| Year |
Citation |
Score |
| 2024 |
Pullara F, Forsmann MC, General IJ, Ayoob JC, Furbee E, Castro SL, Hu X, Greenamyre JT, Di Maio R. NADPH oxidase 2 activity disrupts Calmodulin/CaMKIIα complex via redox modifications of CaMKIIα-contained Cys30 and Cys289: Implications in Parkinson's disease. Redox Biology. 75: 103254. PMID 38968922 DOI: 10.1016/j.redox.2024.103254 |
0.305 |
|
| 2024 |
Keeney MT, Hoffman EK, Weir J, Wagner WG, Rocha EM, Castro S, Farmer K, Fazzari M, Di Maio R, Konradi A, Hastings TG, Pintchovski SA, Shrader WD, Greenamyre JT. 15-Lipoxygenase-Mediated Lipid Peroxidation Regulates LRRK2 Kinase Activity. Biorxiv : the Preprint Server For Biology. PMID 38915558 DOI: 10.1101/2024.06.12.598654 |
0.559 |
|
| 2024 |
Ilieva NM, Hoffman EK, Ghalib MA, Greenamyre JT, De Miranda BR. LRRK2 kinase inhibition protects against Parkinson's disease-associated environmental toxicants. Neurobiology of Disease. 106522. PMID 38705492 DOI: 10.1016/j.nbd.2024.106522 |
0.382 |
|
| 2023 |
Van Laar AD, Webb KR, Keeney MT, Van Laar VS, Zharikov A, Burton EA, Hastings TG, Glajch KE, Hirst WD, Greenamyre JT, Rocha EM. Transient exposure to rotenone causes degeneration and progressive parkinsonian motor deficits, neuroinflammation, and synucleinopathy. Npj Parkinson's Disease. 9: 121. PMID 37567894 DOI: 10.1038/s41531-023-00561-6 |
0.605 |
|
| 2023 |
Di Maio R, Keeney MT, Cechova V, Mortimer A, Sekandari A, Rowart P, Greenamyre JT, Freeman BA, Fazzari M. Neuroprotective actions of a fatty acid nitroalkene in Parkinson's disease. Npj Parkinson's Disease. 9: 55. PMID 37029127 DOI: 10.1038/s41531-023-00502-3 |
0.375 |
|
| 2022 |
Hallacli E, Kayatekin C, Nazeen S, Wang XH, Sheinkopf Z, Sathyakumar S, Sarkar S, Jiang X, Dong X, Di Maio R, Wang W, Keeney MT, Felsky D, Sandoe J, Vahdatshoar A, ... ... Greenamyre JT, et al. The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability. Cell. 185: 2035-2056.e33. PMID 35688132 DOI: 10.1016/j.cell.2022.05.008 |
0.308 |
|
| 2022 |
Keeney MT, Hoffman EK, Farmer K, Bodle CR, Fazzari M, Zharikov A, Castro SL, Hu X, Mortimer A, Kofler JK, Cifuentes-Pagano E, Pagano PJ, Burton EA, Hastings TG, Greenamyre JT, et al. NADPH oxidase 2 activity in Parkinson's disease. Neurobiology of Disease. 105754. PMID 35577065 DOI: 10.1016/j.nbd.2022.105754 |
0.418 |
|
| 2022 |
Rocha EM, Keeney MT, Di Maio R, De Miranda BR, Greenamyre JT. LRRK2 and idiopathic Parkinson's disease. Trends in Neurosciences. PMID 34991886 DOI: 10.1016/j.tins.2021.12.002 |
0.572 |
|
| 2021 |
De Miranda BR, Goldman SM, Miller GW, Greenamyre JT, Dorsey ER. Preventing Parkinson's Disease: An Environmental Agenda. Journal of Parkinson's Disease. PMID 34719434 DOI: 10.3233/JPD-212922 |
0.308 |
|
| 2021 |
Buck SA, Steinkellner T, Aslanoglou D, Villeneuve M, Bhatte SH, Childers VC, Rubin SA, De Miranda BR, O'Leary EI, Neureiter EG, Fogle KJ, Palladino MJ, Logan RW, Glausier JR, Fish KN, ... ... Greenamyre JT, et al. Vesicular glutamate transporter modulates sex differences in dopamine neuron vulnerability to age-related neurodegeneration. Aging Cell. e13365. PMID 33909313 DOI: 10.1111/acel.13365 |
0.8 |
|
| 2021 |
Buck SA, Miranda BR, Logan RW, Fish KN, Greenamyre JT, Freyberg Z. VGLUT2 is a determinant of dopamine neuron resilience in a rotenone model of dopamine neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33893220 DOI: 10.1523/JNEUROSCI.2770-20.2021 |
0.831 |
|
| 2021 |
De Miranda BR, Castro SL, Rocha EM, Bodle CR, Johnson KE, Greenamyre JT. The industrial solvent trichloroethylene induces LRRK2 kinase activity and dopaminergic neurodegeneration in a rat model of Parkinson's disease. Neurobiology of Disease. 105312. PMID 33636387 DOI: 10.1016/j.nbd.2021.105312 |
0.651 |
|
| 2020 |
Bucher ML, Barrett CW, Moon CJ, Mortimer AD, Burton EA, Greenamyre JT, Hastings TG. Acquired dysregulation of dopamine homeostasis reproduces features of Parkinson's disease. Npj Parkinson's Disease. 6: 34. PMID 33298952 DOI: 10.1038/s41531-020-00134-x |
0.322 |
|
| 2020 |
De Miranda BR, Rocha EM, Castro SL, Greenamyre JT. Protection from α-Synuclein induced dopaminergic neurodegeneration by overexpression of the mitochondrial import receptor TOM20. Npj Parkinson's Disease. 6: 38. PMID 33293540 DOI: 10.1038/s41531-020-00139-6 |
0.644 |
|
| 2020 |
Van Laar VS, Chen J, Zharikov AD, Bai Q, Di Maio R, Dukes AA, Hastings TG, Watkins SC, Greenamyre JT, St Croix CM, Burton EA. α-Synuclein amplifies cytoplasmic peroxide flux and oxidative stress provoked by mitochondrial inhibitors in CNS dopaminergic neurons in vivo. Redox Biology. 37: 101695. PMID 32905883 DOI: 10.1016/J.Redox.2020.101695 |
0.46 |
|
| 2020 |
De Miranda BR, Greenamyre JT. Trichloroethylene, a ubiquitous environmental contaminant in the risk for Parkinson's disease. Environmental Science. Processes & Impacts. PMID 31996877 DOI: 10.1039/c9em00578a |
0.404 |
|
| 2019 |
Rocha EM, De Miranda BR, Castro S, Drolet R, Hatcher NG, Yao L, Smith SM, Keeney MT, Di Maio R, Kofler J, Hastings TG, Greenamyre JT. LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease. Neurobiology of Disease. 104626. PMID 31618685 DOI: 10.1016/J.Nbd.2019.104626 |
0.755 |
|
| 2019 |
Tapias V, McCoy JL, Greenamyre JT. Phenothiazine normalizes the NADH/NAD ratio, maintains mitochondrial integrity and protects the nigrostriatal dopamine system in a chronic rotenone model of Parkinson's disease. Redox Biology. 24: 101164. PMID 30925294 DOI: 10.1016/j.redox.2019.101164 |
0.523 |
|
| 2019 |
De Miranda BR, Fazzari M, Rocha EM, Castro S, Greenamyre JT. Sex differences in rotenone sensitivity reflect the male-to-female ratio in human Parkinson's disease incidence. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30907971 DOI: 10.1093/Toxsci/Kfz082 |
0.613 |
|
| 2019 |
Espay AJ, Vizcarra JA, Marsili L, Lang AE, Simon DK, Merola A, Josephs KA, Fasano A, Morgante F, Savica R, Greenamyre JT, Cambi F, Yamasaki TR, Tanner CM, Gan-Or Z, et al. Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases. Neurology. 92: 329-337. PMID 30745444 DOI: 10.1212/Wnl.0000000000006926 |
0.732 |
|
| 2018 |
Baskota SU, Lopez OL, Greenamyre JT, Kofler J. Spectrum of tau pathologies in Huntington's disease. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 30573872 DOI: 10.1038/S41374-018-0166-9 |
0.315 |
|
| 2018 |
Shihabuddin LS, Brundin P, Greenamyre JT, Stephenson D, Sardi SP. New Frontiers in Parkinson's Disease: From Genetics to the Clinic. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 38: 9375-9382. PMID 30381429 DOI: 10.1523/JNEUROSCI.1666-18.2018 |
0.404 |
|
| 2018 |
Greenamyre JT. What's wrong with mitochondria in Parkinson's disease? Movement Disorders : Official Journal of the Movement Disorder Society. 33: 1515-1517. PMID 30288798 DOI: 10.1002/mds.98 |
0.394 |
|
| 2018 |
Di Maio R, Hoffman EK, Rocha EM, Keeney MT, Sanders LH, De Miranda BR, Zharikov A, Van Laar A, Stepan AF, Lanz TA, Kofler JK, Burton EA, Alessi DR, Hastings TG, Greenamyre JT. LRRK2 activation in idiopathic Parkinson's disease. Science Translational Medicine. 10. PMID 30045977 DOI: 10.1126/Scitranslmed.Aar5429 |
0.793 |
|
| 2018 |
Sanders LH, Rouanet JP, Howlett EH, Leuthner TC, Rooney JP, Greenamyre JT, Meyer JN. Newly Revised Quantitative PCR-Based Assay for Mitochondrial and Nuclear DNA Damage. Current Protocols in Toxicology. 76: e50. PMID 30040241 DOI: 10.1002/Cptx.50 |
0.67 |
|
| 2018 |
Van Laar VS, Arnold B, Howlett EH, Calderon MJ, St Croix CM, Greenamyre JT, Sanders LH, Berman SB. Evidence for compartmentalized axonal mitochondrial biogenesis: Mitochondrial DNA replication increases in distal axons as an early response to Parkinson's disease-relevant stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30030401 DOI: 10.1523/Jneurosci.0541-18.2018 |
0.722 |
|
| 2017 |
Welty S, Teng Y, Liang Z, Zhao W, Sanders L, Greenamyre JT, Rubio ME, Thathiah A, Kodali R, Wetzel R, Levine AS, Lan L. RAD52 is required for RNA-templated recombination repair in post-mitotic neurons. The Journal of Biological Chemistry. PMID 29217771 DOI: 10.1074/Jbc.M117.808402 |
0.679 |
|
| 2017 |
Howlett EH, Jensen N, Belmonte F, Zafar F, Hu X, Kluss J, Schüle B, Kaufman BA, Greenamyre JT, Sanders LH. LRRK2 G2019S-induced mitochondrial DNA damage is LRRK2 kinase dependent and inhibition restores mtDNA integrity in Parkinson's disease. Human Molecular Genetics. PMID 28973664 DOI: 10.1093/Hmg/Ddx320 |
0.805 |
|
| 2017 |
Milanese C, Tapias V, Gabriels S, Cerri S, Levandis G, Blandini F, Tresini M, Shiva S, Greenamyre JT, Gladwin MT, Mastroberardino PG. Mitochondrial complex I reversible S-nitrosation improves bioenergetics and is protective in Parkinson's disease. Antioxidants & Redox Signaling. PMID 28816057 DOI: 10.1089/Ars.2017.6992 |
0.708 |
|
| 2017 |
Sanders LH, Paul KC, Howlett EH, Lawal H, Boppana S, Bronstein JM, Ritz B, Greenamyre JT. Base excision repair variants and pesticide exposure increase Parkinson's disease risk. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28460087 DOI: 10.1093/Toxsci/Kfx086 |
0.728 |
|
| 2017 |
Greenamyre JT, De Miranda BR, Bucher ML, Singleton AB, Tansey MG. The Gordon Research Seminar & Conference on Parkinson’s disease: state of the Science 200 years after James Parkinson’s essay on the Shaking Palsy Npj Parkinson's Disease. 3. DOI: 10.1038/S41531-017-0028-Y |
0.47 |
|
| 2016 |
Di Maio R, Barrett PJ, Hoffman EK, Barrett CW, Zharikov A, Borah A, Hu X, McCoy J, Chu CT, Burton EA, Hastings TG, Greenamyre JT. α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson's disease. Science Translational Medicine. 8: 342ra78. PMID 27280685 DOI: 10.1126/Scitranslmed.Aaf3634 |
0.663 |
|
| 2016 |
Sahoo B, Arduini I, Drombosky KW, Kodali R, Sanders LH, Greenamyre JT, Wetzel R. Folding Landscape of Mutant Huntingtin Exon1: Diffusible Multimers, Oligomers and Fibrils, and No Detectable Monomer. Plos One. 11: e0155747. PMID 27271685 DOI: 10.1371/Journal.Pone.0155747 |
0.67 |
|
| 2015 |
Greenamyre JT, Sanders LH, Gasser T. Fruit flies, bile acids, and Parkinson disease: A mitochondrial connection? Neurology. 85: 838-9. PMID 26253445 DOI: 10.1212/Wnl.0000000000001912 |
0.754 |
|
| 2015 |
Zharikov AD, Cannon JR, Tapias V, Bai Q, Horowitz MP, Shah V, El Ayadi A, Hastings TG, Greenamyre JT, Burton EA. shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson's disease model. The Journal of Clinical Investigation. PMID 26075822 DOI: 10.1172/Jci64502 |
0.805 |
|
| 2015 |
Tyurina YY, Polimova AM, Maciel E, Tyurin VA, Kapralova VI, Winnica DE, Vikulina AS, Domingues MR, McCoy J, Sanders LH, Bay?r H, Greenamyre JT, Kagan VE. LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: Implication for mitochondrial dysfunction in Parkinson's disease. Free Radical Research. 49: 681-91. PMID 25740198 DOI: 10.3109/10715762.2015.1005085 |
0.72 |
|
| 2015 |
Rooney JP, Ryde IT, Sanders LH, Howlett EH, Colton MD, Germ KE, Mayer GD, Greenamyre JT, Meyer JN. PCR based determination of mitochondrial DNA copy number in multiple species. Methods in Molecular Biology (Clifton, N.J.). 1241: 23-38. PMID 25308485 DOI: 10.1007/978-1-4939-1875-1_3 |
0.664 |
|
| 2015 |
Lee JW, Tapias V, Di Maio R, Greenamyre JT, Cannon JR. Behavioral, neurochemical, and pathologic alterations in bacterial artificial chromosome transgenic G2019S leucine-rich repeated kinase 2 rats. Neurobiology of Aging. 36: 505-18. PMID 25174649 DOI: 10.1016/J.Neurobiolaging.2014.07.011 |
0.696 |
|
| 2015 |
Greenamyre JT, Barrett P. Genetic Factors in Environmentally Induced Disease Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders. 21-43. DOI: 10.1016/B978-0-12-800228-5.00002-9 |
0.504 |
|
| 2014 |
Sanders LH, Howlett EH, McCoy J, Greenamyre JT. Mitochondrial DNA damage as a peripheral biomarker for mitochondrial toxin exposure in rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 142: 395-402. PMID 25237061 DOI: 10.1093/Toxsci/Kfu185 |
0.692 |
|
| 2014 |
Sanders LH, McCoy J, Hu X, Mastroberardino PG, Dickinson BC, Chang CJ, Chu CT, Van Houten B, Greenamyre JT. Mitochondrial DNA damage: molecular marker of vulnerable nigral neurons in Parkinson's disease. Neurobiology of Disease. 70: 214-23. PMID 24981012 DOI: 10.1016/J.Nbd.2014.06.014 |
0.822 |
|
| 2014 |
Schapira AH, Olanow CW, Greenamyre JT, Bezard E. Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: future therapeutic perspectives. Lancet (London, England). 384: 545-55. PMID 24954676 DOI: 10.1016/S0140-6736(14)61010-2 |
0.421 |
|
| 2014 |
Tapias V, Greenamyre JT. A rapid and sensitive automated image-based approach for in vitro and in vivo characterization of cell morphology and quantification of cell number and neurite architecture. Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. 68: 12.33.1-12.33.22. PMID 24692056 DOI: 10.1002/0471142956.cy1233s68 |
0.327 |
|
| 2014 |
Tapias V, Cannon JR, Greenamyre JT. Pomegranate juice exacerbates oxidative stress and nigrostriatal degeneration in Parkinson's disease. Neurobiology of Aging. 35: 1162-76. PMID 24315037 DOI: 10.1016/J.Neurobiolaging.2013.10.077 |
0.685 |
|
| 2014 |
Sanders LH, Laganière J, Cooper O, Mak SK, Vu BJ, Huang YA, Paschon DE, Vangipuram M, Sundararajan R, Urnov FD, Langston JW, Gregory PD, Zhang HS, Greenamyre JT, Isacson O, et al. LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction. Neurobiology of Disease. 62: 381-6. PMID 24148854 DOI: 10.1016/J.Nbd.2013.10.013 |
0.692 |
|
| 2013 |
Sanders LH, Greenamyre JT. Oxidative damage to macromolecules in human Parkinson disease and the rotenone model. Free Radical Biology & Medicine. 62: 111-20. PMID 23328732 DOI: 10.1016/J.Freeradbiomed.2013.01.003 |
0.744 |
|
| 2013 |
Tapias V, Greenamyre JT, Watkins SC. Automated imaging system for fast quantitation of neurons, cell morphology and neurite morphometry in vivo and in vitro. Neurobiology of Disease. 54: 158-68. PMID 23220621 DOI: 10.1016/J.Nbd.2012.11.018 |
0.336 |
|
| 2013 |
Cannon JR, Geghman KD, Tapias V, Sew T, Dail MK, Li C, Greenamyre JT. Expression of human E46K-mutated α-synuclein in BAC-transgenic rats replicates early-stage Parkinson's disease features and enhances vulnerability to mitochondrial impairment. Experimental Neurology. 240: 44-56. PMID 23153578 DOI: 10.1016/J.Expneurol.2012.11.007 |
0.674 |
|
| 2013 |
Mullett SJ, Di Maio R, Greenamyre JT, Hinkle DA. DJ-1 expression modulates astrocyte-mediated protection against neuronal oxidative stress. Journal of Molecular Neuroscience : Mn. 49: 507-11. PMID 23065353 DOI: 10.1007/S12031-012-9904-4 |
0.454 |
|
| 2013 |
Di Maio R, Mastroberardino PG, Hu X, Montero LM, Greenamyre JT. Thiol oxidation and altered NR2B/NMDA receptor functions in in vitro and in vivo pilocarpine models: implications for epileptogenesis. Neurobiology of Disease. 49: 87-98. PMID 22824136 DOI: 10.1016/J.Nbd.2012.07.013 |
0.691 |
|
| 2013 |
Cannon JR, Greenamyre JT. Gene-environment interactions in Parkinson's disease: specific evidence in humans and mammalian models. Neurobiology of Disease. 57: 38-46. PMID 22776331 DOI: 10.1016/J.Nbd.2012.06.025 |
0.615 |
|
| 2013 |
Greenamyre JT, Cannon JR, Sanders LH, Tapias V, Bai Q, Volpicelli-Daley L, Lee VM, Burton EA. Synuclein-Mitochondrial Interactions in Substantia Nigra Dopamine Neurons Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 126-127. DOI: 10.1016/B978-0-12-800044-1.00111-2 |
0.763 |
|
| 2012 |
Muñoz P, Paris I, Sanders LH, Greenamyre JT, Segura-Aguilar J. Overexpression of VMAT-2 and DT-diaphorase protects substantia nigra-derived cells against aminochrome neurotoxicity. Biochimica Et Biophysica Acta. 1822: 1125-36. PMID 22483869 DOI: 10.1016/J.Bbadis.2012.03.010 |
0.683 |
|
| 2012 |
Milanese C, Sager JJ, Bai Q, Farrell TC, Cannon JR, Greenamyre JT, Burton EA. Hypokinesia and reduced dopamine levels in zebrafish lacking β- and γ1-synucleins. The Journal of Biological Chemistry. 287: 2971-83. PMID 22128150 DOI: 10.1074/Jbc.M111.308312 |
0.634 |
|
| 2012 |
Martinez TN, Greenamyre JT. Toxin models of mitochondrial dysfunction in Parkinson's disease. Antioxidants & Redox Signaling. 16: 920-34. PMID 21554057 DOI: 10.1089/ars.2011.4033 |
0.808 |
|
| 2011 |
Sanders LH, Greenamyre JT. Regulation of complex I by Engrailed is complex too. Nature Neuroscience. 14: 1221-2. PMID 21952262 DOI: 10.1038/Nn.2939 |
0.702 |
|
| 2011 |
Cannon JR, Greenamyre JT. The role of environmental exposures in neurodegeneration and neurodegenerative diseases. Toxicological Sciences : An Official Journal of the Society of Toxicology. 124: 225-50. PMID 21914720 DOI: 10.1093/Toxsci/Kfr239 |
0.606 |
|
| 2011 |
Jain S, Siegle GJ, Gu C, Moore CG, Ivanco LS, Studenski S, Greenamyre JT, Steinhauer SR. Pupillary unrest correlates with arousal symptoms and motor signs in Parkinson disease. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 1344-7. PMID 21506163 DOI: 10.1002/Mds.23628 |
0.347 |
|
| 2011 |
D'Aiuto L, Di Maio R, Mohan KN, Minervini C, Saporiti F, Soreca I, Greenamyre JT, Chaillet JR. Mouse ES cells overexpressing DNMT1 produce abnormal neurons with upregulated NMDA/NR1 subunit. Differentiation; Research in Biological Diversity. 82: 9-17. PMID 21492995 DOI: 10.1016/J.Diff.2011.03.003 |
0.734 |
|
| 2011 |
Paris I, Muñoz P, Huenchuguala S, Couve E, Sanders LH, Greenamyre JT, Caviedes P, Segura-Aguilar J. Autophagy protects against aminochrome-induced cell death in substantia nigra-derived cell line. Toxicological Sciences : An Official Journal of the Society of Toxicology. 121: 376-88. PMID 21427056 DOI: 10.1093/Toxsci/Kfr060 |
0.663 |
|
| 2011 |
Di Maio R, Mastroberardino PG, Hu X, Montero L, Greenamyre JT. Pilocapine alters NMDA receptor expression and function in hippocampal neurons: NADPH oxidase and ERK1/2 mechanisms. Neurobiology of Disease. 42: 482-95. PMID 21397025 DOI: 10.1016/J.Nbd.2011.02.012 |
0.692 |
|
| 2011 |
Horowitz MP, Milanese C, Di Maio R, Hu X, Montero LM, Sanders LH, Tapias V, Sepe S, van Cappellen WA, Burton EA, Greenamyre JT, Mastroberardino PG. Single-cell redox imaging demonstrates a distinctive response of dopaminergic neurons to oxidative insults. Antioxidants & Redox Signaling. 15: 855-71. PMID 21395478 DOI: 10.1089/Ars.2010.3629 |
0.805 |
|
| 2011 |
Hu X, Weng Z, Chu CT, Zhang L, Cao G, Gao Y, Signore A, Zhu J, Hastings T, Greenamyre JT, Chen J. Peroxiredoxin-2 protects against 6-hydroxydopamine-induced dopaminergic neurodegeneration via attenuation of the apoptosis signal-regulating kinase (ASK1) signaling cascade. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 247-61. PMID 21209210 DOI: 10.1523/JNEUROSCI.4589-10.2011 |
0.352 |
|
| 2011 |
Jain S, Siegle GJ, Gu C, Moore CG, Ivanco LS, Jennings JR, Steinhauer SR, Studenski S, Greenamyre JT. Autonomic insufficiency in pupillary and cardiovascular systems in Parkinson's disease. Parkinsonism & Related Disorders. 17: 119-22. PMID 21115264 DOI: 10.1016/J.Parkreldis.2010.11.005 |
0.386 |
|
| 2011 |
Cannon JR, Sew T, Montero L, Burton EA, Greenamyre JT. Pseudotype-dependent lentiviral transduction of astrocytes or neurons in the rat substantia nigra. Experimental Neurology. 228: 41-52. PMID 21056560 DOI: 10.1016/J.Expneurol.2010.10.016 |
0.575 |
|
| 2010 |
Cannon JR, Greenamyre JT. Neurotoxic in vivo models of Parkinson's disease recent advances. Progress in Brain Research. 184: 17-33. PMID 20887868 DOI: 10.1016/S0079-6123(10)84002-6 |
0.625 |
|
| 2010 |
Horowitz MP, Greenamyre JT. Gene-environment interactions in Parkinson's disease: the importance of animal modeling. Clinical Pharmacology and Therapeutics. 88: 467-74. PMID 20811350 DOI: 10.1038/clpt.2010.138 |
0.72 |
|
| 2010 |
Horowitz MP, Greenamyre JT. Mitochondrial iron metabolism and its role in neurodegeneration. Journal of Alzheimer's Disease : Jad. 20: S551-68. PMID 20463401 DOI: 10.3233/JAD-2010-100354 |
0.691 |
|
| 2010 |
Greene JG, Dingledine R, Greenamyre JT. Neuron-selective changes in RNA transcripts related to energy metabolism in toxic models of parkinsonism in rodents. Neurobiology of Disease. 38: 476-81. PMID 20307667 DOI: 10.1016/j.nbd.2010.03.014 |
0.762 |
|
| 2010 |
Greenamyre JT, Cannon JR, Drolet R, Mastroberardino PG. Lessons from the rotenone model of Parkinson's disease. Trends in Pharmacological Sciences. 31: 141-2; author reply . PMID 20096940 DOI: 10.1016/J.Tips.2009.12.006 |
0.838 |
|
| 2010 |
Tapias V, Cannon JR, Greenamyre JT. Melatonin treatment potentiates neurodegeneration in a rat rotenone Parkinson's disease model. Journal of Neuroscience Research. 88: 420-7. PMID 19681169 DOI: 10.1002/Jnr.22201 |
0.671 |
|
| 2009 |
Cannon JR, Greenamyre JT. NeuN is not a reliable marker of dopamine neurons in rat substantia nigra. Neuroscience Letters. 464: 14-7. PMID 19682546 DOI: 10.1016/J.Neulet.2009.08.023 |
0.608 |
|
| 2009 |
Drolet RE, Cannon JR, Montero L, Greenamyre JT. Chronic rotenone exposure reproduces Parkinson's disease gastrointestinal neuropathology. Neurobiology of Disease. 36: 96-102. PMID 19595768 DOI: 10.1016/J.Nbd.2009.06.017 |
0.761 |
|
| 2009 |
Cannon JR, Tapias V, Na HM, Honick AS, Drolet RE, Greenamyre JT. A highly reproducible rotenone model of Parkinson's disease. Neurobiology of Disease. 34: 279-90. PMID 19385059 DOI: 10.1016/J.Nbd.2009.01.016 |
0.775 |
|
| 2009 |
Bayir H, Kapralov AA, Jiang J, Huang Z, Tyurina YY, Tyurin VA, Zhao Q, Belikova NA, Vlasova II, Maeda A, Zhu J, Na HM, Mastroberardino PG, Sparvero LJ, Amoscato AA, ... ... Greenamyre JT, et al. Peroxidase mechanism of lipid-dependent cross-linking of synuclein with cytochrome C: protection against apoptosis versus delayed oxidative stress in Parkinson disease. The Journal of Biological Chemistry. 284: 15951-69. PMID 19351880 DOI: 10.1074/Jbc.M900418200 |
0.686 |
|
| 2009 |
Mastroberardino PG, Hoffman EK, Horowitz MP, Betarbet R, Taylor G, Cheng D, Na HM, Gutekunst CA, Gearing M, Trojanowski JQ, Anderson M, Chu CT, Peng J, Greenamyre JT. A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease. Neurobiology of Disease. 34: 417-31. PMID 19250966 DOI: 10.1016/J.Nbd.2009.02.009 |
0.823 |
|
| 2009 |
Drolet RE, Cannon JR, Montero LM, Greenamyre JT. T1782 Rotenone Recapitulates Parkinson's Disease-Related Gastrointestinal Motility Deficits and Alpha-Synuclein Pathology in the Enteric Nervous System Gastroenterology. 136: A-578-A-579. DOI: 10.1016/S0016-5085(09)62663-9 |
0.722 |
|
| 2008 |
Mastroberardino PG, Orr AL, Hu X, Na HM, Greenamyre JT. A FRET-based method to study protein thiol oxidation in histological preparations. Free Radical Biology & Medicine. 45: 971-81. PMID 18620047 DOI: 10.1016/J.Freeradbiomed.2008.06.018 |
0.67 |
|
| 2008 |
Orr AL, Li S, Wang CE, Li H, Wang J, Rong J, Xu X, Mastroberardino PG, Greenamyre JT, Li XJ. N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 2783-92. PMID 18337408 DOI: 10.1523/Jneurosci.0106-08.2008 |
0.682 |
|
| 2008 |
Marella M, Seo BB, Nakamaru-Ogiso E, Greenamyre JT, Matsuno-Yagi A, Yagi T. Protection by the NDI1 gene against neurodegeneration in a rotenone rat model of Parkinson's disease. Plos One. 3: e1433. PMID 18197244 DOI: 10.1371/journal.pone.0001433 |
0.51 |
|
| 2008 |
Greene JG, Greenamyre JT, Dingledine R. Sequential and concerted gene expression changes in a chronic in vitro model of parkinsonism. Neuroscience. 152: 198-207. PMID 18191903 DOI: 10.1016/j.neuroscience.2007.11.029 |
0.737 |
|
| 2008 |
Betarbet R, Greenamyre JT. Complex I Inhibition, Rotenone and Parkinson's Disease Parkinson's Disease. 195-206. DOI: 10.1016/B978-0-12-374028-1.00014-2 |
0.707 |
|
| 2007 |
Betarbet R, Greenamyre JT. Parkinson's disease: animal models. Handbook of Clinical Neurology. 83: 265-87. PMID 18808918 DOI: 10.1016/S0072-9752(07)83011-9 |
0.752 |
|
| 2007 |
Greenamyre JT. Huntington's disease: getting closer. The American Journal of Psychiatry. 164: 1318. PMID 17728414 DOI: 10.1176/appi.ajp.2007.07071201 |
0.321 |
|
| 2007 |
Greenamyre JT. Huntington's disease--making connections. The New England Journal of Medicine. 356: 518-20. PMID 17267914 DOI: 10.1056/NEJMcibr067022 |
0.323 |
|
| 2007 |
Sherer TB, Richardson JR, Testa CM, Seo BB, Panov AV, Yagi T, Matsuno-Yagi A, Miller GW, Greenamyre JT. Mechanism of toxicity of pesticides acting at complex I: relevance to environmental etiologies of Parkinson's disease. Journal of Neurochemistry. 100: 1469-79. PMID 17241123 DOI: 10.1111/J.1471-4159.2006.04333.X |
0.832 |
|
| 2007 |
Richardson JR, Caudle WM, Guillot TS, Watson JL, Nakamaru-Ogiso E, Seo BB, Sherer TB, Greenamyre JT, Yagi T, Matsuno-Yagi A, Miller GW. Obligatory role for complex I inhibition in the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Toxicological Sciences : An Official Journal of the Society of Toxicology. 95: 196-204. PMID 17038483 DOI: 10.1093/Toxsci/Kfl133 |
0.73 |
|
| 2006 |
Berman SB, Greenamyre JT. Update on Huntington's disease. Current Neurology and Neuroscience Reports. 6: 281-6. PMID 16822347 DOI: 10.1007/s11910-006-0019-6 |
0.362 |
|
| 2006 |
Pallanck L, Greenamyre JT. Neurodegenerative disease: pink, parkin and the brain. Nature. 441: 1058. PMID 16810237 DOI: 10.1038/4411058a |
0.39 |
|
| 2006 |
Chen Y, Yu M, Jones DP, Greenamyre JT, Cai J. Protection against oxidant-induced apoptosis by mitochondrial thioredoxin in SH-SY5Y neuroblastoma cells. Toxicology and Applied Pharmacology. 216: 256-62. PMID 16797630 DOI: 10.1016/j.taap.2006.05.006 |
0.358 |
|
| 2006 |
Betarbet R, Canet-Aviles RM, Sherer TB, Mastroberardino PG, McLendon C, Kim JH, Lund S, Na HM, Taylor G, Bence NF, Kopito R, Seo BB, Yagi T, Yagi A, Klinefelter G, ... ... Greenamyre JT, et al. Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system. Neurobiology of Disease. 22: 404-20. PMID 16439141 DOI: 10.1016/J.Nbd.2005.12.003 |
0.827 |
|
| 2005 |
Panov A, Dikalov S, Shalbuyeva N, Taylor G, Sherer T, Greenamyre JT. Rotenone model of Parkinson disease: multiple brain mitochondria dysfunctions after short term systemic rotenone intoxication. The Journal of Biological Chemistry. 280: 42026-35. PMID 16243845 DOI: 10.1074/Jbc.M508628200 |
0.67 |
|
| 2005 |
Richardson JR, Quan Y, Sherer TB, Greenamyre JT, Miller GW. Paraquat neurotoxicity is distinct from that of MPTP and rotenone. Toxicological Sciences : An Official Journal of the Society of Toxicology. 88: 193-201. PMID 16141438 DOI: 10.1093/Toxsci/Kfi304 |
0.714 |
|
| 2005 |
Sherer TB, Greenamyre JT. Oxidative damage in Parkinson's disease. Antioxidants & Redox Signaling. 7: 627-9. PMID 15890006 DOI: 10.1089/ars.2005.7.627 |
0.674 |
|
| 2005 |
Testa CM, Sherer TB, Greenamyre JT. Rotenone induces oxidative stress and dopaminergic neuron damage in organotypic substantia nigra cultures. Brain Research. Molecular Brain Research. 134: 109-18. PMID 15790535 DOI: 10.1016/J.Molbrainres.2004.11.007 |
0.825 |
|
| 2005 |
Panov AV, Lund S, Greenamyre JT. Ca2+-induced permeability transition in human lymphoblastoid cell mitochondria from normal and Huntington's disease individuals. Molecular and Cellular Biochemistry. 269: 143-52. PMID 15786727 DOI: 10.1007/s11010-005-3454-9 |
0.355 |
|
| 2005 |
Greene JG, Dingledine R, Greenamyre JT. Gene expression profiling of rat midbrain dopamine neurons: implications for selective vulnerability in parkinsonism. Neurobiology of Disease. 18: 19-31. PMID 15649693 DOI: 10.1016/j.nbd.2004.10.003 |
0.766 |
|
| 2005 |
Betarbet R, Sherer TB, Greenamyre JT. Ubiquitin-proteasome system and Parkinson's diseases. Experimental Neurology. 191: S17-27. PMID 15629758 DOI: 10.1016/J.Expneurol.2004.08.021 |
0.821 |
|
| 2005 |
Greene JG, Greenamyre JT. Mitochondria, metabolic inhibitors and neurodegeneration Neurodegenerative Diseases: Neurobiology, Pathogenesis and Therapeutics. 33-43. DOI: 10.1017/CBO9780511544873.004 |
0.566 |
|
| 2005 |
Sherer TB, Betarbet R, Greenamyre JT. Rotenone rat and other neurotoxin models of parkinson disease Movement Disorders. 161-172. DOI: 10.1016/B978-012088382-0/50013-X |
0.782 |
|
| 2004 |
Caboni P, Sherer TB, Zhang N, Taylor G, Na HM, Greenamyre JT, Casida JE. Rotenone, deguelin, their metabolites, and the rat model of Parkinson's disease. Chemical Research in Toxicology. 17: 1540-8. PMID 15540952 DOI: 10.1021/Tx049867R |
0.695 |
|
| 2004 |
Papa SM, Auberson YP, Greenamyre JT. Prolongation of levodopa responses by glycineB antagonists in parkinsonian primates. Annals of Neurology. 56: 723-7. PMID 15470750 DOI: 10.1002/ana.20279 |
0.311 |
|
| 2004 |
Betarbet R, Greenamyre JT. Regulation of dopamine receptor and neuropeptide expression in the basal ganglia of monkeys treated with MPTP. Experimental Neurology. 189: 393-403. PMID 15380489 DOI: 10.1016/J.Expneurol.2004.05.041 |
0.711 |
|
| 2004 |
Soares J, Kliem MA, Betarbet R, Greenamyre JT, Yamamoto B, Wichmann T. Role of external pallidal segment in primate parkinsonism: comparison of the effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism and lesions of the external pallidal segment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6417-26. PMID 15269251 DOI: 10.1523/Jneurosci.0836-04.2004 |
0.726 |
|
| 2004 |
Greenamyre JT, Hastings TG. Biomedicine. Parkinson's--divergent causes, convergent mechanisms. Science (New York, N.Y.). 304: 1120-2. PMID 15155938 DOI: 10.1126/science.1098966 |
0.464 |
|
| 2004 |
Betarbet R, Poisik O, Sherer TB, Greenamyre JT. Differential expression and ser897 phosphorylation of striatal N-methyl-d-aspartate receptor subunit NR1 in animal models of Parkinson's disease. Experimental Neurology. 187: 76-85. PMID 15081590 DOI: 10.1016/J.Expneurol.2003.12.012 |
0.811 |
|
| 2003 |
Sherer TB, Betarbet R, Testa CM, Seo BB, Richardson JR, Kim JH, Miller GW, Yagi T, Matsuno-Yagi A, Greenamyre JT. Mechanism of toxicity in rotenone models of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10756-64. PMID 14645467 DOI: 10.1523/Jneurosci.23-34-10756.2003 |
0.826 |
|
| 2003 |
Greenamyre JT, Betarbet R, Sherer TB. The rotenone model of Parkinson's disease: genes, environment and mitochondria. Parkinsonism & Related Disorders. 9: S59-64. PMID 12915069 DOI: 10.1016/S1353-8020(03)00023-3 |
0.811 |
|
| 2003 |
Sherer TB, Betarbet R, Kim JH, Greenamyre JT. Selective microglial activation in the rat rotenone model of Parkinson's disease. Neuroscience Letters. 341: 87-90. PMID 12686372 DOI: 10.1016/S0304-3940(03)00172-1 |
0.819 |
|
| 2003 |
Panov AV, Burke JR, Strittmatter WJ, Greenamyre JT. In vitro effects of polyglutamine tracts on Ca2+-dependent depolarization of rat and human mitochondria: relevance to Huntington's disease. Archives of Biochemistry and Biophysics. 410: 1-6. PMID 12559971 DOI: 10.1016/S0003-9861(02)00585-4 |
0.395 |
|
| 2003 |
Sherer TB, Kim JH, Betarbet R, Greenamyre JT. Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation. Experimental Neurology. 179: 9-16. PMID 12504863 DOI: 10.1006/Exnr.2002.8072 |
0.825 |
|
| 2002 |
Stephans SE, Miller GW, Levey AI, Greenamyre JT. Acute mitochondrial and chronic toxicological effects of 1-methyl-4-phenylpyridinium in human neuroblastoma cells. Neurotoxicology. 23: 569-80. PMID 12428729 DOI: 10.1016/S0161-813X(02)00060-8 |
0.806 |
|
| 2002 |
Betarbet R, Sherer TB, Di Monte DA, Greenamyre JT. Mechanistic approaches to Parkinson's disease pathogenesis. Brain Pathology (Zurich, Switzerland). 12: 499-510. PMID 12408237 DOI: 10.1111/J.1750-3639.2002.Tb00468.X |
0.826 |
|
| 2002 |
Sherer TB, Betarbet R, Stout AK, Lund S, Baptista M, Panov AV, Cookson MR, Greenamyre JT. An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7006-15. PMID 12177198 |
0.805 |
|
| 2002 |
Panov AV, Gutekunst CA, Leavitt BR, Hayden MR, Burke JR, Strittmatter WJ, Greenamyre JT. Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines. Nature Neuroscience. 5: 731-6. PMID 12089530 DOI: 10.1038/Nn884 |
0.361 |
|
| 2002 |
Sherer TB, Betarbet R, Greenamyre JT. Environment, mitochondria, and Parkinson's disease. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 8: 192-7. PMID 12061498 DOI: 10.1177/1073858402008003004 |
0.833 |
|
| 2002 |
Betarbet R, Sherer TB, Greenamyre JT. Animal models of Parkinson's disease. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 24: 308-18. PMID 11948617 DOI: 10.1002/Bies.10067 |
0.817 |
|
| 2002 |
Greenamyre JT, Shoulson I. We need something better, and we need it now: fetal striatal transplantation in Huntington's disease? Neurology. 58: 675-6. PMID 11889226 DOI: 10.1212/Wnl.58.5.675 |
0.331 |
|
| 2002 |
Sherer TB, Betarbet R, Stout AK, Lund S, Baptista M, Panov AV, Cookson MR, Greenamyre JT. An In Vitro Model of Parkinson's Disease: Linking Mitochondrial Impairment to Altered α-Synuclein Metabolism and Oxidative Damage The Journal of Neuroscience. 22: 7006-7015. DOI: 10.1523/Jneurosci.22-16-07006.2002 |
0.813 |
|
| 2001 |
Sherer TB, Betarbet R, Greenamyre JT. Pesticides and Parkinson's disease. Thescientificworldjournal. 1: 207-8. PMID 12805673 DOI: 10.1100/Tsw.2001.35 |
0.817 |
|
| 2001 |
Greenamyre JT, Sherer TB, Betarbet R, Panov AV. Complex I and Parkinson's disease. Iubmb Life. 52: 135-41. PMID 11798025 DOI: 10.1080/15216540152845939 |
0.82 |
|
| 2001 |
Sherer TB, Betarbet R, Greenamyre JT. Pathogenesis of Parkinson's disease. Current Opinion in Investigational Drugs (London, England : 2000). 2: 657-62. PMID 11569943 |
0.812 |
|
| 2001 |
Blandini F, Nappi G, Greenamyre JT. Subthalamic infusion of an NMDA antagonist prevents basal ganglia metabolic changes and nigral degeneration in a rodent model of Parkinson's disease. Annals of Neurology. 49: 525-9. PMID 11310632 DOI: 10.1002/Ana.104 |
0.421 |
|
| 2001 |
Greenamyre JT. Glutamatergic influences on the basal ganglia. Clinical Neuropharmacology. 24: 65-70. PMID 11307040 DOI: 10.1097/00002826-200103000-00001 |
0.426 |
|
| 2001 |
Shoulson I, Penney J, McDermott M, Schwid S, Kayson E, Chase T, Fahn S, Greenamyre JT, Lang A, Siderowf A, Pearson N, Harrison M, Rost E, Colcher A, Lloyd M, et al. A randomized, controlled trial of remacemide for motor fluctuations in Parkinson's disease. Neurology. 56: 455-62. PMID 11222787 |
0.528 |
|
| 2001 |
Greenamyre JT, Betarbet R, Sherer T, Panov A. Response: Parkinson's disease, pesticides and mitochondrial dysfunction Trends in Neurosciences. 24: 247. DOI: 10.1016/S0166-2236(00)01788-4 |
0.828 |
|
| 2000 |
Sherer T, Greenamyre JT. A therapeutic target and biomarker in Friedreich's ataxia. Neurology. 55: 1600-1. PMID 11113210 |
0.56 |
|
| 2000 |
Betarbet R, Sherer TB, MacKenzie G, Garcia-Osuna M, Panov AV, Greenamyre JT. Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nature Neuroscience. 3: 1301-6. PMID 11100151 DOI: 10.1038/81834 |
0.837 |
|
| 2000 |
Talpade DJ, Greene JG, Higgins DS, Greenamyre JT. In vivo labeling of mitochondrial complex I (NADH:ubiquinone oxidoreductase) in rat brain using [(3)H]dihydrorotenone. Journal of Neurochemistry. 75: 2611-21. PMID 11080215 DOI: 10.1046/J.1471-4159.2000.0752611.X |
0.781 |
|
| 2000 |
Pettus EH, Betarbet R, Cottrell B, Wallace DC, Madyastha V, Greenamyre JT. Immunocytochemical characterization of the mitochondrially encoded ND1 subunit of complex I (NADH : ubiquinone oxidoreductase) in rat brain. Journal of Neurochemistry. 75: 383-92. PMID 10854284 DOI: 10.1046/j.1471-4159.2000.0750383.x |
0.81 |
|
| 2000 |
Jha N, Jurma O, Lalli G, Liu Y, Pettus EH, Greenamyre JT, Liu RM, Forman HJ, Andersen JK. Glutathione depletion in PC12 results in selective inhibition of mitochondrial complex I activity. Implications for Parkinson's disease. The Journal of Biological Chemistry. 275: 26096-101. PMID 10846169 DOI: 10.1074/Jbc.M000120200 |
0.839 |
|
| 2000 |
Steece-Collier K, Chambers LK, Jaw-Tsai SS, Menniti FS, Greenamyre JT. Antiparkinsonian actions of CP-101,606, an antagonist of NR2B subunit-containing N-methyl-d-aspartate receptors. Experimental Neurology. 163: 239-43. PMID 10785463 DOI: 10.1006/exnr.2000.7374 |
0.366 |
|
| 2000 |
Betarbet R, Porter RH, Greenamyre JT. GluR1 glutamate receptor subunit is regulated differentially in the primate basal ganglia following nigrostriatal dopamine denervation. Journal of Neurochemistry. 74: 1166-74. PMID 10693949 DOI: 10.1046/J.1471-4159.2000.741166.X |
0.773 |
|
| 1999 |
Blandini F, Greenamyre JT. Protective and symptomatic strategies for therapy of Parkinson's disease. Drugs of Today (Barcelona, Spain : 1998). 35: 473-83. PMID 12973393 |
0.373 |
|
| 1999 |
Greenamyre JT, MacKenzie G, Peng TI, Stephans SE. Mitochondrial dysfunction in Parkinson's disease. Biochemical Society Symposium. 66: 85-97. PMID 10989660 DOI: 10.1042/Bss0660085 |
0.836 |
|
| 1999 |
Panov A, Obertone T, Bennett-Desmelik J, Greenamyre JT. Ca(2+)-dependent permeability transition and complex I activity in lymphoblast mitochondria from normal individuals and patients with Huntington's or Alzheimer's disease. Annals of the New York Academy of Sciences. 893: 365-8. PMID 10672268 DOI: 10.1111/J.1749-6632.1999.Tb07856.X |
0.315 |
|
| 1999 |
Betarbet R, Greenamyre JT. Differential expression of glutamate receptors by the dopaminergic neurons of the primate striatum. Experimental Neurology. 159: 401-8. PMID 10506511 DOI: 10.1006/Exnr.1999.7154 |
0.688 |
|
| 1999 |
Sawa A, Wiegand GW, Cooper J, Margolis RL, Sharp AH, Lawler JF, Greenamyre JT, Snyder SH, Ross CA. Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization. Nature Medicine. 5: 1194-8. PMID 10502825 DOI: 10.1038/13518 |
0.49 |
|
| 1998 |
Peng TI, Greenamyre JT. Privileged access to mitochondria of calcium influx through N-methyl-D-aspartate receptors. Molecular Pharmacology. 53: 974-80. PMID 9614198 |
0.499 |
|
| 1998 |
Greene JG, Sheu SS, Gross RA, Greenamyre JT. 3-Nitropropionic acid exacerbates N-methyl-D-aspartate toxicity in striatal culture by multiple mechanisms. Neuroscience. 84: 503-10. PMID 9539220 DOI: 10.1016/S0306-4522(97)00389-8 |
0.616 |
|
| 1998 |
Blandini F, Greenamyre JT. Prospects of glutamate antagonists in the therapy of Parkinson's disease. Fundamental & Clinical Pharmacology. 12: 4-12. PMID 9523179 |
0.398 |
|
| 1998 |
Peng TI, Jou MJ, Sheu SS, Greenamyre JT. Visualization of NMDA receptor-induced mitochondrial calcium accumulation in striatal neurons. Experimental Neurology. 149: 1-12. PMID 9454610 DOI: 10.1006/exnr.1997.6599 |
0.494 |
|
| 1998 |
Blandini F, Nappi G, Greenamyre JT. Quantitative study of mitochondrial complex I in platelets of parkinsonian patients. Movement Disorders : Official Journal of the Movement Disorder Society. 13: 11-5. PMID 9452319 DOI: 10.1002/mds.870130106 |
0.426 |
|
| 1997 |
Betarbet R, Turner R, Chockkan V, DeLong MR, Allers KA, Walters J, Levey AI, Greenamyre JT. Dopaminergic neurons intrinsic to the primate striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 6761-8. PMID 9254687 DOI: 10.1523/Jneurosci.17-17-06761.1997 |
0.699 |
|
| 1997 |
Blandini F, Garcia-Osuna M, Greenamyre JT. Subthalamic ablation reverses changes in basal ganglia oxidative metabolism and motor response to apomorphine induced by nigrostriatal lesion in rats. The European Journal of Neuroscience. 9: 1407-13. PMID 9240398 DOI: 10.1111/j.1460-9568.1997.tb01495.x |
0.376 |
|
| 1997 |
Kilbourn MR, Charalambous A, Frey KA, Sherman P, Higgins DS, Greenamyre JT. Intrastriatal neurotoxin injections reduce in vitro and in vivo binding of radiolabeled rotenoids to mitochondrial complex I. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 17: 265-72. PMID 9119899 DOI: 10.1097/00004647-199703000-00003 |
0.682 |
|
| 1997 |
Cory-Slechta DA, Garcia-Osuna M, Greenamyre JT. Lead-induced changes in NMDA receptor complex binding: correlations with learning accuracy and with sensitivity to learning impairments caused by MK-801 and NMDA administration. Behavioural Brain Research. 85: 161-74. PMID 9105573 DOI: 10.1016/S0166-4328(96)00174-X |
0.327 |
|
| 1996 |
Greene JG, Greenamyre JT. Bioenergetics and glutamate excitotoxicity. Progress in Neurobiology. 48: 613-34. PMID 8809910 DOI: 10.1016/0301-0082(96)00006-8 |
0.635 |
|
| 1996 |
Blandini F, Porter RH, Greenamyre JT. Glutamate and Parkinson's disease. Molecular Neurobiology. 12: 73-94. PMID 8732541 DOI: 10.1007/Bf02740748 |
0.664 |
|
| 1996 |
Higgins DS, Greenamyre JT. [3H]dihydrorotenone binding to NADH: ubiquinone reductase (complex I) of the electron transport chain: an autoradiographic study. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 3807-16. PMID 8656275 DOI: 10.1523/Jneurosci.16-12-03807.1996 |
0.681 |
|
| 1996 |
Greene JG, Greenamyre JT. Manipulation of membrane potential modulates malonate-induced striatal excitotoxicity in vivo. Journal of Neurochemistry. 66: 637-43. PMID 8592134 DOI: 10.1046/J.1471-4159.1996.66020637.X |
0.641 |
|
| 1996 |
Greene JG, Porter RH, Greenamyre JT. ARL-15896, a novel N-methyl-D-aspartate receptor ion channel antagonist: neuroprotection against mitochondrial metabolic toxicity and regional pharmacology. Experimental Neurology. 137: 66-72. PMID 8566213 DOI: 10.1006/Exnr.1996.0007 |
0.713 |
|
| 1995 |
Blandini F, Porter RH, Greenamyre JT. Autoradiographic study of mitochondrial complex I and glutamate receptors in the basal ganglia of rats after unilateral subthalamic lesion. Neuroscience Letters. 186: 99-102. PMID 7777208 DOI: 10.1016/0304-3940(95)11292-5 |
0.587 |
|
| 1995 |
Hansen JT, Sakai K, Greenamyre JT, Moran S. Sprouting of dopaminergic fibers from spared mesencephalic dopamine neurons in the unilateral partial lesioned rat. Brain Research. 670: 197-204. PMID 7743186 DOI: 10.1016/0006-8993(94)01244-C |
0.395 |
|
| 1995 |
Blandini F, Greenamyre JT. Effect of subthalamic nucleus lesion on mitochondrial enzyme activity in rat basal ganglia. Brain Research. 669: 59-66. PMID 7712165 DOI: 10.1016/0006-8993(94)01233-8 |
0.384 |
|
| 1995 |
Davolio C, Greenamyre JT. Selective vulnerability of the CA1 region of hippocampus to the indirect excitotoxic effects of malonic acid. Neuroscience Letters. 192: 29-32. PMID 7675303 DOI: 10.1016/0304-3940(95)11600-2 |
0.316 |
|
| 1995 |
Messam CA, Greene JG, Greenamyre JT, Robinson MB. Intrastriatal injections of the succinate dehydrogenase inhibitor, malonate, cause a rise in extracellular amino acids that is blocked by MK-801. Brain Research. 684: 221-4. PMID 7583227 DOI: 10.1016/0006-8993(95)00435-S |
0.631 |
|
| 1995 |
Greene JG, Greenamyre JT. Exacerbation of NMDA, AMPA, and L-glutamate excitotoxicity by the succinate dehydrogenase inhibitor malonate. Journal of Neurochemistry. 64: 2332-8. PMID 7536810 DOI: 10.1046/J.1471-4159.1995.64052332.X |
0.629 |
|
| 1995 |
Porter RH, Greenamyre JT. Regional variations in the pharmacology of NMDA receptor channel blockers: implications for therapeutic potential. Journal of Neurochemistry. 64: 614-23. PMID 7530291 DOI: 10.1046/J.1471-4159.1995.64020614.X |
0.519 |
|
| 1995 |
Greene JG, Greenamyre JT. Characterization of the excitotoxic potential of the reversible succinate dehydrogenase inhibitor malonate. Journal of Neurochemistry. 64: 430-6. PMID 7528265 DOI: 10.1046/J.1471-4159.1995.64010430.X |
0.664 |
|
| 1995 |
Angel R, Greenamyre JT. Chronic treatment with thioctic acid does not protect against malonate toxicity in vivo. Neuroscience Letters. 196: 125-7. PMID 7501239 DOI: 10.1016/0304-3940(95)11863-R |
0.305 |
|
| 1994 |
Greenamyre JT, Garcia-Osuna M, Greene JG. The endogenous cofactors, thioctic acid and dihydrolipoic acid, are neuroprotective against NMDA and malonic acid lesions of striatum. Neuroscience Letters. 171: 17-20. PMID 8084483 DOI: 10.1016/0304-3940(94)90593-2 |
0.609 |
|
| 1994 |
Porter RH, Greenamyre JT. Inhibition of autoradiographic MK-801 binding by an endogenous factor. Neuroscience Letters. 169: 105-8. PMID 8047262 DOI: 10.1016/0304-3940(94)90367-0 |
0.518 |
|
| 1994 |
Porter RH, Greene JG, Higgins DS, Greenamyre JT. Polysynaptic regulation of glutamate receptors and mitochondrial enzyme activities in the basal ganglia of rats with unilateral dopamine depletion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 7192-9. PMID 7965108 DOI: 10.1523/Jneurosci.14-11-07192.1994 |
0.8 |
|
| 1994 |
Porter RH, Greenamyre JT. Regional variations in the pharmacology of AMPA receptors as revealed by receptor autoradiography. Brain Research. 664: 202-6. PMID 7534602 |
0.464 |
|
| 1994 |
Greenamyre JT, Porter RH. Anatomy and physiology of glutamate in the CNS. Neurology. 44: S7-13. PMID 7526272 |
0.488 |
|
| 1993 |
Greene JG, Porter RH, Eller RV, Greenamyre JT. Inhibition of succinate dehydrogenase by malonic acid produces an "excitotoxic" lesion in rat striatum. Journal of Neurochemistry. 61: 1151-4. PMID 8360680 DOI: 10.1111/J.1471-4159.1993.Tb03634.X |
0.702 |
|
| 1993 |
Sandhu FA, Porter RH, Eller RV, Zain SB, Salim M, Greenamyre JT. NMDA and AMPA receptors in transgenic mice expressing human beta-amyloid protein. Journal of Neurochemistry. 61: 2286-9. PMID 7504089 DOI: 10.1111/J.1471-4159.1993.Tb07471.X |
0.528 |
|
| 1992 |
Greenamyre JT, Higgins DS, Eller RV. Quantitative autoradiography of dihydrorotenone binding to complex I of the electron transport chain. Journal of Neurochemistry. 59: 746-9. PMID 1629744 |
0.66 |
|
| 1992 |
Albin RL, Greenamyre JT. Alternative excitotoxic hypotheses. Neurology. 42: 733-8. PMID 1314341 DOI: 10.1212/Wnl.42.4.733 |
0.517 |
|
| 1991 |
Greenamyre JT. Neuronal bioenergetic defects, excitotoxicity and Alzheimer's disease: "use it and lose it". Neurobiology of Aging. 12: 334-6; discussion 35. PMID 1961363 DOI: 10.1016/0197-4580(91)90012-9 |
0.389 |
|
| 1991 |
Maragos WF, Greenamyre JT, Chu DC, Penney JB, Young AB. A study of cortical and hippocampal NMDA and PCP receptors following selective cortical and subcortical lesions. Brain Research. 538: 36-45. PMID 1850317 DOI: 10.1016/0006-8993(91)90373-4 |
0.709 |
|
| 1991 |
Kieburtz KD, Epstein LG, Gelbard HA, Greenamyre JT. Excitotoxicity and dopaminergic dysfunction in the acquired immunodeficiency syndrome dementia complex. Therapeutic implications. Archives of Neurology. 48: 1281-4. PMID 1845034 DOI: 10.1001/Archneur.1991.00530240087028 |
0.349 |
|
| 1991 |
Greenamyre JT, O'Brien CF. N-methyl-D-aspartate antagonists in the treatment of Parkinson's disease. Archives of Neurology. 48: 977-81. PMID 1835370 DOI: 10.1001/archneur.1991.00530210109030 |
0.311 |
|
| 1991 |
Klockgether T, Turski L, Honoré T, Zhang ZM, Gash DM, Kurlan R, Greenamyre JT. The AMPA receptor antagonist NBQX has antiparkinsonian effects in monoamine-depleted rats and MPTP-treated monkeys. Annals of Neurology. 30: 717-23. PMID 1662477 DOI: 10.1002/ana.410300513 |
0.408 |
|
| 1991 |
Greenamyre JT. Advances in Neurology, vol 53, Parkinson's Disease: Anatomy, Pathology, and Therapy Archives of Neurology. 48: 897-897. DOI: 10.1001/ARCHNEUR.1991.00530210023004 |
0.384 |
|
| 1990 |
Greenamyre JT, Higgins DS, Young AB, Penney JB. Regional ontogeny of a unique glutamate recognition site in rat brain: an autoradiographic study. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 8: 437-45. PMID 2174635 DOI: 10.1016/0736-5748(90)90076-E |
0.785 |
|
| 1990 |
Penney JB, Maragos WF, Greenamyre JT, Debowey DL, Hollingsworth Z, Young AB. Excitatory amino acid binding sites in the hippocampal region of Alzheimer's disease and other dementias. Journal of Neurology, Neurosurgery, and Psychiatry. 53: 314-20. PMID 2160518 DOI: 10.1136/jnnp.53.4.314 |
0.699 |
|
| 1990 |
Greenamyre JT, Higgins DS, Young AB. Sodium-dependent D-aspartate 'binding' is not a measure of presynaptic neuronal uptake sites in an autoradiographic assay. Brain Research. 511: 310-8. PMID 2159361 DOI: 10.1016/0006-8993(90)90176-C |
0.758 |
|
| 1989 |
Cha JH, Hollingsworth ZR, Greenamyre JT, Young AB. Contamination of commercially available quisqualic acid by glutamate-like and aspartate-like substances. Journal of Neuroscience Methods. 27: 143-8. PMID 2565415 DOI: 10.1016/0165-0270(89)90097-6 |
0.6 |
|
| 1989 |
Greenamyre JT, Young AB. Excitatory amino acids and Alzheimer's disease. Neurobiology of Aging. 10: 593-602. PMID 2554168 DOI: 10.1016/0197-4580(89)90143-7 |
0.628 |
|
| 1989 |
Greenamyre JT, Young AB. Synaptic localization of striatal NMDA, quisqualate and kainate receptors. Neuroscience Letters. 101: 133-7. PMID 2549458 DOI: 10.1016/0304-3940(89)90519-3 |
0.619 |
|
| 1989 |
Greenamyre JT, Young AB. Authors' response to commentaries Neurobiology of Aging. 10: 618-620. DOI: 10.1016/0197-4580(89)90153-X |
0.488 |
|
| 1988 |
Greenamyre JT, Maragos WF, Albin RL, Penney JB, Young AB. Glutamate transmission and toxicity in Alzheimer's disease. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 12: 421-30. PMID 2900537 DOI: 10.1016/0278-5846(88)90102-9 |
0.753 |
|
| 1988 |
Cha JH, Greenamyre JT, Nielsen EO, Penney JB, Young AB. Properties of quisqualate-sensitive L-[3H]glutamate binding sites in rat brain as determined by quantitative autoradiography. Journal of Neurochemistry. 51: 469-78. PMID 2899133 DOI: 10.1111/J.1471-4159.1988.Tb01062.X |
0.691 |
|
| 1988 |
Barks JD, Silverstein FS, Sims K, Greenamyre JT, Johnston MV. Glutamate recognition sites in human fetal brain. Neuroscience Letters. 84: 131-6. PMID 2893319 DOI: 10.1016/0304-3940(88)90396-5 |
0.308 |
|
| 1988 |
Young AB, Greenamyre JT, Hollingsworth Z, Albin R, D'Amato C, Shoulson I, Penney JB. NMDA receptor losses in putamen from patients with Huntington's disease. Science (New York, N.Y.). 241: 981-3. PMID 2841762 DOI: 10.1126/Science.2841762 |
0.733 |
|
| 1987 |
Olson JM, Greenamyre JT, Penney JB, Young AB. Autoradiographic localization of cerebellar excitatory amino acid binding sites in the mouse. Neuroscience. 22: 913-23. PMID 2891079 DOI: 10.1016/0306-4522(87)92969-1 |
0.656 |
|
| 1987 |
Greenamyre JT, Penney JB, D'Amato CJ, Young AB. Dementia of the Alzheimer's type: changes in hippocampal L-[3H]glutamate binding. Journal of Neurochemistry. 48: 543-51. PMID 2878980 DOI: 10.1111/J.1471-4159.1987.Tb04127.X |
0.713 |
|
| 1987 |
Maragos WF, Greenamyre JT, Penney JB, Young AB. Glutamate dysfunction in Alzheimer's disease: an hypothesis Trends in Neurosciences. 10: 65-68. DOI: 10.1016/0166-2236(87)90025-7 |
0.639 |
|
| 1987 |
Maragos WF, Greenamyre JT, Penney JB, Young AB. Reply from W.F. Maragos and colleagues Trends in Neurosciences. 10: 407. DOI: 10.1016/0166-2236(87)90009-9 |
0.488 |
|
| 1986 |
Maragos WF, Chu DC, Greenamyre JT, Penney JB, Young AB. High correlation between the localization of [3H]TCP binding and NMDA receptors. European Journal of Pharmacology. 123: 173-4. PMID 3011454 DOI: 10.1016/0014-2999(86)90703-X |
0.697 |
|
| 1986 |
Greenamyre JT. The role of glutamate in neurotransmission and in neurologic disease. Archives of Neurology. 43: 1058-63. PMID 2428340 DOI: 10.1001/archneur.1986.00520100062016 |
0.383 |
|
| 1985 |
Greenamyre JT, Olson JM, Penney JB, Young AB. Autoradiographic characterization of N-methyl-D-aspartate-, quisqualate- and kainate-sensitive glutamate binding sites. The Journal of Pharmacology and Experimental Therapeutics. 233: 254-63. PMID 2984415 |
0.668 |
|
| 1985 |
Greenamyre JT, Penney JB, Young AB, D'Amato CJ, Hicks SP, Shoulson I. Alterations in L-glutamate binding in Alzheimer's and Huntington's diseases. Science (New York, N.Y.). 227: 1496-9. PMID 2858129 DOI: 10.1126/Science.2858129 |
0.687 |
|
| 1984 |
Greenamyre JT, Young AB, Penney JB. Quantitative autoradiographic distribution of L-[3H]glutamate-binding sites in rat central nervous system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 4: 2133-44. PMID 6088729 DOI: 10.1523/Jneurosci.04-08-02133.1984 |
0.671 |
|
| 1983 |
Greenamyre JT, Young AB, Penney JB. Quantitative autoradiography of L-[3H]glutamate binding to rat brain. Neuroscience Letters. 37: 155-60. PMID 6136011 DOI: 10.1016/0304-3940(83)90146-5 |
0.674 |
|
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