| Year |
Citation |
Score |
| 2024 |
Blades B, Hung YH, Belaidi AA, Volitakis I, Schultz AG, Cater MA, Cheung NS, Bush AI, Ayton S, La Fontaine S. Impaired cellular copper regulation in the presence of ApoE4. Journal of Neurochemistry. PMID 39135362 DOI: 10.1111/jnc.16198 |
0.3 |
|
| 2024 |
Ma L, Tan ECK, Bush AI, Masters CL, Goudey B, Jin L, Pan Y, Group AR. Elucidating the Link Between Anxiety/Depression and Alzheimer's Dementia in the Australian Imaging Biomarkers and Lifestyle (AIBL) Study. Journal of Epidemiology and Global Health. PMID 38896210 DOI: 10.1007/s44197-024-00266-w |
0.399 |
|
| 2023 |
Su H, Masters CL, Bush AI, Barnham KJ, Reid GE, Vella LJ. Exploring the significance of lipids in Alzheimer's disease and the potential of extracellular vesicles. Proteomics. e2300063. PMID 37654087 DOI: 10.1002/pmic.202300063 |
0.428 |
|
| 2023 |
Lane DJR, Alves F, Ayton S, Bush AI. Striking a NRF2: The rusty and rancid vulnerabilities toward ferroptosis in Alzheimer's disease. Antioxidants & Redox Signaling. PMID 37212212 DOI: 10.1089/ars.2023.0318 |
0.348 |
|
| 2022 |
Ayton S, Janelidze S, Kalinowski P, Palmqvist S, Belaidi AA, Stomrud E, Roberts A, Roberts B, Hansson O, Bush AI. CSF ferritin in the clinicopathological progression of Alzheimer's disease and associations with APOE and inflammation biomarkers. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 36357168 DOI: 10.1136/jnnp-2022-330052 |
0.356 |
|
| 2022 |
Agarwal P, Ayton S, Agrawal S, Dhana K, Bennett DA, Barnes LL, Leurgans SE, Bush AI, Schneider JA. Brain copper may protect from cognitive decline and Alzheimer's disease pathology: a community-based study. Molecular Psychiatry. PMID 36195639 DOI: 10.1038/s41380-022-01802-5 |
0.311 |
|
| 2022 |
Mandal PK, Goel A, Bush AI, Punjabi K, Joon S, Mishra R, Tripathi M, Garg A, Kumar NK, Sharma P, Shukla D, Ayton SJ, Fazlollahi A, Maroon JC, Dwivedi D, et al. Hippocampal glutathione depletion with enhanced iron level in patients with mild cognitive impairment and Alzheimer's disease compared with healthy elderly participants. Brain Communications. 4: fcac215. PMID 36072647 DOI: 10.1093/braincomms/fcac215 |
0.315 |
|
| 2022 |
Pedrini S, Doecke JD, Hone E, Wang P, Thota R, Bush AI, Rowe CC, Dore V, Villemagne VL, Ames D, Rainey-Smith S, Verdile G, Sohrabi HR, Raida MR, Taddei K, et al. Plasma high-density lipoprotein cargo is altered in Alzheimer's disease and is associated with regional brain volume. Journal of Neurochemistry. PMID 36000528 DOI: 10.1111/jnc.15681 |
0.686 |
|
| 2022 |
Cadby G, Giles C, Melton PE, Huynh K, Mellett NA, Duong T, Nguyen A, Cinel M, Smith A, Olshansky G, Wang T, Brozynska M, Inouye M, McCarthy NS, Ariff A, ... ... Bush AI, et al. Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease. Nature Communications. 13: 3124. PMID 35668104 DOI: 10.1038/s41467-022-30875-7 |
0.435 |
|
| 2022 |
Dhiman K, Villemagne VL, Fowler C, Bourgeat P, Li QX, Collins S, Bush AI, Rowe CC, Masters CL, Ames D, Blennow K, Zetterberg H, Martins RN, Gupta V. Cerebrospinal Fluid Neurofilament Light Predicts Risk of Dementia Onset in Cognitively Healthy Individuals and Rate of Cognitive Decline in Mild Cognitive Impairment: A Prospective Longitudinal Study. Biomedicines. 10. PMID 35625782 DOI: 10.3390/biomedicines10051045 |
0.505 |
|
| 2022 |
Belaidi AA, Masaldan S, Southon A, Kalinowski P, Acevedo K, Appukuttan AT, Portbury S, Lei P, Agarwal P, Leurgans SE, Schneider J, Conrad M, Bush AI, Ayton S. Apolipoprotein E potently inhibits ferroptosis by blocking ferritinophagy. Molecular Psychiatry. PMID 35484240 DOI: 10.1038/s41380-022-01568-w |
0.328 |
|
| 2022 |
Doré V, Doecke JD, Saad ZS, Triana-Baltzer G, Slemmon R, Krishnadas N, Bourgeat P, Huang K, Burnham S, Fowler C, Rainey-Smith SR, Bush AI, Ward L, Robertson J, Martins RN, et al. Plasma p217+tau versus NAV4694 amyloid and MK6240 tau PET across the Alzheimer's continuum. Alzheimer's & Dementia (Amsterdam, Netherlands). 14: e12307. PMID 35415202 DOI: 10.1002/dad2.12307 |
0.509 |
|
| 2022 |
Laffoon SB, Doecke JD, Roberts AM, Vance JA, Reeves BD, Pertile KK, Rumble RL, Fowler CJ, Trounson B, Ames D, Martins R, Bush AI, Masters CL, Grieco PA, Dratz EA, et al. Analysis of plasma proteins using 2D gels and novel fluorescent probes: in search of blood based biomarkers for Alzheimer's disease. Proteome Science. 20: 2. PMID 35081972 DOI: 10.1186/s12953-021-00185-9 |
0.517 |
|
| 2022 |
Wang T, Huynh K, Giles C, Mellett NA, Duong T, Nguyen A, Lim WLF, Smith AA, Olshansky G, Cadby G, Hung J, Hui J, Beilby J, Watts GF, Chatterjee P, ... ... Bush AI, et al. APOE ε2 resilience for Alzheimer's disease is mediated by plasma lipid species: Analysis of three independent cohort studies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35077012 DOI: 10.1002/alz.12538 |
0.537 |
|
| 2021 |
Finkelstein DI, Billings JL, Adlard PA, Ayton S, Sedjahtera A, Masters CL, Wilkins S, Shackleford DM, Charman SA, Bal W, Zawisza IA, Kurowska E, Gundlach AL, Ma S, Bush AI, et al. Correction to: The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson's disease. Acta Neuropathologica Communications. 9: 161. PMID 34588001 DOI: 10.1186/s40478-021-01258-8 |
0.354 |
|
| 2021 |
Jakaria M, Belaidi AA, Bush AI, Ayton S. Ferroptosis as a mechanism of neurodegeneration in Alzheimer's disease. Journal of Neurochemistry. 159: 804-825. PMID 34553778 DOI: 10.1111/jnc.15519 |
0.362 |
|
| 2021 |
Tsatsanis A, McCorkindale AN, Wong BX, Patrick E, Ryan TM, Evans RW, Bush AI, Sutherland GT, Sivaprasadarao A, Guennewig B, Duce JA. The acute phase protein lactoferrin is a key feature of Alzheimer's disease and predictor of Aβ burden through induction of APP amyloidogenic processing. Molecular Psychiatry. PMID 34400772 DOI: 10.1038/s41380-021-01248-1 |
0.36 |
|
| 2021 |
Fowler C, Rainey-Smith SR, Bird S, Bomke J, Bourgeat P, Brown BM, Burnham SC, Bush AI, Chadunow C, Collins S, Doecke J, Doré V, Ellis KA, Evered L, Fazlollahi A, et al. Fifteen Years of the Australian Imaging, Biomarkers and Lifestyle (AIBL) Study: Progress and Observations from 2,359 Older Adults Spanning the Spectrum from Cognitive Normality to Alzheimer's Disease. Journal of Alzheimer's Disease Reports. 5: 443-468. PMID 34368630 DOI: 10.3233/ADR-210005 |
0.56 |
|
| 2021 |
Ayton S, Portbury S, Kalinowski P, Agarwal P, Diouf I, Schneider JA, Morris MC, Bush AI. Regional brain iron associated with deterioration in Alzheimer's disease: A large cohort study and theoretical significance. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33491917 DOI: 10.1002/alz.12282 |
0.324 |
|
| 2020 |
Lei P, Ayton S, Bush AI. The Essential Elements of Alzheimer's Disease. The Journal of Biological Chemistry. PMID 33219130 DOI: 10.1074/jbc.REV120.008207 |
0.377 |
|
| 2020 |
Ayton S, Bush AI. β-amyloid: the known unknowns. Ageing Research Reviews. 101212. PMID 33188924 DOI: 10.1016/j.arr.2020.101212 |
0.351 |
|
| 2020 |
Huynh K, Lim WLF, Giles C, Jayawardana KS, Salim A, Mellett NA, Smith AAT, Olshansky G, Drew BG, Chatterjee P, Martins I, Laws SM, Bush AI, Rowe CC, Villemagne VL, et al. Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer's disease. Nature Communications. 11: 5698. PMID 33173055 DOI: 10.1038/s41467-020-19473-7 |
0.525 |
|
| 2020 |
Gleason A, Bush AI. Iron and Ferroptosis as Therapeutic Targets in Alzheimer's Disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 33111259 DOI: 10.1007/s13311-020-00954-y |
0.331 |
|
| 2020 |
Zhou Y, Zhu F, Liu Y, Zheng M, Wang Y, Zhang D, Anraku Y, Zou Y, Li J, Wu H, Pang X, Tao W, Shimoni O, Bush AI, Xue X, et al. Blood-brain barrier-penetrating siRNA nanomedicine for Alzheimer's disease therapy. Science Advances. 6. PMID 33036977 DOI: 10.1126/sciadv.abc7031 |
0.31 |
|
| 2020 |
Beauchamp LC, Liu XM, Sedjahtera A, Bogeski M, Vella LJ, Bush AI, Adlard PA, Barnham KJ. S-Adenosylmethionine Rescues Cognitive Deficits in the rTg4510 Animal Model by Stabilizing Protein Phosphatase 2A and Reducing Phosphorylated Tau. Journal of Alzheimer's Disease : Jad. PMID 32925070 DOI: 10.3233/Jad-200756 |
0.382 |
|
| 2020 |
Ayton S, Janelidze S, Roberts B, Palmqvist S, Kalinowski P, Diouf I, Belaidi AA, Stomrud E, Bush AI, Hansson O. Acute phase markers in CSF reveal inflammatory changes in Alzheimer's disease that intersect with pathology, APOE ε4, sex and age. Progress in Neurobiology. 101904. PMID 32882319 DOI: 10.1016/J.Pneurobio.2020.101904 |
0.437 |
|
| 2020 |
Gleason A, Ayton S, Bush AI. Unblinded by the light: amyloid-related imaging abnormalities in Alzheimer's clinical trials. European Journal of Neurology. PMID 32808453 DOI: 10.1111/Ene.14484 |
0.367 |
|
| 2020 |
Rao SS, Portbury SD, Lago L, Bush AI, Adlard PA. The Iron Chelator Deferiprone Improves the Phenotype in a Mouse Model of Tauopathy. Journal of Alzheimer's Disease : Jad. PMID 32741833 DOI: 10.3233/Jad-200551 |
0.459 |
|
| 2020 |
Pedrini S, Hone E, Gupta VB, James I, Teimouri E, Bush AI, Rowe CC, Villemagne VL, Ames D, Masters CL, Rainey-Smith S, Verdile G, Sohrabi HR, Raida MR, Wenk MR, et al. Plasma High Density Lipoprotein Small Subclass is Reduced in Alzheimer's Disease Patients and Correlates with Cognitive Performance. Journal of Alzheimer's Disease : Jad. PMID 32741823 DOI: 10.3233/Jad-200291 |
0.708 |
|
| 2020 |
Fazlollahi A, Raniga P, Bourgeat P, Yates P, Bush AI, Salvado O, Ayton S. Restricted Effect of Cerebral Microbleeds on Regional Magnetic Susceptibility. Journal of Alzheimer's Disease : Jad. PMID 32538840 DOI: 10.3233/Jad-200076 |
0.419 |
|
| 2020 |
Datki Z, Galik-Olah Z, Janosi-Mozes E, Szegedi V, Kalman J, Hunya ÁG, Fulop L, Tamano H, Takeda A, Adlard PA, Bush AI. Alzheimer risk factors age and female sex induce cortical Aβ aggregation by raising extracellular zinc. Molecular Psychiatry. PMID 32518388 DOI: 10.1038/S41380-020-0800-Y |
0.428 |
|
| 2020 |
Tamano H, Ishikawa Y, Shioya A, Itoh R, Oneta N, Shimaya R, Egawa M, Adlard PA, Bush AI, Takeda A. Adrenergic β receptor activation reduces amyloid β-mediated intracellular Zn toxicity in dentate granule cells followed by rescuing impairment of dentate gyrus LTP. Neurotoxicology. 79: 177-183. PMID 32512026 DOI: 10.1016/J.Neuro.2020.06.001 |
0.365 |
|
| 2020 |
Lim WLF, Huynh K, Chatterjee P, Martins I, Jayawardana KS, Giles C, Mellett NA, Laws SM, Bush AI, Rowe CC, Villemagne VL, Ames D, Drew BG, Masters CL, Meikle PJ, et al. Relationships Between Plasma Lipids Species, Gender, Risk Factors, and Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 32474467 DOI: 10.3233/Jad-191304 |
0.595 |
|
| 2020 |
Tsatsanis A, Wong BX, Gunn AP, Ayton S, Bush AI, Devos D, Duce JA. Amyloidogenic processing of Alzheimer's disease β-amyloid precursor protein induces cellular iron retention. Molecular Psychiatry. PMID 32444869 DOI: 10.1038/S41380-020-0762-0 |
0.44 |
|
| 2020 |
Dhiman K, Gupta VB, Villemagne VL, Eratne D, Graham PL, Fowler C, Bourgeat P, Li QX, Collins S, Bush AI, Rowe CC, Masters CL, Ames D, Hone E, Blennow K, et al. Cerebrospinal fluid neurofilament light concentration predicts brain atrophy and cognition in Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12005. PMID 32211500 DOI: 10.1002/Dad2.12005 |
0.626 |
|
| 2020 |
Hung YH, Lotan A, Yeshurun S, Schroeder A, Bush AI. Iron chelation by deferiprone does not rescue the Niemann-Pick Disease Type C1 mouse model. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. PMID 32100150 DOI: 10.1007/S10534-020-00233-5 |
0.351 |
|
| 2020 |
Diouf I, Bush AI, Ayton S. Cerebrospinal fluid ceruloplasmin levels predict cognitive decline and brain atrophy in people with underlying β-amyloid pathology. Neurobiology of Disease. 104810. PMID 32087292 DOI: 10.1016/J.Nbd.2020.104810 |
0.461 |
|
| 2020 |
Hancock SM, Portbury SD, Gunn AP, Roberts BR, Bush AI, Adlard PA. Zinc Transporter-3 Knockout Mice Demonstrate Age-Dependent Alterations in the Metalloproteome. International Journal of Molecular Sciences. 21. PMID 32012946 DOI: 10.3390/Ijms21030839 |
0.343 |
|
| 2019 |
Tamano H, Takiguchi M, Tanaka Y, Murakami T, Adlard PA, Bush AI, Takeda A. Preferential Neurodegeneration in the Dentate Gyrus by Amyloid β-Induced Intracellular ZnDysregulation and Its Defense Strategy. Molecular Neurobiology. PMID 31865526 DOI: 10.1007/S12035-019-01853-W |
0.399 |
|
| 2019 |
Southon AA, Szostak K, Acevedo KM, Dent KA, Volitakis I, Belaidi AA, Barnham KJ, Crouch PJ, Ayton S, Donnelly PS, Bush AI. Cu (atsm) inhibits ferroptosis: implications for treatment of neurodegenerative disease. British Journal of Pharmacology. PMID 31655003 DOI: 10.1111/Bph.14881 |
0.327 |
|
| 2019 |
Acevedo K, Masaldan S, Opazo CM, Bush AI. Redox active metals in neurodegenerative diseases. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 31650248 DOI: 10.1007/S00775-019-01731-9 |
0.348 |
|
| 2019 |
Ayton S, Lei P, Appukuttan AT, Renoir T, Foliaki S, Chen F, Adlard PA, Hannan AJ, Bush AI. Brain Zinc Deficiency Exacerbates Cognitive Decline in the R6/1 Model of Huntington's Disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 31520307 DOI: 10.1007/S13311-019-00785-6 |
0.339 |
|
| 2019 |
Masaldan S, Belaidi AA, Ayton S, Bush AI. Cellular Senescence and Iron Dyshomeostasis in Alzheimer's Disease. Pharmaceuticals (Basel, Switzerland). 12. PMID 31248150 DOI: 10.3390/Ph12020093 |
0.41 |
|
| 2019 |
Tamano H, Takiguchi M, Shimaya R, Adlard PA, Bush AI, Takeda A. Extracellular Zn-independently attenuated LTP by human amyloid β and rat amyloid β. Biochemical and Biophysical Research Communications. PMID 31084925 DOI: 10.1016/J.Bbrc.2019.05.037 |
0.382 |
|
| 2019 |
Tamano H, Oneta N, Shioya A, Adlard PA, Bush AI, Takeda A. In vivo synaptic activity-independent co-uptakes of amyloid β and Zn into dentate granule cells in the normal brain. Scientific Reports. 9: 6498. PMID 31019269 DOI: 10.1038/S41598-019-43012-0 |
0.401 |
|
| 2019 |
Ayton S, Wang Y, Diouf I, Schneider JA, Brockman J, Morris MC, Bush AI. Brain iron is associated with accelerated cognitive decline in people with Alzheimer pathology. Molecular Psychiatry. PMID 30778133 DOI: 10.1038/S41380-019-0375-7 |
0.411 |
|
| 2019 |
Ashton NJ, Nevado-Holgado AJ, Barber IS, Lynham S, Gupta V, Chatterjee P, Goozee K, Hone E, Pedrini S, Blennow K, Schöll M, Zetterberg H, Ellis KA, Bush AI, Rowe CC, et al. A plasma protein classifier for predicting amyloid burden for preclinical Alzheimer's disease. Science Advances. 5: eaau7220. PMID 30775436 DOI: 10.1126/Sciadv.Aau7220 |
0.613 |
|
| 2019 |
McInerney MP, Pan Y, Volitakis I, Bush AI, Short JL, Nicolazzo JA. The effects of clioquinol on P-glycoprotein expression and biometal distribution in the mouse brain microvasculature. Journal of Pharmaceutical Sciences. PMID 30738852 DOI: 10.1016/J.Xphs.2019.01.030 |
0.303 |
|
| 2019 |
Bray L, Volitakis I, Ayton S, Bush AI, Adlard PA. Zn-DTSM, A Zinc Ionophore with Therapeutic Potential for Acrodermatitis Enteropathica? Nutrients. 11. PMID 30669644 DOI: 10.3390/Nu11010206 |
0.308 |
|
| 2019 |
Tamano H, Suzuki H, Kobuchi S, Adlard PA, Bush AI, Takeda A. Difference in ability for extracellular Zn influx between human and rat amyloid β and its significance. Neurotoxicology. PMID 30664975 DOI: 10.1016/J.Neuro.2019.01.005 |
0.409 |
|
| 2019 |
Nikseresht S, Bush AI, Ayton S. Treating Alzheimer's disease by targeting iron. British Journal of Pharmacology. PMID 30632143 DOI: 10.1111/Bph.14567 |
0.426 |
|
| 2019 |
Cimdins K, Waugh HS, Chrysostomou V, Lopez Sanchez MIG, Johannsen VA, Cook MJ, Crowston JG, Hill AF, Duce JA, Bush AI, Trounce IA. Amyloid Precursor Protein Mediates Neuronal Protection from Rotenone Toxicity. Molecular Neurobiology. PMID 30612335 DOI: 10.1007/S12035-018-1460-7 |
0.319 |
|
| 2018 |
Diouf I, Fazlollahi A, Bush AI, Ayton S. Cerebrospinal fluid ferritin levels predict brain hypometabolism in people with underlying β-amyloid pathology. Neurobiology of Disease. 124: 335-339. PMID 30557658 DOI: 10.1016/J.Nbd.2018.12.010 |
0.441 |
|
| 2018 |
Xiao Z, La Fontaine S, Bush AI, Wedd AG. Molecular Mechanisms of Glutaredoxin Enzymes: Versatile Hubs for Thiol-Disulfide Exchange between Protein Thiols and Glutathione. Journal of Molecular Biology. PMID 30552876 DOI: 10.1016/J.Jmb.2018.12.006 |
0.306 |
|
| 2018 |
Tamano H, Suzuki H, Murakami T, Fujii H, Adlard PA, Bush AI, Takeda A. Amyloid β-Induced Rapid Zn Influx into Dentate Granule Cells Attenuates Maintained LTP Followed by Retrograde Amnesia. Molecular Neurobiology. PMID 30460616 DOI: 10.1007/S12035-018-1429-6 |
0.37 |
|
| 2018 |
Masaldan S, Bush AI, Devos D, Rolland AS, Moreau C. Striking while the iron is hot: Iron metabolism and Ferroptosis in neurodegeneration. Free Radical Biology & Medicine. PMID 30266679 DOI: 10.1016/J.Freeradbiomed.2018.09.033 |
0.368 |
|
| 2018 |
Cardoso BR, Roberts BR, Malpas CB, Vivash L, Genc S, Saling MM, Desmond P, Steward C, Hicks RJ, Callahan J, Brodtmann A, Collins S, Macfarlane S, Corcoran NM, Hovens CM, ... ... Bush AI, et al. Supranutritional Sodium Selenate Supplementation Delivers Selenium to the Central Nervous System: Results from a Randomized Controlled Pilot Trial in Alzheimer's Disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 30215171 DOI: 10.1007/S13311-018-0662-Z |
0.388 |
|
| 2018 |
Sedjahtera A, Gunawan L, Bray L, Hung LW, Parsons J, Okamura N, Villemagne VL, Yanai K, Liu XM, Chan J, Bush AI, Finkelstein DI, Barnham KJ, Cherny RA, Adlard PA. Targeting metals rescues the phenotype in an animal model of tauopathy. Metallomics : Integrated Biometal Science. PMID 30168573 DOI: 10.1039/C8Mt00153G |
0.427 |
|
| 2018 |
Venkataramani V, Doeppner TR, Willkommen D, Cahill CM, Xin Y, Ye G, Liu Y, Southon A, Aron A, Au-Yeung HY, Huang X, Lahiri DK, Wang F, Bush AI, Wulf GG, et al. Manganese causes neurotoxic iron accumulation via translational repression of Amyloid Precursor Protein (APP) and H-Ferritin. Journal of Neurochemistry. PMID 30152072 DOI: 10.1111/Jnc.14580 |
0.34 |
|
| 2018 |
Muñoz SS, Balez R, Castro Cabral-da-Silva ME, Berg T, Engel M, Bax M, Do-Ha D, Stevens CH, Greenough M, Bush A, Ooi L. Generation and characterization of human induced pluripotent stem cell lines from a familial Alzheimer's disease PSEN1 A246E patient and a non-demented family member bearing wild-type PSEN1. Stem Cell Research. 31: 227-230. PMID 30138848 DOI: 10.1016/J.Scr.2018.08.006 |
0.325 |
|
| 2018 |
Belaidi AA, Gunn AP, Wong BX, Ayton S, Appukuttan AT, Roberts BR, Duce JA, Bush AI. Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 30112699 DOI: 10.1007/S13311-018-0656-X |
0.352 |
|
| 2018 |
Furtado D, Björnmalm M, Ayton S, Bush AI, Kempe K, Caruso F. Overcoming the Blood-Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases. Advanced Materials (Deerfield Beach, Fla.). e1801362. PMID 30066406 DOI: 10.1002/Adma.201801362 |
0.301 |
|
| 2018 |
Beauchamp LC, Chan J, Hung LW, Padman BS, Vella LJ, Liu XM, Coleman B, Bush AI, Lazarou M, Hill AF, Jacobson L, Barnham KJ. Ablation of tau causes an olfactory deficit in a murine model of Parkinson's disease. Acta Neuropathologica Communications. 6: 57. PMID 29976255 DOI: 10.1186/S40478-018-0560-Y |
0.342 |
|
| 2018 |
Lane DJR, Ayton S, Bush AI. Iron and Alzheimer's Disease: An Update on Emerging Mechanisms. Journal of Alzheimer's Disease : Jad. PMID 29865061 DOI: 10.3233/Jad-179944 |
0.413 |
|
| 2018 |
Martins RN, Villemagne V, Sohrabi HR, Chatterjee P, Shah TM, Verdile G, Fraser P, Taddei K, Gupta VB, Rainey-Smith SR, Hone E, Pedrini S, Lim WL, Martins I, Frost S, ... ... Bush AI, et al. Alzheimer's Disease: A Journey from Amyloid Peptides and Oxidative Stress, to Biomarker Technologies and Disease Prevention Strategies-Gains from AIBL and DIAN Cohort Studies. Journal of Alzheimer's Disease : Jad. 62: 965-992. PMID 29562546 DOI: 10.3233/Jad-171145 |
0.744 |
|
| 2018 |
Adlard PA, Bush AI. Metals and Alzheimer's Disease: How Far Have We Come in the Clinic? Journal of Alzheimer's Disease : Jad. 62: 1369-1379. PMID 29562528 DOI: 10.3233/Jad-170662 |
0.374 |
|
| 2018 |
Takeda A, Tamano H, Hashimoto W, Kobuchi S, Suzuki H, Murakami T, Tempaku M, Koike Y, Adlard PA, Bush AI. Novel Defense by Metallothionein Induction Against Cognitive Decline: From Amyloid β-Induced Excess Znto Functional ZnDeficiency. Molecular Neurobiology. PMID 29460269 DOI: 10.1007/S12035-018-0948-5 |
0.364 |
|
| 2018 |
Porter T, Burnham SC, Doré V, Savage G, Bourgeat P, Begemann K, Milicic L, Ames D, Bush AI, Maruff P, Masters CL, Rowe CC, Rainey-Smith S, Martins RN, Groth D, et al. KIBRA is associated with accelerated cognitive decline and hippocampal atrophy in APOE ε4-positive cognitively normal adults with high Aβ-amyloid burden. Scientific Reports. 8: 2034. PMID 29391469 DOI: 10.1038/S41598-018-20513-Y |
0.713 |
|
| 2018 |
Moreau C, Duce JA, Rascol O, Devedjian JC, Berg D, Dexter D, Cabantchik ZI, Bush AI, Devos D. Iron as a therapeutic target for Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 29380903 DOI: 10.1002/Mds.27275 |
0.324 |
|
| 2018 |
Porter T, Villemagne VL, Savage G, Milicic L, Lim YY, Maruff P, Masters CL, Ames D, Bush AI, Martins RN, Rainey-Smith S, Rowe CC, Taddei K, Groth D, Verdile G, et al. Cognitive gene risk profile for the prediction of cognitive decline in presymptomatic Alzheimer’s disease Personalized Medicine in Psychiatry. 7: 14-20. DOI: 10.1016/J.Pmip.2018.03.001 |
0.609 |
|
| 2018 |
Ayton S, Bush AI. Iron and ferroptosis in the pathogenesis of Alzheimer´s disease Free Radical Biology and Medicine. 120: S8. DOI: 10.1016/J.Freeradbiomed.2018.04.037 |
0.478 |
|
| 2017 |
Doecke JD, Rembach A, Villemagne VL, Varghese S, Rainey-Smith S, Sarros S, Evered LA, Fowler CJ, Pertile KK, Rumble RL, Trounson B, Taddei K, Laws SM, Macaulay SL, Bush AI, et al. Concordance Between Cerebrospinal Fluid Biomarkers with Alzheimer's Disease Pathology Between Three Independent Assay Platforms. Journal of Alzheimer's Disease : Jad. PMID 29171991 DOI: 10.3233/Jad-170128 |
0.606 |
|
| 2017 |
Pedrini S, Gupta VB, Hone E, Doecke J, O'Bryant S, James I, Bush AI, Rowe CC, Villemagne VL, Ames D, Masters CL, Martins RN. A blood-based biomarker panel indicates IL-10 and IL-12/23p40 are jointly associated as predictors of β-amyloid load in an AD cohort. Scientific Reports. 7: 14057. PMID 29070909 DOI: 10.1038/S41598-017-14020-9 |
0.617 |
|
| 2017 |
Ayton S, James SA, Bush AI. Nanoscale Imaging Reveals Big Role for Iron in Alzheimer's Disease. Cell Chemical Biology. 24: 1192-1194. PMID 29053948 DOI: 10.1016/J.Chembiol.2017.10.002 |
0.391 |
|
| 2017 |
Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, et al. Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease. Cell. 171: 273-285. PMID 28985560 DOI: 10.1016/J.Cell.2017.09.021 |
0.32 |
|
| 2017 |
Ayton S, Diouf I, Bush AI. Evidence that iron accelerates Alzheimer's pathology: a CSF biomarker study. Journal of Neurology, Neurosurgery, and Psychiatry. 89: 456-460. PMID 28939683 DOI: 10.1136/Jnnp-2017-316551 |
0.405 |
|
| 2017 |
Ayton S, Fazlollahi A, Bourgeat P, Raniga P, Ng A, Lim YY, Diouf I, Farquharson S, Fripp J, Ames D, Doecke J, Desmond P, Ordidge R, Masters CL, Rowe CC, ... ... Bush AI, et al. Cerebral quantitative susceptibility mapping predicts amyloid-β-related cognitive decline. Brain : a Journal of Neurology. 140: 2112-2119. PMID 28899019 DOI: 10.1093/Brain/Awx137 |
0.475 |
|
| 2017 |
Goozee K, Chatterjee P, James I, Shen K, Sohrabi HR, Asih PR, Dave P, ManYan C, Taddei K, Ayton SJ, Garg ML, Kwok JB, Bush AI, Chung R, Magnussen JS, et al. Elevated plasma ferritin in elderly individuals with high neocortical amyloid-β load. Molecular Psychiatry. PMID 28696433 DOI: 10.1038/Mp.2017.146 |
0.554 |
|
| 2017 |
Finkelstein DI, Billings JL, Adlard PA, Ayton S, Sedjahtera A, Masters CL, Wilkins S, Shackleford DM, Charman SA, Bal W, Zawisza IA, Kurowska E, Gundlach AL, Ma S, Bush AI, et al. The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson's disease. Acta Neuropathologica Communications. 5: 53. PMID 28659169 DOI: 10.1186/S40478-017-0456-2 |
0.435 |
|
| 2017 |
Takeda A, Tamano H, Tempaku M, Sasaki M, Uematsu C, Sato S, Kanazawa H, Datki ZL, Adlard PA, Bush AI. Extracellular Zn(2+) is essential for amyloid β1-42-induced cognitive decline in the normal brain and its rescue. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28652412 DOI: 10.1523/Jneurosci.0954-17.2017 |
0.464 |
|
| 2017 |
Meng T, Cao Q, Lei P, Bush AI, Xiang Q, Su Z, He X, Rogers JT, Chiu IM, Zhang Q, Huang Y. Tat-haFGF14-154 Upregulates ADAM10 to Attenuate the Alzheimer Phenotype of APP/PS1 Mice through the PI3K-CREB-IRE1α/XBP1 Pathway. Molecular Therapy. Nucleic Acids. 7: 439-452. PMID 28624220 DOI: 10.1016/J.Omtn.2017.05.004 |
0.4 |
|
| 2017 |
Lupton MK, Benyamin B, Proitsi P, Nyholt DR, Ferreira MA, Montgomery GW, Heath AC, Madden PA, Medland SE, Gordon SD, Lovestone S, Tsolaki M, Kloszewska I, ... ... Bush AI, et al. No Genetic Overlap Between Circulating Iron Levels and Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 28582860 DOI: 10.3233/Jad-170027 |
0.396 |
|
| 2017 |
Berggren K, Agrawal S, Fox JA, Hildenbrand J, Nelson R, Bush AI, Fox JH. Amyloid Precursor Protein Haploinsufficiency Preferentially Mediates Brain Iron Accumulation in Mice Transgenic for The Huntington's Disease Mutation. Journal of Huntington's Disease. PMID 28550267 DOI: 10.3233/Jhd-170242 |
0.386 |
|
| 2017 |
Gupta VB, Hone E, Pedrini S, Doecke J, O'Bryant S, James I, Bush AI, Rowe CC, Villemagne VL, Ames D, Masters CL, Martins RN. Altered levels of blood proteins in Alzheimer's disease longitudinal study: Results from Australian Imaging Biomarkers Lifestyle Study of Ageing cohort. Alzheimer's & Dementia (Amsterdam, Netherlands). 8: 60-72. PMID 28508031 DOI: 10.1016/J.Dadm.2017.04.003 |
0.622 |
|
| 2017 |
Rita Cardoso B, Hare DJ, Lind M, McLean CA, Volitakis I, Laws SM, Masters CL, Bush AI, Roberts BR. The APOE ε4 allele is associated with lower selenium levels in the brain: implications in Alzheimer's disease. Acs Chemical Neuroscience. PMID 28453930 DOI: 10.1021/Acschemneuro.7B00014 |
0.535 |
|
| 2017 |
Mukherjee S, Kapp EA, Lothian A, Roberts AM, Vasilev Y, Boughton B, Barnham KJ, Kok WM, Hutton CA, Masters CL, Bush A, Beckman JS, Dey SG, Roberts BR. Characterization and identification of dityrosine cross-linked peptides using tandem mass spectrometry. Analytical Chemistry. PMID 28453255 DOI: 10.1021/Acs.Analchem.7B00941 |
0.639 |
|
| 2017 |
Cardoso BR, Hare DJ, Bush AI, Li QX, Fowler CJ, Masters CL, Martins RN, Ganio K, Lothian A, Mukherjee S, Kapp EA, Roberts BR. Selenium Levels in Serum, Red Blood Cells, and Cerebrospinal Fluid of Alzheimer's Disease Patients: A Report from the Australian Imaging, Biomarker & Lifestyle Flagship Study of Ageing (AIBL). Journal of Alzheimer's Disease : Jad. PMID 28222503 DOI: 10.3233/Jad-160622 |
0.714 |
|
| 2017 |
Guiney SJ, Adlard PA, Bush AI, Finkelstein DI, Ayton S. Ferroptosis and cell death mechanisms in Parkinson's disease. Neurochemistry International. PMID 28082232 DOI: 10.1016/J.Neuint.2017.01.004 |
0.307 |
|
| 2017 |
Betrie AH, Ayton S, Bush AI, Angus JA, Lei P, Wright CE. Evidence of a Cardiovascular Function for Microtubule-Associated Protein Tau. Journal of Alzheimer's Disease : Jad. PMID 28059795 DOI: 10.3233/Jad-161093 |
0.357 |
|
| 2017 |
Mckenzie-Nickson S, Bush AI, Barnham KJ. Bis(thiosemicarbazone) Metal Complexes as Therapeutics for Neurodegenerative Diseases. Current Topics in Medicinal Chemistry. 16: 3058-3068. PMID 26881708 DOI: 10.2174/1568026616666160216155746 |
0.367 |
|
| 2017 |
Belaidi AA, Ayton S, Bush AI. [P2-152]: IRON AND APOLIPOPROTEIN E LINK IN THE PATHOGENESIS OF ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P666-P666. DOI: 10.1016/J.Jalz.2017.06.802 |
0.394 |
|
| 2017 |
Fazlollahi A, Ayton S, Diouf I, Bourgeat P, Raniga P, Dore V, Ng A, Fripp J, Ames D, Masters CL, Rowe CC, Villemagne VL, Bush AI, Salvado O. QUANTITATIVE SUSCEPTIBILITY MAPPING OF THE HIPPOCAMPUS PREDICTS HIPPOCAMPAL ATROPHY IN Aβ+ ELDERLY CONTROLS AND ALZHEIMER’S DISEASE PATIENTS Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.460 |
0.456 |
|
| 2017 |
Pedrini S, Gupta VB, Hone E, Doecke JD, O'Bryant S, James I, Bush AI, Rowe CC, Villemagne VLL, Ames D, Masters CL, Martins RN. IL-10 AND IL-12/23P40 ARE JOINTLY ASSOCIATED AS PREDICTORS OF Aβ-AMYLOID LOAD IN A BROADER BLOOD-BASED BIOMARKER PANEL Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.2002 |
0.412 |
|
| 2017 |
Ashton NJ, Narvardo-Holgado AJ, Lynham S, Ward M, Gupta VB, Chatterjee P, Goozee K, Hone E, Pedrini S, Bush AI, Rowe CC, Villemagne VLL, Ames D, Masters CL, Aarsland D, et al. A mass spectrometry-based discovery and replication of a multi-analyte classifier for neocortical amyloid pathology Alzheimers & Dementia. 13: 1033. DOI: 10.1016/J.Jalz.2017.06.1456 |
0.54 |
|
| 2017 |
Wong BX, Tsatsanis A, Lam LQ, Ayton S, Gunn AP, Devos D, Bush AI, Duce JA. The Influence Of Amyloid-B Precursor Protein Proteolytic Processing On Neuronal Iron Homeostasis Alzheimers & Dementia. 13: 993. DOI: 10.1016/J.Jalz.2017.06.1365 |
0.318 |
|
| 2016 |
Lam LQ, Wong BX, Frugier T, Li QX, Collins SJ, Bush AI, Crack PJ, Duce JA. Oxidation of iron under physiologically relevant conditions in biological fluids from healthy and Alzheimer's disease subjects. Acs Chemical Neuroscience. PMID 28029772 DOI: 10.1021/Acschemneuro.6B00411 |
0.371 |
|
| 2016 |
Roberts BR, Doecke JD, Rembach A, Yévenes LF, Fowler CJ, McLean CA, Lind M, Volitakis I, Masters CL, Bush AI, Hare DJ. Rubidium and potassium levels are altered in Alzheimer's disease brain and blood but not in cerebrospinal fluid. Acta Neuropathologica Communications. 4: 119. PMID 27842602 DOI: 10.1186/S40478-016-0390-8 |
0.528 |
|
| 2016 |
Mahoney-Sanchez L, Belaidi AA, Bush AI, Ayton S. The Complex Role of Apolipoprotein E in Alzheimer's Disease: an Overview and Update. Journal of Molecular Neuroscience : Mn. PMID 27647307 DOI: 10.1007/S12031-016-0839-Z |
0.456 |
|
| 2016 |
Burnham SC, Rowe CC, Baker D, Bush AI, Doecke JD, Faux NG, Laws SM, Martins RN, Maruff P, Macaulay SL, Rainey-Smith S, Savage G, Ames D, Masters CL, Wilson W, et al. Predicting Alzheimer disease from a blood-based biomarker profile: A 54-month follow-up. Neurology. PMID 27534714 DOI: 10.1212/Wnl.0000000000003094 |
0.609 |
|
| 2016 |
Abramovitch-Dahan C, Asraf H, Bogdanovic M, Sekler I, Bush AI, Hershfinkel M. Amyloid β attenuates metabotropic zinc sensing receptor, mZnR/GPR39, dependent Ca(2+) , ERK1/2 and Clusterin signaling in neurons. Journal of Neurochemistry. PMID 27501363 DOI: 10.1111/Jnc.13760 |
0.382 |
|
| 2016 |
Tamano H, Ide K, Adlard PA, Bush AI, Takeda A. Involvement of hippocampal excitability in amyloid β-induced behavioral and psychological symptoms of dementia. The Journal of Toxicological Sciences. 41: 449-57. PMID 27432231 DOI: 10.2131/Jts.41.449 |
0.354 |
|
| 2016 |
Lei P, Ayton S, Appukuttan AT, Moon S, Duce JA, Volitakis I, Cherny R, Wood SJ, Greenough M, Berger G, Pantelis C, McGorry P, Yung A, Finkelstein DI, Bush AI. Lithium suppression of tau induces brain iron accumulation and neurodegeneration. Molecular Psychiatry. PMID 27400857 DOI: 10.1038/Mp.2016.96 |
0.375 |
|
| 2016 |
Greenough MA, Ramírez Munoz A, Bush AI, Opazo CM. Metallo-pathways to Alzheimer's disease: lessons from genetic disorders of copper trafficking. Metallomics : Integrated Biometal Science. PMID 27397642 DOI: 10.1039/C6Mt00095A |
0.442 |
|
| 2016 |
Gupta VB, Doecke JD, Hone E, Pedrini S, Laws SM, Thambisetty M, Bush AI, Rowe CC, Villemagne VL, Ames D, Masters CL, Macaulay SL, Rembach A, Rainey-Smith SR, Martins RN, et al. Plasma apolipoprotein J as a potential biomarker for Alzheimer's disease: Australian Imaging, Biomarkers and Lifestyle study of aging. Alzheimer's & Dementia (Amsterdam, Netherlands). 3: 18-26. PMID 27239546 DOI: 10.1016/J.Dadm.2015.12.001 |
0.622 |
|
| 2016 |
Hare DJ, Raven EP, Roberts BR, Bogeski M, Portbury SD, McLean CA, Masters CL, Connor JR, Bush AI, Crouch PJ, Doble PA. Laser ablation-inductively coupled plasma-mass spectrometry imaging of white and grey matter iron distribution in Alzheimer's disease frontal cortex. Neuroimage. PMID 27233149 DOI: 10.1016/J.Neuroimage.2016.05.057 |
0.473 |
|
| 2016 |
Yang PH, Zhu JX, Huang YD, Zhang XY, Lei P, Bush AI, Xiang Q, Su ZJ, Zhang QH. Human Basic Fibroblast Growth Factor Inhibits Tau Phosphorylation via the PI3K/Akt-GSK3β Signaling Pathway in a 6-Hydroxydopamine-Induced Model of Parkinson's Disease. Neuro-Degenerative Diseases. 16: 357-369. PMID 27228974 DOI: 10.1159/000445871 |
0.334 |
|
| 2016 |
Hare DJ, Faux NG, Roberts BR, Volitakis I, Martins RN, Bush AI. Lead and manganese levels in serum and erythrocytes in Alzheimer's disease and mild cognitive impairment: results from the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing. Metallomics : Integrated Biometal Science. PMID 26962965 DOI: 10.1039/C6Mt00019C |
0.568 |
|
| 2016 |
Xu H, Perreau VM, Dent KA, Bush AI, Finkelstein DI, Adlard PA. Iron Regulates Apolipoprotein E Expression and Secretion in Neurons and Astrocytes. Journal of Alzheimer's Disease : Jad. PMID 26890748 DOI: 10.3233/Jad-150797 |
0.418 |
|
| 2016 |
Manso Y, Comes G, López-Ramos JC, Belfiore M, Molinero A, Giralt M, Carrasco J, Adlard PA, Bush AI, Delgado-García JM, Hidalgo J. Overexpression of Metallothionein-1 Modulates the Phenotype of the Tg2576 Mouse Model of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 26836194 DOI: 10.3233/Jad-151025 |
0.406 |
|
| 2016 |
Morris MC, Bush AI, Ayton S, Brockman J, Wang Y, Bennett DA, Schneider JA. P3-312: Brain Iron Levels Associated With Increased Alzheimer's Disease Neuropathology Alzheimer's & Dementia. 12: P962-P962. DOI: 10.1016/J.Jalz.2016.06.1976 |
0.409 |
|
| 2016 |
Fazlollahi A, Salvado O, Ayton S, Bourgeat P, Fripp J, Ng A, Raniga P, Dore V, Ames D, Masters CL, Rowe CC, Villemagne VL, Bush AI. Iron And Amyloid Depositions Are Positively Related In Non-Demented Individuals Alzheimers & Dementia. 12: 542. DOI: 10.1016/J.Jalz.2016.06.1062 |
0.342 |
|
| 2016 |
Gupta VB, Doecke JD, Hone E, Pedrini S, Laws SM, Thambisetty M, Bush AI, Rowe CC, Villemagne VL, Ames D, Masters CL, Macaulay SL, Rembach A, Rainey-Smith SR, Martins RN. Plasma apolipoprotein J as a potential biomarker for Alzheimer's disease: Australian Imaging, Biomarkers and Lifestyle study of aging Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 3: 18-26. DOI: 10.1016/j.dadm.2015.12.001 |
0.526 |
|
| 2015 |
Paul B, Hare DJ, Bishop DP, Paton C, Nguyen VT, Cole N, Niedwiecki MM, Andreozzi E, Vais A, Billings JL, Bray L, Bush AI, McColl G, Roberts BR, Adlard PA, et al. Visualising mouse neuroanatomy and function by metal distribution using laser ablation-inductively coupled plasma-mass spectrometry imaging. Chemical Science. 6: 5383-5393. PMID 29449912 DOI: 10.1039/C5Sc02231B |
0.301 |
|
| 2015 |
Gunn AP, Wong BX, Johanssen T, Griffith JC, Masters CL, Bush AI, Barnham KJ, Duce JA, Cherny RA. Amyloid-Beta Peptide Aβ3pE-42 Induces Lipid Peroxidation, Membrane Permeabilization and Calcium-Influx in Neurons. The Journal of Biological Chemistry. PMID 26697885 DOI: 10.1074/Jbc.M115.655183 |
0.532 |
|
| 2015 |
Belaidi AA, Bush AI. Iron neurochemistry in Alzheimer's disease and Parkinson's disease: targets for therapeutics. Journal of Neurochemistry. PMID 26545340 DOI: 10.1111/Jnc.13425 |
0.394 |
|
| 2015 |
Finkelstein DI, Hare DJ, Billings JL, Sedjahtera A, Nurjono M, Arthofer E, George S, Culvenor JG, Bush AI, Adlard PA. Clioquinol Improves Cognitive, Motor Function, and Microanatomy of the Alpha-Synuclein hA53T Transgenic Mice. Acs Chemical Neuroscience. PMID 26481462 DOI: 10.1021/Acschemneuro.5B00253 |
0.329 |
|
| 2015 |
Liang SH, Southon AG, Fraser BH, Krause-Heuer AM, Zhang B, Shoup TM, Lewis R, Volitakis I, Han Y, Greguric I, Bush AI, Vasdev N. Novel Fluorinated 8-Hydroxyquinoline Based Metal Ionophores for Exploring the Metal Hypothesis of Alzheimer's Disease. Acs Medicinal Chemistry Letters. 6: 1025-9. PMID 26396692 DOI: 10.1021/Acsmedchemlett.5B00281 |
0.421 |
|
| 2015 |
Li X, Lei P, Tuo Q, Ayton S, Li QX, Moon S, Volitakis I, Liu R, Masters CL, Finkelstein DI, Bush AI. Enduring Elevations of Hippocampal Amyloid Precursor Protein and Iron Are Features of β-Amyloid Toxicity and Are Mediated by Tau. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 862-73. PMID 26260389 DOI: 10.1007/S13311-015-0378-2 |
0.568 |
|
| 2015 |
Xu H, Gupta VB, Martins IJ, Martins RN, Fowler CJ, Bush AI, Finkelstein DI, Adlard PA. Zinc affects the proteolytic stability of Apolipoprotein E in an isoform-dependent way. Neurobiology of Disease. PMID 26117305 DOI: 10.1016/J.Nbd.2015.06.016 |
0.562 |
|
| 2015 |
Cardoso BR, Roberts BR, Bush AI, Hare DJ. Selenium, selenoproteins and neurodegenerative diseases. Metallomics : Integrated Biometal Science. PMID 25996565 DOI: 10.1039/C5Mt00075K |
0.353 |
|
| 2015 |
Ayton S, Faux NG, Bush AI. Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE. Nature Communications. 6: 6760. PMID 25988319 DOI: 10.1038/ncomms7760 |
0.342 |
|
| 2015 |
Chan J, Jones NC, Bush AI, O'Brien TJ, Kwan P. A mouse model of Alzheimer's disease displays increased susceptibility to kindling and seizure-associated death. Epilepsia. 56: e73-7. PMID 25879152 DOI: 10.1111/Epi.12993 |
0.338 |
|
| 2015 |
Gupta VB, Wilson AC, Burnham S, Hone E, Pedrini S, Laws SM, Lim WL, Rembach A, Rainey-Smith S, Ames D, Cobiac L, Macaulay SL, Masters CL, Rowe CC, Bush AI, et al. Follow-up plasma apolipoprotein E levels in the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing (AIBL) cohort. Alzheimer's Research & Therapy. 7: 16. PMID 25859282 DOI: 10.1186/S13195-015-0105-6 |
0.699 |
|
| 2015 |
Lei P, Ayton S, Appukuttan AT, Volitakis I, Adlard PA, Finkelstein DI, Bush AI. Clioquinol rescues Parkinsonism and dementia phenotypes of the tau knockout mouse. Neurobiology of Disease. PMID 25796563 DOI: 10.1016/J.Nbd.2015.03.015 |
0.408 |
|
| 2015 |
Ayton S, Lei P, Hare DJ, Duce JA, George JL, Adlard PA, McLean C, Rogers JT, Cherny RA, Finkelstein DI, Bush AI. Parkinson's disease iron deposition caused by nitric oxide-induced loss of β-amyloid precursor protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 3591-7. PMID 25716857 DOI: 10.1523/Jneurosci.3439-14.2015 |
0.35 |
|
| 2015 |
Berggren KL, Chen J, Fox J, Miller J, Dodds L, Dugas B, Vargas L, Lothian A, McAllum E, Volitakis I, Roberts B, Bush AI, Fox JH. Neonatal iron supplementation potentiates oxidative stress, energetic dysfunction and neurodegeneration in the R6/2 mouse model of Huntington's disease. Redox Biology. 4: 363-74. PMID 25703232 DOI: 10.1016/J.Redox.2015.02.002 |
0.32 |
|
| 2015 |
Hare DJ, Doecke JD, Faux NG, Rembach A, Volitakis I, Fowler CJ, Grimm R, Doble PA, Cherny RA, Masters CL, Bush AI, Roberts BR. Decreased plasma iron in Alzheimer's disease is due to transferrin desaturation. Acs Chemical Neuroscience. 6: 398-402. PMID 25588002 DOI: 10.1021/Cn5003557 |
0.511 |
|
| 2015 |
Roberts BR, Hare DJ, McLean CA, Conquest A, Lind M, Li QX, Bush AI, Masters CL, Morganti-Kossmann MC, Frugier T. Traumatic brain injury induces elevation of Co in the human brain. Metallomics : Integrated Biometal Science. 7: 66-70. PMID 25424382 DOI: 10.1039/C4Mt00258J |
0.408 |
|
| 2015 |
Ayton S, Lei P, Bush AI. Biometals and their therapeutic implications in Alzheimer's disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 109-20. PMID 25354461 DOI: 10.1007/S13311-014-0312-Z |
0.43 |
|
| 2015 |
Robb E, Perez K, Hung LW, Masters CL, Barnham KJ, Cherny RA, Bush AI, Adlard PA, Finkelstein DI. High order W02-reactive stable oligomers of amyloid-β are produced in vivo and in vitro via dialysis and filtration of synthetic amyloid-β monomer. Journal of Alzheimer's Disease : Jad. 44: 69-78. PMID 25182735 DOI: 10.3233/Jad-132024 |
0.527 |
|
| 2015 |
Fazlollahi A, Calamante F, Liang X, Good NM, Bush A, Ames D, Masters CL, Meriaudeau F, Connelly A, Rowe CC, Villemagne VL, Salvado O, Bourgeat P. Decreases in cerebral blood flow are associated with Aβ status in preclinical Alzheimer’s disease Alzheimers & Dementia. 11: 886. DOI: 10.1016/J.Jalz.2015.08.095 |
0.333 |
|
| 2015 |
Lupton MK, Benyamin B, Wright M, Powell JF, Nyholt D, Ferreira M, Bush A, Heath A, Madden P, Martin N, Montgomery G, Whitfield J. Assessment of genetic overlap between serum iron levels and risk of Alzheimer's disease Alzheimers & Dementia. 11: 623. DOI: 10.1016/J.Jalz.2015.06.876 |
0.366 |
|
| 2015 |
Li X, Lei P, Tuo Q, Ayton S, Li QX, Moon S, Volitakis I, Liu R, Masters CL, Finkelstein DI, Bush AI. Enduring Elevations of Hippocampal Amyloid Precursor Protein and Iron Are Features of β-Amyloid Toxicity and Are Mediated by Tau Neurotherapeutics. DOI: 10.1007/s13311-015-0378-2 |
0.428 |
|
| 2014 |
Adlard PA, Parncutt J, Lal V, James S, Hare D, Doble P, Finkelstein DI, Bush AI. Metal chaperones prevent zinc-mediated cognitive decline. Neurobiology of Disease. PMID 25549871 DOI: 10.1016/J.Nbd.2014.12.012 |
0.371 |
|
| 2014 |
Takeda A, Nakamura M, Fujii H, Uematsu C, Minamino T, Adlard PA, Bush AI, Tamano H. Amyloid β-mediated Zn2+ influx into dentate granule cells transiently induces a short-term cognitive deficit. Plos One. 9: e115923. PMID 25536033 DOI: 10.1371/Journal.Pone.0115923 |
0.388 |
|
| 2014 |
Castro PA, Ramirez A, Sepúlveda FJ, Peters C, Fierro H, Waldron J, Luza S, Fuentealba J, Muñoz FJ, De Ferrari GV, Bush AI, Aguayo LG, Opazo CM. Copper-uptake is critical for the down regulation of synapsin and dynamin induced by neocuproine: modulation of synaptic activity in hippocampal neurons. Frontiers in Aging Neuroscience. 6: 319. PMID 25520655 DOI: 10.3389/Fnagi.2014.00319 |
0.334 |
|
| 2014 |
Wong BX, Tsatsanis A, Lim LQ, Adlard PA, Bush AI, Duce JA. β-Amyloid precursor protein does not possess ferroxidase activity but does stabilize the cell surface ferrous iron exporter ferroportin. Plos One. 9: e114174. PMID 25464026 DOI: 10.1371/Journal.Pone.0114174 |
0.324 |
|
| 2014 |
Adlard PA, Tran BA, Finkelstein DI, Desmond PM, Johnston LA, Bush AI, Egan GF. A review of β-amyloid neuroimaging in Alzheimer's disease. Frontiers in Neuroscience. 8: 327. PMID 25400539 DOI: 10.3389/Fnins.2014.00327 |
0.456 |
|
| 2014 |
Brown BM, Bourgeat P, Peiffer JJ, Burnham S, Laws SM, Rainey-Smith SR, Bartrés-Faz D, Villemagne VL, Taddei K, Rembach A, Bush A, Ellis KA, Macaulay SL, Rowe CC, Ames D, et al. Influence of BDNF Val66Met on the relationship between physical activity and brain volume. Neurology. 83: 1345-52. PMID 25186863 DOI: 10.1212/Wnl.0000000000000867 |
0.488 |
|
| 2014 |
Adlard PA, Li QX, McLean C, Masters CL, Bush AI, Fodero-Tavoletti M, Villemagne V, Barnham KJ. β-amyloid in biological samples: not all Aβ detection methods are created equal. Frontiers in Aging Neuroscience. 6: 203. PMID 25165449 DOI: 10.3389/Fnagi.2014.00203 |
0.552 |
|
| 2014 |
Yu M, Ryan TM, Ellis S, Bush AI, Triccas JA, Rutledge PJ, Todd MH. Neuroprotective peptide-macrocycle conjugates reveal complex structure-activity relationships in their interactions with amyloid β. Metallomics : Integrated Biometal Science. 6: 1931-40. PMID 25132118 DOI: 10.1039/C4Mt00122B |
0.4 |
|
| 2014 |
Lei P, Ayton S, Moon S, Zhang Q, Volitakis I, Finkelstein DI, Bush AI. Motor and cognitive deficits in aged tau knockout mice in two background strains. Molecular Neurodegeneration. 9: 29. PMID 25124182 DOI: 10.1186/1750-1326-9-29 |
0.333 |
|
| 2014 |
Barnham KJ, Bush AI. Biological metals and metal-targeting compounds in major neurodegenerative diseases. Chemical Society Reviews. 43: 6727-49. PMID 25099276 DOI: 10.1039/C4Cs00138A |
0.385 |
|
| 2014 |
Ciccotosto GD, James SA, Altissimo M, Paterson D, Vogt S, Lai B, de Jonge MD, Howard DL, Bush AI, Cappai R. Quantitation and localization of intracellular redox active metals by X-ray fluorescence microscopy in cortical neurons derived from APP and APLP2 knockout tissue. Metallomics : Integrated Biometal Science. 6: 1894-904. PMID 25098278 DOI: 10.1039/C4Mt00176A |
0.358 |
|
| 2014 |
Opazo CM, Greenough MA, Bush AI. Copper: from neurotransmission to neuroproteostasis. Frontiers in Aging Neuroscience. 6: 143. PMID 25071552 DOI: 10.3389/Fnagi.2014.00143 |
0.347 |
|
| 2014 |
Lu Z, Marks E, Chen J, Moline J, Barrows L, Raisbeck M, Volitakis I, Cherny RA, Chopra V, Bush AI, Hersch S, Fox JH. Altered selenium status in Huntington's disease: neuroprotection by selenite in the N171-82Q mouse model. Neurobiology of Disease. 71: 34-42. PMID 25014023 DOI: 10.1016/J.Nbd.2014.06.022 |
0.325 |
|
| 2014 |
Ayton S, Lei P, Adlard PA, Volitakis I, Cherny RA, Bush AI, Finkelstein DI. Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson's disease. Molecular Neurodegeneration. 9: 27. PMID 25011704 DOI: 10.1186/1750-1326-9-27 |
0.3 |
|
| 2014 |
Barnard ND, Bush AI, Ceccarelli A, Cooper J, de Jager CA, Erickson KI, Fraser G, Kesler S, Levin SM, Lucey B, Morris MC, Squitti R. Dietary and lifestyle guidelines for the prevention of Alzheimer's disease. Neurobiology of Aging. 35: S74-8. PMID 24913896 DOI: 10.1016/J.Neurobiolaging.2014.03.033 |
0.36 |
|
| 2014 |
Rembach A, Watt AD, Wilson WJ, Rainey-Smith S, Ellis KA, Rowe CC, Villemagne VL, Macaulay SL, Bush AI, Martins RN, Ames D, Masters CL, Doecke JD. An increased neutrophil-lymphocyte ratio in Alzheimer's disease is a function of age and is weakly correlated with neocortical amyloid accumulation. Journal of Neuroimmunology. 273: 65-71. PMID 24907904 DOI: 10.1016/J.Jneuroim.2014.05.005 |
0.614 |
|
| 2014 |
Roberts BR, Lim NK, McAllum EJ, Donnelly PS, Hare DJ, Doble PA, Turner BJ, Price KA, Lim SC, Paterson BM, Hickey JL, Rhoads TW, Williams JR, Kanninen KM, Hung LW, ... ... Bush AI, et al. Oral treatment with Cu(II)(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8021-31. PMID 24899723 DOI: 10.1523/Jneurosci.4196-13.2014 |
0.418 |
|
| 2014 |
Wong BX, Hung YH, Bush AI, Duce JA. Metals and cholesterol: two sides of the same coin in Alzheimer's disease pathology. Frontiers in Aging Neuroscience. 6: 91. PMID 24860500 DOI: 10.3389/Fnagi.2014.00091 |
0.481 |
|
| 2014 |
Rembach A, Hare DJ, Doecke JD, Burnham SC, Volitakis I, Fowler CJ, Cherny RA, McLean C, Grimm R, Martins R, Ames D, Masters CL, Bush AI, Roberts BR. Decreased serum zinc is an effect of ageing and not Alzheimer's disease. Metallomics : Integrated Biometal Science. 6: 1216-9. PMID 24676028 DOI: 10.1039/C4Mt00060A |
0.62 |
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| 2014 |
Acevedo KM, Opazo CM, Norrish D, Challis LM, Li QX, White AR, Bush AI, Camakaris J. Phosphorylation of amyloid precursor protein at threonine 668 is essential for its copper-responsive trafficking in SH-SY5Y neuroblastoma cells. The Journal of Biological Chemistry. 289: 11007-19. PMID 24610780 DOI: 10.1074/Jbc.M113.538710 |
0.327 |
|
| 2014 |
Ayton S, Zhang M, Roberts BR, Lam LQ, Lind M, McLean C, Bush AI, Frugier T, Crack PJ, Duce JA. Ceruloplasmin and β-amyloid precursor protein confer neuroprotection in traumatic brain injury and lower neuronal iron. Free Radical Biology & Medicine. 69: 331-7. PMID 24509156 DOI: 10.1016/J.Freeradbiomed.2014.01.041 |
0.323 |
|
| 2014 |
Lim YY, Villemagne VL, Laws SM, Ames D, Pietrzak RH, Ellis KA, Harrington K, Bourgeat P, Bush AI, Martins RN, Masters CL, Rowe CC, Maruff P. Effect of BDNF Val66Met on memory decline and hippocampal atrophy in prodromal Alzheimer's disease: a preliminary study. Plos One. 9: e86498. PMID 24475133 DOI: 10.1371/Journal.Pone.0086498 |
0.579 |
|
| 2014 |
Faux NG, Rembach A, Wiley J, Ellis KA, Ames D, Fowler CJ, Martins RN, Pertile KK, Rumble RL, Trounson B, Masters CL, Bush AI. An anemia of Alzheimer's disease. Molecular Psychiatry. 19: 1227-34. PMID 24419041 DOI: 10.1038/Mp.2013.178 |
0.625 |
|
| 2014 |
Rembach A, Watt AD, Wilson WJ, Villemagne VL, Burnham SC, Ellis KA, Maruff P, Ames D, Rowe CC, Macaulay SL, Bush AI, Martins RN, Masters CL, Doecke JD. Plasma amyloid-β levels are significantly associated with a transition toward Alzheimer's disease as measured by cognitive decline and change in neocortical amyloid burden. Journal of Alzheimer's Disease : Jad. 40: 95-104. PMID 24334723 DOI: 10.3233/Jad-131802 |
0.593 |
|
| 2014 |
Ellis KA, Szoeke C, Bush AI, Darby D, Graham PL, Lautenschlager NT, Macaulay SL, Martins RN, Maruff P, Masters CL, McBride SJ, Pike KE, Rainey-Smith SR, Rembach A, Robertson J, et al. Rates of diagnostic transition and cognitive change at 18-month follow-up among 1,112 participants in the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing (AIBL). International Psychogeriatrics / Ipa. 26: 543-54. PMID 24252258 DOI: 10.1017/S1041610213001956 |
0.576 |
|
| 2014 |
Moore EM, Ames D, Mander AG, Carne RP, Brodaty H, Woodward MC, Boundy K, Ellis KA, Bush AI, Faux NG, Martins RN, Masters CL, Rowe CC, Szoeke C, Watters DA. Among vitamin B12 deficient older people, high folate levels are associated with worse cognitive function: combined data from three cohorts. Journal of Alzheimer's Disease : Jad. 39: 661-8. PMID 24246419 DOI: 10.3233/Jad-131265 |
0.519 |
|
| 2014 |
Squitti R, Simonelli I, Ventriglia M, Siotto M, Pasqualetti P, Rembach A, Doecke J, Bush AI. Meta-analysis of serum non-ceruloplasmin copper in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 38: 809-22. PMID 24072069 DOI: 10.3233/Jad-131247 |
0.366 |
|
| 2014 |
Burnham SC, Faux NG, Wilson W, Laws SM, Ames D, Bedo J, Bush AI, Doecke JD, Ellis KA, Head R, Jones G, Kiiveri H, Martins RN, Rembach A, Rowe CC, et al. A blood-based predictor for neocortical Aβ burden in Alzheimer's disease: results from the AIBL study. Molecular Psychiatry. 19: 519-26. PMID 23628985 DOI: 10.1038/Mp.2013.40 |
0.579 |
|
| 2014 |
Rembach A, Faux NG, Watt AD, Pertile KK, Rumble RL, Trounson BO, Fowler CJ, Roberts BR, Perez KA, Li QX, Laws SM, Taddei K, Rainey-Smith S, Robertson JS, Vandijck M, ... ... Bush AI, et al. Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 53-61. PMID 23491263 DOI: 10.1016/J.Jalz.2012.12.006 |
0.613 |
|
| 2014 |
Verdile G, Laws SM, Henley D, Ames D, Bush AI, Ellis KA, Faux NG, Gupta VB, Li QX, Masters CL, Pike KE, Rowe CC, Szoeke C, Taddei K, Villemagne VL, et al. Associations between gonadotropins, testosterone and β amyloid in men at risk of Alzheimer's disease. Molecular Psychiatry. 19: 69-75. PMID 23089633 DOI: 10.1038/Mp.2012.147 |
0.734 |
|
| 2014 |
Hare DJ, Lei P, Ayton S, Roberts BR, Grimm R, George JL, Bishop DP, Beavis AD, Donovan SJ, McColl G, Volitakis I, Masters CL, Adlard PA, Cherny RA, Bush AI, et al. An iron-dopamine index predicts risk of parkinsonian neurodegeneration in the substantia nigra pars compacta Chemical Science. 5: 2160-2169. DOI: 10.1039/C3Sc53461H |
0.426 |
|
| 2014 |
Hare DJ, George JL, Bray L, Volitakis I, Vais A, Ryan TM, Cherny RA, Bush AI, Masters CL, Adlard PA, Doble PA, Finkelstein DI. The effect of paraformaldehyde fixation and sucrose cryoprotection on metal concentration in murine neurological tissue Journal of Analytical Atomic Spectrometry. 29: 565-570. DOI: 10.1039/C3Ja50281C |
0.41 |
|
| 2014 |
Xu H, Finkelstein D, Bush AI, Adlard P. P4-250: ZINC AFFECTS THE STABILITY OF APOLIPOPROTEIN E IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 10: P877-P877. DOI: 10.1016/J.Jalz.2014.07.021 |
0.391 |
|
| 2014 |
Yevenes Ugarte LF, Fowler CJ, Hung YH, Finkelstein DI, Adlard PA, Masters CL, Bush AI. P2-130: PROTEIN AND METAL ALTERATIONS IN PLATELETS OF ALZHEIMER'S DISEASE PATIENTS Alzheimer's & Dementia. 10: P518-P518. DOI: 10.1016/J.Jalz.2014.05.805 |
0.394 |
|
| 2014 |
Fowler CJ, Yevenes LF, Rembach A, Faux NG, Trounson B, Pertile K, Rumble R, Ellis KA, Ames D, Bush AI, Martins R, Masters CL. P3-114: ELEVATED BLOOD HDL AND HDL-ASSOCIATED LIPOPROTEINS IN HEALTHY CONTROLS WHO RAPIDLY CONVERT TO ALZHEIMER'S DISEASE IN THE AIBL COHORT Alzheimer's & Dementia. 10: P670-P670. DOI: 10.1016/J.Jalz.2014.05.1203 |
0.568 |
|
| 2014 |
Wilson AC, Garin S, Porter TLS, Verdile G, Groth DM, Villemagne VL, Ames D, Bush AI, Ellis KA, Macaulay L, Masters CL, Rainey-Smith SR, Rembach A, Rowe C, Taddei K, et al. Genetic Analysis Of The Steroidogenesis Pathway: Associations With Alzheimer'S Disease Risk And Related Phenotypes Alzheimers & Dementia. 10: 667. DOI: 10.1016/J.Jalz.2014.05.1195 |
0.679 |
|
| 2014 |
Laws SM, Porter T, Creegan R, Lim WLF, Verdile G, Groth DM, Villemagne V, Wilson AC, Ames D, Bush AI, Ellis KA, Macaulay L, Masters CL, Rainey-Smith SL, Rembach A, et al. Genetic Variation Within Genes Of The Sphingolipid Metabolism Pathway And Their Association With Alzheimer'S Disease Risk And Related Phenotypes Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.05.1110 |
0.652 |
|
| 2013 |
Maruff P, Lim YY, Darby D, Ellis KA, Pietrzak RH, Snyder PJ, Bush AI, Szoeke C, Schembri A, Ames D, Masters CL. Clinical utility of the cogstate brief battery in identifying cognitive impairment in mild cognitive impairment and Alzheimer's disease. Bmc Psychology. 1: 30. PMID 25566378 DOI: 10.1186/2050-7283-1-30 |
0.481 |
|
| 2013 |
Squitti R, Hoogenraad T, Brewer G, Bush AI, Polimanti R. Copper status in Alzheimer's disease and other neurodegenerative disorders 2013. International Journal of Alzheimer's Disease. 2013: 838274. PMID 24455406 DOI: 10.1155/2013/838274 |
0.45 |
|
| 2013 |
Rembach A, Hare DJ, Lind M, Fowler CJ, Cherny RA, McLean C, Bush AI, Masters CL, Roberts BR. Decreased copper in Alzheimer's disease brain is predominantly in the soluble extractable fraction. International Journal of Alzheimer's Disease. 2013: 623241. PMID 24228186 DOI: 10.1155/2013/623241 |
0.535 |
|
| 2013 |
Chen J, Marks E, Lai B, Zhang Z, Duce JA, Lam LQ, Volitakis I, Bush AI, Hersch S, Fox JH. Iron accumulates in Huntington's disease neurons: protection by deferoxamine. Plos One. 8: e77023. PMID 24146952 DOI: 10.1371/Journal.Pone.0077023 |
0.315 |
|
| 2013 |
Hare DJ, Grubman A, Ryan TM, Lothian A, Liddell JR, Grimm R, Matsuda T, Doble PA, Cherny RA, Bush AI, White AR, Masters CL, Roberts BR. Profiling the iron, copper and zinc content in primary neuron and astrocyte cultures by rapid online quantitative size exclusion chromatography-inductively coupled plasma-mass spectrometry. Metallomics : Integrated Biometal Science. 5: 1656-62. PMID 24132241 DOI: 10.1039/C3Mt00227F |
0.411 |
|
| 2013 |
Moore EM, Mander AG, Ames D, Kotowicz MA, Carne RP, Brodaty H, Woodward M, Boundy K, Ellis KA, Bush AI, Faux NG, Martins R, Szoeke C, Rowe C, Watters DA, et al. Increased risk of cognitive impairment in patients with diabetes is associated with metformin. Diabetes Care. 36: 2981-7. PMID 24009301 DOI: 10.2337/Dc13-0229 |
0.432 |
|
| 2013 |
Lim YY, Villemagne VL, Laws SM, Ames D, Pietrzak RH, Ellis KA, Harrington KD, Bourgeat P, Salvado O, Darby D, Snyder PJ, Bush AI, Martins RN, Masters CL, Rowe CC, et al. BDNF Val66Met, Aβ amyloid, and cognitive decline in preclinical Alzheimer's disease. Neurobiology of Aging. 34: 2457-64. PMID 23769397 DOI: 10.1016/J.Neurobiolaging.2013.05.006 |
0.598 |
|
| 2013 |
Hung YH, Bush AI, La Fontaine S. Links between copper and cholesterol in Alzheimer's disease. Frontiers in Physiology. 4: 111. PMID 23720634 DOI: 10.3389/Fphys.2013.00111 |
0.459 |
|
| 2013 |
Lim YY, Ellis KA, Harrington K, Kamer A, Pietrzak RH, Bush AI, Darby D, Martins RN, Masters CL, Rowe CC, Savage G, Szoeke C, Villemagne VL, Ames D, Maruff P. Cognitive consequences of high Aβ amyloid in mild cognitive impairment and healthy older adults: implications for early detection of Alzheimer's disease. Neuropsychology. 27: 322-32. PMID 23688214 DOI: 10.1037/A0032321 |
0.586 |
|
| 2013 |
Southon A, Greenough MA, Ganio G, Bush AI, Burke R, Camakaris J. Presenilin promotes dietary copper uptake. Plos One. 8: e62811. PMID 23667524 DOI: 10.1371/Journal.Pone.0062811 |
0.352 |
|
| 2013 |
Lim YY, Jaeger J, Harrington K, Ashwood T, Ellis KA, Stöffler A, Szoeke C, Lachovitzki R, Martins RN, Villemagne VL, Bush A, Masters CL, Rowe CC, Ames D, Darby D, et al. Three-month stability of the CogState brief battery in healthy older adults, mild cognitive impairment, and Alzheimer's disease: results from the Australian Imaging, Biomarkers, and Lifestyle-rate of change substudy (AIBL-ROCS). Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists. 28: 320-30. PMID 23552802 DOI: 10.1093/Arclin/Act021 |
0.567 |
|
| 2013 |
Ellis KA, Lim YY, Harrington K, Ames D, Bush AI, Darby D, Martins RN, Masters CL, Rowe CC, Savage G, Szoeke C, Villemagne VL, Maruff P. Decline in cognitive function over 18 months in healthy older adults with high amyloid-β. Journal of Alzheimer's Disease : Jad. 34: 861-71. PMID 23302660 DOI: 10.3233/Jad-122170 |
0.52 |
|
| 2013 |
Rembach A, Doecke JD, Roberts BR, Watt AD, Faux NG, Volitakis I, Pertile KK, Rumble RL, Trounson BO, Fowler CJ, Wilson W, Ellis KA, Martins RN, Rowe CC, Villemagne VL, ... ... Bush AI, et al. Longitudinal analysis of serum copper and ceruloplasmin in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 34: 171-82. PMID 23168449 DOI: 10.3233/Jad-121474 |
0.63 |
|
| 2013 |
Lim YY, Ellis KA, Harrington K, Pietrzak RH, Gale J, Ames D, Bush AI, Darby D, Martins RN, Masters CL, Rowe CC, Savage G, Szoeke C, Villemagne VL, Maruff P. Cognitive decline in adults with amnestic mild cognitive impairment and high amyloid-β: prodromal Alzheimer's disease? Journal of Alzheimer's Disease : Jad. 33: 1167-76. PMID 23160011 DOI: 10.3233/Jad-121771 |
0.51 |
|
| 2013 |
Ayton S, Lei P, Bush AI. Metallostasis in Alzheimer's disease. Free Radical Biology & Medicine. 62: 76-89. PMID 23142767 DOI: 10.1016/J.Freeradbiomed.2012.10.558 |
0.439 |
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| 2013 |
Lim YY, Pietrzak RH, Ellis KA, Jaeger J, Harrington K, Ashwood T, Szoeke C, Martins RN, Bush AI, Masters CL, Rowe CC, Villemagne VL, Ames D, Darby D, Maruff P. Rapid decline in episodic memory in healthy older adults with high amyloid-β. Journal of Alzheimer's Disease : Jad. 33: 675-9. PMID 23001710 DOI: 10.3233/Jad-2012-121516 |
0.495 |
|
| 2013 |
Greenough MA, Camakaris J, Bush AI. Metal dyshomeostasis and oxidative stress in Alzheimer's disease. Neurochemistry International. 62: 540-55. PMID 22982299 DOI: 10.1016/J.Neuint.2012.08.014 |
0.484 |
|
| 2013 |
Brown BM, Peiffer JJ, Taddei K, Lui JK, Laws SM, Gupta VB, Taddei T, Ward VK, Rodrigues MA, Burnham S, Rainey-Smith SR, Villemagne VL, Bush A, Ellis KA, Masters CL, et al. Physical activity and amyloid-β plasma and brain levels: results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing. Molecular Psychiatry. 18: 875-81. PMID 22889922 DOI: 10.1038/Mp.2012.107 |
0.581 |
|
| 2013 |
Bush AI. The metal theory of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 33: S277-81. PMID 22635102 DOI: 10.3233/Jad-2012-129011 |
0.473 |
|
| 2013 |
Duce JA, Ayton S, Miller AA, Tsatsanis A, Lam LQ, Leone L, Corbin JE, Butzkueven H, Kilpatrick TJ, Rogers JT, Barnham KJ, Finkelstein DI, Bush AI. Amine oxidase activity of β-amyloid precursor protein modulates systemic and local catecholamine levels. Molecular Psychiatry. 18: 245-54. PMID 22212595 DOI: 10.1038/Mp.2011.168 |
0.345 |
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| 2013 |
Lei P, Ayton S, Finkelstein D, Bush A. DT-03-05: Rescue of Behavioral and neurodegenerative phenotypes in symptomatic tau KO mice: Therapeutic implications for neurodegenerative diseases Alzheimer's & Dementia. 9: P848-P848. DOI: 10.1016/J.Jalz.2013.08.017 |
0.334 |
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| 2013 |
Restrepo C, Saling M, Ames D, Bush A, Faux N, Martins R, Maruff P, Masters C, Rowe C, Szoeke C, Villemagne V, Yates P, Ellis K. The effect of vascular risk factors on the rate of cognitive change in older adults: Data from the Australian Imaging Biomarkers and Lifestyle (AIBL) flagship study Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.05.911 |
0.493 |
|
| 2013 |
Lim YY, Villemagne V, Laws S, Ames D, Pietrzak R, Ellis K, Harrington K, Bourgeat P, Salvado O, Darby D, Snyder P, Bush A, Martins R, Masters C, Rowe C, et al. Modulation of beta-amyloid-related cognitive decline by brain-derived neurotrophic factor Val66Met polymorphism in preclinical Alzheimer's disease Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.05.893 |
0.613 |
|
| 2013 |
Lim YY, Ellis K, Harrington K, Kamer A, Pietrzak R, Bush A, Darby D, Martins R, Masters C, Rowe C, Savage G, Szoeke C, Villemagne V, Ames D, Maruff P. Cognitive consequences of high beta-amyloid levels in people with mild cognitive impairment and healthy older adults: Implications for early detection of Alzheimer's disease Alzheimers & Dementia. 9: 446. DOI: 10.1016/J.Jalz.2013.05.891 |
0.582 |
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| 2013 |
Zhang P, Graham P, Savage G, Jones A, Macaulay L, Masters C, Martins R, Gupta VB, Bush A, Maruff P, Ellis K, Szoeke C, Rowe C, Ames D, Wilson B. Change in cognition over 36 months in relation to blood biomarkers Alzheimers & Dementia. 9: 204. DOI: 10.1016/J.Jalz.2013.05.372 |
0.5 |
|
| 2013 |
Rembach A, Wilson B, Ellis K, Ames D, Rowe C, Villemagne V, Bush A, Martins R, Masters C, Doecke J. Neutrophil-lymphocyte ratio in Alzheimer's disease: Data from the Australian Imaging Biomarker and Lifestyle study of ageing Alzheimers & Dementia. 9: 203. DOI: 10.1016/J.Jalz.2013.05.368 |
0.577 |
|
| 2013 |
Maruff P, Lim YY, Ames D, Ellis K, Pietrzak R, Savage G, Harrington K, Bush A, Szoeke C, Martins R, Villemagne V, Rowe C, Darby D, Masters C. Clinical utility of the cogstate brief battery in Alzheimer's disease–related memory impairment Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.05.1296 |
0.54 |
|
| 2013 |
Rembach A, Wilson B, Villemagne V, Ellis K, Ames D, Rowe C, Bush A, Martins R, Masters C, Doecke J. Plasma beta-amyloid levels are significantly associated with a transition toward Alzheimer's disease as measured by cognitive decline and change in neocortical amyloid burden Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.04.341 |
0.627 |
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| 2013 |
Gupta VB, Rowe C, Szoeke C, Ames D, Cobiac L, Bush A, Ellis K, Macaulay L, Masters C, Martins R. Establishing apolipoprotein J as a potential candidate for Alzheimer's disease biomarker panel: Australian Imaging, Biomarker and Lifestyle (AIBL) flagship study of aging Alzheimers & Dementia. 9: 128. DOI: 10.1016/J.Jalz.2013.04.057 |
0.585 |
|
| 2012 |
Cherny RA, Ayton S, Finkelstein DI, Bush AI, McColl G, Massa SM. PBT2 Reduces Toxicity in a C. elegans Model of polyQ Aggregation and Extends Lifespan, Reduces Striatal Atrophy and Improves Motor Performance in the R6/2 Mouse Model of Huntington's Disease. Journal of Huntington's Disease. 1: 211-9. PMID 25063332 DOI: 10.3233/Jhd-120029 |
0.426 |
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| 2012 |
McColl G, Roberts BR, Pukala TL, Kenche VB, Roberts CM, Link CD, Ryan TM, Masters CL, Barnham KJ, Bush AI, Cherny RA. Utility of an improved model of amyloid-beta (Aβâ‚â‚‹â‚„â‚‚) toxicity in Caenorhabditis elegans for drug screening for Alzheimer's disease. Molecular Neurodegeneration. 7: 57. PMID 23171715 DOI: 10.1186/1750-1326-7-57 |
0.535 |
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| 2012 |
Doecke JD, Laws SM, Faux NG, Wilson W, Burnham SC, Lam CP, Mondal A, Bedo J, Bush AI, Brown B, De Ruyck K, Ellis KA, Fowler C, Gupta VB, Head R, et al. Blood-based protein biomarkers for diagnosis of Alzheimer disease. Archives of Neurology. 69: 1318-25. PMID 22801742 DOI: 10.1001/Archneurol.2012.1282 |
0.602 |
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| 2012 |
Manso Y, Carrasco J, Comes G, Adlard PA, Bush AI, Hidalgo J. Characterization of the role of the antioxidant proteins metallothioneins 1 and 2 in an animal model of Alzheimer's disease. Cellular and Molecular Life Sciences : Cmls. 69: 3665-81. PMID 22766972 DOI: 10.1007/S00018-012-1045-Y |
0.473 |
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| 2012 |
Manso Y, Carrasco J, Comes G, Meloni G, Adlard PA, Bush AI, Vašák M, Hidalgo J. Characterization of the role of metallothionein-3 in an animal model of Alzheimer's disease. Cellular and Molecular Life Sciences : Cmls. 69: 3683-700. PMID 22722772 DOI: 10.1007/S00018-012-1047-9 |
0.451 |
|
| 2012 |
Gunn AP, Roberts BR, Bush AI. Rapid generation of dityrosine cross-linked Aβ oligomers via Cu-redox cycling. Methods in Molecular Biology (Clifton, N.J.). 849: 3-10. PMID 22528079 DOI: 10.1007/978-1-61779-551-0_1 |
0.357 |
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| 2012 |
Hung LW, Villemagne VL, Cheng L, Sherratt NA, Ayton S, White AR, Crouch PJ, Lim S, Leong SL, Wilkins S, George J, Roberts BR, Pham CL, Liu X, Chiu FC, ... ... Bush AI, et al. The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease. The Journal of Experimental Medicine. 209: 837-54. PMID 22473957 DOI: 10.1084/Jem.20112285 |
0.439 |
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| 2012 |
Adlard PA, Bush AI. Metal chaperones: a holistic approach to the treatment of Alzheimer's disease. Frontiers in Psychiatry. 3: 15. PMID 22403554 DOI: 10.3389/Fpsyt.2012.00015 |
0.38 |
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| 2012 |
Rosas HD, Chen YI, Doros G, Salat DH, Chen NK, Kwong KK, Bush A, Fox J, Hersch SM. Alterations in brain transition metals in Huntington disease: an evolving and intricate story. Archives of Neurology. 69: 887-93. PMID 22393169 DOI: 10.1001/Archneurol.2011.2945 |
0.328 |
|
| 2012 |
Lei P, Ayton S, Finkelstein DI, Spoerri L, Ciccotosto GD, Wright DK, Wong BX, Adlard PA, Cherny RA, Lam LQ, Roberts BR, Volitakis I, Egan GF, McLean CA, Cappai R, ... ... Bush AI, et al. Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export. Nature Medicine. 18: 291-5. PMID 22286308 DOI: 10.1038/Nm.2613 |
0.453 |
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| 2012 |
Roberts BR, Ryan TM, Bush AI, Masters CL, Duce JA. The role of metallobiology and amyloid-β peptides in Alzheimer's disease. Journal of Neurochemistry. 120: 149-66. PMID 22121980 DOI: 10.1111/J.1471-4159.2011.07500.X |
0.575 |
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| 2012 |
James SA, Volitakis I, Adlard PA, Duce JA, Masters CL, Cherny RA, Bush AI. Elevated labile Cu is associated with oxidative pathology in Alzheimer disease. Free Radical Biology & Medicine. 52: 298-302. PMID 22080049 DOI: 10.1016/J.Freeradbiomed.2011.10.446 |
0.481 |
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| 2012 |
Sona A, Zhang P, Ames D, Bush AI, Lautenschlager NT, Martins RN, Masters CL, Rowe CC, Szoeke C, Taddei K, Ellis KA. Predictors of rapid cognitive decline in Alzheimer's disease: results from the Australian imaging, biomarkers and lifestyle (AIBL) study of ageing. International Psychogeriatrics / Ipa. 24: 197-204. PMID 21749739 DOI: 10.1017/S1041610211001335 |
0.578 |
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| 2012 |
Bush A. Metals in alzheimer’s disease Pathology. 44: S17. DOI: 10.1016/S0031-3025(16)32640-X |
0.454 |
|
| 2012 |
Appannah A, Szoeke C, Ellis K, Rowe C, Martins R, Masters C, Ames D, Bush A. Investigating cardiovascular risk factors on cognition: A two-cohort study Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.878 |
0.49 |
|
| 2012 |
Faux N, Burnham S, Wilson B, Jones G, Laws S, Bedo J, Ames D, Bush A, Doecke J, Ellis K, Head R, Kiiveri H, Macaulay L, Martins R, Masters C, et al. An update on an AIBL blood-based biomarker panel for the prediction of Aβ burden Alzheimers & Dementia. 8: 283. DOI: 10.1016/J.Jalz.2012.05.764 |
0.542 |
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| 2012 |
Gupta VB, Wilson A, Rainey-Smith S, Laws S, Bush A, Ellis K, Macaulay L, Rowe C, Szoeke C, Taddei K, Ames D, Masters C, Martins R. Establishing apolipoprotein E as a biomarker for Alzheimer's disease: Australian Imaging, Biomarker and Lifestyle (AIBL) Flagship Study of Ageing Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.285 |
0.58 |
|
| 2012 |
Laws S, Bender S, Rainey-Smith S, Wilson A, Gupta VB, Ruyck Kd, Bush A, Ellis K, Macaulay L, Rowe C, Szoeke C, Taddei K, Ames D, Masters C, Martins R. Alzheimer's disease–related changes in plasma cortisol levels and gene involvement in the AIBL study Alzheimers & Dementia. 8: 407. DOI: 10.1016/J.Jalz.2012.05.2034 |
0.561 |
|
| 2012 |
Laws S, Lam C, Mondal A, Bush A, Ellis K, Macaulay L, Rowe C, Taddei K, Szoeke C, Ames D, Masters C, Martins R. Gene combination associations with Alzheimer's disease risk and quantitative traits in the AIBL study Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.1838 |
0.571 |
|
| 2012 |
Restrepo C, Saling M, Yates P, Villemagne V, Ames D, Bush A, Faux N, Martins R, Masters C, Rowe C, Szoeke C, Ellis K. The effect of vascular risk factors on cognition in older adults: Data from the AIBL study Alzheimers & Dementia. 8: 635. DOI: 10.1016/J.Jalz.2012.05.1693 |
0.483 |
|
| 2011 |
Kaden D, Bush AI, Danzeisen R, Bayer TA, Multhaup G. Disturbed copper bioavailability in Alzheimer's disease. International Journal of Alzheimer's Disease. 2011: 345614. PMID 22145082 DOI: 10.4061/2011/345614 |
0.457 |
|
| 2011 |
Sensi SL, Paoletti P, Koh JY, Aizenman E, Bush AI, Hershfinkel M. The neurophysiology and pathology of brain zinc. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16076-85. PMID 22072659 DOI: 10.1523/Jneurosci.3454-11.2011 |
0.346 |
|
| 2011 |
Faux NG, Ellis KA, Porter L, Fowler CJ, Laws SM, Martins RN, Pertile KK, Rembach A, Rowe CC, Rumble RL, Szoeke C, Taddei K, Taddei T, Trounson BO, Villemagne VL, ... ... Bush AI, et al. Homocysteine, vitamin B12, and folic acid levels in Alzheimer's disease, mild cognitive impairment, and healthy elderly: baseline characteristics in subjects of the Australian Imaging Biomarker Lifestyle study. Journal of Alzheimer's Disease : Jad. 27: 909-22. PMID 21891867 DOI: 10.3233/Jad-2011-110752 |
0.584 |
|
| 2011 |
Manso Y, Comes G, Hidalgo J, Bush AI, Adlard PA. Copper modulation as a therapy for Alzheimer's disease? International Journal of Alzheimer's Disease. 2011: 370345. PMID 21876828 DOI: 10.4061/2011/370345 |
0.467 |
|
| 2011 |
Crouch PJ, Savva MS, Hung LW, Donnelly PS, Mot AI, Parker SJ, Greenough MA, Volitakis I, Adlard PA, Cherny RA, Masters CL, Bush AI, Barnham KJ, White AR. The Alzheimer's therapeutic PBT2 promotes amyloid-β degradation and GSK3 phosphorylation via a metal chaperone activity. Journal of Neurochemistry. 119: 220-30. PMID 21797865 DOI: 10.1111/J.1471-4159.2011.07402.X |
0.523 |
|
| 2011 |
Lei P, Ayton S, Bush AI, Adlard PA. GSK-3 in Neurodegenerative Diseases. International Journal of Alzheimer's Disease. 2011: 189246. PMID 21629738 DOI: 10.4061/2011/189246 |
0.404 |
|
| 2011 |
Fox JH, Connor T, Stiles M, Kama J, Lu Z, Dorsey K, Lieberman G, Liebermann G, Sapp E, Cherny RA, Banks M, Volitakis I, DiFiglia M, Berezovska O, Bush AI, et al. Cysteine oxidation within N-terminal mutant huntingtin promotes oligomerization and delays clearance of soluble protein. The Journal of Biological Chemistry. 286: 18320-30. PMID 21454633 DOI: 10.1074/Jbc.M110.199448 |
0.315 |
|
| 2011 |
Gupta VB, Laws SM, Villemagne VL, Ames D, Bush AI, Ellis KA, Lui JK, Masters C, Rowe CC, Szoeke C, Taddei K, Martins RN. Plasma apolipoprotein E and Alzheimer disease risk: the AIBL study of aging. Neurology. 76: 1091-8. PMID 21422459 DOI: 10.1212/Wnl.0B013E318211C352 |
0.604 |
|
| 2011 |
Adlard PA, Bica L, White AR, Nurjono M, Filiz G, Crouch PJ, Donnelly PS, Cappai R, Finkelstein DI, Bush AI. Metal ionophore treatment restores dendritic spine density and synaptic protein levels in a mouse model of Alzheimer's disease. Plos One. 6: e17669. PMID 21412423 DOI: 10.1371/Journal.Pone.0017669 |
0.358 |
|
| 2011 |
Sittironnarit G, Ames D, Bush AI, Faux N, Flicker L, Foster J, Hilmer S, Lautenschlager NT, Maruff P, Masters CL, Martins RN, Rowe C, Szoeke C, Ellis KA. Effects of anticholinergic drugs on cognitive function in older Australians: results from the AIBL study. Dementia and Geriatric Cognitive Disorders. 31: 173-8. PMID 21389718 DOI: 10.1159/000325171 |
0.554 |
|
| 2011 |
Greenough MA, Volitakis I, Li QX, Laughton K, Evin G, Ho M, Dalziel AH, Camakaris J, Bush AI. Presenilins promote the cellular uptake of copper and zinc and maintain copper chaperone of SOD1-dependent copper/zinc superoxide dismutase activity. The Journal of Biological Chemistry. 286: 9776-86. PMID 21239495 DOI: 10.1074/Jbc.M110.163964 |
0.427 |
|
| 2011 |
Acevedo KM, Hung YH, Dalziel AH, Li QX, Laughton K, Wikhe K, Rembach A, Roberts B, Masters CL, Bush AI, Camakaris J. Copper promotes the trafficking of the amyloid precursor protein. The Journal of Biological Chemistry. 286: 8252-62. PMID 21177866 DOI: 10.1074/Jbc.M110.128512 |
0.534 |
|
| 2011 |
Adlard PA, Bush AI. The plasma membrane redox system in Alzheimer's disease. Experimental Neurology. 228: 9-14. PMID 21168407 DOI: 10.1016/J.Expneurol.2010.12.009 |
0.355 |
|
| 2011 |
Duce JA, Bush AI, Adlard PA. Role of amyloid-β-metal interactions in Alzheimers disease Future Neurology. 6: 641-659. DOI: 10.2217/Fnl.11.43 |
0.421 |
|
| 2011 |
Burnham S, Faux N, Laws SM, Wilson W, Salvado O, Ames D, Bush A, Doecke J, Ellis K, Kiiveri H, Martins RN, Masters C. A blood-based predictor for neocortical amyloid load in Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.09.033 |
0.527 |
|
| 2011 |
Rembach A, Rowe C, Ellis K, Doecke J, Masters C, Martins R, Faux N, Duce J, Ames D, Volitakis I, Bush A, Roberts B, Trounson B, Fowler C, Pertile K, et al. Plasma copper and ceruloplasmin are not altered in Alzheimer's disease: Baseline data in the Australian Imaging Biomarker Lifestyle (AIBL) study of Ageing Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.386 |
0.593 |
|
| 2011 |
Doecke J, Ames D, Laws S, Burnham S, Macaulay L, Bush A, Wilson B, Ellis K, Masters C, Martins RNW, Faux N. Change in blood pathology biomarkers to predict Alzheimer's disease: An AIBL 18-month update Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.359 |
0.497 |
|
| 2011 |
Bush A. APP, tau and presenilin: The metal ion regulatory proteins of Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.2318 |
0.423 |
|
| 2011 |
Gunn A, Duce J, McLean C, Bush A, Cherny R. Glutaminyl cyclase activity is decreased in Alzheimer's cerebrospinal fluid Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1621 |
0.348 |
|
| 2011 |
Duce J, Lei P, Tsatsanis A, Ayton S, Lam L, Adlard P, Ciccotosto G, Masters C, Cappai R, Barnham K, Rogers J, Finkelstein D, Bush A. The relationship between beta-amyloid protein precursor and tau in Alzheimer's disease-related iron disruption Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1422 |
0.554 |
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| 2011 |
Cherny R, Adlard P, Barnham K, Bush A, Finkelstein D, Massa S, White A, Crouch P. P2-451: The Alzheimer's therapeutic PBT2 achieves cognitive benefit by combining neuroprotection with neurorestoration: studies in animal models of Alzheimer's disease and Huntington's disease Alzheimer's & Dementia. 7: S457-S457. DOI: 10.1016/J.Jalz.2011.05.1323 |
0.421 |
|
| 2010 |
Norgate M, Southon A, Greenough M, Cater M, Farlow A, Batterham P, Bush AI, Subramaniam VN, Burke R, Camakaris J. Syntaxin 5 is required for copper homeostasis in Drosophila and mammals. Plos One. 5: e14303. PMID 21188142 DOI: 10.1371/Journal.Pone.0014303 |
0.302 |
|
| 2010 |
Duce JA, Tsatsanis A, Cater MA, James SA, Robb E, Wikhe K, Leong SL, Perez K, Johanssen T, Greenough MA, Cho HH, Galatis D, Moir RD, Masters CL, McLean C, ... ... Bush AI, et al. Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease. Cell. 142: 857-67. PMID 20817278 DOI: 10.1016/J.Cell.2010.08.014 |
0.635 |
|
| 2010 |
Lei P, Ayton S, Finkelstein DI, Adlard PA, Masters CL, Bush AI. Tau protein: relevance to Parkinson's disease. The International Journal of Biochemistry & Cell Biology. 42: 1775-8. PMID 20678581 DOI: 10.1016/J.Biocel.2010.07.016 |
0.511 |
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| 2010 |
Zheng Z, White C, Lee J, Peterson TS, Bush AI, Sun GY, Weisman GA, Petris MJ. Altered microglial copper homeostasis in a mouse model of Alzheimer's disease. Journal of Neurochemistry. 114: 1630-8. PMID 20626553 DOI: 10.1111/J.1471-4159.2010.06888.X |
0.456 |
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| 2010 |
Lee JY, Cho E, Kim TY, Kim DK, Palmiter RD, Volitakis I, Kim JS, Bush AI, Koh JY. Apolipoprotein E ablation decreases synaptic vesicular zinc in the brain. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 23: 1085-95. PMID 20556483 DOI: 10.1007/S10534-010-9354-9 |
0.454 |
|
| 2010 |
Duce JA, Bush AI. Biological metals and Alzheimer's disease: implications for therapeutics and diagnostics. Progress in Neurobiology. 92: 1-18. PMID 20444428 DOI: 10.1016/J.Pneurobio.2010.04.003 |
0.367 |
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| 2010 |
Lui JK, Laws SM, Li QX, Villemagne VL, Ames D, Brown B, Bush AI, De Ruyck K, Dromey J, Ellis KA, Faux NG, Foster J, Fowler C, Gupta V, Hudson P, et al. Plasma amyloid-beta as a biomarker in Alzheimer's disease: the AIBL study of aging. Journal of Alzheimer's Disease : Jad. 20: 1233-42. PMID 20413897 DOI: 10.3233/Jad-2010-090249 |
0.633 |
|
| 2010 |
Perreau VM, Orchard S, Adlard PA, Bellingham SA, Cappai R, Ciccotosto GD, Cowie TF, Crouch PJ, Duce JA, Evin G, Faux NG, Hill AF, Hung YH, James SA, Li QX, ... ... Bush AI, et al. A domain level interaction network of amyloid precursor protein and Abeta of Alzheimer's disease. Proteomics. 10: 2377-95. PMID 20391539 DOI: 10.1002/Pmic.200900773 |
0.515 |
|
| 2010 |
Faux NG, Ritchie CW, Gunn A, Rembach A, Tsatsanis A, Bedo J, Harrison J, Lannfelt L, Blennow K, Zetterberg H, Ingelsson M, Masters CL, Tanzi RE, Cummings JL, Herd CM, ... Bush AI, et al. PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses. Journal of Alzheimer's Disease : Jad. 20: 509-16. PMID 20164561 DOI: 10.3233/Jad-2010-1390 |
0.611 |
|
| 2010 |
Adlard PA, Parncutt JM, Finkelstein DI, Bush AI. Cognitive loss in zinc transporter-3 knock-out mice: a phenocopy for the synaptic and memory deficits of Alzheimer's disease? The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1631-6. PMID 20130173 DOI: 10.1523/Jneurosci.5255-09.2010 |
0.369 |
|
| 2010 |
Boon WC, van den Buuse M, Wegener N, Martin S, Chua HK, Bush AI, Masters CL, Adlard PA, Li QX. Behavioural phenotype of APPC100.V717F transgenic mice over-expressing a mutant Abeta-bearing fragment is associated with reduced NMDA receptor density. Behavioural Brain Research. 209: 27-35. PMID 20085783 DOI: 10.1016/J.Bbr.2010.01.013 |
0.422 |
|
| 2010 |
Haeffner F, Barnham KJ, Bush AI, Brinck T. Generation of soluble oligomeric beta-amyloid species via copper catalyzed oxidation with implications for Alzheimer's disease: a DFT study. Journal of Molecular Modeling. 16: 1103-8. PMID 19924451 DOI: 10.1007/S00894-009-0619-6 |
0.401 |
|
| 2010 |
Baum L, Chan IH, Cheung SK, Goggins WB, Mok V, Lam L, Leung V, Hui E, Ng C, Woo J, Chiu HF, Zee BC, Cheng W, Chan MH, Szeto S, ... ... Bush AI, et al. Serum zinc is decreased in Alzheimer's disease and serum arsenic correlates positively with cognitive ability. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 23: 173-9. PMID 19911117 DOI: 10.1007/S10534-009-9277-5 |
0.478 |
|
| 2010 |
Hung YH, Bush AI, Cherny RA. Copper in the brain and Alzheimer's disease. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 15: 61-76. PMID 19862561 DOI: 10.1007/S00775-009-0600-Y |
0.499 |
|
| 2010 |
Cherny RA, Adlard P, Barnham K, Bush A, Finkelstein DI, White A, Massa SM. O4-08-03: Novel Molecular Mechanisms for the Neurotrophic and Neuroprotective Effects of Pbt2 in Alzheimer's Disease and Huntington's Disease Alzheimer's & Dementia. 6: e18-e19. DOI: 10.1016/J.Jalz.2010.08.056 |
0.374 |
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| 2010 |
Doecke J, Buckley M, Good N, Laws S, Faux N, Dunne R, Wilson W, Bush A, Ames D, Ellis K, Rowe C, Szoeke C, Martins R, Masters C. Identifying protein biomarkers for early diagnosis of Alzheimer's disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.407 |
0.592 |
|
| 2010 |
Faux NG, Ellis KA, Ames D, Fowler CJ, Martins RM, Pertile KK, Rowe C, Rumble RL, Szoeke C, Rembach A, Trounson B, Masters C, Bush AI. Alzheimer's disease is associated with lower hemoglobin levels and anemia: The Australian Imaging Biomarker Lifestyle (AIBL) study of aging Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1761 |
0.504 |
|
| 2010 |
Faux NG, Ellis KA, Fowler CJ, Martins R, Pertile KK, Rowe C, Rumble RL, Szoeke C, Porter L, Rembach A, Trounson B, Masters C, Ames D, Bush AI. Plasma levels of homocysteine and red cell folate correlate with neurological composite z-scores in Alzheimer's disease and healthy subjects: The Australian Imaging Biomarker Lifestyle (AIBL) study of aging Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1726 |
0.569 |
|
| 2010 |
Laws SM, Verdile G, Ames D, Bush AI, Ellis KA, Gupta V, Lui JK, Masters CL, Rowe CC, Szoeke C, Taddei K, Villemagne VL, Martins RN. Associations between gonadotropins, testosterone, plasma Aβ and PiB retention in men with subjective memory complaints or mild cognitive impairment Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1708 |
0.641 |
|
| 2010 |
Laws SM, Mondal A, Lam C, Ames D, Bush AI, Ellis KA, Doecke J, Faux NG, Gupta V, Lui JK, Masters CL, Rowe CC, Szoeke C, Taddei K, Villemagne VL, et al. Analysis of Peripheral Blood Biomarkers: Towards the Early Diagnosis Alzheimer's Disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.153 |
0.486 |
|
| 2010 |
Ellis KA, Bush AI, Foster J, Martins RN, Maruff P, Masters CL, Rowe CC, Savage G, Szoeke C, Ames D. P2-178: Findings from the first 18-month follow up of the Australian Imaging Biomarkers and Lifestyle (AIBL) cohort Alzheimer's & Dementia. 6: S365-S366. DOI: 10.1016/J.Jalz.2010.05.1226 |
0.489 |
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| 2009 |
Sensi SL, Paoletti P, Bush AI, Sekler I. Zinc in the physiology and pathology of the CNS. Nature Reviews. Neuroscience. 10: 780-91. PMID 19826435 DOI: 10.1038/Nrn2734 |
0.331 |
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| 2009 |
George JL, Mok S, Moses D, Wilkins S, Bush AI, Cherny RA, Finkelstein DI. Targeting the progression of Parkinson's disease. Current Neuropharmacology. 7: 9-36. PMID 19721815 DOI: 10.2174/157015909787602814 |
0.323 |
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| 2009 |
McColl G, Roberts BR, Gunn AP, Perez KA, Tew DJ, Masters CL, Barnham KJ, Cherny RA, Bush AI. The Caenorhabditis elegans A beta 1-42 model of Alzheimer disease predominantly expresses A beta 3-42. The Journal of Biological Chemistry. 284: 22697-702. PMID 19574211 DOI: 10.1074/Jbc.C109.028514 |
0.459 |
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| 2009 |
Hung YH, Robb EL, Volitakis I, Ho M, Evin G, Li QX, Culvenor JG, Masters CL, Cherny RA, Bush AI. Paradoxical condensation of copper with elevated beta-amyloid in lipid rafts under cellular copper deficiency conditions: implications for Alzheimer disease. The Journal of Biological Chemistry. 284: 21899-907. PMID 19542222 DOI: 10.1074/Jbc.M109.019521 |
0.547 |
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| 2009 |
Adlard PA, James SA, Bush AI, Masters CL. beta-Amyloid as a molecular therapeutic target in Alzheimer's disease. Drugs of Today (Barcelona, Spain : 1998). 45: 293-304. PMID 19499094 DOI: 10.1358/Dot.2009.45.4.1353853 |
0.549 |
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| 2009 |
Ellis KA, Bush AI, Darby D, De Fazio D, Foster J, Hudson P, Lautenschlager NT, Lenzo N, Martins RN, Maruff P, Masters C, Milner A, Pike K, Rowe C, Savage G, et al. The Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging: methodology and baseline characteristics of 1112 individuals recruited for a longitudinal study of Alzheimer's disease. International Psychogeriatrics / Ipa. 21: 672-87. PMID 19470201 DOI: 10.1017/S1041610209009405 |
0.591 |
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| 2009 |
Maynard CJ, Cappai R, Volitakis I, Laughton KM, Masters CL, Bush AI, Li QX. Chronic exposure to high levels of zinc or copper has little effect on brain metal homeostasis or Abeta accumulation in transgenic APP-C100 mice. Cellular and Molecular Neurobiology. 29: 757-67. PMID 19381799 DOI: 10.1007/S10571-009-9401-7 |
0.537 |
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| 2009 |
Minniti AN, Rebolledo DL, Grez PM, Fadic R, Aldunate R, Volitakis I, Cherny RA, Opazo C, Masters C, Bush AI, Inestrosa NC. Intracellular amyloid formation in muscle cells of Abeta-transgenic Caenorhabditis elegans: determinants and physiological role in copper detoxification. Molecular Neurodegeneration. 4: 2. PMID 19126228 DOI: 10.1186/1750-1326-4-2 |
0.523 |
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| 2009 |
Crouch PJ, Hung LW, Adlard PA, Cortes M, Lal V, Filiz G, Perez KA, Nurjono M, Caragounis A, Du T, Laughton K, Volitakis I, Bush AI, Li QX, Masters CL, et al. Increasing Cu bioavailability inhibits Abeta oligomers and tau phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 106: 381-6. PMID 19122148 DOI: 10.1073/Pnas.0809057106 |
0.567 |
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| 2009 |
Biran Y, Masters CL, Barnham KJ, Bush AI, Adlard PA. Pharmacotherapeutic targets in Alzheimer's disease. Journal of Cellular and Molecular Medicine. 13: 61-86. PMID 19040415 DOI: 10.1111/J.1582-4934.2008.00595.X |
0.576 |
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| 2009 |
Strozyk D, Launer LJ, Adlard PA, Cherny RA, Tsatsanis A, Volitakis I, Blennow K, Petrovitch H, White LR, Bush AI. Zinc and copper modulate Alzheimer Abeta levels in human cerebrospinal fluid. Neurobiology of Aging. 30: 1069-77. PMID 18068270 DOI: 10.1016/J.Neurobiolaging.2007.10.012 |
0.469 |
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| 2009 |
Hung L, Roberts B, Wilkins S, George J, Pham C, Lim S, Crouch P, Nurjono M, Gunawan L, Critch N, Sherratt N, Cherny R, Bush A, Masters C, Culvenor J, et al. P2.097 A reactive nitrogen species scavenger is neuroprotective in multiple Parkinson's disease animal models Parkinsonism & Related Disorders. 15: S115. DOI: 10.1016/S1353-8020(09)70448-1 |
0.473 |
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| 2009 |
George J, Wilkins S, Critch N, Gunawan L, Cortes M, Liu X, Laughton K, Nurjono M, Volitakis I, Huggins P, Parsons J, McNaughton M, Adlard P, Masters C, Cappai R, ... ... Bush A, et al. P1.050 Novel neuroprotective agents for the treatment of Parkinson's disease Parkinsonism & Related Disorders. 15: S41-S42. DOI: 10.1016/S1353-8020(09)70172-5 |
0.435 |
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| 2009 |
Milner A, Ellis K, Bush A, Masters C, De Fazio D, Foster J, Hudson P, Lautenschlager N, Lenzo N, Martins R, Pike K, Rowe C, Savage G, Szoeke C, Taddei K, et al. IN54-TH-01 Biomarkers for Alzheimer's disease from large cohort studies Journal of the Neurological Sciences. 285: S40. DOI: 10.1016/S0022-510X(09)70189-3 |
0.506 |
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| 2009 |
Bush AI, Cherny RA, Finkelstein D, Masters CL, Tanzi RE, Barnham KJ, Ritchie C, Adlard PA. S4-04-05: Pbt2 for Pre-dementia Alzheimer's Disease: Animal and Clinical Evidence Alzheimer's & Dementia. 5: e5-e5. DOI: 10.1016/J.Jalz.2009.07.132 |
0.61 |
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| 2009 |
Ritchie CW, Bush A. F1-01-03: PBT2 for Alzheimer's disease: An update on clinical development Alzheimer's & Dementia. 5: P74-P74. DOI: 10.1016/J.Jalz.2009.05.176 |
0.35 |
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| 2009 |
Szoeke C, Ellis KA, Bush A, Darby D, Fazio DD, Foster J, Hudson P, Lautenschlager N, Lenzo N, Martins R, Maruff P, Masters C, Milner A, Pike K, Rowe C, et al. The AIBL study: Baseline data from a multicenter, prospective longitudinal study of ageing in 1,100 volunteers Alzheimers & Dementia. 5: 10. DOI: 10.1016/J.Jalz.2009.05.033 |
0.478 |
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| 2008 |
Rogers JT, Bush AI, Cho HH, Smith DH, Thomson AM, Friedlich AL, Lahiri DK, Leedman PJ, Huang X, Cahill CM. Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's disease. Biochemical Society Transactions. 36: 1282-7. PMID 19021541 DOI: 10.1042/Bst0361282 |
0.415 |
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| 2008 |
Bush AI. Drug development based on the metals hypothesis of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 15: 223-40. PMID 18953111 DOI: 10.3233/Jad-2008-15208 |
0.435 |
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| 2008 |
Wu WH, Lei P, Liu Q, Hu J, Gunn AP, Chen MS, Rui YF, Su XY, Xie ZP, Zhao YF, Bush AI, Li YM. Sequestration of copper from beta-amyloid promotes selective lysis by cyclen-hybrid cleavage agents. The Journal of Biological Chemistry. 283: 31657-64. PMID 18728006 DOI: 10.1074/Jbc.M804722200 |
0.44 |
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| 2008 |
Lannfelt L, Blennow K, Zetterberg H, Batsman S, Ames D, Harrison J, Masters CL, Targum S, Bush AI, Murdoch R, Wilson J, Ritchie CW. Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial. The Lancet. Neurology. 7: 779-86. PMID 18672400 DOI: 10.1016/S1474-4422(08)70167-4 |
0.516 |
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| 2008 |
Bush AI, Tanzi RE. Therapeutics for Alzheimer's disease based on the metal hypothesis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 5: 421-32. PMID 18625454 DOI: 10.1016/J.Nurt.2008.05.001 |
0.612 |
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| 2008 |
Adlard PA, Cherny RA, Finkelstein DI, Gautier E, Robb E, Cortes M, Volitakis I, Liu X, Smith JP, Perez K, Laughton K, Li QX, Charman SA, Nicolazzo JA, Wilkins S, ... ... Bush AI, et al. Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta. Neuron. 59: 43-55. PMID 18614028 DOI: 10.1016/J.Neuron.2008.06.018 |
0.673 |
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| 2008 |
Barnham KJ, Kenche VB, Ciccotosto GD, Smith DP, Tew DJ, Liu X, Perez K, Cranston GA, Johanssen TJ, Volitakis I, Bush AI, Masters CL, White AR, Smith JP, Cherny RA, et al. Platinum-based inhibitors of amyloid-beta as therapeutic agents for Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 105: 6813-8. PMID 18463291 DOI: 10.1073/Pnas.0800712105 |
0.53 |
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| 2008 |
Du T, La Fontaine SL, Abdo M, Bellingham SA, Greenough M, Volitakis I, Cherny RA, Bush AI, Hudson PJ, Camakaris J, Mercer JF, Crouch PJ, Masters CL, Perreau VM, White AR. Investigating copper-regulated protein expression in Menkes fibroblasts using antibody microarrays. Proteomics. 8: 1819-31. PMID 18384105 DOI: 10.1002/Pmic.200700895 |
0.421 |
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| 2008 |
Barnham KJ, Bush AI. Metals in Alzheimer's and Parkinson's diseases. Current Opinion in Chemical Biology. 12: 222-8. PMID 18342639 DOI: 10.1016/J.Cbpa.2008.02.019 |
0.413 |
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| 2008 |
Cater MA, McInnes KT, Li QX, Volitakis I, La Fontaine S, Mercer JF, Bush AI. Intracellular copper deficiency increases amyloid-beta secretion by diverse mechanisms. The Biochemical Journal. 412: 141-52. PMID 18248325 DOI: 10.1042/Bj20080103 |
0.433 |
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| 2008 |
Bush AI, Curtain CC. Twenty years of metallo-neurobiology: where to now? European Biophysics Journal : Ebj. 37: 241-5. PMID 17994233 DOI: 10.1007/S00249-007-0228-1 |
0.386 |
|
| 2008 |
Crouch PJ, Harding SM, White AR, Camakaris J, Bush AI, Masters CL. Mechanisms of A beta mediated neurodegeneration in Alzheimer's disease. The International Journal of Biochemistry & Cell Biology. 40: 181-98. PMID 17804276 DOI: 10.1016/J.Biocel.2007.07.013 |
0.532 |
|
| 2008 |
Cherny RA, Adlard PA, Finkelstein DI, Gautier E, Huggins P, Parsons J, Ritchie CW, Robb E, Cortes M, Volitakis I, Liu X, Smith JP, Perez K, Laughton K, Li Q, ... ... Bush AI, et al. O3-05-04: The 8-hydroxyquinoline analog PBT2 rapidly restores cognition and reduces soluble Abeta in Alzheimer transgenic mice Alzheimer's & Dementia. 4: T169-T169. DOI: 10.1016/J.Jalz.2008.05.444 |
0.412 |
|
| 2008 |
Duce JA, Rogers JT, Tsatsanis A, Moir RD, Robb E, Leong SL, Harding SM, Venti A, Masters C, Cappai R, Tanzi RE, Bush AI. P3-325: Alzheimer's disease β-amyloid protein precursor is ferroxidase II, a ceruloplasmin-like iron detoxification enzyme Alzheimer's & Dementia. 4: T617-T617. DOI: 10.1016/J.Jalz.2008.05.1894 |
0.617 |
|
| 2008 |
Biran Y, Bellingham SA, Lim CM, Volitakis I, Laughton KM, Li Q, Opazo C, Lui XM, Cherny RA, Bush AI. P2-416: Clioquinol mediates the cellular uptake of Alzheimer's disease amyloid-β peptide and copper Alzheimer's & Dementia. 4: T495-T495. DOI: 10.1016/J.Jalz.2008.05.1495 |
0.426 |
|
| 2008 |
Barnham KJ, Kenche VB, Ciccotosto GD, Smith DP, Tew DJ, Liu X, Perez K, Cranston G, Johanssen T, Volitakis I, Bush AI, Masters CL, White AR, Smith JP, Cherny RA, et al. P2-293: Platinum-based inhibitors of amyloid-β as therapeutic agents for Alzheimer's disease Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1369 |
0.509 |
|
| 2008 |
Barnham KJ, Crouch PJ, Filiz G, Cherny RA, Laughton K, Volitakis I, Bush AI, Masters CL, Cappai R, White AR. P2-292: Second generation MPAC PBT2 inhibits tau phosphorylation and promotes Aβ degradation Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1368 |
0.451 |
|
| 2007 |
Stoltenberg M, Bush AI, Bach G, Smidt K, Larsen A, Rungby J, Lund S, Doering P, Danscher G. Amyloid plaques arise from zinc-enriched cortical layers in APP/PS1 transgenic mice and are paradoxically enlarged with dietary zinc deficiency. Neuroscience. 150: 357-69. PMID 17949919 DOI: 10.1016/J.Neuroscience.2007.09.025 |
0.436 |
|
| 2007 |
Crouch PJ, Cimdins K, Duce JA, Bush AI, Trounce IA. Mitochondria in aging and Alzheimer's disease. Rejuvenation Research. 10: 349-57. PMID 17708691 DOI: 10.1089/Rej.2007.0592 |
0.451 |
|
| 2007 |
Crouch PJ, White AR, Bush AI. The modulation of metal bio-availability as a therapeutic strategy for the treatment of Alzheimer's disease. The Febs Journal. 274: 3775-83. PMID 17617225 DOI: 10.1111/J.1742-4658.2007.05918.X |
0.481 |
|
| 2007 |
Melov S, Adlard PA, Morten K, Johnson F, Golden TR, Hinerfeld D, Schilling B, Mavros C, Masters CL, Volitakis I, Li QX, Laughton K, Hubbard A, Cherny RA, Gibson B, ... Bush AI, et al. Mitochondrial oxidative stress causes hyperphosphorylation of tau. Plos One. 2: e536. PMID 17579710 DOI: 10.1371/Journal.Pone.0000536 |
0.491 |
|
| 2007 |
Fox JH, Kama JA, Lieberman G, Chopra R, Dorsey K, Chopra V, Volitakis I, Cherny RA, Bush AI, Hersch S. Mechanisms of copper ion mediated Huntington's disease progression. Plos One. 2: e334. PMID 17396163 DOI: 10.1371/Journal.Pone.0000334 |
0.388 |
|
| 2006 |
Crouch PJ, Barnham KJ, Bush AI, White AR. Therapeutic treatments for Alzheimer's disease based on metal bioavailability. Drug News & Perspectives. 19: 469-74. PMID 17160147 DOI: 10.1358/Dnp.2006.19.8.1021492 |
0.478 |
|
| 2006 |
Adlard PA, Bush AI. Metals and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 10: 145-63. PMID 17119284 DOI: 10.3233/Jad-2006-102-303 |
0.463 |
|
| 2006 |
Tucker S, Ahl M, Cho HH, Bandyopadhyay S, Cuny GD, Bush AI, Goldstein LE, Westaway D, Huang X, Rogers JT. RNA therapeutics directed to the non coding regions of APP mRNA, in vivo anti-amyloid efficacy of paroxetine, erythromycin, and N-acetyl cysteine. Current Alzheimer Research. 3: 221-7. PMID 16842099 DOI: 10.2174/156720506777632835 |
0.412 |
|
| 2006 |
Religa D, Strozyk D, Cherny RA, Volitakis I, Haroutunian V, Winblad B, Naslund J, Bush AI. Elevated cortical zinc in Alzheimer disease. Neurology. 67: 69-75. PMID 16832080 DOI: 10.1212/01.Wnl.0000223644.08653.B5 |
0.489 |
|
| 2006 |
White AR, Barnham KJ, Bush AI. Metal homeostasis in Alzheimer's disease. Expert Review of Neurotherapeutics. 6: 711-22. PMID 16734519 DOI: 10.1586/14737175.6.5.711 |
0.45 |
|
| 2006 |
White AR, Du T, Laughton KM, Volitakis I, Sharples RA, Xilinas ME, Hoke DE, Holsinger RM, Evin G, Cherny RA, Hill AF, Barnham KJ, Li QX, Bush AI, Masters CL. Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity. The Journal of Biological Chemistry. 281: 17670-80. PMID 16648635 DOI: 10.1074/Jbc.M602487200 |
0.55 |
|
| 2006 |
Smith DP, Smith DG, Curtain CC, Boas JF, Pilbrow JR, Ciccotosto GD, Lau TL, Tew DJ, Perez K, Wade JD, Bush AI, Drew SC, Separovic F, Masters CL, Cappai R, et al. Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge. The Journal of Biological Chemistry. 281: 15145-54. PMID 16595673 DOI: 10.1074/Jbc.M600417200 |
0.513 |
|
| 2006 |
Maynard CJ, Cappai R, Volitakis I, Cherny RA, Masters CL, Li QX, Bush AI. Gender and genetic background effects on brain metal levels in APP transgenic and normal mice: implications for Alzheimer beta-amyloid pathology. Journal of Inorganic Biochemistry. 100: 952-62. PMID 16574231 DOI: 10.1016/J.Jinorgbio.2006.02.010 |
0.557 |
|
| 2006 |
Opazo C, Luza S, Villemagne VL, Volitakis I, Rowe C, Barnham KJ, Strozyk D, Masters CL, Cherny RA, Bush AI. Radioiodinated clioquinol as a biomarker for beta-amyloid: Zn complexes in Alzheimer's disease. Aging Cell. 5: 69-79. PMID 16441845 DOI: 10.1111/J.1474-9726.2006.00196.X |
0.585 |
|
| 2006 |
Ayton S, Wang Y, Diouf I, Schneider JA, Brockman J, Morris MC, Bush AI. P2-473: BRAIN IRON IS A CO-PATHOLOGY THAT IS STRONGLY ASSOCIATED WITH COGNITIVE DECLINE IN PEOPLE WITH ALZHEIMER'S PATHOLOGY Alzheimer's & Dementia. 14: P904-P904. DOI: 10.1016/J.Jalz.2018.06.1166 |
0.399 |
|
| 2006 |
Greenough MA, Volitakis I, Li Q, Cherny RA, Camakaris J, Bush AI. P2-036: Inhibition of Alzheimer's disease amyloid-β production causes copper deficiency and decreased Cu/Zn SOD activity Alzheimer's & Dementia. 2: S242-S242. DOI: 10.1016/J.Jalz.2006.05.873 |
0.409 |
|
| 2006 |
Cater MA, Tsatsanis A, Volitakis I, Li Q, Evin G, Mercer JF, Masters CL, Cherny RA, Bush AI. P2-025: Copper depletion by menkes ATP7A over-expression dramatically alters the metabolism of APP and APLP2 in cell culture Alzheimer's & Dementia. 2: S239-S239. DOI: 10.1016/J.Jalz.2006.05.862 |
0.405 |
|
| 2006 |
Monty J, Adlard PA, Volitakis I, Cortes M, Li Q, Laughton K, McLean C, Masters CL, Cherny R, Villemagne VL, Bush AI. P1-384: Association of AD neuropathological hallmarks with biological metals Alzheimer's & Dementia. 2: S210-S210. DOI: 10.1016/J.Jalz.2006.05.762 |
0.487 |
|
| 2006 |
James SA, Monty J, Adlard PA, Villemagne V, Wedd AG, Bush AI. O4-02-05: Total exchangeable Cu2+
protein binding sites are elevated in Alzheimer's disease Alzheimer's & Dementia. 2: S78-S78. DOI: 10.1016/J.Jalz.2006.05.304 |
0.363 |
|
| 2006 |
Cherny RA, Barnham KJ, Bush AI, Cappai R, Gautier EC, Masters CL, Carrington D, Kocak G, Volitakis I, Kok GB. P4-435: PBT2, a novel MPAC for the treatment of Alzheimer's disease Alzheimer's & Dementia. 2: S646-S646. DOI: 10.1016/J.Jalz.2006.05.2177 |
0.502 |
|
| 2006 |
Liu XM, Mavros C, Bush AI, Masters CL, Saido TC, Kato Y, Cherny RA. P4-283: Clioquinol inhibits the metal-mediated generation of dityrosine and pyroglutamate variants of Abeta Alzheimer's & Dementia. 2: S600-S600. DOI: 10.1016/J.Jalz.2006.05.2022 |
0.447 |
|
| 2006 |
Bellingham SA, Opazo C, Camakaris J, Masters CL, Cherny R, Bush AI. P4-274: Copper-dependent uptake of clioquinol in neuronal cells is promoted by β-amyloid Alzheimer's & Dementia. 2: S597-S597. DOI: 10.1016/J.Jalz.2006.05.2013 |
0.435 |
|
| 2006 |
Mavros C, Bush AI, Ciccotosto GG, Masters CL, Cherny RA. P4-033: Oxidatively modified soluble Aβ oligomers accumulate progressively in APP-overexpressing mice Alzheimer's & Dementia. 2: S523-S523. DOI: 10.1016/J.Jalz.2006.05.1771 |
0.475 |
|
| 2006 |
Religa D, Strozyk D, Cherny R, Volitakis I, Haroutunian V, Naslund J, Winblad B, Bush AI. P4-019: Positive correlation of brain zinc with Alzheimer's disease β-amyloid burden Alzheimer's & Dementia. 2: S519-S519. DOI: 10.1016/J.Jalz.2006.05.1757 |
0.425 |
|
| 2006 |
Wilkins S, Deleva K, Cortes M, Mok SS, Culvenor JG, Vais A, Finkelstein DI, Masters CL, Cappai R, Barnham KJ, Bush AI, Cherny RA. P3-446: Significant reduction in 6-hydroxy-dopamine nigral lesion size by administration of clioquinol Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1717 |
0.34 |
|
| 2006 |
Adlard PA, Melov S, Morten K, Johnson F, Golden T, Hinerfeld D, Schilling B, Tsatsanis A, Li Q, Laughton K, Doctrow SR, Masters CL, Volitakis I, Cherny RA, Gibson B, ... Bush AI, et al. P3-362: Mitochondrial oxidative stress modulates amyloid pathology and the hyperphosphorylation of tau Alzheimer's & Dementia. 2: S481-S482. DOI: 10.1016/J.Jalz.2006.05.1632 |
0.446 |
|
| 2006 |
Barnham KJ, Smith D, Smith DG, Curtain CC, Boas JF, Pilbrow JR, Ciccotosto GD, Lau T, Tew DJ, Perez K, Drew SC, Separovic F, Wade JD, Cherny RA, Bush AI, et al. P3-357: Abeta redox chemistry and neurotoxicity Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1627 |
0.456 |
|
| 2006 |
Robb EL, Hung YH, Volitakis I, Cherny R, Bush AI. P3-313: Copper induces accumulation of tau and phosphorylated tau in lipid rafts Alzheimer's & Dementia. 2: S467-S467. DOI: 10.1016/J.Jalz.2006.05.1583 |
0.325 |
|
| 2006 |
Harding SE, Camakaris J, Cappai R, Hill AF, Bush AI. P3-249: The Aβ and ectodomain copper binding sites on the amyloid precursor protein markedly affect processing Alzheimer's & Dementia. 2: S448-S448. DOI: 10.1016/J.Jalz.2006.05.1518 |
0.379 |
|
| 2005 |
Haeffner F, Smith DG, Barnham KJ, Bush AI. Model studies of cholesterol and ascorbate oxidation by copper complexes: relevance to Alzheimer's disease beta-amyloid metallochemistry. Journal of Inorganic Biochemistry. 99: 2403-22. PMID 16271394 DOI: 10.1016/J.Jinorgbio.2005.09.011 |
0.419 |
|
| 2005 |
Puglielli L, Friedlich AL, Setchell KD, Nagano S, Opazo C, Cherny RA, Barnham KJ, Wade JD, Melov S, Kovacs DM, Bush AI. Alzheimer disease beta-amyloid activity mimics cholesterol oxidase. The Journal of Clinical Investigation. 115: 2556-63. PMID 16127459 DOI: 10.1172/Jci23610 |
0.65 |
|
| 2005 |
Tucker S, Ahl M, Bush A, Westaway D, Huang X, Rogers JT. Pilot study of the reducing effect on amyloidosis in vivo by three FDA pre-approved drugs via the Alzheimer's APP 5' untranslated region. Current Alzheimer Research. 2: 249-54. PMID 15974925 DOI: 10.2174/1567205053585855 |
0.404 |
|
| 2005 |
Maynard CJ, Bush AI, Masters CL, Cappai R, Li QX. Metals and amyloid-beta in Alzheimer's disease. International Journal of Experimental Pathology. 86: 147-59. PMID 15910549 DOI: 10.1111/J.0959-9673.2005.00434.X |
0.58 |
|
| 2005 |
Cuajungco MP, Frederickson CJ, Bush AI. Amyloid-beta metal interaction and metal chelation. Sub-Cellular Biochemistry. 38: 235-54. PMID 15709482 DOI: 10.1007/0-387-23226-5_12 |
0.446 |
|
| 2005 |
Tickler AK, Smith DG, Ciccotosto GD, Tew DJ, Curtain CC, Carrington D, Masters CL, Bush AI, Cherny RA, Cappai R, Wade JD, Barnham KJ. Methylation of the imidazole side chains of the Alzheimer disease amyloid-beta peptide results in abolition of superoxide dismutase-like structures and inhibition of neurotoxicity. The Journal of Biological Chemistry. 280: 13355-63. PMID 15668252 DOI: 10.1074/Jbc.M414178200 |
0.506 |
|
| 2005 |
Ali FE, Separovic F, Barrow CJ, Cherny RA, Fraser F, Bush AI, Masters CL, Barnham KJ. Methionine regulates copper/hydrogen peroxide oxidation products of Abeta. Journal of Peptide Science : An Official Publication of the European Peptide Society. 11: 353-60. PMID 15635660 DOI: 10.1002/Psc.626 |
0.528 |
|
| 2005 |
Melov S, Wolf N, Strozyk D, Doctrow SR, Bush AI. Mice transgenic for Alzheimer disease beta-amyloid develop lens cataracts that are rescued by antioxidant treatment. Free Radical Biology & Medicine. 38: 258-61. PMID 15607908 DOI: 10.1016/J.Freeradbiomed.2004.10.023 |
0.48 |
|
| 2005 |
Friedlich AL, Bush AI. Copper and zinc in Alzheimer's disease and amyotrophic lateral sclerosis Neurodegenerative Diseases: Neurobiology, Pathogenesis and Therapeutics. 157-165. DOI: 10.1017/CBO9780511544873.014 |
0.313 |
|
| 2004 |
Venti A, Giordano T, Eder P, Bush AI, Lahiri DK, Greig NH, Rogers JT. The integrated role of desferrioxamine and phenserine targeted to an iron-responsive element in the APP-mRNA 5'-untranslated region. Annals of the New York Academy of Sciences. 1035: 34-48. PMID 15681799 DOI: 10.1196/Annals.1332.003 |
0.394 |
|
| 2004 |
Dedeoglu A, Cormier K, Payton S, Tseitlin KA, Kremsky JN, Lai L, Li X, Moir RD, Tanzi RE, Bush AI, Kowall NW, Rogers JT, Huang X. Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis. Experimental Gerontology. 39: 1641-9. PMID 15582280 DOI: 10.1016/J.Exger.2004.08.016 |
0.599 |
|
| 2004 |
Huang X, Atwood CS, Moir RD, Hartshorn MA, Tanzi RE, Bush AI. Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Abeta peptides. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 9: 954-60. PMID 15578276 DOI: 10.1007/S00775-004-0602-8 |
0.713 |
|
| 2004 |
Ritchie CW, Bush AI, Masters CL. Metal-protein attenuating compounds and Alzheimer's disease. Expert Opinion On Investigational Drugs. 13: 1585-92. PMID 15566316 DOI: 10.1517/13543784.13.12.1585 |
0.553 |
|
| 2004 |
Cerpa WF, BarrÃa MI, Chacón MA, Suazo M, González M, Opazo C, Bush AI, Inestrosa NC. The N-terminal copper-binding domain of the amyloid precursor protein protects against Cu2+ neurotoxicity in vivo. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1701-3. PMID 15345692 DOI: 10.1096/Fj.03-1349Fje |
0.315 |
|
| 2004 |
Ciccotosto GD, Tew D, Curtain CC, Smith D, Carrington D, Masters CL, Bush AI, Cherny RA, Cappai R, Barnham KJ. Enhanced toxicity and cellular binding of a modified amyloid beta peptide with a methionine to valine substitution. The Journal of Biological Chemistry. 279: 42528-34. PMID 15292164 DOI: 10.1074/Jbc.M406465200 |
0.515 |
|
| 2004 |
Barnham KJ, Haeffner F, Ciccotosto GD, Curtain CC, Tew D, Mavros C, Beyreuther K, Carrington D, Masters CL, Cherny RA, Cappai R, Bush AI. Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease beta-amyloid. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1427-9. PMID 15231727 DOI: 10.1096/Fj.04-1890Fje |
0.57 |
|
| 2004 |
Butterfield DA, Bush AI. Alzheimer's amyloid beta-peptide (1-42): involvement of methionine residue 35 in the oxidative stress and neurotoxicity properties of this peptide. Neurobiology of Aging. 25: 563-8. PMID 15172731 DOI: 10.1016/J.Neurobiolaging.2003.12.027 |
0.342 |
|
| 2004 |
Bush AI, Strozyk D. Serum copper: a biomarker for Alzheimer disease? Archives of Neurology. 61: 631-2. PMID 15148135 DOI: 10.1001/Archneur.61.5.631 |
0.42 |
|
| 2004 |
Yao S, Cherny RA, Bush AI, Masters CL, Barnham KJ. Characterizing bathocuproine self-association and subsequent binding to Alzheimer's disease amyloid beta-peptide by NMR. Journal of Peptide Science : An Official Publication of the European Peptide Society. 10: 210-7. PMID 15119593 DOI: 10.1002/Psc.539 |
0.506 |
|
| 2004 |
Huang X, Moir RD, Tanzi RE, Bush AI, Rogers JT. Redox-active metals, oxidative stress, and Alzheimer's disease pathology. Annals of the New York Academy of Sciences. 1012: 153-63. PMID 15105262 DOI: 10.1196/Annals.1306.012 |
0.61 |
|
| 2004 |
Friedlich AL, Lee JY, van Groen T, Cherny RA, Volitakis I, Cole TB, Palmiter RD, Koh JY, Bush AI. Neuronal zinc exchange with the blood vessel wall promotes cerebral amyloid angiopathy in an animal model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3453-9. PMID 15056725 DOI: 10.1523/Jneurosci.0297-04.2004 |
0.438 |
|
| 2004 |
Barnham KJ, Masters CL, Bush AI. Neurodegenerative diseases and oxidative stress. Nature Reviews. Drug Discovery. 3: 205-14. PMID 15031734 DOI: 10.1038/Nrd1330 |
0.439 |
|
| 2004 |
White AR, Barnham KJ, Huang X, Voltakis I, Beyreuther K, Masters CL, Cherny RA, Bush AI, Cappai R. Iron inhibits neurotoxicity induced by trace copper and biological reductants. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 9: 269-80. PMID 14758525 DOI: 10.1007/S00775-004-0521-8 |
0.512 |
|
| 2004 |
Nagano S, Huang X, Moir RD, Payton SM, Tanzi RE, Bush AI. Peroxidase activity of cyclooxygenase-2 (COX-2) cross-links beta-amyloid (Abeta) and generates Abeta-COX-2 hetero-oligomers that are increased in Alzheimer's disease. The Journal of Biological Chemistry. 279: 14673-8. PMID 14724276 DOI: 10.1074/Jbc.M313003200 |
0.585 |
|
| 2004 |
Atwood CS, Perry G, Zeng H, Kato Y, Jones WD, Ling KQ, Huang X, Moir RD, Wang D, Sayre LM, Smith MA, Chen SG, Bush AI. Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta. Biochemistry. 43: 560-8. PMID 14717612 DOI: 10.1021/Bi0358824 |
0.664 |
|
| 2004 |
Lee JY, Kim JH, Hong SH, Lee JY, Cherny RA, Bush AI, Palmiter RD, Koh JY. Estrogen decreases zinc transporter 3 expression and synaptic vesicle zinc levels in mouse brain. The Journal of Biological Chemistry. 279: 8602-7. PMID 14681234 DOI: 10.1074/Jbc.M309730200 |
0.342 |
|
| 2004 |
Barnham K, Cherny R, Cappai R, Melov S, Masters C, Bush A. Metal-Protein Attenuating Compounds (MPACs) for the Treatment of Alzheimers Disease Drug Design Reviews - Online. 1: 75-82. DOI: 10.2174/1567269043480690 |
0.483 |
|
| 2004 |
Opazo CR, Luza S, Volitakis I, Masters CL, Bush AI, Cherny R. P4-419 Clioquinol targets metallated abeta in human Alzheimer's and TG2576 mouse brains Neurobiology of Aging. 25: S593. DOI: 10.1016/S0197-4580(04)81975-4 |
0.509 |
|
| 2004 |
Rogers JT, Payton S, Greig NH, Jensen R, Cuny G, Lahiri DK, Morse LJ, Tanzi RE, Westaway D, Bush A, Gullans S, Sarang S, Huang X. P4-402 Alzheimer's disease drug discovery targeted to the APP MRNA 5′ untranslated region, a validated target Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81959-6 |
0.494 |
|
| 2004 |
Barnham KJ, Haeffner F, Ciccotosto GD, Curtain CC, Tew D, Masters CL, Cherny RA, Cappai R, Bush AI. P4-241 The mechanism by which Aβ produces hydrogen peroxide and its role in neurotoxicity Neurobiology of Aging. 25: S544. DOI: 10.1016/S0197-4580(04)81799-8 |
0.431 |
|
| 2004 |
Ciccotosto GD, Curtain CC, Tew D, Carrington D, Masters CL, Cherny RA, Bush AI, Cappai R, Barnham KJ. P3-187 Mutagenesis-toxicity studies of the amyloid beta peptide of Alzheimer's disease Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81339-3 |
0.532 |
|
| 2004 |
Goldstein LE, Hartley DM, Moir RD, Blakely EA, Chang PI, Marcus MA, Martin-Rehrmann M, Ko G, Ericsson MH, Huang X, Tanzi RE, Bush AI, Chylack LT. P1-131 (Aβ) in human lens & aqueous humor: further characterization of a novel AD biomarker Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80454-8 |
0.539 |
|
| 2004 |
Bush AI. S4-02-06 Copper and zinc in Alzheimer's disease: from bench to clinic Neurobiology of Aging. 25: S69-S70. DOI: 10.1016/S0197-4580(04)80236-7 |
0.412 |
|
| 2003 |
Ritchie CW, Bush AI, Mackinnon A, Macfarlane S, Mastwyk M, MacGregor L, Kiers L, Cherny R, Li QX, Tammer A, Carrington D, Mavros C, Volitakis I, Xilinas M, Ames D, et al. Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial. Archives of Neurology. 60: 1685-91. PMID 14676042 DOI: 10.1001/Archneur.60.12.1685 |
0.649 |
|
| 2003 |
Bush AI. Copper, zinc, and the metallobiology of Alzheimer disease. Alzheimer Disease and Associated Disorders. 17: 147-50. PMID 14512827 DOI: 10.1097/00002093-200307000-00005 |
0.436 |
|
| 2003 |
Bush AI, Masters CL, Tanzi RE. Copper, beta-amyloid, and Alzheimer's disease: tapping a sensitive connection. Proceedings of the National Academy of Sciences of the United States of America. 100: 11193-4. PMID 14506299 DOI: 10.1073/Pnas.2135061100 |
0.665 |
|
| 2003 |
Barnham KJ, Ciccotosto GD, Tickler AK, Ali FE, Smith DG, Williamson NA, Lam YH, Carrington D, Tew D, Kocak G, Volitakis I, Separovic F, Barrow CJ, Wade JD, Masters CL, ... ... Bush AI, et al. Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation. The Journal of Biological Chemistry. 278: 42959-65. PMID 12925530 DOI: 10.1074/Jbc.M305494200 |
0.534 |
|
| 2003 |
Finefrock AE, Bush AI, Doraiswamy PM. Current status of metals as therapeutic targets in Alzheimer's disease. Journal of the American Geriatrics Society. 51: 1143-8. PMID 12890080 DOI: 10.1046/J.1532-5415.2003.51368.X |
0.452 |
|
| 2003 |
Goldstein LE, Muffat JA, Cherny RA, Moir RD, Ericsson MH, Huang X, Mavros C, Coccia JA, Faget KY, Fitch KA, Masters CL, Tanzi RE, Chylack LT, Bush AI. Cytosolic beta-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease. Lancet. 361: 1258-65. PMID 12699953 DOI: 10.1016/S0140-6736(03)12981-9 |
0.815 |
|
| 2003 |
Bush AI. The metallobiology of Alzheimer's disease. Trends in Neurosciences. 26: 207-14. PMID 12689772 DOI: 10.1016/S0166-2236(03)00067-5 |
0.484 |
|
| 2003 |
Kaur D, Yantiri F, Rajagopalan S, Kumar J, Mo JQ, Boonplueang R, Viswanath V, Jacobs R, Yang L, Beal MF, DiMonte D, Volitaskis I, Ellerby L, Cherny RA, Bush AI, et al. Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's disease. Neuron. 37: 899-909. PMID 12670420 DOI: 10.1016/S0896-6273(03)00126-0 |
0.32 |
|
| 2003 |
Curtain CC, Ali FE, Smith DG, Bush AI, Masters CL, Barnham KJ. Metal ions, pH, and cholesterol regulate the interactions of Alzheimer's disease amyloid-beta peptide with membrane lipid. The Journal of Biological Chemistry. 278: 2977-82. PMID 12435742 DOI: 10.1074/Jbc.M205455200 |
0.447 |
|
| 2003 |
Curtain C, Barnham K, Bush A. Aβ Metallobiology and the Development of Novel Metal-Protein Attenuating Compounds (MPACs) for Alzheimers Disease Current Medicinal Chemistry-Immunology, Endocrine & Metabolic Agents. 3: 309-315. DOI: 10.2174/1568013033483276 |
0.49 |
|
| 2003 |
Cherny R, Masters C, Bush A. The Medicinal Metallochemistry of Alzheimers Disease Current Medicinal Chemistry-Immunology, Endocrine & Metabolic Agents. 3: 9-13. DOI: 10.2174/1568013033358626 |
0.519 |
|
| 2003 |
Bush AI. Beta-amyloid cuproprotein: a therapeutic target for alzheimer's disease Journal of Inorganic Biochemistry. 96: 43. DOI: 10.1016/S0162-0134(03)80478-6 |
0.427 |
|
| 2003 |
Ciccotosto GD, Barnham KJ, Cherny RA, Masters CL, Bush AI, Curtain CC, Cappai R, Tew D. Methionine oxidation: Implications for the mechanism of toxicity of the β-amyloid peptide from Alzheimer's disease International Journal of Peptide Research and Therapeutics. 10: 413-417. DOI: 10.1007/S10989-004-2394-7 |
0.515 |
|
| 2003 |
Ciccotosto GD, Barnham KJ, Cherny RA, Masters CL, Bush AI, Curtain CC, Cappai R, Tew D. Methionine oxidation: Implications for the mechanism of toxicity of the β-amyloid peptide from Alzheimer's disease Letters in Peptide Science. 10: 413-417. DOI: 10.1007/BF02442572 |
0.439 |
|
| 2002 |
Bush AI. Metal complexing agents as therapies for Alzheimer's disease. Neurobiology of Aging. 23: 1031-8. PMID 12470799 DOI: 10.1016/S0197-4580(02)00120-3 |
0.476 |
|
| 2002 |
Maynard CJ, Cappai R, Volitakis I, Cherny RA, White AR, Beyreuther K, Masters CL, Bush AI, Li QX. Overexpression of Alzheimer's disease amyloid-beta opposes the age-dependent elevations of brain copper and iron. The Journal of Biological Chemistry. 277: 44670-6. PMID 12215434 DOI: 10.1074/Jbc.M204379200 |
0.58 |
|
| 2002 |
Rogers JT, Randall JD, Eder PS, Huang X, Bush AI, Tanzi RE, Venti A, Payton SM, Giordano T, Nagano S, Cahill CM, Moir R, Lahiri DK, Greig N, Sarang SS, et al. Alzheimer's disease drug discovery targeted to the APP mRNA 5'untranslated region. Journal of Molecular Neuroscience : Mn. 19: 77-82. PMID 12212798 DOI: 10.1007/S12031-002-0014-6 |
0.517 |
|
| 2002 |
Rogers JT, Randall JD, Cahill CM, Eder PS, Huang X, Gunshin H, Leiter L, McPhee J, Sarang SS, Utsuki T, Greig NH, Lahiri DK, Tanzi RE, Bush AI, Giordano T, et al. An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript. The Journal of Biological Chemistry. 277: 45518-28. PMID 12198135 DOI: 10.1074/Jbc.M207435200 |
0.508 |
|
| 2002 |
Opazo C, Huang X, Cherny RA, Moir RD, Roher AE, White AR, Cappai R, Masters CL, Tanzi RE, Inestrosa NC, Bush AI. Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2). The Journal of Biological Chemistry. 277: 40302-8. PMID 12192006 DOI: 10.1074/Jbc.M206428200 |
0.597 |
|
| 2002 |
Bush AI, Tanzi RE. The galvanization of beta-amyloid in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 99: 7317-9. PMID 12032279 DOI: 10.1073/Pnas.122249699 |
0.576 |
|
| 2002 |
Bush A. Response: '… and C is for Clioquinol' - the AβCs of Alzheimer's disease Trends in Neurosciences. 25: 123-124. DOI: 10.1016/S0166-2236(02)02085-4 |
0.378 |
|
| 2001 |
Jobling MF, Huang X, Stewart LR, Barnham KJ, Curtain C, Volitakis I, Perugini M, White AR, Cherny RA, Masters CL, Barrow CJ, Collins SJ, Bush AI, Cappai R. Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106-126. Biochemistry. 40: 8073-84. PMID 11434776 DOI: 10.1021/Bi0029088 |
0.491 |
|
| 2001 |
Cherny RA, Atwood CS, Xilinas ME, Gray DN, Jones WD, McLean CA, Barnham KJ, Volitakis I, Fraser FW, Kim Y, Huang X, Goldstein LE, Moir RD, Lim JT, Beyreuther K, ... ... Bush AI, et al. Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice. Neuron. 30: 665-76. PMID 11430801 DOI: 10.1016/S0896-6273(01)00317-8 |
0.742 |
|
| 2001 |
Bush AI, Goldstein LE. Specific metal-catalysed protein oxidation reactions in chronic degenerative disorders of ageing: focus on Alzheimer's disease and age-related cataracts. Novartis Foundation Symposium. 235: 26-38; discussion 38. PMID 11280030 DOI: 10.1002/0470868694.Ch4 |
0.402 |
|
| 2001 |
Curtain CC, Ali F, Volitakis I, Cherny RA, Norton RS, Beyreuther K, Barrow CJ, Masters CL, Bush AI, Barnham KJ. Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits. The Journal of Biological Chemistry. 276: 20466-73. PMID 11274207 DOI: 10.1074/Jbc.M100175200 |
0.55 |
|
| 2001 |
White AR, Huang X, Jobling MF, Barrow CJ, Beyreuther K, Masters CL, Bush AI, Cappai R. Homocysteine potentiates copper- and amyloid beta peptide-mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's-type neurodegenerative pathways. Journal of Neurochemistry. 76: 1509-20. PMID 11238735 DOI: 10.1046/J.1471-4159.2001.00178.X |
0.494 |
|
| 2001 |
Rottkamp CA, Raina AK, Zhu X, Gaier E, Bush AI, Atwood CS, Chevion M, Perry G, Smith MA. Redox-active iron mediates amyloid-beta toxicity. Free Radical Biology & Medicine. 30: 447-50. PMID 11182300 DOI: 10.1016/S0891-5849(00)00494-9 |
0.655 |
|
| 2001 |
Bush AI. Therapeutic targets in the biology of Alzheimer's disease Current Opinion in Psychiatry. 14: 341-348. DOI: 10.1097/00001504-200107000-00018 |
0.358 |
|
| 2000 |
Bush AI, Atwood CS, Goldstein LE, Huang X, Rogers J. Could Abeta and AbetaPP be Antioxidants? Journal of Alzheimer's Disease : Jad. 2: 83-84. PMID 12214093 DOI: 10.3233/Jad-2000-2203 |
0.585 |
|
| 2000 |
Cuajungco MP, Fagét KY, Huang X, Tanzi RE, Bush AI. Metal chelation as a potential therapy for Alzheimer's disease. Annals of the New York Academy of Sciences. 920: 292-304. PMID 11193167 DOI: 10.1111/J.1749-6632.2000.Tb06938.X |
0.582 |
|
| 2000 |
Lynch T, Cherny RA, Bush AI. Oxidative processes in Alzheimer's disease: the role of abeta-metal interactions. Experimental Gerontology. 35: 445-51. PMID 10959032 DOI: 10.1016/S0531-5565(00)00112-1 |
0.487 |
|
| 2000 |
Cherny RA, Barnham KJ, Lynch T, Volitakis I, Li QX, McLean CA, Multhaup G, Beyreuther K, Tanzi RE, Masters CL, Bush AI. Chelation and intercalation: complementary properties in a compound for the treatment of Alzheimer's disease. Journal of Structural Biology. 130: 209-16. PMID 10940226 DOI: 10.1006/Jsbi.2000.4285 |
0.659 |
|
| 2000 |
Atwood CS, Scarpa RC, Huang X, Moir RD, Jones WD, Fairlie DP, Tanzi RE, Bush AI. Characterization of copper interactions with alzheimer amyloid beta peptides: identification of an attomolar-affinity copper binding site on amyloid beta1-42. Journal of Neurochemistry. 75: 1219-33. PMID 10936205 DOI: 10.1046/J.1471-4159.2000.0751219.X |
0.677 |
|
| 2000 |
Atwood CS, Huang X, Khatri A, Scarpa RC, Kim YS, Moir RD, Tanzi RE, Roher AE, Bush AI. Copper catalyzed oxidation of Alzheimer Abeta. Cellular and Molecular Biology (Noisy-Le-Grand, France). 46: 777-83. PMID 10875439 |
0.664 |
|
| 2000 |
Goldstein LE, Leopold MC, Huang X, Atwood CS, Saunders AJ, Hartshorn M, Lim JT, Faget KY, Muffat JA, Scarpa RC, Chylack LT, Bowden EF, Tanzi RE, Bush AI. 3-Hydroxykynurenine and 3-hydroxyanthranilic acid generate hydrogen peroxide and promote alpha-crystallin cross-linking by metal ion reduction. Biochemistry. 39: 7266-75. PMID 10852726 DOI: 10.1021/Bi992997S |
0.773 |
|
| 2000 |
Huang X, Cuajungco MP, Atwood CS, Moir RD, Tanzi RE, Bush AI. Alzheimer's disease, beta-amyloid protein and zinc. The Journal of Nutrition. 130: 1488S-92S. PMID 10801964 DOI: 10.1093/Jn/130.5.1488S |
0.729 |
|
| 2000 |
Cuajungco MP, Goldstein LE, Nunomura A, Smith MA, Lim JT, Atwood CS, Huang X, Farrag YW, Perry G, Bush AI. Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc. The Journal of Biological Chemistry. 275: 19439-42. PMID 10801774 DOI: 10.1074/jbc.C000165200 |
0.667 |
|
| 2000 |
Bush AI. Metals and neuroscience. Current Opinion in Chemical Biology. 4: 184-91. PMID 10742195 DOI: 10.1016/S1367-5931(99)00073-3 |
0.421 |
|
| 2000 |
Cuajungco MP, Atwood CS, Huang X, Lynch T, Cherny RA, Perry G, Bush AI. Competitive regulation of aβredox activity by copper and zinc: Parallels in the pathogenetic mechanisms of Alzheimer's disease and familial amyotrophic lateral sclerosis Neurobiology of Aging. 21: 62. DOI: 10.1016/S0197-4580(00)82501-4 |
0.655 |
|
| 2000 |
Huang X, Moir RD, Atwood CS, Goldstein LE, Tanzi RE, Bush AI. Enhanced redox interaction of copper-Aβ by homocysteine Neurobiology of Aging. 21: 62. DOI: 10.1016/S0197-4580(00)82500-2 |
0.658 |
|
| 2000 |
Atwood CS, Moir RD, Jones WD, Huang X, Perry G, Tanzi RE, Roher AE, Bush AI. Human amyloid-derived aßcontains tyrosine cross-linked oligomers Neurobiology of Aging. 21: 199. DOI: 10.1016/S0197-4580(00)82237-X |
0.678 |
|
| 1999 |
Cuajungco MP, Lees GJ, Kydd RR, Tanzi RE, Bush AI. Zinc and Alzheimer's Disease: An Update. Nutritional Neuroscience. 2: 191-208. PMID 27415572 DOI: 10.1080/1028415X.1999.11747277 |
0.607 |
|
| 1999 |
Huang X, Cuajungco MP, Atwood CS, Hartshorn MA, Tyndall JD, Hanson GR, Stokes KC, Leopold M, Multhaup G, Goldstein LE, Scarpa RC, Saunders AJ, Lim J, Moir RD, Glabe C, ... ... Bush AI, et al. Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction. The Journal of Biological Chemistry. 274: 37111-6. PMID 10601271 DOI: 10.1074/Jbc.274.52.37111 |
0.731 |
|
| 1999 |
McLean CA, Cherny RA, Fraser FW, Fuller SJ, Smith MJ, Beyreuther K, Bush AI, Masters CL. Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Annals of Neurology. 46: 860-6. PMID 10589538 DOI: 10.1002/1531-8249(199912)46:6<860::Aid-Ana8>3.0.Co;2-M |
0.569 |
|
| 1999 |
White AR, Multhaup G, Maher F, Bellingham S, Camakaris J, Zheng H, Bush AI, Beyreuther K, Masters CL, Cappai R. The Alzheimer's disease amyloid precursor protein modulates copper-induced toxicity and oxidative stress in primary neuronal cultures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 9170-9. PMID 10531420 DOI: 10.1523/Jneurosci.19-21-09170.1999 |
0.499 |
|
| 1999 |
White AR, Reyes R, Mercer JF, Camakaris J, Zheng H, Bush AI, Multhaup G, Beyreuther K, Masters CL, Cappai R. Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice. Brain Research. 842: 439-44. PMID 10526140 DOI: 10.1016/S0006-8993(99)01861-2 |
0.545 |
|
| 1999 |
Cherny RA, Legg JT, McLean CA, Fairlie DP, Huang X, Atwood CS, Beyreuther K, Tanzi RE, Masters CL, Bush AI. Aqueous dissolution of Alzheimer's disease Abeta amyloid deposits by biometal depletion. The Journal of Biological Chemistry. 274: 23223-8. PMID 10438495 DOI: 10.1074/Jbc.274.33.23223 |
0.72 |
|
| 1999 |
Moir RD, Atwood CS, Huang X, Tanzi RE, Bush AI. Mounting evidence for the involvement of zinc and copper in Alzheimer's disease. European Journal of Clinical Investigation. 29: 569-70. PMID 10411660 DOI: 10.1046/j.1365-2362.1999.00472.x |
0.675 |
|
| 1999 |
Huang X, Atwood CS, Hartshorn MA, Multhaup G, Goldstein LE, Scarpa RC, Cuajungco MP, Gray DN, Lim J, Moir RD, Tanzi RE, Bush AI. The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction. Biochemistry. 38: 7609-16. PMID 10386999 DOI: 10.1021/Bi990438F |
0.667 |
|
| 1999 |
Li QX, Maynard C, Cappai R, McLean CA, Cherny RA, Lynch T, Culvenor JG, Trevaskis J, Tanner JE, Bailey KA, Czech C, Bush AI, Beyreuther K, Masters CL. Intracellular accumulation of detergent-soluble amyloidogenic A beta fragment of Alzheimer's disease precursor protein in the hippocampus of aged transgenic mice. Journal of Neurochemistry. 72: 2479-87. PMID 10349858 DOI: 10.1046/J.1471-4159.1999.0722479.X |
0.455 |
|
| 1999 |
White AR, Bush AI, Beyreuther K, Masters CL, Cappai R. Exacerbation of copper toxicity in primary neuronal cultures depleted of cellular glutathione. Journal of Neurochemistry. 72: 2092-8. PMID 10217289 DOI: 10.1046/J.1471-4159.1999.0722092.X |
0.494 |
|
| 1999 |
Moir RD, Atwood CS, Romano DM, Laurans MH, Huang X, Bush AI, Smith JD, Tanzi RE. Differential effects of apolipoprotein E isoforms on metal-induced aggregation of A beta using physiological concentrations. Biochemistry. 38: 4595-603. PMID 10194381 DOI: 10.1021/Bi982437D |
0.678 |
|
| 1999 |
Atwood CS, Huang X, Moir RD, Tanzi RE, Bush AI. Role of free radicals and metal ions in the pathogenesis of Alzheimer's disease. Metal Ions in Biological Systems. 36: 309-64. PMID 10093929 DOI: 10.1201/9780203747605-10 |
0.662 |
|
| 1999 |
Doraiswamy PM, Sunderland T, Bush AI, Klunk WE, Sheline YI. EARLY RECOGNITION AND TREATMENT OF ALZHEIMER's DISEASE: WHAT's NEW? WHAT's CONTROVERSIAL? WHAT's PRACTICAL? The American Journal of Geriatric Psychiatry. 7: 3. DOI: 10.1097/00019442-199911001-00006 |
0.342 |
|
| 1998 |
Wolozin B, Maheshwari S, Jones C, Dukoff R, Wallace W, Racchi M, Nagula S, Shulman NR, Sunderland T, Bush A. Beta-amyloid augments platelet aggregation: reduced activity of familial angiopathy-associated mutants. Molecular Psychiatry. 3: 500-7. PMID 9857975 DOI: 10.1038/Sj.Mp.4000451 |
0.38 |
|
| 1998 |
Bush AI, Tanzi RE. Alzheimer disease-related abnormalities of amyloid beta precursor protein isoforms in the platelet: the brain's delegate in the periphery? Archives of Neurology. 55: 1179-80. PMID 9740110 DOI: 10.1001/Archneur.55.9.1179 |
0.574 |
|
| 1998 |
Atwood CS, Moir RD, Huang X, Scarpa RC, Bacarra NM, Romano DM, Hartshorn MA, Tanzi RE, Bush AI. Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis. The Journal of Biological Chemistry. 273: 12817-26. PMID 9582309 DOI: 10.1074/Jbc.273.21.12817 |
0.685 |
|
| 1998 |
Moir RD, Lynch T, Bush AI, Whyte S, Henry A, Portbury S, Multhaup G, Small DH, Tanzi RE, Beyreuther K, Masters CL. Relative increase in Alzheimer's disease of soluble forms of cerebral Abeta amyloid protein precursor containing the Kunitz protease inhibitory domain. The Journal of Biological Chemistry. 273: 5013-9. PMID 9478949 DOI: 10.1074/Jbc.273.9.5013 |
0.642 |
|
| 1997 |
Huang X, Atwood CS, Moir RD, Hartshorn MA, Vonsattel JP, Tanzi RE, Bush AI. Zinc-induced Alzheimer's Abeta1-40 aggregation is mediated by conformational factors. The Journal of Biological Chemistry. 272: 26464-70. PMID 9334223 DOI: 10.1074/Jbc.272.42.26464 |
0.698 |
|
| 1997 |
Aschner M, Cherian MG, Klaassen CD, Palmiter RD, Erickson JC, Bush AI. Metallothioneins in brain--the role in physiology and pathology. Toxicology and Applied Pharmacology. 142: 229-42. PMID 9070344 DOI: 10.1006/Taap.1996.8054 |
0.305 |
|
| 1996 |
Atwood C, Moir R, Huang X, Bacarra N, Margo L, Glabe C, Tanzi R, Bush A. 527 Modulation of Aβ and mutant aggregation in vitro by zinc and pH Neurobiology of Aging. 17: S131. DOI: 10.1016/S0197-4580(96)80529-X |
0.638 |
|
| 1996 |
Bush A, Atwood C, Huang X, Moir R, Glabe C, Tanzi R. Abnormal homeostasis of pH and Zinc: The prelude for cerebral Aβ amyloid formation? European Neuropsychopharmacology. 6: 20. DOI: 10.1016/S0197-4580(96)80524-0 |
0.666 |
|
| 1996 |
Bush A, Atwood C, Huang X, Moir R, Glabe C, Tanzi R. 522 Abnormal homeostasis of pH and zinc: The prelude for cerebral Aβ amyloid formation? Neurobiology of Aging. 17: S130. DOI: 10.1016/S0197-4580(96)80524-0 |
0.554 |
|
| 1995 |
Kounnas MZ, Moir RD, Rebeck GW, Bush AI, Argraves WS, Tanzi RE, Hyman BT, Strickland DK. LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted beta-amyloid precursor protein and mediates its degradation. Cell. 82: 331-40. PMID 7543026 DOI: 10.1016/0092-8674(95)90320-8 |
0.54 |
|
| 1994 |
Bush AI, Pettingell WH, Paradis MD, Tanzi RE. Modulation of A beta adhesiveness and secretase site cleavage by zinc. The Journal of Biological Chemistry. 269: 12152-8. PMID 8163520 |
0.445 |
|
| 1994 |
Bush AI, Pettingell WH, Multhaup G, d Paradis M, Vonsattel JP, Gusella JF, Beyreuther K, Masters CL, Tanzi RE. Rapid induction of Alzheimer A beta amyloid formation by zinc. Science (New York, N.Y.). 265: 1464-7. PMID 8073293 DOI: 10.1126/Science.8073293 |
0.682 |
|
| 1994 |
Li QX, Berndt MC, Bush AI, Rumble B, Mackenzie I, Friedhuber A, Beyreuther K, Masters CL. Membrane-associated forms of the beta A4 amyloid protein precursor of Alzheimer's disease in human platelet and brain: surface expression on the activated human platelet. Blood. 84: 133-42. PMID 8018913 DOI: 10.1182/Blood.V84.1.133.Bloodjournal841133 |
0.371 |
|
| 1994 |
Multhaup G, Bush AI, Pollwein P, Masters CL. Interaction between the zinc (II) and the heparin binding site of the Alzheimer's disease beta A4 amyloid precursor protein (APP). Febs Letters. 355: 151-4. PMID 7982489 DOI: 10.1016/0014-5793(94)01176-1 |
0.491 |
|
| 1994 |
Bush AI, Pettingell WH, de Paradis M, Tanzi RE, Wasco W. The amyloid beta-protein precursor and its mammalian homologues. Evidence for a zinc-modulated heparin-binding superfamily. The Journal of Biological Chemistry. 269: 26618-21. PMID 7929392 |
0.694 |
|
| 1994 |
Tanzi RE, Bush AI, Wasco W. Genetic studies of Alzheimer's disease: lessons learned and future imperatives. Neurobiology of Aging. 15: S145-8. PMID 7700440 DOI: 10.1016/0197-4580(94)90193-7 |
0.707 |
|
| 1993 |
Bush AI, Beyreuther K, Masters CL. The beta A4 amyloid protein precursor in human circulation. Annals of the New York Academy of Sciences. 695: 175-82. PMID 8239279 DOI: 10.1111/J.1749-6632.1993.Tb23048.X |
0.523 |
|
| 1993 |
Tanzi R, Gaston S, Bush A, Romano D, Pettingell W, Peppercorn J, Paradis M, Gurubhagavatula S, Jenkins B, Wasco W. Genetic heterogeneity of gene defects responsible for familial Alzheimer disease. Genetica. 91: 255-63. PMID 8125274 DOI: 10.1007/Bf01436002 |
0.691 |
|
| 1992 |
Bush AI, Whyte S, Thomas LD, Williamson TG, Van Tiggelen CJ, Currie J, Small DH, Moir RD, Li QX, Rumble B. An abnormality of plasma amyloid protein precursor in Alzheimer's disease. Annals of Neurology. 32: 57-65. PMID 1642473 DOI: 10.1002/Ana.410320110 |
0.465 |
|
| 1992 |
Moir RD, Martins RN, Bush AI, Small DH, Milward EA, Rumble BA, Multhaup G, Beyreuther K, Masters CL. Human brain beta A4 amyloid protein precursor of Alzheimer's disease: purification and partial characterization. Journal of Neurochemistry. 59: 1490-8. PMID 1402900 DOI: 10.1111/J.1471-4159.1992.Tb08465.X |
0.618 |
|
| 1992 |
Bush AI, Beyreuther K, Masters CL. Beta A4 amyloid protein and its precursor in Alzheimer's disease. Pharmacology & Therapeutics. 56: 97-117. PMID 1297146 DOI: 10.1016/0163-7258(92)90039-3 |
0.532 |
|
| 1992 |
Bush A, Williamson T, Moir R, Li Q, Currie J, Small D, Rumble B, Mönning U, Beyreuther K, Masters C. Plasma amyloid precursor protein is a marker for alzheimer’s disease Pathology. 24: 24. DOI: 10.1016/S0031-3025(16)35969-4 |
0.542 |
|
| 1992 |
Rumble B, Small D, Moir R, Bush A, Masters C, Beyreuther K. Plasma kallikrein may process the amyloid protein precursor of alzheimer’s disease Pathology. 24: 24. DOI: 10.1016/S0031-3025(16)35968-2 |
0.534 |
|
| 1992 |
Li O, Bush A, Mackenzie I, Friedhuber A, Beyreuther K, Masters C. Characterization of a membrane bound form of the amyloid protein precursor (APP) of alzheimer’s disease Pathology. 24: 9. DOI: 10.1016/S0031-3025(16)35914-1 |
0.45 |
|
| 1992 |
Whyte S, Bush AI, Currie J, Williamson TG, Tiggelen CJV, Small DH, Moir RD, Rumble B, Thomas LD, Li Q, Mönning U, Beyreuther K, Masters CL. The abnormality of plasma amyloid protein precursor in Alzheimer's disease Neurobiology of Aging. 13. DOI: 10.1016/0197-4580(92)90241-O |
0.546 |
|
| 1992 |
Multhaup G, Bush AI, Pollwein P, Masters CL, Beyreuther K. Specific binding of the alzheimer βA4 amyloid precursor to collagen, laminin, and heparin Journal of Protein Chemistry. 11: 398-399. DOI: 10.1007/Bf01673756 |
0.51 |
|
| 1991 |
Beyreuther K, Bush AI, Dyrks T, Hilbich C, König G, Mönning U, Multhaup G, Prior R, Rumble B, Schubert W. Mechanisms of amyloid deposition in Alzheimer's disease. Annals of the New York Academy of Sciences. 640: 129-39. PMID 1776729 DOI: 10.1111/J.1749-6632.1991.Tb00204.X |
0.459 |
|
| 1991 |
Small DH, Moir RD, Fuller SJ, Michaelson S, Bush AI, Li QX, Milward E, Hilbich C, Weidemann A, Beyreuther K. A protease activity associated with acetylcholinesterase releases the membrane-bound form of the amyloid protein precursor of Alzheimer's disease. Biochemistry. 30: 10795-9. PMID 1718425 DOI: 10.1021/Bi00108A027 |
0.447 |
|
| 1990 |
Masters CL, Bush A, Evin G, Fuller S, Li Q, Mackenzie I, Milward E, Moir R, Small D, Beyreuther K. The βA4 amyloid protein and its precursors as biological markers for Alzheimer's disease Neurobiology of Aging. 11: 330-331. DOI: 10.1016/0197-4580(90)90874-Y |
0.561 |
|
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