Tim West, Ph.D. - Publications

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
Alzheimer's, amyloid

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Paterson RW, Gabelle A, Lucey BP, Barthélemy NR, Leckey CA, Hirtz C, Lehmann S, Sato C, Patterson BW, West T, Yarasheski K, Rohrer JD, Wildburger NC, Schott JM, Karch CM, et al. SILK studies - capturing the turnover of proteins linked to neurodegenerative diseases. Nature Reviews. Neurology. PMID 31222062 DOI: 10.1038/s41582-019-0222-0  0.44
2017 Yanamandra K, Patel TK, Jiang H, Schindler S, Ulrich JD, Boxer AL, Miller BL, Kerwin DR, Gallardo G, Stewart F, Finn MB, Cairns NJ, Verghese PB, Fogelman I, West T, et al. Anti-tau antibody administration increases plasma tau in transgenic mice and patients with tauopathy. Science Translational Medicine. 9. PMID 28424326 DOI: 10.1126/scitranslmed.aal2029  0.72
2017 Schoenfeld HA, West T, Verghese PB, Holubasch M, Shenoy N, Kagan D, Buono C, Zhou W, DeCristofaro M, Douville J, Goodrich GG, Mansfield K, Saravanan C, Cumin F, Webb RL, et al. The effect of angiotensin receptor neprilysin inhibitor, sacubitril/valsartan, on central nervous system amyloid-β concentrations and clearance in the cynomolgus monkey. Toxicology and Applied Pharmacology. PMID 28315356 DOI: 10.1016/j.taap.2017.03.014  0.44
2016 Ghosal K, Haag M, Verghese PB, West T, Veenstra T, Braunstein JB, Bateman RJ, Holtzman DM, Landreth GE. A randomized controlled study to evaluate the effect of bexarotene on amyloid-β and apolipoprotein E metabolism in healthy subjects. Alzheimer's & Dementia (New York, N. Y.). 2: 110-120. PMID 29067298 DOI: 10.1016/j.trci.2016.06.001  0.72
2014 Sheline YI, West T, Yarasheski K, Jasielec MS, Hettinger JC, Tripoli DL, Xiong C, Frederiksen C, Grzelak MV, Bateman RJ, Morris JC, Lee JM, Cirrito JR. Reply to comment on "An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice". Science Translational Medicine. 6: 268lr4. PMID 25540323 DOI: 10.1126/scitranslmed.3010609  0.72
2014 Sheline YI, West T, Yarasheski K, Swarm R, Jasielec MS, Fisher JR, Ficker WD, Yan P, Xiong C, Frederiksen C, Grzelak MV, Chott R, Bateman RJ, Morris JC, Mintun MA, et al. An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice. Science Translational Medicine. 6: 236re4. PMID 24828079 DOI: 10.1126/scitranslmed.3008169  0.72
2014 Snyder HM, Carrillo MC, Grodstein F, Henriksen K, Jeromin A, Lovestone S, Mielke MM, O'Bryant S, Sarasa M, Sjøgren M, Soares H, Teeling J, Trushina E, Ward M, West T, et al. Developing novel blood-based biomarkers for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 109-14. PMID 24365657 DOI: 10.1016/j.jalz.2013.10.007  0.72
2013 West TW. Transverse myelitis--a review of the presentation, diagnosis, and initial management. Discovery Medicine. 16: 167-77. PMID 24099672  0.72
2012 Xiao Q, Ford AL, Xu J, Yan P, Lee KY, Gonzales E, West T, Holtzman DM, Lee JM. Bcl-x pre-mRNA splicing regulates brain injury after neonatal hypoxia-ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 13587-96. PMID 23015448 DOI: 10.1523/JNEUROSCI.2617-12.2012  0.72
2012 West TW, Hess C, Cree BA. Acute transverse myelitis: demyelinating, inflammatory, and infectious myelopathies. Seminars in Neurology. 32: 97-113. PMID 22961185 DOI: 10.1055/s-0032-1322586  0.72
2012 Castellano JM, Deane R, Gottesdiener AJ, Verghese PB, Stewart FR, West T, Paoletti AC, Kasper TR, DeMattos RB, Zlokovic BV, Holtzman DM. Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis. Proceedings of the National Academy of Sciences of the United States of America. 109: 15502-7. PMID 22927427 DOI: 10.1073/pnas.1206446109  0.72
2012 Jiang M, Wang J, Fu J, Du L, Jeong H, West T, Xiang L, Peng Q, Hou Z, Cai H, Seredenina T, Arbez N, Zhu S, Sommers K, Qian J, et al. Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets. Nature Medicine. 18: 153-8. PMID 22179319 DOI: 10.1038/nm.2558  0.72
2012 West TW, Killestein J, Fox RJ. Natalizumab discontinuation: an increasingly tricky proposition. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 19: 663-4. PMID 22054207 DOI: 10.1111/j.1468-1331.2011.03574.x  0.72
2011 Lodygensky GA, West T, Moravec MD, Back SA, Dikranian K, Holtzman DM, Neil JJ. Diffusion characteristics associated with neuronal injury and glial activation following hypoxia-ischemia in the immature brain. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 66: 839-45. PMID 21394776 DOI: 10.1002/mrm.22869  0.72
2010 West TW, Cree BAC. Natalizumab dosage suspension: Are we helping or hurting? Annals of Neurology. 68: 395-399. PMID 20818793 DOI: 10.1002/ana.22163  0.72
2010 Satoh A, Brace CS, Ben-Josef G, West T, Wozniak DF, Holtzman DM, Herzog ED, Imai S. SIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 10220-32. PMID 20668205 DOI: 10.1523/JNEUROSCI.1385-10.2010  0.72
2010 Lodygensky GA, West T, Stump M, Holtzman DM, Inder TE, Neil JJ. In vivo MRI analysis of an inflammatory injury in the developing brain. Brain, Behavior, and Immunity. 24: 759-67. PMID 19945527 DOI: 10.1016/j.bbi.2009.11.005  0.72
2009 West T, Stump M, Lodygensky G, Neil JJ, Deshmukh M, Holtzman DM. Lack of X-linked inhibitor of apoptosis protein leads to increased apoptosis and tissue loss following neonatal brain injury. Asn Neuro. 1. PMID 19570023 DOI: 10.1042/AN20090005  0.72
2008 Wendland MF, Faustino J, West T, Manabat C, Holtzman DM, Vexler ZS. Early diffusion-weighted MRI as a predictor of caspase-3 activation after hypoxic-ischemic insult in neonatal rodents. Stroke; a Journal of Cerebral Circulation. 39: 1862-8. PMID 18420950 DOI: 10.1161/STROKEAHA.107.506352  0.72
2008 West T. Are initial demyelinating event recovery and time to second event under differential control? (Neurology (2006) 67 (809-813)) Neurology. 71: 1841. DOI: 10.1212/01.wnl.0000339383.07826.36  0.72
2007 West T, Atzeva M, Holtzman DM. Pomegranate polyphenols and resveratrol protect the neonatal brain against hypoxic-ischemic injury. Developmental Neuroscience. 29: 363-72. PMID 17762204 DOI: 10.1159/000105477  0.72
2006 Schlief ML, West T, Craig AM, Holtzman DM, Gitlin JD. Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity. Proceedings of the National Academy of Sciences of the United States of America. 103: 14919-24. PMID 17003121 DOI: 10.1073/pnas.0605390103  0.72
2006 West T, Atzeva M, Holtzman DM. Caspase-3 deficiency during development increases vulnerability to hypoxic-ischemic injury through caspase-3-independent pathways. Neurobiology of Disease. 22: 523-37. PMID 16480886 DOI: 10.1016/j.nbd.2005.12.017  0.72
2005 Young C, Roth KA, Klocke BJ, West T, Holtzman DM, Labruyere J, Qin YQ, Dikranian K, Olney JW. Role of caspase-3 in ethanol-induced developmental neurodegeneration. Neurobiology of Disease. 20: 608-14. PMID 15927478 DOI: 10.1016/j.nbd.2005.04.014  0.72
2005 Maas JW, Indacochea RA, Muglia LM, Tran TT, Vogt SK, West T, Benz A, Shute AA, Holtzman DM, Mennerick S, Olney JW, Muglia LJ. Calcium-stimulated adenylyl cyclases modulate ethanol-induced neurodegeneration in the neonatal brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2376-85. PMID 15745964 DOI: 10.1523/JNEUROSCI.4940-04.2005  0.72
2002 Lephart ED, West TW, Weber KS, Rhees RW, Setchell KD, Adlercreutz H, Lund TD. Neurobehavioral effects of dietary soy phytoestrogens. Neurotoxicology and Teratology. 24: 5-16. PMID 11836067 DOI: 10.1016/S0892-0362(01)00197-0  0.72
2001 Lund TD, West TW, Tian LY, Bu LH, Simmons DL, Setchell KD, Adlercreutz H, Lephart ED. Visual spatial memory is enhanced in female rats (but inhibited in males) by dietary soy phytoestrogens Bmc Neuroscience [Electronic Resource]. 2: 20. PMID 11801187  0.72
2001 Lund TD, West TW, Tian LY, Bu LH, Simmons DL, Setchell KDR, Adlercreutz H, Lephart ED. Visual spatial memory is enchanced in female rats (but inhibited in males) by dietary soy phytoestrogens Bmc Neuroscience. 2. DOI: 10.1186/1471-2202-2-20  0.72
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