Robert G. Korneluk - Publications

Affiliations: 
University of Ottawa, Ottawa, ON, Canada 
Area:
Microbiology Biology, Molecular Biology, Cell Biology

113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Beug ST, Korneluk RG, LaCasse EC. Sp3-cificity of TNF-α expression promotes the Smac mimetic-mediated killing of cancer cells. Molecular & Cellular Oncology. 6: 1607456. PMID 31211235 DOI: 10.1080/23723556.2019.1607456  0.321
2019 Lala-Tabbert N, Lejmi-Mrad R, Timusk K, Fukano M, Holbrook J, St-Jean M, LaCasse EC, Korneluk RG. Targeted ablation of the cellular inhibitor of apoptosis 1 (cIAP1) attenuates denervation-induced skeletal muscle atrophy. Skeletal Muscle. 9: 13. PMID 31126323 DOI: 10.1186/S13395-019-0201-6  0.337
2019 Beug ST, Cheung HH, Sanda T, St-Jean M, Beauregard CE, Mamady H, Baird SD, LaCasse EC, Korneluk RG. The transcription factor SP3 drives TNF-α expression in response to Smac mimetics. Science Signaling. 12. PMID 30696705 DOI: 10.1126/Scisignal.Aat9563  0.305
2018 Beug ST, Pichette SJ, St-Jean M, Holbrook J, Walker DE, LaCasse EC, Korneluk RG. Combination of IAP Antagonists and TNF-α-Armed Oncolytic Viruses Induce Tumor Vascular Shutdown and Tumor Regression. Molecular Therapy Oncolytics. 10: 28-39. PMID 30101187 DOI: 10.1016/J.Omto.2018.06.002  0.308
2018 Rijal D, Ariana A, Wight A, Kim K, Alturki NA, Aamir Z, Ametepe E, Korneluk RG, Tiedje C, Menon MB, Gaestel M, McComb S, Sad S. Differentiated Macrophages Acquire a Pro-Inflammatory and Cell Death-Resistant Phenotype Due to Increasing XIAP and P38-mediated inhibition of RipK1. The Journal of Biological Chemistry. PMID 29899110 DOI: 10.1074/Jbc.Ra118.003614  0.393
2018 Alturki NA, McComb S, Ariana A, Rijal D, Korneluk RG, Sun SC, Alnemri E, Sad S. Triad3a induces the degradation of early necrosome to limit RipK1-dependent cytokine production and necroptosis. Cell Death & Disease. 9: 592. PMID 29789521 DOI: 10.1038/S41419-018-0672-0  0.33
2017 Beug ST, Beauregard CE, Healy C, Sanda T, St-Jean M, Chabot J, Walker DE, Mohan A, Earl N, Lun X, Senger DL, Robbins SM, Staeheli P, Forsyth PA, Alain T, ... ... Korneluk RG, et al. Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma. Nature Communications. 8. PMID 28198370 DOI: 10.1038/Ncomms14278  0.326
2016 Dobson CC, Naing T, Beug ST, Faye MD, Chabot J, St-Jean M, Walker DE, LaCasse EC, Stojdl DF, Korneluk RG, Holcik M. Oncolytic virus synergizes with Smac mimetic compounds to induce rhabdomyosarcoma cell death in a syngeneic murine model. Oncotarget. PMID 27966453 DOI: 10.18632/Oncotarget.13849  0.358
2016 LaCasse E, Beug S, Healey C, Beauregard C, Sanda T, Alain T, Korneluk R. Abstract B034: Smac mimetics synergistically improve the efficacy of cancer immunotherapies including immune checkpoint blockade in preclinical models Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-B034  0.32
2015 Beug ST, Conrad DP, Alain T, Korneluk RG, Lacasse EC. Combinatorial cancer immunotherapy strategies with proapoptotic small-molecule IAP antagonists. The International Journal of Developmental Biology. 59: 141-7. PMID 26374535 DOI: 10.1387/Ijdb.150084El  0.344
2015 Faye MD, Beug ST, Graber TE, Earl N, Xiang X, Wild B, Langlois S, Michaud J, Cowan KN, Korneluk RG, Holcik M. IGF2BP1 controls cell death and drug resistance in rhabdomyosarcomas by regulating translation of cIAP1. Oncogene. 34: 1532-41. PMID 24704827 DOI: 10.1038/Onc.2014.90  0.383
2015 Korneluk RG. ID: 261: Smac mimetics combined with innate immune stimuli: new tools to kill tumor cells Cytokine. 76: 61. DOI: 10.1016/J.Cyto.2015.08.022  0.326
2014 Enwere EK, Lacasse EC, Adam NJ, Korneluk RG. Role of the TWEAK-Fn14-cIAP1-NF-κB Signaling Axis in the Regulation of Myogenesis and Muscle Homeostasis. Frontiers in Immunology. 5: 34. PMID 24550918 DOI: 10.3389/Fimmu.2014.00034  0.36
2014 Beug ST, Tang VA, LaCasse EC, Cheung HH, Beauregard CE, Brun J, Nuyens JP, Earl N, St-Jean M, Holbrook J, Dastidar H, Mahoney DJ, Ilkow C, Le Boeuf F, Bell JC, ... Korneluk RG, et al. Smac mimetics and innate immune stimuli synergize to promote tumor death. Nature Biotechnology. 32: 182-90. PMID 24463573 DOI: 10.1038/Nbt.2806  0.345
2014 Faye MD, Graber TE, Beug S, Xiang X, Wild B, Langlois S, Cowan KN, Korneluk RG, Holcik M. Abstract 4256: Characterization of the cellular inhibitor of apoptosis 1 (cIAP1) IRES trans-acting factors and their contribution to apoptotic resistance in rhabdomyosarcomas Cancer Research. 74: 4256-4256. DOI: 10.1158/1538-7445.Am2014-4256  0.391
2013 Enwere EK, Boudreault L, Holbrook J, Timusk K, Earl N, LaCasse E, Renaud JM, Korneluk RG. Loss of cIAP1 attenuates soleus muscle pathology and improves diaphragm function in mdx mice. Human Molecular Genetics. 22: 867-78. PMID 23184147 DOI: 10.1093/Hmg/Dds493  0.352
2013 Beug ST, Tang VA, Cheung HC, Boeuf FL, Bell JC, LaCasse EC, Korneluk RG. 21: Interferon-mediated potentiation of SMAC mimetic compound cytotoxicity by oncolytic virotherapy Cytokine. 63: 248. DOI: 10.1016/J.Cyto.2013.06.024  0.348
2012 Enwere EK, Holbrook J, Lejmi-Mrad R, Vineham J, Timusk K, Sivaraj B, Isaac M, Uehling D, Al-awar R, LaCasse E, Korneluk RG. TWEAK and cIAP1 regulate myoblast fusion through the noncanonical NF-κB signaling pathway. Science Signaling. 5: ra75. PMID 23074266 DOI: 10.1126/Scisignal.2003086  0.348
2012 Beug ST, Cheung HH, LaCasse EC, Korneluk RG. Modulation of immune signalling by inhibitors of apoptosis. Trends in Immunology. 33: 535-45. PMID 22836014 DOI: 10.1016/J.It.2012.06.004  0.356
2012 McComb S, Cheung HH, Korneluk RG, Wang S, Krishnan L, Sad S. cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation. Cell Death and Differentiation. 19: 1791-801. PMID 22576661 DOI: 10.1038/Cdd.2012.59  0.391
2011 Cheung HH, St Jean M, Beug ST, Lejmi-Mrad R, LaCasse E, Baird SD, Stojdl DF, Screaton RA, Korneluk RG. SMG1 and NIK regulate apoptosis induced by Smac mimetic compounds. Cell Death & Disease. 2: e146. PMID 21490678 DOI: 10.1038/Cddis.2011.25  0.39
2010 Cheung HH, Beug ST, St Jean M, Brewster A, Kelly NL, Wang S, Korneluk RG. Smac mimetic compounds potentiate interleukin-1beta-mediated cell death. The Journal of Biological Chemistry. 285: 40612-23. PMID 20956527 DOI: 10.1074/Jbc.M110.183616  0.313
2010 Wang J, Menchenton T, Yin S, Yu Z, Bance M, Morris DP, Moore CS, Korneluk RG, Robertson GS. Over-expression of X-linked inhibitor of apoptosis protein slows presbycusis in C57BL/6J mice. Neurobiology of Aging. 31: 1238-49. PMID 18755525 DOI: 10.1016/J.Neurobiolaging.2008.07.016  0.346
2009 Cheung HH, Mahoney DJ, Lacasse EC, Korneluk RG. Down-regulation of c-FLIP Enhances death of cancer cells by smac mimetic compound. Cancer Research. 69: 7729-38. PMID 19773432 DOI: 10.1158/0008-5472.Can-09-1794  0.348
2009 Bertrand MJ, Doiron K, Labbé K, Korneluk RG, Barker PA, Saleh M. Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2. Immunity. 30: 789-801. PMID 19464198 DOI: 10.1016/J.Immuni.2009.04.011  0.326
2009 Tu SP, Liston P, Cui JT, Lin MC, Jiang XH, Yang Y, Gu Q, Jiang SH, Lum CT, Kung HF, Korneluk RG, Wong BC. Restoration of XAF1 expression induces apoptosis and inhibits tumor growth in gastric cancer. International Journal of Cancer. 125: 688-97. PMID 19358264 DOI: 10.1002/Ijc.24282  0.352
2008 Zarnegar BJ, Wang Y, Mahoney DJ, Dempsey PW, Cheung HH, He J, Shiba T, Yang X, Yeh WC, Mak TW, Korneluk RG, Cheng G. Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK. Nature Immunology. 9: 1371-8. PMID 18997794 DOI: 10.1038/Ni.1676  0.335
2008 LaCasse EC, Mahoney DJ, Cheung HH, Plenchette S, Baird S, Korneluk RG. IAP-targeted therapies for cancer. Oncogene. 27: 6252-75. PMID 18931692 DOI: 10.1038/Onc.2008.302  0.391
2008 Mahoney DJ, Cheung HH, Mrad RL, Plenchette S, Simard C, Enwere E, Arora V, Mak TW, Lacasse EC, Waring J, Korneluk RG. Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation. Proceedings of the National Academy of Sciences of the United States of America. 105: 11778-83. PMID 18697935 DOI: 10.1073/Pnas.0711122105  0.33
2008 Moore CS, Hebb AL, Blanchard MM, Crocker CE, Liston P, Korneluk RG, Robertson GS. Increased X-linked inhibitor of apoptosis protein (XIAP) expression exacerbates experimental autoimmune encephalomyelitis (EAE). Journal of Neuroimmunology. 203: 79-93. PMID 18687476 DOI: 10.1016/J.Jneuroim.2008.06.030  0.367
2008 Cheung HH, Plenchette S, Kern CJ, Mahoney DJ, Korneluk RG. The RING domain of cIAP1 mediates the degradation of RING-bearing inhibitor of apoptosis proteins by distinct pathways. Molecular Biology of the Cell. 19: 2729-40. PMID 18434593 DOI: 10.1091/Mbc.E08-01-0107  0.321
2008 Nakhaei P, Mesplède T, Sun Q, Leveillé S, Korneluk RG, Hiscott J. 10 X-linked inhibitor of apoptosis protein inhibits RIG-I signalling pathway Cytokine. 43: 239. DOI: 10.1016/J.Cyto.2008.07.050  0.327
2007 Arora V, Cheung HH, Plenchette S, Micali OC, Liston P, Korneluk RG. Degradation of survivin by the X-linked inhibitor of apoptosis (XIAP)-XAF1 complex. The Journal of Biological Chemistry. 282: 26202-9. PMID 17613533 DOI: 10.1074/Jbc.M700776200  0.405
2007 Hunter AM, LaCasse EC, Korneluk RG. The inhibitors of apoptosis (IAPs) as cancer targets. Apoptosis : An International Journal On Programmed Cell Death. 12: 1543-68. PMID 17573556 DOI: 10.1007/S10495-007-0087-3  0.372
2007 Micali OC, Cheung HH, Plenchette S, Hurley SL, Liston P, LaCasse EC, Korneluk RG. Silencing of the XAF1 gene by promoter hypermethylation in cancer cells and reactivation to TRAIL-sensitization by IFN-beta. Bmc Cancer. 7: 52. PMID 17376236 DOI: 10.1186/1471-2407-7-52  0.341
2006 Liu Z, Li H, Wu X, Yoo BH, Yan SR, Stadnyk AW, Sasazuki T, Shirasawa S, LaCasse EC, Korneluk RG, Rosen KV. Detachment-induced upregulation of XIAP and cIAP2 delays anoikis of intestinal epithelial cells. Oncogene. 25: 7680-90. PMID 16799641 DOI: 10.1038/Sj.Onc.1209753  0.396
2006 Cheung HH, LaCasse EC, Korneluk RG. X-linked inhibitor of apoptosis antagonism: strategies in cancer treatment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 3238-42. PMID 16740742 DOI: 10.1158/1078-0432.Ccr-06-0817  0.348
2006 Cheung HH, Lynn Kelly N, Liston P, Korneluk RG. Involvement of caspase-2 and caspase-9 in endoplasmic reticulum stress-induced apoptosis: a role for the IAPs. Experimental Cell Research. 312: 2347-57. PMID 16701639 DOI: 10.1016/J.Yexcr.2006.03.027  0.335
2006 Shafey D, Korneluk R, Holcik M. Distinct patterns of expression of the inhibitor of apoptosis protein cIAP2 during murine embryogenesis Apoptosis. 11: 1257-1259. PMID 16699955 DOI: 10.1007/S10495-006-6985-Y  0.36
2006 Conte D, Holcik M, Lefebvre CA, Lacasse E, Picketts DJ, Wright KE, Korneluk RG. Inhibitor of apoptosis protein cIAP2 is essential for lipopolysaccharide-induced macrophage survival. Molecular and Cellular Biology. 26: 699-708. PMID 16382159 DOI: 10.1128/Mcb.26.2.699-708.2006  0.329
2005 Emamaullee JA, Rajotte RV, Liston P, Korneluk RG, Lakey JR, Shapiro AM, Elliott JF. XIAP overexpression in human islets prevents early posttransplant apoptosis and reduces the islet mass needed to treat diabetes. Diabetes. 54: 2541-8. PMID 16123341 DOI: 10.2337/Diabetes.54.9.2541  0.342
2005 Plesner A, Liston P, Tan R, Korneluk RG, Verchere CB. The X-linked inhibitor of apoptosis protein enhances survival of murine islet allografts. Diabetes. 54: 2533-40. PMID 16123340 DOI: 10.2337/Diabetes.54.9.2533  0.341
2005 Ou D, Wang X, Metzger DL, James RF, Pozzilli P, Plesner A, Korneluk RG, Verchere CB, Tingle AJ. Synergistic inhibition of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human pancreatic beta cells by Bcl-2 and X-linked inhibitor of apoptosis. Human Immunology. 66: 274-84. PMID 15784465 DOI: 10.1016/J.Humimm.2004.12.002  0.366
2004 Perrelet D, Perrin FE, Liston P, Korneluk RG, MacKenzie A, Ferrer-Alcon M, Kato AC. Motoneuron resistance to apoptotic cell death in vivo correlates with the ratio between X-linked inhibitor of apoptosis proteins (XIAPs) and its inhibitor, XIAP-associated factor 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3777-85. PMID 15084658 DOI: 10.1523/Jneurosci.0413-04.2004  0.369
2004 Storbeck CJ, Daniel K, Zhang YH, Lunde J, Scime A, Asakura A, Jasmin B, Korneluk RG, Sabourin LA. Ste20-like kinase SLK displays myofiber type specificity and is involved in C2C12 myoblast differentiation. Muscle & Nerve. 29: 553-64. PMID 15052621 DOI: 10.1002/Mus.20000  0.746
2004 Storbeck CJ, Drmanic S, Daniel K, Waring JD, Jirik FR, Parry DJ, Ahmed N, Sabourin LA, Ikeda JE, Korneluk RG. Inhibition of myogenesis in transgenic mice expressing the human DMPK 3'-UTR. Human Molecular Genetics. 13: 589-600. PMID 14734627 DOI: 10.1093/Hmg/Ddh064  0.735
2003 Liston P, Fong WG, Korneluk RG. The inhibitors of apoptosis: there is more to life than Bcl2. Oncogene. 22: 8568-80. PMID 14634619 DOI: 10.1038/Sj.Onc.1207101  0.43
2003 Crocker SJ, Liston P, Anisman H, Lee CJ, Smith PD, Earl N, Thompson CS, Park DS, Korneluk RG, Robertson GS. Attenuation of MPTP-induced neurotoxicity and behavioural impairment in NSE-XIAP transgenic mice. Neurobiology of Disease. 12: 150-61. PMID 12667469 DOI: 10.1016/S0969-9961(02)00020-7  0.328
2003 Goping IS, Barry M, Liston P, Sawchuk T, Constantinescu G, Michalak KM, Shostak I, Roberts DL, Hunter AM, Korneluk R, Bleackley RC. Granzyme B-induced apoptosis requires both direct caspase activation and relief of caspase inhibition. Immunity. 18: 355-65. PMID 12648453 DOI: 10.1016/S1074-7613(03)00032-3  0.358
2003 Hunter AM, Kottachchi D, Lewis J, Duckett CS, Korneluk RG, Liston P. A novel ubiquitin fusion system bypasses the mitochondria and generates biologically active Smac/DIABLO. The Journal of Biological Chemistry. 278: 7494-9. PMID 12511567 DOI: 10.1074/Jbc.C200695200  0.381
2003 Holcík M, Gordon BW, Korneluk RG. The internal ribosome entry site-mediated translation of antiapoptotic protein XIAP is modulated by the heterogeneous nuclear ribonucleoproteins C1 and C2. Molecular and Cellular Biology. 23: 280-8. PMID 12482981 DOI: 10.1128/Mcb.23.1.280-288.2003  0.33
2003 Nevins TA, Harder ZM, Korneluk RG, Holcík M. Distinct regulation of internal ribosome entry site-mediated translation following cellular stress is mediated by apoptotic fragments of eIF4G translation initiation factor family members eIF4GI and p97/DAP5/NAT1. The Journal of Biological Chemistry. 278: 3572-9. PMID 12458215 DOI: 10.1074/Jbc.M206781200  0.36
2002 McKinnon SJ, Lehman DM, Tahzib NG, Ransom NL, Reitsamer HA, Liston P, LaCasse E, Li Q, Korneluk RG, Hauswirth WW. Baculoviral IAP repeat-containing-4 protects optic nerve axons in a rat glaucoma model. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 780-7. PMID 12027563 DOI: 10.1006/Mthe.2002.0608  0.308
2002 Holcik M, Lefebvre CA, Hicks K, Korneluk RG. Cloning and characterization of the rat homologues of the Inhibitor of Apoptosis protein 1, 2, and 3 genes. Bmc Genomics. 3: 5. PMID 11860601 DOI: 10.1186/1471-2164-3-5  0.398
2002 Perrelet D, Ferri A, Liston P, Muzzin P, Korneluk RG, Kato AC. IAPs are essential for GDNF-mediated neuroprotective effectsin injured motor neurons in vivo Nature Cell Biology. 4: 175-179. PMID 11813002 DOI: 10.1038/Ncb751  0.333
2001 Lagacé M, Xuan JY, Young SS, McRoberts C, Maier J, Rajcan-Separovic E, Korneluk RG. Genomic organization of the X-linked inhibitor of apoptosis and identification of a novel testis-specific transcript Genomics. 77: 181-188. PMID 11597143 DOI: 10.1006/Geno.2001.6635  0.386
2001 Holcik M, Gibson H, Korneluk RG. XIAP: Apoptotic brake and promising therapeutic target Apoptosis. 6: 253-261. PMID 11445667 DOI: 10.1023/A:1011379307472  0.41
2001 Holcik M, Korneluk RG. XIAP, the guardian angel Nature Reviews Molecular Cell Biology. 2: 550-556. PMID 11433370 DOI: 10.1038/35080103  0.361
2001 Conte D, Liston P, Wong JW, Wright KE, Korneluk RG. Thymocyte-targeted overexpression of xiap transgene disrupts T lymphoid apoptosis and maturation. Proceedings of the National Academy of Sciences of the United States of America. 98: 5049-54. PMID 11309492 DOI: 10.1073/Pnas.081547998  0.402
2001 Liston P, Fong WG, Kelly NL, Toji S, Miyazaki T, Conte D, Tamai K, Craig CG, McBurney MW, Korneluk RG. Identification of XAF1 as an antagonist of XIAP anti-Caspase activity. Nature Cell Biology. 3: 128-33. PMID 11175744 DOI: 10.1038/35055027  0.405
2001 Li J, Feng Q, Kim JM, Schneiderman D, Liston P, Li M, Vanderhyden B, Faught W, Fung MFK, Senterman M, Korneluk RG, Tsang BK. Human ovarian cancer and cisplatin resistance: Possible role of inhibitor of apoptosis proteins Endocrinology. 142: 370-380. PMID 11145600 DOI: 10.1210/Endo.142.1.7897  0.403
2000 Fong WG, Liston P, Rajcan-Separovic E, St. Jean M, Craig C, Korneluk RG. Expression and genetic analysis of XIAP-associated factor 1 (XAF1) in cancer cell lines Genomics. 70: 113-122. PMID 11087668 DOI: 10.1006/Geno.2000.6364  0.42
2000 Holcik M, Sonenberg N, Korneluk RG. Internal ribosome initiation of translation and the control of cell death. Trends in Genetics : Tig. 16: 469-73. PMID 11050335 DOI: 10.1016/S0168-9525(00)02106-5  0.329
2000 Holcik M, Yeh C, Korneluk RG, Chow T. Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death Oncogene. 19: 4174-4177. PMID 10962579 DOI: 10.1038/Sj.Onc.1203765  0.359
2000 Narang MA, Waring JD, Sabourin LA, Korneluk RG. Myotonic dystrophy (DM) protein kinase levels in congenital and adult DM patients. European Journal of Human Genetics : Ejhg. 8: 507-12. PMID 10909850 DOI: 10.1038/Sj.Ejhg.5200490  0.338
2000 Perrelet D, Ferri A, MacKenzie AE, Smith GM, Korneluk RG, Liston P, Sagot Y, Terrado J, Monnier D, Kato AC. IAP family proteins delay motoneuron cell death in vivo European Journal of Neuroscience. 12: 2059-2067. PMID 10886345 DOI: 10.1046/J.1460-9568.2000.00098.X  0.374
2000 Holcik M, Korneluk RG. Functional characterization of the X-linked inhibitor of apoptosis (XIAP) internal ribosome entry site element: Role of la autoantigen in XIAP translation Molecular and Cellular Biology. 20: 4648-4657. PMID 10848591 DOI: 10.1128/Mcb.20.13.4648-4657.2000  0.387
2000 Holcik M, Thompson CS, Yaraghi Z, Lefebvre CA, MacKenzie AE, Korneluk RG. The hippocampal neurons of neuronal apoptosis inhibitory protein 1 (NAIP1)-deleted mice display increased vulnerability to kainic acid-induced injury. Proceedings of the National Academy of Sciences of the United States of America. 97: 2286-90. PMID 10681452 DOI: 10.1073/Pnas.040469797  0.349
2000 Narang M, Waring J, Sabourin L, Rajcan-Separovic E, Parry D, Jirik F, Korneluk R. Skeletal myopathy in mice over-expressing the human myotonic dystrophy protein kinase (DMPK) gene Gene Function & Disease. 1: 134-144. DOI: 10.1002/1438-826X(200010)1:3/4<134::Aid-Gnfd134>3.0.Co;2-W  0.397
1999 Holcik M, Lefebvre C, Yeh C, Chow T, Korneluk RG. A new internal-ribosome-entry-site motif potentiates XIAP-mediated cytoprotection. Nature Cell Biology. 1: 190-2. PMID 10559907 DOI: 10.1038/11109  0.388
1999 Xu D, Bureau Y, McIntyre DC, Nicholson DW, Liston P, Zhu Y, Fong WG, Crocker SJ, Korneluk RG, Robertson GS. Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein overexpression in the rat hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 5026-33. PMID 10366635 DOI: 10.1523/Jneurosci.19-12-05026.1999  0.321
1999 Young SS, Liston P, Xuan JY, McRoberts C, Lefebvre CA, Korneluk RG. Genomic organization and physical map of the human inhibitors of apoptosis: HIAP1 and HIAP2 Mammalian Genome. 10: 44-48. PMID 9892732 DOI: 10.1007/S003359900940  0.337
1999 Simons M, Beinroth S, Gleichmann M, Liston P, Korneluk RG, MacKenzie AE, Bähr M, Klockgether T, Robertson GS, Weller M, Schulz JB. Adenovirus-mediated gene transfer of inhibitors of apoptosis protein delays apoptosis in cerebellar granule neurons. Journal of Neurochemistry. 72: 292-301. PMID 9886081 DOI: 10.1046/J.1471-4159.1999.0720292.X  0.378
1998 LaCasse EC, Baird S, Korneluk RG, MacKenzie AE. The inhibitors of apoptosis (IAPs) and their emerging role in cancer Oncogene. 17: 3247-3259. PMID 9916987 DOI: 10.1038/Sj.Onc.1202569  0.395
1998 Yaraghi Z, Korneluk RG, MacKenzie A. Cloning and characterization of the multiple murine homologues of NAIP (neuronal apoptosis inhibitory protein) Genomics. 51: 107-113. PMID 9693038 DOI: 10.1006/Geno.1998.5378  0.384
1998 Storbeck CJ, Sabourin LA, Waring JD, Korneluk RG. Definition of regulatory sequence elements in the promoter region and the first intron of the myotonic dystrophy protein kinase gene. The Journal of Biological Chemistry. 273: 9139-47. PMID 9535904 DOI: 10.1074/Jbc.273.15.9139  0.748
1998 Chen Q, Baird SD, Mahadevan M, Besner-Johnston A, Farahani R, Xuan J, Kang X, Lefebvre C, Ikeda JE, Korneluk RG, MacKenzie AE. Sequence of a 131-kb region of 5q13.1 containing the spinal muscular atrophy candidate genes SMN and NAIP. Genomics. 48: 121-7. PMID 9503025 DOI: 10.1006/Geno.1997.5141  0.35
1998 Li J, Kim JM, Liston P, Li M, Miyazaki T, Mackenzie AE, Korneluk RG, Tsang BK. Expression of inhibitor of apoptosis proteins (IAPs) in rat granulosa cells during ovarian follicular development and atresia Endocrinology. 139: 1321-1328. PMID 9492068 DOI: 10.1210/Endo.139.3.5850  0.398
1997 Liston P, Lefebvre C, Fong WG, Xuan JY, Korneluk RG. Genomic characterization of the mouse inhibitor of apoptosis protein 1 and 2 genes Genomics. 46: 495-503. PMID 9441758 DOI: 10.1006/Geno.1997.5059  0.4
1997 Lafrenière RG, Kibar Z, Rochefort DL, Han FY, Fon EA, Dubé MP, Kang X, Baird S, Korneluk RG, Rommens JM, Rouleau GA. Genomic structure of the human GT334 (EHOC-1) gene mapping to 21q22.3. Gene. 198: 313-21. PMID 9370297 DOI: 10.1016/S0378-1119(97)00333-8  0.353
1997 Sabourin LA, Tamai K, Narang MA, Korneluk RG. Overexpression of 3'-untranslated region of the myotonic dystrophy kinase cDNA inhibits myoblast differentiation in vitro Journal of Biological Chemistry. 272: 29626-29635. PMID 9368029 DOI: 10.1074/Jbc.272.47.29626  0.406
1997 Farahani R, Fong WG, Korneluk RG, MacKenzie AE. Genomic organization and primary characterization of miap-3: The murine homologue of human X-linked IAP Genomics. 42: 514-518. PMID 9205126 DOI: 10.1006/Geno.1997.4742  0.41
1997 Somerville MJ, Hunter AGW, Aubry HL, Korneluk RG, MacKenzie AE, Surh LC. Clinical application of the molecular diagnosis of spinal muscular atrophy: Deletions of neuronal apoptosis inhibitor protein and survival motor neuron genes American Journal of Medical Genetics. 69: 159-165. PMID 9056553 DOI: 10.1002/(Sici)1096-8628(19970317)69:2<159::Aid-Ajmg8>3.0.Co;2-K  0.339
1997 Korneluk RG, MacKenzie AE, Robertson GS. Inhibition of apoptosis proteins (IAPs) and neurodegenerative disease Biochemistry and Cell Biology. 75: 471. DOI: 10.1139/Abstract18  0.33
1997 Liston P, Young SS, Mackenzie AE, Korneluk RG. Life and death decisions: The role of the IAPs in modulating programmed cell death Apoptosis. 2: 423-441. DOI: 10.1023/A:1026465926478  0.406
1997 Vitté-Mony I, Korneluk RG, Diaz-Mitoma F. Role of XIAP protein, a human member of the inhibitor of apoptosis (IAP) protein family, in phytohemagglutinin-induced apoptosis of human T cell lines Apoptosis. 2: 501-509. DOI: 10.1023/A:1026434514183  0.425
1997 Korneluk RG, MacKenzie AE, Baird S, Liston P. Mammalian apoptosis inhibitor protein gene family, primers, probes and detection methods Biofutur. 1997: 46. DOI: 10.1016/S0294-3506(99)80334-2  0.39
1996 Lafrenière RG, Rochefort DL, Kibar Z, Fon EA, Han F, Cochius J, Kang X, Baird S, Korneluk RG, Andermann E, Rommens JM, Rouleau GA. Isolation and characterization of GT335, a novel human gene conserved in Escherichia coli and mapping to 21q22.3. Genomics. 38: 264-72. PMID 8975701 DOI: 10.1006/Geno.1996.0627  0.374
1996 Rajcan-Separovic E, Liston P, Lefebvre C, Korneluk RG. Assignment of human inhibitor of apoptosis protein (IAP) genes xiap, hiap-1, and hiap-2 to chromosomes Xq25 and 11q22-q23 by fluorescence in situ hybridization Genomics. 37: 404-406. PMID 8938457 DOI: 10.1006/Geno.1996.0579  0.341
1996 Yokoi H, Shimizu Y, Anazawa H, Lefebvre CA, Korneluk RG, Ikeda JE. The structure and complete nucleotide sequence of the human cyclophilin 40 (PPID) gene Genomics. 35: 448-455. PMID 8812478 DOI: 10.1006/Geno.1996.0384  0.37
1996 Shutler G, Glassco T, Kang X, Korneluk R, Mueller CR. Genomic structure of the human D-site binding protein (DBP) gene. Genomics. 34: 334-9. PMID 8786133 DOI: 10.1006/Geno.1996.0295  0.351
1996 Waring JD, Haq R, Tamai K, Sabourin LA, Ikeda JE, Korneluk RG. Investigation of myotonic dystrophy kinase isoform translocation and membrane association. The Journal of Biological Chemistry. 271: 15187-93. PMID 8663097 DOI: 10.1074/Jbc.271.25.15187  0.302
1996 Phelan CM, Larsson C, Baird S, Futreal PA, Ruttledge MH, Morgan K, Tonin P, Hung H, Korneluk RG, Pollak MN, Narod SA. The human mammary-derived growth inhibitor (MDGI) gene: Genomic structure and mutation analysis in human breast tumors Genomics. 34: 63-68. PMID 8661024 DOI: 10.1006/Geno.1996.0241  0.325
1996 Liston P, Roy N, Tamai K, Lefebvre C, Baird S, Cherton-Horvat G, Farahani R, McLean M, Ikeda JE, MacKenzie A, Korneluk RG. Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes Nature. 379: 349-353. PMID 8552191 DOI: 10.1038/379349A0  0.457
1995 MAHADEVAN MS, BAIRD S, BAILLY JE, SHUTLER GG, SABOURIN LA, TSILFIDIS C, NEVILLE CE, NARANG M, KORNELUK RG. Isolation of a Novel G Protein-Coupled Receptor (GPR4) Localized to Chromosome 19q13.3 Genomics. 30: 84-88. PMID 8595909 DOI: 10.1006/Geno.1995.0013  0.341
1995 Roy N, Mahadevan MS, McLean M, Shutter G, Yaraghi Z, Farahani R, Baird S, Besner-Johnston A, Lefebvre C, Kang X, Salih M, Aubry H, Tamai K, Guan X, Ioannou P, ... ... Korneluk RG, et al. The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy Cell. 80: 167-178. PMID 7813013 DOI: 10.1016/0092-8674(95)90461-1  0.369
1995 Mahadevan MS, Korneluk RG, Roy N, Mackenzie A, Ikeda JE. SMA genes: Deleted and duplicated Nature Genetics. 9: 112-113. PMID 7719336 DOI: 10.1038/Ng0295-112  0.311
1995 Whiting EJ, Waring JD, Tamai K, Somerville MJ, Hincke M, Staines WA, Ikeda JE, Korneluk RG. Characterization of myotonic dystrophy kinase (DMK) protein in human and rodent muscle and central nervous tissue. Human Molecular Genetics. 4: 1063-72. PMID 7655460 DOI: 10.1093/Hmg/4.6.1063  0.376
1995 Yaraghi Z, McLean MD, Roy N, Surh L, Ikeda JE, Korneluk RG, MacKenzie A. A recombination event occurring within two complex 5q13.1 microsatellite repeat polymorphisms suggests a telomeric mapping of spinal muscular atrophy Human Genetics. 96: 330-334. PMID 7649551 DOI: 10.1007/Bf00210417  0.326
1995 Roy N, Mclean MD, Besner-Johnston A, Lefebvre C, Salih M, Carpten JD, Burghes AHM, Yaraghi Z, Ikeda JE, Korneluk RG, Mackenzie AE. Refined physical map of the spinal muscular atrophy gene (SMA) region at 5q13 based on YAC and cosmid contiguous arrays Genomics. 26: 451-460. PMID 7607667 DOI: 10.1016/0888-7543(95)80162-F  0.328
1993 Mahadevan MS, Foitzik MA, Surh LC, Korneluk RG. Characterization and Polymerase Chain Reaction (PCR) Detection of an Alu Deletion Polymorphism in Total Linkage Disequilibrium with Myotonic Dystrophy Genomics. 15: 446-448. PMID 8449517 DOI: 10.1006/Geno.1993.1087  0.335
1993 Sabouri LA, Mahadevan MS, Narang M, Lee DSC, Surh LC, Korneluk RG. Effect of the myotonic dystrophy (DM) mutation on mRNA levels of the DM gene Nature Genetics. 4: 233-238. PMID 8358430 DOI: 10.1038/Ng0793-233  0.302
1993 O'Hoy KL, Tsilfidis C, Mahadevan MS, Neville CE, Barceló J, Hunter AGW, Korneluk RG. Reduction in size of the myotonic dystrophy trinucleotide repeat mutation during transmission Science. 259: 809-812. PMID 8094260 DOI: 10.1126/Science.8094260  0.316
1992 Shutler G, Korneluk RG, Tsilfidis C, Mahadevan M, Bailly J, Smeets H, Jansen G, Wieringa B, Lohman F, Aslanidis C, de Jong PJ. Physical mapping and cloning of the proximal segment of the myotonic dystrophy gene region Genomics. 13: 518-525. PMID 1639380 DOI: 10.1016/0888-7543(92)90119-D  0.33
1991 Bailly J, MacKenzie AE, Leblond S, Korneluk RG. Assessment of a creatine kinase isoform M defect as a cause of myotonic dystrophy and the characterization of two novel CKMM polymorphisms Human Genetics. 86: 457-462. PMID 2016086 DOI: 10.1007/Bf00194633  0.352
1991 MacKenzie AE, MacLeod HL, Leblond SC, Monteith N, Lahey D, Korneluk RG. DNA polymorphism and linkage disequilibrium within the apolipoprotein CII locus on human chromosome 19. Human Heredity. 41: 188-94. PMID 1682238 DOI: 10.1159/000153999  0.313
1991 Shutler G, MacKenzie AE, Brunner H, Wieringa B, de Jong P, Lohman FP, Leblond S, Bailly J, Korneluk RG. Physical and genetic mapping of a novel chromosome 19 ERCC1 marker showing close linkage with myotonic dystrophy Genomics. 9: 500-504. PMID 1674498 DOI: 10.1016/0888-7543(91)90416-C  0.313
1990 MacLennan DH, Duff C, Zorzato F, Fujii J, Phillips M, Korneluk RG, Frodis W, Britt BA, Worton RG. Ryanodine receptor gene is a candidate for predisposition to malignant hyperthermia. Nature. 343: 559-61. PMID 1967823 DOI: 10.1038/343559A0  0.368
1989 Brunner HG, Korneluk RG, Coerwinkel-Driessen M, MacKenzie A, Smeets H, Lambermon HM, van Oost BA, Wieringa B, Ropers HH. Myotonic dystrophy is closely linked to the gene for muscle-type creatine kinase (CKMM). Human Genetics. 81: 308-10. PMID 2703233 DOI: 10.1007/Bf00283680  0.357
1989 Korneluk RG, MacKenzie AE, Nakamura Y, Dubé I, Jacob P, Hunter AG. A reordering of human chromosome 19 long-arm DNA markers and identification of markers flanking the myotonic dystrophy locus. Genomics. 5: 596-604. PMID 2613241 DOI: 10.1016/0888-7543(89)90028-1  0.325
1989 Korneluk RG, MacLeod HL, McKeithan TW, Brooks JD, MacKenzie AE. A chromosome 19 clone from a translocation breakpoint shows close linkage and linkage disequilibrium with myotonic dystrophy Genomics. 4: 146-151. PMID 2567698 DOI: 10.1016/0888-7543(89)90293-0  0.312
1987 Korneluk RG, Macleod HL, Leblond SC, Monteith NL, Baralle FE, Hunter AGW. Avall RFLP at the human apolipoprotein CII (APO CII) gene locus Nucleic Acids Research. 15: 6769. PMID 2888095 DOI: 10.1093/Nar/15.16.6769  0.309
1985 Kittur SD, Hoppener JW, Antonarakis SE, Daniels JD, Meyers DA, Maestri NE, Jansen M, Korneluk RG, Nelkin BD, Kazazian HH. Linkage map of the short arm of human chromosome 11: location of the genes for catalase, calcitonin, and insulin-like growth factor II. Proceedings of the National Academy of Sciences of the United States of America. 82: 5064-7. PMID 2991908 DOI: 10.1073/Pnas.82.15.5064  0.309
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