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Hao Wu - Publications

Affiliations: 
Biological Chemistry and Molecular Pharmacology Harvard Medical School, Boston, MA, United States 
Area:
structural immunology
Website:
http://www.fas.harvard.edu/~biophys/Hao_Wu.htm
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Year Citation  Score
2024 Fu J, Schroder K, Wu H. Mechanistic insights from inflammasome structures. Nature Reviews. Immunology. PMID 38374299 DOI: 10.1038/s41577-024-00995-w  0.333
2024 Li R, Zan Y, Wang D, Chen X, Wang A, Tan H, Zhang G, Ding S, Shen C, Wu H, Zhu S. A mouse model to distinguish NLRP6-mediated inflammasome-dependent and -independent functions. Proceedings of the National Academy of Sciences of the United States of America. 121: e2321419121. PMID 38289959 DOI: 10.1073/pnas.2321419121  0.3
2023 Paidimuddala B, Cao J, Nash G, Xie Q, Wu H, Zhang L. Mechanism of NAIP-NLRC4 inflammasome activation revealed by cryo-EM structure of unliganded NAIP5. Nature Structural & Molecular Biology. PMID 36604500 DOI: 10.1038/s41594-022-00889-2  0.318
2022 Fu J, Wu H. Structural Mechanisms of NLRP3 Inflammasome Assembly and Activation. Annual Review of Immunology. PMID 36750315 DOI: 10.1146/annurev-immunol-081022-021207  0.327
2022 Xiao L, Magupalli VG, Wu H. Cryo-EM structures of the active NLRP3 inflammasome disk. Nature. PMID 36442502 DOI: 10.1038/s41586-022-05570-8  0.328
2022 Fontana P, Dong Y, Pi X, Tong AB, Hecksel CW, Wang L, Fu TM, Bustamante C, Wu H. Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold. Science (New York, N.Y.). 376: eabm9326. PMID 35679401 DOI: 10.1126/science.abm9326  0.697
2022 Zheng W, Shen C, Wang L, Rawson S, Xie WJ, Nist-Lund C, Wu J, Shen Z, Xia S, Holt JR, Wu H, Fu TM. pH regulates potassium conductance and drives a constitutive proton current in human TMEM175. Science Advances. 8: eabm1568. PMID 35333573 DOI: 10.1126/sciadv.abm1568  0.642
2022 Xiong X, Tian S, Yang P, Lebreton F, Bao H, Sheng K, Yin L, Chen P, Zhang J, Qi W, Ruan J, Wu H, Chen H, Breault DT, Wu H, et al. Emerging enterococcus pore-forming toxins with MHC/HLA-I as receptors. Cell. PMID 35259335 DOI: 10.1016/j.cell.2022.02.002  0.694
2022 Vora SM, Fontana P, Mao T, Leger V, Zhang Y, Fu TM, Lieberman J, Gehrke L, Shi M, Wang L, Iwasaki A, Wu H. Targeting stem-loop 1 of the SARS-CoV-2 5' UTR to suppress viral translation and Nsp1 evasion. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35149555 DOI: 10.1073/pnas.2117198119  0.677
2021 Shen C, Li R, Negro R, Cheng J, Vora SM, Fu TM, Wang A, He K, Andreeva L, Gao P, Tian Z, Flavell RA, Zhu S, Wu H. Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome. Cell. PMID 34678144 DOI: 10.1016/j.cell.2021.09.032  0.704
2021 Gao W, Li Y, Liu X, Wang S, Mei P, Chen Z, Liu K, Li S, Xu XW, Gan J, Wu J, Ji C, Ding C, Liu X, Lai Y, ... ... Wu H, et al. TRIM21 regulates pyroptotic cell death by promoting Gasdermin D oligomerization. Cell Death and Differentiation. PMID 34511601 DOI: 10.1038/s41418-021-00867-z  0.663
2021 Yang Q, Li J, Zhang Z, Wu X, Liao T, Yu S, You Z, Hou X, Ye J, Liu G, Ma S, Xie G, Zhou Y, Li M, Wu M, ... ... Wu H, ... ... Wu H, et al. Clinical characteristics and a decision tree model to predict death outcome in severe COVID-19 patients. Bmc Infectious Diseases. 21: 783. PMID 34372767 DOI: 10.1186/s12879-021-06478-w  0.559
2021 Zhou Y, Yang Q, Ye J, Wu X, Hou X, Feng Y, Luo B, Li J, Yang G, Li L, Yang X, Wang B, Zhao S, Li L, Li Q, ... ... Wu H, et al. Clinical features and death risk factors in COVID-19 patients with cancer: a retrospective study. Bmc Infectious Diseases. 21: 760. PMID 34353293 DOI: 10.1186/s12879-021-06495-9  0.555
2021 Zhu L, Xie H, Liu Q, Ma F, Wu H. Klotho inhibits H O -induced oxidative stress and apoptosis in periodontal ligament stem cells by regulating UCP2 expression. Clinical and Experimental Pharmacology & Physiology. PMID 34174105 DOI: 10.1111/1440-1681.13547  0.382
2021 Zhu L, Xie H, Liu Q, Ma F, Wu H. Klotho inhibits H O -induced oxidative stress and apoptosis in periodontal ligament stem cells by regulating UCP2 expression. Clinical and Experimental Pharmacology & Physiology. PMID 34174105 DOI: 10.1111/1440-1681.13547  0.382
2021 Wang L, Sharif H, Vora SM, Zheng Y, Wu H. Structures and functions of the inflammasome engine. The Journal of Allergy and Clinical Immunology. 147: 2021-2029. PMID 34092352 DOI: 10.1016/j.jaci.2021.04.018  0.568
2021 Sharif H, Hollingsworth LR, Griswold AR, Hsiao JC, Wang Q, Bachovchin DA, Wu H. Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment. Immunity. PMID 34019797 DOI: 10.1016/j.immuni.2021.04.024  0.582
2021 Xia S, Zhang Z, Magupalli VG, Pablo JL, Dong Y, Vora SM, Wang L, Fu TM, Jacobson MP, Greka A, Lieberman J, Ruan J, Wu H. Gasdermin D pore structure reveals preferential release of mature interleukin-1. Nature. PMID 33883744 DOI: 10.1038/s41586-021-03478-3  0.778
2021 Guo JC, Xie H, Wu H, Tong TJ. [Efficacy of curcumin in the treatment of oral submucous fibrosis: a Meta-analysis]. Hua Xi Kou Qiang Yi Xue Za Zhi = Huaxi Kouqiang Yixue Zazhi = West China Journal of Stomatology. 39: 195-202. PMID 33834675 DOI: 10.7518/hxkq.2021.02.011  0.316
2021 Hollingsworth LR, Sharif H, Griswold AR, Fontana P, Mintseris J, Dagbay KB, Paulo JA, Gygi SP, Bachovchin DA, Wu H. DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation. Nature. PMID 33731932 DOI: 10.1038/s41586-021-03350-4  0.608
2021 Wang L, Chen Z, Wu H, Fu TM. Purification and cryoelectron microscopy structure determination of human V-ATPase. Star Protocols. 2: 100350. PMID 33665630 DOI: 10.1016/j.xpro.2021.100350  0.666
2021 Robert Hollingsworth L, David L, Li Y, Griswold AR, Ruan J, Sharif H, Fontana P, Orth-He EL, Fu TM, Bachovchin DA, Wu H. Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes. Nature Communications. 12: 189. PMID 33420033 DOI: 10.1038/s41467-020-20320-y  0.806
2020 Guo J, Xie H, Wu H, Liang M. Efficacy of Lycopene in the Treatment of Oral Submucous Fibrosis: A Meta-analysis of Randomized Controlled Trials. The Journal of Evidence-Based Dental Practice. 20: 101471. PMID 33303091 DOI: 10.1016/j.jebdp.2020.101471  0.31
2020 Guo J, Xie H, Wu H. Preventive Measures for COVID-19 in Dental Treatments. Disaster Medicine and Public Health Preparedness. 1-13. PMID 33092676 DOI: 10.1017/dmp.2020.409  0.316
2020 Wang L, Wu D, Robinson CV, Wu H, Fu TM. Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly. Molecular Cell. PMID 33065002 DOI: 10.1016/j.molcel.2020.09.029  0.683
2020 Shi M, Wang L, Fontana P, Vora S, Zhang Y, Fu TM, Lieberman J, Wu H. SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism. Biorxiv : the Preprint Server For Biology. PMID 32995777 DOI: 10.1101/2020.09.18.302901  0.674
2020 Magupalli VG, Negro R, Tian Y, Hauenstein AV, Di Caprio G, Skillern W, Deng Q, Orning P, Alam HB, Maliga Z, Sharif H, Hu JJ, Evavold CL, Kagan JC, Schmidt FI, ... ... Wu H, et al. HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation. Science (New York, N.Y.). 369. PMID 32943500 DOI: 10.1126/Science.Aas8995  0.806
2020 Zang Z, Lv Y, Liu S, Yang W, Ci J, Ren X, Wang Z, Wu H, Ma W, Jiang L, Yang W. A Novel ERF Transcription Factor, , Positively Regulates Maize Resistance to . Frontiers in Plant Science. 11: 850. PMID 32612628 DOI: 10.3389/fpls.2020.00850  0.319
2020 Guo J, Xie H, Liang M, Wu H. COVID-19: a novel coronavirus and a novel challenge for oral healthcare. Clinical Oral Investigations. PMID 32382932 DOI: 10.1007/s00784-020-03291-8  0.309
2020 Hu JJ, Liu X, Xia S, Zhang Z, Zhang Y, Zhao J, Ruan J, Luo X, Lou X, Bai Y, Wang J, Hollingsworth LR, Magupalli VG, Zhao L, Luo HR, ... ... Wu H, et al. FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation. Nature Immunology. PMID 32367036 DOI: 10.1038/S41590-020-0669-6  0.721
2020 Sadek J, Wuo MG, Rooklin D, Hauenstein A, Hong SH, Gautam A, Wu H, Zhang Y, Cesarman E, Arora PS. Modulation of virus-induced NF-κB signaling by NEMO coiled coil mimics. Nature Communications. 11: 1786. PMID 32286300 DOI: 10.1038/S41467-020-15576-3  0.798
2020 Guo J, Xie H, Mao S, Liang M, Wu H. Efficacy of hyaluronidase combined with corticosteroids in treatment of oral submucous fibrosis: a meta-analysis of randomised controlled clinical trials. Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. PMID 32145110 DOI: 10.1111/jop.13009  0.314
2019 Xia S, Ruan J, Wu H. Monitoring gasdermin pore formation in vitro. Methods in Enzymology. 625: 95-107. PMID 31455540 DOI: 10.1016/bs.mie.2019.04.024  0.745
2019 Xia S, Hollingsworth LR, Wu H. Mechanism and Regulation of Gasdermin-Mediated Cell Death. Cold Spring Harbor Perspectives in Biology. PMID 31451512 DOI: 10.1101/cshperspect.a036400  0.313
2019 Wu H, Arnold E. Michael G. Rossmann (1930-2019). Nature Structural & Molecular Biology. PMID 31285606 DOI: 10.1038/S41594-019-0271-5  0.488
2019 Xie H, Guo J, Tan B, Wu H. Efficacy of Salvia miltiorrhiza injection combined with steroids in the treatment of oral submucous fibrosis: A meta-analysis of randomized controlled trials. Medicine. 98: e16339. PMID 31277186 DOI: 10.1097/MD.0000000000016339  0.315
2019 Arnold E, Wu H, Johnson JE. Michael G. Rossmann (1930-2019), pioneer in macromolecular and virus crystallography: scientist, mentor and friend. Acta Crystallographica. Section D, Structural Biology. 75: 523-527. PMID 31205014 DOI: 10.1107/S2059798319008398  0.645
2019 Sharif H, Wang L, Wang WL, Magupalli VG, Andreeva L, Qiao Q, Hauenstein AV, Wu Z, Núñez G, Mao Y, Wu H. Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome. Nature. PMID 31189953 DOI: 10.1038/S41586-019-1295-Z  0.817
2019 Xia S, Wang L, Fu TM, Wu H. Mechanism of TRPM2 channel gating revealed by cryo-EM. The Febs Journal. PMID 31144442 DOI: 10.1111/febs.14939  0.674
2019 Shen C, Sharif H, Xia S, Wu H. Structural and mechanistic elucidation of inflammasome signaling by cryo-EM. Current Opinion in Structural Biology. 58: 18-25. PMID 31128494 DOI: 10.1016/J.Sbi.2019.03.033  0.574
2019 Lee YR, Chen M, Lee JD, Zhang J, Lin SY, Fu TM, Chen H, Ishikawa T, Chiang SY, Katon J, Zhang Y, Shulga YV, Bester AC, Fung J, Monteleone E, ... Wu H, et al. Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway. Science (New York, N.Y.). 364. PMID 31097636 DOI: 10.1126/Science.Aau0159  0.673
2019 Choi YJ, Kim S, Choi Y, Nielsen TB, Yan J, Lu A, Ruan J, Lee HR, Wu H, Spellberg B, Jung JU. Publisher Correction: SERPINB1-mediated checkpoint of inflammatory caspase activation. Nature Immunology. PMID 30846880 DOI: 10.1038/s41590-019-0361-x  0.665
2019 Pan L, Fu TM, Zhao W, Zhao L, Chen W, Qiu C, Liu W, Liu Z, Piai A, Fu Q, Chen S, Wu H, Chou JJ. Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling. Cell. PMID 30827683 DOI: 10.1016/j.cell.2019.02.001  0.705
2019 Choi YJ, Kim S, Choi Y, Nielsen TB, Yan J, Lu A, Ruan J, Lee HR, Wu H, Spellberg B, Jung JU. SERPINB1-mediated checkpoint of inflammatory caspase activation. Nature Immunology. PMID 30692621 DOI: 10.1038/s41590-018-0303-z  0.745
2019 Shen C, Lu A, Xie WJ, Ruan J, Negro R, Egelman EH, Fu TM, Wu H. Molecular mechanism for NLRP6 inflammasome assembly and activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30674671 DOI: 10.2210/Pdb6Ndj/Pdb  0.823
2018 Wang L, Fu TM, Zhou Y, Xia S, Greka A, Wu H. Structures and gating mechanism of human TRPM2. Science (New York, N.Y.). PMID 30467180 DOI: 10.1126/Science.Aav4809  0.682
2018 Luong PH, Hedl M, Yan J, Zuo T, Fu TM, Jiang X, Thiagarajah JR, Hansen SH, Lesser CF, Wu H, Abraham C, Lencer WI. INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling. Elife. 7. PMID 30355448 DOI: 10.7554/Elife.38539  0.702
2018 Li Y, Fu TM, Lu A, Witt K, Ruan J, Shen C, Wu H. Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1. Proceedings of the National Academy of Sciences of the United States of America. PMID 30279182 DOI: 10.1073/pnas.1810524115  0.832
2018 Ruan J, Xia S, Liu X, Lieberman J, Wu H. Cryo-EM structure of the gasdermin A3 membrane pore. Nature. PMID 29695864 DOI: 10.1038/s41586-018-0058-6  0.717
2018 Mompeán M, Li W, Li J, Laage S, Siemer AB, Bozkurt G, Wu H, McDermott AE. The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex. Cell. PMID 29681455 DOI: 10.1016/J.Cell.2018.03.032  0.653
2018 Annibaldi A, Wicky John S, Vanden Berghe T, Swatek KN, Ruan J, Liccardi G, Bianchi K, Elliott PR, Choi SM, Van Coillie S, Bertin J, Wu H, Komander D, Vandenabeele P, Silke J, et al. Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2. Molecular Cell. 69: 566-580.e5. PMID 29452637 DOI: 10.1016/J.Molcel.2018.01.027  0.722
2018 Xia S, Fu TM, Wu H. Inflammation NODs to Antagonists of RIP2-XIAP Interaction. Molecular Cell. 69: 535-536. PMID 29452633 DOI: 10.1016/j.molcel.2018.02.003  0.692
2018 Fu TM, Shen C, Li Q, Zhang P, Wu H. Mechanism of ubiquitin transfer promoted by TRAF6. Proceedings of the National Academy of Sciences of the United States of America. PMID 29432170 DOI: 10.1073/pnas.1721788115  0.702
2018 David L, Li Y, Ma J, Garner E, Zhang X, Wu H. Assembly mechanism of the CARMA1-BCL10-MALT1-TRAF6 signalosome. Proceedings of the National Academy of Sciences of the United States of America. PMID 29382759 DOI: 10.1073/pnas.1721967115  0.33
2017 Evavold CL, Ruan J, Tan Y, Xia S, Wu H, Kagan JC. The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages. Immunity. PMID 29195811 DOI: 10.1016/J.Immuni.2017.11.013  0.704
2017 Hauenstein AV, Xu G, Kabaleeswaran V, Wu H. Evidence for M1-linked Polyubiquitin-Mediated Conformational Change in NEMO. Journal of Molecular Biology. PMID 29111346 DOI: 10.1016/J.Jmb.2017.10.026  0.799
2017 Kleino A, Ramia NF, Bozkurt G, Shen Y, Nailwal H, Huang J, Napetschnig J, Gangloff M, Chan FK, Wu H, Li J, Silverman N. Peptidoglycan-Sensing Receptors Trigger the Formation of Functional Amyloids of the Adaptor Protein Imd to Initiate Drosophila NF-κB Signaling. Immunity. 47: 635-647.e6. PMID 29045898 DOI: 10.1016/J.Immuni.2017.09.011  0.662
2017 Sharif H, Li Y, Dong Y, Dong L, Wang WL, Mao Y, Wu H. Cryo-EM structure of the DNA-PK holoenzyme. Proceedings of the National Academy of Sciences of the United States of America. PMID 28652322 DOI: 10.1073/Pnas.1707386114  0.508
2017 Lamour G, Nassar R, Chan PH, Bozkurt G, Li J, Bui JM, Yip CK, Mayor T, Li H, Wu H, Gsponer JA. Mapping the Broad Structural and Mechanical Properties of Amyloid Fibrils. Biophysical Journal. 112: 584-594. PMID 28256219 DOI: 10.1016/J.Bpj.2016.12.036  0.601
2016 Fu TM, Li Y, Lu A, Li Z, Vajjhala PR, Cruz AC, Srivastava DB, DiMaio F, Penczek PA, Siegel RM, Stacey KJ, Egelman EH, Wu H. Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex. Molecular Cell. PMID 27746017 DOI: 10.1016/J.Molcel.2016.09.009  0.749
2016 Wang H, Horbinski C, Wu H, Liu Y, Sheng S, Liu J, Weiss H, Stromberg AJ, Wang C. NanoStringDiff: a novel statistical method for differential expression analysis based on NanoString nCounter data. Nucleic Acids Research. PMID 27471031 DOI: 10.1093/Nar/Gkw677  0.496
2016 Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J. Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores. Nature. 535: 153-158. PMID 27383986 DOI: 10.1038/Nature18629  0.731
2016 Zanoni I, Tan Y, Di Gioia M, Broggi A, Ruan J, Shi J, Donado CA, Shao F, Wu H, Springstead JR, Kagan JC. An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells. Science (New York, N.Y.). PMID 27103670 DOI: 10.1126/Science.Aaf3036  0.729
2016 Schmidt FI, Lu A, Chen JW, Ruan J, Tang C, Wu H, Ploegh HL. A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly. The Journal of Experimental Medicine. PMID 27069117 DOI: 10.1084/Jem.20151790  0.751
2016 Lu A, Li Y, Schmidt FI, Yin Q, Chen S, Fu TM, Tong AB, Ploegh HL, Mao Y, Wu H. Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism. Nature Structural & Molecular Biology. PMID 27043298 DOI: 10.1038/Nsmb.3199  0.812
2016 Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, ... ... Wu H, et al. Data publication with the structural biology data grid supports live analysis. Nature Communications. 7: 10882. PMID 26947396 DOI: 10.1038/Ncomms10882  0.498
2016 Fu Q, Fu TM, Cruz AC, Sengupta P, Thomas SK, Wang S, Siegel RM, Wu H, Chou JJ. Structural Basis and Functional Role of Intramembrane Trimerization of the Fas/CD95 Death Receptor. Molecular Cell. PMID 26853147 DOI: 10.1016/J.Molcel.2016.01.009  0.736
2015 Lu A, Li Y, Yin Q, Ruan J, Yu X, Egelman E, Wu H. Plasticity in PYD assembly revealed by cryo-EM structure of the PYD filament of AIM2. Cell Discovery. 1. PMID 26583071 DOI: 10.1038/celldisc.2015.13  0.778
2015 Ru H, Chambers MG, Fu TM, Tong AB, Liao M, Wu H. Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures. Cell. PMID 26548953 DOI: 10.1016/J.Cell.2015.10.055  0.683
2015 Vajjhala PR, Lu A, Brown DL, Pang SW, Sagulenko V, Sester DP, Cridland SO, Hill JM, Schroder K, Stow JL, Wu H, Stacey KJ. The inflammasome adaptor ASC induces procaspase-8 death effector domain filaments. The Journal of Biological Chemistry. PMID 26468282 DOI: 10.1074/jbc.M115.687731  0.303
2015 Zhang L, Chen S, Ruan J, Wu J, Tong AB, Yin Q, Li Y, David L, Lu A, Wang WL, Marks C, Ouyang Q, Zhang X, Mao Y, Wu H. Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization. Science (New York, N.Y.). PMID 26449474 DOI: 10.1126/science.aac5789  0.798
2015 Li L, Yin Q, Kuss P, Maliga Z, Millán JL, Wu H, Mitchison TJ. Erratum: Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs. Nature Chemical Biology. 11: 741. PMID 26284675 DOI: 10.1038/Nchembio0915-741C  0.462
2015 Hauenstein AV, Zhang L, Wu H. The hierarchical structural architecture of inflammasomes, supramolecular inflammatory machines. Current Opinion in Structural Biology. 31: 75-83. PMID 25881155 DOI: 10.1016/J.Sbi.2015.03.014  0.822
2015 Li L, Yin Q, Kuss P, Maliga Z, Millán JL, Wu H, Mitchison TJ. Corrigendum: Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs. Nature Chemical Biology. 11: 235. PMID 25689338 DOI: 10.1038/Nchembio0315-235D  0.468
2015 Chen L, Wang C, Qin ZS, Wu H. A novel statistical method for quantitative comparison of multiple ChIP-seq datasets. Bioinformatics (Oxford, England). 31: 1889-96. PMID 25682068 DOI: 10.1093/bioinformatics/btv094  0.51
2015 Yin Q, Fu TM, Li J, Wu H. Structural biology of innate immunity. Annual Review of Immunology. 33: 393-416. PMID 25622194 DOI: 10.1146/Annurev-Immunol-032414-112258  0.806
2015 Lu A, Wu H. Structural mechanisms of inflammasome assembly Febs Journal. 282: 435-444. PMID 25354325 DOI: 10.1111/febs.13133  0.331
2015 Wu H, Wang C, Wu Z. PROPER: comprehensive power evaluation for differential expression using RNA-seq. Bioinformatics (Oxford, England). 31: 233-41. PMID 25273110 DOI: 10.1093/Bioinformatics/Btu640  0.487
2014 Li L, Yin Q, Kuss P, Maliga Z, Millán JL, Wu H, Mitchison TJ. Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs. Nature Chemical Biology. 10: 1043-8. PMID 25344812 DOI: 10.1038/Nchembio.1661  0.549
2014 Ferrao R, Zhou H, Shan Y, Liu Q, Li Q, Shaw DE, Li X, Wu H. IRAK4 dimerization and trans-autophosphorylation are induced by Myddosome assembly. Molecular Cell. 55: 891-903. PMID 25201411 DOI: 10.1016/J.Molcel.2014.08.006  0.3
2014 Jang TH, Zheng C, Li J, Richards C, Hsiao YS, Walz T, Wu H, Park HH. Structural study of the RIPoptosome core reveals a helical assembly for kinase recruitment. Biochemistry. 53: 5424-31. PMID 25119434 DOI: 10.1021/Bi500585U  0.691
2014 Wu H, Williams J, Nathans J. Complete morphologies of basal forebrain cholinergic neurons in the mouse. Elife. 3: e02444. PMID 24894464 DOI: 10.7554/Elife.02444  0.392
2014 Lu A, Magupalli VG, Ruan J, Yin Q, Atianand MK, Vos MR, Schröder GF, Fitzgerald KA, Wu H, Egelman EH. Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes. Cell. 156: 1193-206. PMID 24630722 DOI: 10.1016/J.Cell.2014.02.008  0.8
2014 Lu A, Kabaleeswaran V, Fu T, Magupalli VG, Wu H. Crystal Structure of the F27G AIM2 PYD Mutant and Similarities of its Self-association to DED/DED Interactions Journal of Molecular Biology. 426: 1420-1427. PMID 24406744 DOI: 10.1016/J.Jmb.2013.12.029  0.736
2013 Qiao Q, Yang C, Zheng C, Fontán L, David L, Yu X, Bracken C, Rosen M, Melnick A, Egelman EH, Wu H. Structural architecture of the CARMA1/Bcl10/MALT1 signalosome: nucleation-induced filamentous assembly. Molecular Cell. 51: 766-79. PMID 24074955 DOI: 10.1016/J.Molcel.2013.08.032  0.326
2013 Li J, Yin Q, Wu H. Structural basis of signal transduction in the TNF receptor superfamily. Advances in Immunology. 119: 135-53. PMID 23886067 DOI: 10.1016/B978-0-12-407707-2.00005-9  0.735
2013 Yin Q, Sester DP, Tian Y, Hsiao YS, Lu A, Cridland JA, Sagulenko V, Thygesen SJ, Choubey D, Hornung V, Walz T, Stacey KJ, Wu H. Molecular mechanism for p202-mediated specific inhibition of AIM2 inflammasome activation. Cell Reports. 4: 327-39. PMID 23850291 DOI: 10.1016/J.Celrep.2013.06.024  0.598
2013 Lee JH, Yi L, Li J, Schweitzer K, Borgmann M, Naumann M, Wu H. Crystal structure and versatile functional roles of the COP9 signalosome subunit 1. Proceedings of the National Academy of Sciences of the United States of America. 110: 11845-50. PMID 23818606 DOI: 10.1073/Pnas.1302418110  0.674
2013 Kim S, Li L, Maliga Z, Yin Q, Wu H, Mitchison TJ. Anticancer flavonoids are mouse-selective STING agonists. Acs Chemical Biology. 8: 1396-401. PMID 23683494 DOI: 10.1021/Cb400264N  0.566
2013 Lu TT, Onizawa M, Hammer GE, Turer EE, Yin Q, Damko E, Agelidis A, Shifrin N, Advincula R, Barrera J, Malynn BA, Wu H, Ma A. Dimerization and ubiquitin mediated recruitment of A20, a complex deubiquitinating enzyme. Immunity. 38: 896-905. PMID 23602765 DOI: 10.1016/J.Immuni.2013.03.008  0.516
2013 Wu H, Wang C, Wu Z. A new shrinkage estimator for dispersion improves differential expression detection in RNA-seq data. Biostatistics (Oxford, England). 14: 232-43. PMID 23001152 DOI: 10.1093/Biostatistics/Kxs033  0.493
2012 Wu H, Williams J, Nathans J. Morphologic diversity of cutaneous sensory afferents revealed by genetically directed sparse labeling. Elife. 1: e00181. PMID 23256042 DOI: 10.7554/Elife.00181  0.42
2012 Li J, McQuade T, Siemer AB, Napetschnig J, Moriwaki K, Hsiao YS, Damko E, Moquin D, Walz T, McDermott A, Chan FK, Wu H. The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis. Cell. 150: 339-50. PMID 22817896 DOI: 10.1016/J.Cell.2012.06.019  0.645
2012 Yin Q, Tian Y, Kabaleeswaran V, Jiang X, Tu D, Eck MJ, Chen ZJ, Wu H. Cyclic di-GMP sensing via the innate immune signaling protein STING. Molecular Cell. 46: 735-45. PMID 22705373 DOI: 10.1016/J.Molcel.2012.05.029  0.69
2012 Ferrao R, Li J, Bergamin E, Wu H. Structural insights into the assembly of large oligomeric signalosomes in the Toll-like receptor-interleukin-1 receptor superfamily. Science Signaling. 5: re3. PMID 22649099 DOI: 10.1126/Scisignal.2003124  0.652
2011 Wu H, Lo YC, Yin Q. Structural studies of NEMO and TRAF6: implications in NF-κB activation. Advances in Experimental Medicine and Biology. 691: 89-91. PMID 21153312 DOI: 10.1007/978-1-4419-6612-4_9  0.571
2011 Zheng C, Yin Q, Wu H. Structural studies of NF-κB signaling. Cell Research. 21: 183-95. PMID 21135870 DOI: 10.1038/cr.2010.171  0.564
2010 Wang L, Yang JK, Kabaleeswaran V, Rice AJ, Cruz AC, Park AY, Yin Q, Damko E, Jang SB, Raunser S, Robinson CV, Siegel RM, Walz T, Wu H. The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations. Nature Structural & Molecular Biology. 17: 1324-9. PMID 20935634 DOI: 10.1038/Nsmb.1920  0.616
2009 Yin Q, Lamothe B, Darnay BG, Wu H. Structural basis for the lack of E2 interaction in the RING domain of TRAF2. Biochemistry. 48: 10558-67. PMID 19810754 DOI: 10.1021/bi901462e  0.635
2009 Yin Q, Lin SC, Lamothe B, Lu M, Lo YC, Hura G, Zheng L, Rich RL, Campos AD, Myszka DG, Lenardo MJ, Darnay BG, Wu H. E2 interaction and dimerization in the crystal structure of TRAF6. Nature Structural & Molecular Biology. 16: 658-66. PMID 19465916 DOI: 10.1038/nsmb.1605  0.584
2009 Wang R, Wei Z, Jin H, Wu H, Yu C, Wen W, Chan LN, Wen Z, Zhang M. Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor. Molecular Cell. 33: 692-703. PMID 19328064 DOI: 10.1016/J.Molcel.2009.02.016  0.306
2009 Pan W, da Graca LS, Shao Y, Yin Q, Wu H, Jiang X. PHAPI/pp32 suppresses tumorigenesis by stimulating apoptosis. The Journal of Biological Chemistry. 284: 6946-54. PMID 19121999 DOI: 10.1074/Jbc.M805801200  0.598
2007 Gao Z, Tian Y, Wang J, Yin Q, Wu H, Li YM, Jiang X. A dimeric Smac/diablo peptide directly relieves caspase-3 inhibition by XIAP. Dynamic and cooperative regulation of XIAP by Smac/Diablo. The Journal of Biological Chemistry. 282: 30718-27. PMID 17724022 DOI: 10.1074/Jbc.M705258200  0.616
2007 Lin SC, Huang Y, Lo YC, Lu M, Wu H. Crystal structure of the BIR1 domain of XIAP in two crystal forms. Journal of Molecular Biology. 372: 847-54. PMID 17698078 DOI: 10.1016/J.Jmb.2007.07.019  0.651
2007 Chung JY, Lu M, Yin Q, Lin SC, Wu H. Molecular basis for the unique specificity of TRAF6. Advances in Experimental Medicine and Biology. 597: 122-30. PMID 17633022 DOI: 10.1007/978-0-387-70630-6_10  0.567
2007 Chung JY, Lu M, Yin Q, Wu H. Structural revelations of TRAF2 function in TNF receptor signaling pathway. Advances in Experimental Medicine and Biology. 597: 93-113. PMID 17633020 DOI: 10.1007/978-0-387-70630-6_8  0.619
2007 Lu M, Lin SC, Huang Y, Kang YJ, Rich R, Lo YC, Myszka D, Han J, Wu H. XIAP induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1 dimerization. Molecular Cell. 26: 689-702. PMID 17560374 DOI: 10.1016/J.Molcel.2007.05.006  0.647
2007 Park HH, Logette E, Raunser S, Cuenin S, Walz T, Tschopp J, Wu H. Death domain assembly mechanism revealed by crystal structure of the oligomeric PIDDosome core complex. Cell. 128: 533-46. PMID 17289572 DOI: 10.1016/J.Cell.2007.01.019  0.3
2006 Yin Q, Park HH, Chung JY, Lin SC, Lo YC, da Graca LS, Jiang X, Wu H. Caspase-9 holoenzyme is a specific and optimal procaspase-3 processing machine. Molecular Cell. 22: 259-68. PMID 16630893 DOI: 10.1016/j.molcel.2006.03.030  0.597
2006 Park HH, Wu H. Crystal structure of RAIDD death domain implicates potential mechanism of PIDDosome assembly Journal of Molecular Biology. 357: 358-364. PMID 16434054 DOI: 10.1016/j.jmb.2005.12.082  0.318
2005 Yang JK, Wang L, Zheng L, Wan F, Ahmed M, Lenardo MJ, Wu H. Crystal structure of MC159 reveals molecular mechanism of DISC assembly and FLIP inhibition. Molecular Cell. 20: 939-49. PMID 16364918 DOI: 10.1016/j.molcel.2005.10.023  0.313
2004 Wu H. Assembly of post-receptor signaling complexes for the tumor necrosis factor receptor superfamily Advances in Protein Chemistry. 68: 225-279. PMID 15500863 DOI: 10.1016/S0065-3233(04)68007-7  0.305
2004 Huang Y, Lu M, Wu H. Antagonizing XIAP-mediated caspase-3 inhibition. Achilles' heel of cancers? Cancer Cell. 5: 1-2. PMID 14749118 DOI: 10.1016/S1535-6108(03)00340-4  0.611
2003 Huang Y, Rich RL, Myszka DG, Wu H. Requirement of both the second and third BIR domains for the relief of X-linked inhibitor of apoptosis protein (XIAP)-mediated caspase inhibition by Smac. The Journal of Biological Chemistry. 278: 49517-22. PMID 14512414 DOI: 10.1074/Jbc.M310061200  0.645
2003 Xu G, Rich RL, Steegborn C, Min T, Huang Y, Myszka DG, Wu H. Mutational analyses of the p35-caspase interaction. A bowstring kinetic model of caspase inhibition by p35. The Journal of Biological Chemistry. 278: 5455-61. PMID 12458208 DOI: 10.1074/Jbc.M211607200  0.62
2002 Moldovan MC, Yachou A, Lévesque K, Wu H, Hendrickson WA, Cohen EA, Sékaly RP. CD4 dimers constitute the functional component required for T cell activation Journal of Immunology. 169: 6261-6268. PMID 12444132 DOI: 10.4049/Jimmunol.169.11.6261  0.489
2001 Xu G, Cirilli M, Huang Y, Rich RL, Myszka DG, Wu H. Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex. Nature. 410: 494-7. PMID 11260720 DOI: 10.1038/35068604  0.608
2001 Huang Y, Park YC, Rich RL, Segal D, Myszka DG, Wu H. Structural Basis of Caspase Inhibition by XIAP Cell. 104: 781-790. DOI: 10.1016/S0092-8674(01)00273-2  0.626
1997 Wu H, Kwong PD, Hendrickson WA. Dimeric association and segmental variability in the structure of human CD4. Nature. 387: 527-30. PMID 9168119 DOI: 10.1038/387527A0  0.492
Low-probability matches (unlikely to be authored by this person)
2012 Ferrao R, Wu H. Helical assembly in the death domain (DD) superfamily Current Opinion in Structural Biology. 22: 241-247. PMID 22429337 DOI: 10.1016/J.Sbi.2012.02.006  0.3
2023 Du G, Healy LB, David L, Walker C, Fontana P, Dong Y, Devant P, Puthenveetil R, Ficarro SB, Banerjee A, Kagan JC, Lieberman J, Wu H. ROS-dependent palmitoylation is an obligate licensing modification for GSDMD pore formation. Biorxiv : the Preprint Server For Biology. PMID 36945424 DOI: 10.1101/2023.03.07.531538  0.3
2021 Andreeva L, David L, Rawson S, Shen C, Pasricha T, Pelegrin P, Wu H. NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation. Cell. PMID 34861190 DOI: 10.1016/j.cell.2021.11.011  0.299
2007 Feng W, Huang S, Wu H, Zhang M. Molecular basis of Bcl-xL's target recognition versatility revealed by the structure of Bcl-xL in complex with the BH3 domain of Beclin-1. Journal of Molecular Biology. 372: 223-35. PMID 17659302 DOI: 10.1016/J.Jmb.2007.06.069  0.298
2017 Yan F, Wang S, Yang W, Goldberg SN, Wu H, Duan WL, Deng ZT, Han HB, Zheng HR. Tumor-penetrating Peptide-integrated Thermally Sensitive Liposomal Doxorubicin Enhances Efficacy of Radiofrequency Ablation in Liver Tumors. Radiology. 162405. PMID 28631963 DOI: 10.1148/Radiol.2017162405  0.298
2021 Münzer P, Negro R, Fukui S, di Meglio L, Aymonnier K, Chu L, Cherpokova D, Gutch S, Sorvillo N, Shi L, Magupalli VG, Weber ANR, Scharf RE, Waterman CM, Wu H, et al. NLRP3 Inflammasome Assembly in Neutrophils Is Supported by PAD4 and Promotes NETosis Under Sterile Conditions. Frontiers in Immunology. 12: 683803. PMID 34122445 DOI: 10.3389/fimmu.2021.683803  0.297
2020 Wu H, Li SS, Zhou M, Jiang AN, He Y, Wang S, Yang W, Liu H. Palliative Radiofrequency Ablation Accelerates the Residual Tumor Progression Through Increasing Tumor-Infiltrating MDSCs and Reducing T-Cell-Mediated Anti-Tumor Immune Responses in Animal Model. Frontiers in Oncology. 10: 1308. PMID 33014771 DOI: 10.3389/fonc.2020.01308  0.295
2010 Jang TH, Zheng C, Wu H, Jeon JH, Park HH. In vitro reconstitution of the interactions in the PIDDosome Apoptosis. 15: 1444-1452. PMID 20872280 DOI: 10.1007/s10495-010-0544-2  0.295
2018 Wang W, Mao S, Yu H, Wu H, Shan X, Zhang X, Cui G, Liu X. Pinellia pedatisecta lectin exerts a proinflammatory activity correlated with ROS-MAPKs/NF-κB pathways and the NLRP3 inflammasome in RAW264.7 cells accompanied by cell pyroptosis. International Immunopharmacology. 66: 1-12. PMID 30415189 DOI: 10.1016/j.intimp.2018.11.002  0.294
2007 Lamothe B, Besse A, Campos AD, Webster WK, Wu H, Darnay BG. Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation. The Journal of Biological Chemistry. 282: 4102-12. PMID 17135271 DOI: 10.1074/jbc.M609503200  0.294
2024 Du G, Healy LB, David L, Walker C, El-Baba TJ, Lutomski CA, Goh B, Gu B, Pi X, Devant P, Fontana P, Dong Y, Ma X, Miao R, Balasubramanian A, ... ... Wu H, et al. ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D. Nature. PMID 38599239 DOI: 10.1038/s41586-024-07373-5  0.294
2007 Besse A, Lamothe B, Campos AD, Webster WK, Maddineni U, Lin SC, Wu H, Darnay BG. TAK1-dependent signaling requires functional interaction with TAB2/TAB3. The Journal of Biological Chemistry. 282: 3918-28. PMID 17158449 DOI: 10.1074/jbc.M608867200  0.292
2019 Wang L, Ferrao R, Li Q, Hatcher JM, Choi HG, Buhrlage SJ, Gray NS, Wu H. Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4). The Journal of Biological Chemistry. PMID 30679311 DOI: 10.1074/Jbc.Ra118.005428  0.291
2019 Wu H, Castenheira P, Faro C, Tang J. Cardosin A Endocytosis Mediated by Integrin Leads to Lysosome Leakage and Apoptosis of Epithelial Cells. Proteins. PMID 30785216 DOI: 10.1002/Prot.25672  0.288
2018 Feltham R, Jamal K, Tenev T, Liccardi G, Jaco I, Domingues CM, Morris O, John SW, Annibaldi A, Widya M, Kearney CJ, Clancy D, Elliott PR, Glatter T, Qiao Q, ... Wu H, et al. Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1's Cytotoxic Potential. Cell Reports. 23: 470-484. PMID 29642005 DOI: 10.1016/J.Celrep.2018.03.054  0.288
2022 Tang L, Dong S, Rasheed N, Wu HW, Zhou N, Li H, Wang M, Zheng J, He J, Chao WCH. Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP. Cell Reports. 41: 111732. PMID 36476863 DOI: 10.1016/j.celrep.2022.111732  0.288
2020 Wang L, Negro R, Wu H. TRPM2, linking oxidative stress and Ca permeation to NLRP3 inflammasome activation. Current Opinion in Immunology. 62: 131-135. PMID 32058297 DOI: 10.1016/j.coi.2020.01.005  0.288
2013 Wu H, Downs D, Ghosh K, Ghosh AK, Staib P, Monod M, Tang J. Candida albicans secreted aspartic proteases 4-6 induce apoptosis of epithelial cells by a novel Trojan horse mechanism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 2132-44. PMID 23430844 DOI: 10.1096/Fj.12-214353  0.286
2018 Orning P, Weng D, Starheim K, Ratner D, Best Z, Lee B, Brooks A, Xia S, Wu H, Kelliher MA, Berger SB, Gough PJ, Bertin J, Proulx MM, Goguen JD, et al. Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death. Science (New York, N.Y.). PMID 30361383 DOI: 10.1126/science.aau2818  0.285
2022 Wang S, Liu J, Wu H, Jiang A, Zhao K, Yan K, Wu W, Han H, Zhang Y, Yang W. All-trans retinoic acid (ATRA) inhibits insufficient radiofrequency ablation (IRFA)-induced enrichment of tumor-initiating cells in hepatocellular carcinoma. Chinese Journal of Cancer Research = Chung-Kuo Yen Cheng Yen Chiu. 33: 694-707. PMID 35125813 DOI: 10.21147/j.issn.1000-9604.2021.06.06  0.284
2023 Li G, Song Z, Ru Y, Zhang J, Luo L, Yang W, Wu H, Jin H, Bao X, Wei D, Yan Z, Qu H, Zhu Z, Xue X, Zhou G. Small-molecule nanoprodrug with high drug loading and EGFR, PI3K/AKT dual-inhibiting properties for bladder cancer treatment. Exploration (Beijing, China). 3: 20220141. PMID 37933289 DOI: 10.1002/EXP.20220141  0.284
2007 Park HH, Lo YC, Lin SC, Wang L, Yang JK, Wu H. The death domain superfamily in intracellular signaling of apoptosis and inflammation. Annual Review of Immunology. 25: 561-86. PMID 17201679 DOI: 10.1146/annurev.immunol.25.022106.141656  0.283
2018 Zhang F, Kang Y, Wang M, Li Y, Xu T, Yang W, Song H, Wu H, Shu Q, Jin P. Fragile X mental retardation protein modulates the stability of its m6A-marked messenger RNA targets. Human Molecular Genetics. PMID 30107516 DOI: 10.1093/Hmg/Ddy292  0.283
2007 Park HH, Wu H. Crystallization and preliminary X-ray crystallographic studies of the oligomeric death-domain complex between PIDD and RAIDD Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 63: 229-232. PMID 17329820 DOI: 10.1107/S1744309107007889  0.282
2017 Yu J, Wu H, Liu ZY, Zhu Q, Shan C, Zhang KQ. Advanced glycation end products induce the apoptosis of and inflammation in mouse podocytes through CXCL9-mediated JAK2/STAT3 pathway activation. International Journal of Molecular Medicine. PMID 28849106 DOI: 10.3892/ijmm.2017.3098  0.279
2010 Zheng C, Kabaleeswaran V, Wang Y, Cheng G, Wu H. Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation. Molecular Cell. 38: 101-13. PMID 20385093 DOI: 10.1016/J.Molcel.2010.03.009  0.279
2020 Meng X, Zhang J, Wu H, Yu D, Fang X. Aspartic Protease Amuc_1434* Inhibits Human Colorectal Cancer LS174T Cell Viability via TRAIL-Mediated Apoptosis Pathway. International Journal of Molecular Sciences. 21. PMID 32403433 DOI: 10.3390/ijms21093385  0.278
2016 Shao M, Li L, Song S, Wu W, Peng P, Yang C, Zhang M, Duan F, Jia D, Zhang J, Wu H, Zhao R, Wang L, Ruan Y, Gu J. E3 ubiquitin ligase CHIP interacts with C-type lectin-like receptor CLEC-2 and promotes its ubiquitin-proteasome degradation. Cellular Signalling. 28: 1530-1536. PMID 27443248 DOI: 10.1016/j.cellsig.2016.07.007  0.278
2007 Feng W, Wu H, Chan LN, Zhang M. The Par-3 NTD adopts a PB1-like structure required for Par-3 oligomerization and membrane localization. The Embo Journal. 26: 2786-96. PMID 17476308 DOI: 10.1038/Sj.Emboj.7601702  0.277
2023 Fan P, Meng H, Hao W, Zheng Y, Li H, Zhang Z, Du L, Guo X, Wang D, Wang Y, Wu H. Cardamonin targets KEAP1/NRF2 signaling for protection against atherosclerosis. Food & Function. PMID 37157847 DOI: 10.1039/d3fo00967j  0.277
2022 Dong Y, Pi X, Bartels-Burgahn F, Saltukoglu D, Liang Z, Yang J, Alt FW, Reth M, Wu H. Structural principles of B-cell antigen receptor assembly. Nature. PMID 36228656 DOI: 10.1038/s41586-022-05412-7  0.277
2023 Li J, Wang W, Yuan Y, Cui X, Bian H, Wen H, Zhang X, Yu H, Wu H. Pinellia ternata lectin induces inflammation through TLR4 receptor and mediates PI3K/Akt/mTOR axis to regulate NF-κB signaling pathway. Toxicology. 153430. PMID 36669722 DOI: 10.1016/j.tox.2023.153430  0.276
2020 Hou S, Zhang X, Du H, Ning X, Wu H, Li C, Liu Y, Sun Z, Du Z, Jin M. Silica nanoparticles induce mitochondrial pathway-dependent apoptosis by activating unfolded protein response in human neuroblastoma cells. Environmental Toxicology. PMID 33270327 DOI: 10.1002/tox.23071  0.276
2023 Du T, Song Y, Ray A, Yao Y, Samur MK, Shen C, Penailillo J, Sewastianik T, Tai YT, Fulciniti M, Munshi NC, Wu H, Carrasco RD, Chauhan D, Anderson KC, et al. Ubiquitin receptor PSMD4/Rpn10 is a novel therapeutic target in multiple myeloma. Blood. PMID 36630605 DOI: 10.1182/blood.2022017897  0.276
2021 Hu S, Li Y, Nie C, Zhang J, Bai X, Wu H, Shen T, Hu W, Wang J. Structure and pro-inflammatory activities of bran polysaccharides from a novel wheat kernel. Journal of Food Biochemistry. e14008. PMID 34811774 DOI: 10.1111/jfbc.14008  0.276
2018 Liu D, Wu H, Wang C, Li Y, Tian H, Siraj S, Sehgal SA, Wang X, Wang J, Shang Y, Jiang Z, Liu L, Chen Q. STING directly activates autophagy to tune the innate immune response. Cell Death and Differentiation. PMID 30568238 DOI: 10.1038/s41418-018-0251-z  0.275
2006 Guasparri I, Wu H, Cesarman E. The KSHV oncoprotein vFLIP contains a TRAF-interacting motif and requires TRAF2 and TRAF3 for signalling. Embo Reports. 7: 114-9. PMID 16311516 DOI: 10.1038/Sj.Embor.7400580  0.275
2020 He Y, Su W, He X, Chen T, Zeng X, Yan Z, Zhang W, Yang W, Guo J, Wu H. Pharmacokinetics and biotransformation investigation in beagle dog of active compounds from naoxintong capsule. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 133: 110940. PMID 33227707 DOI: 10.1016/j.biopha.2020.110940  0.275
2012 Feldman T, Kabaleeswaran V, Jang SB, Antczak C, Djaballah H, Wu H, Jiang X. A class of allosteric caspase inhibitors identified by high-throughput screening. Molecular Cell. 47: 585-95. PMID 22795132 DOI: 10.1016/J.Molcel.2012.06.007  0.274
2020 Hauseman ZJ, Harvey EP, Newman CE, Wales TE, Bucci JC, Mintseris J, Schweppe DK, David L, Fan L, Cohen DT, Herce HD, Mourtada R, Ben-Nun Y, Bloch NB, Hansen SB, ... Wu H, et al. Homogeneous Oligomers of Pro-apoptotic BAX Reveal Structural Determinants of Mitochondrial Membrane Permeabilization. Molecular Cell. PMID 32533918 DOI: 10.1016/J.Molcel.2020.05.029  0.274
2010 Lin SC, Lo YC, Wu H. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature. 465: 885-90. PMID 20485341 DOI: 10.1038/nature09121  0.274
2021 Bittner ZA, Liu X, Mateo Tortola M, Tapia-Abellán A, Shankar S, Andreeva L, Mangan M, Spalinger M, Kalbacher H, Düwell P, Lovotti M, Bosch K, Dickhöfer S, Marcu A, Stevanović S, ... ... Wu H, et al. BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity. The Journal of Experimental Medicine. 218. PMID 34554188 DOI: 10.1084/jem.20201656  0.274
2023 Du G, Zhao L, Zheng Y, Belfetmi A, Cai T, Xu B, Heyninck K, Van Den Heede K, Buyse MA, Fontana P, Bowman M, Lin LL, Wu H, Chou JJ. Autoinhibitory structure of preligand association state implicates a new strategy to attain effective DR5 receptor activation. Cell Research. PMID 36604598 DOI: 10.1038/s41422-022-00755-2  0.273
2023 Cai J, Wu H, Wang C, Chen Y, Zhang D, Guan S, Fu B, Jin Y, Qian C. Sec1 regulates intestinal mucosal immunity in a mouse model of inflammatory bowel disease. Bmc Immunology. 24: 51. PMID 38066482 DOI: 10.1186/s12865-023-00578-9  0.273
2008 Feng W, Wu H, Chan LN, Zhang M. Par-3-mediated junctional localization of the lipid phosphatase PTEN is required for cell polarity establishment. The Journal of Biological Chemistry. 283: 23440-9. PMID 18550519 DOI: 10.1074/Jbc.M802482200  0.273
2017 Choi JY, Qiao Q, Hong SH, Kim CM, Jeong JH, Kim YG, Jung YK, Wu H, Park HH. CIDE domains form functionally important higher-order assemblies for DNA fragmentation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28652364 DOI: 10.1073/pnas.1705949114  0.272
2015 Wu H, Liu Q, Cai T, Chen YD, Wang ZF. Induction of microRNA-146a is involved in curcumin-mediated enhancement of temozolomide cytotoxicity against human glioblastoma. Molecular Medicine Reports. PMID 26239619 DOI: 10.3892/mmr.2015.4087  0.272
2021 Huang B, Jiang Z, Wu S, Wu H, Zhang X, Chen J, Zhao F, Liu J. RCAN1.4 suppresses the osteosarcoma growth and metastasis via interfering with the calcineurin/NFAT signaling pathway. Journal of Bone Oncology. 30: 100383. PMID 34336566 DOI: 10.1016/j.jbo.2021.100383  0.272
2014 Yang C, David L, Qiao Q, Damko E, Wu H. The CBM signalosome: potential therapeutic target for aggressive lymphoma? Cytokine & Growth Factor Reviews. 25: 175-83. PMID 24411492 DOI: 10.1016/J.Cytogfr.2013.12.008  0.272
2017 Yi L, Bozkurt G, Li Q, Lo S, Menon AK, Wu H. Disulfide Bond Formation and N-Glycosylation Modulate Protein-Protein Interactions in GPI-Transamidase (GPIT). Scientific Reports. 8: 45912. PMID 28374821 DOI: 10.1038/Srep45912  0.271
2022 Zhang X, Hao H, Ma K, Pang H, Li X, Tian T, Hou S, Ning X, Wu H, Hou Q, Li M, Sun Y, Song X, Jin M. The role and mechanism of unfolded protein response signaling pathway in methylmercury-induced apoptosis of mouse spermatocytes germ cell-2 cells. Environmental Toxicology. PMID 36330985 DOI: 10.1002/tox.23684  0.271
2022 Jiang AN, Wang B, Wang S, Zhao K, Wu H, Yan K, Wu W, Yang W. The study of direct and indirect effects of radiofrequency ablation on tumor microenvironment in liver tumor animal model. Bmc Cancer. 22: 663. PMID 35710408 DOI: 10.1186/s12885-022-09730-x  0.271
2010 Wu H, Sun L, Blombach F, Brouns SJ, Snijders AP, Lorenzen K, van den Heuvel RH, Heck AJ, Fu S, Li X, Zhang XC, Rao Z, van der Oost J. Structure of the ribosome associating GTPase HflX. Proteins. 78: 705-13. PMID 19787775 DOI: 10.1002/Prot.22599  0.271
2021 Liu X, Xia S, Zhang Z, Wu H, Lieberman J. Channelling inflammation: gasdermins in physiology and disease. Nature Reviews. Drug Discovery. PMID 33692549 DOI: 10.1038/s41573-021-00154-z  0.27
2004 Ye H, Chen T, Xu X, Pennycooke M, Wu H, Steegborn C. Crystal structure of the putative adapter protein MTH1859. Journal of Structural Biology. 148: 251-256. PMID 15477104 DOI: 10.1016/J.Jsb.2004.06.004  0.27
2015 Qiao Q, Wu H. Supramolecular organizing centers (SMOCs) as signaling machines in innate immune activation. Science China. Life Sciences. PMID 26511517 DOI: 10.1007/s11427-015-4951-z  0.27
2022 Hou S, Zhang X, Ning X, Wu H, Li X, Ma K, Hao H, Lv C, Li C, Du Z, Du H, Jin M. Methylmercury induced apoptosis of human neuroblastoma cells through the reactive oxygen species mediated caspase and poly ADP-ribose polymerase/apoptosis-inducing factor dependent pathways. Environmental Toxicology. PMID 35396826 DOI: 10.1002/tox.23535  0.27
2023 Fu W, Xiao Z, Chen Y, Pei J, Sun Y, Zhang Z, Wu H, Pei Y, Wei S, Wang Y, Wang D. Molecular integrative study on interaction domains of nuclear factor erythroid 2-related factor 2 with sirtuin 6. Biochimie. 211: 68-77. PMID 36924820 DOI: 10.1016/j.biochi.2023.03.002  0.27
2009 de Koning B, Blombach F, Wu H, Brouns SJ, van der Oost J. Role of multiprotein bridging factor 1 in archaea: bridging the domains? Biochemical Society Transactions. 37: 52-7. PMID 19143601 DOI: 10.1042/BST0370052  0.269
2011 Xu G, Lo YC, Li Q, Napolitano G, Wu X, Jiang X, Dreano M, Karin M, Wu H. Crystal structure of inhibitor of κB kinase β. Nature. 472: 325-30. PMID 21423167 DOI: 10.1038/nature09853  0.269
2014 Wu H, Xue D, Chen G, Han Z, Huang L, Zhu C, Wang X, Jin H, Wang J, Zhu Y, Liu L, Chen Q. The BCL2L1 and PGAM5 axis defines hypoxia-induced receptor-mediated mitophagy. Autophagy. 10: 1712-25. PMID 25126723 DOI: 10.4161/auto.29568  0.269
2021 Li C, Liu F, Yang X, Guo B, Li G, Yin J, He G, Yang C, Xu L, Li S, Wu H, Liu H, Ruan Y, Gu J, Wang L. Targeting lectin-like oxidized low-density lipoprotein receptor-1 triggers autophagic program in esophageal cancer. Cell Death and Differentiation. PMID 34611296 DOI: 10.1038/s41418-021-00884-y  0.269
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2018 Shi F, Zhang J, Liu H, Wu L, Jiang H, Wu Q, Liu T, Lou M, Wu H. The dual PI3K/mTOR inhibitor dactolisib elicits anti-tumor activity in vitro and in vivo. Oncotarget. 9: 706-717. PMID 29416647 DOI: 10.18632/oncotarget.23091  0.243
2019 Meng X, Wang W, Lan T, Yang W, Yu D, Fang X, Wu H. A Purified Aspartic Protease from Plays an Important Role in Degrading Muc2. International Journal of Molecular Sciences. 21. PMID 31861919 DOI: 10.3390/ijms21010072  0.243
2022 Wu T, Zhang B, Lu J, Huang A, Wu H, Qiao J, Ruan H. Label-free relative quantitative proteomics reveals extracellular vesicles as a vehicle for effector protein delivery. Frontiers in Microbiology. 13: 1042111. PMID 36590436 DOI: 10.3389/fmicb.2022.1042111  0.243
2021 Hou J, Zhang L, Wu H, Gao P, Xu Z. Increased Tim-3 monocytes/macrophages are associated with disease severity in patients with IgA nephropathy. International Immunopharmacology. 97: 107666. PMID 34058623 DOI: 10.1016/j.intimp.2021.107666  0.243
2019 Tower-Gilchrist C, Zlatic SA, Yu D, Chang Q, Wu H, Lin X, Faundez V, Chen P. Adaptor protein-3 complex is required for Vangl2 trafficking and planar cell polarity of the inner ear. Molecular Biology of the Cell. mbcE16080592. PMID 31268833 DOI: 10.1091/Mbc.E16-08-0592  0.243
2021 Yang M, Guan S, Tao J, Zhu K, Lv D, Wang J, Li G, Gao Y, Wu H, Liu J, Cao L, Fu Y, Ji P, Lian Z, Zhang L, et al. Melatonin promotes male reproductive performance and increases testosterone synthesis in mammalian Leydig cells. Biology of Reproduction. PMID 33709108 DOI: 10.1093/biolre/ioab046  0.243
2016 Hu L, Lu J, Chiang H, Wu H, Edge AS, Shi F. Diphtheria Toxin-Induced Cell Death Triggers Wnt-Dependent Hair Cell Regeneration in Neonatal Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 9479-89. PMID 27605621 DOI: 10.1523/JNEUROSCI.2447-15.2016  0.243
2022 Chen H, Zhang T, Zhang Y, Wu H, Fang Z, Liu Y, Chen Y, Wang Z, Jia S, Ji X, Shang L, Du F, Liu J, Lu M, Chong W. Deciphering the tumor cell-infiltrating landscapes reveal microenvironment subtypes and therapeutic potentials for nonsquamous NSCLC. Jci Insight. PMID 35511432 DOI: 10.1172/jci.insight.152815  0.243
2010 Wu H, Brennwald P. The function of two Rho family GTPases is determined by distinct patterns of cell surface localization Molecular and Cellular Biology. 30: 5207-5217. PMID 20823269 DOI: 10.1128/Mcb.00366-10  0.243
2022 Chen L, Zhu B, Ru G, Meng H, Yan Y, Hong M, Zhang D, Luan C, Zhang S, Wu H, Gao H, Bai S, Li C, Ding R, Xue N, et al. Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing. Nature Biotechnology. PMID 36357717 DOI: 10.1038/s41587-022-01532-7  0.243
2018 Wu H, Ting JM, Werba O, Meng S, Tirrell MV. Non-equilibrium phenomena and kinetic pathways in self-assembled polyelectrolyte complexes. The Journal of Chemical Physics. 149: 163330. PMID 30384688 DOI: 10.1063/1.5039621  0.242
2017 Yu H, Liu L, Wang K, Wu H, Wang W, Zhang X, Cui G, Cui X, Huang J. Upregulation of aquaporin 3 expression by diterpenoids in Euphorbia pekinensis is associated with activation of the NF-κB signaling pathway in the co-culture system of HT-29 and RAW 264.7 cells. Biochimie. PMID 29129744 DOI: 10.1016/j.biochi.2017.11.006  0.242
2022 Bai N, Riching KM, Makaju A, Wu H, Acker TM, Ou SC, Zhang Y, Shen X, Bulloch D, Rui H, Gibson B, Daniels DL, Urh M, Rock B, Humphreys SC. Modeling the CRL4A ligase complex to predict target protein ubiquitination induced by cereblon-recruiting PROTACs. The Journal of Biological Chemistry. 101653. PMID 35101445 DOI: 10.1016/j.jbc.2022.101653  0.242
2015 Wu H, Lu MH, Wang W, Zhang MY, Zhu QQ, Xia YY, Xu RX, Yang Y, Chen LH, Ma QH. Lamotrigine Reduces β-Site AβPP-Cleaving Enzyme 1 Protein Levels Through Induction of Autophagy. Journal of Alzheimer's Disease : Jad. PMID 25854934 DOI: 10.3233/JAD-143162  0.242
2020 Wang Z, Chen H, Xue L, He W, Jiang L, Wang Z, Wu H. Proteomic screening identifies PML/p53 axis as a potential treatment target of facial nerve schwannomas. American Journal of Translational Research. 12: 4237-4250. PMID 32913501  0.242
2018 Wu H, Xu X, Li J, Gong J, Li M. TIM‑4 blockade of KCs combined with exogenous TGF‑β injection helps to reverse acute rejection and prolong the survival rate of mice receiving liver allografts. International Journal of Molecular Medicine. PMID 29620252 DOI: 10.3892/ijmm.2018.3606  0.242
2022 Junqueira C, Crespo Â, Ranjbar S, de Lacerda LB, Lewandrowski M, Ingber J, Parry B, Ravid S, Clark S, Schrimpf MR, Ho F, Beakes C, Margolin J, Russell N, Kays K, ... ... Wu H, et al. FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation. Nature. PMID 35385861 DOI: 10.1038/s41586-022-04702-4  0.242
2017 Maier A, Wu H, Cordasic N, Oefner P, Dietel B, Thiele C, Weidemann A, Eckardt KU, Warnecke C. Hypoxia-inducible protein 2 Hig2/Hilpda mediates neutral lipid accumulation in macrophages and contributes to atherosclerosis in apolipoprotein E-deficient mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28760743 DOI: 10.1096/Fj.201700235R  0.242
2023 Liu R, Li T, Xu H, Yu G, Zhang T, Wang J, Sun Y, Bi Y, Feng X, Wu H, Zhang C, Sun Y. Systems biology strategy through integrating metabolomics and network pharmacology to reveal the mechanisms of Xiaopi Hewei Capsule improves functional dyspepsia. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1226: 123676. PMID 37329776 DOI: 10.1016/j.jchromb.2023.123676  0.242
2022 Liu P, Xie XR, Wu H, Li H, Chi JS, Liu XM, Luo J, Tang Y, Xu CX. Conditioned medium of mesenchymal stem cells pretreated with HO promotes intestinal mucosal repair in acute experimental colitis. Scientific Reports. 12: 20772. PMID 36456585 DOI: 10.1038/s41598-022-24493-y  0.241
2021 Wu H, Zheng S, Zhang J, Xu S, Miao Z. Cadmium induces endoplasmic reticulum stress-mediated apoptosis in pig pancreas via the increase of Th1 cells. Toxicology. 152790. PMID 33891997 DOI: 10.1016/j.tox.2021.152790  0.241
2017 Liu J, Yao X, Wu D, Ye Y, Wu Q, Liu S, Wu H. Effect of TW37 on the growth of H1975 EGFR‑TKI‑resistant lung cancer cells and its underlying mechanisms. Molecular Medicine Reports. PMID 29207200 DOI: 10.3892/mmr.2017.8181  0.241
2020 Wu H, Gontarek BC, Yi G, Beall BD, Neelakandan AK, Adhikari B, Chen R, McCarty DR, Severin A, Becraft PW. The thick aleurone1 gene encodes a NOT1 subunit of the CCR4-NOT complex and regulates cell patterning in endosperm. Plant Physiology. PMID 32737073 DOI: 10.1104/Pp.20.00703  0.241
2020 Bhattacharjee S, Lee Y, Zhu B, Wu H, Chen Y, Chen H. Epsins in vascular development, function and disease. Cellular and Molecular Life Sciences : Cmls. PMID 32930806 DOI: 10.1007/s00018-020-03642-4  0.241
2020 Wang XZ, Feng Y, Han YF, Bian Y, Liang J, Wen HM, Wu H. Budlein A methylacrylate demonstrates potent activity against triple-negative breast cancer by targeting IκBα kinase and exportin-1. Toxicology and Applied Pharmacology. 115263. PMID 33022283 DOI: 10.1016/j.taap.2020.115263  0.241
2021 Sun Z, Yu H, Zhao J, Tan T, Pan H, Zhu Y, Chen L, Zhang C, Zhang L, Lei A, Xu Y, Bi X, Huang X, Gao B, Wang L, ... ... Wu H, et al. LIN28 coordinately promotes nucleolar/ribosomal functions and represses the 2C-like transcriptional program in pluripotent stem cells. Protein & Cell. PMID 34331666 DOI: 10.1007/s13238-021-00864-5  0.24
2020 Yang K, Zhao Y, Nie X, Wu H, Wang B, Almodovar-Rivera CM, Xie H, Tang W. A Cell-Based Target Engagement Assay for the Identification of Cereblon E3 Ubiquitin Ligase Ligands and Their Application in HDAC6 Degraders. Cell Chemical Biology. PMID 32413286 DOI: 10.1016/J.Chembiol.2020.04.008  0.24
2019 Mao Y, Huang Y, Zhang Y, Wang C, Wu H, Tian X, Liu Y, Hou B, Liang Y, Rong H, Gu X, Ma Z. Cannabinoid receptor 2‑selective agonist JWH015 attenuates bone cancer pain through the amelioration of impaired autophagy flux induced by inflammatory mediators in the spinal cord. Molecular Medicine Reports. PMID 31661120 DOI: 10.3892/mmr.2019.10772  0.24
2021 Miao Z, Miao Z, Wang S, Wu H, Xu S. Exposure to imidacloprid induce oxidative stress, mitochondrial dysfunction, inflammation, apoptosis and mitophagy via NF-kappaB/JNK pathway in grass carp hepatocytes. Fish & Shellfish Immunology. PMID 34954370 DOI: 10.1016/j.fsi.2021.12.017  0.24
2020 Wang Z, Qian M, Wang Q, Liu H, Wu H, Huang Z. An In Vitro Study on Prestin Analog Gene in the Bullfrog Hearing Organs. Neural Plasticity. 2020: 3570732. PMID 32714383 DOI: 10.1155/2020/3570732  0.24
2015 Wu H, Xu LL, Teuscher P, Liu H, Kaplan MH, Dent AL. An Inhibitory Role for the Transcription Factor Stat3 in Controlling IL-4 and Bcl6 Expression in Follicular Helper T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 26188063 DOI: 10.4049/Jimmunol.1500335  0.24
2010 Wu H, Panakanti R, Li F, Mahato RI. XIAP gene expression protects β-cells and human islets from apoptotic cell death. Molecular Pharmaceutics. 7: 1655-66. PMID 20677802 DOI: 10.1021/Mp100070J  0.24
2017 Sun W, Liu X, Zhang H, Song Y, Li T, Liu X, Liu Y, Guo L, Wang F, Yang T, Guo W, Wu J, Jin H, Wu H. Epigallocatechin Gallate Upregulates NRF2 to Prevent Diabetic Nephropathy via Disabling KEAP1. Free Radical Biology & Medicine. PMID 28457936 DOI: 10.1016/j.freeradbiomed.2017.04.365  0.239
2011 Wu H, Ge J, Yang PY, Wang J, Uttamchandani M, Yao SQ. A peptide aldehyde microarray for high-throughput profiling of cellular events. Journal of the American Chemical Society. 133: 1946-54. PMID 21247160 DOI: 10.1021/Ja109597V  0.239
2022 Wu H, Xu T, Chen T, Liu J, Xu S. Oxidative stress mediated by the TLR4/NOX2 signalling axis is involved in polystyrene microplastic-induced uterine fibrosis in mice. The Science of the Total Environment. 155825. PMID 35597360 DOI: 10.1016/j.scitotenv.2022.155825  0.239
2020 Jiang T, Wu H, Lin M, Yin J, Tan L, Ruan Y, Feng M. B4GALNT1 promotes progression and metastasis in lung adenocarcinoma through JNK/c-Jun/Slug pathway. Carcinogenesis. PMID 33367717 DOI: 10.1093/carcin/bgaa141  0.239
2016 Wu H, Lin J, Liu P, Huang Z, Zhao P, Jin H, Ma J, Wen L, Gu N. Reactive oxygen species acts as executor in radiation enhancement and autophagy inducing by AgNPs. Biomaterials. 101: 1-9. PMID 27254247 DOI: 10.1016/j.biomaterials.2016.05.031  0.239
2022 Zhu W, Zhang Y, Li Y, Wu H. Glaucocalyxin A Attenuates IL-1-Induced Inflammatory Response and Cartilage Degradation in Osteoarthritis Chondrocytes via Inhibiting the Activation of NF-B Signaling Pathway. Disease Markers. 2022: 6516246. PMID 35256893 DOI: 10.1155/2022/6516246  0.239
2022 Bram Y, Duan X, Nilsson-Payant BE, Chandar V, Wu H, Shore D, Fajardo A, Sinha S, Hassan N, Weinstein H, TenOever BR, Chen S, Schwartz RE. Dual-Reporter System for Real-Time Monitoring of SARS-CoV-2 Main Protease Activity in Live Cells Enables Identification of an Allosteric Inhibition Path. Acs Bio & Med Chem Au. 2: 627-641. PMID 36570071 DOI: 10.1021/acsbiomedchemau.2c00034  0.239
2017 Yang W, Wu H, Zhang ZY, Lee JC, Wang S, Wang YJ, Wu W, Chen MH, Yan K. Long-term outcome of percutaneous radiofrequency ablation in recurrent hepatocellular carcinoma after liver transplantation. International Journal of Hyperthermia : the Official Journal of European Society For Hyperthermic Oncology, North American Hyperthermia Group. 1-9. PMID 28540818 DOI: 10.1080/02656736.2017.1324179  0.239
2020 Zhang L, Gao Y, Zhang R, Sun F, Cheng C, Qian F, Duan X, Wei G, Sun C, Pang X, Chen P, Chai R, Yang T, Wu H, Liu D. THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis. Plos Genetics. 16: e1008953. PMID 32776944 DOI: 10.1371/Journal.Pgen.1008953  0.239
2016 Fu J, Yang W, Wang S, Bai J, Wu H, Wang H, Yan K, Chen M. Clinical value of contrast-enhanced ultrasound in improving diagnostic accuracy rate of transthoracic biopsy of anterior-medial mediastinal lesions. Chinese Journal of Cancer Research = Chung-Kuo Yen Cheng Yen Chiu. 28: 617-625. PMID 28174490 DOI: 10.21147/j.issn.1000-9604.2016.06.08  0.239
2022 Zhang B, Liu P, Li Y, Hu Q, Li H, Pang X, Wu H. Multi-omics analysis of kinesin family member 2C in human tumors: novel prognostic biomarker and tumor microenvironment regulator. American Journal of Cancer Research. 12: 4954-4976. PMID 36504885  0.238
2019 Wu H, Chen G, Wang J, Deng M, Yuan F, Gong J. TIM-4 interference in Kupffer cells against CCL4-induced liver fibrosis by mediating Akt1/Mitophagy signalling pathway. Cell Proliferation. e12731. PMID 31755616 DOI: 10.1111/cpr.12731  0.238
2015 Wu H, Zhang K, Liu Y, Wang H, Wu J, Zhu F, Zou P. Binding-induced and label-free colorimetric method for protein detection based on autonomous assembly of hemin/G-quadruplex DNAzyme amplification strategy. Biosensors & Bioelectronics. 64: 572-8. PMID 25310491 DOI: 10.1016/j.bios.2014.09.096  0.238
2010 Zhu H, Yue J, Pan Z, Wu H, Cheng Y, Lu H, Ren X, Yao M, Shen Z, Yang JM. Involvement of Caveolin-1 in repair of DNA damage through both homologous recombination and non-homologous end joining. Plos One. 5: e12055. PMID 20700465 DOI: 10.1371/Journal.Pone.0012055  0.238
2017 Li C, Zhang J, Wu H, Li L, Yang C, Song S, Peng P, Shao M, Zhang M, Zhao J, Zhao R, Wu W, Ruan Y, Wang L, Gu J. Lectin-like oxidized low-density lipoprotein receptor-1 facilitates metastasis of gastric cancer through driving epithelial-mesenchymal transition and PI3K/Akt/GSK3β activation. Scientific Reports. 7: 45275. PMID 28345638 DOI: 10.1038/srep45275  0.238
2018 Yu GT, Mao L, Wu L, Deng WW, Bu LL, Liu JF, Chen L, Yang LL, Wu H, Zhang WF, Sun ZJ. Inhibition of SRC family kinases facilitates anti-CTLA4 immunotherapy in head and neck squamous cell carcinoma. Cellular and Molecular Life Sciences : Cmls. PMID 29955905 DOI: 10.1007/s00018-018-2863-3  0.238
2023 Bao S, Yu D, Tang Z, Wu H, Zhang H, Wang N, Liu Y, Huang H, Liu C, Li X, Guo Z. Conformationally regulated "nanozyme-like" cerium oxide with multiple free radical scavenging activities for osteoimmunology modulation and vascularized osseointegration. Bioactive Materials. 34: 64-79. PMID 38186961 DOI: 10.1016/j.bioactmat.2023.12.006  0.238
2017 Yu W, Zhang X, Wu H, Zhou Q, Wang Z, Liu R, Liu J, Wang X, Hai C. HO-1 Is Essential for Tetrahydroxystilbene Glucoside Mediated Mitochondrial Biogenesis and Anti-Inflammation Process in LPS-Treated RAW264.7 Macrophages. Oxidative Medicine and Cellular Longevity. 2017: 1818575. PMID 28473878 DOI: 10.1155/2017/1818575  0.238
2019 Wu H, Zhu H, Zhuang Y, Zhang J, Ding X, Zhan L, Luo S, Zhang Q, Sun F, Zhang M, Pan Z, Lu Y. LncRNA ACART protects cardiomyocytes from apoptosis by activating PPAR-γ/Bcl-2 pathway. Journal of Cellular and Molecular Medicine. PMID 31749326 DOI: 10.1111/jcmm.14781  0.238
2023 Wu H, Zhang L, Zhao B, Yang W, Galluzzi M. Deep learning strategy for small dataset from atomic force microscopy mechano-imaging on macrophages phenotypes. Frontiers in Bioengineering and Biotechnology. 11: 1259979. PMID 37860624 DOI: 10.3389/fbioe.2023.1259979  0.238
2006 Lu M, Min T, Eliezer D, Wu H. Native chemical ligation in covalent caspase inhibition by p35. Chemistry & Biology. 13: 117-22. PMID 16492559 DOI: 10.1016/J.Chembiol.2005.12.007  0.238
2018 Yao B, Li Y, Wang Z, Chen L, Poidevin M, Zhang C, Lin L, Wang F, Bao H, Jiao B, Lim J, Cheng Y, Huang L, Phillips BL, Xu T, ... ... Wu H, et al. Active N-Methyladenine Demethylation by DMAD Regulates Gene Expression by Coordinating with Polycomb Protein in Neurons. Molecular Cell. PMID 30078725 DOI: 10.1016/J.Molcel.2018.07.005  0.238
2021 Wu H, Xu H, Jia D, Li T, Xia L. METTL3-induced UCK2 mA hypermethylation promotes melanoma cancer cell metastasis via the WNT/β-catenin pathway. Annals of Translational Medicine. 9: 1155. PMID 34430596 DOI: 10.21037/atm-21-2906  0.238
2007 Pan L, Wu H, Shen C, Shi Y, Jin W, Xia J, Zhang M. Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes. The Embo Journal. 26: 4576-87. PMID 17914463 DOI: 10.1038/Sj.Emboj.7601860  0.238
2011 Liu XQ, Wu H, Yu HL, Zhao TF, Pan YZ, Shi RJ. Purification of a lectin from Arisaema erubescens (Wall.) Schott and its pro-inflammatory effects. Molecules (Basel, Switzerland). 16: 9480-94. PMID 22083235 DOI: 10.3390/molecules16119480  0.237
2019 Wu H, Ting JM, Weiss TM, Tirrell MV. Interparticle Interactions in Dilute Solutions of Polyelectrolyte Complex Micelles. Acs Macro Letters. 8: 819-825. PMID 35619501 DOI: 10.1021/acsmacrolett.9b00226  0.237
2020 Hatcher JM, Yang G, Wang L, Ficarro SB, Buhrlage S, Wu H, Marto JA, Treon SP, Gray NS. Discovery of a Selective, Covalent IRAK1 Inhibitor with Antiproliferative Activity in MYD88 Mutated B-Cell Lymphoma. Acs Medicinal Chemistry Letters. 11: 2238-2243. PMID 33214835 DOI: 10.1021/acsmedchemlett.0c00378  0.237
2023 He R, Chen H, Wu H, Liu J, Chen W, Zhang M, Chen W, Zhong Q. Proteomics reveals energy limitation and amino acid consumption as antibacterial mechanism of linalool against and its application in fresh beef preservation. Food Chemistry: X. 19: 100837. PMID 37780265 DOI: 10.1016/j.fochx.2023.100837  0.237
2016 Wang XZ, Cheng Y, Wang KL, Liu R, Yang XL, Wen HM, Chai C, Liang JY, Wu H. Peperomin E reactivates silenced tumor suppressor genes in lung cancer cells via inhibition of DNA methyltransferase. Cancer Science. PMID 27501331 DOI: 10.1111/cas.13029  0.237
2014 Wan L, Lu X, Yuan S, Wei Y, Guo F, Shen M, Yuan M, Chakrabarti R, Hua Y, Smith HA, Blanco MA, Chekmareva M, Wu H, Bronson RT, Haffty BG, et al. MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors. Cancer Cell. 26: 92-105. PMID 24981741 DOI: 10.1016/J.Ccr.2014.04.027  0.237
2023 Zhu Q, Zhou Y, Wang H, Cao T, Wang X, Liu R, Wu H, Lin B. Fucoxanthin triggers ferroptosis in glioblastoma cells by stabilizing the transferrin receptor. Medical Oncology (Northwood, London, England). 40: 230. PMID 37421513 DOI: 10.1007/s12032-023-02095-6  0.237
2023 Yang N, Guo J, Wu H, Gao M, Xu S. Eucalyptol ameliorates chlorpyrifos-induced necroptosis in grass carp liver cells by down-regulating ROS/NF-κB pathway. Pesticide Biochemistry and Physiology. 198: 105726. PMID 38225081 DOI: 10.1016/j.pestbp.2023.105726  0.237
2021 Vora SM, Lieberman J, Wu H. Inflammasome activation at the crux of severe COVID-19. Nature Reviews. Immunology. PMID 34373622 DOI: 10.1038/s41577-021-00588-x  0.237
2021 Jiao B, Wang M, Feng H, Bao H, Zhang F, Wu H, Wang J, Tang B, Jin P, Shen L. Downregulation of TOP2 modulates neurodegeneration caused by GGGGCC expanded repeats. Human Molecular Genetics. PMID 33749734 DOI: 10.1093/hmg/ddab079  0.237
2021 Yang ZJ, Wang Q, Wu H, Hu J, Fu H, Qu Y, Yang Y, Cai Q, Efimov A, Wu M, Yen T, Wang Y. Nestin is required for spindle assembly and cell cycle progression in glioblastoma cells. Molecular Cancer Research : McR. PMID 34158391 DOI: 10.1158/1541-7786.MCR-20-0994  0.237
2021 Yang ZJ, Wang Q, Wu H, Hu J, Fu H, Qu Y, Yang Y, Cai Q, Efimov A, Wu M, Yen T, Wang Y. Nestin is required for spindle assembly and cell cycle progression in glioblastoma cells. Molecular Cancer Research : McR. PMID 34158391 DOI: 10.1158/1541-7786.MCR-20-0994  0.237
2022 Yu Z, Wu H, Wang Y. Phoenixin-14 Promotes the Recovery of Neurological Dysfunction After Spinal Cord Injury by Regulating Microglial Polarization PTEN/Akt Signaling Pathway. Human & Experimental Toxicology. 41: 9603271221111345. PMID 35968813 DOI: 10.1177/09603271221111345  0.237
2013 Xu GL, Du YF, Cheng J, Huan L, Chen SC, Wei SH, Gong ZN, Cai J, Qiu T, Wu H, Sun T, Ao GZ. Inhibition of inflammatory mediators contributes to the anti-inflammatory activity of KYKZL-1 via MAPK and NF-κB pathway. Toxicology and Applied Pharmacology. 272: 221-9. PMID 23732080 DOI: 10.1016/j.taap.2013.05.025  0.236
2015 Yu HL, Mao SH, Zhao TF, Wu H, Pan YZ, Shu CY. [Antagonistic effect of gingerols against TNF-α release, ROS overproduction and RIP3 expression increase induced by lectin from Pinellia ternata]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 40: 3630-5. PMID 26983212  0.236
2018 Yang W, Wu H, Wang Z, Sun Q, Qiao L, Huang B. The APSES Gene Regulates Sporulation in . Frontiers in Microbiology. 9: 1208. PMID 29922271 DOI: 10.3389/fmicb.2018.01208  0.236
2024 Zhao H, Wu H, Guseman A, Abeykoon D, Camara CM, Dalal Y, Fushman D, Papoian GA. The role of cryptic ancestral symmetry in histone folding mechanisms across Eukarya and Archaea. Plos Computational Biology. 20: e1011721. PMID 38181064 DOI: 10.1371/journal.pcbi.1011721  0.236
2021 Song HH, Song TC, Yang T, Sun CS, He BQ, Li H, Wang YJ, Li Y, Wu H, Hu YM, Wang YJ. High mobility group box 1 mediates inflammatory response of astrocytes via cyclooxygenase 2/prostaglandin E2 signaling following spinal cord injury. Neural Regeneration Research. 16: 1848-1855. PMID 33510092 DOI: 10.4103/1673-5374.303039  0.236
2014 Wang Y, Zhang Z, Guo W, Sun W, Miao X, Wu H, Cong X, Wintergerst KA, Kong X, Cai L. Sulforaphane reduction of testicular apoptotic cell death in diabetic mice is associated with the upregulation of Nrf2 expression and function. American Journal of Physiology. Endocrinology and Metabolism. 307: E14-23. PMID 24801392 DOI: 10.1152/ajpendo.00702.2013  0.236
2003 Wu H, Wang ZX. The mechanism of p21-activated kinase 2 autoactivation. The Journal of Biological Chemistry. 278: 41768-78. PMID 12907671 DOI: 10.1074/jbc.M308196200  0.236
2021 Wu H, Tong Y, Zhou R, Wang Y, Wang Z, Ding T, Huang B. Mr-AbaA Regulates Conidiation by Interacting with the Promoter Regions of Both and in Metarhizium robertsii. Microbiology Spectrum. e0082321. PMID 34494863 DOI: 10.1128/Spectrum.00823-21  0.236
2017 Li X, Chen H, Xue L, Pang X, Zhang X, Zhu Z, Zhu W, Wang Z, Wu H. p53 performs an essential role in mediating the oncogenic stimulus triggered by loss of expression of neurofibromatosis type 2 during in vitro tumor progression. Oncology Letters. 14: 2223-2231. PMID 28789444 DOI: 10.3892/ol.2017.6445  0.236
2022 Bo C, Cai R, Fang X, Wu H, Ma Z, Yuan H, Cheng B, Fan J, Ma Q. Transcription factor ZmWRKY20 interacts with ZmWRKY115 to repress expression of ZmbZIP111 for salt tolerance in maize. The Plant Journal : For Cell and Molecular Biology. PMID 35861696 DOI: 10.1111/tpj.15914  0.236
2023 Sen Santara S, Lee DJ, Crespo Â, Hu JJ, Walker C, Ma X, Zhang Y, Chowdhury S, Meza-Sosa KF, Lewandrowski M, Zhang H, Rowe M, McClelland A, Wu H, Junqueira C, et al. The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells. Nature. PMID 37020026 DOI: 10.1038/s41586-023-05912-0  0.236
2020 Wu H, Wang Y, Zhang Y, Xu F, Chen J, Duan L, Zhang T, Wang J, Zhang F. Breaking the vicious loop between inflammation, oxidative stress and coagulation, a novel anti-thrombus insight of nattokinase by inhibiting LPS-induced inflammation and oxidative stress. Redox Biology. 32: 101500. PMID 32193146 DOI: 10.1016/j.redox.2020.101500  0.236
2016 Wu H, Fuxreiter M. The Structure and Dynamics of Higher-Order Assemblies: Amyloids, Signalosomes, and Granules. Cell. 165: 1055-1066. PMID 27203110 DOI: 10.1016/j.cell.2016.05.004  0.236
2022 Xie WJ, Xia S, Warshel A, Wu H. Electrostatic influence on IL-1 transport through the GSDMD pore. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35115408 DOI: 10.1073/pnas.2120287119  0.236
2021 Song J, Wu H, He F, Qu J, Wang Y, Li C, Liu JH. Citrus sinensis CBF1 Functions in Cold Tolerance by Modulating Putrescine Biosynthesis Through Regulation of ARGININE DECARBOXYLASE. Plant & Cell Physiology. PMID 34478552 DOI: 10.1093/pcp/pcab135  0.236
2019 Li G, Tian X, Lv D, Zhang L, Zhang Z, Wang J, Yang M, Tao J, Ma T, Wu H, Ji P, Wu Y, Lian Z, Cui W, Liu G. NLRP7 is expressed in ovine ovary and associated with in vitro preimplantation embryo development. Reproduction (Cambridge, England). PMID 31505467 DOI: 10.1530/REP-19-0081  0.236
2022 Huang P, Zhao J, Fowdur M, Liu Y, Wu H, He M. Knockdown of RPL34 suppresses osteosarcoma cell proliferation likely through EIF3/FAU signaling pathway. Translational Cancer Research. 8: 848-855. PMID 35116824 DOI: 10.21037/tcr.2019.05.05  0.236
2022 Ying L, Wu H, Zhou S, Lu H, Ding M, Wang B, Wang S, Mao Y, Xiao F, Li Y. Toll-Like Receptors Signaling Pathway of Quercetin Regulating Avian Beta-Defensin in the Ileum of Broilers. Frontiers in Cell and Developmental Biology. 10: 816771. PMID 35281079 DOI: 10.3389/fcell.2022.816771  0.236
2020 Tong Y, Wu H, Liu Z, Wang Z, Huang B. G-Protein Subunit Gα in Mitochondria, MrGPA1, Affects Conidiation, Stress Resistance, and Virulence of Entomopathogenic Fungus . Frontiers in Microbiology. 11: 1251. PMID 32612588 DOI: 10.3389/fmicb.2020.01251  0.235
2023 Man YN, Sun Y, Chen PJ, Wu H, He ML. TAF1D Functions as a Novel Biomarker in Osteosarcoma. Journal of Cancer. 14: 2051-2065. PMID 37497412 DOI: 10.7150/jca.85688  0.235
2022 Zhang J, Li S, Zhang J, Zhang W, Jiang J, Wu H, Wu E, Feng Y, Yang L, Li Z. Docetaxel resistance-derived LINC01085 contributes to the immunotherapy of hormone-independent prostate cancer by activating the STING/MAVS signaling pathway. Cancer Letters. 545: 215829. PMID 35868534 DOI: 10.1016/j.canlet.2022.215829  0.235
2021 Hu C, Liu H, Pang B, Wu H, Lin X, Zhen Y, Yi H. Supraphysiological estradiol promotes human T follicular helper cell differentiation and favours humoural immunity during in vitro fertilization. Journal of Cellular and Molecular Medicine. PMID 34032001 DOI: 10.1111/jcmm.16651  0.235
2022 Wang J, Yu C, Zhuang J, Qi W, Jiang J, Liu X, Zhao W, Cao Y, Wu H, Qi J, Zhao RC. The role of phosphatidylserine on the membrane in immunity and blood coagulation. Biomarker Research. 10: 4. PMID 35033201 DOI: 10.1186/s40364-021-00346-0  0.235
2012 Nie YC, Wu H, Li PB, Xie LM, Luo YL, Shen JG, Su WW. Naringin attenuates EGF-induced MUC5AC secretion in A549 cells by suppressing the cooperative activities of MAPKs-AP-1 and IKKs-IκB-NF-κB signaling pathways. European Journal of Pharmacology. 690: 207-13. PMID 22766066 DOI: 10.1016/j.ejphar.2012.06.040  0.235
2017 Wu H, Wang J, Ma H, Xiao Z, Dong X. MicroRNA-21 inhibits mitochondria-mediated apoptosis in keloid. Oncotarget. 8: 92914-92925. PMID 29190966 DOI: 10.18632/oncotarget.21656  0.235
2022 Wang G, Guo Z, Zhang X, Wu H, Bai X, Zhang H, Hu R, Han S, Pang Y, Gao Z, Yan L, Huang C, Zhang L, Pan C, Liu X. Heterologous expression of pediocin/papA in Bacillus subtilis. Microbial Cell Factories. 21: 104. PMID 35643507 DOI: 10.1186/s12934-022-01829-x  0.235
2013 He J, Shen L, Wan M, Taranova O, Wu H, Zhang Y. Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes. Nature Cell Biology. 15: 373-84. PMID 23502314 DOI: 10.1038/Ncb2702  0.235
2016 Wu H, Zhou J, Zeng C, Wu D, Mu Z, Chen B, Xie Y, Ye Y, Liu J. Curcumin increases exosomal TCF21 thus suppressing exosome-induced lung cancer. Oncotarget. PMID 27894084 DOI: 10.18632/oncotarget.13499  0.235
2019 Wang J, Liu J, Sun G, Meng H, Wang J, Guan Y, Yin Y, Zhao Z, Dong X, Yin S, Li H, Cheng Y, Wu H, Wu A, Yu X, et al. Glioblastoma extracellular vesicles induce the tumour-promoting transformation of neural stem cells. Cancer Letters. PMID 31521694 DOI: 10.1016/J.Canlet.2019.09.004  0.235
2019 Wu H, Yang K, Zhang Z, Leisten E, Li Z, Xie H, Liu J, Smith KA, Novakova Z, Barinka C, Tang W. Development of Multi-Functional Histone Deacetylase 6 Degraders with Potent Anti-Myeloma Activity. Journal of Medicinal Chemistry. PMID 31271281 DOI: 10.1021/Acs.Jmedchem.9B00516  0.235
2020 Yang K, Wu H, Zhang Z, Leisten ED, Nie X, Liu B, Wen Z, Zhang J, Cunningham MD, Tang W. Development of Selective Histone Deacetylase 6 (HDAC6) Degraders Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. Acs Medicinal Chemistry Letters. 11: 575-581. PMID 32292566 DOI: 10.1021/Acsmedchemlett.0C00046  0.235
2017 Wang J, Gu J, Wu H, Zhu G, Feng D, Li Y, Guo W, Tian K, Gao G, Gao L. Pentazocine Protects SN4741 Cells Against MPP(+)-Induced Cell Damage via Up-Regulation of the Canonical Wnt/β-Catenin Signaling Pathway. Frontiers in Aging Neuroscience. 9: 196. PMID 28659791 DOI: 10.3389/fnagi.2017.00196  0.235
2020 Hu J, Yang Z, Wu H, Wang D. Rhein attenuates renal inflammatory injury of uric acid nephropathy via lincRNA-Cox2/miR-150-5p/STAT1 axis. International Immunopharmacology. 85: 106620. PMID 32504995 DOI: 10.1016/j.intimp.2020.106620  0.235
2020 Zuo Y, Yin L, Cheng X, Li J, Wu H, Liu X, Gu E, Wu J. Elamipretide Attenuates Pyroptosis and Perioperative Neurocognitive Disorders in Aged Mice. Frontiers in Cellular Neuroscience. 14: 251. PMID 32903868 DOI: 10.3389/fncel.2020.00251  0.234
2022 Miao Z, Miao Z, Shi X, Wu H, Yao Y, Xu S. The antagonistic effect of selenium on lead-induced apoptosis and necroptosis via P38/JNK/ERK pathway in chicken kidney. Ecotoxicology and Environmental Safety. 231: 113176. PMID 35026588 DOI: 10.1016/j.ecoenv.2022.113176  0.234
2022 Meza-Sosa KF, Miao R, Navarro F, Zhang Z, Zhang Y, Hu JJ, Hartford CCR, Li XL, Pedraza-Alva G, Pérez-Martínez L, Lal A, Wu H, Lieberman J. SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage. Molecular Cell. PMID 35104452 DOI: 10.1016/j.molcel.2022.01.001  0.234
2018 Li Y, Xue Y, Xu X, Wang G, Liu Y, Wu H, Li W, Wang Y, Chen Z, Zhang W, Zhu Y, Ji W, Xu T, Liu L, Chen Q. A mitochondrial FUNDC1/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity. The Embo Journal. PMID 30591555 DOI: 10.15252/embj.201798786  0.234
2023 Wang K, Tang J, Fan S, Su H, Yu R, Zhang Y, Wu H, Lv Y, Zhang S, Zou X. ABBV-744 induces autophagy in gastric cancer cells by regulating PI3K/AKT/mTOR/p70S6k and MAPK signaling pathways. Neoplasia (New York, N.Y.). 45: 100936. PMID 37769529 DOI: 10.1016/j.neo.2023.100936  0.234
2022 Zhang Y, Wu J, Fu Y, Yu R, Su H, Zheng Q, Wu H, Zhou S, Wang K, Zhao J, Shen S, Xu G, Wang L, Yan C, Zou X, et al. Hesperadin suppresses pancreatic cancer through ATF4/GADD45A axis at nanomolar concentrations. Oncogene. PMID 35551503 DOI: 10.1038/s41388-022-02328-4  0.234
2022 Wu W, Liu S, Wu H, Chen M, Gao L, Zhao B, Liu B, Pang Q. DjPtpn11 is an essential modulator of planarian (Dugesia japonica) regeneration. International Journal of Biological Macromolecules. PMID 35452697 DOI: 10.1016/j.ijbiomac.2022.04.095  0.234
2016 Jin YP, Wu H, Yu HL, Pan YZ, Chen YQ, Wang KL, Zhang CC, Wang W. [Antagonism mechanism of gingerols against inflammatory effect of toxic raphides from Pinella pedatisecta]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 41: 1087-1092. PMID 28875675  0.234
2022 Zhou W, Sun J, Huai C, Liu Y, Chen L, Yi Z, Lv Q, Song C, Zhu W, Liu C, Weng S, Wu H, Sun Y, Zhang R, Wu L, et al. Multi-omics analysis identifies rare variation in leptin/PPAR gene sets and hypermethylation of ABCG1 contribute to antipsychotics-induced metabolic syndromes. Molecular Psychiatry. PMID 36065016 DOI: 10.1038/s41380-022-01759-5  0.234
2022 Miao S, Zhou J, Liu B, Lei X, Wang T, Hao X, Cheng P, Wu H, Song Y, Pei G, Bi L. A 3D bioprinted nano-laponite hydrogel construct promotes osteogenesis by activating PI3K/AKT signaling pathway. Materials Today. Bio. 16: 100342. PMID 35847377 DOI: 10.1016/j.mtbio.2022.100342  0.234
2022 Ma W, Wu H, Li G, Yan L, Wang L, Zhao M, Guan S, Xu S, Guo X, Liu F, Ji P, Wusiman A, Liu G. Melatonin promotes the growth and development of lambs by increasing growth hormone and testosterone, targeting on apoptosis signaling pathway and intestinal microflora. Frontiers in Endocrinology. 13: 966120. PMID 36060949 DOI: 10.3389/fendo.2022.966120  0.234
2021 Wu H, Zhang Z, Xiao XY, Zhang ZY, Gao SL, Lu C, Zuo L, Zhang LF. Toll-like receptor 2 (TLR2) is a candidate prognostic factor in testicular germ cell tumors as well as an indicator of immune function in the tumor microenvironment. Bioengineered. 12: 1939-1951. PMID 34002664 DOI: 10.1080/21655979.2021.1927560  0.234
2019 Mompeán M, Bozkurt G, Wu H. Mimicry by a viral RHIM. Embo Reports. PMID 30665943 DOI: 10.15252/embr.201847433  0.234
2019 Wu H, Reimann S, Siddiqui S, Haag R, Siegmund B, Dernedde J, Glauben R. dPGS Regulates the Phenotype of Macrophages via Metabolic Switching. Macromolecular Bioscience. e1900184. PMID 31631571 DOI: 10.1002/Mabi.201900184  0.234
2018 Huang ZQ, Chen P, Su WW, Wang YG, Wu H, Peng W, Li PB. Antioxidant Activity and Hepatoprotective Potential of Quercetin 7-Rhamnoside In Vitro and In Vivo. Molecules (Basel, Switzerland). 23. PMID 29772655 DOI: 10.3390/molecules23051188  0.234
2022 Sun X, Sun X, Meng H, Wu J, Guo X, Du L, Wu H. Krill Oil Inhibits NLRP3 Inflammasome Activation in the Prevention of the Pathological Injuries of Diabetic Cardiomyopathy. Nutrients. 14. PMID 35057549 DOI: 10.3390/nu14020368  0.234
2023 Wang S, Liu Y, Sun Q, Zeng B, Liu C, Gong L, Wu H, Chen L, Jin M, Guo J, Gao Z, Huang W. Triple Cross-linked Dynamic Responsive Hydrogel Loaded with Selenium Nanoparticles for Modulating the Inflammatory Microenvironment via PI3K/Akt/NF-κB and MAPK Signaling Pathways. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2303167. PMID 37740428 DOI: 10.1002/advs.202303167  0.234
2017 Chen B, Zeng C, Ye Y, Wu D, Mu Z, Liu J, Xie Y, Wu H. Promoter methylation of TCF21 may repress autophagy in the progression of lung cancer. Journal of Cell Communication and Signaling. PMID 29086202 DOI: 10.1007/s12079-017-0418-2  0.234
2020 Liu J, Zhang C, Wu H, Sun XX, Li Y, Huang S, Yue X, Lu SE, Shen Z, Su X, White E, Haffty BG, Hu W, Feng Z. Parkin ubiquitinates phosphoglycerate dehydrogenase to suppress serine synthesis and tumor progression. The Journal of Clinical Investigation. 130: 3253-3269. PMID 32478681 DOI: 10.1172/Jci132876  0.234
2015 Best-Rocha A, Patel KR, Hicks J, Edmonds JL, Paldino MJ, Wu H. Novel association of odontogenic myxoma with constitutional chromosomal 1q21 microduplication: case report and review of the literature. Pediatric and Developmental Pathology : the Official Journal of the Society For Pediatric Pathology and the Paediatric Pathology Society. PMID 26230961 DOI: 10.2350/15-05-1637-CR.1  0.233
2021 Wang Z, Chen H, Xue L, He W, Shu W, Wu H, Wang Z. High throughput proteomic and metabolic profiling identified target correction of metabolic abnormalities as a novel therapeutic approach in head and neck paraganglioma. Translational Oncology. 14: 101146. PMID 34118692 DOI: 10.1016/j.tranon.2021.101146  0.233
2017 Sun C, Fu Z, Wang S, Li J, Li Y, Zhang Y, Yang F, Chu J, Wu H, Huang X, Li W, Yin Y. Roles of tRNA-derived fragments in human cancers. Cancer Letters. PMID 29107107 DOI: 10.1016/j.canlet.2017.10.031  0.233
2022 Zhang X, Li M, Wu H, Fan W, Zhang J, Su W, Wang Y, Li P. Naringenin attenuates inflammation, apoptosis, and ferroptosis in silver nanoparticle-induced lung injury through a mechanism associated with Nrf2/HO-1 axis: In vitro and in vivo studies. Life Sciences. 311: 121127. PMID 36306867 DOI: 10.1016/j.lfs.2022.121127  0.233
2018 Xu W, Fu J, Wu H, Sun W. Human epidermal growth factor receptor 2 expressions and Janus-activated kinase/signal transducer and activator of transcription 3-suppressor of cytokine signaling 3 pathway may be associated with clinicopathological features and prognosis of gastric cancer. Journal of Cancer Research and Therapeutics. 14: S311-S318. PMID 29970682 DOI: 10.4103/0973-1482.235348  0.233
2016 Xu X, Meng Q, Erben U, Wang P, Glauben R, Kühl AA, Wu H, Ma CW, Hu M, Wang Y, Sun W, Jia J, Wu X, Chen W, Siegmund B, et al. Myeloid-derived suppressor cells promote B-cell production of IgA in a TNFR2-dependent manner. Cellular & Molecular Immunology. PMID 27133471 DOI: 10.1038/cmi.2015.103  0.233
2014 Xu J, Zeng F, Wu H, Hu C, Wu S. Enhanced photodynamic efficiency achieved via a dual-targeted strategy based on photosensitizer/micelle structure. Biomacromolecules. 15: 4249-59. PMID 25329523 DOI: 10.1021/bm501270e  0.233
2023 Han Y, Hu A, Qu Y, Xu Q, Wang H, Feng Y, Hu Y, He L, Wu H, Wang X. Covalent targeting the LAS1-NOL9 axis for selective treatment in NPM1 mutant acute myeloid leukemia. Pharmacological Research. 106700. PMID 36796466 DOI: 10.1016/j.phrs.2023.106700  0.233
2022 Wu H, Gao J, Xie M, Xiang J, Zuo Z, Tian X, Song R, Yuan X, Wu Y, Ou D. Histopathology and transcriptome analysis reveals the gills injury and immunotoxicity in gibel carp following acute deltamethrin exposure. Ecotoxicology and Environmental Safety. 234: 113421. PMID 35304335 DOI: 10.1016/j.ecoenv.2022.113421  0.233
2020 Wu J, Sun X, Jiang Z, Jiang J, Xu L, Tian A, Sun X, Meng H, Li Y, Huang W, Jia Y, Wu H. Protective role of NRF2 in macrovascular complications of diabetes. Journal of Cellular and Molecular Medicine. PMID 32628815 DOI: 10.1111/jcmm.15583  0.233
2023 Wu H, Zhao X, Hochrein SM, Eckstein M, Gubert GF, Knöpper K, Mansilla AM, Öner A, Doucet-Ladevèze R, Schmitz W, Ghesquière B, Theurich S, Dudek J, Gasteiger G, Zernecke A, et al. Mitochondrial dysfunction promotes the transition of precursor to terminally exhausted T cells through HIF-1α-mediated glycolytic reprogramming. Nature Communications. 14: 6858. PMID 37891230 DOI: 10.1038/s41467-023-42634-3  0.233
2020 Rong N, Zhang M, Wang Y, Wu H, Qi H, Fu X, Li D, Yang C, Wang Y, Fan Z. Effects of extracellular matrix rigidity on sonoporation facilitated by targeted microbubbles: Bubble attachment, bubble dynamics, and cell membrane permeabilization. Ultrasonics Sonochemistry. 67: 105125. PMID 32298974 DOI: 10.1016/J.Ultsonch.2020.105125  0.233
2011 Wu H, Siegel RM. Medicine. Progranulin resolves inflammation. Science (New York, N.Y.). 332: 427-8. PMID 21512023 DOI: 10.1126/science.1205992  0.233
2014 Wu H, Mitra M, Naufer MN, McCauley MJ, Gorelick RJ, Rouzina I, Musier-Forsyth K, Williams MC. Differential contribution of basic residues to HIV-1 nucleocapsid protein's nucleic acid chaperone function and retroviral replication. Nucleic Acids Research. 42: 2525-37. PMID 24293648 DOI: 10.1093/Nar/Gkt1227  0.232
2022 Yu W, Tu Y, Long Z, Liu J, Kong D, Peng J, Wu H, Zheng G, Zhao J, Chen Y, Liu R, Li W, Hai C. Reactive Oxygen Species Bridge the Gap between Chronic Inflammation and Tumor Development. Oxidative Medicine and Cellular Longevity. 2022: 2606928. PMID 35799889 DOI: 10.1155/2022/2606928  0.232
2008 Wu H, Li W, Wang T, Shu Y, Liu P. Paeoniflorin suppress NF-kappaB activation through modulation of I kappaB alpha and enhances 5-fluorouracil-induced apoptosis in human gastric carcinoma cells. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 62: 659-66. PMID 18809274 DOI: 10.1016/j.biopha.2008.08.002  0.232
2018 Xu X, Wang M, Li JZ, Wei SD, Wu H, Lai X, Cao D, Ou ZB, Gong J. Tauroursodeoxycholic acid alleviates hepatic ischemia reperfusion injury by suppressing the function of Kupffer cells in mice. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 106: 1271-1281. PMID 30119197 DOI: 10.1016/j.biopha.2018.06.046  0.232
2020 Fu J, Chen X, Liu X, Xu D, Yang H, Zeng C, Long H, Zhou C, Wu H, Zheng G, Wu H, Wang W, Wang T. ELABELA ameliorates hypoxic/ischemic-induced bone mesenchymal stem cell apoptosis via alleviation of mitochondrial dysfunction and activation of PI3K/AKT and ERK1/2 pathways. Stem Cell Research & Therapy. 11: 541. PMID 33317626 DOI: 10.1186/s13287-020-02063-1  0.232
2023 Liu Q, Wang F, Chen Y, Cui H, Wu H. A regulatory module comprising G3BP1-FBXL5-IRP2 axis determines sodium arsenite-induced ferroptosis. Journal of Hazardous Materials. 465: 133038. PMID 38118197 DOI: 10.1016/j.jhazmat.2023.133038  0.232
2019 Liu J, Wu H, Huang C, Lei D, Zhang M, Xie W, Li J, Ren G. Optimized Negative-Staining Protocol for Lipid-Protein Interactions Investigated by Electron Microscopy. Methods in Molecular Biology (Clifton, N.J.). 2003: 163-173. PMID 31218618 DOI: 10.1007/978-1-4939-9512-7_8  0.232
2018 Sun G, Fang X, Wu H, Zhou X, Ke Y, Sun T. Porcine monocyte-derived dendritic cells can be differentially activated by vesicular stomatitis virus and its matrix protein mutants. Veterinary Microbiology. 219: 30-39. PMID 29778202 DOI: 10.1016/j.vetmic.2018.04.011  0.232
2020 Wu R, Li L, Bai Y, Yu B, Xie C, Wu H, Zhang Y, Huang L, Yan Y, Li X, Lin C. The long noncoding RNA LUCAT1 promotes colorectal cancer cell proliferation by antagonizing Nucleolin to regulate MYC expression. Cell Death & Disease. 11: 908. PMID 33097685 DOI: 10.1038/s41419-020-03095-4  0.232
2023 Sun C, Huang X, Li J, Fu Z, Hua Y, Zeng T, He Y, Duan N, Yang F, Liang Y, Wu H, Li W, Zhang Y, Yin Y. Exosome-Transmitted tRF-16-K8J7K1B Promotes Tamoxifen Resistance by Reducing Drug-Induced Cell Apoptosis in Breast Cancer. Cancers. 15. PMID 36765853 DOI: 10.3390/cancers15030899  0.232
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