Ardem Patapoutian - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 

98 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Song Y, Li D, Farrelly O, Miles L, Li F, Kim SE, Lo TY, Wang F, Li T, Thompson-Peer KL, Gong J, Murthy SE, Coste B, Yakubovich N, Patapoutian A, et al. The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration. Neuron. PMID 30819546 DOI: 10.1016/j.neuron.2019.01.050  0.76
2018 Nonomura K, Lukacs V, Sweet DT, Goddard LM, Kanie A, Whitwam T, Ranade SS, Fujimori T, Kahn ML, Patapoutian A. Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation. Proceedings of the National Academy of Sciences of the United States of America. 115: 12817-12822. PMID 30482854 DOI: 10.1073/pnas.1817070115  0.52
2018 Hoffman BU, Baba Y, Griffith TN, Mosharov EV, Woo SH, Roybal DD, Karsenty G, Patapoutian A, Sulzer D, Lumpkin EA. Merkel Cells Activate Sensory Neural Pathways through Adrenergic Synapses. Neuron. PMID 30415995 DOI: 10.1016/j.neuron.2018.10.034  0.6
2018 Jojoa Cruz S, Saotome K, Murthy SE, Tsui CCA, Sansom MS, Patapoutian A, Ward AB. Cryo-EM structure of the mechanically activated ion channel OSCA1.2. Elife. 7. PMID 30382939 DOI: 10.7554/eLife.41845  0.52
2018 Murthy SE, Dubin AE, Whitwam T, Jojoa Cruz S, Cahalan SM, Mosavi SA, Ward AB, Patapoutian A. OSCA/TMEM63 are an evolutionarily conserved family of mechanically activated ion channels. Elife. 7. PMID 30382938 DOI: 10.7554/eLife.41844  0.56
2018 Zeng WZ, Marshall KL, Min S, Daou I, Chapleau MW, Abboud FM, Liberles SD, Patapoutian A. PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex. Science (New York, N.Y.). 362: 464-467. PMID 30361375 DOI: 10.1126/science.aau6324  0.36
2018 Murthy SE, Loud MC, Daou I, Marshall KL, Schwaller F, Kühnemund J, Francisco AG, Keenan WT, Dubin AE, Lewin GR, Patapoutian A. The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice. Science Translational Medicine. 10. PMID 30305457 DOI: 10.1126/scitranslmed.aat9897  0.56
2018 Kefauver JM, Saotome K, Dubin AE, Pallesen J, Cottrell CA, Cahalan SM, Qiu Z, Hong G, Crowley CS, Whitwam T, Lee WH, Ward AB, Patapoutian A. Structure of the human volume regulated anion channel. Elife. 7. PMID 30095067 DOI: 10.7554/eLife.38461  0.56
2018 Xu J, Mathur J, Vessières E, Hammack S, Nonomura K, Favre J, Grimaud L, Petrus M, Francisco A, Li J, Lee V, Xiang FL, Mainquist JK, Cahalan SM, Orth AP, ... ... Patapoutian A, et al. GPR68 Senses Flow and Is Essential for Vascular Physiology. Cell. 173: 762-775.e16. PMID 29677517 DOI: 10.1016/j.cell.2018.03.076  0.48
2018 Ma S, Cahalan S, LaMonte G, Grubaugh ND, Zeng W, Murthy SE, Paytas E, Gamini R, Lukacs V, Whitwam T, Loud M, Lohia R, Berry L, Khan SM, Janse CJ, ... ... Patapoutian A, et al. Common PIEZO1 Allele in African Populations Causes RBC Dehydration and Attenuates Plasmodium Infection. Cell. PMID 29576450 DOI: 10.1016/j.cell.2018.02.047  0.52
2017 Saotome K, Murthy SE, Kefauver JM, Whitwam T, Patapoutian A, Ward AB. Structure of the mechanically activated ion channel Piezo1. Nature. PMID 29261642 DOI: 10.1038/nature25453  0.52
2017 Murthy SE, Dubin AE, Patapoutian A. Piezos thrive under pressure: mechanically activated ion channels in health and disease. Nature Reviews. Molecular Cell Biology. PMID 28974772 DOI: 10.1038/nrm.2017.92  0.56
2017 Dubin AE, Murthy S, Lewis AH, Brosse L, Cahalan SM, Grandl J, Coste B, Patapoutian A. Endogenous Piezo1 Can Confound Mechanically Activated Channel Identification and Characterization. Neuron. 94: 266-270.e3. PMID 28426961 DOI: 10.1016/j.neuron.2017.03.039  0.76
2017 Dubin AE, Murthy S, Lewis AH, Brosse L, Cahalan SM, Grandl J, Coste B, Patapoutian A. Editorial Note to: Endogenous Piezo1 Can Confound Mechanically Activated Channel Identification and Characterization. Neuron. 94: 265. PMID 28426960 DOI: 10.1016/j.neuron.2017.03.041  0.76
2016 Nonomura K, Woo SH, Chang RB, Gillich A, Qiu Z, Francisco AG, Ranade SS, Liberles SD, Patapoutian A. Piezo2 senses airway stretch and mediates lung inflation-induced apnoea. Nature. PMID 28002412 DOI: 10.1038/nature20793  0.6
2016 Wu Z, Grillet N, Zhao B, Cunningham C, Harkins-Perry S, Coste B, Ranade S, Zebarjadi N, Beurg M, Fettiplace R, Patapoutian A, Müller U. Mechanosensory hair cells express two molecularly distinct mechanotransduction channels. Nature Neuroscience. PMID 27893727 DOI: 10.1038/nn.4449  0.4
2016 Syeda R, Florendo MN, Cox CD, Kefauver JM, Santos JS, Martinac B, Patapoutian A. Piezo1 Channels Are Inherently Mechanosensitive. Cell Reports. 17: 1739-1746. PMID 27829145 DOI: 10.1016/j.celrep.2016.10.033  0.52
2016 Syeda R, Qiu Z, Dubin AE, Murthy SE, Florendo MN, Mason DE, Mathur J, Cahalan SM, Peters EC, Montal M, Patapoutian A. LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength. Cell. 164: 499-511. PMID 26824658 DOI: 10.1016/j.cell.2015.12.031  0.92
2015 Woo SH, Lukacs V, de Nooij JC, Zaytseva D, Criddle CR, Francisco A, Jessell TM, Wilkinson KA, Patapoutian A. Piezo2 is the principal mechanotransduction channel for proprioception. Nature Neuroscience. PMID 26551544 DOI: 10.1038/nn.4162  0.92
2015 Ranade SS, Syeda R, Patapoutian A. Mechanically Activated Ion Channels. Neuron. 87: 1162-79. PMID 26402601 DOI: 10.1016/j.neuron.2015.08.032  0.92
2015 Lukacs V, Mathur J, Mao R, Bayrak-Toydemir P, Procter M, Cahalan SM, Kim HJ, Bandell M, Longo N, Day RW, Stevenson DA, Patapoutian A, Krock BL. Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia. Nature Communications. 6: 8329. PMID 26387913 DOI: 10.1038/ncomms9329  0.92
2015 Coste B, Murthy SE, Mathur J, Schmidt M, Mechioukhi Y, Delmas P, Patapoutian A. Piezo1 ion channel pore properties are dictated by C-terminal region. Nature Communications. 6: 7223. PMID 26008989 DOI: 10.1038/ncomms8223  0.92
2015 Syeda R, Xu J, Dubin AE, Coste B, Mathur J, Huynh T, Matzen J, Lao J, Tully DC, Engels IH, Petrassi HM, Schumacher AM, Montal M, Bandell M, Patapoutian A. Chemical activation of the mechanotransduction channel Piezo1. Elife. 4. PMID 26001275 DOI: 10.7554/eLife.07369  0.92
2015 Cahalan SM, Lukacs V, Ranade SS, Chien S, Bandell M, Patapoutian A. Piezo1 links mechanical forces to red blood cell volume. Elife. 4. PMID 26001274 DOI: 10.7554/eLife.07370  0.92
2015 Wieskopf JS, Mathur J, Limapichat W, Post MR, Al-Qazzaz M, Sorge RE, Martin LJ, Zaykin DV, Smith SB, Freitas K, Austin JS, Dai F, Zhang J, Marcovitz J, Tuttle AH, ... ... Patapoutian A, et al. The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors. Science Translational Medicine. 7: 287ra72. PMID 25972004 DOI: 10.1126/scitranslmed.3009986  0.92
2015 Woo SH, Lumpkin EA, Patapoutian A. Merkel cells and neurons keep in touch. Trends in Cell Biology. 25: 74-81. PMID 25480024 DOI: 10.1016/j.tcb.2014.10.003  0.92
2014 Ranade SS, Woo SH, Dubin AE, Moshourab RA, Wetzel C, Petrus M, Mathur J, Bégay V, Coste B, Mainquist J, Wilson AJ, Francisco AG, Reddy K, Qiu Z, Wood JN, ... ... Patapoutian A, et al. Piezo2 is the major transducer of mechanical forces for touch sensation in mice. Nature. 516: 121-5. PMID 25471886 DOI: 10.1038/nature13980  0.92
2014 Ranade SS, Qiu Z, Woo SH, Hur SS, Murthy SE, Cahalan SM, Xu J, Mathur J, Bandell M, Coste B, Li YS, Chien S, Patapoutian A. Piezo1, a mechanically activated ion channel, is required for vascular development in mice. Proceedings of the National Academy of Sciences of the United States of America. 111: 10347-52. PMID 24958852 DOI: 10.1073/pnas.1409233111  0.92
2014 Rooney L, Vidal A, D'Souza AM, Devereux N, Masick B, Boissel V, West R, Head V, Stringer R, Lao J, Petrus MJ, Patapoutian A, Nash M, Stoakley N, Panesar M, et al. Discovery, optimization, and biological evaluation of 5-(2-(trifluoromethyl)phenyl)indazoles as a novel class of transient receptor potential A1 (TRPA1) antagonists. Journal of Medicinal Chemistry. 57: 5129-40. PMID 24884675 DOI: 10.1021/jm401986p  0.92
2014 Jabba S, Goyal R, Sosa-Pagán JO, Moldenhauer H, Wu J, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. Directionality of temperature activation in mouse TRPA1 ion channel can be inverted by single-point mutations in ankyrin repeat six. Neuron. 82: 1017-31. PMID 24814535 DOI: 10.1016/j.neuron.2014.04.016  0.92
2014 Qiu Z, Dubin AE, Mathur J, Tu B, Reddy K, Miraglia LJ, Reinhardt J, Orth AP, Patapoutian A. SWELL1, a plasma membrane protein, is an essential component of volume-regulated anion channel. Cell. 157: 447-58. PMID 24725410 DOI: 10.1016/j.cell.2014.03.024  0.92
2014 Woo SH, Ranade S, Weyer AD, Dubin AE, Baba Y, Qiu Z, Petrus M, Miyamoto T, Reddy K, Lumpkin EA, Stucky CL, Patapoutian A. Piezo2 is required for Merkel-cell mechanotransduction. Nature. 509: 622-6. PMID 24717433 DOI: 10.1038/nature13251  0.92
2014 Maksimovic S, Nakatani M, Baba Y, Nelson AM, Marshall KL, Wellnitz SA, Firozi P, Woo SH, Ranade S, Patapoutian A, Lumpkin EA. Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors. Nature. 509: 617-21. PMID 24717432 DOI: 10.1038/nature13250  0.92
2013 Albuisson J, Murthy SE, Bandell M, Coste B, Louis-Dit-Picard H, Mathur J, Fénéant-Thibault M, Tertian G, de Jaureguiberry JP, Syfuss PY, Cahalan S, Garçon L, Toutain F, Simon Rohrlich P, Delaunay J, ... ... Patapoutian A, et al. Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels. Nature Communications. 4: 1884. PMID 23695678 DOI: 10.1038/ncomms2899  0.92
2013 Kim SE, Patapoutian A, Grandl J. Single residues in the outer pore of TRPV1 and TRPV3 have temperature-dependent conformations. Plos One. 8: e59593. PMID 23555720 DOI: 10.1371/journal.pone.0059593  0.92
2013 Coste B, Houge G, Murray MF, Stitziel N, Bandell M, Giovanni MA, Philippakis A, Hoischen A, Riemer G, Steen U, Steen VM, Mathur J, Cox J, Lebo M, Rehm H, ... ... Patapoutian A, et al. Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis. Proceedings of the National Academy of Sciences of the United States of America. 110: 4667-72. PMID 23487782 DOI: 10.1073/pnas.1221400110  0.92
2013 Coste B, Patapoutian A. Neuroscience: Salty sensations. Nature. 494: 44-5. PMID 23364688 DOI: 10.1038/nature11946  0.92
2012 Dubin AE, Schmidt M, Mathur J, Petrus MJ, Xiao B, Coste B, Patapoutian A. Inflammatory signals enhance piezo2-mediated mechanosensitive currents. Cell Reports. 2: 511-7. PMID 22921401 DOI: 10.1016/j.celrep.2012.07.014  0.92
2012 Bandell M, Patapoutian A. A hot new channel. Nature Neuroscience. 15: 931-3. PMID 22735512 DOI: 10.1038/nn.3148  0.92
2012 Coste B, Xiao B, Santos JS, Syeda R, Grandl J, Spencer KS, Kim SE, Schmidt M, Mathur J, Dubin AE, Montal M, Patapoutian A. Piezo proteins are pore-forming subunits of mechanically activated channels. Nature. 483: 176-81. PMID 22343900 DOI: 10.1038/nature10812  0.92
2012 Kim SE, Coste B, Chadha A, Cook B, Patapoutian A. The role of Drosophila Piezo in mechanical nociception. Nature. 483: 209-12. PMID 22343891 DOI: 10.1038/nature10801  0.92
2011 Blasius AL, Dubin AE, Petrus MJ, Lim BK, Narezkina A, Criado JR, Wills DN, Xia Y, Moresco EM, Ehlers C, Knowlton KU, Patapoutian A, Beutler B. Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype. Proceedings of the National Academy of Sciences of the United States of America. 108: 19413-8. PMID 22087007 DOI: 10.1073/pnas.1117020108  0.92
2011 Miyamoto T, Patapoutian A. Why does morphine make you itch? Cell. 147: 261-2. PMID 22000005 DOI: 10.1016/j.cell.2011.09.026  0.92
2011 Miyamoto T, Petrus MJ, Dubin AE, Patapoutian A. TRPV3 regulates nitric oxide synthase-independent nitric oxide synthesis in the skin. Nature Communications. 2: 369. PMID 21712817 DOI: 10.1038/ncomms1371  0.92
2011 Xiao B, Patapoutian A. Scratching the surface: a role of pain-sensing TRPA1 in itch. Nature Neuroscience. 14: 540-2. PMID 21522144 DOI: 10.1038/nn.2813  0.92
2011 Xiao B, Coste B, Mathur J, Patapoutian A. Temperature-dependent STIM1 activation induces Ca²+ influx and modulates gene expression. Nature Chemical Biology. 7: 351-8. PMID 21499266 DOI: 10.1038/nchembio.558  0.92
2010 del Camino D, Murphy S, Heiry M, Barrett LB, Earley TJ, Cook CA, Petrus MJ, Zhao M, D'Amours M, Deering N, Brenner GJ, Costigan M, Hayward NJ, Chong JA, Fanger CM, ... ... Patapoutian A, et al. TRPA1 contributes to cold hypersensitivity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15165-74. PMID 21068322 DOI: 10.1523/JNEUROSCI.2580-10.2010  0.92
2010 Dubin AE, Patapoutian A. Nociceptors: the sensors of the pain pathway. The Journal of Clinical Investigation. 120: 3760-72. PMID 21041958 DOI: 10.1172/JCI42843  0.92
2010 Coste B, Mathur J, Schmidt M, Earley TJ, Ranade S, Petrus MJ, Dubin AE, Patapoutian A. Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels. Science (New York, N.Y.). 330: 55-60. PMID 20813920 DOI: 10.1126/science.1193270  0.92
2010 Grandl J, Kim SE, Uzzell V, Bursulaya B, Petrus M, Bandell M, Patapoutian A. Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain. Nature Neuroscience. 13: 708-14. PMID 20414199 DOI: 10.1038/nn.2552  0.92
2010 Macpherson LJ, Patapoutian A. Channels: flies feel your pain. Nature Chemical Biology. 6: 252-3. PMID 20300095 DOI: 10.1038/nchembio.339  0.92
2009 Bandell M, Patapoutian A. Itching for insight. Cell. 139: 1224-6. PMID 20064368 DOI: 10.1016/j.cell.2009.12.012  0.92
2009 Schmidt M, Dubin AE, Petrus MJ, Earley TJ, Patapoutian A. Nociceptive signals induce trafficking of TRPA1 to the plasma membrane. Neuron. 64: 498-509. PMID 19945392 DOI: 10.1016/j.neuron.2009.09.030  0.92
2009 Miyamoto T, Dubin AE, Petrus MJ, Patapoutian A. TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice. Plos One. 4: e7596. PMID 19893614 DOI: 10.1371/journal.pone.0007596  0.92
2009 Mandadi S, Sokabe T, Shibasaki K, Katanosaka K, Mizuno A, Moqrich A, Patapoutian A, Fukumi-Tominaga T, Mizumura K, Tominaga M. TRPV3 in keratinocytes transmits temperature information to sensory neurons via ATP. PflüGers Archiv : European Journal of Physiology. 458: 1093-102. PMID 19669158 DOI: 10.1007/s00424-009-0703-x  0.92
2009 Mandadi S, Nakanishi ST, Takashima Y, Dhaka A, Patapoutian A, McKemy DD, Whelan PJ. Locomotor networks are targets of modulation by sensory transient receptor potential vanilloid 1 and transient receptor potential melastatin 8 channels. Neuroscience. 162: 1377-97. PMID 19482068 DOI: 10.1016/j.neuroscience.2009.05.063  0.92
2009 Hu H, Bandell M, Petrus MJ, Zhu MX, Patapoutian A. Zinc activates damage-sensing TRPA1 ion channels. Nature Chemical Biology. 5: 183-90. PMID 19202543 DOI: 10.1038/nchembio.146  0.92
2009 Hu H, Grandl J, Bandell M, Petrus M, Patapoutian A. Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4. Proceedings of the National Academy of Sciences of the United States of America. 106: 1626-31. PMID 19164517 DOI: 10.1073/pnas.0812209106  0.92
2009 Dhaka A, Uzzell V, Dubin AE, Mathur J, Petrus M, Bandell M, Patapoutian A. TRPV1 is activated by both acidic and basic pH. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 153-8. PMID 19129393 DOI: 10.1523/JNEUROSCI.4901-08.2009  0.92
2009 Patapoutian A, Tate S, Woolf CJ. Transient receptor potential channels: targeting pain at the source. Nature Reviews. Drug Discovery. 8: 55-68. PMID 19116627 DOI: 10.1038/nrd2757  0.92
2008 Grandl J, Hu H, Bandell M, Bursulaya B, Schmidt M, Petrus M, Patapoutian A. Pore region of TRPV3 ion channel is specifically required for heat activation. Nature Neuroscience. 11: 1007-13. PMID 19160498 DOI: 10.1038/nn.2169  0.92
2008 Xiao B, Dubin AE, Bursulaya B, Viswanath V, Jegla TJ, Patapoutian A. Identification of transmembrane domain 5 as a critical molecular determinant of menthol sensitivity in mammalian TRPA1 channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 9640-51. PMID 18815250 DOI: 10.1523/JNEUROSCI.2772-08.2008  0.92
2008 Dhaka A, Earley TJ, Watson J, Patapoutian A. Visualizing cold spots: TRPM8-expressing sensory neurons and their projections. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 566-75. PMID 18199758 DOI: 10.1523/JNEUROSCI.3976-07.2008  0.92
2007 Petrus M, Peier AM, Bandell M, Hwang SW, Huynh T, Olney N, Jegla T, Patapoutian A. A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition. Molecular Pain. 3: 40. PMID 18086313 DOI: 10.1186/1744-8069-3-40  0.92
2007 Macpherson LJ, Xiao B, Kwan KY, Petrus MJ, Dubin AE, Hwang S, Cravatt B, Corey DP, Patapoutian A. An ion channel essential for sensing chemical damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11412-5. PMID 17942735 DOI: 10.1523/JNEUROSCI.3600-07.2007  0.92
2007 Bandell M, Macpherson LJ, Patapoutian A. From chills to chilis: mechanisms for thermosensation and chemesthesis via thermoTRPs. Current Opinion in Neurobiology. 17: 490-7. PMID 17706410 DOI: 10.1016/j.conb.2007.07.014  0.92
2007 Dhaka A, Murray AN, Mathur J, Earley TJ, Petrus MJ, Patapoutian A. TRPM8 is required for cold sensation in mice. Neuron. 54: 371-8. PMID 17481391 DOI: 10.1016/j.neuron.2007.02.024  0.92
2007 Kindt KS, Viswanath V, Macpherson L, Quast K, Hu H, Patapoutian A, Schafer WR. Caenorhabditis elegans TRPA-1 functions in mechanosensation. Nature Neuroscience. 10: 568-77. PMID 17450139 DOI: 10.1038/nn1886  0.92
2007 Macpherson LJ, Dubin AE, Evans MJ, Marr F, Schultz PG, Cravatt BF, Patapoutian A. Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines. Nature. 445: 541-5. PMID 17237762 DOI: 10.1038/nature05544  0.92
2006 McCleverty CJ, Koesema E, Patapoutian A, Lesley SA, Kreusch A. Crystal structure of the human TRPV2 channel ankyrin repeat domain. Protein Science : a Publication of the Protein Society. 15: 2201-6. PMID 16882997 DOI: 10.1110/ps.062357206  0.92
2006 Saghatelian A, McKinney MK, Bandell M, Patapoutian A, Cravatt BF. A FAAH-regulated class of N-acyl taurines that activates TRP ion channels. Biochemistry. 45: 9007-15. PMID 16866345 DOI: 10.1021/bi0608008  0.92
2006 Macpherson LJ, Hwang SW, Miyamoto T, Dubin AE, Patapoutian A, Story GM. More than cool: promiscuous relationships of menthol and other sensory compounds. Molecular and Cellular Neurosciences. 32: 335-43. PMID 16829128 DOI: 10.1016/j.mcn.2006.05.005  0.92
2006 Dhaka A, Viswanath V, Patapoutian A. Trp ion channels and temperature sensation. Annual Review of Neuroscience. 29: 135-61. PMID 16776582 DOI: 10.1146/annurev.neuro.29.051605.112958  0.92
2006 Patapoutian A, Macpherson L. Channeling pain. Nature Medicine. 12: 506-7. PMID 16675993 DOI: 10.1038/nm0506-506  0.92
2006 Bandell M, Dubin AE, Petrus MJ, Orth A, Mathur J, Hwang SW, Patapoutian A. High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol. Nature Neuroscience. 9: 493-500. PMID 16520735 DOI: 10.1038/nn1665  0.92
2005 Macpherson LJ, Geierstanger BH, Viswanath V, Bandell M, Eid SR, Hwang S, Patapoutian A. The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin. Current Biology : Cb. 15: 929-34. PMID 15916949 DOI: 10.1016/j.cub.2005.04.018  0.92
2005 Moqrich A, Hwang SW, Earley TJ, Petrus MJ, Murray AN, Spencer KS, Andahazy M, Story GM, Patapoutian A. Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin. Science (New York, N.Y.). 307: 1468-72. PMID 15746429 DOI: 10.1126/science.1108609  0.92
2005 Patapoutian A. TRP channels and thermosensation. Chemical Senses. 30: i193-4. PMID 15738110 DOI: 10.1093/chemse/bjh180  0.92
2005 Rosenzweig M, Brennan KM, Tayler TD, Phelps PO, Patapoutian A, Garrity PA. The Drosophila ortholog of vertebrate TRPA1 regulates thermotaxis. Genes & Development. 19: 419-24. PMID 15681611 DOI: 10.1101/gad.1278205  0.92
2004 Moqrich A, Earley TJ, Watson J, Andahazy M, Backus C, Martin-Zanca D, Wright DE, Reichardt LF, Patapoutian A. Expressing TrkC from the TrkA locus causes a subset of dorsal root ganglia neurons to switch fate. Nature Neuroscience. 7: 812-8. PMID 15247919 DOI: 10.1038/nn1283  0.92
2004 Bandell M, Story GM, Hwang SW, Viswanath V, Eid SR, Petrus MJ, Earley TJ, Patapoutian A. Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron. 41: 849-57. PMID 15046718 DOI: 10.1016/S0896-6273(04)00150-3  0.92
2004 Patapoutian A, Wood JN. Introduction to the Journal of Neurobiology special issue on nociception Journal of Neurobiology. 61: 1-2. DOI: 10.1002/neu.20092  0.92
2003 Patapoutian A, Peier AM, Story GM, Viswanath V. ThermoTRP channels and beyond: mechanisms of temperature sensation. Nature Reviews. Neuroscience. 4: 529-39. PMID 12838328 DOI: 10.1038/nrn1141  0.92
2003 Viswanath V, Story GM, Peier AM, Petrus MJ, Lee VM, Hwang SW, Patapoutian A, Jegla T. Opposite thermosensor in fruitfly and mouse. Nature. 423: 822-3. PMID 12815418 DOI: 10.1038/423822a  0.92
2003 Story GM, Peier AM, Reeve AJ, Eid SR, Mosbacher J, Hricik TR, Earley TJ, Hergarden AC, Andersson DA, Hwang SW, McIntyre P, Jegla T, Bevan S, Patapoutian A. ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell. 112: 819-29. PMID 12654248 DOI: 10.1016/S0092-8674(03)00158-2  0.92
2002 Peier AM, Reeve AJ, Andersson DA, Moqrich A, Earley TJ, Hergarden AC, Story GM, Colley S, Hogenesch JB, McIntyre P, Bevan S, Patapoutian A. A heat-sensitive TRP channel expressed in keratinocytes. Science (New York, N.Y.). 296: 2046-9. PMID 12016205 DOI: 10.1126/science.1073140  0.92
2002 Su AI, Cooke MP, Ching KA, Hakak Y, Walker JR, Wiltshire T, Orth AP, Vega RG, Sapinoso LM, Moqrich A, Patapoutian A, Hampton GM, Schultz PG, Hogenesch JB. Large-scale analysis of the human and mouse transcriptomes. Proceedings of the National Academy of Sciences of the United States of America. 99: 4465-70. PMID 11904358 DOI: 10.1073/pnas.012025199  0.92
2002 Peier AM, Moqrich A, Hergarden AC, Reeve AJ, Andersson DA, Story GM, Earley TJ, Dragoni I, McIntyre P, Bevan S, Patapoutian A. A TRP channel that senses cold stimuli and menthol. Cell. 108: 705-15. PMID 11893340 DOI: 10.1016/S0092-8674(02)00652-9  0.92
2001 Patapoutian A. Making the pain connection. Neuron. 31: 4-6. PMID 11498043 DOI: 10.1016/S0896-6273(01)00352-X  0.92
2001 Patapoutian A, Reichardt LF. Trk receptors: mediators of neurotrophin action. Current Opinion in Neurobiology. 11: 272-80. PMID 11399424 DOI: 10.1016/S0959-4388(00)00208-7  0.92
2000 Patapoutian A, Reichardt LF. Roles of Wnt proteins in neural development and maintenance. Current Opinion in Neurobiology. 10: 392-9. PMID 10851180 DOI: 10.1016/S0959-4388(00)00100-8  0.92
1999 Patapoutian A, Backus C, Kispert A, Reichardt LF. Regulation of neurotrophin-3 expression by epithelial-mesenchymal interactions: the role of Wnt factors. Science (New York, N.Y.). 283: 1180-3. PMID 10024246 DOI: 10.1126/science.283.5405.1180  0.92
1998 Fariñas I, Wilkinson GA, Backus C, Reichardt LF, Patapoutian A. Characterization of neurotrophin and Trk receptor functions in developing sensory ganglia: direct NT-3 activation of TrkB neurons in vivo. Neuron. 21: 325-34. PMID 9728914  0.92
1995 Patapoutian A, Wold BJ, Wagner RA. Evidence for developmentally programmed transdifferentiation in mouse esophageal muscle. Science (New York, N.Y.). 270: 1818-21. PMID 8525375  0.92
1995 Patapoutian A, Yoon JK, Miner JH, Wang S, Stark K, Wold B. Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome. Development (Cambridge, England). 121: 3347-58. PMID 7588068  0.92
1993 Patapoutian A, Miner JH, Lyons GE, Wold B. Isolated sequences from the linked Myf-5 and MRF4 genes drive distinct patterns of muscle-specific expression in transgenic mice. Development (Cambridge, England). 118: 61-9. PMID 8375340  0.92
1991 Verma R, Patapoutian A, Gordon CB, Campbell JL. Identification and purification of a factor that binds to the Mlu I cell cycle box of yeast DNA replication genes. Proceedings of the National Academy of Sciences of the United States of America. 88: 7155-9. PMID 1871128  0.92
1990 Pignoni F, Baldarelli RM, Steingrímsson E, Diaz RJ, Patapoutian A, Merriam JR, Lengyel JA. The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid receptor superfamily. Cell. 62: 151-63. PMID 2364433 DOI: 10.1016/0092-8674(90)90249-E  0.92
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