Miguel Holmgren - Publications

Affiliations: 
National Institute of Neurological Disorders and Stroke, Bethesda, MD, United States 
Area:
Molecular Neurophysiology
Website:
http://neuroscience.nih.gov/Lab.asp?Org_ID=409

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Miranda P, Holmgren M, Giraldez T. Voltage-dependent dynamics of the BK channel cytosolic gating ring are coupled to the membrane-embedded voltage sensor. Elife. 7. PMID 30526860 DOI: 10.7554/eLife.40664  0.96
2018 Lopez-Rodriguez A, Holmgren M. Deglycosylation of Shaker K channels affects voltage sensing and the open-closed transition. The Journal of General Physiology. PMID 29880580 DOI: 10.1085/jgp.201711958  0.32
2018 Mathur C, Johnson KR, Tong BA, Miranda P, Srikumar D, Basilio D, Latorre R, Bezanilla F, Holmgren M. Demonstration of ion channel synthesis by isolated squid giant axon provides functional evidence for localized axonal membrane protein translation. Scientific Reports. 8: 2207. PMID 29396520 DOI: 10.1038/s41598-018-20684-8  0.96
2016 Miranda P, Giraldez T, Holmgren M. Interactions of divalent cations with calcium binding sites of BK channels reveal independent motions within the gating ring. Proceedings of the National Academy of Sciences of the United States of America. PMID 27872281 DOI: 10.1073/pnas.1611415113  0.96
2015 Castillo JP, Rui H, Basilio D, Das A, Roux B, Latorre R, Bezanilla F, Holmgren M. Mechanism of potassium ion uptake by the Na(+)/K(+)-ATPase. Nature Communications. 6: 7622. PMID 26205423 DOI: 10.1038/ncomms8622  1
2015 Sánchez-Rodríguez JE, Khalili-Araghi F, Miranda P, Roux B, Holmgren M, Bezanilla F. A structural rearrangement of the Na+/K+-ATPase traps ouabain within the external ion permeation pathway. Journal of Molecular Biology. 427: 1335-44. PMID 25637661 DOI: 10.1016/j.jmb.2015.01.011  1
2014 Holmgren M, Rosenthal JJ. Regulation of Ion Channel and Transporter Function Through RNA Editing. Current Issues in Molecular Biology. 17: 23-36. PMID 25347917  1
2014 Venkataraman G, Srikumar D, Holmgren M. Quasi-specific access of the potassium channel inactivation gate. Nature Communications. 5: 4050. PMID 24909510 DOI: 10.1038/ncomms5050  1
2014 Oelstrom K, Goldschen-Ohm MP, Holmgren M, Chanda B. Evolutionarily conserved intracellular gate of voltage-dependent sodium channels. Nature Communications. 5: 3420. PMID 24619022 DOI: 10.1038/ncomms4420  1
2013 Miranda P, Contreras JE, Plested AJ, Sigworth FJ, Holmgren M, Giraldez T. State-dependent FRET reports calcium- and voltage-dependent gating-ring motions in BK channels. Proceedings of the National Academy of Sciences of the United States of America. 110: 5217-22. PMID 23479636 DOI: 10.1073/pnas.1219611110  1
2012 Lopez-Rodriguez A, Holmgren M. Restoration of proper trafficking to the cell surface for membrane proteins harboring cysteine mutations. Plos One. 7: e47693. PMID 23082193 DOI: 10.1371/journal.pone.0047693  1
2012 Gadsby DC, Bezanilla F, Rakowski RF, De Weer P, Holmgren M. The dynamic relationships between the three events that release individual Na⁺ ions from the Na⁺/K⁺-ATPase. Nature Communications. 3: 669. PMID 22334072 DOI: 10.1038/ncomms1673  1
2011 Castillo JP, De Giorgis D, Basilio D, Gadsby DC, Rosenthal JJ, Latorre R, Holmgren M, Bezanilla F. Energy landscape of the reactions governing the Na+ deeply occluded state of the Na+/K+-ATPase in the giant axon of the Humboldt squid. Proceedings of the National Academy of Sciences of the United States of America. 108: 20556-61. PMID 22143771 DOI: 10.1073/pnas.1116439108  1
2011 Sandtner W, Egwolf B, Khalili-Araghi F, Sánchez-Rodríguez JE, Roux B, Bezanilla F, Holmgren M. Ouabain binding site in a functioning Na+/K+ ATPase. The Journal of Biological Chemistry. 286: 38177-83. PMID 21911500 DOI: 10.1074/jbc.M111.267682  1
2011 Gonzalez C, Lopez-Rodriguez A, Srikumar D, Rosenthal JJ, Holmgren M. Editing of human K(V)1.1 channel mRNAs disrupts binding of the N-terminus tip at the intracellular cavity. Nature Communications. 2: 436. PMID 21847110 DOI: 10.1038/ncomms1446  1
2011 Galarza-Muñoz G, Soto-Morales SI, Holmgren M, Rosenthal JJ. Physiological adaptation of an Antarctic Na+/K+-ATPase to the cold. The Journal of Experimental Biology. 214: 2164-74. PMID 21653810 DOI: 10.1242/jeb.048744  1
2010 Colina C, Palavicini JP, Srikumar D, Holmgren M, Rosenthal JJ. Regulation of Na+/K+ ATPase transport velocity by RNA editing. Plos Biology. 8: e1000540. PMID 21124885 DOI: 10.1371/journal.pbio.1000540  1
2010 Contreras JE, Chen J, Lau AY, Jogini V, Roux B, Holmgren M. Voltage profile along the permeation pathway of an open channel. Biophysical Journal. 99: 2863-9. PMID 21044583 DOI: 10.1016/j.bpj.2010.08.053  1
2008 Contreras JE, Srikumar D, Holmgren M. Gating at the selectivity filter in cyclic nucleotide-gated channels. Proceedings of the National Academy of Sciences of the United States of America. 105: 3310-4. PMID 18287006 DOI: 10.1073/pnas.0709809105  1
2007 Rakowski RF, Artigas P, Palma F, Holmgren M, De Weer P, Gadsby DC. Sodium flux ratio in Na/K pump-channels opened by palytoxin. The Journal of General Physiology. 130: 41-54. PMID 17562821 DOI: 10.1085/jgp.200709770  1
2007 Colina C, Rosenthal JJ, DeGiorgis JA, Srikumar D, Iruku N, Holmgren M. Structural basis of Na(+)/K(+)-ATPase adaptation to marine environments. Nature Structural & Molecular Biology. 14: 427-31. PMID 17460695 DOI: 10.1038/nsmb1237  1
2006 Contreras JE, Holmgren M. Access of quaternary ammonium blockers to the internal pore of cyclic nucleotide-gated channels: implications for the location of the gate. The Journal of General Physiology. 127: 481-94. PMID 16606688 DOI: 10.1085/jgp.200509440  1
2006 Holmgren M, Rakowski RF. Charge translocation by the Na+/K+ pump under Na+/Na+ exchange conditions: intracellular Na+ dependence. Biophysical Journal. 90: 1607-16. PMID 16326910 DOI: 10.1529/biophysj.105.072942  1
2004 Bhalla T, Rosenthal JJ, Holmgren M, Reenan R. Control of human potassium channel inactivation by editing of a small mRNA hairpin. Nature Structural & Molecular Biology. 11: 950-6. PMID 15361858 DOI: 10.1038/nsmb825  1
2003 Soler-Llavina GJ, Holmgren M, Swartz KJ. Defining the conductance of the closed state in a voltage-gated K+ channel. Neuron. 38: 61-7. PMID 12691664 DOI: 10.1016/S0896-6273(03)00157-0  1
2003 Holmgren M. Influence of permeant ions on gating in cyclic nucleotide-gated channels. The Journal of General Physiology. 121: 61-72. PMID 12508054 DOI: 10.1085/jgp.20028722  1
2000 Holmgren M, Wagg J, Bezanilla F, Rakowski RF, De Weer P, Gadsby DC. Three distinct and sequential steps in the release of sodium ions by the Na+/K+-ATPase. Nature. 403: 898-901. PMID 10706288 DOI: 10.1038/35002599  0.68
2000 del Camino D, Holmgren M, Liu Y, Yellen G. Blocker protection in the pore of a voltage-gated K+ channel and its structural implications. Nature. 403: 321-5. PMID 10659852 DOI: 10.1038/35002099  1
1998 Holmgren M, Shin KS, Yellen G. The activation gate of a voltage-gated K+ channel can be trapped in the open state by an intersubunit metal bridge. Neuron. 21: 617-21. PMID 9768847 DOI: 10.1016/S0896-6273(00)80571-1  1
1997 Rakowski RF, Bezanilla F, De Weer P, Gadsby DC, Holmgren M, Wagg J. Charge translocation by the Na/K pump. Annals of the New York Academy of Sciences. 834: 231-43. PMID 9405811 DOI: 10.1111/j.1749-6632.1997.tb52254.x  1
1997 Liu Y, Holmgren M, Jurman ME, Yellen G. Gated access to the pore of a voltage-dependent K+ channel. Neuron. 19: 175-84. PMID 9247273 DOI: 10.1016/S0896-6273(00)80357-8  1
1997 Holmgren M, Smith PL, Yellen G. Trapping of organic blockers by closing of voltage-dependent K+ channels: evidence for a trap door mechanism of activation gating. The Journal of General Physiology. 109: 527-35. PMID 9154902 DOI: 10.1085/jgp.109.5.527  1
1996 Holmgren M, Liu Y, Xu Y, Yellen G. On the use of thiol-modifying agents to determine channel topology. Neuropharmacology. 35: 797-804. PMID 8938712 DOI: 10.1016/0028-3908(96)00129-3  1
1996 Holmgren M, Jurman ME, Yellen G. N-type inactivation and the S4-S5 region of the Shaker K+ channel. The Journal of General Physiology. 108: 195-206. PMID 8882863  1
1994 Holmgren M, Rakowski RF. Pre-steady-state transient currents mediated by the Na/K pump in internally perfused Xenopus oocytes. Biophysical Journal. 66: 912-22. PMID 8011923  1
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