| Year |
Citation |
Score |
| 2020 |
Joshi CR, Stacy S, Sumien N, Ghorpade A, Borgmann K. Astrocyte HIV-1 Tat Differentially Modulates Behavior and Brain MMP/TIMP Balance During Short and Prolonged Induction in Transgenic Mice. Frontiers in Neurology. 11: 593188. PMID 33384653 DOI: 10.3389/fneur.2020.593188 |
0.406 |
|
| 2020 |
Swanta N, Aryal S, Nejtek V, Shenoy S, Ghorpade A, Borgmann K. Blood-based inflammation biomarkers of neurocognitive impairment in people living with HIV. Journal of Neurovirology. PMID 32193795 DOI: 10.1007/s13365-020-00834-3 |
0.339 |
|
| 2020 |
Edara VV, Ghorpade A, Borgmann K. Insights into the gene expression profiles of active and restricted R/G-HIV+ human astrocytes: Implications for shock or lock therapies in the brain. Journal of Virology. PMID 31896591 DOI: 10.1128/JVI.01563-19 |
0.496 |
|
| 2018 |
Nooka S, Ghorpade A. Organellar stress intersects the astrocyte endoplasmic reticulum, mitochondria and nucleolus in HIV associated neurodegeneration. Cell Death & Disease. 9: 317. PMID 29472528 DOI: 10.1038/s41419-018-0341-3 |
0.357 |
|
| 2018 |
Bowen KE, Mathew SO, Borgmann K, Ghorpade A, Mathew PA. A novel ligand on astrocytes interacts with natural cytotoxicity receptor NKp44 regulating immune response mediated by NK cells. Plos One. 13: e0193008. PMID 29447242 DOI: 10.1371/Journal.Pone.0193008 |
0.362 |
|
| 2017 |
Nooka S, Ghorpade A. HIV-1-associated inflammation and antiretroviral therapy regulate astrocyte endoplasmic reticulum stress responses. Cell Death Discovery. 3: 17061. PMID 29354290 DOI: 10.1038/cddiscovery.2017.61 |
0.365 |
|
| 2017 |
Borgmann K, Ghorpade A. Methamphetamine Augments Concurrent Astrocyte Mitochondrial Stress, Oxidative Burden, and Antioxidant Capacity: Tipping the Balance in HIV-Associated Neurodegeneration. Neurotoxicity Research. PMID 28993979 DOI: 10.1007/s12640-017-9812-z |
0.341 |
|
| 2016 |
Vartak-Sharma N, Nooka S, Ghorpade A. Astrocyte Elevated Gene-1 (AEG-1) and the A(E)Ging HIV/AIDS-HAND. Progress in Neurobiology. PMID 27090750 DOI: 10.1016/j.pneurobio.2016.03.006 |
0.439 |
|
| 2015 |
Pandey R, Ghorpade A. Cytosolic phospholipase A2 regulates alcohol-mediated astrocyte inflammatory responses in HIV-associated neurocognitive disorders. Cell Death Discovery. 1: 15045. PMID 27551474 DOI: 10.1038/cddiscovery.2015.45 |
0.43 |
|
| 2015 |
Borgmann K, Ghorpade A. HIV-1, methamphetamine and astrocytes at neuroinflammatory Crossroads. Frontiers in Microbiology. 6: 1143. PMID 26579077 DOI: 10.3389/fmicb.2015.01143 |
0.515 |
|
| 2015 |
Mamik MK, Ghorpade A. CXCL8 as a Potential Therapeutic Target for HIV-Associated Neurocognitive Disorders. Current Drug Targets. PMID 26112047 |
0.528 |
|
| 2014 |
Cisneros IE, Ghorpade A. Methamphetamine and HIV-1-induced neurotoxicity: role of trace amine associated receptor 1 cAMP signaling in astrocytes. Neuropharmacology. 85: 499-507. PMID 24950453 DOI: 10.1016/J.Neuropharm.2014.06.011 |
0.462 |
|
| 2014 |
Vartak-Sharma N, Gelman BB, Joshi C, Borgamann K, Ghorpade A. Astrocyte elevated gene-1 is a novel modulator of HIV-1-associated neuroinflammation via regulation of nuclear factor-κB signaling and excitatory amino acid transporter-2 repression. The Journal of Biological Chemistry. 289: 19599-612. PMID 24855648 DOI: 10.1074/Jbc.M114.567644 |
0.493 |
|
| 2014 |
Mamik MK, Ghorpade A. Chemokine CXCL8 promotes HIV-1 replication in human monocyte-derived macrophages and primary microglia via nuclear factor-κB pathway. Plos One. 9: e92145. PMID 24662979 DOI: 10.1371/journal.pone.0092145 |
0.522 |
|
| 2012 |
Mamik MK, Ghorpade A. Src homology-2 domain-containing protein tyrosine phosphatase (SHP) 2 and p38 regulate the expression of chemokine CXCL8 in human astrocytes. Plos One. 7: e45596. PMID 23029125 DOI: 10.1371/journal.pone.0045596 |
0.326 |
|
| 2012 |
Ashutosh, Chao C, Borgmann K, Brew K, Ghorpade A. Tissue inhibitor of metalloproteinases-1 protects human neurons from staurosporine and HIV-1-induced apoptosis: mechanisms and relevance to HIV-1-associated dementia. Cell Death & Disease. 3: e332. PMID 22739984 DOI: 10.1038/cddis.2012.54 |
0.642 |
|
| 2012 |
Cisneros IE, Ghorpade A. HIV-1, methamphetamine and astrocyte glutamate regulation: combined excitotoxic implications for neuro-AIDS. Current Hiv Research. 10: 392-406. PMID 22591363 DOI: 10.2174/157016212802138832 |
0.44 |
|
| 2011 |
Mamik MK, Banerjee S, Walseth TF, Hirte R, Tang L, Borgmann K, Ghorpade A. HIV-1 and IL-1β regulate astrocytic CD38 through mitogen-activated protein kinases and nuclear factor-κB signaling mechanisms. Journal of Neuroinflammation. 8: 145. PMID 22027397 DOI: 10.1186/1742-2094-8-145 |
0.807 |
|
| 2011 |
Ashutosh, Kou W, Cotter R, Borgmann K, Wu L, Persidsky R, Sakhuja N, Ghorpade A. CXCL8 protects human neurons from amyloid-β-induced neurotoxicity: relevance to Alzheimer's disease. Biochemical and Biophysical Research Communications. 412: 565-71. PMID 21840299 DOI: 10.1016/J.Bbrc.2011.07.127 |
0.754 |
|
| 2011 |
Fields J, Gardner-Mercer J, Borgmann K, Clark I, Ghorpade A. CCAAT/enhancer binding protein β expression is increased in the brain during HIV-1-infection and contributes to regulation of astrocyte tissue inhibitor of metalloproteinase-1. Journal of Neurochemistry. 118: 93-104. PMID 21281310 DOI: 10.1111/j.1471-4159.2011.07203.x |
0.489 |
|
| 2011 |
Borgmann K, Rao KS, Labhasetwar V, Ghorpade A. Efficacy of Tat-conjugated ritonavir-loaded nanoparticles in reducing HIV-1 replication in monocyte-derived macrophages and cytocompatibility with macrophages and human neurons. Aids Research and Human Retroviruses. 27: 853-62. PMID 21175357 DOI: 10.1089/Aid.2010.0295 |
0.582 |
|
| 2010 |
Jing T, Wu L, Borgmann K, Surendran S, Ghorpade A, Liu J, Xiong H. Soluble factors from IL-1β-stimulated astrocytes activate NR1a/NR2B receptors: implications for HIV-1-induced neurodegeneration. Biochemical and Biophysical Research Communications. 402: 241-6. PMID 20933498 DOI: 10.1016/j.bbrc.2010.10.006 |
0.408 |
|
| 2010 |
Xie L, Poteet EC, Li W, Scott AE, Liu R, Wen Y, Ghorpade A, Simpkins JW, Yang SH. Modulation of polymorphonuclear neutrophil functions by astrocytes. Journal of Neuroinflammation. 7: 53. PMID 20828397 DOI: 10.1186/1742-2094-7-53 |
0.399 |
|
| 2009 |
Chao C, Ghorpade A. Production and Roles of Glial Tissue Inhibitor of Metalloproteinases-1 in Human Immunodeficiency Virus-1-Associated Dementia Neuroinflammation: A Review. American Journal of Infectious Diseases. 5: 314-320. PMID 20585405 DOI: 10.3844/ajidsp.2009.314.319 |
0.569 |
|
| 2009 |
Rao KS, Ghorpade A, Labhasetwar V. Targeting anti-HIV drugs to the CNS. Expert Opinion On Drug Delivery. 6: 771-84. PMID 19566446 DOI: 10.1517/17425240903081705 |
0.435 |
|
| 2009 |
Kou W, Banerjee S, Eudy J, Smith LM, Persidsky R, Borgmann K, Wu L, Sakhuja N, Deshpande MS, Walseth TF, Ghorpade A. CD38 regulation in activated astrocytes: implications for neuroinflammation and HIV-1 brain infection. Journal of Neuroscience Research. 87: 2326-39. PMID 19365854 DOI: 10.1002/Jnr.22060 |
0.814 |
|
| 2008 |
Banerjee S, Walseth TF, Borgmann K, Wu L, Bidasee KR, Kannan MS, Ghorpade A. CD38/cyclic ADP-ribose regulates astrocyte calcium signaling: implications for neuroinflammation and HIV-1-associated dementia. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 3: 154-64. PMID 18581239 DOI: 10.1007/S11481-008-9105-7 |
0.785 |
|
| 2008 |
Ghorpade A, Gendelman HE, Kipnis J. Macrophages, microglia, and dendritic C Neuroimmune Pharmacology. 89-104. DOI: 10.1007/978-0-387-72573-4_9 |
0.529 |
|
| 2006 |
Vitvitsky V, Thomas M, Ghorpade A, Gendelman HE, Banerjee R. A functional transsulfuration pathway in the brain links to glutathione homeostasis. The Journal of Biological Chemistry. 281: 35785-93. PMID 17005561 DOI: 10.1074/Jbc.M602799200 |
0.616 |
|
| 2006 |
Peng H, Erdmann N, Whitney N, Dou H, Gorantla S, Gendelman HE, Ghorpade A, Zheng J. HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta. Glia. 54: 619-29. PMID 16944452 DOI: 10.1002/Glia.20409 |
0.788 |
|
| 2006 |
Potula R, Haorah J, Knipe B, Leibhart J, Chrastil J, Heilman D, Dou H, Reddy R, Ghorpade A, Persidsky Y. Alcohol abuse enhances neuroinflammation and impairs immune responses in an animal model of human immunodeficiency virus-1 encephalitis. The American Journal of Pathology. 168: 1335-44. PMID 16565506 DOI: 10.2353/Ajpath.2006.051181 |
0.682 |
|
| 2006 |
Gardner J, Borgmann K, Deshpande MS, Dhar A, Wu L, Persidsky R, Ghorpade A. Potential mechanisms for astrocyte-TIMP-1 downregulation in chronic inflammatory diseases. Journal of Neuroscience Research. 83: 1281-92. PMID 16555295 DOI: 10.1002/Jnr.20823 |
0.575 |
|
| 2006 |
Dhar A, Gardner J, Borgmann K, Wu L, Ghorpade A. Novel role of TGF-beta in differential astrocyte-TIMP-1 regulation: implications for HIV-1-dementia and neuroinflammation. Journal of Neuroscience Research. 83: 1271-80. PMID 16496359 DOI: 10.1002/Jnr.20787 |
0.509 |
|
| 2005 |
Haorah J, Knipe B, Leibhart J, Ghorpade A, Persidsky Y. Alcohol-induced oxidative stress in brain endothelial cells causes blood-brain barrier dysfunction. Journal of Leukocyte Biology. 78: 1223-32. PMID 16204625 DOI: 10.1189/Jlb.0605340 |
0.519 |
|
| 2005 |
Borgmann K, Gendelman HE, Ghorpade A. Isolation and HIV-1 infection of primary human microglia from fetal and adult tissue. Methods in Molecular Biology (Clifton, N.J.). 304: 49-70. PMID 16061966 DOI: 10.1385/1-59259-907-9:049 |
0.751 |
|
| 2005 |
Haorah J, Heilman D, Knipe B, Chrastil J, Leibhart J, Ghorpade A, Miller DW, Persidsky Y. Ethanol-induced activation of myosin light chain kinase leads to dysfunction of tight junctions and blood-brain barrier compromise. Alcoholism, Clinical and Experimental Research. 29: 999-1009. PMID 15976526 DOI: 10.1097/01.Alc.0000166944.79914.0A |
0.59 |
|
| 2005 |
Deshpande M, Zheng J, Borgmann K, Persidsky R, Wu L, Schellpeper C, Ghorpade A. Role of activated astrocytes in neuronal damage: potential links to HIV-1-associated dementia. Neurotoxicity Research. 7: 183-92. PMID 15897153 DOI: 10.1007/Bf03036448 |
0.692 |
|
| 2005 |
Ghorpade A, Bruch L, Persidsky Y, Chin B, Brown WH, Borgmann K, Persidsky R, Wu L, Holter S, Cotter R, Faraci J, Heilman D, Meyer V, Potter JF, Swindells S, et al. Development of a rapid autopsy program for studies of brain immunity. Journal of Neuroimmunology. 163: 135-44. PMID 15885316 DOI: 10.1016/J.Jneuroim.2005.01.021 |
0.749 |
|
| 2005 |
Ghorpade A, Persidsky Y, Swindells S, Borgmann K, Persidsky R, Holter S, Cotter R, Gendelman HE. Neuroinflammatory responses from microglia recovered from HIV-1-infected and seronegative subjects. Journal of Neuroimmunology. 163: 145-56. PMID 15869805 DOI: 10.1016/J.Jneuroim.2005.01.022 |
0.827 |
|
| 2004 |
Haorah J, Heilman D, Diekmann C, Osna N, Donohue TM, Ghorpade A, Persidsky Y. Alcohol and HIV decrease proteasome and immunoproteasome function in macrophages: implications for impaired immune function during disease. Cellular Immunology. 229: 139-48. PMID 15474528 DOI: 10.1016/J.Cellimm.2004.07.005 |
0.727 |
|
| 2004 |
Nukuna A, Gendelman HE, Limoges J, Rasmussen J, Poluektova L, Ghorpade A, Persidsky Y. Levels of human immunodeficiency virus type 1 (HIV-1) replication in macrophages determines the severity of murine HIV-1 encephalitis. Journal of Neurovirology. 10: 82-90. PMID 14982744 DOI: 10.1080/753312757 |
0.799 |
|
| 2003 |
Gardner J, Ghorpade A. Tissue inhibitor of metalloproteinase (TIMP)-1: the TIMPed balance of matrix metalloproteinases in the central nervous system. Journal of Neuroscience Research. 74: 801-6. PMID 14648584 DOI: 10.1002/Jnr.10835 |
0.53 |
|
| 2003 |
Ghorpade A, Holter S, Borgmann K, Persidsky R, Wu L. HIV-1 and IL-1 beta regulate Fas ligand expression in human astrocytes through the NF-kappa B pathway. Journal of Neuroimmunology. 141: 141-9. PMID 12965265 DOI: 10.1016/S0165-5728(03)00222-4 |
0.525 |
|
| 2003 |
Suryadevara R, Holter S, Borgmann K, Persidsky R, Labenz-Zink C, Persidsky Y, Gendelman HE, Wu L, Ghorpade A. Regulation of tissue inhibitor of metalloproteinase-1 by astrocytes: links to HIV-1 dementia. Glia. 44: 47-56. PMID 12951656 DOI: 10.1002/Glia.10266 |
0.783 |
|
| 2003 |
Wang Z, Pekarskaya O, Bencheikh M, Chao W, Gelbard HA, Ghorpade A, Rothstein JD, Volsky DJ. Reduced expression of glutamate transporter EAAT2 and impaired glutamate transport in human primary astrocytes exposed to HIV-1 or gp120. Virology. 312: 60-73. PMID 12890621 DOI: 10.1016/S0042-6822(03)00181-8 |
0.467 |
|
| 2003 |
Erichsen D, Lopez AL, Peng H, Niemann D, Williams C, Bauer M, Morgello S, Cotter RL, Ryan LA, Ghorpade A, Gendelman HE, Zheng J. Neuronal injury regulates fractalkine: relevance for HIV-1 associated dementia. Journal of Neuroimmunology. 138: 144-55. PMID 12742664 DOI: 10.1016/S0165-5728(03)00117-6 |
0.822 |
|
| 2003 |
Ikezu T, Luo X, Weber GA, Zhao J, McCabe L, Buescher JL, Ghorpade A, Zheng J, Xiong H. Amyloid precursor protein-processing products affect mononuclear phagocyte activation: pathways for sAPP- and Abeta-mediated neurotoxicity. Journal of Neurochemistry. 85: 925-34. PMID 12716424 DOI: 10.1046/J.1471-4159.2003.01739.X |
0.59 |
|
| 2003 |
Xiong H, Boyle J, Winkelbauer M, Gorantla S, Zheng J, Ghorpade A, Persidsky Y, Carlson KA, Gendelman HE. Inhibition of long-term potentiation by interleukin-8: implications for human immunodeficiency virus-1-associated dementia. Journal of Neuroscience Research. 71: 600-7. PMID 12548717 DOI: 10.1002/Jnr.10503 |
0.777 |
|
| 2003 |
Ghorpade A, Gendelman HE. Non-neuronal interactions in HIV-1-associated dementia Advances in Molecular and Cell Biology. 31: 901-920. DOI: 10.1016/S1569-2558(03)31040-9 |
0.763 |
|
| 2001 |
Zheng J, Thylin MR, Persidsky Y, Williams CE, Cotter RL, Zink W, Ryan L, Ghorpade A, Lewis K, Gendelman HE. HIV-1 infected immune competent mononuclear phagocytes influence the pathways to neuronal demise. Neurotoxicity Research. 3: 461-84. PMID 14715459 DOI: 10.1007/Bf03033204 |
0.789 |
|
| 2001 |
Zheng J, Thylin MR, Cotter RL, Lopez AL, Ghorpade A, Persidsky Y, Xiong H, Leisman GB, Che MH, Gendelman HE. HIV-1 infected and immune competent mononuclear phagocytes induce quantitative alterations in neuronal dendritic arbor: relevance for HIV-1-associated dementia. Neurotoxicity Research. 3: 443-59. PMID 14715458 DOI: 10.1007/Bf03033203 |
0.83 |
|
| 2001 |
Canki M, Thai JN, Chao W, Ghorpade A, Potash MJ, Volsky DJ. Highly productive infection with pseudotyped human immunodeficiency virus type 1 (HIV-1) indicates no intracellular restrictions to HIV-1 replication in primary human astrocytes. Journal of Virology. 75: 7925-33. PMID 11483737 DOI: 10.1128/Jvi.75.17.7925-7933.2001 |
0.57 |
|
| 2001 |
Ghorpade A, Persidskaia R, Suryadevara R, Che M, Liu XJ, Persidsky Y, Gendelman HE. Mononuclear phagocyte differentiation, activation, and viral infection regulate matrix metalloproteinase expression: implications for human immunodeficiency virus type 1-associated dementia. Journal of Virology. 75: 6572-83. PMID 11413325 DOI: 10.1128/Jvi.75.14.6572-6583.2001 |
0.75 |
|
| 1999 |
Persidsky Y, Ghorpade A, Rasmussen J, Limoges J, Liu XJ, Stins M, Fiala M, Way D, Kim KS, Witte MH, Weinand M, Carhart L, Gendelman HE. Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1 encephalitis. The American Journal of Pathology. 155: 1599-611. PMID 10550317 DOI: 10.1016/S0002-9440(10)65476-4 |
0.788 |
|
| 1999 |
Zheng J, Ghorpade A, Niemann D, Cotter RL, Thylin MR, Epstein L, Swartz JM, Shepard RB, Liu X, Nukuna A, Gendelman HE. Lymphotropic virions affect chemokine receptor-mediated neural signaling and apoptosis: implications for human immunodeficiency virus type 1-associated dementia. Journal of Virology. 73: 8256-67. PMID 10482576 DOI: 10.1128/Jvi.73.10.8256-8267.1999 |
0.829 |
|
| 1999 |
Zheng J, Thylin MR, Ghorpade A, Xiong H, Persidsky Y, Cotter R, Niemann D, Che M, Zeng YC, Gelbard HA, Shepard RB, Swartz JM, Gendelman HE. Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia. Journal of Neuroimmunology. 98: 185-200. PMID 10430052 DOI: 10.1016/S0165-5728(99)00049-1 |
0.82 |
|
| 1998 |
Gendelman HE, Zheng J, Coulter CL, Ghorpade A, Che M, Thylin M, Rubocki R, Persidsky Y, Hahn F, Reinhard J, Swindells S. Suppression of inflammatory neurotoxins by highly active antiretroviral therapy in human immunodeficiency virus-associated dementia. The Journal of Infectious Diseases. 178: 1000-7. PMID 9806027 DOI: 10.1086/515693 |
0.781 |
|
| 1998 |
Davis V, Persidskaia R, Baca-Regen L, Itoh Y, Nagase H, Persidsky Y, Ghorpade A, Baxter BT. Matrix metalloproteinase-2 production and its binding to the matrix are increased in abdominal aortic aneurysms. Arteriosclerosis, Thrombosis, and Vascular Biology. 18: 1625-33. PMID 9763536 DOI: 10.1161/01.Atv.18.10.1625 |
0.547 |
|
| 1998 |
Ghorpade A, Xia MQ, Hyman BT, Persidsky Y, Nukuna A, Bock P, Che M, Limoges J, Gendelman HE, Mackay CR. Role of the beta-chemokine receptors CCR3 and CCR5 in human immunodeficiency virus type 1 infection of monocytes and microglia. Journal of Virology. 72: 3351-61. PMID 9525662 DOI: 10.1128/Jvi.72.4.3351-3361.1998 |
0.802 |
|
| 1998 |
Ghorpade A, Nukuna A, Che M, Haggerty S, Persidsky Y, Carter E, Carhart L, Shafer L, Gendelman HE. Human immunodeficiency virus neurotropism: an analysis of viral replication and cytopathicity for divergent strains in monocytes and microglia. Journal of Virology. 72: 3340-50. PMID 9525661 DOI: 10.1128/Jvi.72.4.3340-3350.1998 |
0.801 |
|
| 1997 |
Gendelman HE, Persidsky Y, Ghorpade A, Limoges J, Stins M, Fiala M, Morrisett R. The neuropathogenesis of the AIDS dementia complex. Aids (London, England). 11: S35-45. PMID 9451964 |
0.65 |
|
| 1997 |
Gendelman HE, Zheng J, Ghorpade A, Rubocki R, Persidsky Y, Coulter C, Hahn FJ, Swindells S. HIV-1 dementia: A metabolic encephalopathy abrogated by highly active antiretroviral therapy (HAART) Clinical Infectious Diseases. 25: 457. |
0.634 |
|
| 1996 |
Bukrinskaya AG, Ghorpade A, Heinzinger NK, Smithgall TE, Lewis RE, Stevenson M. Phosphorylation-dependent human immunodeficiency virus type 1 infection and nuclear targeting of viral DNA. Proceedings of the National Academy of Sciences of the United States of America. 93: 367-71. PMID 8552640 DOI: 10.1073/Pnas.93.1.367 |
0.427 |
|
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