Michael J. Gandal, MD PhD - Publications

Affiliations: 
Psychiatry University of California, Los Angeles, Los Angeles, CA 
Area:
Neurogenetics, Systems Biology, Psychiatric Disease

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Aygün N, Vuong C, Krupa O, Mory J, Le BD, Valone JM, Liang D, Shafie B, Zhang P, Salinda A, Wen C, Gandal MJ, Love MI, de la Torre-Ubieta L, Stein JL. Genetics of cell-type-specific post-transcriptional gene regulation during human neurogenesis. American Journal of Human Genetics. PMID 39168119 DOI: 10.1016/j.ajhg.2024.07.015  0.587
2024 Emani PS, Liu JJ, Clarke D, Jensen M, Warrell J, Gupta C, Meng R, Lee CY, Xu S, Dursun C, Lou S, Chen Y, Chu Z, Galeev T, Hwang A, ... ... Gandal MJ, et al. Single-cell genomics and regulatory networks for 388 human brains. Science (New York, N.Y.). 384: eadi5199. PMID 38781369 DOI: 10.1126/science.adi5199  0.485
2024 Wen C, Margolis M, Dai R, Zhang P, Przytycki PF, Vo DD, Bhattacharya A, Matoba N, Tang M, Jiao C, Kim M, Tsai E, Hoh C, Aygün N, Walker RL, ... ... Gandal MJ, et al. Cross-ancestry atlas of gene, isoform, and splicing regulation in the developing human brain. Science (New York, N.Y.). 384: eadh0829. PMID 38781368 DOI: 10.1126/science.adh0829  0.696
2024 Patowary A, Zhang P, Jops C, Vuong CK, Ge X, Hou K, Kim M, Gong N, Margolis M, Vo D, Wang X, Liu C, Pasaniuc B, Li JJ, Gandal MJ, et al. Developmental isoform diversity in the human neocortex informs neuropsychiatric risk mechanisms. Science (New York, N.Y.). 384: eadh7688. PMID 38781356 DOI: 10.1126/science.adh7688  0.347
2024 Pratt HE, Andrews G, Shedd N, Phalke N, Li T, Pampari A, Jensen M, Wen C, Consortium P, Gandal MJ, Geschwind DH, Gerstein M, Moore J, Kundaje A, Colubri A, et al. Using a comprehensive atlas and predictive models to reveal the complexity and evolution of brain-active regulatory elements. Science Advances. 10: eadj4452. PMID 38781344 DOI: 10.1126/sciadv.adj4452  0.506
2024 Yap CX, Vo DD, Heffel MG, Bhattacharya A, Wen C, Yang Y, Kemper KE, Zeng J, Zheng Z, Zhu Z, Hannon E, Vellame DS, Franklin A, Caggiano C, Wamsley B, ... ... Gandal MJ, et al. Brain cell-type shifts in Alzheimer's disease, autism, and schizophrenia interrogated using methylomics and genetics. Science Advances. 10: eadn7655. PMID 38781333 DOI: 10.1126/sciadv.adn7655  0.528
2024 Emani PS, Liu JJ, Clarke D, Jensen M, Warrell J, Gupta C, Meng R, Lee CY, Xu S, Dursun C, Lou S, Chen Y, Chu Z, Galeev T, Hwang A, ... ... Gandal MJ, et al. Single-cell genomics and regulatory networks for 388 human brains. Biorxiv : the Preprint Server For Biology. PMID 38562822 DOI: 10.1101/2024.03.18.585576  0.481
2023 Bhattacharya A, Vo DD, Jops C, Kim M, Wen C, Hervoso JL, Pasaniuc B, Gandal MJ. Isoform-level transcriptome-wide association uncovers genetic risk mechanisms for neuropsychiatric disorders in the human brain. Nature Genetics. PMID 38036788 DOI: 10.1038/s41588-023-01560-2  0.401
2023 Collado-Torres L, Klei L, Liu C, Kleinman JE, Hyde TM, Geschwind DH, Gandal MJ, Devlin B, Weinberger DR. Comparison of gene expression in living and postmortem human brain. Medrxiv : the Preprint Server For Health Sciences. PMID 37986747 DOI: 10.1101/2023.11.08.23298172  0.487
2023 Warrier V, Stauffer EM, Huang QQ, Wigdor EM, Slob EAW, Seidlitz J, Ronan L, Valk SL, Mallard TT, Grotzinger AD, Romero-Garcia R, Baron-Cohen S, Geschwind DH, Lancaster MA, Murray GK, ... Gandal MJ, et al. Genetic insights into human cortical organization and development through genome-wide analyses of 2,347 neuroimaging phenotypes. Nature Genetics. PMID 37592024 DOI: 10.1038/s41588-023-01475-y  0.516
2023 Patowary A, Zhang P, Jops C, Vuong CK, Ge X, Hou K, Kim M, Gong N, Margolis M, Vo D, Wang X, Liu C, Pasaniuc B, Li JJ, Gandal MJ, et al. Cell-type-specificity of isoform diversity in the developing human neocortex informs mechanisms of neurodevelopmental disorders. Biorxiv : the Preprint Server For Biology. PMID 36993726 DOI: 10.1101/2023.03.25.534016  0.765
2023 Wen C, Margolis M, Dai R, Zhang P, Przytycki PF, Vo DD, Bhattacharya A, Kim M, Matoba N, Tsai E, Hoh C, Jiao C, Aygun N, Walker RL, Chatzinakos C, ... ... Gandal MJ, et al. Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain. Medrxiv : the Preprint Server For Health Sciences. PMID 36945630 DOI: 10.1101/2023.03.03.23286706  0.709
2023 Min S, Gandal MJ, Kopp RF, Liu C, Chen C. No Increased Detection of Nucleic Acids of CNS-related Viruses in the Brains of Patients with Schizophrenia, Bipolar Disorder, and Autism Spectrum Disorder. Schizophrenia Bulletin. PMID 36857101 DOI: 10.1093/schbul/sbad003  0.315
2022 Gandal MJ, Haney JR, Wamsley B, Yap CX, Parhami S, Emani PS, Chang N, Chen GT, Hoftman GD, de Alba D, Ramaswami G, Hartl CL, Bhattacharya A, Luo C, Jin T, et al. Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD. Nature. PMID 36323788 DOI: 10.1038/s41586-022-05377-7  0.802
2022 Hoffman GE, Jaffe AE, Gandal MJ, Collado-Torres L, Sieberts SK, Devlin B, Geschwind DH, Weinberger DR, Roussos P. Comment on: What genes are differentially expressed in individuals with schizophrenia? A systematic review. Molecular Psychiatry. PMID 36123423 DOI: 10.1038/s41380-022-01781-7  0.467
2022 Berto S, Treacher AH, Caglayan E, Luo D, Haney JR, Gandal MJ, Geschwind DH, Montillo AA, Konopka G. Association between resting-state functional brain connectivity and gene expression is altered in autism spectrum disorder. Nature Communications. 13: 3328. PMID 35680911 DOI: 10.1038/s41467-022-31053-5  0.7
2022 Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, ... ... Gandal MJ, et al. Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Nature. PMID 35396580 DOI: 10.1038/s41586-022-04434-5  0.377
2021 Krebs MD, Themudo GE, Benros ME, Mors O, Børglum AD, Hougaard D, Mortensen PB, Nordentoft M, Gandal MJ, Fan CC, Geschwind DH, Schork AJ, Werge T, Thompson WK. Associations between patterns in comorbid diagnostic trajectories of individuals with schizophrenia and etiological factors. Nature Communications. 12: 6617. PMID 34785645 DOI: 10.1038/s41467-021-26903-7  0.468
2021 Vlasova RM, Iosif AM, Ryan AM, Funk LH, Murai T, Chen S, Lesh TA, Rowland DJ, Bennett J, Hogrefe CE, Maddock RJ, Gandal MJ, Geschwind DH, Schumann CM, Van de Water J, et al. Maternal immune activation during pregnancy alters postnatal brain growth and cognitive development in nonhuman primate offspring. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34607967 DOI: 10.1523/JNEUROSCI.0378-21.2021  0.42
2021 López-Aranda MF, Chattopadhyay I, Boxx GM, Fraley ER, Silva TK, Zhou M, Phan M, Herrera I, Taloma S, Mandanas R, Bach K, Gandal M, Geschwind DH, Cheng G, Rzhetsky A, et al. Postnatal immune activation causes social deficits in a mouse model of tuberous sclerosis: Role of microglia and clinical implications. Science Advances. 7: eabf2073. PMID 34533985 DOI: 10.1126/sciadv.abf2073  0.362
2021 Mullins N, Forstner AJ, O'Connell KS, Coombes B, Coleman JRI, Qiao Z, Als TD, Bigdeli TB, Børte S, Bryois J, Charney AW, Drange OK, Gandal MJ, Hagenaars SP, Ikeda M, et al. Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature Genetics. PMID 34002096 DOI: 10.1038/s41588-021-00857-4  0.401
2021 Kim M, Haney JR, Zhang P, Hernandez LM, Wang LK, Perez-Cano L, Loohuis LMO, de la Torre-Ubieta L, Gandal MJ. Brain gene co-expression networks link complement signaling with convergent synaptic pathology in schizophrenia. Nature Neuroscience. PMID 33958802 DOI: 10.1038/s41593-021-00847-z  0.748
2021 Gandal MJ, Geschwind DH. Polygenicity in Psychiatry-Like It or Not, We Have to Understand It. Biological Psychiatry. 89: 2-4. PMID 33272361 DOI: 10.1016/j.biopsych.2020.10.002  0.407
2020 Page NF, Gandal MJ, Estes ML, Cameron S, Buth J, Parhami S, Ramaswami G, Murray K, Amaral DG, Van de Water JA, Schumann CM, Carter CS, Bauman MD, McAllister AK, Geschwind DH. Alterations in Retrotransposition, Synaptic Connectivity, and Myelination Implicated by Transcriptomic Changes Following Maternal Immune Activation in Nonhuman Primates. Biological Psychiatry. PMID 33386132 DOI: 10.1016/j.biopsych.2020.10.016  0.48
2020 Ramaswami G, Won H, Gandal MJ, Haney J, Wang JC, Wong CCY, Sun W, Prabhakar S, Mill J, Geschwind DH. Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism. Nature Communications. 11: 4873. PMID 32978376 DOI: 10.1038/s41467-020-18526-1  0.582
2020 Hernandez LM, Kim M, Hoftman GD, Haney JR, de la Torre-Ubieta L, Pasaniuc B, Gandal MJ. Transcriptomic Insight Into the Polygenic Mechanisms Underlying Psychiatric Disorders. Biological Psychiatry. PMID 32792264 DOI: 10.1016/j.biopsych.2020.06.005  0.798
2020 Walker RL, Ramaswami G, Hartl C, Mancuso N, Gandal MJ, de la Torre-Ubieta L, Pasaniuc B, Stein JL, Geschwind DH. Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms. Cell. 181: 745. PMID 32359439 DOI: 10.1016/j.cell.2020.04.016  0.776
2020 Walker RL, Ramaswami G, Hartl C, Mancuso N, Gandal MJ, Torre-Ubieta L, Pasaniuc B, Stein JL, Geschwind DH. Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms. Cell. 181: 484. PMID 32302575 DOI: 10.1016/j.cell.2020.04.003  0.622
2020 Dahl A, Nguyen K, Cai N, Gandal MJ, Flint J, Zaitlen N. A Robust Method Uncovers Significant Context-Specific Heritability in Diverse Complex Traits. American Journal of Human Genetics. 106: 71-91. PMID 31901249 DOI: 10.1016/J.Ajhg.2019.11.015  0.346
2019 Gandal MJ, Haney JR, Parikshak NN, Leppa V, Ramaswami G, Hartl C, Schork AJ, Appadurai V, Buil A, Werge TM, Liu C, White KP, Geschwind DH. Shared Molecular Neuropathology Across Major Psychiatric Disorders Parallels Polygenic Overlap. Focus (American Psychiatric Publishing). 17: 66-72. PMID 32015716 DOI: 10.1176/appi.focus.17103  0.69
2019 Walker RL, Ramaswami G, Hartl C, Mancuso N, Gandal MJ, de la Torre-Ubieta L, Pasaniuc B, Stein JL, Geschwind DH. Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms. Cell. 179: 750-771.e22. PMID 31626773 DOI: 10.1016/J.Cell.2019.09.021  0.831
2019 Lopez Soto EJ, Gandal MJ, Gonatopoulos-Pournatzis T, Heller EA, Luo D, Zheng S. Mechanisms of Neuronal Alternative Splicing and Strategies for Therapeutic Interventions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 39: 8193-8199. PMID 31619487 DOI: 10.1523/JNEUROSCI.1149-19.2019  0.327
2019 Forsyth JK, Nachun D, Gandal MJ, Geschwind DH, Anderson AE, Coppola G, Bearden CE. Synaptic and Gene Regulatory Mechanisms in Schizophrenia, Autism, and 22q11.2 Copy Number Variant-Mediated Risk for Neuropsychiatric Disorders. Biological Psychiatry. PMID 31500805 DOI: 10.1016/J.Biopsych.2019.06.029  0.607
2019 Lee C, Kang EY, Gandal MJ, Eskin E, Geschwind DH. Profiling allele-specific gene expression in brains from individuals with autism spectrum disorder reveals preferential minor allele usage. Nature Neuroscience. 22: 1521-1532. PMID 31455884 DOI: 10.1038/S41593-019-0461-9  0.575
2019 Ruzzo EK, Pérez-Cano L, Jung JY, Wang LK, Kashef-Haghighi D, Hartl C, Singh C, Xu J, Hoekstra JN, Leventhal O, Leppä VM, Gandal MJ, Paskov K, Stockham N, Polioudakis D, et al. Inherited and De Novo Genetic Risk for Autism Impacts Shared Networks. Cell. 178: 850-866.e26. PMID 31398340 DOI: 10.1016/J.Cell.2019.07.015  0.586
2019 Sharon G, Cruz NJ, Kang DW, Gandal MJ, Wang B, Kim YM, Zink EM, Casey CP, Taylor BC, Lane CJ, Bramer LM, Isern NG, Hoyt DW, Noecker C, Sweredoski MJ, et al. Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice. Cell. 177: 1600-1618.e17. PMID 31150625 DOI: 10.1016/J.Cell.2019.05.004  0.548
2019 Schork AJ, Won H, Appadurai V, Nudel R, Gandal M, Delaneau O, Revsbech Christiansen M, Hougaard DM, Bækved-Hansen M, Bybjerg-Grauholm J, Giørtz Pedersen M, Agerbo E, Bøcker Pedersen C, Neale BM, Daly MJ, et al. A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment. Nature Neuroscience. PMID 30692689 DOI: 10.1038/S41593-018-0320-0  0.6
2019 Forsyth J, Nachun D, Gandal M, Geschwind D, Anderson A, Coppola G, Bearden C. T55SYNAPTIC AND GENE REGULATORY MECHANISMS IN SCHIZOPHRENIA, AUTISM, AND 22Q11.2 CNV MEDIATED RISK FOR NEUROPSYCHIATRIC DISORDERS European Neuropsychopharmacology. 29: S244-S245. DOI: 10.1016/J.Euroneuro.2019.08.254  0.585
2019 Haney J, Parhami S, Ramaswami G, Alba D, Hartl C, Ou J, Parikshak N, Swarup V, Gandal M, Geschwind D. 2 Regional Variation In Transcriptional Dysregulation And Patterning In Postmortem Cerebral Cortex In Asd European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.07.143  0.703
2019 Gandal M, Zhang P, Walker R, Won H, Hadjimichael E, van Bakel H, Haney J, Jaffe A, White K, Peters M, Gerstein M, Liu C, Iakoucheva L, Pinto D, Geschwind D. SA75LARGE-SCALE TRANSCRIPTOME-WIDE CHARACTERIZATION OF ASD, SCHIZOPHRENIA, AND BIPOLAR DISORDER European Neuropsychopharmacology. 29: S1228. DOI: 10.1016/J.Euroneuro.2018.08.297  0.556
2019 Francoeur N, Gandal M, Xu X, Sarpong K, Johnson J, Sklar P, van Bakel H, Geschwind D, Pinto D. ASSESSING THE ROLE OF LONG NONCODING RNAS (LNCRNAS) IN AUTISM SPECTRUM DISORDERS European Neuropsychopharmacology. 29: S960. DOI: 10.1016/j.euroneuro.2017.08.318  0.52
2019 Gandal M, Pinto D, Iakoucheva L, Liu C, Geschwind D. 238. Transcriptome-Wide Isoform-Level Dysregulation in Schizophrenia, Autism, and Bipolar Disorder Biological Psychiatry. 85: S98-S99. DOI: 10.1016/j.biopsych.2019.03.252  0.565
2018 Fan CC, McGrath JJ, Appadurai V, Buil A, Gandal MJ, Schork AJ, Mortensen PB, Agerbo E, Geschwind SA, Geschwind D, Werge T, Thompson WK, Pedersen CB. Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia. Nature Communications. 9: 5296. PMID 30546018 DOI: 10.1038/s41467-018-07708-7  0.536
2018 Wang D, Liu S, Warrell J, Won H, Shi X, Navarro FCP, Clarke D, Gu M, Emani P, Yang YT, Xu M, Gandal MJ, Lou S, Zhang J, Park JJ, et al. Comprehensive functional genomic resource and integrative model for the human brain. Science (New York, N.Y.). 362. PMID 30545857 DOI: 10.1126/Science.Aat8464  0.62
2018 Gandal MJ, Zhang P, Hadjimichael E, Walker RL, Chen C, Liu S, Won H, van Bakel H, Varghese M, Wang Y, Shieh AW, Haney J, Parhami S, Belmont J, Kim M, et al. Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder. Science (New York, N.Y.). 362. PMID 30545856 DOI: 10.1126/Science.Aat8127  0.652
2018 Demontis D, Walters RK, Martin J, Mattheisen M, Als TD, Agerbo E, Baldursson G, Belliveau R, Bybjerg-Grauholm J, Bækvad-Hansen M, Cerrato F, Chambert K, Churchhouse C, Dumont A, Eriksson N, ... Gandal M, et al. Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder. Nature Genetics. PMID 30478444 DOI: 10.1038/S41588-018-0269-7  0.518
2018 Kimura R, Swarup V, Tomiwa K, Gandal MJ, Parikshak NN, Funabiki Y, Nakata M, Awaya T, Kato T, Iida K, Okazaki S, Matsushima K, Kato T, Murai T, Heike T, et al. Integrative network analysis reveals biological pathways associated with Williams syndrome. Journal of Child Psychology and Psychiatry, and Allied Disciplines. PMID 30362171 DOI: 10.1111/Jcpp.12999  0.725
2018 Haney JR, Parhami S, Gandal MJ. Banking on Polygenicity to Disentangle Psychiatric Comorbidity. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. 3: 577-578. PMID 30047475 DOI: 10.1016/j.bpsc.2018.05.006  0.302
2018 Parikshak NN, Swarup V, Belgard TG, Irimia M, Ramaswami G, Gandal MJ, Hartl C, Leppa V, de la Torre Ubieta L, Huang J, Lowe JK, Blencowe BJ, Horvath S, Geschwind DH. Author Correction: Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism. Nature. PMID 29995847 DOI: 10.1038/S41586-018-0295-8  0.763
2018 Schwede M, Nagpal S, Gandal MJ, Parikshak NN, Mirnics K, Geschwind DH, Morrow EM. Strong correlation of downregulated genes related to synaptic transmission and mitochondria in post-mortem autism cerebral cortex. Journal of Neurodevelopmental Disorders. 10: 18. PMID 29859039 DOI: 10.1186/S11689-018-9237-X  0.75
2018 Gandal MJ, Haney JR, Parikshak NN, Leppa V, Ramaswami G, Hartl C, Schork AJ, Appadurai V, Buil A, Werge TM, Liu C, White KP, et al. Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap. Science (New York, N.Y.). 359: 693-697. PMID 29439242 DOI: 10.1126/Science.Aad6469  0.777
2017 Singh T, Walters JTR, Johnstone M, Curtis D, Suvisaari J, Torniainen M, Rees E, Iyegbe C, Blackwood D, McIntosh AM, Kirov G, Geschwind D, Murray RM, Di Forti M, Bramon E, ... Gandal M, et al. The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability. Nature Genetics. PMID 28650482 DOI: 10.1038/Ng.3903  0.57
2016 Parikshak NN, Swarup V, Belgard TG, Irimia M, Ramaswami G, Gandal MJ, Hartl C, Leppa V, Ubieta LT, Huang J, Lowe JK, Blencowe BJ, Horvath S, Geschwind DH. Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism. Nature. PMID 27919067 DOI: 10.1038/Nature20612  0.815
2016 Gandal MJ, Leppa V, Won H, Parikshak NN, Geschwind DH. The road to precision psychiatry: translating genetics into disease mechanisms. Nature Neuroscience. 19: 1397-1407. PMID 27786179 DOI: 10.1038/Nn.4409  0.746
2016 Won H, de la Torre-Ubieta L, Stein JL, Parikshak NN, Huang J, Opland CK, Gandal MJ, Sutton GJ, Hormozdiari F, Lu D, Lee C, Eskin E, Voineagu I, Ernst J, Geschwind DH. Chromosome conformation elucidates regulatory relationships in developing human brain. Nature. PMID 27760116 DOI: 10.1038/Nature19847  0.798
2016 Gandal MJ, Geschwind DH. The Genetics-Driven Revival in Neuropsychiatric Drug Development. Biological Psychiatry. 79: 628-30. PMID 26997117 DOI: 10.1016/j.biopsych.2016.02.024  0.581
2015 Parikshak NN, Gandal MJ, Geschwind DH. Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders. Nature Reviews. Genetics. 16: 441-58. PMID 26149713 DOI: 10.1038/Nrg3934  0.759
2015 Tatard-Leitman VM, Jutzeler CR, Suh J, Saunders JA, Billingslea EN, Morita S, White R, Featherstone RE, Ray R, Ortinski PI, Banerjee A, Gandal MJ, Lin R, Alexandrescu A, Liang Y, et al. Pyramidal cell selective ablation of N-methyl-D-aspartate receptor 1 causes increase in cellular and network excitability. Biological Psychiatry. 77: 556-68. PMID 25156700 DOI: 10.1016/J.Biopsych.2014.06.026  0.745
2014 Port RG, Gandal MJ, Roberts TP, Siegel SJ, Carlson GC. Convergence of circuit dysfunction in ASD: a common bridge between diverse genetic and environmental risk factors and common clinical electrophysiology. Frontiers in Cellular Neuroscience. 8: 414. PMID 25538564 DOI: 10.3389/Fncel.2014.00414  0.644
2014 Billingslea EN, Tatard-Leitman VM, Anguiano J, Jutzeler CR, Suh J, Saunders JA, Morita S, Featherstone RE, Ortinski PI, Gandal MJ, Lin R, Liang Y, Gur RE, Carlson GC, Hahn CG, et al. Parvalbumin cell ablation of NMDA-R1 causes increased resting network excitability with associated social and self-care deficits. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1603-13. PMID 24525709 DOI: 10.1038/Npp.2014.7  0.764
2012 Gandal MJ, Nesbitt AM, McCurdy RM, Alter MD. Measuring the maturity of the fast-spiking interneuron transcriptional program in autism, schizophrenia, and bipolar disorder. Plos One. 7: e41215. PMID 22936973 DOI: 10.1371/journal.pone.0041215  0.47
2012 Gandal MJ, Sisti J, Klook K, Ortinski PI, Leitman V, Liang Y, Thieu T, Anderson R, Pierce RC, Jonak G, Gur RE, Carlson G, Siegel SJ. GABAB-mediated rescue of altered excitatory-inhibitory balance, gamma synchrony and behavioral deficits following constitutive NMDAR-hypofunction. Translational Psychiatry. 2: e142. PMID 22806213 DOI: 10.1038/tp.2012.69  0.603
2012 Saunders JA, Gandal MJ, Roberts TP, Siegel SJ. NMDA antagonist MK801 recreates auditory electrophysiology disruption present in autism and other neurodevelopmental disorders. Behavioural Brain Research. 234: 233-7. PMID 22771812 DOI: 10.1016/J.Bbr.2012.06.032  0.695
2012 Gandal MJ, Anderson RL, Billingslea EN, Carlson GC, Roberts TP, Siegel SJ. Mice with reduced NMDA receptor expression: more consistent with autism than schizophrenia? Genes, Brain, and Behavior. 11: 740-50. PMID 22726567 DOI: 10.1111/j.1601-183X.2012.00816.x  0.628
2012 Cao YA, Featherstone RE, Gandal MJ, Liang Y, Jutzeler C, Saunders J, Tatard-Leitman V, Chen J, Weinberger DR, Lerman C, Siegel SJ. Nicotine normalizes event related potentials in COMT-Val-tg mice and increases gamma and theta spectral density. Behavioral Neuroscience. 126: 332-43. PMID 22309446 DOI: 10.1037/A0027047  0.638
2012 Liao W, Gandal MJ, Ehrlichman RS, Siegel SJ, Carlson GC. MeCP2+/- mouse model of RTT reproduces auditory phenotypes associated with Rett syndrome and replicate select EEG endophenotypes of autism spectrum disorder. Neurobiology of Disease. 46: 88-92. PMID 22249109 DOI: 10.1016/J.Nbd.2011.12.048  0.619
2012 Saunders JA, Gandal MJ, Siegel SJ. NMDA antagonists recreate signal-to-noise ratio and timing perturbations present in schizophrenia. Neurobiology of Disease. 46: 93-100. PMID 22245663 DOI: 10.1016/J.Nbd.2011.12.049  0.655
2012 Gandal MJ, Edgar JC, Klook K, Siegel SJ. Gamma synchrony: towards a translational biomarker for the treatment-resistant symptoms of schizophrenia. Neuropharmacology. 62: 1504-18. PMID 21349276 DOI: 10.1016/j.neuropharm.2011.02.007  0.586
2012 Roberts TPL, Gandal M, Siegel SJ, Vianney–Rodrigues P, Welsh JP. Autism spectrum disorders Translational Neuroscience: Applications in Psychiatry, Neurology, and Neurodevelopmental Disorders. 273-302. DOI: 10.1017/CBO9780511980053.017  0.542
2011 Mehta MV, Gandal MJ, Siegel SJ. mGluR5-antagonist mediated reversal of elevated stereotyped, repetitive behaviors in the VPA model of autism. Plos One. 6: e26077. PMID 22016815 DOI: 10.1371/journal.pone.0026077  0.577
2011 Carlson GC, Talbot K, Halene TB, Gandal MJ, Kazi HA, Schlosser L, Phung QH, Gur RE, Arnold SE, Siegel SJ. Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 108: E962-70. PMID 21969553 DOI: 10.1073/Pnas.1109625108  0.604
2010 Gandal MJ, Edgar JC, Ehrlichman RS, Mehta M, Roberts TP, Siegel SJ. Validating γ oscillations and delayed auditory responses as translational biomarkers of autism. Biological Psychiatry. 68: 1100-6. PMID 21130222 DOI: 10.1016/J.Biopsych.2010.09.031  0.613
2010 Amann LC, Gandal MJ, Halene TB, Ehrlichman RS, White SL, McCarren HS, Siegel SJ. Mouse behavioral endophenotypes for schizophrenia. Brain Research Bulletin. 83: 147-61. PMID 20433908 DOI: 10.1016/J.Brainresbull.2010.04.008  0.611
2010 Amann LC, Gandal MJ, Lin R, Liang Y, Siegel SJ. In vitro-in vivo correlations of scalable PLGA-risperidone implants for the treatment of schizophrenia. Pharmaceutical Research. 27: 1730-7. PMID 20422263 DOI: 10.1007/s11095-010-0152-4  0.688
2010 Lazarewicz MT, Ehrlichman RS, Maxwell CR, Gandal MJ, Finkel LH, Siegel SJ. Ketamine modulates theta and gamma oscillations. Journal of Cognitive Neuroscience. 22: 1452-64. PMID 19583475 DOI: 10.1162/Jocn.2009.21305  0.575
2009 Ehrlichman RS, Gandal MJ, Maxwell CR, Lazarewicz MT, Finkel LH, Contreras D, Turetsky BI, Siegel SJ. N-methyl-d-aspartic acid receptor antagonist-induced frequency oscillations in mice recreate pattern of electrophysiological deficits in schizophrenia. Neuroscience. 158: 705-12. PMID 19015010 DOI: 10.1016/J.Neuroscience.2008.10.031  0.585
2008 Gandal MJ, Ehrlichman RS, Rudnick ND, Siegel SJ. A novel electrophysiological model of chemotherapy-induced cognitive impairments in mice. Neuroscience. 157: 95-104. PMID 18835334 DOI: 10.1016/J.Neuroscience.2008.08.060  0.542
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