| Year |
Citation |
Score |
| 2022 |
Stefanov A, Flannery JG. A Systematic Review of Optogenetic Vision Restoration: History, Challenges, and New Inventions from Bench to Bedside. Cold Spring Harbor Perspectives in Medicine. PMID 36376079 DOI: 10.1101/cshperspect.a041304 |
0.51 |
|
| 2022 |
Leroy BP, Fischer MD, Flannery JG, MacLaren RE, Dalkara D, Scholl HPN, Chung DC, Spera C, Viriato D, Banhazi J. Gene therapy for inherited retinal disease: long-term durability of effect. Ophthalmic Research. PMID 36103843 DOI: 10.1159/000526317 |
0.704 |
|
| 2022 |
Berry MH, Holt A, Broichhagen J, Donthamsetti P, Flannery JG, Isacoff EY. Photopharmacology for vision restoration. Current Opinion in Pharmacology. 65: 102259. PMID 35749908 DOI: 10.1016/j.coph.2022.102259 |
0.476 |
|
| 2022 |
McClements ME, Staurenghi F, Visel M, Flannery JG, MacLaren RE, Cehajic-Kapetanovic J. AAV Induced Expression of Human Rod and Cone Opsin in Bipolar Cells of a Mouse Model of Retinal Degeneration. Biomed Research International. 2021: 1-8. PMID 35465048 DOI: 10.1155/2021/4014797 |
0.524 |
|
| 2022 |
Miyadera K, Santana E, Roszak K, Iffrig S, Visel M, Iwabe S, Boyd RF, Bartoe JT, Sato Y, Gray A, Ripolles-Garcia A, Dufour VL, Byrne LC, Flannery JG, Beltran WA, et al. Targeting ON-bipolar cells by AAV gene therapy stably reverses -congenital stationary night blindness. Proceedings of the National Academy of Sciences of the United States of America. 119: e2117038119. PMID 35316139 DOI: 10.1073/pnas.2117038119 |
0.77 |
|
| 2021 |
Öztürk BE, Johnson ME, Kleyman M, Turunç S, He J, Jabalameli S, Xi Z, Visel M, Dufour VL, Iwabe S, Pompeo Marinho F, Aguirre GD, Sahel JA, Schaffer DV, Pfenning AR, ... Flannery JG, et al. scAAVengr, a transcriptome-based pipeline for quantitative ranking of engineered AAVs with single-cell resolution. Elife. 10. PMID 34664552 DOI: 10.7554/eLife.64175 |
0.772 |
|
| 2021 |
Zin EA, Han D, Tran J, Morisson-Welch N, Visel M, Kuronen M, Flannery JG. Outcomes of progranulin gene therapy in the retina are dependent on time and route of delivery. Molecular Therapy. Methods & Clinical Development. 22: 40-51. PMID 34485593 DOI: 10.1016/j.omtm.2021.05.009 |
0.448 |
|
| 2020 |
Thompson DA, Iannaccone A, Ali RR, Arshavsky VY, Audo I, Bainbridge JWB, Besirli CG, Birch DG, Branham KE, Cideciyan AV, Daiger SP, Dalkara D, Duncan JL, Fahim AT, Flannery JG, et al. Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium. Translational Vision Science & Technology. 9: 2. PMID 32832209 DOI: 10.1167/Tvst.9.7.2 |
0.63 |
|
| 2020 |
Byrne LC, Day TP, Visel M, Fortuny C, Dalkara D, Merigan WH, Schaffer DV, Flannery JG. In vivo directed evolution of AAV in the primate retina. Jci Insight. PMID 32271719 DOI: 10.1172/Jci.Insight.135112 |
0.859 |
|
| 2019 |
Berry MH, Holt A, Salari A, Veit J, Visel M, Levitz J, Aghi K, Gaub BM, Sivyer B, Flannery JG, Isacoff EY. Restoration of high-sensitivity and adapting vision with a cone opsin. Nature Communications. 10: 1221. PMID 30874546 DOI: 10.1038/S41467-019-09124-X |
0.498 |
|
| 2018 |
Baker CK, Flannery JG. Innovative Optogenetic Strategies for Vision Restoration. Frontiers in Cellular Neuroscience. 12: 316. PMID 30297985 DOI: 10.3389/fncel.2018.00316 |
0.32 |
|
| 2018 |
Hardcastle AJ, Sieving PA, Sahel JA, Jacobson SG, Cideciyan AV, Flannery JG, Beltran WA, Aguirre GD. Translational Retinal Research and Therapies. Translational Vision Science & Technology. 7: 8. PMID 30225158 DOI: 10.1167/Tvst.7.5.8 |
0.472 |
|
| 2018 |
Duncan JL, Pierce EA, Laster AM, Daiger SP, Birch DG, Ash JD, Iannaccone A, Flannery JG, Sahel JA, Zack DJ, Zarbin MA. Inherited Retinal Degenerations: Current Landscape and Knowledge Gaps. Translational Vision Science & Technology. 7: 6. PMID 30034950 DOI: 10.1167/Tvst.7.4.6 |
0.484 |
|
| 2018 |
Fortuny C, Flannery JG. Mutation-Independent Gene Therapies for Rod-Cone Dystrophies. Advances in Experimental Medicine and Biology. 1074: 75-81. PMID 29721930 DOI: 10.1007/978-3-319-75402-4_10 |
0.562 |
|
| 2018 |
Elsaeidi F, Macpherson P, Mills EA, Jui J, Flannery JG, Goldman D. Notch suppression collaborates with Ascl1 and Lin28 to unleash a regenerative response in fish retina, but not in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29378863 DOI: 10.1523/Jneurosci.2126-17.2018 |
0.398 |
|
| 2018 |
Day TP, Byrne LC, Flannery JG, Schaffer DV. Screening for Neutralizing Antibodies Against Natural and Engineered AAV Capsids in Nonhuman Primate Retinas. Methods in Molecular Biology (Clifton, N.J.). 1715: 239-249. PMID 29188518 DOI: 10.1007/978-1-4939-7522-8_17 |
0.818 |
|
| 2018 |
Gaub BM, Berry MH, Visel M, Holt A, Isacoff EY, Flannery JG. Optogenetic Retinal Gene Therapy with the Light Gated GPCR Vertebrate Rhodopsin. Methods in Molecular Biology (Clifton, N.J.). 1715: 177-189. PMID 29188513 DOI: 10.1007/978-1-4939-7522-8_12 |
0.538 |
|
| 2017 |
Berry MH, Holt A, Levitz J, Broichhagen J, Gaub BM, Visel M, Stanley C, Aghi K, Kim YJ, Trauner D, Flannery J, Isacoff EY. Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor. Nature Communications. 8: 1862. PMID 29192252 DOI: 10.1038/S41467-017-01990-7 |
0.547 |
|
| 2017 |
LaVail MM, Nishikawa S, Steinberg RH, Naash MI, Duncan JL, Trautmann N, Matthes MT, Yasumura D, Lau-Villacorta C, Chen J, Peterson WM, Yang H, Flannery JG. Phenotypic characterization of P23H and S334ter rhodopsin transgenic rat models of inherited retinal degeneration. Experimental Eye Research. PMID 29122605 DOI: 10.1016/J.Exer.2017.10.023 |
0.542 |
|
| 2017 |
Hickey DG, Edwards TL, Barnard AR, Singh MS, de Silva SR, McClements ME, Flannery JG, Hankins MW, MacLaren RE. Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina. Gene Therapy. PMID 28872643 DOI: 10.1038/gt.2017.85 |
0.625 |
|
| 2016 |
Yao K, Qiu S, Tian L, Snider WD, Flannery JG, Schaffer DV, Chen B. Wnt Regulates Proliferation and Neurogenic Potential of Müller Glial Cells via a Lin28/let-7 miRNA-Dependent Pathway in Adult Mammalian Retinas. Cell Reports. 17: 165-78. PMID 27681429 DOI: 10.1016/J.Celrep.2016.08.078 |
0.559 |
|
| 2016 |
Byrne LC, Visel M, Dufour V, Marinho FP, Aguirre GD, Beltran WA, Flannery JG, Schaffer DV. 617. Identification of Novel AAV Capsid Variants with Enhanced Tropism for the Canine Outer Retina Following Intravitreal Delivery Molecular Therapy. 24: S244-S245. DOI: 10.1016/S1525-0016(16)33425-6 |
0.722 |
|
| 2015 |
Shen SQ, Myers CA, Hughes AE, Byrne LC, Flannery JG, Corbo JC. Massively parallel cis-regulatory analysis in the mammalian central nervous system. Genome Research. PMID 26576614 DOI: 10.1101/Gr.193789.115 |
0.726 |
|
| 2015 |
Rosa JM, Bos R, Sack GS, Fortuny C, Agarwal A, Bergles DE, Flannery JG, Feller MB. Neuron-glia signaling in developing retina mediated by neurotransmitter spillover. Elife. 4. PMID 26274565 DOI: 10.7554/Elife.09590 |
0.421 |
|
| 2015 |
Gaub BM, Berry MH, Holt AE, Isacoff EY, Flannery JG. Optogenetic Vision Restoration Using Rhodopsin for Enhanced Sensitivity. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 1562-71. PMID 26137852 DOI: 10.1038/mt.2015.121 |
0.512 |
|
| 2015 |
Zawadzki RJ, Zhang P, Zam A, Miller EB, Goswami M, Wang X, Jonnal RS, Lee SH, Kim DY, Flannery JG, Werner JS, Burns ME, Pugh EN. Adaptive-optics SLO imaging combined with widefield OCT and SLO enables precise 3D localization of fluorescent cells in the mouse retina. Biomedical Optics Express. 6: 2191-210. PMID 26114038 DOI: 10.1364/Boe.6.002191 |
0.479 |
|
| 2015 |
Pellissier LP, Quinn PM, Alves CH, Vos RM, Klooster J, Flannery JG, Heimel JA, Wijnholds J. Gene therapy into photoreceptors and Müller glial cells restores retinal structure and function in CRB1 retinitis pigmentosa mouse models. Human Molecular Genetics. 24: 3104-18. PMID 25701872 DOI: 10.1093/Hmg/Ddv062 |
0.638 |
|
| 2015 |
Thompson DA, Ali RR, Banin E, Branham KE, Flannery JG, Gamm DM, Hauswirth WW, Heckenlively JR, Iannaccone A, Jayasundera KT, Khan NW, Molday RS, Pennesi ME, Reh TA, Weleber RG, et al. Advancing therapeutic strategies for inherited retinal degeneration: recommendations from the Monaciano Symposium. Investigative Ophthalmology & Visual Science. 56: 918-31. PMID 25667399 DOI: 10.1167/Iovs.14-16049 |
0.53 |
|
| 2015 |
Xue Y, Shen SQ, Jui J, Rupp AC, Byrne LC, Hattar S, Flannery JG, Corbo JC, Kefalov VJ. CRALBP supports the mammalian retinal visual cycle and cone vision. The Journal of Clinical Investigation. 125: 727-38. PMID 25607845 DOI: 10.1172/Jci79651 |
0.788 |
|
| 2015 |
Kotterman MA, Yin L, Strazzeri JM, Flannery JG, Merigan WH, Schaffer DV. Antibody neutralization poses a barrier to intravitreal adeno-associated viral vector gene delivery to non-human primates. Gene Therapy. 22: 116-26. PMID 25503696 DOI: 10.1038/Gt.2014.115 |
0.61 |
|
| 2015 |
Byrne LC, Dalkara D, Luna G, Fisher SK, Clérin E, Sahel JA, Léveillard T, Flannery JG. Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration. The Journal of Clinical Investigation. 125: 105-16. PMID 25415434 DOI: 10.1172/Jci65654 |
0.855 |
|
| 2015 |
Byrne LC, Lin YJ, Lee T, Schaffer DV, Flannery JG. The expression pattern of systemically injected AAV9 in the developing mouse retina is determined by age. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 290-6. PMID 25224467 DOI: 10.1038/Mt.2014.181 |
0.838 |
|
| 2015 |
Rosa JM, Bos R, Sack GS, Fortuny C, Agarwal A, Bergles DE, Flannery JG, Feller MB. Author response: Neuron-glia signaling in developing retina mediated by neurotransmitter spillover Elife. DOI: 10.7554/Elife.09590.019 |
0.359 |
|
| 2014 |
Pellissier LP, Hoek RM, Vos RM, Aartsen WM, Klimczak RR, Hoyng SA, Flannery JG, Wijnholds J. Specific tools for targeting and expression in Müller glial cells. Molecular Therapy. Methods & Clinical Development. 1: 14009. PMID 26015954 DOI: 10.1038/Mtm.2014.9 |
0.835 |
|
| 2014 |
Gaub BM, Berry MH, Holt AE, Reiner A, Kienzler MA, Dolgova N, Nikonov S, Aguirre GD, Beltran WA, Flannery JG, Isacoff EY. Restoration of visual function by expression of a light-gated mammalian ion channel in retinal ganglion cells or ON-bipolar cells. Proceedings of the National Academy of Sciences of the United States of America. 111: E5574-83. PMID 25489083 DOI: 10.1073/Pnas.1414162111 |
0.574 |
|
| 2014 |
Vlasits AL, Bos R, Morrie RD, Fortuny C, Flannery JG, Feller MB, Rivlin-Etzion M. Visual stimulation switches the polarity of excitatory input to starburst amacrine cells. Neuron. 83: 1172-84. PMID 25155960 DOI: 10.1016/J.Neuron.2014.07.037 |
0.344 |
|
| 2014 |
Yin L, Masella B, Dalkara D, Zhang J, Flannery JG, Schaffer DV, Williams DR, Merigan WH. Imaging light responses of foveal ganglion cells in the living macaque eye. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6596-605. PMID 24806684 DOI: 10.1523/Jneurosci.4438-13.2014 |
0.765 |
|
| 2014 |
Byrne LC, Oztürk BE, Lee T, Fortuny C, Visel M, Dalkara D, Schaffer DV, Flannery JG. Retinoschisin gene therapy in photoreceptors, Müller glia or all retinal cells in the Rs1h-/- mouse. Gene Therapy. 21: 585-92. PMID 24694538 DOI: 10.1038/Gt.2014.31 |
0.867 |
|
| 2014 |
Day TP, Byrne LC, Schaffer DV, Flannery JG. Advances in AAV vector development for gene therapy in the retina. Advances in Experimental Medicine and Biology. 801: 687-93. PMID 24664759 DOI: 10.1007/978-1-4614-3209-8_86 |
0.844 |
|
| 2014 |
Alves CH, Pellissier LP, Vos RM, Garcia Garrido M, Sothilingam V, Seide C, Beck SC, Klooster J, Furukawa T, Flannery JG, Verhaagen J, Seeliger MW, Wijnholds J. Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa. Human Molecular Genetics. 23: 3384-401. PMID 24493795 DOI: 10.1093/Hmg/Ddu048 |
0.629 |
|
| 2014 |
Wang H, Yang Z, Jiang Y, Flannery J, Hammond S, Kafri T, Vemuri SK, Jones B, Hartnett ME. Quantitative analyses of retinal vascular area and density after different methods to reduce VEGF in a rat model of retinopathy of prematurity. Investigative Ophthalmology & Visual Science. 55: 737-44. PMID 24425858 DOI: 10.1167/Iovs.13-13429 |
0.4 |
|
| 2014 |
Jiang Y, Wang H, Culp D, Yang Z, Fotheringham L, Flannery J, Hammond S, Kafri T, Hartnett ME. Targeting Müller cell-derived VEGF164 to reduce intravitreal neovascularization in the rat model of retinopathy of prematurity. Investigative Ophthalmology & Visual Science. 55: 824-31. PMID 24425851 DOI: 10.1167/Iovs.13-13755 |
0.363 |
|
| 2014 |
Vacca O, Darche M, Schaffer DV, Flannery JG, Sahel JA, Rendon A, Dalkara D. AAV-mediated gene delivery in Dp71-null mouse model with compromised barriers. Glia. 62: 468-76. PMID 24382652 DOI: 10.1002/Glia.22617 |
0.796 |
|
| 2013 |
Byrne LC, Khalid F, Lee T, Zin EA, Greenberg KP, Visel M, Schaffer DV, Flannery JG. AAV-mediated, optogenetic ablation of Müller Glia leads to structural and functional changes in the mouse retina. Plos One. 8: e76075. PMID 24086689 DOI: 10.1371/Journal.Pone.0076075 |
0.86 |
|
| 2013 |
Wang H, Smith GW, Yang Z, Jiang Y, McCloskey M, Greenberg K, Geisen P, Culp WD, Flannery J, Kafri T, Hammond S, Hartnett ME. Short hairpin RNA-mediated knockdown of VEGFA in Müller cells reduces intravitreal neovascularization in a rat model of retinopathy of prematurity. The American Journal of Pathology. 183: 964-74. PMID 23972394 DOI: 10.1016/J.Ajpath.2013.05.011 |
0.79 |
|
| 2013 |
Pernet V, Joly S, Jordi N, Dalkara D, Guzik-Kornacka A, Flannery JG, Schwab ME. Misguidance and modulation of axonal regeneration by Stat3 and Rho/ROCK signaling in the transparent optic nerve. Cell Death & Disease. 4: e734. PMID 23868067 DOI: 10.1038/Cddis.2013.266 |
0.622 |
|
| 2013 |
Dalkara D, Byrne LC, Klimczak RR, Visel M, Yin L, Merigan WH, Flannery JG, Schaffer DV. In vivo-directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous. Science Translational Medicine. 5: 189ra76. PMID 23761039 DOI: 10.1126/Scitranslmed.3005708 |
0.856 |
|
| 2013 |
Pernet V, Joly S, Dalkara D, Jordi N, Schwarz O, Christ F, Schaffer DV, Flannery JG, Schwab ME. Long-distance axonal regeneration induced by CNTF gene transfer is impaired by axonal misguidance in the injured adult optic nerve. Neurobiology of Disease. 51: 202-13. PMID 23194670 DOI: 10.1016/J.Nbd.2012.11.011 |
0.699 |
|
| 2013 |
Flannery JG, Visel M. Adeno-associated viral vectors for gene therapy of inherited retinal degenerations. Methods in Molecular Biology (Clifton, N.J.). 935: 351-69. PMID 23150381 DOI: 10.1007/978-1-62703-080-9_25 |
0.514 |
|
| 2013 |
Yin L, Masella BD, Geng Y, Dalkara D, Osakada F, Sharma R, Zhang J, Cetin AH, Callaway EM, Flannery JG, Schaffer DV, Williams DR, Merigan WH. Optical recording of the light response of ganglion cells in the living eye Optics Infobase Conference Papers. DOI: 10.1364/Fio.2013.Ftu4I.3 |
0.743 |
|
| 2012 |
Lee SH, Kwan AC, Zhang S, Phoumthipphavong V, Flannery JG, Masmanidis SC, Taniguchi H, Huang ZJ, Zhang F, Boyden ES, Deisseroth K, Dan Y. Activation of specific interneurons improves V1 feature selectivity and visual perception. Nature. 488: 379-83. PMID 22878719 DOI: 10.1038/Nature11312 |
0.473 |
|
| 2012 |
Zallocchi M, Meehan DT, Delimont D, Rutledge J, Gratton MA, Flannery J, Cosgrove D. Role for a novel Usher protein complex in hair cell synaptic maturation. Plos One. 7: e30573. PMID 22363448 DOI: 10.1371/journal.pone.0030573 |
0.337 |
|
| 2012 |
Pernet V, Joly S, Dalkara D, Schwarz O, Christ F, Schaffer D, Flannery JG, Schwab ME. Neuronal Nogo-A upregulation does not contribute to ER stress-associated apoptosis but participates in the regenerative response in the axotomized adult retina. Cell Death and Differentiation. 19: 1096-108. PMID 22193546 DOI: 10.1038/Cdd.2011.191 |
0.726 |
|
| 2012 |
Dalkara D, Byrne LC, Lee T, Hoffmann NV, Schaffer DV, Flannery JG. Enhanced gene delivery to the neonatal retina through systemic administration of tyrosine-mutated AAV9. Gene Therapy. 19: 176-81. PMID 22011645 DOI: 10.1038/Gt.2011.163 |
0.867 |
|
| 2012 |
Yin L, Masella B, Dalkara D, Flannery JG, Schaffer DV, Williams DR, Merigan WH. In vivo imaging of ganglion cell physiology in macaque fovea using a calcium indicator Journal of Vision. 12: 55-55. DOI: 10.1167/12.14.55 |
0.693 |
|
| 2011 |
Caporale N, Kolstad KD, Lee T, Tochitsky I, Dalkara D, Trauner D, Kramer R, Dan Y, Isacoff EY, Flannery JG. LiGluR restores visual responses in rodent models of inherited blindness. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1212-9. PMID 21610698 DOI: 10.1038/Mt.2011.103 |
0.843 |
|
| 2011 |
Dalkara D, Kolstad KD, Guerin KI, Hoffmann NV, Visel M, Klimczak RR, Schaffer DV, Flannery JG. AAV mediated GDNF secretion from retinal glia slows down retinal degeneration in a rat model of retinitis pigmentosa. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1602-8. PMID 21522134 DOI: 10.1038/Mt.2011.62 |
0.842 |
|
| 2011 |
Yin L, Greenberg K, Hunter JJ, Dalkara D, Kolstad KD, Masella BD, Wolfe R, Visel M, Stone D, Libby RT, Diloreto D, Schaffer D, Flannery J, Williams DR, Merigan WH. Intravitreal injection of AAV2 transduces macaque inner retina. Investigative Ophthalmology & Visual Science. 52: 2775-83. PMID 21310920 DOI: 10.1167/Iovs.10-6250 |
0.83 |
|
| 2011 |
Västinsalo H, Jalkanen R, Dinculescu A, Isosomppi J, Geller S, Flannery JG, Hauswirth WW, Sankila EM. Alternative splice variants of the USH3A gene Clarin 1 (CLRN1). European Journal of Human Genetics : Ejhg. 19: 30-5. PMID 20717163 DOI: 10.1038/Ejhg.2010.140 |
0.412 |
|
| 2010 |
Kolstad KD, Dalkara D, Guerin K, Visel M, Hoffmann N, Schaffer DV, Flannery JG. Changes in adeno-associated virus-mediated gene delivery in retinal degeneration. Human Gene Therapy. 21: 571-8. PMID 20021232 DOI: 10.1089/Hum.2009.194 |
0.838 |
|
| 2010 |
Liu H, Wang M, Xia CH, Du X, Flannery JG, Ridge KD, Beutler B, Gong X. Severe retinal degeneration caused by a novel rhodopsin mutation. Investigative Ophthalmology & Visual Science. 51: 1059-65. PMID 19741247 DOI: 10.1167/Iovs.09-3585 |
0.4 |
|
| 2010 |
Geng Y, Porter J, Greenberg KP, Wolfe R, Gray DC, Hunter JJ, Dubra A, Masella BD, Flannery JG, Williams DR. Adaptive optics imaging of microscopic structures in rat retina in vivo Journal of Vision. 8: 18-18. DOI: 10.1167/8.17.18 |
0.743 |
|
| 2010 |
Yin L, Dalkara D, Greenberg K, Hunter JJ, Masella BD, Visel M, DiLoreto Jr. D, Flannery J, Williams DR, Merigan WH. AAV-mediated gene delivery to retinal ganglion cells in the macaque eye Journal of Vision. 10: 66-66. DOI: 10.1167/10.15.66 |
0.858 |
|
| 2009 |
Klimczak RR, Koerber JT, Dalkara D, Flannery JG, Schaffer DV. A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells. Plos One. 4: e7467. PMID 19826483 DOI: 10.1371/Journal.Pone.0007467 |
0.851 |
|
| 2009 |
Tackenberg MA, Tucker BA, Swift JS, Jiang C, Redenti S, Greenberg KP, Flannery JG, Reichenbach A, Young MJ. Müller cell activation, proliferation and migration following laser injury. Molecular Vision. 15: 1886-96. PMID 19768129 |
0.794 |
|
| 2009 |
Geller SF, Guerin KI, Visel M, Pham A, Lee ES, Dror AA, Avraham KB, Hayashi T, Ray CA, Reh TA, Bermingham-McDonogh O, Triffo WJ, Bao S, Isosomppi J, Västinsalo H, ... ... Flannery JG, et al. CLRN1 is nonessential in the mouse retina but is required for cochlear hair cell development. Plos Genetics. 5: e1000607. PMID 19680541 DOI: 10.1371/Journal.Pgen.1000607 |
0.845 |
|
| 2009 |
Dalkara D, Kolstad KD, Caporale N, Visel M, Klimczak RR, Schaffer DV, Flannery JG. Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2096-102. PMID 19672248 DOI: 10.1038/Mt.2009.181 |
0.841 |
|
| 2009 |
Koerber JT, Klimczak R, Jang JH, Dalkara D, Flannery JG, Schaffer DV. Molecular evolution of adeno-associated virus for enhanced glial gene delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2088-95. PMID 19672246 DOI: 10.1038/Mt.2009.184 |
0.826 |
|
| 2009 |
Geng Y, Greenberg KP, Wolfe R, Gray DC, Hunter JJ, Dubra A, Flannery JG, Williams DR, Porter J. In vivo imaging of microscopic structures in the rat retina. Investigative Ophthalmology & Visual Science. 50: 5872-9. PMID 19578019 DOI: 10.1167/Iovs.09-3675 |
0.812 |
|
| 2009 |
Tian G, Zhou Y, Hajkova D, Miyagi M, Dinculescu A, Hauswirth WW, Palczewski K, Geng R, Alagramam KN, Isosomppi J, Sankila EM, Flannery JG, Imanishi Y. Clarin-1, encoded by the Usher Syndrome III causative gene, forms a membranous microdomain: possible role of clarin-1 in organizing the actin cytoskeleton. The Journal of Biological Chemistry. 284: 18980-93. PMID 19423712 DOI: 10.1074/Jbc.M109.003160 |
0.316 |
|
| 2009 |
Geng R, Geller SF, Hayashi T, Ray CA, Reh TA, Bermingham-McDonogh O, Jones SM, Wright CG, Melki S, Imanishi Y, Palczewski K, Alagramam KN, Flannery JG. Usher syndrome IIIA gene clarin-1 is essential for hair cell function and associated neural activation. Human Molecular Genetics. 18: 2748-60. PMID 19414487 DOI: 10.1093/Hmg/Ddp210 |
0.354 |
|
| 2008 |
Guerin K, Gregory-Evans CY, Hodges MD, Moosajee M, Mackay DS, Gregory-Evans K, Flannery JG. Systemic aminoglycoside treatment in rodent models of retinitis pigmentosa. Experimental Eye Research. 87: 197-207. PMID 18644591 DOI: 10.1016/J.Exer.2008.05.016 |
0.842 |
|
| 2007 |
Paskowitz DM, Greenberg KP, Yasumura D, Grimm D, Yang H, Duncan JL, Kay MA, Lavail MM, Flannery JG, Vollrath D. Rapid and stable knockdown of an endogenous gene in retinal pigment epithelium. Human Gene Therapy. 18: 871-80. PMID 17892416 DOI: 10.1089/Hum.2007.065 |
0.827 |
|
| 2007 |
Chen Y, Hu Y, Lu K, Flannery JG, Ma JX. Very low density lipoprotein receptor, a negative regulator of the wnt signaling pathway and choroidal neovascularization. The Journal of Biological Chemistry. 282: 34420-8. PMID 17890782 DOI: 10.1074/jbc.M611289200 |
0.358 |
|
| 2007 |
Geller SF, Ge PS, Visel M, Greenberg KP, Flannery JG. Functional promoter testing using a modified lentiviral transfer vector. Molecular Vision. 13: 730-9. PMID 17563724 |
0.776 |
|
| 2007 |
Lee ES, Flannery JG. Transport of truncated rhodopsin and its effects on rod function and degeneration. Investigative Ophthalmology & Visual Science. 48: 2868-76. PMID 17525223 DOI: 10.1167/iovs.06-0035 |
0.476 |
|
| 2007 |
Szobota S, Gorostiza P, Del Bene F, Wyart C, Fortin DL, Kolstad KD, Tulyathan O, Volgraf M, Numano R, Aaron HL, Scott EK, Kramer RH, Flannery J, Baier H, Trauner D, et al. Remote control of neuronal activity with a light-gated glutamate receptor. Neuron. 54: 535-45. PMID 17521567 DOI: 10.1016/J.Neuron.2007.05.010 |
0.748 |
|
| 2007 |
Aarnisalo AA, Pietola L, Joensuu J, Isosomppi J, Aarnisalo P, Dinculescu A, Lewin AS, Flannery J, Hauswirth WW, Sankila EM, Jero J. Anti-clarin-1 AAV-delivered ribozyme induced apoptosis in the mouse cochlea Hearing Research. 230: 9-16. PMID 17493778 DOI: 10.1016/J.Heares.2007.03.004 |
0.442 |
|
| 2007 |
Greenberg KP, Geller SF, Schaffer DV, Flannery JG. Targeted transgene expression in muller glia of normal and diseased retinas using lentiviral vectors. Investigative Ophthalmology & Visual Science. 48: 1844-52. PMID 17389520 DOI: 10.1167/Iovs.05-1570 |
0.851 |
|
| 2006 |
Greenberg KP, Lee ES, Schaffer DV, Flannery JG. Gene delivery to the retina using lentiviral vectors. Advances in Experimental Medicine and Biology. 572: 255-66. PMID 17249582 DOI: 10.1007/0-387-32442-9_36 |
0.856 |
|
| 2006 |
Lee ES, Burnside B, Flannery JG. Characterization of peripherin/rds and rom-1 transport in rod photoreceptors of transgenic and knockout animals. Investigative Ophthalmology & Visual Science. 47: 2150-60. PMID 16639027 DOI: 10.1167/iovs.05-0919 |
0.349 |
|
| 2006 |
Flannery JG, Greenberg KP. Looking within for vision. Neuron. 50: 1-3. PMID 16600846 DOI: 10.1016/j.neuron.2006.03.027 |
0.829 |
|
| 2006 |
Flannery JG, Greenberg KP. Looking within for Vision (DOI:10.1016/j.neuron.2006.03.027) Neuron. 50: 341. DOI: 10.1016/j.neuron.2006.04.003 |
0.694 |
|
| 2004 |
Hauswirth WW, Li Q, Raisler B, Timmers AM, Berns KI, Flannery JG, LaVail MM, Lewin AS. Range of retinal diseases potentially treatable by AAV-vectored gene therapy. Novartis Foundation Symposium. 255: 179-88; discussion 1. PMID 14750604 DOI: 10.1002/0470092645.Ch14 |
0.61 |
|
| 2003 |
Lau D, Flannery J. Viral-mediated FGF-2 treatment of the constant light damage model of photoreceptor degeneration. Documenta Ophthalmologica. Advances in Ophthalmology. 106: 89-98. PMID 12675490 DOI: 10.1023/A:1022481306146 |
0.525 |
|
| 2002 |
Adato A, Vreugde S, Joensuu T, Avidan N, Hamalainen R, Belenkiy O, Olender T, Bonne-Tamir B, Ben-Asher E, Espinos C, Millán JM, Lehesjoki AE, Flannery JG, Avraham KB, Pietrokovski S, et al. USH3A transcripts encode clarin-1, a four-transmembrane-domain protein with a possible role in sensory synapses. European Journal of Human Genetics : Ejhg. 10: 339-50. PMID 12080385 DOI: 10.1038/Sj.Ejhg.5200831 |
0.383 |
|
| 2001 |
McGee Sanftner LH, Abel H, Hauswirth WW, Flannery JG. Glial cell line derived neurotrophic factor delays photoreceptor degeneration in a transgenic rat model of retinitis pigmentosa. Molecular Therapy : the Journal of the American Society of Gene Therapy. 4: 622-9. PMID 11735347 DOI: 10.1006/Mthe.2001.0498 |
0.614 |
|
| 2001 |
McGee Sanftner LH, Rendahl KG, Quiroz D, Coyne M, Ladner M, Manning WC, Flannery JG. Recombinant AAV-mediated delivery of a tet-inducible reporter gene to the rat retina. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 688-96. PMID 11356074 DOI: 10.1006/mthe.2001.0308 |
0.589 |
|
| 2001 |
Green ES, Rendahl KG, Zhou S, Ladner M, Coyne M, Srivastava R, Manning WC, Flannery JG. Two animal models of retinal degeneration are rescued by recombinant adeno-associated virus-mediated production of FGF-5 and FGF-18. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 507-15. PMID 11319911 DOI: 10.1006/Mthe.2001.0289 |
0.496 |
|
| 2001 |
Hauswirth WW, LaVail MM, Flannery JG, Lewin AS. Viral-vectored ribozymes as therapy for autosomal dominant retinal disease Clinical Neuroscience Research. 1: 118-126. DOI: 10.1016/S1566-2772(00)00010-4 |
0.573 |
|
| 2001 |
Hauswirth WW, LaVail MM, Flannery JG, Lewin AS. Viral-vectored ribozymes as therapy for autosomal dominant retinal disease Clinical Neuroscience Research. 1: 118-126. DOI: 10.1016/S1566-2772(00)00010-4 |
0.432 |
|
| 2000 |
Yoshikawa M, Anderson K, Sakaguchi H, Flannery JG, Fitzgerald PG, Ishida AT. Voltage-gated Na+ channel EOIII-segment-like immunoreactivity in fish retinal ganglion cells. Visual Neuroscience. 17: 647-55. PMID 11016582 DOI: 10.1017/S0952523800174139 |
0.444 |
|
| 2000 |
Lau D, McGee LH, Zhou S, Rendahl KG, Manning WC, Escobedo JA, Flannery JG. Retinal degeneration is slowed in transgenic rats by AAV-mediated delivery of FGF-2. Investigative Ophthalmology & Visual Science. 41: 3622-33. PMID 11006261 |
0.475 |
|
| 2000 |
LaVail MM, Yasumura D, Matthes MT, Drenser KA, Flannery JG, Lewin AS, Hauswirth WW. Ribozyme rescue of photoreceptor cells in P23H transgenic rats: long-term survival and late-stage therapy. Proceedings of the National Academy of Sciences of the United States of America. 97: 11488-93. PMID 11005848 DOI: 10.1073/Pnas.210319397 |
0.482 |
|
| 2000 |
Hauswirth WW, LaVail MM, Flannery JG, Lewin AS. Ribozyme gene therapy for autosomal dominant retinal disease. Clinical Chemistry and Laboratory Medicine : Cclm / Fescc. 38: 147-53. PMID 10834402 DOI: 10.1515/Cclm.2000.022 |
0.611 |
|
| 2000 |
Green ES, Menz MD, LaVail MM, Flannery JG. Characterization of rhodopsin mis-sorting and constitutive activation in a transgenic rat model of retinitis pigmentosa. Investigative Ophthalmology & Visual Science. 41: 1546-53. PMID 10798675 |
0.396 |
|
| 1999 |
Flannery JG. Transgenic Animal Models for the Study of Inherited Retinal Dystrophies. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 40: 51-58. PMID 11533514 DOI: 10.1093/Ilar.40.2.51 |
0.551 |
|
| 1998 |
Lewin AS, Drenser KA, Hauswirth WW, Nishikawa S, Yasumura D, Flannery JG, LaVail MM. Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa. Nature Medicine. 4: 967-71. PMID 9701253 DOI: 10.1038/Nm0898-967 |
0.559 |
|
| 1998 |
Lewin A, Drenser K, Hauswirth W, Nishikawa S, Yasumura D, Flannery J, LaVail M. Erratum: Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa Nature Medicine. 4: 1081-1081. DOI: 10.1038/2077 |
0.467 |
|
| 1997 |
Milam AH, Possin DE, Huang J, Fariss RN, Flannery JG, Saari JC. Characterization of aldehyde dehydrogenase-positive amacrine cells restricted in distribution to the dorsal retina. Visual Neuroscience. 14: 601-8. PMID 9194326 DOI: 10.1017/S0952523800012256 |
0.461 |
|
| 1997 |
Flannery JG, Zolotukhin S, Vaquero MI, LaVail MM, Muzyczka N, Hauswirth WW. Efficient photoreceptor-targeted gene expression in vivo by recombinant adeno-associated virus. Proceedings of the National Academy of Sciences of the United States of America. 94: 6916-21. PMID 9192666 DOI: 10.1073/pnas.94.13.6916 |
0.548 |
|
| 1997 |
Hauswirth WW, Guy JF, Flannery JG. Efficient photoreceptor-targeted gene expression in vivo mediated by recombinant adeno-associated virus Investigative Ophthalmology and Visual Science. 38: S258. |
0.322 |
|
| 1996 |
Chen J, Flannery JG, LaVail MM, Steinberg RH, Xu J, Simon MI. bcl-2 overexpression reduces apoptotic photoreceptor cell death in three different retinal degenerations. Proceedings of the National Academy of Sciences of the United States of America. 93: 7042-7. PMID 8692941 DOI: 10.1073/Pnas.93.14.7042 |
0.526 |
|
| 1996 |
Adamus G, Aptsiauri N, Guy J, Heckenlively J, Flannery J, Hargrave PA. The occurrence of serum autoantibodies against enolase in cancer-associated retinopathy Clinical Immunology and Immunopathology. 78: 120-129. PMID 8625554 DOI: 10.1006/clin.1996.0021 |
0.343 |
|
| 1996 |
Milam AH, Flannery JG, Possin DE, Huang J, Saari JC. ALDH-positive amacrine cells in the dorsal retina Investigative Ophthalmology and Visual Science. 37: S633. |
0.359 |
|
| 1996 |
Steinberg RH, Flannery JG, Naash M, Oh P, Matthes MT, Yasumura D, Lau-Villacorta C, Chen J, LaVail MM. Transgenic rat models of inherited retinal degeneration caused by mutant opsin genes Investigative Ophthalmology and Visual Science. 37: S698. |
0.454 |
|
| 1994 |
Farber DB, Flannery JG, Bowes-Rickman C. The rd mouse story: Seventy years of research on an animal model of inherited retinal degeneration Progress in Retinal and Eye Research. 13: 31-64. DOI: 10.1016/1350-9462(94)90004-3 |
0.493 |
|
| 1993 |
Flannery JG, Dinehart WJ, Street C, Hauswirth WW. In Situ Hybridization of Retinal Messenger RNA Using Nonradioactive Synthetic Probes Methods in Neurosciences. 15: 357-376. DOI: 10.1016/B978-0-12-185279-5.50032-7 |
0.443 |
|
| 1993 |
Adamus G, Anderson DH, Bok D, BuczYłko J, Cook NJ, Crabb J, DeCaluwé LLJ, DeGrip WJ, Deretic D, Dinehart WJ, Donoso LA, Erickson PA, Fisher SK, Flannery JG, Fliesler SJ, et al. Contributors to Volume 15 Methods in Neurosciences. 15. DOI: 10.1016/B978-0-12-185279-5.50004-2 |
0.437 |
|
| 1992 |
Michels M, Flannery JG, Lewis H. Noncontact transscleral neodymium-YAG laser photocoagulation of the pigmented rabbit retina. Archives of Ophthalmology (Chicago, Ill. : 1960). 110: 395-8. PMID 1543460 DOI: 10.1001/archopht.1992.01080150093035 |
0.449 |
|
| 1992 |
Lem J, Flannery JG, Li T, Applebury ML, Farber DB, Simon MI. Retinal degeneration is rescued in transgenic rd mice by expression of the cGMP phosphodiesterase beta subunit. Proceedings of the National Academy of Sciences of the United States of America. 89: 4422-6. PMID 1350091 DOI: 10.1073/Pnas.89.10.4422 |
0.533 |
|
| 1991 |
Lewis H, Resnick SC, Flannery JG, Straatsma BR. Tissue plasminogen activator treatment of experimental subretinal hemorrhage. American Journal of Ophthalmology. 111: 197-204. PMID 1899537 DOI: 10.1016/S0002-9394(14)72259-7 |
0.366 |
|
| 1991 |
Lem J, Applebury ML, Falk JD, Flannery JG, Simon MI. Tissue-specific and developmental regulation of rod opsin chimeric genes in transgenic mice. Neuron. 6: 201-10. PMID 1825171 DOI: 10.1016/0896-6273(91)90356-5 |
0.433 |
|
| 1990 |
Flannery JG, Bird AC, Farber DB, Weleber RG, Bok D. A histopathologic study of a choroideremia carrier. Investigative Ophthalmology & Visual Science. 31: 229-36. PMID 2303326 |
0.433 |
|
| 1990 |
Flannery JG, O'Day W, Pfeffer BA, Horwitz J, Bok D. Uptake, processing and release of retinoids by cultured human retinal pigment epithelium. Experimental Eye Research. 51: 717-28. PMID 2265683 DOI: 10.1016/0014-4835(90)90057-2 |
0.481 |
|
| 1989 |
Flannery JG, Farber DB, Bird AC, Bok D. Degenerative changes in a retina affected with autosomal dominant retinitis pigmentosa. Investigative Ophthalmology & Visual Science. 30: 191-211. PMID 2914751 |
0.491 |
|
| 1987 |
Farber DB, Flannery JG, Bird AC, Shuster T, Bok D. Histopathological and biochemical studies on donor eyes affected with retinitis pigmentosa. Progress in Clinical and Biological Research. 247: 53-67. PMID 2825216 |
0.388 |
|
| 1985 |
Farber DB, Flannery JG, Lolley RN, Bok D. Distribution patterns of photoreceptors, protein, and cyclic nucleotides in the human retina. Investigative Ophthalmology & Visual Science. 26: 1558-68. PMID 2997074 |
0.346 |
|
| 1984 |
Flannery JG, Fisher SK. Circadian disc shedding in Xenopus retina in vitro. Investigative Ophthalmology & Visual Science. 25: 229-32. PMID 6321387 |
0.484 |
|
| 1979 |
Flannery JG, Fisher SK. Light-triggered rod disc shedding in Xenopus retina in vitro. Investigative Ophthalmology & Visual Science. 18: 638-42. PMID 447463 |
0.55 |
|
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