Andrew A. Pieper - Publications

2001 Johns Hopkins University, Baltimore, MD 

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Vázquez-Rosa E, Shin MK, Dhar M, Chaubey K, Cintrón-Pérez CJ, Tang X, Liao X, Miller E, Koh Y, Barker S, Franke K, Crosby DR, Schroeder R, Emery J, Yin TC, ... ... Pieper AA, et al. P7C3-A20 treatment one year after TBI in mice repairs the blood-brain barrier, arrests chronic neurodegeneration, and restores cognition. Proceedings of the National Academy of Sciences of the United States of America. PMID 33087571 DOI: 10.1073/pnas.2010430117  1
2020 Sridharan PS, Lu Y, Rice RC, Pieper AA, Rajadhyaksha AM. Loss of Cav1.2 channels impairs hippocampal theta burst stimulation-induced long-term potentiation. Channels (Austin, Tex.). 14: 287-293. PMID 32799605 DOI: 10.1080/19336950.2020.1807851  1
2020 Bavley CC, Kabir ZD, Walsh AP, Kosovsky M, Hackett J, Sun H, Vázquez-Rosa E, Cintrón-Pérez CJ, Miller E, Koh Y, Pieper AA, Rajadhyaksha AM. Dopamine D1R-neuron cacna1c deficiency: a new model of extinction therapy-resistant post-traumatic stress. Molecular Psychiatry. PMID 32332995 DOI: 10.1038/s41380-020-0730-8  1
2020 Harper MM, Rudd D, Meyer KJ, Kanthasamy AG, Anantharam V, Pieper AA, Vázquez-Rosa E, Shin MK, Chaubey K, Koh Y, Evans LP, Bassuk AG, Anderson MG, Dutca L, Kudva IT, et al. Identification of chronic brain protein changes and protein targets of serum auto-antibodies after blast-mediated traumatic brain injury. Heliyon. 6: e03374. PMID 32099918 DOI: 10.1016/j.heliyon.2020.e03374  1
2019 Pieper AA, McKnight SL. Benefits of Enhancing Nicotinamide Adenine Dinucleotide Levels in Damaged or Diseased Nerve Cells. Cold Spring Harbor Symposia On Quantitative Biology. PMID 30787047 DOI: 10.1101/sqb.2018.83.037622  1
2019 Voorhees JR, Remy MT, Erickson CM, Dutca LM, Brat DJ, Pieper AA. Occupational-like organophosphate exposure disrupts microglia and accelerates deficits in a rat model of Alzheimer's disease. Npj Aging and Mechanisms of Disease. 5: 3. PMID 30701080 DOI: 10.1038/s41514-018-0033-3  1
2018 Vázquez-Rosa E, Watson MR, Sahn JJ, Hodges TR, Schroeder RE, Cintrón-Pérez CJ, Shin MK, Yin TC, Emery JL, Martin SF, Liebl DJ, Pieper A. Neuroprotective Efficacy of a Novel Sigma 2 Receptor/TMEM97 Modulator (DKR-1677) after Traumatic Brain Injury. Acs Chemical Neuroscience. PMID 30421909 DOI: 10.1021/acschemneuro.8b00543  1
2018 Genova RM, Meyer KJ, Anderson MG, Harper MM, Pieper AA. Neprilysin inhibition promotes corneal wound healing. Scientific Reports. 8: 14385. PMID 30258206 DOI: 10.1038/s41598-018-32773-9  1
2018 Bauman MD, Schumann CM, Carlson EL, Taylor SL, Vázquez-Rosa E, Cintrón-Pérez CJ, Shin MK, Williams NS, Pieper AA. Neuroprotective efficacy of P7C3 compounds in primate hippocampus. Translational Psychiatry. 8: 202. PMID 30258178 DOI: 10.1038/s41398-018-0244-1  1
2018 Blaya MO, Wasserman JM, Pieper AA, Sick TJ, Bramlett HM, Dietrich WD. Neurotherapeutic Capacity of P7C3 Agents for the Treatment of Traumatic Brain Injury. Neuropharmacology. PMID 30236963 DOI: 10.1016/j.neuropharm.2018.09.024  1
2018 Yang T, Britt JK, Cintrón-Pérez CJ, Vázquez-Rosa E, Tobin KV, Stalker G, Hardie J, Taugher RJ, Wemmie J, Pieper AA, Lee A. Ca binding protein 1 regulates hippocampal-dependent memory and synaptic plasticity. Neuroscience. PMID 29660444 DOI: 10.1016/j.neuroscience.2018.04.004  1
2018 Na ES, De Jesús-Cortés H, Martinez-Rivera A, Kabir ZD, Wang J, Ramesh V, Onder Y, Rajadhyaksha AM, Monteggia LM, Pieper AA. Correction: D-cycloserine improves synaptic transmission in an animal mode of Rett syndrome. Plos One. 13: e0192057. PMID 29370281 DOI: 10.1371/journal.pone.0192057  1
2017 Voorhees JR, Remy MT, Cintrón-Pérez CJ, El Rassi E, Khan MZ, Dutca LM, Yin TC, McDaniel LN, Williams NS, Brat DJ, Pieper AA. (-)-P7C3-S243 Protects a Rat Model of Alzheimer's Disease From Neuropsychiatric Deficits and Neurodegeneration Without Altering Amyloid Deposition or Reactive Glia. Biological Psychiatry. PMID 29246437 DOI: 10.1016/j.biopsych.2017.10.023  1
2017 Broussard JI, Acion L, De Jesús-Cortés H, Yin T, Britt JK, Salas R, Costa-Mattioli M, Robertson C, Pieper AA, Arciniegas DB, Jorge R. Repeated mild traumatic brain injury produces neuroinflammation, anxiety-like behaviour and impaired spatial memory in mice. Brain Injury. 1-10. PMID 29156991 DOI: 10.1080/02699052.2017.1380228  1
2017 Loris ZB, Hynton JR, Pieper AA, Dietrich WD. Beneficial Effects of Delayed P7C3-A20 Treatment After Transient MCAO in Rats. Translational Stroke Research. PMID 28842830 DOI: 10.1007/s12975-017-0565-z  1
2017 Na ES, De Jesús-Cortés H, Martinez-Rivera A, Kabir ZD, Wang J, Ramesh V, Onder Y, Rajadhyaksha AM, Monteggia LM, Pieper AA. D-cycloserine improves synaptic transmission in an animal mode of Rett syndrome. Plos One. 12: e0183026. PMID 28813484 DOI: 10.1371/journal.pone.0183026  1
2017 Loris ZB, Pieper AA, Dietrich WD. Corrigendum to "The neuroprotective compound P7C3-A20 promotes neurogenesis and improves cognitive function after stroke" [Exp. Neurol. 290 (2017) 63-73]. Experimental Neurology. PMID 28511786 DOI: 10.1016/j.expneurol.2017.04.016  1
2017 Michaelson JJ, Shin MK, Koh JY, Brueggeman L, Zhang A, Katzman A, McDaniel L, Fang M, Pufall M, Pieper AA. Neuronal PAS Domain Proteins 1 and 3 Are Master Regulators of Neuropsychiatric Risk Genes. Biological Psychiatry. PMID 28499489 DOI: 10.1016/j.biopsych.2017.03.021  1
2016 De Jesús-Cortés H, Rajadhyaksha AM, Pieper AA. Cacna1c: Protecting young hippocampal neurons in the adult brain. Neurogenesis (Austin, Tex.). 3: e1231160. PMID 27900342 DOI: 10.1080/23262133.2016.1231160  1
2016 Lutter M, Khan MZ, Satio K, Davis KC, Kidder IJ, McDaniel L, Darbro BW, Pieper AA, Cui H. The Eating-Disorder Associated HDAC4(A778T) Mutation Alters Feeding Behaviors in Female Mice. Biological Psychiatry. PMID 27884425 DOI: 10.1016/j.biopsych.2016.09.024  1
2016 Yin TC, Voorhees JR, Genova RM, Davis KC, Madison AM, Britt JK, Cintrón-Pérez CJ, McDaniel L, Harper MM, Pieper AA. Acute Axonal Degeneration Drives Development of Cognitive, Motor, and Visual Deficits after Blast-Mediated Traumatic Brain Injury in Mice. Eneuro. 3. PMID 27822499 DOI: 10.1523/ENEURO.0220-16.2016  1
2016 De Jesús-Cortés H, Lu Y, Anderson RM, Khan MZ, Nath V, McDaniel L, Lutter M, Radley JJ, Pieper AA, Cui H. Loss of estrogen-related receptor alpha disrupts ventral-striatal synaptic function in female mice. Neuroscience. PMID 27155145 DOI: 10.1016/j.neuroscience.2016.04.054  1
2016 Lee AS, De Jesús-Cortés H, Kabir ZD, Knobbe W, Orr M, Burgdorf C, Huntington P, McDaniel L, Britt JK, Hoffmann F, Brat DJ, Rajadhyaksha AM, Pieper AA. The Neuropsychiatric Disease-Associated Gene cacna1c Mediates Survival of Young Hippocampal Neurons. Eneuro. 3. PMID 27066530 DOI: 10.1523/ENEURO.0006-16.2016  1
2015 De Jesús-Cortés H, Miller AD, Britt JK, DeMarco AJ, De Jesús-Cortés M, Stuebing E, Naidoo J, Vázquez-Rosa E, Morlock L, Williams NS, Ready JM, Narayanan NS, Pieper AA. Protective efficacy of P7C3-S243 in the 6-hydroxydopamine model of Parkinson's disease. Npj Parkinson's Disease. 1. PMID 27158662 DOI: 10.1038/npjparkd.2015.10  1
2015 von Holstein-Rathlou S, BonDurant LD, Peltekian L, Naber MC, Yin TC, Claflin KE, Urizar AI, Madsen AN, Ratner C, Holst B, Karstoft K, Vandenbeuch A, Anderson CB, Cassell MD, Thompson AP, ... ... Pieper AA, et al. FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver. Cell Metabolism. PMID 26724858 DOI: 10.1016/j.cmet.2015.12.003  1
2015 Wang J, Wegener JE, Huang TW, Sripathy S, De Jesus-Cortes H, Xu P, Tran S, Knobbe W, Leko V, Britt J, Starwalt R, McDaniel L, Ward CS, Parra D, Newcomb B, ... ... Pieper AA, et al. Corrigendum: Wild-type microglia do not reverse pathology in mouse models of Rett syndrome. Nature. PMID 26176914 DOI: 10.1038/nature14671  1
2015 Wang J, Wegener JE, Huang TW, Sripathy S, De Jesus-Cortes H, Xu P, Tran S, Knobbe W, Leko V, Britt J, Starwalt R, McDaniel L, Ward CS, Parra D, Newcomb B, ... ... Pieper AA, et al. Wild-type microglia do not reverse pathology in mouse models of Rett syndrome. Nature. 521: E1-4. PMID 25993969 DOI: 10.1038/nature14444  1
2015 Cui H, Lu Y, Khan MZ, Anderson RM, McDaniel L, Wilson HE, Yin TC, Radley JJ, Pieper AA, Lutter M. Behavioral disturbances in estrogen-related receptor alpha-null mice. Cell Reports. 11: 344-50. PMID 25865889 DOI: 10.1016/j.celrep.2015.03.032  1
2015 Kemp SW, Szynkaruk M, Stanoulis KN, Wood MD, Liu EH, Willand MP, Morlock L, Naidoo J, Williams NS, Ready JM, Mangano TJ, Beggs S, Salter MW, Gordon T, Pieper AA, et al. Pharmacologic rescue of motor and sensory function by the neuroprotective compound P7C3 following neonatal nerve injury. Neuroscience. 284: 202-16. PMID 25313000 DOI: 10.1016/j.neuroscience.2014.10.005  1
2015 Walker AK, Rivera PD, Wang Q, Chuang JC, Tran S, Osborne-Lawrence S, Estill SJ, Starwalt R, Huntington P, Morlock L, Naidoo J, Williams NS, Ready JM, Eisch AJ, Pieper AA, et al. The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis. Molecular Psychiatry. 20: 500-8. PMID 24751964 DOI: 10.1038/mp.2014.34  1
2014 Dutca LM, Stasheff SF, Hedberg-Buenz A, Rudd DS, Batra N, Blodi FR, Yorek MS, Yin T, Shankar M, Herlein JA, Naidoo J, Morlock L, Williams N, Kardon RH, Anderson MG, ... Pieper AA, et al. Early detection of subclinical visual damage after blast-mediated TBI enables prevention of chronic visual deficit by treatment with P7C3-S243. Investigative Ophthalmology & Visual Science. 55: 8330-41. PMID 25468886 DOI: 10.1167/iovs.14-15468  1
2014 Stanco A, Pla R, Vogt D, Chen Y, Mandal S, Walker J, Hunt RF, Lindtner S, Erdman CA, Pieper AA, Hamilton SP, Xu D, Baraban SC, Rubenstein JL. NPAS1 represses the generation of specific subtypes of cortical interneurons. Neuron. 84: 940-53. PMID 25467980 DOI: 10.1016/j.neuron.2014.10.040  1
2014 Yin TC, Britt JK, De Jesús-Cortés H, Lu Y, Genova RM, Khan MZ, Voorhees JR, Shao J, Katzman AC, Huntington PJ, Wassink C, McDaniel L, Newell EA, Dutca LM, Naidoo J, ... ... Pieper AA, et al. P7C3 neuroprotective chemicals block axonal degeneration and preserve function after traumatic brain injury. Cell Reports. 8: 1731-40. PMID 25220467 DOI: 10.1016/j.celrep.2014.08.030  1
2014 Wang G, Han T, Nijhawan D, Theodoropoulos P, Naidoo J, Yadavalli S, Mirzaei H, Pieper AA, Ready JM, McKnight SL. P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage. Cell. 158: 1324-34. PMID 25215490 DOI: 10.1016/j.cell.2014.07.040  1
2014 Naidoo J, De Jesus-Cortes H, Huntington P, Estill S, Morlock LK, Starwalt R, Mangano TJ, Williams NS, Pieper AA, Ready JM. Discovery of a neuroprotective chemical, (S)-N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine [(-)-P7C3-S243], with improved druglike properties. Journal of Medicinal Chemistry. 57: 3746-54. PMID 24697290 DOI: 10.1021/jm401919s  1
2014 Pieper AA, McKnight SL, Ready JM. P7C3 and an unbiased approach to drug discovery for neurodegenerative diseases. Chemical Society Reviews. 43: 6716-26. PMID 24514864 DOI: 10.1039/c3cs60448a  1
2014 Blaya MO, Bramlett HM, Naidoo J, Pieper AA, Dietrich WD. Neuroprotective efficacy of a proneurogenic compound after traumatic brain injury. Journal of Neurotrauma. 31: 476-86. PMID 24070637 DOI: 10.1089/neu.2013.3135  1
2013 Paemka L, Mahajan VB, Skeie JM, Sowers LP, Ehaideb SN, Gonzalez-Alegre P, Sasaoka T, Tao H, Miyagi A, Ueno N, Takao K, Miyakawa T, Wu S, Darbro BW, Ferguson PJ, ... Pieper AA, et al. PRICKLE1 interaction with SYNAPSIN I reveals a role in autism spectrum disorders. Plos One. 8: e80737. PMID 24312498 DOI: 10.1371/journal.pone.0080737  1
2013 Cui H, Moore J, Ashimi SS, Mason BL, Drawbridge JN, Han S, Hing B, Matthews A, McAdams CJ, Darbro BW, Pieper AA, Waller DA, Xing C, Lutter M. Eating disorder predisposition is associated with ESRRA and HDAC4 mutations. The Journal of Clinical Investigation. 123: 4706-13. PMID 24216484 DOI: 10.1172/JCI71400  1
2013 Buchovecky CM, Turley SD, Brown HM, Kyle SM, McDonald JG, Liu B, Pieper AA, Huang W, Katz DM, Russell DW, Shendure J, Justice MJ. A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett syndrome. Nature Genetics. 45: 1013-20. PMID 23892605 DOI: 10.1038/ng.2714  1
2013 Xu P, Grueter BA, Britt JK, McDaniel L, Huntington PJ, Hodge R, Tran S, Mason BL, Lee C, Vong L, Lowell BB, Malenka RC, Lutter M, Pieper AA. Double deletion of melanocortin 4 receptors and SAPAP3 corrects compulsive behavior and obesity in mice. Proceedings of the National Academy of Sciences of the United States of America. 110: 10759-64. PMID 23754400 DOI: 10.1073/pnas.1308195110  1
2013 Naidoo J, Bemben CJ, Allwein SR, Liang J, Pieper AA, Ready JM. Development of a scalable synthesis of P7C3-A20, a potent neuroprotective agent Tetrahedron Letters. 54: 4429-4431. DOI: 10.1016/j.tetlet.2013.06.024  1
2012 Lee AS, Gonzales KL, Lee A, Moosmang S, Hofmann F, Pieper AA, Rajadhyaksha AM. Selective genetic deletion of cacna1c in the mouse prefrontal cortex. Molecular Psychiatry. 17: 1051. PMID 23096954 DOI: 10.1038/mp.2012.149  1
2012 De Jesús-Cortés H, Xu P, Drawbridge J, Estill SJ, Huntington P, Tran S, Britt J, Tesla R, Morlock L, Naidoo J, Melito LM, Wang G, Williams NS, Ready JM, McKnight SL, ... Pieper AA, et al. Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease. Proceedings of the National Academy of Sciences of the United States of America. 109: 17010-5. PMID 23027934 DOI: 10.1073/pnas.1213956109  1
2012 Tesla R, Wolf HP, Xu P, Drawbridge J, Estill SJ, Huntington P, McDaniel L, Knobbe W, Burket A, Tran S, Starwalt R, Morlock L, Naidoo J, Williams NS, Ready JM, ... ... Pieper AA, et al. Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 109: 17016-21. PMID 23027932 DOI: 10.1073/pnas.1213960109  1
2012 Lee AS, Ra S, Rajadhyaksha AM, Britt JK, De Jesus-Cortes H, Gonzales KL, Lee A, Moosmang S, Hofmann F, Pieper AA, Rajadhyaksha AM. Forebrain elimination of cacna1c mediates anxiety-like behavior in mice. Molecular Psychiatry. 17: 1054-5. PMID 22665262 DOI: 10.1038/mp.2012.71  1
2011 Watkins CC, Pieper AA, Treisman GJ. Safety considerations in drug treatment of depression in HIV-positive patients: an updated review. Drug Safety. 34: 623-39. PMID 21751824 DOI: 10.2165/11592070-000000000-00000  1
2011 Aqul A, Liu B, Ramirez CM, Pieper AA, Estill SJ, Burns DK, Liu B, Repa JJ, Turley SD, Dietschy JM. Unesterified cholesterol accumulation in late endosomes/lysosomes causes neurodegeneration and is prevented by driving cholesterol export from this compartment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 9404-13. PMID 21697390 DOI: 10.1523/JNEUROSCI.1317-11.2011  1
2011 MacMillan KS, Naidoo J, Liang J, Melito L, Williams NS, Morlock L, Huntington PJ, Estill SJ, Longgood J, Becker GL, McKnight SL, Pieper AA, De Brabander JK, Ready JM. Development of proneurogenic, neuroprotective small molecules. Journal of the American Chemical Society. 133: 1428-37. PMID 21210688 DOI: 10.1021/ja108211m  1
2010 Pieper AA, Xie S, Capota E, Estill SJ, Zhong J, Long JM, Becker GL, Huntington P, Goldman SE, Shen CH, Capota M, Britt JK, Kotti T, Ure K, Brat DJ, et al. Discovery of a proneurogenic, neuroprotective chemical. Cell. 142: 39-51. PMID 20603013 DOI: 10.1016/j.cell.2010.06.018  1
2008 Zhao H, Negash L, Wei Q, LaCour TG, Estill SJ, Capota E, Pieper AA, Harran PG. Acid promoted cinnamyl ion mobility within peptide derived macrocycles Journal of the American Chemical Society. 130: 13864-13866. PMID 18811162 DOI: 10.1021/ja803299h  1
2005 Pieper AA, Wu X, Han TW, Estill SJ, Dang Q, Wu LC, Reece-Fincanon S, Dudley CA, Richardson JA, Brat DJ, McKnight SL. The neuronal PAS domain protein 3 transcription factor controls FGF-mediated adult hippocampal neurogenesis in mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 14052-7. PMID 16172381 DOI: 10.1073/pnas.0506713102  1
2005 Pieper AA, Treisman GJ. Drug treatment of depression in HIV-positive patients : safety considerations. Drug Safety. 28: 753-62. PMID 16119970 DOI: 10.2165/00002018-200528090-00002  1
2001 Pieper AA, Brat DJ, O'Hearn E, Krug DK, Kaplin AI, Takahashi K, Greenberg JH, Ginty D, Molliver ME, Snyder SH. Differential neuronal localizations and dynamics of phosphorylated and unphosphorylated type 1 inositol 1,4,5-trisphosphate receptors. Neuroscience. 102: 433-44. PMID 11166129 DOI: 10.1016/S0306-4522(00)00470-X  1
2000 Pieper AA, Walles T, Wei G, Clements EE, Verma A, Snyder SH, Zweier JL. Myocardial postischemic injury is reduced by polyADPripose polymerase-1 gene disruption. Molecular Medicine (Cambridge, Mass.). 6: 271-82. PMID 10949908  1
2000 Pieper AA, Blackshaw S, Clements EE, Brat DJ, Krug DK, White AJ, Pinto-Garcia P, Favit A, Conover JR, Snyder SH, Verma A. Poly(ADP-ribosyl)ation basally activated by DNA strand breaks reflects glutamate-nitric oxide neurotransmission. Proceedings of the National Academy of Sciences of the United States of America. 97: 1845-50. PMID 10677544 DOI: 10.1073/pnas.97.4.1845  1
1999 LaPlaca MC, Raghupathi R, Verma A, Pieper AA, Saatman KE, Snyder SH, McIntosh TK. Temporal patterns of poly(ADP-ribose) polymerase activation in the cortex following experimental brain injury in the rat. Journal of Neurochemistry. 73: 205-13. PMID 10386972 DOI: 10.1046/j.1471-4159.1999.0730205.x  1
1999 Takahashi K, Pieper AA, Croul SE, Zhang J, Snyder SH, Greenberg JH. Post-treatment with an inhibitor of poly(ADP-ribose) polymerase attenuates cerebral damage in focal ischemia. Brain Research. 829: 46-54. PMID 10350529 DOI: 10.1016/S0006-8993(99)01335-9  1
1999 Pieper AA, Verma A, Zhang J, Snyder SH. Poly (ADP-ribose) polymerase, nitric oxide and cell death. Trends in Pharmacological Sciences. 20: 171-81. PMID 10322503 DOI: 10.1016/S0165-6147(99)01292-4  1
1999 Pieper AA, Brat DJ, Krug DK, Watkins CC, Gupta A, Blackshaw S, Verma A, Wang ZQ, Snyder SH. Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes. Proceedings of the National Academy of Sciences of the United States of America. 96: 3059-64. PMID 10077636 DOI: 10.1073/pnas.96.6.3059  1
1997 Eliasson MJ, Sampei K, Mandir AS, Hurn PD, Traystman RJ, Bao J, Pieper A, Wang ZQ, Dawson TM, Snyder SH, Dawson VL. Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. Nature Medicine. 3: 1089-95. PMID 9334719 DOI: 10.1038/nm1097-1089  1
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