alcon C, Gasull X, Gómez de Salazar M, Gratacòs-Batlle E, Ramos-Vicente D, Fernández-Dueñas V, Ciruela F, Bayés À, Sindreu C, López-Sala A, García-Cazorla À, et al. Rett-like Severe Encephalopathy Caused by a De Novo GRIN2B Mutation Is Attenuated by D-serine Dietary Supplement. Biological Psychiatry. PMID 28734458 DOI: 10.1016/J.Biopsych.2017.05.028 |
0.651 |
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| 2017 |
Ciruela F, Sotelo E. Special Issue: Adenosine Receptors. Molecules (Basel, Switzerland). 22. PMID 28726742 DOI: 10.3390/Molecules22071220 |
0.437 |
|
| 2017 |
Morató X, López-Cano M, Canas PM, Cunha RA, Ciruela F. Brain Membrane Fractionation: An Ex Vivo Approach to Assess Subsynaptic Protein Localization. Journal of Visualized Experiments : Jove. PMID 28570537 DOI: 10.3791/55661 |
0.778 |
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| 2017 |
Oliveira PA, Dalton JAR, López-Cano M, Ricarte A, Morató X, Matheus FC, Cunha AS, Müller CE, Takahashi RN, Fernández-Dueñas V, Giraldo J, Prediger RD, Ciruela F. Angiotensin II type 1/adenosine A 2A receptor oligomers: a novel target for tardive dyskinesia. Scientific Reports. 7: 1857. PMID 28500295 DOI: 10.1038/S41598-017-02037-Z |
0.854 |
|
| 2017 |
Font J, López-Cano M, Notartomaso S, Scarselli P, Di Pietro P, Bresolí-Obach R, Battaglia G, Malhaire F, Rovira X, Catena J, Giraldo J, Pin JP, Fernández-Dueñas V, Goudet C, Nonell S, ... Ciruela F, et al. Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator. Elife. 6. PMID 28395733 DOI: 10.7554/Elife.23545 |
0.822 |
|
| 2017 |
Sokolina K, Kittanakom S, Snider J, Kotlyar M, Maurice P, Gandía J, Benleulmi-Chaachoua A, Tadagaki K, Oishi A, Wong V, Malty RH, Deineko V, Aoki H, Amin S, Yao Z, ... ... Ciruela F, et al. Systematic protein-protein interaction mapping for clinically relevant human GPCRs. Molecular Systems Biology. 13: 918. PMID 28298427 DOI: 10.15252/Msb.20167430 |
0.819 |
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| 2017 |
Fernández-Dueñas V, Azuaje J, Morató X, Cordobilla B, Domingo JC, Sotelo E, Ciruela F. Synthesis and Characterization of a New Bivalent Ligand Combining Caffeine and Docosahexaenoic Acid. Molecules (Basel, Switzerland). 22. PMID 28264466 DOI: 10.3390/Molecules22030366 |
0.811 |
|
| 2017 |
Gómez-Santacana X, Pittolo S, Rovira X, Lopez M, Zussy C, Dalton JA, Faucherre A, Jopling C, Pin JP, Ciruela F, Goudet C, Giraldo J, Gorostiza P, Llebaria A. Illuminating Phenylazopyridines To Photoswitch Metabotropic Glutamate Receptors: From the Flask to the Animals. Acs Central Science. 3: 81-91. PMID 28149957 DOI: 10.1021/Acscentsci.6B00353 |
0.448 |
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| 2017 |
Fernández-Dueñas V, Burgueño J, Ciruela F. Exploring Drug-Receptor Interaction Kinetics: Lessons from a Sigma-1 Receptor Transmembrane Biosensor. Frontiers in Pharmacology. 8: 4. PMID 28144220 DOI: 10.3389/Fphar.2017.00004 |
0.844 |
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| 2017 |
Piirainen H, Taura J, Kursula P, Ciruela F, Jaakola VP. Calcium modulates calmodulin/α-actinin 1 interaction with and agonist-dependent internalization of the adenosine A2A receptor. Biochimica Et Biophysica Acta. PMID 28130124 DOI: 10.1016/J.Bbamcr.2017.01.013 |
0.792 |
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| 2017 |
Moreno E, Chiarlone A, Medrano M, Puigdellívol M, Bibic L, Howell LA, Resel E, Puente N, Casarejos MJ, Perucho J, Botta J, Suelves N, Ciruela F, Ginés S, Galve-Roperh I, et al. Singular Location and Signaling Profile of Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Dorsal Striatum. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28102227 DOI: 10.1038/Npp.2017.12 |
0.724 |
|
| 2016 |
Rial D, Morató X, Real JI, Gonçalves FQ, Stagljar I, Pereira FC, Fernández-Dueñas V, Cunha RA, Ciruela F. Parkinson's disease-associated GPR37 receptor regulates cocaine-mediated synaptic depression in corticostriatal synapses. Neuroscience Letters. PMID 28007645 DOI: 10.1016/J.Neulet.2016.12.040 |
0.786 |
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| 2016 |
Gaitán-Peñas H, Gradogna A, Laparra-Cuervo L, Solsona C, Fernández-Dueñas V, Barrallo-Gimeno A, Ciruela F, Lakadamyali M, Pusch M, Estévez R. Investigation of LRRC8-Mediated Volume-Regulated Anion Currents in Xenopus Oocytes. Biophysical Journal. 111: 1429-1443. PMID 27705766 DOI: 10.1016/J.Bpj.2016.08.030 |
0.658 |
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| 2016 |
Di Liberto V, Mudò G, Garozzo R, Frinchi M, Fernandez-Dueñas V, Di Iorio P, Ciccarelli R, Caciagli F, Condorelli DF, Ciruela F, Belluardo N. The Guanine-Based Purinergic System: The Tale of An Orphan Neuromodulation. Frontiers in Pharmacology. 7: 158. PMID 27378923 DOI: 10.3389/Fphar.2016.00158 |
0.745 |
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| 2016 |
Manils J, Eduard C, Viña-Vilaseca A, López-Cano M, Díez-Villanueva A, Gómez D, Marruecos L, Ferran M, Benito C, Perrino FW, Vavouri T, Maria de Anta J, Ciruela F, Soler C. The exonuclease TREX2 shapes psoriatic phenotype. The Journal of Investigative Dermatology. PMID 27365293 DOI: 10.1016/J.Jid.2016.05.122 |
0.72 |
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| 2016 |
Moscoso-Castro M, Gracia-Rubio I, Ciruela F, Valverde O. Genetic blockade of adenosine A2A receptors induces cognitive impairments and anatomical changes related to psychotic symptoms in mice. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 27133030 DOI: 10.1016/J.Euroneuro.2016.04.003 |
0.345 |
|
| 2016 |
Rodrigues RJ, Almeida T, Díaz-Hernández M, Marques JM, Franco R, Solsona C, Miras-Portugal MT, Ciruela F, Cunha RA. Presynaptic P2X1-3 and α3-containing Nicotinic Receptors Assemble Into Functionally Interacting Ion Channels in the Rat Hippocampus. Neuropharmacology. PMID 26801076 DOI: 10.1016/J.Neuropharm.2016.01.022 |
0.407 |
|
| 2016 |
Guixà-González R, Javanainen M, Gómez-Soler M, Cordobilla B, Domingo JC, Sanz F, Pastor M, Ciruela F, Martinez-Seara H, Selent J. Membrane omega-3 fatty acids modulate the oligomerisation kinetics of adenosine A2A and dopamine D2 receptors. Scientific Reports. 6: 19839. PMID 26796668 DOI: 10.1038/Srep19839 |
0.849 |
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| 2016 |
Fernández-Dueñas V, Durroux T, Ciruela F. Fluorescent ligands and TR-FRET to study receptor–receptor interactions in the brain Neuromethods. 110: 99-107. DOI: 10.1007/978-1-4939-3064-7_8 |
0.302 |
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| 2016 |
Gómez-Soler M, Fernández-Dueñas V, Ciruela F. GPCR-mediated MAPK/ERK cascade activation in mouse striatal slices Neuromethods. 110: 465-472. DOI: 10.1007/978-1-4939-3064-7_29 |
0.322 |
|
| 2016 |
Taura J, Fernández-Dueñas V, Ciruela F. Determination of GPCR-mediated cAMP accumulation in rat striatal synaptosomes Neuromethods. 110: 455-463. DOI: 10.1007/978-1-4939-3064-7_28 |
0.401 |
|
| 2015 |
Soto-Cerrato V, Manuel-Manresa P, Hernando E, Calabuig-Fariñas S, Martinez-Romero A, Fernandez Dueñas V, Sahlholm K, Knopfel T, Garcia-Valverde M, Rodilla AM, Jantus-Lewintre E, Farras R, Ciruela F, Perez-Tomas R, Quesada R. Facilitated Anion Transport Induces Hyperpolarization of the Cell Membrane that Triggers Differentiation and Cell Death in Cancer Stem Cells. Journal of the American Chemical Society. PMID 26632983 DOI: 10.1021/Jacs.5B09970 |
0.631 |
|
| 2015 |
Taura J, Fernández-Dueñas V, Ciruela F. Visualizing G Protein-Coupled Receptor-Receptor Interactions in Brain Using Proximity Ligation In Situ Assay. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. 67: 17.17.1-17.17.16. PMID 26061241 DOI: 10.1002/0471143030.Cb1717S67 |
0.854 |
|
| 2015 |
Borroto-Escuela DO, Pérez-Alea M, Narvaez M, Tarakanov AO, Mudó G, Jiménez-Beristain A, Agnati LF, Ciruela F, Belluardo N, Fuxe K. Enhancement of the FGFR1 signaling in the FGFR1-5-HT1A heteroreceptor complex in midbrain raphe 5-HT neuron systems. Relevance for neuroplasticity and depression. Biochemical and Biophysical Research Communications. 463: 180-6. PMID 25957476 DOI: 10.1016/J.Bbrc.2015.04.133 |
0.35 |
|
| 2015 |
Ciruela F, Fernández-Dueñas V, Jacobson KA. Lighting up G protein-coupled purinergic receptors with engineered fluorescent ligands. Neuropharmacology. PMID 25890205 DOI: 10.1016/J.Neuropharm.2015.04.001 |
0.754 |
|
| 2015 |
Gandía J, Morató X, Stagljar I, Fernández-Dueñas V, Ciruela F. Adenosine A2A receptor-mediated control of pilocarpine-induced tremulous jaw movements is Parkinson's disease-associated GPR37 receptor-dependent. Behavioural Brain Research. 288: 103-6. PMID 25862943 DOI: 10.1016/J.Bbr.2015.04.001 |
0.848 |
|
| 2015 |
Lopes JP, Morató X, Souza C, Pinhal C, Machado NJ, Canas PM, Silva HB, Stagljar I, Gandía J, Fernández-Dueñas V, Luján R, Cunha RA, Ciruela F. The role of parkinson's disease-associated receptor GPR37 in the hippocampus: functional interplay with the adenosinergic system. Journal of Neurochemistry. 134: 135-46. PMID 25824528 DOI: 10.1111/Jnc.13109 |
0.818 |
|
| 2015 |
Ciruela F, Fernández-Dueñas V. GPCR oligomerization analysis by means of BRET and dFRAP. Methods in Molecular Biology (Clifton, N.J.). 1272: 133-41. PMID 25563182 DOI: 10.1007/978-1-4939-2336-6_10 |
0.68 |
|
| 2015 |
Constantino LC, Pamplona FA, Matheus FC, Ludka FK, Gomez-Soler M, Ciruela F, Boeck CR, Prediger RD, Tasca CI. Adenosine A1 receptor activation modulates N-methyl-d-aspartate (NMDA) preconditioning phenotype in the brain. Behavioural Brain Research. 282: 103-10. PMID 25557798 DOI: 10.1016/J.Bbr.2014.12.056 |
0.813 |
|
| 2015 |
Fernández-Dueñas V, Taura JJ, Cottet M, Gómez-Soler M, López-Cano M, Ledent C, Watanabe M, Trinquet E, Pin JP, Luján R, Durroux T, Ciruela F. Untangling dopamine-adenosine receptor-receptor assembly in experimental parkinsonism in rats. Disease Models & Mechanisms. 8: 57-63. PMID 25398851 DOI: 10.1242/Dmm.018143 |
0.804 |
|
| 2015 |
Ciruela F, Fernández-Dueñas V, Contreras F, Arnau JM, Menchón JM, Vallano A. Adenosine in the neurobiology of schizophrenia: Potential adenosine receptor-based pharmacotherapy Psychiatry and Neuroscience Update: Bridging the Divide. 375-388. DOI: 10.1007/978-3-319-17103-6_27 |
0.306 |
|
| 2015 |
Ciruela F, Constantino LC, Lanzaster D, Dal-Cim T, Tasca CI, Fernández-Dueñas V. Adenosine receptors, oligomerization and parkinson's disease pharmacotherapy Adenosine Signaling Mechanisms: Pharmacology, Functions and Therapeutic Aspects. 221-236. |
0.384 |
|
| 2014 |
GarcÃa-Negredo G, Soto D, Llorente J, Morató X, Galenkamp KM, Gómez-Soler M, Fernández-Dueñas V, Watanabe M, Adelman JP, Shigemoto R, Fukazawa Y, Luján R, Ciruela F. Coassembly and coupling of SK2 channels and mGlu5 receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14793-802. PMID 25355231 DOI: 10.1523/Jneurosci.2038-14.2014 |
0.453 |
|
| 2014 |
Fernández-Dueñas V, Gómez-Soler M, López-Cano M, Taura JJ, Ledent C, Watanabe M, Jacobson KA, Vilardaga JP, Ciruela F. Uncovering caffeine's adenosine A2A receptor inverse agonism in experimental parkinsonism. Acs Chemical Biology. 9: 2496-501. PMID 25268872 DOI: 10.1021/Cb5005383 |
0.822 |
|
| 2014 |
Bahamonde MI, Taura J, Paoletta S, Gakh AA, Chakraborty S, Hernando J, Fernández-Dueñas V, Jacobson KA, Gorostiza P, Ciruela F. Photomodulation of G protein-coupled adenosine receptors by a novel light-switchable ligand. Bioconjugate Chemistry. 25: 1847-54. PMID 25248077 DOI: 10.1021/Bc5003373 |
0.859 |
|
| 2014 |
Ciruela F, Vallano A, Cuffí ML, Carbonell L, Sánchez S, Arnau JM, Tasca C, Fernández-Dueñas V, Gómez-Soler M. Deciphering G protein-coupled receptor biology with fluorescence-based methods. Current Pharmaceutical Biotechnology. 15: 962-70. PMID 25213309 DOI: 10.2174/1389201015666140909125119 |
0.836 |
|
| 2014 |
Fuenzalida J, Galaz P, Araya KA, Slater PG, Blanco EH, Campusano JM, Ciruela F, Gysling K. Dopamine D1 and corticotrophin-releasing hormone type-2α receptors assemble into functionally interacting complexes in living cells. British Journal of Pharmacology. 171: 5650-64. PMID 25073922 DOI: 10.1111/Bph.12868 |
0.479 |
|
| 2014 |
Ciruela F, Jacobson KA, Fernández-Dueñas V. Portraying G protein-coupled receptors with fluorescent ligands. Acs Chemical Biology. 9: 1918-28. PMID 25010291 DOI: 10.1021/Cb5004042 |
0.748 |
|
| 2014 |
Villar-Menéndez I, Nuñez F, Díaz-Sánchez S, Albasanz JL, Taura J, Fernández-Dueñas V, Ferrer I, Martín M, Ciruela F, Barrachina M. Striatal adenosine A2A receptor expression is controlled by S-adenosyl-L-methionine-mediated methylation. Purinergic Signalling. 10: 523-8. PMID 24943396 DOI: 10.1007/S11302-014-9417-4 |
0.823 |
|
| 2014 |
Gómez-Soler M, Fernández-Dueñas V, Portillo-Salido E, Pérez P, Zamanillo D, Vela JM, Burgueño J, Ciruela F. Predicting the antinociceptive efficacy of σ(1) receptor ligands by a novel receptor fluorescence resonance energy transfer (FRET) based biosensor. Journal of Medicinal Chemistry. 57: 238-42. PMID 24354313 DOI: 10.1021/Jm401529T |
0.48 |
|
| 2014 |
Fuxe K, Borroto-Escuela DO, Romero-Fernandez W, Palkovits M, Tarakanov AO, Ciruela F, Agnati LF. Moonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 131-55. PMID 24105074 DOI: 10.1038/Npp.2013.242 |
0.536 |
|
| 2014 |
Fuxe K, Borroto-Escuela DO, Ciruela F, Guidolin D, Agnati LF. Receptor-receptor interactions in heteroreceptor complexes: a new principle in biology. Focus on their role in learning and memory Neuroscience Discovery. 2: 6. DOI: 10.7243/2052-6946-2-6 |
0.33 |
|
| 2014 |
Fernández-Dueñas V, Jacobson K, Ciruela F. Adenosine A2A Receptor Ligand Binding Experiments by Using Real-time Single-cell FRET Bio-Protocol. 4. DOI: 10.21769/bioprotoc.1070 |
0.484 |
|
| 2014 |
Jacobson K, Ciruela F. Synthesis of the Adenosine A2A Receptor Fluorescent Agonist MRS5424 Bio-Protocol. 4. DOI: 10.21769/BIOPROTOC.1069 |
0.526 |
|
| 2014 |
Guixà-González R, Javanainen M, Martinez-Seara H, Gómez-Soler M, Domingo JC, Vattulainen I, Ciruela F, Selent J. Cell Membrane Composition Affects GPCR Aggregation Biophysical Journal. 106: 5-7. DOI: 10.1016/J.Bpj.2013.11.2890 |
0.366 |
|
| 2013 |
Vallano A, Fernandez-Duenas V, Garcia-Negredo G, Quijada MA, Simon CP, Cuffà ML, Carbonell L, Sanchez S, Arnau JM, Ciruela F. Targeting striatal metabotropic glutamate receptor type 5 in Parkinson's disease: bridging molecular studies and clinical trials. Cns & Neurological Disorders Drug Targets. 12: 1128-42. PMID 24040811 DOI: 10.2174/18715273113129990115 |
0.499 |
|
| 2013 |
Ferrero JJ, Alvarez AM, RamÃrez-Franco J, Godino MC, Bartolomé-MartÃn D, Aguado C, Torres M, Luján R, Ciruela F, Sánchez-Prieto J. β-Adrenergic receptors activate exchange protein directly activated by cAMP (Epac), translocate Munc13-1, and enhance the Rab3A-RIM1α interaction to potentiate glutamate release at cerebrocortical nerve terminals. The Journal of Biological Chemistry. 288: 31370-85. PMID 24036110 DOI: 10.1074/Jbc.M113.463877 |
0.362 |
|
| 2013 |
Fernández-Dueñas V, Gómez-Soler M, Morató X, Núñez F, Das A, Kumar TS, Jaumà S, Jacobson KA, Ciruela F. Dopamine D(2) receptor-mediated modulation of adenosine A(2A) receptor agonist binding within the A(2A)R/D(2)R oligomer framework. Neurochemistry International. 63: 42-6. PMID 23619397 DOI: 10.1016/J.Neuint.2013.04.006 |
0.595 |
|
| 2013 |
Incontro S, Ciruela F, Ziff E, Hofmann F, Sánchez-Prieto J, Torres M. The type II cGMP dependent protein kinase regulates GluA1 levels at the plasma membrane of developing cerebellar granule cells. Biochimica Et Biophysica Acta. 1833: 1820-31. PMID 23545413 DOI: 10.1016/J.Bbamcr.2013.03.021 |
0.424 |
|
| 2013 |
Balana B, Bahima L, Bodhinathan K, Taura JJ, Taylor NM, Nettleton MY, Ciruela F, Slesinger PA. Ras-association domain of sorting Nexin 27 is critical for regulating expression of GIRK potassium channels. Plos One. 8: e59800. PMID 23536889 DOI: 10.1371/Journal.Pone.0059800 |
0.726 |
|
| 2013 |
Agnati LF, Guidolin D, Woods AS, Ciruela F, Carone C, Vallelunga A, Escuela DO, Genedani S, Fuxe K. A new interpretative paradigm for Conformational Protein Diseases. Current Protein & Peptide Science. 14: 141-60. PMID 23441893 DOI: 10.2174/1389203711314020006 |
0.306 |
|
| 2013 |
Gandía J, Fernández-Dueñas V, Morató X, Caltabiano G, González-Muñiz R, Pardo L, Stagljar I, Ciruela F. The Parkinson's disease-associated GPR37 receptor-mediated cytotoxicity is controlled by its intracellular cysteine-rich domain. Journal of Neurochemistry. 125: 362-72. PMID 23398388 DOI: 10.1111/Jnc.12196 |
0.841 |
|
| 2013 |
Borroto-Escuela DO, Romero-Fernandez W, Garriga P, Ciruela F, Narvaez M, Tarakanov AO, Palkovits M, Agnati LF, Fuxe K. G protein-coupled receptor heterodimerization in the brain. Methods in Enzymology. 521: 281-94. PMID 23351745 DOI: 10.1016/B978-0-12-391862-8.00015-6 |
0.47 |
|
| 2012 |
Fuxe K, Borroto-Escuela DO, Romero-Fernandez W, Tarakanov AO, Calvo F, Garriga P, Tena M, Narvaez M, Millón C, Parrado C, Ciruela F, Agnati LF, Narvaez JA, Díaz-Cabiale Z. On the existence and function of galanin receptor heteromers in the central nervous system. Frontiers in Endocrinology. 3: 127. PMID 23112793 DOI: 10.3389/Fendo.2012.00127 |
0.528 |
|
| 2012 |
Fernández-Dueñas V, Gómez-Soler M, Jacobson KA, Kumar ST, Fuxe K, Borroto-Escuela DO, Ciruela F. Molecular determinants of A2AR-D2R allosterism: role of the intracellular loop 3 of the D2R. Journal of Neurochemistry. 123: 373-84. PMID 22924752 DOI: 10.1111/J.1471-4159.2012.07956.X |
0.551 |
|
| 2012 |
Canela L, Selga E, GarcÃa-MartÃnez JM, Amaral OB, Fernández-Dueñas V, Alberch J, Canela EI, Franco R, Noé V, LluÃs C, Ciudad CJ, Ciruela F. Transcriptional profiling of striatal neurons in response to single or concurrent activation of dopamine D2, adenosine A(2A) and metabotropic glutamate type 5 receptors: focus on beta-synuclein expression. Gene. 508: 199-205. PMID 22892378 DOI: 10.1016/J.Gene.2012.07.074 |
0.838 |
|
| 2012 |
Fernández-Dueñas V, Llorente J, GandÃa J, Borroto-Escuela DO, Agnati LF, Tasca CI, Fuxe K, Ciruela F. Fluorescence resonance energy transfer-based technologies in the study of protein-protein interactions at the cell surface. Methods (San Diego, Calif.). 57: 467-72. PMID 22683304 DOI: 10.1016/J.Ymeth.2012.05.007 |
0.311 |
|
| 2012 |
Fuxe K, Borroto-Escuela DO, Romero-Fernandez W, Diaz-Cabiale Z, Rivera A, Ferraro L, Tanganelli S, Tarakanov AO, Garriga P, Narváez JA, Ciruela F, Guescini M, Agnati LF. Extrasynaptic neurotransmission in the modulation of brain function. Focus on the striatal neuronal-glial networks. Frontiers in Physiology. 3: 136. PMID 22675301 DOI: 10.3389/Fphys.2012.00136 |
0.424 |
|
| 2012 |
Ciruela F, Fernández-Dueñas V, Llorente J, Borroto-Escuela D, Cuffà ML, Carbonell L, Sánchez S, Agnati LF, Fuxe K, Tasca CI. G protein-coupled receptor oligomerization and brain integration: focus on adenosinergic transmission. Brain Research. 1476: 86-95. PMID 22575562 DOI: 10.1016/J.Brainres.2012.04.056 |
0.563 |
|
| 2012 |
Borroto-Escuela DO, Romero-Fernandez W, Pérez-Alea M, Narvaez M, Tarakanov AO, Mudó G, Agnati LF, Ciruela F, Belluardo N, Fuxe K. The existence of FGFR1-5-HT1A receptor heterocomplexes in midbrain 5-HT neurons of the rat: relevance for neuroplasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6295-303. PMID 22553035 DOI: 10.1523/Jneurosci.4203-11.2012 |
0.393 |
|
| 2012 |
Fuxe K, Borroto-Escuela DO, Romero-Fernandez W, Ciruela F, Manger P, Leo G, DÃaz-Cabiale Z, Agnati LF. On the role of volume transmission and receptor-receptor interactions in social behaviour: focus on central catecholamine and oxytocin neurons. Brain Research. 1476: 119-31. PMID 22373652 DOI: 10.1016/J.Brainres.2012.01.062 |
0.38 |
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| 2012 |
Capdevila-Nortes X, López-Hernández T, Ciruela F, Estévez R. A modification of the split-tobacco etch virus method for monitoring interactions between membrane proteins in mammalian cells. Analytical Biochemistry. 423: 109-18. PMID 22342621 DOI: 10.1016/J.Ab.2012.01.022 |
0.349 |
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| 2012 |
Fuxe K, Borroto-Escuela DO, Marcellino D, Romero-Fernandez W, Frankowska M, Guidolin D, Filip M, Ferraro L, Woods AS, Tarakanov A, Ciruela F, Agnati LF, Tanganelli S. GPCR heteromers and their allosteric receptor-receptor interactions. Current Medicinal Chemistry. 19: 356-63. PMID 22335512 DOI: 10.2174/092986712803414259 |
0.551 |
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| 2012 |
Fernández-Dueñas V, Poveda R, Sánchez S, Ciruela F. Synergistic interaction between fentanyl and a tramadol: paracetamol combination on the inhibition of nociception in mice. Journal of Pharmacological Sciences. 118: 299-302. PMID 22302020 DOI: 10.1254/Jphs.11161Sc |
0.662 |
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| 2012 |
Guescini M, Leo G, Genedani S, Carone C, Pederzoli F, Ciruela F, Guidolin D, Stocchi V, Mantuano M, Borroto-Escuela DO, Fuxe K, Agnati LF. Microvesicle and tunneling nanotube mediated intercellular transfer of g-protein coupled receptors in cell cultures. Experimental Cell Research. 318: 603-13. PMID 22266577 DOI: 10.1016/J.Yexcr.2012.01.005 |
0.392 |
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| 2012 |
Borroto-Escuela DO, Romero-Fernandez W, Mudó G, Pérez-Alea M, Ciruela F, Tarakanov AO, Narvaez M, Di Liberto V, Agnati LF, Belluardo N, Fuxe K. Fibroblast growth factor receptor 1- 5-hydroxytryptamine 1A heteroreceptor complexes and their enhancement of hippocampal plasticity. Biological Psychiatry. 71: 84-91. PMID 22035699 DOI: 10.1016/J.Biopsych.2011.09.012 |
0.454 |
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| 2012 |
Lujan R, Ciruela F. GABAB receptors-associated proteins: potential drug targets in neurological disorders? Current Drug Targets. 13: 129-44. PMID 22023408 DOI: 10.2174/138945012798868425 |
0.55 |
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| 2012 |
Borroto-Escuela DO, Agnati LF, Fuxe K, Ciruela F. Muscarinic acetylcholine receptor-interacting proteins (mAChRIPs): targeting the receptorsome. Current Drug Targets. 13: 53-71. PMID 22023407 DOI: 10.2174/138945012798868506 |
0.535 |
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| 2012 |
González S, Rangel-Barajas C, Peper M, Lorenzo R, Moreno E, Ciruela F, Borycz J, Ortiz J, LluÃs C, Franco R, McCormick PJ, Volkow ND, Rubinstein M, Floran B, Ferré S. Dopamine D4 receptor, but not the ADHD-associated D4.7 variant, forms functional heteromers with the dopamine D2S receptor in the brain. Molecular Psychiatry. 17: 650-62. PMID 21844870 DOI: 10.1038/Mp.2011.93 |
0.438 |
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| 2012 |
Ciruela F. G protein-coupled receptors interacting proteins: towards the druggable interactome. Current Drug Targets. 13: 1-2. PMID 21777189 DOI: 10.2174/138945012798868443 |
0.432 |
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| 2012 |
Ciruela F. Editorial: G protein-coupled receptors interacting proteins: Towards the druggable interactome Current Drug Targets. 13: 1-2. DOI: 10.2174/138945012798868443 |
0.32 |
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| 2011 |
Borroto-Escuela DO, Romero-Fernandez W, GarcÃa-Negredo G, Correia PA, Garriga P, Fuxe K, Ciruela F. Dissecting the conserved NPxxY motif of the M3 muscarinic acetylcholine receptor: critical role of Asp-7.49 for receptor signaling and multiprotein complex formation. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 28: 1009-22. PMID 22178951 DOI: 10.1159/000335788 |
0.494 |
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| 2011 |
Agnati LF, Guidolin D, Leo G, Guescini M, Pizzi M, Stocchi V, Spano PF, Ghidoni R, Ciruela F, Genedani S, Fuxe K. Possible new targets for GPCR modulation: allosteric interactions, plasma membrane domains, intercellular transfer and epigenetic mechanisms. Journal of Receptor and Signal Transduction Research. 31: 315-31. PMID 21929287 DOI: 10.3109/10799893.2011.599393 |
0.434 |
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| 2011 |
Vallano A, Fernandez-Duenas V, Pedros C, Arnau JM, Ciruela F. An update on adenosine A2A receptors as drug target in Parkinson's disease. Cns & Neurological Disorders Drug Targets. 10: 659-69. PMID 21838670 DOI: 10.2174/187152711797247803 |
0.774 |
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| 2011 |
Sahlholm K, Barchad-Avitzur O, Marcellino D, Gómez-Soler M, Fuxe K, Ciruela F, Arhem P. Agonist-specific voltage sensitivity at the dopamine D2S receptor--molecular determinants and relevance to therapeutic ligands. Neuropharmacology. 61: 937-49. PMID 21752340 DOI: 10.1016/J.Neuropharm.2011.06.022 |
0.822 |
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| 2011 |
Borroto-Escuela DO, Tarakanov AO, Guidolin D, Ciruela F, Agnati LF, Fuxe K. Moonlighting characteristics of G protein-coupled receptors: focus on receptor heteromers and relevance for neurodegeneration. Iubmb Life. 63: 463-72. PMID 21698749 DOI: 10.1002/Iub.473 |
0.497 |
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| 2011 |
López-Hernández T, Sirisi S, Capdevila-Nortes X, Montolio M, Fernández-Dueñas V, Scheper GC, van der Knaap MS, Casquero P, Ciruela F, Ferrer I, Nunes V, Estévez R. Molecular mechanisms of MLC1 and GLIALCAM mutations in megalencephalic leukoencephalopathy with subcortical cysts. Human Molecular Genetics. 20: 3266-77. PMID 21624973 DOI: 10.1093/Hmg/Ddr238 |
0.614 |
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| 2011 |
Romero-Fernandez W, Borroto-Escuela DO, Tarakanov AO, Mudó G, Narvaez M, Pérez-Alea M, Agnati LF, Ciruela F, Belluardo N, Fuxe K. Agonist-induced formation of FGFR1 homodimers and signaling differ among members of the FGF family. Biochemical and Biophysical Research Communications. 409: 764-8. PMID 21621521 DOI: 10.1016/J.Bbrc.2011.05.085 |
0.356 |
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| 2011 |
Ciruela F. Adenosine receptors. Biochimica Et Biophysica Acta. 1808: 1231-2. PMID 21444000 DOI: 10.1016/j.bbamem.2011.03.007 |
0.434 |
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| 2011 |
Caballero M, Núñez F, Ahern S, Cuffí ML, Carbonell L, Sánchez S, Fernández-Dueñas V, Ciruela F. Caffeine improves attention deficit in neonatal 6-OHDA lesioned rats, an animal model of attention deficit hyperactivity disorder (ADHD). Neuroscience Letters. 494: 44-8. PMID 21362462 DOI: 10.1016/J.Neulet.2011.02.050 |
0.623 |
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| 2011 |
Van Craenenbroeck K, Borroto-Escuela DO, Romero-Fernandez W, Skieterska K, Rondou P, Lintermans B, Vanhoenacker P, Fuxe K, Ciruela F, Haegeman G. Dopamine D4 receptor oligomerization--contribution to receptor biogenesis. The Febs Journal. 278: 1333-44. PMID 21320289 DOI: 10.1111/J.1742-4658.2011.08052.X |
0.444 |
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| 2011 |
Ciruela F, Gómez-Soler M, Guidolin D, Borroto-Escuela DO, Agnati LF, Fuxe K, Fernández-Dueñas V. Adenosine receptor containing oligomers: their role in the control of dopamine and glutamate neurotransmission in the brain. Biochimica Et Biophysica Acta. 1808: 1245-55. PMID 21316336 DOI: 10.1016/J.Bbamem.2011.02.007 |
0.573 |
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| 2011 |
Fernández-Dueñas V, Poveda R, Fernández A, Sánchez S, Planas E, Ciruela F. Fentanyl-trazodone-paracetamol triple drug combination: multimodal analgesia in a mouse model of visceral pain. Pharmacology, Biochemistry, and Behavior. 98: 331-6. PMID 21296105 DOI: 10.1016/J.Pbb.2011.01.023 |
0.665 |
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| 2011 |
Borroto-Escuela DO, Romero-Fernandez W, Tarakanov AO, Ciruela F, Agnati LF, Fuxe K. On the existence of a possible A2A-D2-β-Arrestin2 complex: A2A agonist modulation of D2 agonist-induced β-arrestin2 recruitment. Journal of Molecular Biology. 406: 687-99. PMID 21256133 DOI: 10.1016/J.Jmb.2011.01.022 |
0.347 |
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| 2011 |
Borroto-Escuela DO, Correia PA, Romero-Fernandez W, Narvaez M, Fuxe K, Ciruela F, Garriga P. Muscarinic receptor family interacting proteins: role in receptor function. Journal of Neuroscience Methods. 195: 161-9. PMID 21134400 DOI: 10.1016/J.Jneumeth.2010.11.025 |
0.546 |
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| 2011 |
Guidolin D, Ciruela F, Genedani S, Guescini M, Tortorella C, Albertin G, Fuxe K, Agnati LF. Bioinformatics and mathematical modelling in the study of receptor-receptor interactions and receptor oligomerization: focus on adenosine receptors. Biochimica Et Biophysica Acta. 1808: 1267-83. PMID 20888789 DOI: 10.1016/J.Bbamem.2010.09.022 |
0.562 |
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| 2011 |
Gómez-Soler M, Ahern S, Fernández-Dueñas V, Ciruela F. On the role of G protein-coupled receptors oligomerization Open Biology Journal. 4: 47-53. DOI: 10.2174/1874196701104010047 |
0.532 |
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| 2010 |
Vilardaga JP, Agnati LF, Fuxe K, Ciruela F. G-protein-coupled receptor heteromer dynamics. Journal of Cell Science. 123: 4215-20. PMID 21123619 DOI: 10.1242/Jcs.063354 |
0.497 |
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| 2010 |
Borroto-Escuela DO, Romero-Fernandez W, Tarakanov AO, Marcellino D, Ciruela F, Agnati LF, Fuxe K. Dopamine D2 and 5-hydroxytryptamine 5-HT(â‚‚A) receptors assemble into functionally interacting heteromers. Biochemical and Biophysical Research Communications. 401: 605-10. PMID 20888323 DOI: 10.1016/J.Bbrc.2010.09.110 |
0.322 |
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| 2010 |
Ciruela F, Fernández-Dueñas V, Sahlholm K, Fernández-Alacid L, Nicolau JC, Watanabe M, Luján R. Evidence for oligomerization between GABAB receptors and GIRK channels containing the GIRK1 and GIRK3 subunits. The European Journal of Neuroscience. 32: 1265-77. PMID 20846323 DOI: 10.1111/J.1460-9568.2010.07356.X |
0.719 |
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| 2010 |
Ciruela F, Vallano A, Arnau JM, Sánchez S, Borroto-Escuela DO, Agnati LF, Fuxe K, Fernández-Dueñas V. G protein-coupled receptor oligomerization for what? Journal of Receptor and Signal Transduction Research. 30: 322-30. PMID 20718634 DOI: 10.3109/10799893.2010.508166 |
0.536 |
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| 2010 |
Fuxe K, Marcellino D, Borroto-Escuela DO, Frankowska M, Ferraro L, Guidolin D, Ciruela F, Agnati LF. The changing world of G protein-coupled receptors: from monomers to dimers and receptor mosaics with allosteric receptor-receptor interactions. Journal of Receptor and Signal Transduction Research. 30: 272-83. PMID 20684666 DOI: 10.3109/10799893.2010.506191 |
0.55 |
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| 2010 |
Ciruela F, Vilardaga JP, Fernández-Dueñas V. Lighting up multiprotein complexes: lessons from GPCR oligomerization. Trends in Biotechnology. 28: 407-15. PMID 20542584 DOI: 10.1016/J.Tibtech.2010.05.002 |
0.687 |
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| 2010 |
Agnati LF, Guidolin D, Albertin G, Trivello E, Ciruela F, Genedani S, Tarakanov A, Fuxe K. An integrated view on the role of receptor mosaics at perisynaptic level: focus on adenosine A(2A), dopamine D(2), cannabinoid CB(1), and metabotropic glutamate mGlu(5) receptors. Journal of Receptor and Signal Transduction Research. 30: 355-69. PMID 20524778 DOI: 10.3109/10799893.2010.487492 |
0.551 |
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| 2010 |
Fernández-Dueñas V, Ciruela F, Gandía J, Sánchez S, Planas E, Poveda R. Histamine H3 receptor activation potentiates peripheral opioid-mediated antinociception: substance P role in peripheral inflammation in mice. European Journal of Pharmacology. 638: 72-7. PMID 20435034 DOI: 10.1016/J.Ejphar.2010.04.022 |
0.809 |
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| 2010 |
Agnati LF, Guidolin D, Vilardaga JP, Ciruela F, Fuxe K. On the expanding terminology in the GPCR field: the meaning of receptor mosaics and receptor heteromers. Journal of Receptor and Signal Transduction Research. 30: 287-303. PMID 20429829 DOI: 10.3109/10799891003786226 |
0.508 |
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| 2010 |
Borroto-Escuela DO, GarcÃa-Negredo G, Garriga P, Fuxe K, Ciruela F. The M(5) muscarinic acetylcholine receptor third intracellular loop regulates receptor function and oligomerization. Biochimica Et Biophysica Acta. 1803: 813-25. PMID 20398705 DOI: 10.1016/J.Bbamcr.2010.04.002 |
0.492 |
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| 2010 |
MartÃn R, Durroux T, Ciruela F, Torres M, Pin JP, Sánchez-Prieto J. The metabotropic glutamate receptor mGlu7 activates phospholipase C, translocates munc-13-1 protein, and potentiates glutamate release at cerebrocortical nerve terminals. The Journal of Biological Chemistry. 285: 17907-17. PMID 20375012 DOI: 10.1074/Jbc.M109.080838 |
0.451 |
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| 2010 |
Fuxe K, Marcellino D, Borroto-Escuela DO, Guescini M, Fernández-Dueñas V, Tanganelli S, Rivera A, Ciruela F, Agnati LF. Adenosine-dopamine interactions in the pathophysiology and treatment of CNS disorders. Cns Neuroscience & Therapeutics. 16: e18-42. PMID 20345970 DOI: 10.1111/J.1755-5949.2009.00126.X |
0.391 |
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| 2010 |
Borroto-Escuela DO, Correia PA, Perez Alea M, Narvaez M, Garriga P, Fuxe K, Ciruela F. Impaired M(3) muscarinic acetylcholine receptor signal transduction through blockade of binding of multiple proteins to its third intracellular loop. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 25: 397-408. PMID 20332620 DOI: 10.1159/000303044 |
0.459 |
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| 2010 |
Borroto-Escuela DO, Marcellino D, Narvaez M, Flajolet M, Heintz N, Agnati L, Ciruela F, Fuxe K. A serine point mutation in the adenosine A2AR C-terminal tail reduces receptor heteromerization and allosteric modulation of the dopamine D2R. Biochemical and Biophysical Research Communications. 394: 222-7. PMID 20197060 DOI: 10.1016/J.Bbrc.2010.02.168 |
0.342 |
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| 2010 |
Ciruela F, Albergaria C, Soriano A, Cuffí L, Carbonell L, Sánchez S, Gandía J, Fernández-Dueñas V. Adenosine receptors interacting proteins (ARIPs): Behind the biology of adenosine signaling. Biochimica Et Biophysica Acta. 1798: 9-20. PMID 19883624 DOI: 10.1016/J.Bbamem.2009.10.016 |
0.861 |
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| 2009 |
Canela L, Fernández-Dueñas V, Albergaria C, Watanabe M, Lluís C, Mallol J, Canela EI, Franco R, Luján R, Ciruela F. The association of metabotropic glutamate receptor type 5 with the neuronal Ca2+-binding protein 2 modulates receptor function. Journal of Neurochemistry. 111: 555-67. PMID 19694902 DOI: 10.1111/J.1471-4159.2009.06348.X |
0.849 |
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| 2009 |
Fernández-Alacid L, Aguado C, Ciruela F, MartÃn R, Colón J, Cabañero MJ, Gassmann M, Watanabe M, Shigemoto R, Wickman K, Bettler B, Sánchez-Prieto J, Luján R. Subcellular compartment-specific molecular diversity of pre- and post-synaptic GABA-activated GIRK channels in Purkinje cells. Journal of Neurochemistry. 110: 1363-76. PMID 19558451 DOI: 10.1111/J.1471-4159.2009.06229.X |
0.356 |
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| 2009 |
Cabello N, Gandía J, Bertarelli DC, Watanabe M, Lluís C, Franco R, Ferré S, Luján R, Ciruela F. Metabotropic glutamate type 5, dopamine D2 and adenosine A2a receptors form higher-order oligomers in living cells. Journal of Neurochemistry. 109: 1497-507. PMID 19344374 DOI: 10.1111/J.1471-4159.2009.06078.X |
0.855 |
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| 2009 |
Fernández-Dueñas V, Albergaria C, Sánchez S, Gandía J, Ciruela F. G protein-coupled receptor oligomerization in the basal ganglia and its implications in Parkinson's disease Methods and Findings in Experimental and Clinical Pharmacology. 31: 165-169. DOI: 10.1358/mf.2009.31.3.1362514 |
0.41 |
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| 2008 |
Navarro G, Carriba P, Gandía J, Ciruela F, Casadó V, Cortés A, Mallol J, Canela EI, Lluis C, Franco R. Detection of heteromers formed by cannabinoid CB1, dopamine D2, and adenosine A2A G-protein-coupled receptors by combining bimolecular fluorescence complementation and bioluminescence energy transfer. Thescientificworldjournal. 8: 1088-97. PMID 18956124 DOI: 10.1100/Tsw.2008.136 |
0.845 |
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| 2008 |
Briddon SJ, GandÃa J, Amaral OB, Ferré S, LluÃs C, Franco R, Hill SJ, Ciruela F. Plasma membrane diffusion of G protein-coupled receptor oligomers. Biochimica Et Biophysica Acta. 1783: 2262-8. PMID 18691614 DOI: 10.1016/J.Bbamcr.2008.07.006 |
0.722 |
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| 2008 |
Gandia J, Galino J, Amaral OB, Soriano A, Lluís C, Franco R, Ciruela F. Detection of higher-order G protein-coupled receptor oligomers by a combined BRET-BiFC technique. Febs Letters. 582: 2979-84. PMID 18675812 DOI: 10.1016/J.Febslet.2008.07.045 |
0.84 |
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| 2008 |
Ciruela F. Fluorescence-based methods in the study of protein-protein interactions in living cells. Current Opinion in Biotechnology. 19: 338-43. PMID 18602005 DOI: 10.1016/J.Copbio.2008.06.003 |
0.305 |
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| 2008 |
Carriba P, Navarro G, Ciruela F, Ferré S, Casadó V, Agnati L, Cortés A, Mallol J, Fuxe K, Canela EI, LluÃs C, Franco R. Detection of heteromerization of more than two proteins by sequential BRET-FRET. Nature Methods. 5: 727-33. PMID 18587404 DOI: 10.1038/Nmeth.1229 |
0.671 |
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| 2008 |
Ferré S, Quiroz C, Woods AS, Cunha R, Popoli P, Ciruela F, Lluis C, Franco R, Azdad K, Schiffmann SN. An update on adenosine A2A-dopamine D2 receptor interactions: implications for the function of G protein-coupled receptors. Current Pharmaceutical Design. 14: 1468-74. PMID 18537670 DOI: 10.2174/138161208784480108 |
0.518 |
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| 2008 |
Gandía J, Lluís C, Ferré S, Franco R, Ciruela F. Light resonance energy transfer-based methods in the study of G protein-coupled receptor oligomerization. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 30: 82-9. PMID 18081019 DOI: 10.1002/Bies.20682 |
0.775 |
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| 2008 |
Franco R, Casadó V, Cortés A, Mallol J, Ciruela F, Ferré S, Lluis C, Canela EI. G-protein-coupled receptor heteromers: function and ligand pharmacology. British Journal of Pharmacology. 153: S90-8. PMID 18037920 DOI: 10.1038/Sj.Bjp.0707571 |
0.528 |
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| 2008 |
Ferre S, Ciruela F, Borycz J, Solinas M, Quarta D, Antoniou K, Quiroz C, Justinova Z, Lluis C, Franco R, Goldberg SR. Adenosine A1-A2A receptor heteromers: new targets for caffeine in the brain. Frontiers in Bioscience : a Journal and Virtual Library. 13: 2391-9. PMID 17981720 DOI: 10.2741/2852 |
0.398 |
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| 2007 |
Ferré S, Ciruela F, Quiroz C, Luján R, Popoli P, Cunha RA, Agnati LF, Fuxe K, Woods AS, Lluis C, Franco R. Adenosine receptor heteromers and their integrative role in striatal function. Thescientificworldjournal. 7: 74-85. PMID 17982579 DOI: 10.1100/Tsw.2007.211 |
0.547 |
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| 2007 |
Ladera C, Godino Mdel C, MartÃn R, Luján R, Shigemoto R, Ciruela F, Torres M, Sánchez-Prieto J. The coexistence of multiple receptors in a single nerve terminal provides evidence for pre-synaptic integration. Journal of Neurochemistry. 103: 2314-26. PMID 17944874 DOI: 10.1111/J.1471-4159.2007.04964.X |
0.44 |
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| 2007 |
Casadó V, Cortés A, Ciruela F, Mallol J, Ferré S, Lluis C, Canela EI, Franco R. Old and new ways to calculate the affinity of agonists and antagonists interacting with G-protein-coupled monomeric and dimeric receptors: the receptor-dimer cooperativity index. Pharmacology & Therapeutics. 116: 343-54. PMID 17935788 DOI: 10.1016/J.Pharmthera.2007.05.010 |
0.743 |
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| 2007 |
Ferré S, Ciruela F, Woods AS, Lluis C, Franco R. Functional relevance of neurotransmitter receptor heteromers in the central nervous system. Trends in Neurosciences. 30: 440-6. PMID 17692396 DOI: 10.1016/J.Tins.2007.07.001 |
0.526 |
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| 2007 |
Canela L, Luján R, Lluís C, Burgueño J, Mallol J, Canela EI, Franco R, Ciruela F. The neuronal Ca(2+) -binding protein 2 (NECAB2) interacts with the adenosine A(2A) receptor and modulates the cell surface expression and function of the receptor. Molecular and Cellular Neurosciences. 36: 1-12. PMID 17689978 DOI: 10.1016/J.Mcn.2007.05.007 |
0.838 |
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| 2007 |
Ferré S, Agnati LF, Ciruela F, Lluis C, Woods AS, Fuxe K, Franco R. Neurotransmitter receptor heteromers and their integrative role in 'local modules': the striatal spine module. Brain Research Reviews. 55: 55-67. PMID 17408563 DOI: 10.1016/J.Brainresrev.2007.01.007 |
0.533 |
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| 2007 |
Carriba P, Ortiz O, Patkar K, Justinova Z, Stroik J, Themann A, Müller C, Woods AS, Hope BT, Ciruela F, Casadó V, Canela EI, Lluis C, Goldberg SR, Moratalla R, et al. Striatal adenosine A2A and cannabinoid CB1 receptors form functional heteromeric complexes that mediate the motor effects of cannabinoids. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 2249-59. PMID 17356572 DOI: 10.1038/Sj.Npp.1301375 |
0.736 |
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| 2007 |
Cabello N, Remelli R, Canela L, Soriguera A, Mallol J, Canela EI, Robbins MJ, Lluis C, Franco R, McIlhinney RA, Ciruela F. Actin-binding protein alpha-actinin-1 interacts with the metabotropic glutamate receptor type 5b and modulates the cell surface expression and function of the receptor. The Journal of Biological Chemistry. 282: 12143-53. PMID 17311919 DOI: 10.1074/Jbc.M608880200 |
0.841 |
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| 2007 |
Franco R, Lluis C, Canela EI, Mallol J, Agnati L, Casadó V, Ciruela F, Ferré S, Fuxe K. Receptor-receptor interactions involving adenosine A1 or dopamine D1 receptors and accessory proteins. Journal of Neural Transmission (Vienna, Austria : 1996). 114: 93-104. PMID 17024327 DOI: 10.1007/S00702-006-0566-7 |
0.579 |
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| 2007 |
Giménez-Llort L, Schiffmann SN, Shmidt T, Canela L, Camón L, Wassholm M, Canals M, Terasmaa A, Fernández-Teruel A, Tobeña A, Popova E, Ferré S, Agnati L, Ciruela F, MartÃnez E, et al. Working memory deficits in transgenic rats overexpressing human adenosine A2A receptors in the brain. Neurobiology of Learning and Memory. 87: 42-56. PMID 16824773 DOI: 10.1016/J.Nlm.2006.05.004 |
0.792 |
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| 2007 |
Quarta D, Ciruela F, Patkar K, Borycz J, Solinas M, Lluis C, Franco R, Wise RA, Goldberg SR, Hope BT, Woods AS, Ferré S. Heteromeric nicotinic acetylcholine-dopamine autoreceptor complexes modulate striatal dopamine release. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 35-42. PMID 16710311 DOI: 10.1038/Sj.Npp.1301103 |
0.45 |
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| 2007 |
Hove-Madsen L, Prat-Vidal C, Llach A, Ciruela F, Casadó V, Lluis C, Bayes-Genis A, Cinca J, Franco R. Reply: Does the adenosine A2A receptor stimulate the ryanodine receptor? Cardiovascular Research. 73: 249-250. DOI: 10.1016/J.Cardiores.2006.11.011 |
0.397 |
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| 2006 |
Pacheco R, Oliva H, Martinez-Navío JM, Climent N, Ciruela F, Gatell JM, Gallart T, Mallol J, Lluis C, Franco R. Glutamate released by dendritic cells as a novel modulator of T cell activation. Journal of Immunology (Baltimore, Md. : 1950). 177: 6695-704. PMID 17082582 DOI: 10.4049/Jimmunol.177.10.6695 |
0.313 |
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| 2006 |
Ciruela F, Ferré S, Casadó V, Cortés A, Cunha RA, Lluis C, Franco R. Heterodimeric adenosine receptors: a device to regulate neurotransmitter release. Cellular and Molecular Life Sciences : Cmls. 63: 2427-31. PMID 17058035 DOI: 10.1007/S00018-006-6216-2 |
0.513 |
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| 2006 |
Hove-Madsen L, Prat-Vidal C, Llach A, Ciruela F, Casadó V, Lluis C, Bayes-Genis A, Cinca J, Franco R. Adenosine A2A receptors are expressed in human atrial myocytes and modulate spontaneous sarcoplasmic reticulum calcium release. Cardiovascular Research. 72: 292-302. PMID 17014834 DOI: 10.1016/J.Cardiores.2006.07.020 |
0.307 |
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| 2006 |
Franco R, Casadó V, Mallol J, Ferrada C, Ferré S, Fuxe K, Cortés A, Ciruela F, Lluis C, Canela EI. The two-state dimer receptor model: a general model for receptor dimers. Molecular Pharmacology. 69: 1905-12. PMID 16501032 DOI: 10.1124/Mol.105.020685 |
0.724 |
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| 2006 |
Ciruela F, Casadó V, Rodrigues RJ, Luján R, Burgueño J, Canals M, Borycz J, Rebola N, Goldberg SR, Mallol J, Cortés A, Canela EI, López-Giménez JF, Milligan G, Lluis C, et al. Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2080-7. PMID 16481441 DOI: 10.1523/Jneurosci.3574-05.2006 |
0.735 |
|
| 2005 |
Ciruela F, Canela L, Burgueño J, Soriguera A, Cabello N, Canela EI, Casadó V, Cortés A, Mallol J, Woods AS, Ferré S, Lluis C, Franco R. Heptaspanning membrane receptors and cytoskeletal/scaffolding proteins: focus on adenosine, dopamine, and metabotropic glutamate receptor function. Journal of Molecular Neuroscience : Mn. 26: 277-92. PMID 16012201 DOI: 10.1385/Jmn:26:2-3:277 |
0.836 |
|
| 2005 |
Franco R, Ciruela F, Casadó V, Cortes A, Canela EI, Mallol J, Agnati LF, Ferré S, Fuxe K, Lluis C. Partners for adenosine A1 receptors. Journal of Molecular Neuroscience : Mn. 26: 221-32. PMID 16012195 DOI: 10.1385/Jmn:26:2-3:221 |
0.747 |
|
| 2005 |
Woods AS, Ciruela F, Fuxe K, Agnati LF, Lluis C, Franco R, Ferré S. Role of electrostatic interaction in receptor-receptor heteromerization. Journal of Molecular Neuroscience : Mn. 26: 125-32. PMID 16012186 DOI: 10.1385/Jmn:26:2-3:125 |
0.529 |
|
| 2005 |
Franco R, Casadó V, Mallol J, Ferré S, Fuxe K, Cortés A, Ciruela F, Lluis C, Canela EI. Dimer-based model for heptaspanning membrane receptors. Trends in Biochemical Sciences. 30: 360-6. PMID 15951182 DOI: 10.1016/J.Tibs.2005.05.010 |
0.713 |
|
| 2004 |
Quarta D, Borycz J, Solinas M, Patkar K, Hockemeyer J, Ciruela F, Lluis C, Franco R, Woods AS, Goldberg SR, Ferré S. Adenosine receptor-mediated modulation of dopamine release in the nucleus accumbens depends on glutamate neurotransmission and N-methyl-D-aspartate receptor stimulation. Journal of Neurochemistry. 91: 873-80. PMID 15525341 DOI: 10.1111/J.1471-4159.2004.02761.X |
0.38 |
|
| 2004 |
Burgueño J, Canela EI, Mallol J, Lluis C, Franco R, Ciruela F. Mutual regulation between metabotropic glutamate type 1alpha receptor and caveolin proteins: from traffick to constitutive activity. Experimental Cell Research. 300: 23-34. PMID 15383311 DOI: 10.1016/J.Yexcr.2004.06.013 |
0.854 |
|
| 2004 |
Ciruela F, Burgueño J, Casadó V, Canals M, Marcellino D, Goldberg SR, Bader M, Fuxe K, Agnati LF, Lluis C, Franco R, Ferré S, Woods AS. Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2A and dopamine D2 receptors. Analytical Chemistry. 76: 5354-63. PMID 15362892 DOI: 10.1021/Ac049295F |
0.468 |
|
| 2004 |
Ferré S, Ciruela F, Canals M, Marcellino D, Burgueno J, Casadó V, Hillion J, Torvinen M, Fanelli F, Benedetti Pd Pd, Goldberg SR, Bouvier M, Fuxe K, Agnati LF, Lluis C, et al. Adenosine A2A-dopamine D2 receptor-receptor heteromers. Targets for neuro-psychiatric disorders. Parkinsonism & Related Disorders. 10: 265-71. PMID 15196504 DOI: 10.1016/J.Parkreldis.2004.02.014 |
0.833 |
|
| 2004 |
Pacheco R, Ciruela F, Casadó V, Mallol J, Gallart T, Lluis C, Franco R. Group I metabotropic glutamate receptors mediate a dual role of glutamate in T cell activation Journal of Biological Chemistry. 279: 33352-33358. PMID 15184389 DOI: 10.1074/Jbc.M401761200 |
0.393 |
|
| 2004 |
Canals M, Burgueño J, Marcellino D, Cabello N, Canela EI, Mallol J, Agnati L, Ferré S, Bouvier M, Fuxe K, Ciruela F, Lluis C, Franco R. Homodimerization of adenosine A2A receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer. Journal of Neurochemistry. 88: 726-34. PMID 14720222 DOI: 10.1046/J.1471-4159.2003.02200.X |
0.847 |
|
| 2003 |
Fuxe K, Agnati LF, Jacobsen K, Hillion J, Canals M, Torvinen M, Tinner-Staines B, Staines W, Rosin D, Terasmaa A, Popoli P, Leo G, Vergoni V, Lluis C, Ciruela F, et al. Receptor heteromerization in adenosine A2A receptor signaling: relevance for striatal function and Parkinson's disease. Neurology. 61: S19-23. PMID 14663004 DOI: 10.1212/01.Wnl.0000095206.44418.5C |
0.561 |
|
| 2003 |
Canals M, Marcellino D, Fanelli F, Ciruela F, de Benedetti P, Goldberg SR, Neve K, Fuxe K, Agnati LF, Woods AS, Ferré S, Lluis C, Bouvier M, Franco R. Adenosine A2A-dopamine D2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer. The Journal of Biological Chemistry. 278: 46741-9. PMID 12933819 DOI: 10.1074/Jbc.M306451200 |
0.533 |
|
| 2003 |
Burgueño J, Enrich C, Canela EI, Mallol J, Lluis C, Franco R, Ciruela F. Metabotropic glutamate type 1α receptor localizes in low-density caveolin-rich plasma membrane fractions Journal of Neurochemistry. 86: 785-791. PMID 12887677 DOI: 10.1046/J.1471-4159.2003.01842.X |
0.845 |
|
| 2003 |
Burgueño J, Blake DJ, Benson MA, Tinsley CL, Esapa CT, Canela EI, Penela P, Mallol J, Mayor F, Lluis C, Franco R, Ciruela F. The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin. The Journal of Biological Chemistry. 278: 37545-52. PMID 12837758 DOI: 10.1074/Jbc.M302809200 |
0.735 |
|
| 2003 |
Franco R, Canals M, Marcellino D, Ferré S, Agnati L, Mallol J, Casadó V, Ciruela F, Fuxe K, Lluis C, Canela EI. Regulation of heptaspanning-membrane-receptor function by dimerization and clustering. Trends in Biochemical Sciences. 28: 238-43. PMID 12765835 DOI: 10.1016/S0968-0004(03)00065-3 |
0.738 |
|
| 2003 |
Escriche M, Burgueño J, Ciruela F, Canela EI, Mallol J, Enrich C, Lluís C, Franco R. Ligand-induced caveolae-mediated internalization of A1 adenosine receptors: Morphological evidence of endosomal sorting and receptor recycling Experimental Cell Research. 285: 72-90. PMID 12681288 DOI: 10.1016/S0014-4827(02)00090-3 |
0.847 |
|
| 2003 |
Ferré S, Ciruela F, Woods AS, Canals M, Burgueno J, Marcellino D, Karcz-Kubicha M, Hope BT, Morales M, Popoli P, Goldberg SR, Fuxe K, Lluis C, Franco R, Agnati L. Glutamate mGlu5-adenosine A2A-dopamine D2 receptor interactions in the striatum. Implications for drug therapy in neuro-psychiatric disorders and drug abuse Current Medicinal Chemistry - Central Nervous System Agents. 3: 1-26. DOI: 10.2174/1568015033357779 |
0.409 |
|
| 2002 |
Ferré S, Karcz-Kubicha M, Hope BT, Popoli P, Burgueño J, Gutiérrez MA, Casadó V, Fuxe K, Goldberg SR, Lluis C, Franco R, Ciruela F. Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: implications for striatal neuronal function. Proceedings of the National Academy of Sciences of the United States of America. 99: 11940-5. PMID 12189203 DOI: 10.1073/Pnas.172393799 |
0.525 |
|
| 2002 |
Torvinen M, Ginés S, Hillion J, Latini S, Canals M, Ciruela F, Bordoni F, Staines W, Pedata F, Agnati LF, Lluis C, Franco R, Ferré S, Fuxe K. Interactions among adenosine deaminase, adenosine A(1) receptors and dopamine D(1) receptors in stably cotransfected fibroblast cells and neurons. Neuroscience. 113: 709-19. PMID 12150791 DOI: 10.1016/S0306-4522(02)00058-1 |
0.533 |
|
| 2001 |
Luján R, Ciruela F. Immunocytochemical localization of metabotropic glutamate receptor type 1α and tubulin in rat brain Neuroreport. 12: 1285-1291. PMID 11338208 DOI: 10.1097/00001756-200105080-00046 |
0.416 |
|
| 2001 |
Ginés S, Ciruela F, Burgueño J, Casadó V, Canela EI, Mallol J, Lluís C, Franco R. Involvement of caveolin in ligand-induced recruitment and internalization of A1 adenosine receptor and adenosine deaminase in an epithelial cell line Molecular Pharmacology. 59: 1314-1323. PMID 11306717 |
0.363 |
|
| 2001 |
Ciruela F, Escriche M, Burgueño J, Angulo E, Casadó V, Soloviev MM, Canela EI, Mallol J, Chan WY, Lluis C, McIlhinney RAJ, Franco R. Metabotropic Glutamate 1α and Adenosine A1 Receptors Assemble into Functionally Interacting Complexes Journal of Biological Chemistry. 276: 18345-18351. PMID 11278325 DOI: 10.1074/Jbc.M006960200 |
0.546 |
|
| 2001 |
Chan WY, Soloviev MM, Ciruela F, McIlhinney RAJ. Molecular determinants of metabotropic glutamate receptor 1B trafficking Molecular and Cellular Neuroscience. 17: 577-588. PMID 11273651 DOI: 10.1006/Mcne.2001.0965 |
0.418 |
|
| 2001 |
Ciruela F, Jeffrey McIlhinney RA. Metabotropic glutamate receptor type 1α and tubulin assemble into dynamic interacting complexes Journal of Neurochemistry. 76: 750-757. PMID 11158246 DOI: 10.1046/J.1471-4159.2001.00099.X |
0.529 |
|
| 2001 |
Herrera C, Casadó V, Ciruela F, Schofield P, Mallol J, Lluis C, Franco R. Adenosine A2B receptors behave as an alternative anchoring protein for cell surface adenosine deaminase in lymphocytes and cultured cells Molecular Pharmacology. 59: 127-134. PMID 11125033 |
0.33 |
|
| 2001 |
Ginés S, Ciruela F, Burgueño J, Casadó V, Canela EI, Mallol J, Lluı́s C, Franco R. Involvement of Caveolin in Ligand-Induced Recruitment and Internalization of A1 Adenosine Receptor and Adenosine Deaminase in an Epithelial Cell Line Molecular Pharmacology. 59: 1314-1323. DOI: 10.1124/MOL.59.5.1314 |
0.314 |
|
| 2001 |
Herrera C, Casadó V, Ciruela F, Schofield P, Mallol J, Lluis C, Franco R. Adenosine A2B receptors behave as an alternative anchoring protein for cell surface adenosine deaminase in lymphocytes and cultured cells. Molecular Pharmacology. 59: 127-134. DOI: 10.1124/Mol.59.1.127 |
0.446 |
|
| 2001 |
Ciruela F, Escriche M, Soloviev MM, Canela EI, Burgeño J, Mallol J, Chan WY, Lluis C, McIlhinney RAJ, Franco R. Adenosine-glutamate receptor-receptor interactions in the central nervous system Drug Development Research. 52: 316-322. DOI: 10.1002/Ddr.1129 |
0.517 |
|
| 2001 |
Franco R, Ferré S, Torvinen M, Ginés S, Hillion J, Ciruela F, Canela EI, Mallol J, Casadó V, Lluis C, Fuxe K. Adenosine/dopamine receptor-receptor interactions in the central nervous system Drug Development Research. 52: 296-302. DOI: 10.1002/Ddr.1127 |
0.577 |
|
| 2000 |
White JH, McIllhinney RAJ, Wise A, Ciruela F, Chan WY, Emson PC, Billinton A, Marshall FH. The GABA(B) receptor interacts directly with the related transcription factors CREB2 and ATFx Proceedings of the National Academy of Sciences of the United States of America. 97: 13967-13972. PMID 11087824 DOI: 10.1073/Pnas.240452197 |
0.382 |
|
| 2000 |
Sarrió S, Casadó V, Escriche M, Ciruela F, Mallol J, Canela EI, Lluis C, Franco R. The heat shock cognate protein hsc73 assembles with adenosine receptors to form functional modules in the cell membrane Molecular and Cellular Biology. 20: 5164-5174. PMID 10866672 DOI: 10.1128/Mcb.20.14.5164-5174.2000 |
0.518 |
|
| 2000 |
Ciruela F, Soloviev MM, Chan WY, McIlhinney RAJ. Homer-1c/Vesl-1L modulates the cell surface targeting of metabotropic glutamate receptor type 1α: Evidence for an anchoring function Molecular and Cellular Neurosciences. 15: 36-50. PMID 10662504 DOI: 10.1006/Mcne.1999.0808 |
0.425 |
|
| 2000 |
Soloviev MM, Ciruela F, Chan WY, McIlhinney RAJ. Molecular characterisation of two structurally distinct groups of human Homers, generated by extensive alternative splicing Journal of Molecular Biology. 295: 1185-1200. PMID 10653696 DOI: 10.1006/Jmbi.1999.3436 |
0.391 |
|
| 1999 |
Ciruela F, Giacometti A, McIlhinney RAJ. Functional regulation of metabotropic glutamate receptor type 1c: A role for phosphorylation in the desensitization of the receptor Febs Letters. 462: 278-282. PMID 10622711 DOI: 10.1016/S0014-5793(99)01547-1 |
0.489 |
|
| 1999 |
Ciruela F, Soloviev MM, Mcilhinney RAJ. Co-expression of metabotropic glutamate receptor type 1α with Homer-1a/Vesl-1S increases the cell surface expression of the receptor Biochemical Journal. 341: 795-803. PMID 10417346 DOI: 10.1042/0264-6021:3410795 |
0.305 |
|
| 1999 |
Ciruela F, Soloviev MM, McIlhinney RAJ. Cell surface expression of the metabotropic glutamate receptor type 1α is regulated by the C-terminal tail Febs Letters. 448: 91-94. PMID 10217416 DOI: 10.1016/S0014-5793(99)00341-5 |
0.399 |
|
| 1999 |
Ciruela F, Robbins MJ, Willis AC, McIlhinney RAJ. Interactions of the C terminus of metabotropic glutamate receptor type 1α with rat brain proteins: Evidence for a direct interaction with tubulin Journal of Neurochemistry. 72: 346-354. PMID 9886087 DOI: 10.1046/J.1471-4159.1999.0720346.X |
0.408 |
|
| 1999 |
Ciruela F, Soloviev MM, McIlhinney RAJ. Effect of Homer-1a in the cell surface targeting of metabotropic glutamate receptor type 1α Biochemical Society Transactions. 27. DOI: 10.1042/Bst027A113B |
0.4 |
|
| 1999 |
Ciruela F, Soloviev MM, McILHINNEY RAJ. Co-expression of metabotropic glutamate receptor type 1alpha with homer-1a/Vesl-1S increases the cell surface expression of the receptor. Biochemical Journal. 341: 795-803. DOI: 10.1042/Bj3410795 |
0.417 |
|
| 1998 |
Franco R, Mallol J, Casadó V, Lluis C, Canela EI, Saura C, Blanco J, Ciruela F. Ecto-adenosine deaminase: An ecto-enzyme and a costimulatory protein acting on a variety of cell surface receptors Drug Development Research. 45: 261-268. DOI: 10.1002/(Sici)1098-2299(199811/12)45:3/4<261::Aid-Ddr24>3.0.Co;2-M |
0.334 |
|
| 1997 |
Ciruela F, McIlhinney RAJ. Differential internalisation of mGluR1 splice variants in response to agonist and phorbol esters in permanently transfected BHK cells Febs Letters. 418: 83-86. PMID 9414100 DOI: 10.1016/S0014-5793(97)01353-7 |
0.401 |
|
| 1997 |
Ciruela F, Saura C, Canela EI, Mallol J, Lluís C, Franco R. Ligand-induced phosphorylation, clustering, and desensitization of A1 adenosine receptors Molecular Pharmacology. 52: 788-797. PMID 9351969 DOI: 10.1124/Mol.52.5.788 |
0.475 |
|
| 1997 |
Franco R, Casadó V, Ciruela F, Saura C, Mallol J, Canela EI, Lluis C. Cell surface adenosine deaminase: Much more than an ectoenzyme Progress in Neurobiology. 52: 283-294. PMID 9247966 DOI: 10.1016/S0301-0082(97)00013-0 |
0.396 |
|
| 1997 |
Kontny E, Ciruela F, Svenningsson P, Ibáñez CF, Fredholm BB. On the role of the low-affinity neurotrophin receptor p75LNTR in nerve growth factor induction of differentiation and AP 1 binding activity in PC12 cells. Journal of Molecular Neuroscience : Mn. 8: 29-44. PMID 9061613 DOI: 10.1007/Bf02736861 |
0.49 |
|
| 1996 |
Saura C, Ciruela F, Casadó V, Canela EI, Mallol J, Lluis C, Franco R. Adenosine deaminase interacts with A1 adenosine receptors in pig brain cortical membranes Journal of Neurochemistry. 66: 1675-1682. PMID 8627325 DOI: 10.1046/J.1471-4159.1996.66041675.X |
0.49 |
|
| 1996 |
Franco R, Casadó V, Ciruela F, Mallol J, Lluis C, Canela EI. The cluster-arranged cooperative model: A model that accounts for the kinetics of binding to A1 adenosine receptors Biochemistry. 35: 3007-3015. PMID 8608139 DOI: 10.1021/Bi952415G |
0.451 |
|
| 1996 |
Ciruela F, Saura C, Canela EI, Mallol J, Lluis C, Franco R. Adenosine deaminase affects ligand-induced signalling by interacting with cell surface adenosine receptors Febs Letters. 380: 219-223. PMID 8601428 DOI: 10.1016/0014-5793(96)00023-3 |
0.44 |
|
| 1995 |
Ciruela F, Casado V, Mallol J, Canela EI, Lluis C, Franco R. Immunological identification of A1 adenosine receptors in brain cortex Journal of Neuroscience Research. 42: 818-828. PMID 8847743 DOI: 10.1002/Jnr.490420610 |
0.473 |
|
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