Year |
Citation |
Score |
2024 |
Lu F, Yang P, Zhang D, Wang X, Cheng H. Thirty years of Ca spark research: digital principle of cell signaling unveiled. Biophysics Reports. 10: 259-265. PMID 39539284 DOI: 10.52601/bpr.2024.240031 |
0.358 |
|
2021 |
Lu F, Li Y, Lin S, Cheng H, Yang S. Spatiotemporal regulation of store-operated calcium entry in cancer metastasis. Biochemical Society Transactions. PMID 34854917 DOI: 10.1042/BST20210307 |
0.307 |
|
2020 |
Lu F, Zhao Y, Xie W, Guo Q, Wang SQ, Wang X, Cheng H. Imaging Sarcoplasmic Reticulum Ca Signaling in Intact Cardiac Myocytes. Circulation. 142: 1503-1505. PMID 33044861 DOI: 10.1161/CIRCULATIONAHA.120.047784 |
0.352 |
|
2020 |
Wu D, Jian C, Peng Q, Hou T, Wu K, Shang B, Zhao M, Wang Y, Zheng W, Ma Q, Li CY, Cheng H, Wang X, Zhao L. Prohibitin 2 deficiency impairs cardiac fatty acid oxidation and causes heart failure. Cell Death & Disease. 11: 181. PMID 32165613 DOI: 10.1038/S41419-020-2374-7 |
0.314 |
|
2019 |
Lin Y, Li LL, Nie W, Liu X, Adler A, Xiao C, Lu F, Wang L, Han H, Wang X, Gan WB, Cheng H. Brain activity regulates loose coupling between mitochondrial and cytosolic Ca transients. Nature Communications. 10: 5277. PMID 31754099 DOI: 10.1038/S41467-019-13142-0 |
0.68 |
|
2019 |
Hou T, Zhang R, Jian C, Ding W, Wang Y, Ling S, Ma Q, Hu X, Cheng H, Wang X. NDUFAB1 confers cardio-protection by enhancing mitochondrial bioenergetics through coordination of respiratory complex and supercomplex assembly. Cell Research. PMID 31366990 DOI: 10.1038/S41422-019-0208-X |
0.336 |
|
2019 |
Sun C, Shui B, Zhao W, Liu H, Li W, Lee JC, Doran R, Lee FK, Sun T, Shen QS, Wang X, Reining S, Kotlikoff MI, Zhang Z, Cheng H. Central role of IPR2-mediated Ca oscillation in self-renewal of liver cancer stem cells elucidated by high-signal ER sensor. Cell Death & Disease. 10: 396. PMID 31113961 DOI: 10.1038/S41419-019-1613-2 |
0.443 |
|
2019 |
Li S, Keung W, Cheng H, Li RA. Structural and Mechanistic Bases of Nuclear Calcium Signaling in Human Pluripotent Stem Cell-Derived Ventricular Cardiomyocytes. Stem Cells International. 2019: 8765752. PMID 31065282 DOI: 10.1155/2019/8765752 |
0.394 |
|
2019 |
Lu F, Sun J, Zheng Q, Li J, Hu Y, Yu P, He H, Zhao Y, Wang X, Yang S, Cheng H. Imaging elemental events of store-operated Ca entry in invading cancer cells with plasmalemmal targeted sensors. Journal of Cell Science. PMID 30814332 DOI: 10.1242/Jcs.224923 |
0.487 |
|
2018 |
Zhao Q, Lu D, Wang J, Liu B, Cheng H, Mattson MP, Cheng A. Calcium dysregulation mediates mitochondrial and neurite outgrowth abnormalities in SOD2 deficient embryonic cerebral cortical neurons. Cell Death and Differentiation. PMID 30390091 DOI: 10.1038/S41418-018-0230-4 |
0.393 |
|
2018 |
Ye J, Zheng Q, Jia S, Qiao X, Cao Y, Xu C, Weng L, Zhao L, Chen Y, Liu J, Wang T, Cheng H, Zheng M. Programmed Cell Death 5 Provides Negative Feedback on Cardiac Hypertrophy Through the Stabilization of Sarco/Endoplasmic Reticulum Ca-ATPase 2a Protein. Hypertension (Dallas, Tex. : 1979). 72: 889-901. PMID 30354711 DOI: 10.1161/Hypertensionaha.118.11357 |
0.414 |
|
2018 |
Lu F, Sun J, Sun T, Cheng H, Yang S. Fluorescence-Based Measurements of Store-Operated Ca Entry in Cancer Cells Using Fluo-4 and Confocal Live-Cell Imaging. Methods in Molecular Biology (Clifton, N.J.). 1843: 63-68. PMID 30203277 DOI: 10.1007/978-1-4939-8704-7_5 |
0.309 |
|
2017 |
Wang X, Zhang X, Wu D, Huang Z, Hou T, Jian C, Yu P, Lu F, Zhang R, Sun T, Li J, Qi W, Wang Y, Gao F, Cheng H. Mitochondrial flashes regulate ATP homeostasis in the heart. Elife. 6. PMID 28692422 DOI: 10.7554/Elife.23908 |
0.336 |
|
2017 |
Fu ZX, Tan X, Fang H, Lau PM, Wang X, Cheng H, Bi GQ. Dendritic mitoflash as a putative signal for stabilizing long-term synaptic plasticity. Nature Communications. 8: 31. PMID 28652625 DOI: 10.1038/S41467-017-00043-3 |
0.307 |
|
2017 |
Jian C, Xu F, Hou T, Sun T, Jinghang L, Cheng H, Wang X. Deficiency of PHB complex impairs respiratory supercomplex formation and activates mitochondrial flashes. Journal of Cell Science. PMID 28630166 DOI: 10.1242/Jcs.198523 |
0.332 |
|
2017 |
Karam C, Yi J, Xiao Y, Dhakal K, Zhang L, Li X, Manno C, Xu J, Li K, Cheng H, Ma J, Zhou J. Absence of physiological Ca(2+) transients is an initial trigger for mitochondrial dysfunction in skeletal muscle following denervation. Skeletal Muscle. 7: 6. PMID 28395670 DOI: 10.1186/S13395-017-0123-0 |
0.361 |
|
2017 |
Feng G, Liu B, Hou T, Wang X, Cheng H. Mitochondrial Flashes: Elemental Signaling Events in Eukaryotic Cells. Handbook of Experimental Pharmacology. PMID 28233181 DOI: 10.1007/164_2016_129 |
0.374 |
|
2017 |
Wang X, Zhang X, Wu D, Huang Z, Hou T, Jian C, Yu P, Lu F, Zhang R, Sun T, Li J, Qi W, Wang Y, Gao F, Cheng H. Author response: Mitochondrial flashes regulate ATP homeostasis in the heart Elife. DOI: 10.7554/Elife.23908.024 |
0.332 |
|
2017 |
Li J, Xie W, Chen X, Huo Y, Cheng H, Tan W. A novel stochastic reaction-diffusion model of Ca 2+ blink in cardiac myocytes Science Bulletin. 62: 5-8. DOI: 10.1016/J.Scib.2016.12.001 |
0.397 |
|
2016 |
Li W, Sun T, Liu B, Wu D, Qi W, Wang X, Ma Q, Cheng H. Regulation of Mitoflash Biogenesis and Signaling by Mitochondrial Dynamics. Scientific Reports. 6: 32933. PMID 27623243 DOI: 10.1038/Srep32933 |
0.306 |
|
2016 |
Wang X, Zhang X, Huang Z, Wu D, Liu B, Zhang R, Yin R, Hou T, Jian C, Xu J, Zhao Y, Wang Y, Gao F, Cheng H. Protons Trigger Mitochondrial Flashes. Biophysical Journal. 111: 386-394. PMID 27463140 DOI: 10.1016/J.Bpj.2016.05.052 |
0.337 |
|
2016 |
Wang W, Zhang H, Cheng H. Mitochondrial flashes: from indicator characterization to in vivo imaging. Methods (San Diego, Calif.). PMID 27288722 DOI: 10.1016/J.Ymeth.2016.06.004 |
0.352 |
|
2016 |
Wang W, Gong G, Wang X, Wei-LaPierre L, Cheng H, Dirksen RT, Sheu SS. Mitochondrial Flash: Integrative ROS and pH Signals in Cell and Organelle Biology. Antioxidants & Redox Signaling. PMID 27245241 DOI: 10.1089/Ars.2016.6739 |
0.324 |
|
2016 |
Hou T, Jian C, Xu J, Huang AY, Xi J, Hu K, Wei L, Cheng H, Wang X. Identification of EFHD1 as a novel Ca(2+) sensor for mitoflash activation. Cell Calcium. PMID 26975899 DOI: 10.1016/J.Ceca.2016.03.002 |
0.482 |
|
2016 |
Karam C, Yi J, Manno C, Cheng H, Ma J, Zhou J. Absence of Physiological Calcium Transients Triggers Mitochondrial ROS Production in Skeletal Muscle Following Denervation Biophysical Journal. 110: 311a. DOI: 10.1016/J.Bpj.2015.11.1669 |
0.42 |
|
2015 |
Shang W, Gao H, Lu F, Ma Q, Fang H, Sun T, Xu J, Ding Y, Lin Y, Wang Y, Wang X, Cheng H, Zheng M. Cyclophilin D regulates mitochondrial flashes and metabolism in cardiac myocytes. Journal of Molecular and Cellular Cardiology. PMID 26746144 DOI: 10.1016/J.Yjmcc.2015.10.036 |
0.452 |
|
2015 |
Zhang M, Sun T, Jian C, Lei L, Han P, Lv Q, Yang R, Zhou X, Xu J, Hu Y, Men Y, Huang Y, Zhang C, Zhu X, Wang X, ... Cheng H, et al. Remodeling of Mitochondrial Flashes in Muscular Development and Dystrophy in Zebrafish. Plos One. 10: e0132567. PMID 26186000 DOI: 10.1371/Journal.Pone.0132567 |
0.326 |
|
2015 |
Ding Y, Fang H, Shang W, Xiao Y, Sun T, Hou N, Pan L, Sun X, Ma Q, Zhou J, Wang X, Zhang X, Cheng H. Mitoflash altered by metabolic stress in insulin-resistant skeletal muscle. Journal of Molecular Medicine (Berlin, Germany). PMID 25908643 DOI: 10.1007/S00109-015-1278-Y |
0.323 |
|
2015 |
Zong W, Zhao J, Chen X, Lin Y, Ren H, Zhang Y, Fan M, Zhou Z, Cheng H, Sun Y, Chen L. Large-field high-resolution two-photon digital scanned light-sheet microscopy. Cell Research. 25: 254-7. PMID 25257466 DOI: 10.1038/Cr.2014.124 |
0.347 |
|
2015 |
Brochet DX, Wang G, Lederer WJ, Cheng H. Calcium Signaling among RyR2s within a Calcium Release Unit during a Calcium Spark Biophysical Journal. 108: 568a. DOI: 10.1016/J.Bpj.2014.11.3108 |
0.502 |
|
2014 |
Sun J, Lu F, He H, Shen J, Messina J, Mathew R, Wang D, Sarnaik AA, Chang WC, Kim M, Cheng H, Yang S. STIM1- and Orai1-mediated Ca(2+) oscillation orchestrates invadopodium formation and melanoma invasion. The Journal of Cell Biology. 207: 535-48. PMID 25404747 DOI: 10.1083/Jcb.201407082 |
0.418 |
|
2014 |
Han P, Zhou XH, Chang N, Xiao CL, Yan S, Ren H, Yang XZ, Zhang ML, Wu Q, Tang B, Diao JP, Zhu X, Zhang C, Li CY, Cheng H, et al. Hydrogen peroxide primes heart regeneration with a derepression mechanism. Cell Research. 24: 1091-107. PMID 25124925 DOI: 10.1038/Cr.2014.108 |
0.316 |
|
2014 |
Hou T, Wang X, Ma Q, Cheng H. Mitochondrial flashes: new insights into mitochondrial ROS signalling and beyond. The Journal of Physiology. 592: 3703-13. PMID 25038239 DOI: 10.1113/Jphysiol.2014.275735 |
0.343 |
|
2014 |
Zhang W, Li K, Zhu X, Wu D, Shang W, Yuan X, Huang Z, Zheng M, Wang X, Yang D, Liu J, Cheng H. Subsarcolemmal mitochondrial flashes induced by hypochlorite stimulation in cardiac myocytes. Free Radical Research. 48: 1085-94. PMID 24912881 DOI: 10.3109/10715762.2014.932114 |
0.448 |
|
2014 |
Yan W, Zhang F, Zhang R, Zhang X, Wang Y, Zhou F, Xia Y, Liu P, Gao C, Wang H, Zhang L, Zhou J, Gao F, Gao E, Koch WJ, ... ... Cheng H, et al. Adiponectin regulates SR Ca(2+) cycling following ischemia/reperfusion via sphingosine 1-phosphate-CaMKII signaling in mice. Journal of Molecular and Cellular Cardiology. 74: 183-92. PMID 24852843 DOI: 10.1016/J.Yjmcc.2014.05.010 |
0.468 |
|
2014 |
Jian C, Hou T, Yin R, Cheng H, Wang X. Regulation of superoxide flashes by transient and steady mitochondrial calcium elevations. Science China. Life Sciences. 57: 495-501. PMID 24699914 DOI: 10.1007/S11427-014-4628-Z |
0.354 |
|
2014 |
Shen EZ, Song CQ, Lin Y, Zhang WH, Su PF, Liu WY, Zhang P, Xu J, Lin N, Zhan C, Wang X, Shyr Y, Cheng H, Dong MQ. Mitoflash frequency in early adulthood predicts lifespan in Caenorhabditis elegans. Nature. 508: 128-32. PMID 24522532 DOI: 10.1038/Nature13012 |
0.396 |
|
2014 |
Hou Y, Ghosh P, Wan R, Ouyang X, Cheng H, Mattson MP, Cheng A. Permeability transition pore-mediated mitochondrial superoxide flashes mediate an early inhibitory effect of amyloid beta1-42 on neural progenitor cell proliferation. Neurobiology of Aging. 35: 975-89. PMID 24325797 DOI: 10.1016/J.Neurobiolaging.2013.11.002 |
0.338 |
|
2014 |
Shang W, Lu F, Sun T, Xu J, Li LL, Wang Y, Wang G, Chen L, Wang X, Cannell MB, Wang SQ, Cheng H. Imaging Ca2+ nanosparks in heart with a new targeted biosensor. Circulation Research. 114: 412-20. PMID 24257462 DOI: 10.1161/Circresaha.114.302938 |
0.489 |
|
2014 |
Li S, Cheng H, Tomaselli GF, Li RA. Mechanistic basis of excitation-contraction coupling in human pluripotent stem cell-derived ventricular cardiomyocytes revealed by Ca2+ spark characteristics: direct evidence of functional Ca2+-induced Ca2+ release. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 11: 133-40. PMID 24096168 DOI: 10.1016/j.hrthm.2013.10.006 |
0.365 |
|
2014 |
Zong W, Zhao J, Chen X, Lin Y, Ren H, Zhang Y, Fan M, Zhou Z, Cheng H, Sun Y, Chen L. Two-photon three-axis digital scanned light-sheet microscopy (2P3A-DSLM) Proceedings of Spie. 9198. DOI: 10.1117/12.2062690 |
0.369 |
|
2014 |
Shang W, Lu F, Sun T, Xu J, Li L, Wang Y, Chen L, Wang X, Cannell MB, Wang S, Cheng H. Ca2+ Nanosparks: Junctional Ca2+ Dynamics Probed with a New Targeted Biosensor Biophysical Journal. 106: 319a-320a. DOI: 10.1016/J.Bpj.2013.11.1845 |
0.498 |
|
2014 |
Cheng H, Wang X, Ma Q, Wang W. Origin and Mechanism of Mitochondrial Flashes Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.1286 |
0.355 |
|
2013 |
Zhang H, Shang W, Zhang X, Gu J, Wang X, Zheng M, Wang Y, Zhou Z, Cao JM, Ji G, Zhang R, Cheng H. Β-adrenergic-stimulated L-type channel Ca²+ entry mediates hypoxic Ca²+ overload in intact heart. Journal of Molecular and Cellular Cardiology. 65: 51-8. PMID 24041537 DOI: 10.1016/J.Yjmcc.2013.09.002 |
0.508 |
|
2013 |
Wang X, Fang H, Huang Z, Shang W, Hou T, Cheng A, Cheng H. Imaging ROS signaling in cells and animals. Journal of Molecular Medicine (Berlin, Germany). 91: 917-27. PMID 23873151 DOI: 10.1007/S00109-013-1067-4 |
0.321 |
|
2013 |
Cao Y, Zhang X, Shang W, Xu J, Wang X, Hu X, Ao Y, Cheng H. Proinflammatory Cytokines Stimulate Mitochondrial Superoxide Flashes in Articular Chondrocytes In Vitro and In Situ. Plos One. 8: e66444. PMID 23840469 DOI: 10.1371/Journal.Pone.0066444 |
0.31 |
|
2013 |
Zhang X, Huang Z, Hou T, Xu J, Wang Y, Shang W, Ye T, Cheng H, Gao F, Wang X. Superoxide constitutes a major signal of mitochondrial superoxide flash. Life Sciences. 93: 178-86. PMID 23800644 DOI: 10.1016/J.Lfs.2013.06.012 |
0.323 |
|
2013 |
Sipido KR, Cheng H. T-tubules and ryanodine receptor microdomains: on the road to translation. Cardiovascular Research. 98: 159-61. PMID 23554456 DOI: 10.1093/Cvr/Cvt077 |
0.457 |
|
2013 |
Wei-LaPierre L, Gong G, Gerstner BJ, Ducreux S, Yule DI, Pouvreau S, Wang X, Sheu SS, Cheng H, Dirksen RT, Wang W. Respective contribution of mitochondrial superoxide and pH to mitochondria-targeted circularly permuted yellow fluorescent protein (mt-cpYFP) flash activity. The Journal of Biological Chemistry. 288: 10567-77. PMID 23457298 DOI: 10.1074/Jbc.M113.455709 |
0.312 |
|
2013 |
Zhang H, Gomez AM, Wang X, Yan Y, Zheng M, Cheng H. ROS regulation of microdomain Ca(2+) signalling at the dyads. Cardiovascular Research. 98: 248-58. PMID 23455546 DOI: 10.1093/Cvr/Cvt050 |
0.472 |
|
2013 |
Liu Y, Cheng H, Zhou Y, Zhu Y, Bian R, Chen Y, Li C, Ma Q, Zheng Q, Zhang Y, Jin H, Wang X, Chen Q, Zhu D. Myostatin induces mitochondrial metabolic alteration and typical apoptosis in cancer cells. Cell Death & Disease. 4: e494. PMID 23412387 DOI: 10.1038/Cddis.2013.31 |
0.311 |
|
2013 |
Huang X, Sun L, Ji S, Zhao T, Zhang W, Xu J, Zhang J, Wang Y, Wang X, Franzini-Armstrong C, Zheng M, Cheng H. Kissing and nanotunneling mediate intermitochondrial communication in the heart. Proceedings of the National Academy of Sciences of the United States of America. 110: 2846-51. PMID 23386722 DOI: 10.1073/Pnas.1300741110 |
0.331 |
|
2013 |
Pereira L, Cheng H, Lao DH, Na L, van Oort RJ, Brown JH, Wehrens XH, Chen J, Bers DM. Epac2 mediates cardiac β1-adrenergic-dependent sarcoplasmic reticulum Ca2+ leak and arrhythmia. Circulation. 127: 913-22. PMID 23363625 DOI: 10.1161/Circulationaha.12.148619 |
0.472 |
|
2013 |
Hou T, Zhang X, Xu J, Jian C, Huang Z, Ye T, Hu K, Zheng M, Gao F, Wang X, Cheng H. Synergistic triggering of superoxide flashes by mitochondrial Ca2+ uniport and basal reactive oxygen species elevation. The Journal of Biological Chemistry. 288: 4602-12. PMID 23283965 DOI: 10.1074/Jbc.M112.398297 |
0.477 |
|
2012 |
Hou Y, Ouyang X, Wan R, Cheng H, Mattson MP, Cheng A. Mitochondrial superoxide production negatively regulates neural progenitor proliferation and cerebral cortical development. Stem Cells (Dayton, Ohio). 30: 2535-47. PMID 22949407 DOI: 10.1002/Stem.1213 |
0.33 |
|
2012 |
Zhao T, Huang X, Han L, Wang X, Cheng H, Zhao Y, Chen Q, Chen J, Cheng H, Xiao R, Zheng M. Central role of mitofusin 2 in autophagosome-lysosome fusion in cardiomyocytes. The Journal of Biological Chemistry. 287: 23615-25. PMID 22619176 DOI: 10.1074/Jbc.M112.379164 |
0.359 |
|
2012 |
Brochet DX, Yang D, Cheng H, Lederer WJ. Elementary calcium release events from the sarcoplasmic reticulum in the heart. Advances in Experimental Medicine and Biology. 740: 499-509. PMID 22453956 DOI: 10.1007/978-94-007-2888-2_21 |
0.486 |
|
2012 |
Wang X, Jian C, Zhang X, Huang Z, Xu J, Hou T, Shang W, Ding Y, Zhang W, Ouyang M, Wang Y, Yang Z, Zheng M, Cheng H. Superoxide flashes: elemental events of mitochondrial ROS signaling in the heart. Journal of Molecular and Cellular Cardiology. 52: 940-8. PMID 22405973 DOI: 10.1016/J.Yjmcc.2012.02.007 |
0.375 |
|
2012 |
Li K, Zhang W, Fang H, Xie W, Liu J, Zheng M, Wang X, Wang W, Tan W, Cheng H. Superoxide flashes reveal novel properties of mitochondrial reactive oxygen species excitability in cardiomyocytes. Biophysical Journal. 102: 1011-21. PMID 22404923 DOI: 10.1016/J.Bpj.2012.01.044 |
0.338 |
|
2011 |
Zhou Q, Xiao J, Jiang D, Wang R, Vembaiyan K, Wang A, Smith CD, Xie C, Chen W, Zhang J, Tian X, Jones PP, Zhong X, Guo A, Chen H, ... ... Cheng H, et al. Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release. Nature Medicine. 17: 1003-9. PMID 21743453 DOI: 10.1038/Nm.2406 |
0.381 |
|
2011 |
Han P, Cai W, Wang Y, Lam CK, Arvanitis DA, Singh VP, Chen S, Zhang H, Zhang R, Cheng H, Kranias EG. Catecholaminergic-induced arrhythmias in failing cardiomyocytes associated with human HRCS96A variant overexpression. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1588-95. PMID 21742996 DOI: 10.1152/Ajpheart.01153.2010 |
0.473 |
|
2011 |
Ma Q, Fang H, Shang W, Liu L, Xu Z, Ye T, Wang X, Zheng M, Chen Q, Cheng H. Superoxide flashes: early mitochondrial signals for oxidative stress-induced apoptosis. The Journal of Biological Chemistry. 286: 27573-81. PMID 21659534 DOI: 10.1074/Jbc.M111.241794 |
0.341 |
|
2011 |
Fang H, Chen M, Ding Y, Shang W, Xu J, Zhang X, Zhang W, Li K, Xiao Y, Gao F, Shang S, Li JC, Tian XL, Wang SQ, Zhou J, ... ... Cheng H, et al. Imaging superoxide flash and metabolism-coupled mitochondrial permeability transition in living animals. Cell Research. 21: 1295-304. PMID 21556035 DOI: 10.1038/Cr.2011.81 |
0.348 |
|
2011 |
Lin N, Badie N, Yu L, Abraham D, Cheng H, Bursac N, Rockman HA, Wolf MJ. A method to measure myocardial calcium handling in adult Drosophila. Circulation Research. 108: 1306-15. PMID 21493892 DOI: 10.1161/Circresaha.110.238105 |
0.501 |
|
2011 |
Brochet DX, Xie W, Yang D, Cheng H, Lederer WJ. Quarky calcium release in the heart. Circulation Research. 108: 210-8. PMID 21148431 DOI: 10.1161/Circresaha.110.231258 |
0.481 |
|
2011 |
Brochet DX, Yang D, Cheng H, Lederer WJ. Small Ca2+ Release Events in Rabbit Ventricular Myocytes Biophysical Journal. 100: 352a-353a. DOI: 10.1016/J.Bpj.2010.12.2121 |
0.493 |
|
2011 |
Li K, Fu C, Cheng H, Tan W. Anomalous Subdiffusion of Calcium Spark in Cardiac Myocytes Cellular and Molecular Bioengineering. 4: 457-465. DOI: 10.1007/S12195-011-0174-Y |
0.47 |
|
2010 |
Xie W, Brochet DX, Wei S, Wang X, Cheng H. Deciphering ryanodine receptor array operation in cardiac myocytes. The Journal of General Physiology. 136: 129-33. PMID 20660655 DOI: 10.1085/Jgp.201010416 |
0.334 |
|
2010 |
Lu L, Xia L, Ye X, Cheng H. Simulation of the effect of rogue ryanodine receptors on a calcium wave in ventricular myocytes with heart failure. Physical Biology. 7: 026005. PMID 20505230 DOI: 10.1088/1478-3975/7/2/026005 |
0.452 |
|
2010 |
Wang G, Zhu X, Xie W, Han P, Li K, Sun Z, Wang Y, Chen C, Song R, Cao C, Zhang J, Wu C, Liu J, Cheng H. Rad as a novel regulator of excitation-contraction coupling and beta-adrenergic signaling in heart. Circulation Research. 106: 317-27. PMID 19926875 DOI: 10.1161/Circresaha.109.208272 |
0.427 |
|
2010 |
Peng W, Zhang Y, Zheng M, Cheng H, Zhu W, Cao CM, Xiao RP. Cardioprotection by CaMKII-deltaB is mediated by phosphorylation of heat shock factor 1 and subsequent expression of inducible heat shock protein 70. Circulation Research. 106: 102-10. PMID 19910575 DOI: 10.1161/Circresaha.109.210914 |
0.408 |
|
2009 |
Zhou P, Zhao YT, Guo YB, Xu SM, Bai SH, Lakatta EG, Cheng H, Hao XM, Wang SQ. Beta-adrenergic signaling accelerates and synchronizes cardiac ryanodine receptor response to a single L-type Ca2+ channel. Proceedings of the National Academy of Sciences of the United States of America. 106: 18028-33. PMID 19815510 DOI: 10.1073/Pnas.0906560106 |
0.509 |
|
2009 |
Wei C, Wang X, Chen M, Ouyang K, Song LS, Cheng H. Calcium flickers steer cell migration. Nature. 457: 901-5. PMID 19118385 DOI: 10.1038/nature07577 |
0.329 |
|
2009 |
Li K, Zhang W, Liu J, Wang W, Xie W, Fang H, Wang Y, Zheng M, Tan W, Cheng H. Flash Sniper: Automated Detection and Analysis of Mitochondrial Superoxide Flash Biophysical Journal. 96: 531a-532a. DOI: 10.1016/J.Bpj.2008.12.2743 |
0.324 |
|
2009 |
Fang H, Zhang W, Wang X, Wang W, Li K, Wang Y, Zhang X, Shang S, Tian X, Zhou J, Weisleder N, Ma J, Zheng M, Chen M, Cheng H. In vivo Imaging of Superoxide Flashes in Skeletal Muscle Biophysical Journal. 96: 530a. DOI: 10.1016/J.Bpj.2008.12.2737 |
0.352 |
|
2009 |
Wei S, Chen B, Kutschke W, Weiss R, Lederer W, Anderson M, Cheng H, Song L. Cellular Mechanism of Ca2+−Dependent Arrhythmogenesis in Failing Myocytes of Aortic Banding Rats Biophysical Journal. 96: 513a. DOI: 10.1016/J.Bpj.2008.12.2645 |
0.437 |
|
2009 |
Brochet DX, Yang D, Xie W, Cheng H, Lederer W. Quarky Calcium Sparks in Heart Biophysical Journal. 96: 21a-22a. DOI: 10.1016/J.Bpj.2008.12.1014 |
0.487 |
|
2008 |
Sheu SS, Wang W, Cheng H, Dirksen RT. Superoxide flashes: illuminating new insights into cardiac ischemia/reperfusion injury. Future Cardiology. 4: 551-554. PMID 19649173 DOI: 10.2217/14796678.4.6.551 |
0.38 |
|
2008 |
Cheng H, Lederer WJ. Calcium sparks. Physiological Reviews. 88: 1491-545. PMID 18923188 DOI: 10.1152/physrev.00030.2007 |
0.413 |
|
2008 |
Wang W, Fang H, Groom L, Cheng A, Zhang W, Liu J, Wang X, Li K, Han P, Zheng M, Yin J, Wang W, Mattson MP, Kao JP, Lakatta EG, ... ... Cheng H, et al. Superoxide flashes in single mitochondria. Cell. 134: 279-90. PMID 18662543 DOI: 10.1016/J.Cell.2008.06.017 |
0.332 |
|
2008 |
Yan Y, Liu J, Wei C, Li K, Xie W, Wang Y, Cheng H. Bidirectional regulation of Ca2+ sparks by mitochondria-derived reactive oxygen species in cardiac myocytes. Cardiovascular Research. 77: 432-41. PMID 18006452 DOI: 10.1093/Cvr/Cvm047 |
0.498 |
|
2008 |
Luo D, Yang D, Lan X, Li K, Li X, Chen J, Zhang Y, Xiao RP, Han Q, Cheng H. Nuclear Ca2+ sparks and waves mediated by inositol 1,4,5-trisphosphate receptors in neonatal rat cardiomyocytes. Cell Calcium. 43: 165-74. PMID 17583790 DOI: 10.1016/J.Ceca.2007.04.017 |
0.469 |
|
2007 |
Xiao B, Tian X, Xie W, Jones PP, Cai S, Wang X, Jiang D, Kong H, Zhang L, Chen K, Walsh MP, Cheng H, Chen SR. Functional consequence of protein kinase A-dependent phosphorylation of the cardiac ryanodine receptor: sensitization of store overload-induced Ca2+ release. The Journal of Biological Chemistry. 282: 30256-64. PMID 17693412 DOI: 10.1074/Jbc.M703510200 |
0.489 |
|
2007 |
Zhao G, Zhao Y, Pan B, Liu J, Huang X, Zhang X, Cao C, Hou N, Wu C, Zhao KS, Cheng H. Hypersensitivity of BKCa to Ca2+ sparks underlies hyporeactivity of arterial smooth muscle in shock. Circulation Research. 101: 493-502. PMID 17641230 DOI: 10.1161/Circresaha.107.157271 |
0.474 |
|
2007 |
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Yang D, Zhu WZ, Xiao B, Brochet DX, Chen SR, Lakatta EG, Xiao RP, Cheng H. Ca2+/calmodulin kinase II-dependent phosphorylation of ryanodine receptors suppresses Ca2+ sparks and Ca2+ waves in cardiac myocytes. Circulation Research. 100: 399-407. PMID 17234969 DOI: 10.1161/01.Res.0000258022.13090.55 |
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Song LS, Pi Y, Kim SJ, Yatani A, Guatimosim S, Kudej RK, Zhang Q, Cheng H, Hittinger L, Ghaleh B, Vatner DE, Lederer WJ, Vatner SF. Paradoxical cellular Ca2+ signaling in severe but compensated canine left ventricular hypertrophy. Circulation Research. 97: 457-64. PMID 16051885 DOI: 10.1161/01.Res.0000179722.79295.D4 |
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Zhu WZ, Chakir K, Zhang S, Yang D, Lavoie C, Bouvier M, Hébert TE, Lakatta EG, Cheng H, Xiao RP. Heterodimerization of beta1- and beta2-adrenergic receptor subtypes optimizes beta-adrenergic modulation of cardiac contractility. Circulation Research. 97: 244-51. PMID 16002745 DOI: 10.1161/01.Res.0000176764.38934.86 |
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Wang X, Weisleder N, Collet C, Zhou J, Chu Y, Hirata Y, Zhao X, Pan Z, Brotto M, Cheng H, Ma J. Uncontrolled calcium sparks act as a dystrophic signal for mammalian skeletal muscle. Nature Cell Biology. 7: 525-30. PMID 15834406 DOI: 10.1038/Ncb1254 |
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Xiao B, Jiang MT, Zhao M, Yang D, Sutherland C, Lai FA, Walsh MP, Warltier DC, Cheng H, Chen SR. Characterization of a novel PKA phosphorylation site, serine-2030, reveals no PKA hyperphosphorylation of the cardiac ryanodine receptor in canine heart failure. Circulation Research. 96: 847-55. PMID 15790957 DOI: 10.1161/01.Res.0000163276.26083.E8 |
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Ouyang K, Wu C, Cheng H. Ca(2+)-induced Ca(2+) release in sensory neurons: low gain amplification confers intrinsic stability. The Journal of Biological Chemistry. 280: 15898-902. PMID 15749692 DOI: 10.1074/Jbc.C500026200 |
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Jiang D, Xiao B, Yang D, Wang R, Choi P, Zhang L, Cheng H, Chen SR. RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release (SOICR). Proceedings of the National Academy of Sciences of the United States of America. 101: 13062-7. PMID 15322274 DOI: 10.1073/Pnas.0402388101 |
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Stern MD, Cheng H. Putting out the fire: what terminates calcium-induced calcium release in cardiac muscle? Cell Calcium. 35: 591-601. PMID 15110149 DOI: 10.1016/J.Ceca.2004.01.013 |
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Wang SQ, Stern MD, Ríos E, Cheng H. The quantal nature of Ca2+ sparks and in situ operation of the ryanodine receptor array in cardiac cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 3979-84. PMID 15004280 DOI: 10.1073/Pnas.0306157101 |
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Ding JH, Xu X, Yang D, Chu PH, Dalton ND, Ye Z, Yeakley JM, Cheng H, Xiao RP, Ross J, Chen J, Fu XD. Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart. The Embo Journal. 23: 885-96. PMID 14963485 DOI: 10.1038/Sj.Emboj.7600054 |
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Shen JX, Wang S, Song LS, Han T, Cheng H. Polymorphism of Ca2+ sparks evoked from in-focus Ca2+ release units in cardiac myocytes. Biophysical Journal. 86: 182-90. PMID 14695261 DOI: 10.1016/S0006-3495(04)74095-3 |
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Zhu WZ, Wang SQ, Chakir K, Yang D, Zhang T, Brown JH, Devic E, Kobilka BK, Cheng H, Xiao RP. Linkage of beta1-adrenergic stimulation to apoptotic heart cell death through protein kinase A-independent activation of Ca2+/calmodulin kinase II. The Journal of Clinical Investigation. 111: 617-25. PMID 12618516 DOI: 10.1172/Jci16326 |
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Wang SQ, Lakatta EG, Cheng H, Zhou ZQ. Adaptive mechanisms of intracellular calcium homeostasis in mammalian hibernators. The Journal of Experimental Biology. 205: 2957-62. PMID 12200399 |
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Cheng H, Wang SQ. Calcium signaling between sarcolemmal calcium channels and ryanodine receptors in heart cells. Frontiers in Bioscience : a Journal and Virtual Library. 7: d1867-78. PMID 12161336 DOI: 10.2741/Cheng |
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Wang SQ, Song LS, Xu L, Meissner G, Lakatta EG, RÃos E, Stern MD, Cheng H. Thermodynamically irreversible gating of ryanodine receptors in situ revealed by stereotyped duration of release in Ca(2+) sparks. Biophysical Journal. 83: 242-51. PMID 12080116 DOI: 10.1016/S0006-3495(02)75165-5 |
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Pan Z, Yang D, Nagaraj RY, Nosek TA, Nishi M, Takeshima H, Cheng H, Ma J. Dysfunction of store-operated calcium channel in muscle cells lacking mg29 Nature Cell Biology. 4: 379-383. PMID 11988740 DOI: 10.1038/Ncb788 |
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Song LS, Guia A, Muth JN, Rubio M, Wang SQ, Xiao RP, Josephson IR, Lakatta EG, Schwartz A, Cheng H. Ca(2+) signaling in cardiac myocytes overexpressing the alpha(1) subunit of L-type Ca(2+) channel. Circulation Research. 90: 174-81. PMID 11834710 DOI: 10.1161/Hh0202.103230 |
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Haak LL, Song LS, Molinski TF, Pessah IN, Cheng H, Russell JT. Sparks and puffs in oligodendrocyte progenitors: cross talk between ryanodine receptors and inositol trisphosphate receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 3860-70. PMID 11356874 DOI: 10.1523/Jneurosci.21-11-03860.2001 |
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Song LS, Wang SQ, Xiao RP, Spurgeon H, Lakatta E, Cheng H. β-Adrenergic Stimulation Synchronizes Intracellular Ca2+ Release During Excitation-Contraction Coupling in Cardiac Myocytes Circulation Research. 88: 794-801. PMID 11325871 DOI: 10.1161/Hh0801.090461 |
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Wang S, Song L, Lakatta EG, Cheng H. Ca2+ signalling between single L-type Ca2+ channels and ryanodine receptors in heart cells. Nature. 410: 592-596. PMID 11279498 DOI: 10.1038/35069083 |
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RÃos E, Shirokova N, Kirsch WG, Pizarro G, Stern MD, Cheng H, González A. A preferred amplitude of calcium sparks in skeletal muscle. Biophysical Journal. 80: 169-83. PMID 11159393 DOI: 10.1016/S0006-3495(01)76005-5 |
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Chen-Izu Y, Xiao RP, Izu LT, Cheng H, Kuschel M, Spurgeon H, Lakatta EG. G(i)-dependent localization of beta(2)-adrenergic receptor signaling to L-type Ca(2+) channels. Biophysical Journal. 79: 2547-56. PMID 11053129 DOI: 10.1016/S0006-3495(00)76495-2 |
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Wang S, Lakatta E, Cheng H. Post-spark refractoriness of a single Ca2+-release unit in cardiac myocytes Journal of Molecular and Cellular Cardiology. 33: A128. DOI: 10.1016/S0022-2828(01)90511-5 |
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Song L, Wang S, Iakatta EG, Cheng H. β-Adrenergic stimulation synchronizes intracellular Ca2+ release during E-C coupling in heart cells Journal of Molecular and Cellular Cardiology. 33: A113. DOI: 10.1016/S0022-2828(01)90451-1 |
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Vinogradova TM, Zhou Y, Bogdanov KY, Yang D, Kuschel M, Cheng H, Xiao R. Sinoatrial Node Pacemaker Activity Requires Ca2+/Calmodulin-Dependent Protein Kinase II Activation Circulation Research. 87: 760-767. PMID 11055979 DOI: 10.1161/01.Res.87.9.760 |
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Hagemann D, Kuschel M, Kuramochi T, Zhu W, Cheng H, Xiao R. Frequency-encoding Thr17 Phospholamban Phosphorylation Is Independent of Ser16 Phosphorylation in Cardiac Myocytes Journal of Biological Chemistry. 275: 22532-22536. PMID 10825152 DOI: 10.1074/Jbc.C000253200 |
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Song L, Ren G, Chen Z, Chen Z, Zhou Z, Cheng H. Electrophysiological effects of protopine in cardiac myocytes: inhibition of multiple cation channel currents. British Journal of Pharmacology. 129: 893-900. PMID 10696087 DOI: 10.1038/Sj.Bjp.0703132 |
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Xiao RP, Cheng H, Zhou YY, Kuschel M, Lakatta EG. Recent advances in cardiac beta(2)-adrenergic signal transduction. Circulation Research. 85: 1092-100. PMID 10571541 DOI: 10.1161/01.Res.85.11.1092 |
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Zhou YY, Song LS, Lakatta EG, Xiao RP, Cheng H. Constitutive β2‐adrenergic signalling enhances sarcoplasmic reticulum Ca2+ cycling to augment contraction in mouse heart The Journal of Physiology. 521: 351-361. PMID 10581307 DOI: 10.1111/J.1469-7793.1999.00351.X |
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Zhou YY, Cheng H, Song LS, Wang D, Lakatta E, Xiao RP. Spontaneous β2-Adrenergic Signaling Fails To Modulate L-Type Ca2+ Current in Mouse Ventricular Myocytes Molecular Pharmacology. 56: 485-493. PMID 10462536 DOI: 10.1124/Mol.56.3.485 |
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Stern MD, Song LS, Cheng H, Sham JS, Yang HT, Boheler KR, Ríos E. Local control models of cardiac excitation-contraction coupling. A possible role for allosteric interactions between ryanodine receptors. The Journal of General Physiology. 113: 469-89. PMID 10051521 DOI: 10.1085/Jgp.113.3.469 |
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Xiao RP, Avdonin P, Zhou YY, Cheng H, Akhter SA, Eschenhagen T, Lefkowitz RJ, Koch WJ, Lakatta EG. Coupling of beta2-adrenoceptor to Gi proteins and its physiological relevance in murine cardiac myocytes. Circulation Research. 84: 43-52. PMID 9915773 DOI: 10.1161/01.Res.84.1.43 |
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Song LS, Sham JS, Stern MD, Lakatta EG, Cheng H. Direct measurement of SR release flux by tracking 'Ca2+ spikes' in rat cardiac myocytes. The Journal of Physiology. 512: 677-91. PMID 9769413 DOI: 10.1111/J.1469-7793.1998.677Bd.X |
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Smith GD, Keizer JE, Stern MD, Lederer WJ, Cheng H. A simple numerical model of calcium spark formation and detection in cardiac myocytes. Biophysical Journal. 75: 15-32. PMID 9649364 DOI: 10.1016/S0006-3495(98)77491-0 |
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Song LS, Stern MD, Lakatta EG, Cheng H. Partial depletion of sarcoplasmic reticulum calcium does not prevent calcium sparks in rat ventricular myocytes. The Journal of Physiology. 505: 665-75. PMID 9457644 DOI: 10.1111/J.1469-7793.1997.665Ba.X |
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Zhou YY, Cheng H, Bogdanov KY, Hohl C, Altschuld R, Lakatta EG, Xiao RP. Localized cAMP-dependent signaling mediates beta 2-adrenergic modulation of cardiac excitation-contraction coupling American Journal of Physiology-Heart and Circulatory Physiology. 273. PMID 9321856 DOI: 10.1152/Ajpheart.1997.273.3.H1611 |
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Xiao RP, Valdivia HH, Bogdanov K, Valdivia C, Lakatta EG, Cheng H. The immunophilin FK506-binding protein modulates Ca2+ release channel closure in rat heart. The Journal of Physiology. 500: 343-54. PMID 9147322 DOI: 10.1113/Jphysiol.1997.Sp022025 |
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Gómez AM, Valdivia HH, Cheng H, Lederer MR, Santana LF, Cannell MB, McCune SA, Altschuld RA, Lederer WJ. Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure. Science (New York, N.Y.). 276: 800-6. PMID 9115206 DOI: 10.1126/Science.276.5313.800 |
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Cheng H, Lederer MR, Xiao RP, Gómez AM, Zhou YY, Ziman B, Spurgeon H, Lakatta EG, Lederer WJ. Excitation-contraction coupling in heart: new insights from Ca2+ sparks. Cell Calcium. 20: 129-40. PMID 8889204 DOI: 10.1016/S0143-4160(96)90102-5 |
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Piston DW, Kirby MS, Cheng H, Lederer WJ, Webb WW. Two-photon-excitation fluorescence imaging of three-dimensional calcium-ion activity. Applied Optics. 33: 662-9. PMID 20862061 DOI: 10.1364/Ao.33.000662 |
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Xiao RP, Cheng H, Lederer WJ, Suzuki T, Lakatta EG. Dual regulation of Ca2+/calmodulin-dependent kinase II activity by membrane voltage and by calcium influx. Proceedings of the National Academy of Sciences of the United States of America. 91: 9659-63. PMID 7937825 DOI: 10.1073/Pnas.91.20.9659 |
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