Jon W. Johnson - Publications

University of Pittsburgh, Pittsburgh, PA, United States 

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Phillips MB, Nigam A, Johnson JW. Interplay between Gating and Block of Ligand-Gated Ion Channels. Brain Sciences. 10. PMID 33271923 DOI: 10.3390/brainsci10120928  0.652
2020 Krall RF, Moutal A, Phillips MB, Asraf H, Johnson JW, Khanna R, Hershfinkel M, Aizenman E, Tzounopoulos T. Synaptic zinc inhibition of NMDA receptors depends on the association of GluN2A with the zinc transporter ZnT1. Science Advances. 6. PMID 32937457 DOI: 10.1126/Sciadv.Abb1515  0.653
2019 Povysheva N, Nigam A, Brisbin AK, Johnson JW, Barrionuevo G. Oxygen-Glucose Deprivation Differentially Affects Neocortical Pyramidal Neurons and Parvalbumin-Positive Interneurons. Neuroscience. PMID 31152933 DOI: 10.1016/j.neuroscience.2019.05.042  0.317
2018 Glasgow NG, Wilcox MR, Johnson JW. Effects of Mg on recovery of NMDA receptors from inhibition by memantine and ketamine reveal properties of a second site. Neuropharmacology. 137: 344-358. PMID 29793153 DOI: 10.1016/J.Neuropharm.2018.05.017  0.816
2018 Leiva R, Phillips MB, Turcu AL, Gratacòs-Batlle E, León-García L, Sureda FX, Soto D, Johnson JW, Vazquez S. Pharmacological and electrophysiological characterization of novel NMDA receptor antagonists. Acs Chemical Neuroscience. PMID 29767953 DOI: 10.1021/Acschemneuro.8B00154  0.733
2017 Wu M, White HV, Boehm B, Meriney CJ, Kerrigan K, Frasso M, Liang M, Gotway EM, Wilcox M, Johnson JW, Wipf P, Meriney SD. New Cav2 calcium channel gating modifiers with agonist activity and therapeutic potential to treat neuromuscular disease. Neuropharmacology. PMID 29246857 DOI: 10.1016/J.Neuropharm.2017.12.022  0.349
2017 Lorenz-Guertin JM, Wilcox MR, Zhang M, Larsen MB, Pilli J, Schmidt BF, Bruchez MP, Johnson JW, Waggoner AS, Watkins SC, Jacob TC. A versatile optical tool for studying synaptic GABAA receptor trafficking. Journal of Cell Science. PMID 29025969 DOI: 10.1242/Jcs.205286  0.387
2017 Glasgow NG, Povysheva NV, Azofeifa AM, Johnson JW. Memantine and ketamine differentially alter NMDA receptor desensitization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28877967 DOI: 10.1523/Jneurosci.1173-17.2017  0.83
2017 Divito CB, Borowski JE, Glasgow NG, Gonzalez-Suarez AD, Torres-Salazar D, Johnson JW, Amara SG. Glial and Neuronal Glutamate Transporters Differ in the Na(+) Requirements for Activation of the Substrate-Independent Anion Conductance. Frontiers in Molecular Neuroscience. 10: 150. PMID 28611584 DOI: 10.3389/Fnmol.2017.00150  0.8
2017 Mesbahi-Vasey S, Veras L, Yonkunas M, Johnson JW, Kurnikova MG. All atom NMDA receptor transmembrane domain model development and simulations in lipid bilayers and water. Plos One. 12: e0177686. PMID 28582391 DOI: 10.1371/Journal.Pone.0177686  0.72
2017 Sayede Mesbahi S, Johnson JW, Kurnikova M. Modeling Ion Selectivity in Transmembrane Domain of the NMDA Receptor Biophysical Journal. 112: 423a. DOI: 10.1016/J.Bpj.2016.11.2262  0.7
2016 Khlestova E, Johnson JW, Krystal JH, Lisman J. The Role of GluN2C-Containing NMDA Receptors in Ketamine's Psychotogenic Action and in Schizophrenia Models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 11151-11157. PMID 27807157 DOI: 10.1523/Jneurosci.1203-16.2016  0.42
2016 Povysheva NV, Johnson JW. Effects of memantine on the excitation-inhibition balance in prefrontal cortex. Neurobiology of Disease. PMID 27546057 DOI: 10.1016/j.nbd.2016.08.006  0.405
2016 Wilcox MR, Glasgow NG, Johnson JW. Functional Roles of a Conserved Tryptophan at Subunit-Subunit Interfaces in NMDA Receptor Membrane Regions Biophysical Journal. 110: 288a. DOI: 10.1016/J.Bpj.2015.11.1559  0.801
2015 Chen M, Tian S, Glasgow NG, Gibson G, Yang X, Shiber CE, Funderburgh J, Watkins S, Johnson JW, Schuman JS, Liu H. Lgr5(+) amacrine cells possess regenerative potential in the retina of adult mice. Aging Cell. 14: 635-43. PMID 25990970 DOI: 10.1111/Acel.12346  0.745
2015 Glasgow NG, Siegler Retchless B, Johnson JW. Molecular bases of NMDA receptor subtype-dependent properties. The Journal of Physiology. 593: 83-95. PMID 25556790 DOI: 10.1113/Jphysiol.2014.273763  0.837
2015 Johnson JW, Glasgow NG, Povysheva NV. Recent insights into the mode of action of memantine and ketamine. Current Opinion in Pharmacology. 20: 54-63. PMID 25462293 DOI: 10.1016/J.Coph.2014.11.006  0.834
2015 Mesbahi S, Veras L, Johnson JW, Kurnikova M. NMDA Receptor Transmembrane Domain: Structure and Mechanism of Ion Selectivity Biophysical Journal. 108: 384a. DOI: 10.1016/J.Bpj.2014.11.2107  0.722
2014 D'Aiuto L, Zhi Y, Kumar Das D, Wilcox MR, Johnson JW, McClain L, MacDonald ML, Di Maio R, Schurdak ME, Piazza P, Viggiano L, Sweet R, Kinchington PR, Bhattacharjee AG, Yolken R, et al. Large-scale generation of human iPSC-derived neural stem cells/early neural progenitor cells and their neuronal differentiation. Organogenesis. 10: 365-77. PMID 25629202 DOI: 10.1080/15476278.2015.1011921  0.325
2014 Glasgow NG, Siegler Retchless B, Johnson JW. Molecular bases of NMDA receptor subtype-dependent properties. The Journal of Physiology. PMID 25107930 DOI: 10.1113/jphysiol.2014.273763  0.4
2014 Glasgow NG, Johnson JW. Whole-cell patch-clamp analysis of recombinant NMDA receptor pharmacology using brief glutamate applications. Methods in Molecular Biology (Clifton, N.J.). 1183: 23-41. PMID 25023300 DOI: 10.1007/978-1-4939-1096-0_2  0.824
2014 Plowey ED, Johnson JW, Steer E, Zhu W, Eisenberg DA, Valentino NM, Liu YJ, Chu CT. Mutant LRRK2 enhances glutamatergic synapse activity and evokes excitotoxic dendrite degeneration. Biochimica Et Biophysica Acta. 1842: 1596-603. PMID 24874075 DOI: 10.1016/J.Bbadis.2014.05.016  0.779
2013 Kotermanski SE, Johnson JW, Thiels E. Comparison of behavioral effects of the NMDA receptor channel blockers memantine and ketamine in rats. Pharmacology, Biochemistry, and Behavior. 109: 67-76. PMID 23665480 DOI: 10.1016/J.Pbb.2013.05.005  0.794
2013 Clarke RJ, Glasgow NG, Johnson JW. Mechanistic and structural determinants of NMDA receptor voltage-dependent gating and slow Mg2+ unblock. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 4140-50. PMID 23447622 DOI: 10.1523/Jneurosci.3712-12.2013  0.817
2013 Abroshan H, Yonkunas M, Johnson JW, Kurnikova M. Glutamate Receptor Model and Atomistic Simulations; AMPA and NMDA Biophysical Journal. 104: 271a. DOI: 10.1016/J.Bpj.2012.11.1522  0.747
2012 Burton SD, Johnson JW, Zeringue HC, Meriney SD. Distinct roles of neuroligin-1 and SynCAM1 in synapse formation and function in primary hippocampal neuronal cultures. Neuroscience. 215: 1-16. PMID 22542674 DOI: 10.1016/J.Neuroscience.2012.04.047  0.317
2012 Siegler Retchless B, Gao W, Johnson JW. A single GluN2 subunit residue controls NMDA receptor channel properties via intersubunit interaction. Nature Neuroscience. 15: 406-13, S1-2. PMID 22246434 DOI: 10.1038/Nn.3025  0.463
2012 Povysheva NV, Johnson JW. Tonic NMDA receptor-mediated current in prefrontal cortical pyramidal cells and fast-spiking interneurons. Journal of Neurophysiology. 107: 2232-43. PMID 22236713 DOI: 10.1152/jn.01017.2011  0.372
2012 Ascher P, Johnson JW. The NMDA receptor, its channel, and its modulation by glycine The Nmda Receptor. DOI: 10.1093/acprof:oso/9780192625021.003.0007  0.674
2012 Veras L, Kurnikov I, Johnson JW, Kurnikova M. Computational Studies of the Molecular Mechanisms Responsible for Ca2+ Permeation and Mg2+ Block of NMDA Receptors Biophysical Journal. 102: 612a-613a. DOI: 10.1016/J.Bpj.2011.11.3340  0.743
2011 Goss JR, Cascio M, Goins WF, Huang S, Krisky DM, Clarke RJ, Johnson JW, Yokoyama H, Yoshimura N, Gold MS, Glorioso JC. HSV delivery of a ligand-regulated endogenous ion channel gene to sensory neurons results in pain control following channel activation. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 500-6. PMID 21081904 DOI: 10.1038/Mt.2010.246  0.597
2011 Veras L, Younkunas M, Hwang J, Kallenbach E, Kurnikov I, Johnson JW, Kurnikova M. Molecular Mechanisms of Ca2+ Selectivity and Mg2+ Block of NMDA Receptors Biophysical Journal. 100: 269a. DOI: 10.1016/J.Bpj.2010.12.1680  0.752
2009 Kotermanski SE, Wood JT, Johnson JW. Memantine binding to a superficial site on NMDA receptors contributes to partial trapping. The Journal of Physiology. 587: 4589-604. PMID 19687120 DOI: 10.1113/Jphysiol.2009.176297  0.838
2009 Gielen M, Siegler Retchless B, Mony L, Johnson JW, Paoletti P. Mechanism of differential control of NMDA receptor activity by NR2 subunits. Nature. 459: 703-7. PMID 19404260 DOI: 10.1038/Nature07993  0.655
2009 Kotermanski SE, Johnson JW. Mg2+ imparts NMDA receptor subtype selectivity to the Alzheimer's drug memantine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2774-9. PMID 19261873 DOI: 10.1523/Jneurosci.3703-08.2009  0.833
2009 Cascio M, Goss JR, Huang S, Krisky DM, Clarke RJ, Johnson JW, Glorioso JC. Targeted Delivery of Glycine Receptors to Peripheral Neurons as Treatment for Pain Biophysical Journal. 96: 487a. DOI: 10.1016/J.Bpj.2008.12.2511  0.614
2008 Clarke RJ, Johnson JW. Voltage-dependent gating of NR1/2B NMDA receptors. The Journal of Physiology. 586: 5727-41. PMID 18936081 DOI: 10.1113/Jphysiol.2008.160622  0.711
2008 Gielen M, Le Goff A, Stroebel D, Johnson JW, Neyton J, Paoletti P. Structural rearrangements of NR1/NR2A NMDA receptors during allosteric inhibition. Neuron. 57: 80-93. PMID 18184566 DOI: 10.1016/J.Neuron.2007.11.021  0.675
2006 Qian A, Johnson JW. Permeant ion effects on external Mg2+ block of NR1/2D NMDA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10899-910. PMID 17050728 DOI: 10.1523/Jneurosci.3453-06.2006  0.71
2006 Clarke RJ, Johnson JW. NMDA receptor NR2 subunit dependence of the slow component of magnesium unblock. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5825-34. PMID 16723541 DOI: 10.1523/Jneurosci.0577-06.2006  0.719
2006 Johnson JW, Kotermanski SE. Mechanism of action of memantine. Current Opinion in Pharmacology. 6: 61-7. PMID 16368266 DOI: 10.1016/J.Coph.2005.09.007  0.849
2005 Blanpied TA, Clarke RJ, Johnson JW. Amantadine inhibits NMDA receptors by accelerating channel closure during channel block. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3312-22. PMID 15800186 DOI: 10.1523/Jneurosci.4262-04.2005  0.815
2005 Qian A, Buller AL, Johnson JW. NR2 subunit-dependence of NMDA receptor channel block by external Mg2+. The Journal of Physiology. 562: 319-31. PMID 15513936 DOI: 10.1113/Jphysiol.2004.076737  0.723
2003 Johnson JW. Acid tests of N-methyl-D-aspartate receptor gating basics. Molecular Pharmacology. 63: 1199-201. PMID 12761326 DOI: 10.1124/mol.63.6.1199  0.475
2002 Qian A, Johnson JW. Channel gating of NMDA receptors. Physiology & Behavior. 77: 577-82. PMID 12527002 DOI: 10.1016/S0031-9384(02)00906-X  0.745
2002 Qian A, Antonov SM, Johnson JW. Modulation by permeant ions of Mg(2+) inhibition of NMDA-activated whole-cell currents in rat cortical neurons. The Journal of Physiology. 538: 65-77. PMID 11773317 DOI: 10.1113/Jphysiol.2001.012685  0.768
2002 Johnson JW, Qian A. Interaction between channel blockers and channel gating of NMDA receptors Biologicheskie Membrany. 19: 17-22.  0.429
2001 Li-Smerin Y, Levitan ES, Johnson JW. Free intracellular Mg(2+) concentration and inhibition of NMDA responses in cultured rat neurons. The Journal of Physiology. 533: 729-43. PMID 11410630 DOI: 10.1111/j.1469-7793.2001.t01-1-00729.x  0.461
2000 Stanciu M, Wang Y, Kentor R, Burke N, Watkins S, Kress G, Reynolds I, Klann E, Angiolieri MR, Johnson JW, DeFranco DB. Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures. The Journal of Biological Chemistry. 275: 12200-6. PMID 10766856 DOI: 10.1074/Jbc.275.16.12200  0.347
2000 Li-Smerin Y, Aizenman E, Johnson JW. Inhibition by intracellular Mg(2+) of recombinant N-methyl-D-aspartate receptors expressed in Chinese hamster ovary cells. The Journal of Pharmacology and Experimental Therapeutics. 292: 1104-10. PMID 10688629  0.473
1999 Antonov SM, Johnson JW. Permeant ion regulation of N-methyl-D-aspartate receptor channel block by Mg(2+). Proceedings of the National Academy of Sciences of the United States of America. 96: 14571-6. PMID 10588746 DOI: 10.1073/Pnas.96.25.14571  0.779
1998 Antonov SM, Gmiro VE, Johnson JW. Binding sites for permeant ions in the channel of NMDA receptors and their effects on channel block. Nature Neuroscience. 1: 451-61. PMID 10196542 DOI: 10.1038/2167  0.75
1998 Dilmore JG, Johnson JW. Open channel block and alteration of N-methyl-D-aspartic acid receptor gating by an analog of phencyclidine. Biophysical Journal. 75: 1801-16. PMID 9746522 DOI: 10.1016/S0006-3495(98)77622-2  0.539
1997 Blanpied TA, Boeckman FA, Aizenman E, Johnson JW. Trapping channel block of NMDA-activated responses by amantadine and memantine. Journal of Neurophysiology. 77: 309-23. PMID 9120573 DOI: 10.1152/Jn.1997.77.1.309  0.639
1996 Li-Smerin Y, Johnson JW. Effects of intracellular Mg2+ on channel gating and steady-state responses of the NMDA receptor in cultured rat neurons. The Journal of Physiology. 491: 137-50. PMID 9011606 DOI: 10.1113/Jphysiol.1996.Sp021202  0.508
1996 Li-Smerin Y, Johnson JW. Kinetics of the block by intracellular Mg2+ of the NMDA-activated channel in cultured rat neurons. The Journal of Physiology. 491: 121-35. PMID 9011604 DOI: 10.1113/Jphysiol.1996.Sp021201  0.463
1996 Magazanik LG, Antonov SM, Lukomskaya NYa, Potap'eva NN, Gmiro VE, Johnson J. Blockade of glutamate- and cholinergic ion channels by amantadane derivatives. Neuroscience and Behavioral Physiology. 26: 13-22. PMID 8801464 DOI: 10.1007/Bf02391151  0.735
1996 Antonov SM, Johnson JW. Voltage-dependent interaction of open-channel blocking molecules with gating of NMDA receptors in rat cortical neurons. The Journal of Physiology. 493: 425-45. PMID 8782107 DOI: 10.1113/Jphysiol.1996.Sp021394  0.744
1995 Langdon RB, Johnson JW, Barrionuevo G. Posttetanic potentiation and presynaptically induced long-term potentiation at the mossy fiber synapse in rat hippocampus. Journal of Neurobiology. 26: 370-85. PMID 7775970 DOI: 10.1002/neu.480260309  0.35
1992 Johnson JW, Ascher P. Equilibrium and kinetic study of glycine action on the N-methyl-D-aspartate receptor in cultured mouse brain neurons. The Journal of Physiology. 455: 339-65. PMID 1484357 DOI: 10.1113/Jphysiol.1992.Sp019305  0.667
1990 Sather W, Johnson JW, Henderson G, Ascher P. Glycine-insensitive desensitization of NMDA responses in cultured mouse embryonic neurons. Neuron. 4: 725-31. PMID 2160836 DOI: 10.1016/0896-6273(90)90198-O  0.768
1990 Henderson G, Johnson JW, Ascher P. Competitive antagonists and partial agonists at the glycine modulatory site of the mouse N-methyl-D-aspartate receptor. The Journal of Physiology. 430: 189-212. PMID 1707965 DOI: 10.1113/Jphysiol.1990.Sp018288  0.589
1990 Johnson JW, Ascher P. Voltage-dependent block by intracellular Mg2+ of N-methyl-D-aspartate-activated channels. Biophysical Journal. 57: 1085-90. PMID 1692749 DOI: 10.1016/S0006-3495(90)82626-6  0.623
1989 Johnson JW, Thompson S. Measurement of nonuniform current densities and current kinetics in Aplysia neurons using a large patch method. Biophysical Journal. 55: 299-308. PMID 2713443 DOI: 10.1016/S0006-3495(89)82805-X  0.55
1988 Llano I, Marty A, Johnson JW, Ascher P, Gähwiler BH. Patch-clamp recording of amino acid-activated responses in "organotypic" slice cultures. Proceedings of the National Academy of Sciences of the United States of America. 85: 3221-5. PMID 2834737 DOI: 10.1073/Pnas.85.9.3221  0.786
1987 Johnson JW, Ascher P. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature. 325: 529-31. PMID 2433595 DOI: 10.1038/325529a0  0.691
1986 Thompson S, Smith SJ, Johnson JW. Slow outward tail currents in molluscan bursting pacemaker neurons: two components differing in temperature sensitivity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 3169-76. PMID 3772428  0.536
1986 Ruben P, Johnson JW, Thompson S. Analysis of FMRF-amide effects on Aplysia bursting neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 252-9. PMID 2418174 DOI: 10.1523/Jneurosci.06-01-00252.1986  0.557
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