Tim Dunn, Ph.D. - Publications

Harvard University, Cambridge, MA, United States 

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Naumann EA, Fitzgerald JE, Dunn TW, Rihel J, Sompolinsky H, Engert F. From Whole-Brain Data to Functional Circuit Models: The Zebrafish Optomotor Response. Cell. 167: 947-960.e20. PMID 27814522 DOI: 10.1016/j.cell.2016.10.019  0.64
2016 Dunn TW, Mu Y, Narayan S, Randlett O, Naumann EA, Yang CT, Schier AF, Freeman J, Engert F, Ahrens MB. Brain-wide mapping of neural activity controlling zebrafish exploratory locomotion. Elife. 5. PMID 27003593 DOI: 10.7554/eLife.12741  0.8
2016 Dunn TW, Gebhardt C, Naumann EA, Riegler C, Ahrens MB, Engert F, Del Bene F. Neural Circuits Underlying Visually Evoked Escapes in Larval Zebrafish. Neuron. PMID 26804997 DOI: 10.1016/j.neuron.2015.12.021  0.8
2016 Kennedy MA, Moffat TC, Gable K, Ganesan S, Niewola-Staszkowska K, Johnston A, Nislow C, Giaever G, Harris LJ, Loewith R, Zaremberg V, Harper ME, Dunn T, Bennett SA, Baetz K. A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction. Scientific Reports. 6: 19332. PMID 26757638 DOI: 10.1038/srep19332  0.44
2015 Chauhan N, Han G, Somashekarappa N, Gable K, Dunn T, Kohlwein SD. Regulation of sphingolipid biosynthesis by the morphogenesis checkpoint kinase Swe1. The Journal of Biological Chemistry. PMID 26634277 DOI: 10.1074/jbc.M115.693200  0.44
2015 Zhao L, Spassieva S, Gable K, Gupta SD, Shi LY, Wang J, Bielawski J, Hicks WL, Krebs MP, Naggert J, Hannun YA, Dunn TM, Nishina PM. Elevation of 20-carbon long chain bases due to a mutation in serine palmitoyltransferase small subunit b results in neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 26438849 DOI: 10.1073/pnas.1516733112  0.44
2015 Siow D, Sunkara M, Dunn TM, Morris AJ, Wattenberg B. ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis. Journal of Lipid Research. 56: 898-908. PMID 25691431 DOI: 10.1194/jlr.M057539  0.44
2015 Gupta SD, Gable K, Alexaki A, Chandris P, Proia RL, Dunn TM, Harmon JM. Expression of the ORMDLS, modulators of serine palmitoyltransferase, is regulated by sphingolipids in mammalian cells. The Journal of Biological Chemistry. 290: 90-8. PMID 25395622 DOI: 10.1074/jbc.M114.588236  0.44
2014 Alexaki A, Gupta SD, Majumder S, Kono M, Tuymetova G, Harmon JM, Dunn TM, Proia RL. Autophagy regulates sphingolipid levels in the liver. Journal of Lipid Research. 55: 2521-31. PMID 25332431 DOI: 10.1194/jlr.M051862  0.44
2014 Kennedy MA, Gable K, Niewola-Staszkowska K, Abreu S, Johnston A, Harris LJ, Reggiori F, Loewith R, Dunn T, Bennett SA, Baetz K. A neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeast. Plos Genetics. 10: e1004010. PMID 24465216 DOI: 10.1371/journal.pgen.1004010  0.44
2014 Feenstra H, Dunn T, Lewis D, Herrera K, Foroutan J, Calabio R, Batey A, Wang E, Gebbia JA. Complexity of noninvasive prenatal screening and diagnostic testing for an unbalanced translocation involving chromosomes 5 and 18. Prenatal Diagnosis. 34: 195-8. PMID 24214723 DOI: 10.1002/pd.4270  0.44
2013 Zimmermann C, Santos A, Gable K, Epstein S, Gururaj C, Chymkowitch P, Pultz D, Rødkær SV, Clay L, BjørÃ¥s M, Barral Y, Chang A, Færgeman NJ, Dunn TM, Riezman H, et al. TORC1 inhibits GSK3-mediated Elo2 phosphorylation to regulate very long chain fatty acid synthesis and autophagy. Cell Reports. 5: 1036-46. PMID 24239358 DOI: 10.1016/j.celrep.2013.10.024  0.44
2013 Kimberlin AN, Majumder S, Han G, Chen M, Cahoon RE, Stone JM, Dunn TM, Cahoon EB. Arabidopsis 56-amino acid serine palmitoyltransferase-interacting proteins stimulate sphingolipid synthesis, are essential, and affect mycotoxin sensitivity. The Plant Cell. 25: 4627-39. PMID 24214397 DOI: 10.1105/tpc.113.116145  0.44
2013 Beattie AE, Gupta SD, Frankova L, Kazlauskaite A, Harmon JM, Dunn TM, Campopiano DJ. The pyridoxal 5'-phosphate (PLP)-dependent enzyme serine palmitoyltransferase (SPT): effects of the small subunits and insights from bacterial mimics of human hLCB2a HSAN1 mutations. Biomed Research International. 2013: 194371. PMID 24175284 DOI: 10.1155/2013/194371  0.44
2013 Wadsworth JM, Clarke DJ, McMahon SA, Lowther JP, Beattie AE, Langridge-Smith PR, Broughton HB, Dunn TM, Naismith JH, Campopiano DJ. The chemical basis of serine palmitoyltransferase inhibition by myriocin. Journal of the American Chemical Society. 135: 14276-85. PMID 23957439 DOI: 10.1021/ja4059876  0.44
2013 Huang KH, Ahrens MB, Dunn TW, Engert F. Spinal projection neurons control turning behaviors in zebrafish. Current Biology : Cb. 23: 1566-73. PMID 23910662 DOI: 10.1016/j.cub.2013.06.044  0.8
2013 Keitges EA, Pasion R, Burnside RD, Mason C, Gonzalez-Ruiz A, Dunn T, Masiello M, Gebbia JA, Fernandez CO, Risheg H. Prenatal diagnosis of two fetuses with deletions of 8p23.1, critical region for congenital diaphragmatic hernia and heart defects. American Journal of Medical Genetics. Part A. 161: 1755-8. PMID 23696316 DOI: 10.1002/ajmg.a.35965  0.44
2013 Markham JE, Lynch DV, Napier JA, Dunn TM, Cahoon EB. Plant sphingolipids: function follows form. Current Opinion in Plant Biology. 16: 350-7. PMID 23499054 DOI: 10.1016/j.pbi.2013.02.009  0.44
2013 Kokel D, Dunn TW, Ahrens MB, Alshut R, Cheung CY, Saint-Amant L, Bruni G, Mateus R, van Ham TJ, Shiraki T, Fukada Y, Kojima D, Yeh JR, Mikut R, von Lintig J, et al. Identification of nonvisual photomotor response cells in the vertebrate hindbrain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3834-43. PMID 23447595 DOI: 10.1523/JNEUROSCI.3689-12.2013  0.8
2013 Harmon JM, Bacikova D, Gable K, Gupta SD, Han G, Sengupta N, Somashekarappa N, Dunn TM. Topological and functional characterization of the ssSPTs, small activating subunits of serine palmitoyltransferase. The Journal of Biological Chemistry. 288: 10144-53. PMID 23426370 DOI: 10.1074/jbc.M113.451526  0.44
2012 Lowther J, Naismith JH, Dunn TM, Campopiano DJ. Structural, mechanistic and regulatory studies of serine palmitoyltransferase. Biochemical Society Transactions. 40: 547-54. PMID 22616865 DOI: 10.1042/BST20110769  0.44
2012 Wang E, Gao J, Yang Q, Parsley MO, Dunn TJ, Zhang L, DeWitt DS, Denner L, Prough DS, Wu P. Molecular mechanisms underlying effects of neural stem cells against traumatic axonal injury. Journal of Neurotrauma. 29: 295-312. PMID 22077363 DOI: 10.1089/neu.2011.2043  0.44
2011 Ojeda L, Gao J, Hooten KG, Wang E, Thonhoff JR, Dunn TJ, Gao T, Wu P. Critical role of PI3K/Akt/GSK3β in motoneuron specification from human neural stem cells in response to FGF2 and EGF. Plos One. 6: e23414. PMID 21887250 DOI: 10.1371/journal.pone.0023414  0.44
2011 Fortin DL, Dunn TW, Kramer RH. Engineering light-regulated ion channels. Cold Spring Harbor Protocols. 2011: 579-85. PMID 21632787 DOI: 10.1101/pdb.top112  0.8
2011 Fortin DL, Dunn TW, Fedorchak A, Allen D, Montpetit R, Banghart MR, Trauner D, Adelman JP, Kramer RH. Optogenetic photochemical control of designer K+ channels in mammalian neurons. Journal of Neurophysiology. 106: 488-96. PMID 21525363 DOI: 10.1152/jn.00251.2011  0.8
2011 Chao DY, Gable K, Chen M, Baxter I, Dietrich CR, Cahoon EB, Guerinot ML, Lahner B, Lü S, Markham JE, Morrissey J, Han G, Gupta SD, Harmon JM, Jaworski JG, ... Dunn TM, et al. Sphingolipids in the root play an important role in regulating the leaf ionome in Arabidopsis thaliana. The Plant Cell. 23: 1061-81. PMID 21421810 DOI: 10.1105/tpc.110.079095  0.44
2008 Fortin DL, Banghart MR, Dunn TW, Borges K, Wagenaar DA, Gaudry Q, Karakossian MH, Otis TS, Kristan WB, Trauner D, Kramer RH. Photochemical control of endogenous ion channels and cellular excitability. Nature Methods. 5: 331-8. PMID 18311146 DOI: 10.1038/nmeth.1187  0.8
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