Year |
Citation |
Score |
2024 |
Bankapalli K, Thomas RE, Vincow ES, Milstein G, Fisher LV, Pallanck LJ. A Drosophila model for mechanistic investigation of tau protein spread. Disease Models & Mechanisms. 17. PMID 39350752 DOI: 10.1242/dmm.050858 |
0.75 |
|
2024 |
Bankapalli K, Thomas RE, Vincow ES, Milstein G, Fisher LV, Pallanck LJ. A model for mechanistic investigation of tau protein spread. Biorxiv : the Preprint Server For Biology. PMID 38712083 DOI: 10.1101/2024.04.21.590466 |
0.745 |
|
2024 |
Sreejith P, Lolo S, Patten KR, Gunasinghe M, More N, Pallanck LJ, Bharadwaj R. Nazo, the Drosophila homolog of the NBIA-mutated protein-c19orf12, is required for triglyceride homeostasis. Plos Genetics. 20: e1011137. PMID 38335241 DOI: 10.1371/journal.pgen.1011137 |
0.308 |
|
2023 |
Vincow ES, Thomas RE, Milstein G, Pareek G, Bammler T, MacDonald J, Pallanck L. Glucocerebrosidase deficiency leads to neuropathology via cellular immune activation. Biorxiv : the Preprint Server For Biology. PMID 38168223 DOI: 10.1101/2023.12.13.571406 |
0.769 |
|
2021 |
Jewett KA, Thomas RE, Phan CQ, Lin B, Milstein G, Yu S, Bettcher LF, Neto FC, Djukovic D, Raftery D, Pallanck LJ, Davis MY. Glucocerebrosidase reduces the spread of protein aggregation in a Drosophila melanogaster model of neurodegeneration by regulating proteins trafficked by extracellular vesicles. Plos Genetics. 17: e1008859. PMID 33539341 DOI: 10.1371/journal.pgen.1008859 |
0.341 |
|
2021 |
Vincow ES, Thomas RE, Merrihew GE, MacCoss MJ, Pallanck LJ. Slowed protein turnover in aging Drosophila reflects a shift in cellular priorities. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 33453098 DOI: 10.1093/gerona/glab015 |
0.769 |
|
2020 |
Pareek G, Pallanck LJ. Inactivation of the mitochondrial protease Afg3l2 results in severely diminished respiratory chain activity and widespread defects in mitochondrial gene expression. Plos Genetics. 16: e1009118. PMID 33075064 DOI: 10.1371/journal.pgen.1009118 |
0.393 |
|
2019 |
Andreazza S, Samstag CL, Sanchez-Martinez A, Fernandez-Vizarra E, Gomez-Duran A, Lee JJ, Tufi R, Hipp MJ, Schmidt EK, Nicholls TJ, Gammage PA, Chinnery PF, Minczuk M, Pallanck LJ, Kennedy SR, et al. Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila. Nature Communications. 10: 3280. PMID 31337756 DOI: 10.1038/S41467-019-10857-Y |
0.594 |
|
2019 |
Vincow ES, Thomas RE, Merrihew G, Shulman NJ, Bammler TK, MacDonald JW, MacCoss MJ, Pallanck LJ. Autophagy accounts for approximately one-third of mitochondrial protein turnover and is protein selective. Autophagy. PMID 30865561 DOI: 10.1080/15548627.2019.1586258 |
0.775 |
|
2018 |
Pareek G, Pallanck LJ. Inactivation of Lon protease reveals a link between mitochondrial unfolded protein stress and mitochondrial translation inhibition. Cell Death & Disease. 9: 1168. PMID 30518747 DOI: 10.1038/s41419-018-1213-6 |
0.307 |
|
2018 |
Pareek G, Thomas RE, Vincow ES, Morris DR, Pallanck LJ. Lon protease inactivation in causes unfolded protein stress and inhibition of mitochondrial translation. Cell Death Discovery. 5: 51. PMID 30374414 DOI: 10.1038/S41420-018-0110-1 |
0.782 |
|
2018 |
Thomas RE, Vincow ES, Merrihew GE, MacCoss MJ, Davis MY, Pallanck LJ. Glucocerebrosidase deficiency promotes protein aggregation through dysregulation of extracellular vesicles. Plos Genetics. 14: e1007694. PMID 30256786 DOI: 10.1371/Journal.Pgen.1007694 |
0.805 |
|
2018 |
Pareek G, Thomas RE, Pallanck LJ. Loss of the Drosophila m-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration. Cell Death & Disease. 9: 304. PMID 29467464 DOI: 10.1038/s41419-018-0365-8 |
0.388 |
|
2017 |
Whitworth AJ, Pallanck LJ. PINK1/Parkin mitophagy and neurodegeneration-what do we really know in vivo? Current Opinion in Genetics & Development. 44: 47-53. PMID 28213158 DOI: 10.1016/j.gde.2017.01.016 |
0.544 |
|
2014 |
Thomas RE, Andrews LA, Burman JL, Lin WY, Pallanck LJ. PINK1-Parkin pathway activity is regulated by degradation of PINK1 in the mitochondrial matrix. Plos Genetics. 10: e1004279. PMID 24874806 DOI: 10.1371/journal.pgen.1004279 |
0.327 |
|
2013 |
Pallanck L. Mitophagy: mitofusin recruits a mitochondrial killer. Current Biology : Cb. 23: R570-2. PMID 23845246 DOI: 10.1016/j.cub.2013.05.032 |
0.382 |
|
2013 |
Vincow ES, Merrihew G, Thomas RE, Shulman NJ, Beyer RP, MacCoss MJ, Pallanck LJ. The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo. Proceedings of the National Academy of Sciences of the United States of America. 110: 6400-5. PMID 23509287 DOI: 10.1073/Pnas.1221132110 |
0.791 |
|
2013 |
Kim NC, Tresse E, Kolaitis RM, Molliex A, Thomas RE, Alami NH, Wang B, Joshi A, Smith RB, Ritson GP, Winborn BJ, Moore J, Lee JY, Yao TP, Pallanck L, et al. VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations. Neuron. 78: 65-80. PMID 23498974 DOI: 10.1016/J.Neuron.2013.02.029 |
0.454 |
|
2012 |
Hsieh EJ, Shulman NJ, Dai DF, Vincow ES, Karunadharma PP, Pallanck L, Rabinovitch PS, MacCoss MJ. Topograph, a software platform for precursor enrichment corrected global protein turnover measurements. Molecular & Cellular Proteomics : McP. 11: 1468-74. PMID 22865922 DOI: 10.1074/Mcp.O112.017699 |
0.759 |
|
2012 |
Burman JL, Yu S, Poole AC, Decal RB, Pallanck L. Analysis of neural subtypes reveals selective mitochondrial dysfunction in dopaminergic neurons from parkin mutants. Proceedings of the National Academy of Sciences of the United States of America. 109: 10438-43. PMID 22691499 DOI: 10.1073/Pnas.1120688109 |
0.733 |
|
2010 |
Chakrabarti L, Zahra R, Jackson SM, Kazemi-Esfarjani P, Sopher BL, Mason AG, Toneff T, Ryu S, Shaffer S, Kansy JW, Eng J, Merrihew G, MacCoss MJ, Murphy A, Goodlett DR, ... ... Pallanck LJ, et al. Mitochondrial dysfunction in NnaD mutant flies and Purkinje cell degeneration mice reveals a role for Nna proteins in neuronal bioenergetics. Neuron. 66: 835-47. PMID 20620870 DOI: 10.1016/J.Neuron.2010.05.024 |
0.323 |
|
2010 |
Poole AC, Thomas RE, Yu S, Vincow ES, Pallanck L. The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway. Plos One. 5: e10054. PMID 20383334 DOI: 10.1371/Journal.Pone.0010054 |
0.777 |
|
2009 |
Whitworth AJ, Pallanck LJ. The PINK1/Parkin pathway: a mitochondrial quality control system? Journal of Bioenergetics and Biomembranes. 41: 499-503. PMID 19967438 DOI: 10.1007/s10863-009-9253-3 |
0.578 |
|
2008 |
Whitworth AJ, Pallanck LJ. Genetic models of Parkinson's disease: mechanisms and therapies. Seb Experimental Biology Series. 60: 93-113. PMID 18309789 |
0.442 |
|
2008 |
Poole AC, Thomas RE, Andrews LA, McBride HM, Whitworth AJ, Pallanck LJ. The PINK1/Parkin pathway regulates mitochondrial morphology. Proceedings of the National Academy of Sciences of the United States of America. 105: 1638-43. PMID 18230723 DOI: 10.1073/Pnas.0709336105 |
0.775 |
|
2007 |
Voght SP, Fluegel ML, Andrews LA, Pallanck LJ. Drosophila NPC1b promotes an early step in sterol absorption from the midgut epithelium. Cell Metabolism. 5: 195-205. PMID 17339027 DOI: 10.1016/J.Cmet.2007.01.011 |
0.662 |
|
2006 |
Satterfield TF, Pallanck LJ. Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes. Human Molecular Genetics. 15: 2523-32. PMID 16835262 DOI: 10.1093/hmg/ddl173 |
0.684 |
|
2006 |
Pallanck L, Greenamyre JT. Neurodegenerative disease: pink, parkin and the brain. Nature. 441: 1058. PMID 16810237 DOI: 10.1038/4411058a |
0.382 |
|
2006 |
Whitworth AJ, Wes PD, Pallanck LJ. Drosophila models pioneer a new approach to drug discovery for Parkinson's disease. Drug Discovery Today. 11: 119-26. PMID 16533709 DOI: 10.1016/S1359-6446(05)03693-7 |
0.482 |
|
2006 |
Fluegel ML, Parker TJ, Pallanck LJ. Mutations of a Drosophila NPC1 gene confer sterol and ecdysone metabolic defects. Genetics. 172: 185-96. PMID 16079224 DOI: 10.1534/Genetics.105.046565 |
0.776 |
|
2005 |
Meulener M, Whitworth AJ, Armstrong-Gold CE, Rizzu P, Heutink P, Wes PD, Pallanck LJ, Bonini NM. Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease. Current Biology : Cb. 15: 1572-7. PMID 16139213 DOI: 10.1016/J.Cub.2005.07.064 |
0.497 |
|
2005 |
Whitworth AJ, Theodore DA, Greene JC, Benes H, Wes PD, Pallanck LJ. Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 8024-9. PMID 15911761 DOI: 10.1073/Pnas.0501078102 |
0.552 |
|
2005 |
Jackson SM, Whitworth AJ, Greene JC, Libby RT, Baccam SL, Pallanck LJ, La Spada AR. A SCA7 CAG/CTG repeat expansion is stable in Drosophila melanogaster despite modulation of genomic context and gene dosage. Gene. 347: 35-41. PMID 15715978 DOI: 10.1016/j.gene.2004.12.008 |
0.525 |
|
2005 |
Greene JC, Whitworth AJ, Andrews LA, Parker TJ, Pallanck LJ. Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis. Human Molecular Genetics. 14: 799-811. PMID 15689351 DOI: 10.1093/hmg/ddi074 |
0.58 |
|
2005 |
Pallanck LJ, Whitworth AJ. Drosophila models of parkinson disease Movement Disorders. 173-182. DOI: 10.1016/B978-012088382-0/50014-1 |
0.453 |
|
2004 |
Babcock M, Macleod GT, Leither J, Pallanck L. Genetic analysis of soluble N-ethylmaleimide-sensitive factor attachment protein function in Drosophila reveals positive and negative secretory roles. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3964-73. PMID 15102912 DOI: 10.1523/Jneurosci.5259-03.2004 |
0.768 |
|
2003 |
Babcock MC, Stowers RS, Leither J, Goodman CS, Pallanck LJ. A genetic screen for synaptic transmission mutants mapping to the right arm of chromosome 3 in Drosophila. Genetics. 165: 171-83. PMID 14504225 |
0.728 |
|
2003 |
Greene JC, Whitworth AJ, Kuo I, Andrews LA, Feany MB, Pallanck LJ. Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants. Proceedings of the National Academy of Sciences of the United States of America. 100: 4078-83. PMID 12642658 DOI: 10.1073/Pnas.0737556100 |
0.592 |
|
2002 |
Satterfield TF, Jackson SM, Pallanck LJ. A Drosophila homolog of the polyglutamine disease gene SCA2 is a dosage-sensitive regulator of actin filament formation. Genetics. 162: 1687-702. PMID 12524342 |
0.694 |
|
2001 |
Golby JA, Tolar LA, Pallanck L. Partitioning of N-ethylmaleimide-sensitive fusion (NSF) protein function in Drosophila melanogaster: dNSF1 is required in the nervous system, and dNSF2 is required in mesoderm. Genetics. 158: 265-78. PMID 11333235 |
0.802 |
|
1999 |
Littleton JT, Pallanck L, Ganetzky B. Mechanisms of neurotransmitter release. International Review of Neurobiology. 43: 139-61. PMID 10218158 |
0.469 |
|
1998 |
Tolar LA, Pallanck L. NSF function in neurotransmitter release involves rearrangement of the SNARE complex downstream of synaptic vesicle docking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 10250-6. PMID 9852562 DOI: 10.1523/Jneurosci.18-24-10250.1998 |
0.348 |
|
1995 |
McManus OB, Helms LM, Pallanck L, Ganetzky B, Swanson R, Leonard RJ. Functional role of the beta subunit of high conductance calcium-activated potassium channels. Neuron. 14: 645-50. PMID 7695911 DOI: 10.1016/0896-6273(95)90321-6 |
0.491 |
|
1995 |
Ganetzky B, Warmke JW, Robertson G, Pallanck L. New potassium channel gene families in flies and mammals: from mutants to molecules. Society of General Physiologists Series. 50: 29-39. PMID 7676322 |
0.763 |
|
1995 |
Pallanck L, Ordway RW, Ramaswami M, Chi WY, Krishnan KS, Ganetzky B. Distinct roles for N-ethylmaleimide-sensitive fusion protein (NSF) suggested by the identification of a second Drosophila NSF homolog. The Journal of Biological Chemistry. 270: 18742-4. PMID 7642522 DOI: 10.1074/Jbc.270.32.18742 |
0.765 |
|
1995 |
Pallanck L, Ordway RW, Ganetzky B. A Drosophila NSF mutant. Nature. 376: 25. PMID 7596428 DOI: 10.1038/376025a0 |
0.765 |
|
1994 |
Ordway RW, Pallanck L, Ganetzky B. Neurally expressed Drosophila genes encoding homologs of the NSF and SNAP secretory proteins. Proceedings of the National Academy of Sciences of the United States of America. 91: 5715-9. PMID 8202553 DOI: 10.1073/pnas.91.12.5715 |
0.783 |
|
1994 |
Pallanck L, Ganetzky B. Cloning and characterization of human and mouse homologs of the Drosophila calcium-activated potassium channel gene, slowpoke. Human Molecular Genetics. 3: 1239-43. PMID 7987297 DOI: 10.1093/Hmg/3.8.1239 |
0.527 |
|
1994 |
Ordway RW, Pallanck L, Ganetzky B. A TPR domain in the SNAP secretory proteins. Trends in Biochemical Sciences. 19: 530-1. PMID 7846761 DOI: 10.1016/0968-0004(94)90052-3 |
0.728 |
|
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