Robert W. Stein, Ph.D. - Publications

Affiliations: 
Simon Fraser University, Burnaby, British Columbia, Canada 
Area:
Phylogenetics, speciation

2/259 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Stein RW, Brown JW, Mooers AØ. A molecular genetic time scale demonstrates Cretaceous origins and multiple diversification rate shifts within the order Galliformes (Aves). Molecular Phylogenetics and Evolution. PMID 26140861 DOI: 10.1016/J.Ympev.2015.06.005  0.413
2007 Kolm N, Stein RW, Mooers AØ, Verspoor JJ, Cunningham EJ. Can sexual selection drive female life histories? A comparative study on Galliform birds. Journal of Evolutionary Biology. 20: 627-38. PMID 17305829 DOI: 10.1111/j.1420-9101.2006.01248.x  0.406
Low-probability matches (unlikely to be authored by this person)
2014 Chubaty AM, Ma BO, Stein RW, Gillespie DR, Henry LM, Phelan C, Palsson E, Simon FW, Roitberg BD. On the evolution of omnivory in a community context. Ecology and Evolution. 4: 251-65. PMID 24558581 DOI: 10.1002/Ece3.923  0.245
2019 Spaeth JM, Liu JH, Peters D, Guo M, Osipovich AB, Mohammadi F, Roy N, Bhushan A, Magnuson MA, Hebrok M, Wright CVE, Stein R. The Pdx1 Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β Cell Function. Diabetes. PMID 31201281 DOI: 10.2337/Db19-0349  0.224
2003 Samaras SE, Zhao L, Means A, Henderson E, Matsuoka TA, Stein R. The islet beta cell-enriched RIPE3b1/Maf transcription factor regulates pdx-1 expression. The Journal of Biological Chemistry. 278: 12263-70. PMID 12551916 DOI: 10.1074/Jbc.M210801200  0.212
1998 Qiu YI, Sharma A, Stein R. p300 Mediates Transcriptional Stimulation by the Basic Helix-Loop-Helix Activators of the Insulin Gene Molecular and Cellular Biology. 18: 2957-2964. PMID 9566915 DOI: 10.1128/Mcb.18.5.2957  0.212
2011 Hunter CS, Maestro MA, Raum JC, Guo M, Thompson FH, Ferrer J, Stein R. Hnf1α (MODY3) regulates β-cell-enriched MafA transcription factor expression. Molecular Endocrinology (Baltimore, Md.). 25: 339-47. PMID 21193557 DOI: 10.1210/Me.2010-0362  0.21
2011 Pound LD, Hang Y, Sarkar SA, Wang Y, Milam LA, Oeser JK, Printz RL, Lee CE, Stein R, Hutton JC, O'Brien RM. The pancreatic islet β-cell-enriched transcription factor Pdx-1 regulates Slc30a8 gene transcription through an intronic enhancer. The Biochemical Journal. 433: 95-105. PMID 20942803 DOI: 10.1042/Bj20101488  0.209
1997 Peshavaria M, Henderson E, Sharma A, Wright CVE, Stein R. Functional Characterization of the Transactivation Properties of the PDX-1 Homeodomain Protein Molecular and Cellular Biology. 17: 3987-3996. PMID 9199333 DOI: 10.1128/Mcb.17.7.3987  0.205
2016 Yang YP, Magnuson MA, Stein R, Wright CV. The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine-cell specification and postnatal β-cell maturation. Development (Cambridge, England). PMID 27993987 DOI: 10.1242/Dev.143123  0.204
2017 Spaeth JM, Gupte M, Perelis M, Yang YP, Cyphert H, Guo S, Liu JH, Guo M, Bass J, Magnuson MA, Wright C, Stein R. Defining a Novel Role for the PDX1 Transcription Factor in Islet β Cell Maturation and Proliferation During Weaning. Diabetes. PMID 28705881 DOI: 10.2337/Db16-1516  0.204
2013 Hunter CS, Dixit S, Cohen T, Ediger B, Wilcox C, Ferreira M, Westphal H, Stein R, May CL. Islet α-, β-, and δ-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor. Diabetes. 62: 875-86. PMID 23193182 DOI: 10.2337/Db12-0952  0.204
2020 Russell R, Carnese PP, Hennings TG, Walker EM, Russ HA, Liu JS, Giacometti S, Stein R, Hebrok M. Loss of the transcription factor MAFB limits β-cell derivation from human PSCs. Nature Communications. 11: 2742. PMID 32488111 DOI: 10.1038/S41467-020-16550-9  0.203
2009 Fernandez-Zapico ME, van Velkinburgh JC, Gutiérrez-Aguilar R, Neve B, Froguel P, Urrutia R, Stein R. MODY7 gene, KLF11, is a novel p300-dependent regulator of Pdx-1 (MODY4) transcription in pancreatic islet beta cells. The Journal of Biological Chemistry. 284: 36482-90. PMID 19843526 DOI: 10.1074/Jbc.M109.028852  0.203
2004 Le Lay J, Matsuoka TA, Henderson E, Stein R. Identification of a novel PDX-1 binding site in the human insulin gene enhancer. The Journal of Biological Chemistry. 279: 22228-35. PMID 15028719 DOI: 10.1074/Jbc.M312673200  0.201
1989 Whelan J, Poon D, Weil PA, Stein R. Pancreatic beta-cell-type-specific expression of the rat insulin II gene is controlled by positive and negative cellular transcriptional elements. Molecular and Cellular Biology. 9: 3253-3259. PMID 2552288 DOI: 10.1128/Mcb.9.8.3253  0.201
2009 Du A, Hunter CS, Murray J, Noble D, Cai CL, Evans SM, Stein R, May CL. Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas. Diabetes. 58: 2059-69. PMID 19502415 DOI: 10.2337/Db08-0987  0.201
2017 Hunter CS, Stein RW. Evidence for Loss in Identity, De-Differentiation, and Trans-Differentiation of Islet β-Cells in Type 2 Diabetes. Frontiers in Genetics. 8: 35. PMID 28424732 DOI: 10.3389/fgene.2017.00035  0.201
1990 Whelan J, Cordle SR, Henderson E, Weil PA, Stein R. Identification of a pancreatic beta-cell insulin gene transcription factor that binds to and appears to activate cell-type-specific expression: its possible relationship to other cellular factors that bind to a common insulin gene sequence. Molecular and Cellular Biology. 10: 1564-1572. PMID 2181278 DOI: 10.1128/Mcb.10.4.1564  0.2
2015 Scoville DW, Cyphert HA, Liao L, Xu J, Reynolds A, Guo S, Stein R. MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function. Diabetes. 64: 3772-83. PMID 26180087 DOI: 10.2337/Db15-0281  0.2
2007 Artner I, Blanchi B, Raum JC, Guo M, Kaneko T, Cordes S, Sieweke M, Stein R. MafB is required for islet beta cell maturation. Proceedings of the National Academy of Sciences of the United States of America. 104: 3853-8. PMID 17360442 DOI: 10.1073/Pnas.0700013104  0.2
2011 Hang Y, Stein R. MafA and MafB activity in pancreatic β cells. Trends in Endocrinology and Metabolism: Tem. 22: 364-73. PMID 21719305 DOI: 10.1016/J.Tem.2011.05.003  0.198
1994 Peshavaria M, Gamer L, Henderson E, Teitelman G, Wright CV, Stein R. XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor. Molecular Endocrinology (Baltimore, Md.). 8: 806-16. PMID 7935494 DOI: 10.1210/Mend.8.6.7935494  0.198
2014 Hang Y, Yamamoto T, Benninger RK, Brissova M, Guo M, Bush W, Piston DW, Powers AC, Magnuson M, Thurmond DC, Stein R. The MafA transcription factor becomes essential to islet β-cells soon after birth. Diabetes. 63: 1994-2005. PMID 24520122 DOI: 10.2337/Db13-1001  0.197
2008 Artner I, Hang Y, Guo M, Gu G, Stein R. MafA is a dedicated activator of the insulin gene in vivo. The Journal of Endocrinology. 198: 271-9. PMID 18515495 DOI: 10.1677/Joe-08-0063  0.197
2011 Chen C, Chai J, Singh L, Kuo CY, Jin L, Feng T, Marzano S, Galeni S, Zhang N, Iacovino M, Qin L, Hara M, Stein R, Bromberg JS, Kyba M, et al. Characterization of an in vitro differentiation assay for pancreatic-like cell development from murine embryonic stem cells: detailed gene expression analysis. Assay and Drug Development Technologies. 9: 403-19. PMID 21395400 DOI: 10.1089/Adt.2010.0314  0.197
2016 Ediger BN, Lim HW, Juliana C, Groff DN, Williams LT, Dominguez G, Liu JH, Taylor BL, Walp ER, Kameswaran V, Yang J, Liu C, Hunter CS, Kaestner KH, Naji A, ... ... Stein R, et al. LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells. The Journal of Clinical Investigation. PMID 27941246 DOI: 10.1172/Jci88016  0.194
2000 Peshavaria M, Cissell MA, Henderson E, Petersen HV, Stein R. The PDX-1 activation domain provides specific functions necessary for transcriptional stimulation in pancreatic beta-cells. Molecular Endocrinology. 14: 1907-1917. PMID 11117522 DOI: 10.1210/Mend.14.12.0563  0.194
2006 Boyer DF, Fujitani Y, Gannon M, Powers AC, Stein RW, Wright CV. Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression. Developmental Biology. 298: 616-31. PMID 16962573 DOI: 10.1016/J.Ydbio.2006.07.020  0.194
2011 Liu J, Hunter CS, Du A, Ediger B, Walp E, Murray J, Stein R, May CL. Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development. The Journal of Biological Chemistry. 286: 15352-60. PMID 21388963 DOI: 10.1074/Jbc.M111.231670  0.192
1991 Cordle SR, Whelan J, Henderson E, Masuoka H, Weil PA, Stein R. Insulin gene expression in nonexpressing cells appears to be regulated by multiple distinct negative-acting control elements. Molecular and Cellular Biology. 11: 2881-2886. PMID 2017182 DOI: 10.1128/Mcb.11.5.2881  0.19
2014 Stahnke MJ, Dickel C, Schröder S, Kaiser D, Blume R, Stein R, Pouponnot C, Oetjen E. Inhibition of human insulin gene transcription and MafA transcriptional activity by the dual leucine zipper kinase. Cellular Signalling. 26: 1792-9. PMID 24726898 DOI: 10.1016/J.Cellsig.2014.04.006  0.189
2000 Gerrish K, Gannon M, Shih D, Henderson E, Stoffel M, Wright CV, Stein R. Pancreatic beta cell-specific transcription of the pdx-1 gene. The role of conserved upstream control regions and their hepatic nuclear factor 3beta sites. The Journal of Biological Chemistry. 275: 3485-92. PMID 10652343 DOI: 10.1074/Jbc.275.5.3485  0.189
2003 Cissell MA, Zhao L, Sussel L, Henderson E, Stein R. Transcription factor occupancy of the insulin gene in vivo. Evidence for direct regulation by Nkx2.2. The Journal of Biological Chemistry. 278: 751-6. PMID 12426319 DOI: 10.1074/Jbc.M205905200  0.188
1994 Robinson GL, Cordle SR, Henderson E, Weil PA, Teitelman G, Stein R. Isolation and characterization of a novel transcription factor that binds to and activates insulin control element-mediated expression. Molecular and Cellular Biology. 14: 6704-14. PMID 7935390 DOI: 10.1128/Mcb.14.10.6704  0.188
1991 Cordle SR, Henderson E, Masuoka H, Weil PA, Stein R. Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins. Molecular and Cellular Biology. 11: 1734-1738. PMID 1996119 DOI: 10.1128/Mcb.11.3.1734  0.188
2005 Harmon JS, Stein R, Robertson RP. Oxidative stress-mediated, post-translational loss of MafA protein as a contributing mechanism to loss of insulin gene expression in glucotoxic beta cells. The Journal of Biological Chemistry. 280: 11107-13. PMID 15664999 DOI: 10.1074/Jbc.M410345200  0.187
2010 Artner I, Hang Y, Mazur M, Yamamoto T, Guo M, Lindner J, Magnuson MA, Stein R. MafA and MafB regulate genes critical to beta-cells in a unique temporal manner. Diabetes. 59: 2530-9. PMID 20627934 DOI: 10.2337/Db10-0190  0.186
2011 Stein R. Insulin Gene Transcription: Factors Involved in Cell Type–Specific and Glucose-Regulated Expression in Islet β Cells are Also Essential During Pancreatic Development Comprehensive Physiology. 25-47. DOI: 10.1002/Cphy.Cp070202  0.186
2004 Gerrish K, Van Velkinburgh JC, Stein R. Conserved transcriptional regulatory domains of the pdx-1 gene. Molecular Endocrinology (Baltimore, Md.). 18: 533-48. PMID 14701942 DOI: 10.1210/Me.2003-0371  0.186
2006 Tweedie E, Artner I, Crawford L, Poffenberger G, Thorens B, Stein R, Powers AC, Gannon M. Maintenance of hepatic nuclear factor 6 in postnatal islets impairs terminal differentiation and function of beta-cells. Diabetes. 55: 3264-70. PMID 17130469 DOI: 10.2337/Db06-0090  0.185
2015 Matsuoka TA, Kaneto H, Kawashima S, Miyatsuka T, Tochino Y, Yoshikawa A, Imagawa A, Miyazaki J, Gannon M, Stein R, Shimomura I. Preserving Mafa expression in diabetic islet β-cells improves glycemic control in vivo. The Journal of Biological Chemistry. 290: 7647-57. PMID 25645923 DOI: 10.1074/Jbc.M114.595579  0.185
2015 McKenna B, Guo M, Reynolds A, Hara M, Stein R. Dynamic recruitment of functionally distinct Swi/Snf chromatin remodeling complexes modulates Pdx1 activity in islet β cells. Cell Reports. 10: 2032-42. PMID 25801033 DOI: 10.1016/J.Celrep.2015.02.054  0.184
2006 Ueki K, Okada T, Hu J, Liew CW, Assmann A, Dahlgren GM, Peters JL, Shackman JG, Zhang M, Artner I, Satin LS, Stein R, Holzenberger M, Kennedy RT, Kahn CR, et al. Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes. Nature Genetics. 38: 583-8. PMID 16642022 DOI: 10.1038/Ng1787  0.184
1997 Fernandes A, King LC, Guz Y, Stein R, Wright CVE, Teitelman G. Differentiation of New Insulin-Producing Cells Is Induced by Injury in Adult Pancreatic Islets Endocrinology. 138: 1750-1762. PMID 9075740 DOI: 10.1210/Endo.138.4.5049  0.184
2007 Wiebe PO, Kormish JD, Roper VT, Fujitani Y, Alston NI, Zaret KS, Wright CV, Stein RW, Gannon M. Ptf1a binds to and activates area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression. Molecular and Cellular Biology. 27: 4093-104. PMID 17403901 DOI: 10.1128/Mcb.01978-06  0.183
2016 Spaeth JM, Walker EM, Stein R. Impact of Pdx1-associated chromatin modifiers on islet β-cells. Diabetes, Obesity & Metabolism. 18: 123-7. PMID 27615141 DOI: 10.1111/Dom.12730  0.183
2014 Conrad E, Stein R, Hunter CS. Revealing transcription factors during human pancreatic β cell development. Trends in Endocrinology and Metabolism: Tem. 25: 407-14. PMID 24831984 DOI: 10.1016/J.Tem.2014.03.013  0.182
1989 Stein RW, Whelan J. Insulin gene enhancer activity is inhibited by adenovirus 5 E1a gene products. Molecular and Cellular Biology. 9: 4531-4. PMID 2531280  0.182
1997 Sharma A, Henderson E, Gamer L, Zhuang Y, Stein R. Analysis of the Role of E2A-Encoded Proteins in Insulin Gene Transcription Molecular Endocrinology. 11: 1608-1617. PMID 9328343 DOI: 10.1210/Mend.11.11.0004  0.181
2004 Matsuoka TA, Artner I, Henderson E, Means A, Sander M, Stein R. The MafA transcription factor appears to be responsible for tissue-specific expression of insulin. Proceedings of the National Academy of Sciences of the United States of America. 101: 2930-3. PMID 14973194 DOI: 10.1073/Pnas.0306233101  0.181
2003 Matsuoka TA, Zhao L, Artner I, Jarrett HW, Friedman D, Means A, Stein R. Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells. Molecular and Cellular Biology. 23: 6049-62. PMID 12917329 DOI: 10.1128/Mcb.23.17.6049-6062.2003  0.18
1996 Offield MF, Jetton TL, Labosky PA, Ray M, Stein RW, Magnuson MA, Hogan BL, Wright CV. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development (Cambridge, England). 122: 983-95. PMID 8631275  0.18
1994 Sharma A, Stein R. Glucose-induced transcription of the insulin gene is mediated by factors required for beta-cell-type-specific expression. Molecular and Cellular Biology. 14: 871-879. PMID 8289826 DOI: 10.1128/Mcb.14.2.871  0.179
2006 Poitout V, Hagman D, Stein R, Artner I, Robertson RP, Harmon JS. Regulation of the insulin gene by glucose and fatty acids. The Journal of Nutrition. 136: 873-6. PMID 16549443 DOI: 10.1093/Jn/136.4.873  0.178
2015 Spaeth JM, Hunter CS, Bonatakis L, Guo M, French CA, Slack I, Hara M, Fisher SE, Ferrer J, Morrisey EE, Stanger BZ, Stein R. The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice. Diabetologia. PMID 26021489 DOI: 10.1007/S00125-015-3635-3  0.178
2009 Stein R. Regulation of insulin gene transcription. Trends in Endocrinology and Metabolism: Tem. 4: 96-101. PMID 18407141 DOI: 10.1016/1043-2760(93)90086-T  0.178
2006 Le Lay J, Stein R. Involvement of PDX-1 in activation of human insulin gene transcription. The Journal of Endocrinology. 188: 287-94. PMID 16461554 DOI: 10.1677/Joe.1.06510  0.177
1997 Wu K, Gannon M, Peshavaria M, Offield MF, Henderson E, Ray M, Marks A, Gamer LW, Wright CVE, Stein R. Hepatocyte nuclear factor 3beta is involved in pancreatic beta-cell-specific transcription of the pdx-1 gene. Molecular and Cellular Biology. 17: 6002-6013. PMID 9315659 DOI: 10.1128/Mcb.17.10.6002  0.177
2003 Martin CC, Svitek CA, Oeser JK, Henderson E, Stein R, O'Brien RM. Upstream stimulatory factor (USF) and neurogenic differentiation/beta-cell E box transactivator 2 (NeuroD/BETA2) contribute to islet-specific glucose-6-phosphatase catalytic-subunit-related protein (IGRP) gene expression. The Biochemical Journal. 371: 675-86. PMID 12540293 DOI: 10.1042/Bj20021585  0.177
2011 Tsunekawa S, Demozay D, Briaud I, McCuaig J, Accili D, Stein R, Rhodes CJ. FoxO feedback control of basal IRS-2 expression in pancreatic β-cells is distinct from that in hepatocytes. Diabetes. 60: 2883-91. PMID 21933986 DOI: 10.2337/Db11-0340  0.177
2002 Samaras SE, Cissell MA, Gerrish K, Wright CV, Gannon M, Stein R. Conserved sequences in a tissue-specific regulatory region of the pdx-1 gene mediate transcription in Pancreatic beta cells: role for hepatocyte nuclear factor 3 beta and Pax6. Molecular and Cellular Biology. 22: 4702-13. PMID 12052878 DOI: 10.1128/Mcb.22.13.4702-4713.2002  0.177
2012 Dai C, Brissova M, Hang Y, Thompson C, Poffenberger G, Shostak A, Chen Z, Stein R, Powers AC. Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets. Diabetologia. 55: 707-18. PMID 22167125 DOI: 10.1007/S00125-011-2369-0  0.176
2014 Ediger BN, Du A, Liu J, Hunter CS, Walp ER, Schug J, Kaestner KH, Stein R, Stoffers DA, May CL. Islet-1 Is essential for pancreatic β-cell function. Diabetes. 63: 4206-17. PMID 25028525 DOI: 10.2337/Db14-0096  0.176
2006 Artner I, Le Lay J, Hang Y, Elghazi L, Schisler JC, Henderson E, Sosa-Pineda B, Stein R. MafB: an activator of the glucagon gene expressed in developing islet alpha- and beta-cells. Diabetes. 55: 297-304. PMID 16443760 DOI: 10.2337/Diabetes.55.02.06.Db05-0946  0.176
1994 Henderson E, Stein R. c-jun inhibits transcriptional activation by the insulin enhancer, and the insulin control element is the target of control. Molecular and Cellular Biology. 14: 655-662. PMID 8264634 DOI: 10.1128/Mcb.14.1.655  0.175
2009 Ogihara T, Vanderford NL, Maier B, Stein RW, Mirmira RG. Expression and function of Set7/9 in pancreatic islets. Islets. 1: 269-72. PMID 21099283 DOI: 10.4161/Isl.1.3.9779  0.175
2013 Guo S, Dai C, Guo M, Taylor B, Harmon JS, Sander M, Robertson RP, Powers AC, Stein R. Inactivation of specific β cell transcription factors in type 2 diabetes. The Journal of Clinical Investigation. 123: 3305-16. PMID 23863625 DOI: 10.1172/Jci65390  0.174
2009 Pechhold S, Stouffer M, Walker G, Martel R, Seligmann B, Hang Y, Stein R, Harlan DM, Pechhold K. Transcriptional analysis of intracytoplasmically stained, FACS-purified cells by high-throughput, quantitative nuclease protection. Nature Biotechnology. 27: 1038-42. PMID 19838197 DOI: 10.1038/Nbt.1579  0.174
2006 Raum JC, Gerrish K, Artner I, Henderson E, Guo M, Sussel L, Schisler JC, Newgard CB, Stein R. FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site. Molecular and Cellular Biology. 26: 5735-43. PMID 16847327 DOI: 10.1128/Mcb.00249-06  0.174
1995 Sharma A, Olson LK, Robertson RP, Stein R. The reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to high glucose concentration is associated with the loss of RIPE3b1 and STF-1 transcription factor expression. Molecular Endocrinology. 9: 1127-1134. PMID 7491105 DOI: 10.1210/Mend.9.9.7491105  0.174
1987 Stein RW, Ziff EB. Repression of insulin gene expression by adenovirus type 5 E1a proteins. Molecular and Cellular Biology. 7: 1164-70. PMID 2951590  0.174
1995 Olson LK, Sharma A, Peshavaria M, Wright CVE, Towle HC, Robertson RP, Stein R. Reduction of insulin gene transcription in HIT-T15 β cells chronically exposed to a supraphysiologic glucose concentration is associated with loss of STF-1 transcription factor expression Proceedings of the National Academy of Sciences of the United States of America. 92: 9127-9131. PMID 7568086 DOI: 10.1073/Pnas.92.20.9127  0.173
2015 Paul L, Walker EM, Drosos Y, Cyphert HA, Neale G, Stein R, South J, Grosveld G, Herrera PL, Sosa-Pineda B. Lack of Prox1 Downregulation Disrupts the Expansion and Maturation of Postnatal Murine β-cells. Diabetes. PMID 26631740 DOI: 10.2337/Db15-0713  0.173
2008 Vanhoose AM, Samaras S, Artner I, Henderson E, Hang Y, Stein R. MafA and MafB regulate Pdx1 transcription through the Area II control region in pancreatic beta cells. The Journal of Biological Chemistry. 283: 22612-9. PMID 18522939 DOI: 10.1074/Jbc.M802902200  0.173
2015 Maganti AV, Maier B, Tersey SA, Sampley ML, Mosley AL, Özcan S, Pachaiyappan B, Woster PM, Hunter CS, Stein R, Mirmira RG. Transcriptional activity of the islet β cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9. The Journal of Biological Chemistry. 290: 9812-22. PMID 25713082 DOI: 10.1074/Jbc.M114.616219  0.172
1994 Stein R, Henderson E, Cordle SR. Analysis of an insulin gene transcription control element: Positive and negative regulation appears to be mediated by different element sequences Febs Letters. 338: 187-190. PMID 8307179 DOI: 10.1016/0014-5793(94)80362-5  0.171
2005 Zhao L, Guo M, Matsuoka TA, Hagman DK, Parazzoli SD, Poitout V, Stein R. The islet beta cell-enriched MafA activator is a key regulator of insulin gene transcription. The Journal of Biological Chemistry. 280: 11887-94. PMID 15665000 DOI: 10.1074/Jbc.M409475200  0.171
2011 Schwab K, Neumann B, Vignon-Zellweger N, Fischer A, Stein R, Jungblut PR, Scheler C, Theuring F. Dietary phytoestrogen supplementation induces sex differences in the myocardial protein pattern of mice: a comparative proteomics study. Proteomics. 11: 3887-904. PMID 21800425 DOI: 10.1002/pmic.201000785  0.17
2013 Hunter CS, Stein R. Characterization of an apparently novel β-cell line-enriched 80-88 kDa transcriptional activator of the MafA and Pdx1 genes. The Journal of Biological Chemistry. 288: 3795-803. PMID 23269676 DOI: 10.1074/Jbc.M112.434282  0.17
2007 Matsuoka TA, Kaneto H, Stein R, Miyatsuka T, Kawamori D, Henderson E, Kojima I, Matsuhisa M, Hori M, Yamasaki Y. MafA regulates expression of genes important to islet beta-cell function. Molecular Endocrinology (Baltimore, Md.). 21: 2764-74. PMID 17636040 DOI: 10.1210/Me.2007-0028  0.169
2002 Qiu Y, Guo M, Huang S, Stein R. Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47. Molecular and Cellular Biology. 22: 412-20. PMID 11756538 DOI: 10.1128/Mcb.22.2.412-420.2002  0.169
2001 Gerrish K, Cissell MA, Stein R. The role of hepatic nuclear factor 1 alpha and PDX-1 in transcriptional regulation of the pdx-1 gene. The Journal of Biological Chemistry. 276: 47775-84. PMID 11590182 DOI: 10.1074/Jbc.M109244200  0.169
2020 Coate KC, Cha J, Shrestha S, Wang W, Gonçalves LM, Almaça J, Kapp ME, Fasolino M, Morgan A, Dai C, Saunders DC, Bottino R, Aramandla R, Jenkins R, Stein R, et al. SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 are Expressed in the Pancreas but are Not Enriched in Islet Endocrine Cells. Biorxiv : the Preprint Server For Biology. PMID 33106804 DOI: 10.1101/2020.08.31.275719  0.169
2018 Haliyur R, Tong X, Sanyoura M, Shrestha S, Lindner J, Saunders DC, Aramandla R, Poffenberger G, Redick SD, Bottino R, Prasad N, Levy SE, Blind RD, Harlan DM, Philipson LH, ... Stein RW, et al. Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks. The Journal of Clinical Investigation. PMID 30507613 DOI: 10.1172/Jci121994  0.168
2014 Gao T, McKenna B, Li C, Reichert M, Nguyen J, Singh T, Yang C, Pannikar A, Doliba N, Zhang T, Stoffers DA, Edlund H, Matschinsky F, Stein R, Stanger BZ. Pdx1 maintains β cell identity and function by repressing an α cell program. Cell Metabolism. 19: 259-71. PMID 24506867 DOI: 10.1016/J.Cmet.2013.12.002  0.166
2016 Dai C, Kayton NS, Shostak A, Poffenberger G, Cyphert HA, Aramandla R, Thompson C, Papagiannis IG, Emfinger C, Shiota M, Stafford JM, Greiner DL, Herrera PL, Shultz LD, Stein R, et al. Stress-impaired transcription factor expression and insulin secretion in transplanted human islets. The Journal of Clinical Investigation. PMID 27064285 DOI: 10.1172/Jci83657  0.166
1997 Carty MD, Lillquist JS, Peshavaria M, Stein R, Soeller WC. Identification of cis- and trans-active factors regulating human islet amyloid polypeptide gene expression in pancreatic beta-cells. Journal of Biological Chemistry. 272: 11986-11993. PMID 9115263 DOI: 10.1074/Jbc.272.18.11986  0.165
2003 Moates JM, Nanda S, Cissell MA, Tsai MJ, Stein R. BETA2 activates transcription from the upstream glucokinase gene promoter in islet beta-cells and gut endocrine cells. Diabetes. 52: 403-8. PMID 12540614 DOI: 10.2337/Diabetes.52.2.403  0.165
2013 Stein RW, Williams TD. Extreme intraclutch egg-size dimorphism in Eudyptes penguins, an evolutionary response to clutch-size maladaptation. The American Naturalist. 182: 260-70. PMID 23852359 DOI: 10.1086/670929  0.164
2019 Tong X, Dai C, Walker JT, Nair GG, Kennedy A, Carr RM, Hebrok M, Powers AC, Stein R. Lipid Droplet Accumulation in Human Pancreatic Islets is Dependent Upon Both Donor Age and Health. Diabetes. PMID 31836690 DOI: 10.2337/Db19-0281  0.163
2020 Coate KC, Cha J, Shrestha S, Wang W, Gonçalves LM, Almaça J, Kapp ME, Fasolino M, Morgan A, Dai C, Saunders DC, Bottino R, Aramandla R, Jenkins R, Stein R, et al. SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells. Cell Metabolism. PMID 33207245 DOI: 10.1016/j.cmet.2020.11.006  0.163
2015 Conrad E, Dai C, Spaeth J, Guo M, Cyphert HA, Scoville D, Carroll J, Yu WM, Goodrich LV, Harlan DM, Grove KL, Roberts CT, Powers AC, Gu G, Stein R. The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00285.2015. PMID 26554594 DOI: 10.1152/Ajpendo.00285.2015  0.162
2018 Huang C, Walker EM, Dadi PK, Hu R, Xu Y, Zhang W, Sanavia T, Mun J, Liu J, Nair GG, Tan HYA, Wang S, Magnuson MA, Stoeckert CJ, Hebrok M, ... ... Stein R, et al. Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca Sensitivity of Insulin Secretion Vesicles. Developmental Cell. PMID 29656931 DOI: 10.1016/J.Devcel.2018.03.013  0.161
2010 Matsuoka TA, Kaneto H, Miyatsuka T, Yamamoto T, Yamamoto K, Kato K, Shimomura I, Stein R, Matsuhisa M. Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes. Diabetes. 59: 1709-20. PMID 20424231 DOI: 10.2337/Db08-0693  0.161
2018 Brissova M, Haliyur R, Saunders D, Shrestha S, Dai C, Blodgett DM, Bottino R, Campbell-Thompson M, Aramandla R, Poffenberger G, Lindner J, Pan FC, von Herrath MG, Greiner DL, Shultz LD, ... ... Stein R, et al. α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes. Cell Reports. 22: 2667-2676. PMID 29514095 DOI: 10.1016/J.Celrep.2018.02.032  0.159
2011 Bonnefond A, Lomberk G, Buttar N, Busiah K, Vaillant E, Lobbens S, Yengo L, Dechaume A, Mignot B, Simon A, Scharfmann R, Neve B, Tanyolaç S, Hodoglugil U, Pattou F, ... ... Stein R, et al. Disruption of a novel Kruppel-like transcription factor p300-regulated pathway for insulin biosynthesis revealed by studies of the c.-331 INS mutation found in neonatal diabetes mellitus. The Journal of Biological Chemistry. 286: 28414-24. PMID 21592955 DOI: 10.1074/Jbc.M110.215822  0.158
2005 Kitamura YI, Kitamura T, Kruse JP, Raum JC, Stein R, Gu W, Accili D. FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction. Cell Metabolism. 2: 153-63. PMID 16154098 DOI: 10.1016/J.Cmet.2005.08.004  0.158
2004 Qiu Y, Guo M, Huang S, Stein R. Acetylation of the BETA2 transcription factor by p300-associated factor is important in insulin gene expression. The Journal of Biological Chemistry. 279: 9796-802. PMID 14701848 DOI: 10.1074/jbc.M307577200  0.157
2012 Yan L, Guo S, Brault M, Harmon J, Robertson RP, Hamid R, Stein R, Yang E. The B55α-containing PP2A holoenzyme dephosphorylates FOXO1 in islet β-cells under oxidative stress. The Biochemical Journal. 444: 239-47. PMID 22417654 DOI: 10.1042/Bj20111606  0.157
2018 Iacovazzo D, Flanagan SE, Walker E, Quezado R, de Sousa Barros FA, Caswell R, Johnson MB, Wakeling M, Brändle M, Guo M, Dang MN, Gabrovska P, Niederle B, Christ E, Jenni S, ... ... Stein R, et al. MAFA missense mutation causes familial insulinomatosis and diabetes mellitus. Proceedings of the National Academy of Sciences of the United States of America. PMID 29339498 DOI: 10.1073/Pnas.1712262115  0.156
1995 Sharma A, Fusco-DeMane D, Henderson E, Efrat S, Stein R. The role of the insulin control element and RIPE3b1 activators in glucose-stimulated transcription of the insulin gene. Molecular Endocrinology. 9: 1468-1476. PMID 8584024 DOI: 10.1210/Mend.9.11.8584024  0.156
2017 Matsuoka TA, Kawashima S, Miyatsuka T, Sasaki S, Shimo N, Katakami N, Kawamori D, Takebe S, Herrera PL, Kaneto H, Stein R, Shimomura I. Mafa Enables Pdx1 to Effectively Convert Pancreatic Islet Progenitors and Committed Islet α-Cells into β-Cells in Vivo. Diabetes. PMID 28223284 DOI: 10.2337/Db16-0887  0.156
2001 Matsuoka T, Zhao L, Stein R. The DNA binding activity of the RIPE3b1 transcription factor of insulin appears to be influenced by tyrosine phosphorylation. Journal of Biological Chemistry. 276: 22071-22076. PMID 11309378 DOI: 10.1074/Jbc.M010321200  0.155
2005 Van Velkinburgh JC, Samaras SE, Gerrish K, Artner I, Stein R. Interactions between areas I and II direct pdx-1 expression specifically to islet cell types of the mature and developing pancreas. The Journal of Biological Chemistry. 280: 38438-44. PMID 16147997 DOI: 10.1074/Jbc.M508594200  0.153
2007 Oetjen E, Blume R, Cierny I, Schlag C, Kutschenko A, Krätzner R, Stein R, Knepel W. Inhibition of MafA transcriptional activity and human insulin gene transcription by interleukin-1β and mitogen-activated protein kinase kinase kinase in pancreatic islet beta cells Diabetologia. 50: 1678-1687. PMID 17583797 DOI: 10.1007/S00125-007-0712-2  0.153
1999 Huang S, Qiu Y, Stein RW, Brandt SJ. p300 functions as a transcriptional coactivator for the TAL1/SCL oncoprotein. Oncogene. 18: 4958-67. PMID 10490830 DOI: 10.1038/Sj.Onc.1202889  0.152
2000 Zhao L, Cissell MA, Henderson E, Colbran R, Stein R. The RIPE3b1 activator of the insulin gene is composed of a protein(s) of approximately 43 kDa, whose DNA binding activity is inhibited by protein phosphatase treatment Journal of Biological Chemistry. 275: 10532-10537. PMID 10744746 DOI: 10.1074/Jbc.275.14.10532  0.151
2019 Wilson CS, Spaeth JM, Karp J, Stocks BT, Hoopes EM, Stein RW, Moore DJ. B lymphocytes protect islet β cells in diabetes prone NOD mice treated with imatinib. Jci Insight. 5. PMID 30964447 DOI: 10.1172/Jci.Insight.125317  0.151
2018 Cyphert HA, Walker EM, Hang Y, Dhawan S, Haliyur R, Bonatakis L, Avrahami D, Brissova M, Kaestner KH, Bhushan A, Powers AC, Stein R. "Examining How the MAFB Transcription Factor Affects Islet β Cell Function Postnatally". Diabetes. PMID 30425060 DOI: 10.2337/Db18-0903  0.151
1998 Petersen HV, Peshavaria M, Pedersen AA, Philippe J, Stein R, Madsen OD, Serup P. Glucose stimulates the activation domain potential of the PDX-1 homeodomain transcription factor. Febs Letters. 431: 362-366. PMID 9714543 DOI: 10.1016/S0014-5793(98)00776-5  0.149
2002 Petersen HV, Jensen JN, Stein R, Serup P. Glucose induced MAPK signalling influences NeuroD1-mediated activation and nuclear localization. Febs Letters. 528: 241-5. PMID 12297313 DOI: 10.1016/S0014-5793(02)03318-5  0.147
2020 Hu R, Walker E, Huang C, Xu Y, Weng C, Erickson GE, Coldren A, Yang X, Brissova M, Kaverina I, Appakalai BN, Wright CVE, Li Y, Stein R, Gu G. Myt Transcription Factors Prevent Stress-Response Gene Overactivation to Enable Postnatal Pancreatic β Cell Proliferation, Function, and Survival. Developmental Cell. PMID 32359405 DOI: 10.1016/J.Devcel.2020.04.003  0.146
2019 Prentice BM, Hart NJ, Phillips N, Haliyur R, Judd A, Armandala R, Spraggins JM, Lowe CL, Boyd KL, Stein RW, Wright CV, Norris JL, Powers AC, Brissova M, Caprioli RM. Imaging mass spectrometry enables molecular profiling of mouse and human pancreatic tissue. Diabetologia. PMID 30955045 DOI: 10.1007/S00125-019-4855-8  0.145
2020 Hu R, Walker E, Huang C, Xu Y, Weng C, Erickson GE, Coldren A, Yang X, Brissova M, Kaverina I, Balamurugan AN, Wright CVE, Li Y, Stein R, Gu G. Myt Transcription Factors Prevent Stress-Response Gene Overactivation to Enable Postnatal Pancreatic β Cell Proliferation, Function, and Survival. Developmental Cell. 53: 754. PMID 32574594 DOI: 10.1016/j.devcel.2020.06.007  0.142
2011 Hunter C, Cohen T, Ediger B, Wilcox C, Dixit S, Westphal H, Stein R, May C. The LIM co-factor Ldb1 is enriched in pancreatic islet cells and required for proper cell development and function Developmental Biology. 356: 240-241. DOI: 10.1016/J.Ydbio.2011.05.424  0.142
2020 Tellez K, Hang Y, Gu X, Chang CA, Stein RW, Kim SK. In vivo studies of glucagon secretion by human islets transplanted in mice. Nature Metabolism. 2: 547-557. PMID 32694729 DOI: 10.1038/s42255-020-0213-x  0.141
1994 Robinson G, Peshavaria M, Henderson E, Shieh S, Tsai M, Teitelman G, Stein R. Expression of the trans-active factors that stimulate insulin control element-mediated activity appear to precede insulin gene transcription. Journal of Biological Chemistry. 269: 2452-2460. DOI: 10.1016/s0021-9258(17)41967-3  0.139
2015 Zhu X, Hu R, Brissova M, Stein RW, Powers AC, Gu G, Kaverina I. Microtubules Negatively Regulate Insulin Secretion in Pancreatic β Cells. Developmental Cell. 34: 656-68. PMID 26418295 DOI: 10.1016/j.devcel.2015.08.020  0.138
1995 Robinson GLWG, Henderson E, Massari ME, Murre C, Stein R. c-Jun inhibits insulin control element-mediated transcription by affecting the transactivation potential of the E2A gene products Molecular and Cellular Biology. 15: 1398-1404. PMID 7862133 DOI: 10.1128/Mcb.15.3.1398  0.134
2017 Dean ED, Li M, Prasad N, Wisniewski SN, Von Deylen A, Spaeth J, Maddison L, Botros A, Sedgeman LR, Bozadjieva N, Ilkayeva O, Coldren A, Poffenberger G, Shostak A, Semich MC, ... ... Stein R, et al. Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation. Cell Metabolism. 25: 1362-1373.e5. PMID 28591638 DOI: 10.1016/J.Cmet.2017.05.011  0.133
2016 Banerjee RR, Cyphert HA, Walker EM, Chakravarthy H, Peiris H, Gu X, Liu Y, Conrad E, Goodrich L, Stein RW, Kim SK. Gestational diabetes from inactivation of prolactin receptor and MafB in islet β-cells. Diabetes. PMID 27217483 DOI: 10.2337/Db15-1527  0.131
1991 Hicks BA, Stein R, Efrat S, Grant S, Hanahan D, Demetriou AA. Transplantation of beta cells from transgenic mice into nude athymic diabetic rats restores glucose regulation. Diabetes Research and Clinical Practice. 14: 157-64. PMID 1778108 DOI: 10.1016/0168-8227(91)90016-7  0.13
2002 Shih DQ, Heimesaat M, Kuwajima S, Stein R, Wright CV, Stoffel M. Profound defects in pancreatic beta-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1alpha, and Hnf-3beta. Proceedings of the National Academy of Sciences of the United States of America. 99: 3818-23. PMID 11904435 DOI: 10.1073/Pnas.062605899  0.129
2005 Kim JB, Stein R, O'Hare MJ. Tumour-stromal interactions in breast cancer: the role of stroma in tumourigenesis. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 26: 173-85. PMID 16006771 DOI: 10.1159/000086950  0.127
1984 Stein R, Ziff EB. HeLa cell beta-tubulin gene transcription is stimulated by adenovirus 5 in parallel with viral early genes by an E1a-dependent mechanism. Molecular and Cellular Biology. 4: 2792-2801. DOI: 10.1128/MCB.4.12.2792  0.127
1991 Pietenpol JA, Münger K, Howley PM, Stein RW, Moses HL. Factor-binding element in the human c-myc promoter involved in transcriptional regulation by transforming growth factor beta 1 and by the retinoblastoma gene product. Proceedings of the National Academy of Sciences of the United States of America. 88: 10227-31. PMID 1946442 DOI: 10.1073/Pnas.88.22.10227  0.126
2010 Zhu L, Zhao G, Stein R, Zheng X, Hu W, Shang N, Bu X, Liu X, Wang J, Feng E, Wang B, Zhang X, Ye Q, Huang P, Zeng M, et al. The proteome of Shigella flexneri 2a 2457T grown at 30 and 37 degrees C. Molecular & Cellular Proteomics : McP. 9: 1209-20. PMID 20164057 DOI: 10.1074/mcp.M900446-MCP200  0.124
2003 Griffin D, Penberthy WT, Lum H, Stein RW, Taylor WL. Isolation of the B3 transcription factor of the Xenopus TFIIIA gene. Gene. 313: 179-88. PMID 12957389 DOI: 10.1016/S0378-1119(03)00678-4  0.123
2010 Raum JC, Hunter CS, Artner I, Henderson E, Guo M, Elghazi L, Sosa-Pineda B, Ogihara T, Mirmira RG, Sussel L, Stein R. Islet β-cell-specific MafA transcription requires the 5′-Flanking conserved region 3 control domain Molecular and Cellular Biology. 30: 4234-4244. PMID 20584984 DOI: 10.1128/Mcb.01396-09  0.122
2020 Wokoma OS, Tong X, Dai C, Powers AC, Stein R. Species-Specific Effects of Fatty Acid-Dependent Lipid Droplet Homeostasis within Pancreatic Islet β cells Metabolism. 104: 154085. DOI: 10.1016/J.Metabol.2019.12.031  0.121
1995 German M, Ashcroft S, Docherty K, Edlund H, Edlund T, Goodison S, Imura H, Kennedy G, Madsen O, Melloul D, Moss L, Olson K, Permutt MA, Philippe J, Robertson RP, ... ... Stein R, et al. The insulin gene promoter: A simplified nomenclature Diabetes. 44: 1002-1004. PMID 7621988 DOI: 10.2337/diab.44.8.1002  0.121
2023 Hammel MC, Stein R, Kratzsch J, Vogel M, Eckert AJ, Triatin RD, Colombo M, Meigen C, Baber R, Stanik J, Spielau U, Stoltze A, Wirkner K, Tönjes A, Snieder H, et al. Fasting indices of glucose-insulin-metabolism across life span and prediction of glycemic deterioration in children with obesity from new diagnostic cut-offs. The Lancet Regional Health. Europe. 30: 100652. PMID 37465325 DOI: 10.1016/j.lanepe.2023.100652  0.119
2006 Fujitani Y, Fujitani S, Boyer DF, Gannon M, Kawaguchi Y, Ray M, Shiota M, Stein RW, Magnuson MA, Wright CV. Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation. Genes & Development. 20: 253-66. PMID 16418487 DOI: 10.1101/Gad.1360106  0.119
2022 Kempf E, Landgraf K, Stein R, Hanschkow M, Hilbert A, Abou Jamra R, Boczki P, Herberth G, Kühnapfel A, Tseng YH, Stäubert C, Schöneberg T, Kühnen P, Rayner NW, Zeggini E, et al. Aberrant expression of agouti signaling protein (ASIP) as a cause of monogenic severe childhood obesity. Nature Metabolism. 4: 1697-1712. PMID 36536132 DOI: 10.1038/s42255-022-00703-9  0.118
2023 Stein R, Koutny F, Riedel J, Dörr N, Meyer K, Colombo M, Vogel M, Anderwald CH, Blüher M, Kiess W, Körner A, Weghuber D. Single Point Insulin Sensitivity Estimator (SPISE) As a Prognostic Marker for Emerging Dysglycemia in Children with Overweight or Obesity. Metabolites. 13. PMID 36677025 DOI: 10.3390/metabo13010100  0.117
1990 Pietenpol JA, Holt JT, Stein RW, Moses HL. Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation. Proceedings of the National Academy of Sciences of the United States of America. 87: 3758-62. PMID 2187192 DOI: 10.1073/Pnas.87.10.3758  0.116
2021 Kim SY, Colaiacovo S, Dave S, Coughlin K, Langdon K, Stein R, Saleh M. Aromatase deficiency in an Ontario Old Order Mennonite family. Journal of Pediatric Endocrinology & Metabolism : Jpem. PMID 34348419 DOI: 10.1515/jpem-2021-0229  0.115
2009 Guo S, Burnette R, Zhao L, Vanderford NL, Poitout V, Hagman DK, Henderson E, Ozcan S, Wadzinski BE, Stein R. The stability and transactivation potential of the mammalian MafA transcription factor are regulated by serine 65 phosphorylation. The Journal of Biological Chemistry. 284: 759-65. PMID 19004825 DOI: 10.1074/Jbc.M806314200  0.114
2013 Thiede B, Koehler CJ, Strozynski M, Treumann A, Stein R, Zimny-Arndt U, Schmid M, Jungblut PR. High resolution quantitative proteomics of HeLa cells protein species using stable isotope labeling with amino acids in cell culture(SILAC), two-dimensional gel electrophoresis(2DE) and nano-liquid chromatograpohy coupled to an LTQ-OrbitrapMass spectrometer. Molecular & Cellular Proteomics : McP. 12: 529-38. PMID 23033477 DOI: 10.1074/mcp.M112.019372  0.11
2005 Stein RW, Place AR, Lacourse T, Guglielmo CG, Williams TD. Digestive organ sizes and enzyme activities of refueling western sandpipers (Calidris mauri): contrasting effects of season and age. Physiological and Biochemical Zoology : Pbz. 78: 434-46. PMID 15887090 DOI: 10.1086/430038  0.11
1990 Stein RW, Corrigan M, Yaciuk P, Whelan J, Moran E. Analysis of E1A-mediated growth regulation functions: binding of the 300-kilodalton cellular product correlates with E1A enhancer repression function and DNA synthesis-inducing activity. Journal of Virology. 64: 4421-7. PMID 2143544 DOI: 10.1128/Jvi.64.9.4421-4427.1990  0.11
2022 Kempf E, Landgraf K, Vogel T, Spielau U, Stein R, Raschpichler M, Kratzsch J, Kiess W, Stanik J, Körner A. Associations of and expression in adipose tissue cells with obesity-related alterations in corresponding circulating levels and adipose tissue function in children. Adipocyte. 11: 630-642. PMID 36384443 DOI: 10.1080/21623945.2022.2148886  0.11
2012 Nagano K, Akpan A, Warnasuriya G, Corless S, Totty N, Yang A, Stein R, Zvelebil M, Stensballe A, Burlingame A, Waterfield M, Cramer R, Timms JF, Naaby-Hansen S. Functional proteomic analysis of long-term growth factor stimulation and receptor tyrosine kinase coactivation in Swiss 3T3 fibroblasts. Molecular & Cellular Proteomics : McP. 11: 1690-708. PMID 22956732 DOI: 10.1074/Mcp.M112.019778  0.109
2008 Stein RW, Fernández G, De La Cueva H, Elner RW. Disproportionate bill length dimorphism and niche differentiation in wintering western sandpipers (Calidris mauri) Canadian Journal of Zoology. 86: 601-609. DOI: 10.1139/Z08-033  0.109
2010 Guo S, Vanderford NL, Stein R. Phosphorylation within the MafA N terminus regulates C-terminal dimerization and DNA binding. The Journal of Biological Chemistry. 285: 12655-61. PMID 20208071 DOI: 10.1074/Jbc.M110.105759  0.108
1990 Pietenpol JA, Stein RW, Moran E, Yaciuk P, Schlegel R, Lyons RM, Pittelkow MR, Münger K, Howley PM, Moses HL. TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains. Cell. 61: 777-85. PMID 2140528 DOI: 10.1016/0092-8674(90)90188-K  0.106
2014 Lange S, Rosenkrands I, Stein R, Andersen P, Kaufmann SH, Jungblut PR. Analysis of protein species differentiation among mycobacterial low-Mr-secreted proteins by narrow pH range Immobiline gel 2-DE-MALDI-MS. Journal of Proteomics. 97: 235-44. PMID 23856608 DOI: 10.1016/j.jprot.2013.06.036  0.106
2016 Stein R, Kapplusch F, Heymann MC, Russ S, Staroske W, Hedrich CM, Rösen-Wolff A, Hofmann SR. Enzymatically inactive procaspase-1 stabilizes the ASC-pyroptosome and supports pyroptosome spreading during cell division. The Journal of Biological Chemistry. PMID 27402835 DOI: 10.1074/jbc.M116.718668  0.106
2007 Wiebe PO, Kormish JD, Fujitani Y, Zaret KS, Wright CV, Stein RW, Gannon. Ptf1a binds to Area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression Developmental Biology. 306: 353-354. DOI: 10.1016/J.Ydbio.2007.03.225  0.105
2013 Shiff NJ, Brant R, Guzman J, Cabral DA, Huber AM, Miettunen P, Roth J, Scuccimarri R, Alos N, Atkinson SA, Collet JP, Couch R, Cummings EA, Dent PB, Ellsworth J, ... ... Stein R, et al. Glucocorticoid-related changes in body mass index among children and adolescents with rheumatic diseases. Arthritis Care & Research. 65: 113-21. PMID 22826190 DOI: 10.1002/Acr.21785  0.105
2023 Stein R, Göpel E, Weghuber D, Hammel MC, Vogel M, Kiess W, Körner A. Are there relevant thresholds of insulin-independent indices across the lifespan to predict alterations in glycemic control?-Authors' reply. The Lancet Regional Health. Europe. 33: 100734. PMID 37701043 DOI: 10.1016/j.lanepe.2023.100734  0.103
2008 Hoehenwarter W, Tang Y, Ackermann R, Pleissner KP, Schmid M, Stein R, Zimny-Arndt U, Kumar NM, Jungblut PR. Identification of proteins that modify cataract of mouse eye lens Proteomics. 8: 5011-5024. PMID 19003866 DOI: 10.1002/pmic.200800380  0.1
2014 Winston K, Stein R. Mixed germ cell tumour after testotoxicosis Clinical Endocrinology. 81: 786-787. PMID 24467671 DOI: 10.1111/cen.12416  0.099
2008 Lee JS, Krause R, Schreiber J, Mollenkopf HJ, Kowall J, Stein R, Jeon BY, Kwak JY, Song MK, Patron JP, Jorg S, Roh K, Cho SN, Kaufmann SH. Mutation in the transcriptional regulator PhoP contributes to avirulence of Mycobacterium tuberculosis H37Ra strain. Cell Host & Microbe. 3: 97-103. PMID 18312844 DOI: 10.1016/J.Chom.2008.01.002  0.099
2015 Buckingham BA, Raghinaru D, Cameron F, Bequette BW, Chase HP, Maahs DM, Slover R, Wadwa RP, Wilson DM, Ly T, Aye T, Hramiak I, Clarson C, Stein R, Gallego PH, et al. Erratum. Predictive Low-Glucose Insulin Suspension Reduces Duration of Nocturnal Hypoglycemia in Children Without Increasing Ketosis. Diabetes Care 2015;38:1197-1204. Diabetes Care. 38: 1813. PMID 26294776 DOI: 10.2337/Dc15-Er09  0.097
2023 Ma J, Siminoski K, Jaremko JL, Koujok K, Matzinger MA, Shenouda N, Wilson N, Cheng M, Alos N, Atkinson S, Cummings EA, Ho J, Rodd C, Sbrocchi AM, Stein R, et al. Vertebral body reshaping after fractures: an important index of recovery in glucocorticoid-treated children. The Journal of Clinical Endocrinology and Metabolism. PMID 37843393 DOI: 10.1210/clinem/dgad611  0.097
2004 Kim JB, Stein R, O'Hare MJ. Three-dimensional in vitro tissue culture models of breast cancer-- a review. Breast Cancer Research and Treatment. 85: 281-91. PMID 15111767 DOI: 10.1023/B:BREA.0000025418.88785.2b  0.095
2021 Hanschkow M, Boulet N, Kempf E, Bouloumié A, Kiess W, Stein R, Körner A, Landgraf K. Expression of the adipocyte progenitor markers MSCA1 and CD36 is associated with adipose tissue function in children. The Journal of Clinical Endocrinology and Metabolism. PMID 34448000 DOI: 10.1210/clinem/dgab630  0.093
2015 Buckingham BA, Raghinaru D, Cameron F, Bequette BW, Chase HP, Maahs DM, Slover R, Wadwa RP, Wilson DM, Ly T, Aye T, Hramiak I, Clarson C, Stein R, Gallego PH, et al. Predictive Low-Glucose Insulin Suspension Reduces Duration of Nocturnal Hypoglycemia in Children Without Increasing Ketosis. Diabetes Care. 38: 1197-204. PMID 26049549 DOI: 10.2337/Dc14-3053  0.092
2015 Rosolowsky ET, Stein R, Marks SD, Leonard N. Marked phenotypic variable expression among brothers with duplication of Xq27.1 involving the SOX3 gene. Journal of Pediatric Endocrinology & Metabolism : Jpem. PMID 26352083 DOI: 10.1515/jpem-2015-0131  0.09
2018 Waight JD, Chand D, Dietrich S, Gombos R, Horn T, Gonzalez AM, Manrique M, Swiech L, Morin B, Brittsan C, Tanne A, Akpeng B, Croker BA, Buell JS, Stein R, et al. Selective FcγR Co-engagement on APCs Modulates the Activity of Therapeutic Antibodies Targeting T Cell Antigens. Cancer Cell. 33: 1033-1047.e5. PMID 29894690 DOI: 10.1016/J.Ccell.2018.05.005  0.09
2016 Ganic E, Singh T, Luan C, Fadista J, Johansson JK, Cyphert HA, Bennet H, Storm P, Prost G, Ahlenius H, Renström E, Stein R, Groop L, Fex M, Artner I. MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes Cell Reports. 14: 1991-2002. DOI: 10.1016/j.celrep.2016.02.002  0.089
1995 Stoffel M, Stein R, Wright CV, Espinosa R, Le Beau MM, Bell GI. Localization of human homeodomain transcription factor insulin promoter factor 1 (IPF1) to chromosome band 13q12.1. Genomics. 28: 125-6. PMID 7590740 DOI: 10.1006/Geno.1995.1120  0.089
2004 Cockburn BN, Bermano G, Boodram LL, Teelucksingh S, Tsuchiya T, Mahabir D, Allan AB, Stein R, Docherty K, Bell GI. Insulin promoter factor-1 mutations and diabetes in Trinidad: identification of a novel diabetes-associated mutation (E224K) in an Indo-Trinidadian family. The Journal of Clinical Endocrinology and Metabolism. 89: 971-8. PMID 14764823 DOI: 10.1210/Jc.2003-031282  0.087
2010 Jungblut PR, Schiele F, Zimny-Arndt U, Ackermann R, Schmid M, Lange S, Stein R, Pleissner KP. Helicobacter pylori proteomics by 2-DE/MS, 1-DE-LC/MS and functional data mining Proteomics. 10: 182-193. PMID 19941309 DOI: 10.1002/pmic.200900361  0.083
2020 Cha J, Walker EM, Tong X, Guo M, Liu JH, Yu S, Iacovazzo D, Mauvais-Jarvis F, Flanagan SE, Korbonits M, Stafford JM, Stein R. 2116-P: MAFA S64F Missense Mutation Causes Islet Beta-Cell Aging and Senescence Diabetes. 69. DOI: 10.2337/Db20-2116-P  0.083
2015 Heymann MC, Rabe S, Ruß S, Kapplusch F, Schulze F, Stein R, Winkler S, Hedrich CM, Rösen-Wolff A, Hofmann SR. Fluorescent tags influence the enzymatic activity and subcellular localization of procaspase-1. Clinical Immunology (Orlando, Fla.). 160: 172-9. PMID 26025004 DOI: 10.1016/j.clim.2015.05.011  0.082
2020 Berberich AJ, Wang J, Cao H, McIntyre AD, Spaic T, Miller DB, Stock S, Huot C, Stein R, Knoll J, Yang P, Robinson JF, Hegele RA. Simplifying Detection of Copy-Number Variations in Maturity-Onset Diabetes of the Young. Canadian Journal of Diabetes. PMID 33011132 DOI: 10.1016/j.jcjd.2020.06.001  0.082
2020 Bi H, Karanth SS, Ye K, Stein R, Jin S. Decellularized Tissue Matrix Enhances Self-Assembly of Islet Organoids from Pluripotent Stem Cell Differentiation Acs Biomaterials Science & Engineering. 6: 4155-4165. DOI: 10.1021/acsbiomaterials.0c00088  0.081
2019 Kapplusch F, Schulze F, Rabe-Matschewsky S, Russ S, Herbig M, Heymann MC, Schoepf K, Stein R, Range U, Rösen-Wolff A, Winkler S, Hedrich CM, Guck J, Hofmann SR. CASP1 variants influence subcellular caspase-1 localization, pyroptosome formation, pro-inflammatory cell death and macrophage deformability. Clinical Immunology (Orlando, Fla.). PMID 31252176 DOI: 10.1016/J.Clim.2019.06.008  0.08
2011 Holland C, Schmid M, Zimny-Arndt U, Rohloff J, Stein R, Jungblut PR, Meyer TF. Quantitative phosphoproteomics reveals link between Helicobacter pylori infection and RNA splicing modulation in host cells. Proteomics. 11: 2798-811. PMID 21717572 DOI: 10.1002/Pmic.201000793  0.08
2023 Ott R, Stein R, Hauta-Alus HH, Ronkainen J, Fernández-Barrés S, Spielau U, Kirsten H, Poulain T, Melton PE, Küpers LK, Azaryah H, Colombo M, Landgraf K, Tobi EW, O'Sullivan T, et al. Epigenome-Wide Meta-analysis Reveals Associations Between Dietary Glycemic Index and Glycemic Load and DNA Methylation in Children and Adolescents of Different Body Sizes. Diabetes Care. 46: 2067-2075. PMID 37756535 DOI: 10.2337/dc23-0474  0.08
2022 Kiess W, Stoltze A, Kirstein AS, Gesing J, Stein R, Körner A, Pfäffle R. Disorders of sex development - biologic, genetic, cultural, societal, and psychologic diversity of the human nature. Journal of Pediatric Endocrinology & Metabolism : Jpem. PMID 36480478 DOI: 10.1515/jpem-2022-0595  0.08
2018 Gombos RB, Gonzalez A, Manrique M, Chand D, Savitsky D, Morin B, Breous-Nystrom E, Dupont C, Ward RA, Mundt C, Duckless B, Tang H, Findeis MA, Schuster A, Waight JD, ... ... Stein R, et al. Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody. Plos One. 13: e0191926. PMID 29617360 DOI: 10.1371/Journal.Pone.0191926  0.079
2015 Loeffler M, Engel C, Ahnert P, Alfermann D, Arelin K, Baber R, Beutner F, Binder H, Brähler E, Burkhardt R, Ceglarek U, Enzenbach C, Fuchs M, Glaesmer H, Girlich F, ... ... Stein R, et al. The LIFE-Adult-Study: objectives and design of a population-based cohort study with 10,000 deeply phenotyped adults in Germany. Bmc Public Health. 15: 691. PMID 26197779 DOI: 10.1186/S12889-015-1983-Z  0.079
2009 Rashtak S, DeMars CJ, Lomberk GA, Stein R, Urrutia RA, Buttar N. M1747 Knockout of KLF11, a Tumor Suppressor for Pancreatic Cancer, Displays An Abnormal Glucose Metabolism Gastroenterology. 136: A-423. DOI: 10.1016/S0016-5085(09)61947-8  0.075
2022 Filler G, Tremblay O, Chen E, Huang SSH, Stein R. Sex differences of burosumab in children with X-linked hypophosphataemic rickets. Pediatric Nephrology (Berlin, Germany). PMID 36542147 DOI: 10.1007/s00467-022-05822-9  0.073
2008 Slaughter MS, Sobieski MA, Gallagher C, Graham J, Brandise J, Stein R. Fibrinolytic activation during long-term support with the HeartMate II left ventricular assist device. Asaio Journal (American Society For Artificial Internal Organs : 1992). 54: 115-9. PMID 18204326 DOI: 10.1097/MAT.0b013e318161a987  0.073
2006 Stein RW, Williams TD. Causes and consequences of post-growth age-dependent differences in small intestine size in a migratory sandpiper (Calidris mauri, Western Sandpiper) Functional Ecology. 20: 142-150. DOI: 10.1111/j.1365-2435.2006.01065.x  0.071
2023 Förster LJ, Vogel M, Stein R, Hilbert A, Breinker JL, Böttcher M, Kiess W, Poulain T. Mental health in children and adolescents with overweight or obesity. Bmc Public Health. 23: 135. PMID 36658514 DOI: 10.1186/s12889-023-15032-z  0.069
2011 Hartmann C, Hentschel B, Tatagiba M, Schramm J, Schnell O, Seidel C, Stein R, Reifenberger G, Pietsch T, von Deimling A, Loeffler M, Weller M. Molecular markers in low-grade gliomas: predictive or prognostic? Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4588-99. PMID 21558404 DOI: 10.1158/1078-0432.Ccr-10-3194  0.068
2020 Gam K, Frainey B, Zhang JH, Stein R. Surveillance of a Renal Mass in a Patient with ANCA-Negative Pauci-immune Glomerulonephritis: A Case Report. Urology. PMID 32289362 DOI: 10.1016/j.urology.2020.03.032  0.067
2015 LeBlanc CM, Ma J, Taljaard M, Roth J, Scuccimarri R, Miettunen P, Lang B, Huber AM, Houghton K, Jaremko JL, Ho J, Shenouda N, Matzinger MA, Lentle B, Stein R, et al. Incident Vertebral Fractures and Risk Factors in the First Three Years Following Glucocorticoid Initiation Among Pediatric Patients With Rheumatic Disorders. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 25801315 DOI: 10.1002/jbmr.2511  0.066
2019 Spaic T, Robinson T, Goldbloom E, Gallego P, Hramiak I, Lawson M, Malcolm J, Mahon J, Morrison D, Parikh A, Simone A, Stein R, Uvarov A, Clarson C. Closing the Gap: Results of the Multicenter Canadian Randomized Controlled Trial of Structured Transition in Young Adults With Type 1 Diabetes. Diabetes Care. PMID 31010873 DOI: 10.2337/dc18-2187  0.066
2012 Schwab K, Stein R, Scheler C, Theuring F. Dietary genistein enhances phosphorylation of regulatory myosin light chain in the myocardium of ovariectomized mice Electrophoresis. 33: 1795-1803. PMID 22740468 DOI: 10.1002/elps.201100607  0.063
2022 Phung K, McAdam L, Ma J, McMillan HJ, Jackowski S, Scharke M, Matzinger MA, Shenouda N, Koujok K, Jaremko JL, Smit K, Walker S, Hartigan C, Khan N, Konji VN, ... ... Stein R, et al. Risk factors associated with prevalent vertebral fractures in Duchenne muscular dystrophy. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. PMID 36342539 DOI: 10.1007/s00198-022-06578-6  0.062
2015 Jiménez JA, Zhang Z, Zhao J, Abouassaly R, Fergany A, Gong M, Kaouk J, Krishnamurthi V, Stein R, Stephenson A, Campbell SC. Surgical Salvage of Thermal Ablation Failures for Renal Cell Carcinoma. The Journal of Urology. PMID 26417642 DOI: 10.1016/j.juro.2015.09.078  0.062
2008 Allen JA, Stein R, Baker RA, Royden Jones H. Muscle atrophy associated with multiple sclerosis: a benign condition or the onset of amyotrophic lateral sclerosis? Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 15: 706-8. PMID 18395451 DOI: 10.1016/j.jocn.2007.04.024  0.061
2018 Ward LM, Ma J, Lang B, Ho J, Alos N, Matzinger MA, Shenouda N, Lentle B, Jaremko JL, Wilson B, Stephure D, Stein R, Sbrocchi AM, Rodd C, Lewis V, et al. Bone Morbidity and Recovery in Children With Acute Lymphoblastic Leukemia: Results of a Six-Year Prospective Cohort Study. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 29786884 DOI: 10.1002/jbmr.3447  0.061
2020 Hofmann SR, Girschick L, Stein R, Schulze F. Immune modulating effects of receptor interacting protein 2 (RIP2) in autoinflammation and immunity. Clinical Immunology (Orlando, Fla.). 223: 108648. PMID 33310070 DOI: 10.1016/j.clim.2020.108648  0.061
2018 Bertolo R, Garisto J, Dagenais J, Sagalovich D, Agudelo J, Stein R, Fareed K, Gao T, Fergany A, Kaouk J. cT1a renal masses < 2 versus > 2 cm managed with Robotic Partial Nephrectomy: a propensity-score matched comparison of perioperative Outcomes. The Journal of Urology. PMID 30100402 DOI: 10.1016/j.juro.2018.06.066  0.059
2020 Voigtmann F, Wolf P, Landgraf K, Stein R, Kratzsch J, Schmitz S, Jamra RA, Blüher M, Meiler J, Beck-Sickinger AG, Kiess W, Körner A. Identification of a novel leptin receptor (LEPR) variant and proof of functional relevance directing treatment decisions in patients with morbid obesity. Metabolism: Clinical and Experimental. 154438. PMID 33221380 DOI: 10.1016/j.metabol.2020.154438  0.059
1985 Stein RW, Papp AC, Weiner WJ, Wu KK. Reduction of serum prostacyclin stability in ischemic stroke. Stroke; a Journal of Cerebral Circulation. 16: 16-8. PMID 3880946 DOI: 10.1161/01.STR.16.1.16  0.055
2018 Garisto J, Bertolo R, Dagenais J, Sagalovich D, Fareed K, Fergany A, Stein R, Kaouk J. Robotic versus open partial nephrectomy for highly complex renal masses: Comparison of perioperative, functional, and oncological outcomes. Urologic Oncology. PMID 30100111 DOI: 10.1016/j.urolonc.2018.06.012  0.054
2014 Akca O, Zargar H, Autorino R, Brandao LF, Laydner H, Krishnan J, Samarasekera D, Li J, Haber GP, Stein R, Kaouk JH. Robotic partial nephrectomy for cystic renal masses: a comparative analysis of a matched-paired cohort. Urology. 84: 93-8. PMID 24821467 DOI: 10.1016/j.urology.2014.03.017  0.054
2009 Bui H, To T, Stein R, Fung K, Daneman D. Is diabetic ketoacidosis at disease onset a result of missed diagnosis? The Journal of Pediatrics. 156: 472-7. PMID 19962155 DOI: 10.1016/j.jpeds.2009.10.001  0.054
2004 Kim JB, O'Hare MJ, Stein R. Models of breast cancer: is merging human and animal models the future? Breast Cancer Research : Bcr. 6: 22-30. PMID 14680482 DOI: 10.1186/bcr645  0.054
2016 Malkoc E, Maurice MJ, Kara O, Ramirez D, Nelson RJ, Caputo PA, Mouracade P, Stein R, Kaouk JH. The Robotic Approach Improves Surgical Outcomes in Obese Patients Undergoing Partial Nephrectomy. Bju International. PMID 27699971 DOI: 10.1111/bju.13675  0.054
2023 Goobar A, Johansson J, Schulze S, Arendse N, Carracedo AS, Dhawan S, Mörtsell E, Fremling C, Yan L, Perley D, Sollerman J, Joseph R, Hinds KR, Meynardie W, Andreoni I, ... ... Stein R, et al. Uncovering a population of gravitational lens galaxies with magnified standard candle SN Zwicky. Nature Astronomy. 7: 1098-1107. PMID 37736027 DOI: 10.1038/s41550-023-01981-3  0.054
2012 Rane A, Stein R, Cadeddu J. Focal therapy for renal mass lesions: where do we stand in 2012? Bju International. 109: 491-2. PMID 22233234 DOI: 10.1111/j.1464-410X.2011.10855.x  0.054
2021 Ward LM, Ma J, Robinson ME, Scharke M, Ho J, Houghton K, Huber A, Scuccimarri R, Barsalou J, Roth J, Shenouda N, Matzinger MA, Lentle B, Jaremko JL, Koujok K, ... ... Stein R, et al. Osteoporotic Fractures and Vertebral Body Reshaping in Children with Glucocorticoid-Treated Rheumatic Disorders. The Journal of Clinical Endocrinology and Metabolism. PMID 34232311 DOI: 10.1210/clinem/dgab494  0.052
2017 Gonzalez Ballesteros LF, Ma NS, Gordon RJ, Ward L, Backeljauw P, Wasserman H, Weber DR, DiMeglio LA, Gagne J, Stein R, Cody D, Simmons K, Zimakas P, Topor LS, Agrawal S, et al. Unexpected and widespread hypophosphatemia and bone disease associated with elemental formula use in infants and children. Bone. PMID 28167344 DOI: 10.1016/j.bone.2017.02.003  0.051
1985 Kase CS, Robinson RK, Stein RW, DeWitt LD, Hier DB, Harp DL, Williams JP, Caplan LR, Mohr JP. Anticoagulant-related intracerebral hemorrhage. Neurology. 35: 943-8. PMID 4010961 DOI: 10.1212/Wnl.35.7.943  0.051
2022 Reusch S, Stein R, Kowalski M, van Velzen S, Franckowiak A, Lunardini C, Murase K, Winter W, Miller-Jones JCA, Kasliwal MM, Gilfanov M, Garrappa S, Paliya VS, Ahumada T, Anand S, et al. Candidate Tidal Disruption Event AT2019fdr Coincident with a High-Energy Neutrino. Physical Review Letters. 128: 221101. PMID 35714251 DOI: 10.1103/PhysRevLett.128.221101  0.051
2009 Desai MM, Stein R, Rao P, Canes D, Aron M, Rao PP, Haber GP, Fergany A, Kaouk J, Gill IS. Embryonic natural orifice transumbilical endoscopic surgery (E-NOTES) for advanced reconstruction: initial experience. Urology. 73: 182-7. PMID 18799203 DOI: 10.1016/j.urology.2008.04.061  0.048
2014 Rippy MA, Stein R, Sanders BF, Davis K, McLaughlin K, Skinner JF, Kappeler J, Grant SB. Small drains, big problems: the impact of dry weather runoff on shoreline water quality at enclosed beaches. Environmental Science & Technology. 48: 14168-77. PMID 25390647 DOI: 10.1021/Es503139H  0.048
2023 Körner A, Stein R, Landgraf K. Beyond genetic screening-functionality-based precision medicine in monogenic obesity. The Lancet. Diabetes & Endocrinology. 11: 143-144. PMID 36822741 DOI: 10.1016/S2213-8587(23)00031-1  0.046
2012 Rodd C, Lang B, Ramsay T, Alos N, Huber AM, Cabral DA, Scuccimarri R, Miettunen PM, Roth J, Atkinson SA, Couch R, Cummings EA, Dent PB, Ellsworth J, Hay J, ... ... Stein R, et al. Incident vertebral fractures among children with rheumatic disorders 12 months after glucocorticoid initiation: a national observational study. Arthritis Care & Research. 64: 122-31. PMID 22213727 DOI: 10.1002/acr.20589  0.046
2006 Semmler A, Stein RW, Caplan L, Danilov SM, Klockgether T, Linnebank M. Hereditary hyper-ACE-emia due to the Pro1199Leu mutation of somatic ACE as a potential pitfall in diagnosis: a first family outside Europe. Clinical Chemistry and Laboratory Medicine : Cclm / Fescc. 44: 1088-9. PMID 16958600 DOI: 10.1515/CCLM.2006.200  0.046
2023 Halton JM, Ma J, Babyn P, Matzinger MA, Kaste SC, Scharke M, Fernandez CV, Miettunen PM, Ho J, Alos N, Abish S, Barr R, Cairney E, Dix DB, Grant RM, ... ... Stein R, et al. Reductions in Bone Mineral Density are Apparent Early in Children with Prevalent Osteonecrosis Lesions Following Leukemia Therapy. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 37326443 DOI: 10.1002/jbmr.4870  0.046
1984 Stein RW, Kase CS, Hier DB, Caplan LR, Mohr JP, Hemmati M, Henderson K. Caudate hemorrhage. Neurology. 34: 1549-54. PMID 6504325 DOI: 10.1212/WNL.34.12.1549  0.044
2010 Irwin BH, Berger AK, Brandina R, Stein R, Desai MM. Complex percutaneous resections for upper-tract urothelial carcinoma. Journal of Endourology / Endourological Society. 24: 367-70. PMID 20218882 DOI: 10.1089/end.2009.0181  0.043
2015 Cummings EA, Ma J, Fernandez CV, Halton J, Alos N, Miettunen PM, Jaremko JL, Ho J, Shenouda N, Ann Matzinger M, Lentle B, Stephure D, Stein R, Marie Sbrocchi A, Rodd C, et al. Incident Vertebral Fractures in Children with Leukemia During the Four Years Following Diagnosis. The Journal of Clinical Endocrinology and Metabolism. JC20152176. PMID 26171800 DOI: 10.1210/JC.2015-2176  0.043
2020 Kahramangil B, Kose E, Remer EM, Reynolds JP, Stein R, Rini B, Siperstein A, Berber E. A Modern Assessment of Cancer Risk in Adrenal Incidentalomas: Analysis of 2219 Patients. Annals of Surgery. PMID 32541223 DOI: 10.1097/SLA.0000000000004048  0.042
2021 Marr A, Yokubynas N, Tang K, Saleh D, Wherrett DK, Stein R, Bassilious E, Chakraborty P, Lawrence SE. Transient Versus Permanent Congenital Hypothyroidism in Ontario, Canada: Predictive Factors and Scoring System. The Journal of Clinical Endocrinology and Metabolism. PMID 34726229 DOI: 10.1210/clinem/dgab798  0.042
2022 Filler G, Schott C, Salerno FR, Ens A, McIntyre CW, Díaz González de Ferris ME, Stein R. Growth hormone therapy in HHRH. Bone Reports. 16: 101591. PMID 35663378 DOI: 10.1016/j.bonr.2022.101591  0.042
2011 Stein R, Wherrett D, Daneman D. Management of 21-hydroxylase deficiency congenital adrenal hyperplasia: A survey of Canadian paediatric endocrinologists. Paediatrics & Child Health. 10: 323-6. PMID 19675839  0.041
2014 Goldberg AS, Stein R, Merritt NH, Inculet R, Van Uum S. A pediatric patient with Cushing syndrome caused by ectopic ACTH syndrome and concomitant pituitary incidentalomas. Journal of Pediatric Endocrinology & Metabolism : Jpem. 27: 123-8. PMID 23945121 DOI: 10.1515/jpem-2013-0070  0.041
2012 Alos N, Grant RM, Ramsay T, Halton J, Cummings EA, Miettunen PM, Abish S, Atkinson S, Barr R, Cabral DA, Cairney E, Couch R, Dix DB, Fernandez CV, Hay J, ... ... Stein R, et al. High incidence of vertebral fractures in children with acute lymphoblastic leukemia 12 months after the initiation of therapy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 2760-7. PMID 22734031 DOI: 10.1200/JCO.2011.40.4830  0.041
2020 Kortum P, Stein R, Acemyan CZ, Wallach DS, Vann E. How Human Factors Can Help Preserve Democracy in the Age of Pandemics. Human Factors. 18720820946896. PMID 32741224 DOI: 10.1177/0018720820946896  0.04
2003 Beshay M, Roth T, Stein R, Schmid RA. Synchronous bilateral typical pulmonary carcinoid tumors. European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association For Cardio-Thoracic Surgery. 23: 251-3. PMID 12559358 DOI: 10.1016/s1010-7940(02)00747-9  0.039
2018 Ma J, Siminoski K, Alos N, Halton J, Ho J, Cummings EA, Shenouda N, Matzinger MA, Lentle B, Jaremko JL, Wilson B, Stephure D, Stein R, Sbrocchi AM, Rodd C, et al. Impact of vertebral fractures and glucocorticoid exposure on height deficits in children during treatment for leukemia. The Journal of Clinical Endocrinology and Metabolism. PMID 30247635 DOI: 10.1210/jc.2018-01083  0.039
2018 Emamekhoo H, Dhillon P, Gopalakrishnan D, Elson P, Stephenson A, Magi-Galluzzi C, McKenney J, Harper H, Haber GP, Kaouk J, Lee B, Fergany A, Berglund R, Gong M, Stein R, et al. Prognostic Factors and Risk Stratification in Invasive Upper Tract Urothelial Carcinoma. Clinical Genitourinary Cancer. PMID 29551583 DOI: 10.1016/j.clgc.2018.01.014  0.038
2021 Koutny F, Stein R, Kiess W, Weghuber D, Körner A. Elevated transaminases potentiate the risk for emerging dysglycemia in children with overweight and obesity. Pediatric Obesity. e12822. PMID 34155821 DOI: 10.1111/ijpo.12822  0.037
2007 Davis DP, Graydon C, Stein R, Wilson S, Buesch B, Berthiaume S, Lee DM, Rivas J, Vilke GM, Leahy DR. The positive predictive value of paramedic versus emergency physician interpretation of the prehospital 12-lead electrocardiogram. Prehospital Emergency Care : Official Journal of the National Association of Ems Physicians and the National Association of State Ems Directors. 11: 399-402. PMID 17907023 DOI: 10.1080/10903120701536784  0.036
1978 Sausville EA, Stein RW, Peisach J, Horwitz SB. Properties and products of the degradation of DNA by bleomycin and iron(II). Biochemistry. 17: 2746-54. PMID 80227 DOI: 10.1021/Bi00607A008  0.035
2009 Desai MM, Berger AK, Brandina R, Aron M, Irwin BH, Canes D, Desai MR, Rao PP, Sotelo R, Stein R, Gill IS. Laparoendoscopic single-site surgery: initial hundred patients. Urology. 74: 805-12. PMID 19643465 DOI: 10.1016/j.urology.2009.02.083  0.035
1982 Klawans HL, Stein RW, Tanner CM, Goetz CG. A pure parkinsonian syndrome following acute carbon monoxide intoxication. Archives of Neurology. 39: 302-4. PMID 7073551 DOI: 10.1001/archneur.1982.00510170044012  0.035
2014 Mir MC, Takagi T, Campbell RA, Sharma N, Remer EM, Li J, Demirjian S, Stein R, Kaouk J, Campbell SC. Poorly functioning kidneys recover from ischemia after partial nephrectomy as well as strongly functioning kidneys Journal of Urology. 192: 665-670. PMID 24657801 DOI: 10.1016/j.juro.2014.03.036  0.034
2008 Kaouk JH, Hafron J, Parekattil S, Moinzadeh A, Stein R, Gill IS, Hegarty N. Is retroperitoneal approach feasible for robotic dismembered pyeloplasty: initial experience and long-term results. Journal of Endourology / Endourological Society. 22: 2153-9. PMID 18811572 DOI: 10.1089/end.2008.0130  0.034
2011 Hillyer SP, Autorino R, Laydner H, Yang B, Altunrende F, White M, Spana G, Khanna R, Isac W, Hernandez AV, Simmons M, Stein R, Haber GP, Kaouk J. Robotic versus laparoscopic partial nephrectomy for bilateral synchronous kidney tumors: single-institution comparative analysis. Urology. 78: 808-12. PMID 21855967 DOI: 10.1016/j.urology.2011.06.012  0.033
2016 Dunn JC, Buchanan GM, Stein RW, Whittingham MJ, McGowan PJK. Optimising different types of biodiversity coverage of protected areas with a case study using Himalayan Galliformes Biological Conservation. 196: 22-30. DOI: 10.1016/j.biocon.2016.01.015  0.032
2010 Stein R, Johnston I, Bannister S. Students completing a pediatric clinical clerkship in a regional center perform as well as their peers training at a university teaching hospital ... and they liked it better? Teaching and Learning in Medicine. 21: 225-8. PMID 20183342 DOI: 10.1080/10401330903018500  0.031
2013 Eccles SA, Aboagye EO, Ali S, Anderson AS, Armes J, Berditchevski F, Blaydes JP, Brennan K, Brown NJ, Bryant HE, Bundred NJ, Burchell JM, Campbell AM, Carroll JS, Clarke RB, ... ... Stein R, et al. Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast Cancer Research : Bcr. 15: R92. PMID 24286369 DOI: 10.1186/Bcr3493  0.031
2019 Bertolo R, Garisto J, Dagenais J, Sagalovich D, Stein R, Fareed K, Gao T, Armanyous S, Fergany A, Lioudis M, Kaouk J. Transperitoneal Robot-assisted Partial Nephrectomy with Minimum Follow-up of 5 Years: Oncological and Functional Outcomes from a Single Institution. European Urology Oncology. 2: 207-213. PMID 31017098 DOI: 10.1016/j.euo.2018.06.012  0.03
2022 Galler A, Röbl M, Prinz N, Dannemann A, Gellhaus I, Kapellen T, Linke S, Schauerte G, Stein R, Weghuber D, Weihrauch-Blüher S, Wiegand S, Holl R. Weight Development in Children and Adolescents with Obesity During the COVID-19 Pandemic. Deutsches Arzteblatt International. 119: 302-303. PMID 35912532 DOI: 10.3238/arztebl.m2022.0155  0.029
2018 Malkoç E, Maurice MJ, Akça O, Kara Ö, Zargar H, Andrade H, Ramirez D, Caputo P, Stein R, Sevag D, Kaouk JH. Significance of the nonneoplastic renal parenchymal findings in robotic partial nephrectomy series. Journal of Nephrology. PMID 29453652 DOI: 10.1007/s40620-018-0479-1  0.029
2004 Weber T, Roth TC, Beshay M, Herrmann P, Stein R, Schmid RA. Video-assisted thoracoscopic surgery of mediastinal bronchogenic cysts in adults: a single-center experience. The Annals of Thoracic Surgery. 78: 987-91. PMID 15337033 DOI: 10.1016/j.athoracsur.2004.03.092  0.029
2015 Caputo PA, Ko O, Patel R, Stein R. Robotic-assisted laparoscopic nephrectomy. Journal of Surgical Oncology. PMID 26352165 DOI: 10.1002/jso.24033  0.027
2016 Filler G, Ramsaroop A, Stein R, Grant C, Marants R, So A, McIntyre C. Is Testosterone Detrimental to Renal Function? Kidney International Reports. 1: 306-310. PMID 29318206 DOI: 10.1016/j.ekir.2016.07.004  0.025
2003 Stein RW, Williams TD. Tissue damage precludes the use of the everted sleeve technique to measure nutrient uptake in a small migratory shorebird, the western sandpiper (Calidris mauri). Physiological and Biochemical Zoology : Pbz. 76: 762-70. PMID 14671723 DOI: 10.1086/376426  0.025
2014 Brandao LF, Autorino R, Zargar H, Krishnan J, Laydner H, Akca O, Mir MC, Samarasekera D, Stein R, Kaouk J. Robot-assisted laparoscopic adrenalectomy: step-by-step technique and comparative outcomes. European Urology. 66: 898-905. PMID 24830625 DOI: 10.1016/j.eururo.2014.04.003  0.022
2018 Sagalovich D, Garisto J, Bertolo R, Yerram N, Dagenais J, Chavali JS, Haber GP, Kaouk J, Stein R. Minimally-Invasive Management of Ureteral Distal Strictures: Robotic Ureteroneocystostomy with a Bilateral Boari Flap. Urology. PMID 30077539 DOI: 10.1016/j.urology.2018.06.023  0.021
2008 Wang X, Yin L, Rao P, Stein R, Harsch KM, Lee Z, Heston WD. Targeted treatment of prostate cancer. Journal of Cellular Biochemistry. 102: 571-9. PMID 17685433 DOI: 10.1002/jcb.21491  0.021
2022 Kiess W, Kirstein AS, Stein R, Vogel M. Obesity after the Covid-19 pandemic and beyond. Journal of Pediatric Endocrinology & Metabolism : Jpem. 35: 135-138. PMID 35132847 DOI: 10.1515/jpem-2022-2135  0.017
2023 Benidir T, Lone Z, Wood A, Abdallah N, Campbell R, Bajic P, Purysko A, Nguyen JK, Kaouk J, Haber GP, Eltemamy M, Stein R, Haywood S, Klein EA, Almassi N, et al. Using IsoPSA with PI-RADS Score May Help Refine Biopsy Decision Making in Patients with Elevated PSA. Urology. PMID 36965817 DOI: 10.1016/j.urology.2023.03.014  0.016
2005 Hornstein SE, Stein R, Thompson D, Headly R, Dyer A. Questions analgesic protocols and conclusions of onychectomy study [3] Journal of the American Veterinary Medical Association. 227: 707. PMID 16178389  0.016
2021 Kappes C, Stein R, Körner A, Merkenschlager A, Kiess W. Stress, Stress Reduction and Obesity in Childhood and Adolescence. Hormone Research in Paediatrics. PMID 34469895 DOI: 10.1159/000519284  0.015
1998 Stein RW, Yamamoto JT, Fry DM, Wilson BW. Comparative hematology and plasma biochemistry of Red-tailed Hawks and American Kestrels wintering in California Journal of Raptor Research. 32: 163-169.  0.014
2008 Desai MM, Aron M, Berger A, Canes D, Stein R, Haber GP, Kamoi K, Crouzet S, Sotelo R, Gill IS. Transvesical robotic radical prostatectomy. Bju International. 102: 1666-9. PMID 18990136 DOI: 10.1111/j.1464-410X.2008.08004.x  0.014
2019 McKelvie B, Stein R. A lipemic blood sample in the paediatric critical care unit. Paediatrics & Child Health. 24: 10-11. PMID 30792592 DOI: 10.1093/pch/pxy086  0.013
2017 van den Bruck R, Weil PP, Ziegenhals T, Schreiner P, Juranek S, Gödde D, Vogel S, Schuster F, Orth V, Dörner J, Pembaur D, Röper M, Störkel S, Zirngibl H, Wirth S, ... ... Stein R, et al. Abstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016. Molecular and Cellular Pediatrics. 4: 5. PMID 28516419 DOI: 10.1186/S40348-017-0071-0  0.01
2014 Said A, Haddad RY, Stein R, Lerma EV. Thrombotic thrombocytopenic purpura. Disease-a-Month : Dm. 60: 500-4. PMID 25278278 DOI: 10.1016/j.disamonth.2014.08.005  0.01
2014 Akca O, Zargar H, Stein R. Editorial comment Urology. 83: 639. PMID 24387930 DOI: 10.1016/j.urology.2013.09.063  0.01
2008 Berkelhammer C, Mohammed A, Zalzaleh G, Grela J, Blumstein A, Stein R. Spontaneous multiperforation in lymphomatous colitis masquerading as Crohn's disease: 2 cases. Inflammatory Bowel Diseases. 14: 1172-3. PMID 18338762 DOI: 10.1002/ibd.20436  0.01
2008 Berkelhammer C, Patel N, Chen J, Sheth S, Stein R, Ambrose S. Hepatic infarction during pregnancy in catastrophic antiphospholipid syndrome. Journal of Gastroenterology and Hepatology. 22: 1695-6. PMID 17845701 DOI: 10.1111/j.1440-1746.2007.05129.x  0.01
2005 Zimmermann PG, Coombes NJ, Richmann J, Dolan B, Blucher V, Proebl JA, Stibal M, Murphy E, Parvis A, Feutral M, Pollack CV, Rowse P, Herr RD, Smith GA, Street J, ... ... Stein RW, et al. Cutting-edge discussions of management, policy, and program issues in emergency care Journal of Emergency Nursing. 31: 91-99. DOI: 10.1016/j.jen.2004.07.082  0.01
2000 Stein R. New laws for new technology. Aba Journal. 85: 92. PMID 11657445  0.01
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