| Year |
Citation |
Score |
| 2017 |
Hasbi A, Perreault ML, Shen MYF, Fan T, Nguyen T, Alijaniaram M, Banasikowski TJ, Grace AA, O'Dowd BF, Fletcher PJ, George SR. Activation of Dopamine D1-D2 Receptor Complex Attenuates Cocaine Reward and Reinstatement of Cocaine-Seeking through Inhibition of DARPP-32, ERK, and ΔFosB. Frontiers in Pharmacology. 8: 924. PMID 29354053 DOI: 10.3389/Fphar.2017.00924 |
0.575 |
|
| 2014 |
Hasbi A, Perreault ML, Shen MY, Zhang L, To R, Fan T, Nguyen T, Ji X, O'Dowd BF, George SR. A peptide targeting an interaction interface disrupts the dopamine D1-D2 receptor heteromer to block signaling and function in vitro and in vivo: effective selective antagonism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4806-20. PMID 25063849 DOI: 10.1096/Fj.14-254037 |
0.681 |
|
| 2014 |
Kabli N, Fan T, O'Dowd BF, George SR. μ-δ opioid receptor heteromer-specific signaling in the striatum and hippocampus. Biochemical and Biophysical Research Communications. 450: 906-11. PMID 24976397 DOI: 10.1016/J.Bbrc.2014.06.099 |
0.821 |
|
| 2014 |
Perreault ML, O'Dowd BF, George SR. Dopamine Dâ‚-Dâ‚‚ receptor heteromer regulates signaling cascades involved in addiction: potential relevance to adolescent drug susceptibility. Developmental Neuroscience. 36: 287-96. PMID 24820626 DOI: 10.1159/000360158 |
0.604 |
|
| 2014 |
Perreault ML, Hasbi A, O'Dowd BF, George SR. Heteromeric dopamine receptor signaling complexes: emerging neurobiology and disease relevance. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 156-68. PMID 23774533 DOI: 10.1038/Npp.2013.148 |
0.67 |
|
| 2013 |
Perreault ML, Fan T, O'Dowd BF, George SR. Enhanced brain-derived neurotrophic factor signaling in the nucleus accumbens of juvenile rats. Developmental Neuroscience. 35: 384-95. PMID 24021607 DOI: 10.1159/000351026 |
0.637 |
|
| 2013 |
O'Dowd BF, Nguyen T, Ji X, George SR. D5 dopamine receptor carboxyl tail involved in D5-D2 heteromer formation. Biochemical and Biophysical Research Communications. 431: 586-9. PMID 23318175 DOI: 10.1016/J.Bbrc.2012.12.139 |
0.661 |
|
| 2013 |
Novak G, Fan T, O'Dowd BF, George SR. Postnatal maternal deprivation and pubertal stress have additive effects on dopamine D2 receptor and CaMKII beta expression in the striatum. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 31: 189-95. PMID 23313435 DOI: 10.1016/J.Ijdevneu.2013.01.001 |
0.526 |
|
| 2013 |
Novak G, Fan T, O'Dowd BF, George SR. Striatal development involves a switch in gene expression networks, followed by a myelination event: implications for neuropsychiatric disease. Synapse (New York, N.Y.). 67: 179-88. PMID 23184870 DOI: 10.1002/Syn.21628 |
0.52 |
|
| 2013 |
Perreault ML, Jones-Tabah J, O'Dowd BF, George SR. A physiological role for the dopamine D5 receptor as a regulator of BDNF and Akt signalling in rodent prefrontal cortex. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 477-83. PMID 22827965 DOI: 10.1017/S1461145712000685 |
0.665 |
|
| 2013 |
Novak G, Fan T, O'Dowd BF, George SR. Striatal neurodevelopment involves a switch in gene expression and a myelination event F1000research. 4. DOI: 10.7490/F1000Research.1092847.1 |
0.506 |
|
| 2012 |
O'Dowd BF, Ji X, O'Dowd PB, Nguyen T, George SR. Disruption of the mu-delta opioid receptor heteromer. Biochemical and Biophysical Research Communications. 422: 556-60. PMID 22583900 DOI: 10.1016/J.Bbrc.2012.05.023 |
0.632 |
|
| 2012 |
Perreault ML, Fan T, Alijaniaram M, O'Dowd BF, George SR. Dopamine D1-D2 receptor heteromer in dual phenotype GABA/glutamate-coexpressing striatal medium spiny neurons: regulation of BDNF, GAD67 and VGLUT1/2. Plos One. 7: e33348. PMID 22428025 DOI: 10.1371/Journal.Pone.0033348 |
0.645 |
|
| 2012 |
O'Dowd BF, Ji X, Nguyen T, George SR. Two amino acids in each of D1 and D2 dopamine receptor cytoplasmic regions are involved in D1-D2 heteromer formation. Biochemical and Biophysical Research Communications. 417: 23-8. PMID 22100647 DOI: 10.1016/J.Bbrc.2011.11.027 |
0.643 |
|
| 2011 |
Perreault ML, Hasbi A, O'Dowd BF, George SR. The dopamine d1-d2 receptor heteromer in striatal medium spiny neurons: evidence for a third distinct neuronal pathway in Basal Ganglia. Frontiers in Neuroanatomy. 5: 31. PMID 21747759 DOI: 10.3389/Fnana.2011.00031 |
0.63 |
|
| 2011 |
Hasbi A, O'Dowd BF, George SR. Dopamine D1-D2 receptor heteromer signaling pathway in the brain: emerging physiological relevance. Molecular Brain. 4: 26. PMID 21663703 DOI: 10.1186/1756-6606-4-26 |
0.703 |
|
| 2011 |
O'Dowd BF, Ji X, Alijaniaram M, Nguyen T, George SR. Separation and reformation of cell surface dopamine receptor oligomers visualized in cells. European Journal of Pharmacology. 658: 74-83. PMID 21371461 DOI: 10.1016/J.Ejphar.2011.02.030 |
0.723 |
|
| 2011 |
Kong MM, Verma V, O'Dowd BF, George SR. The role of palmitoylation in directing dopamine D1 receptor internalization through selective endocytic routes. Biochemical and Biophysical Research Communications. 405: 445-9. PMID 21241663 DOI: 10.1016/J.Bbrc.2011.01.050 |
0.681 |
|
| 2011 |
Perreault ML, O'Dowd BF, George SR. Dopamine receptor homooligomers and heterooligomers in schizophrenia. Cns Neuroscience & Therapeutics. 17: 52-7. PMID 21199449 DOI: 10.1111/J.1755-5949.2010.00228.X |
0.663 |
|
| 2010 |
Kabli N, Martin N, Fan T, Nguyen T, Hasbi A, Balboni G, O'Dowd BF, George SR. Agonists at the δ-opioid receptor modify the binding of µ-receptor agonists to the µ-δ receptor hetero-oligomer. British Journal of Pharmacology. 161: 1122-36. PMID 20977461 DOI: 10.1111/J.1476-5381.2010.00944.X |
0.836 |
|
| 2010 |
Perreault ML, Hasbi A, Alijaniaram M, Fan T, Varghese G, Fletcher PJ, Seeman P, O'Dowd BF, George SR. The dopamine D1-D2 receptor heteromer localizes in dynorphin/enkephalin neurons: increased high affinity state following amphetamine and in schizophrenia. The Journal of Biological Chemistry. 285: 36625-34. PMID 20864528 DOI: 10.1074/Jbc.M110.159954 |
0.662 |
|
| 2010 |
Verma V, Hasbi A, O'Dowd BF, George SR. Dopamine D1-D2 receptor Heteromer-mediated calcium release is desensitized by D1 receptor occupancy with or without signal activation: dual functional regulation by G protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 285: 35092-103. PMID 20807772 DOI: 10.1074/Jbc.M109.088625 |
0.701 |
|
| 2010 |
Lee DK, Ferguson SS, George SR, O'Dowd BF. The fate of the internalized apelin receptor is determined by different isoforms of apelin mediating differential interaction with beta-arrestin. Biochemical and Biophysical Research Communications. 395: 185-9. PMID 20353754 DOI: 10.1016/J.Bbrc.2010.03.151 |
0.63 |
|
| 2010 |
Hasbi A, O'Dowd BF, George SR. Heteromerization of dopamine D2 receptors with dopamine D1 or D5 receptors generates intracellular calcium signaling by different mechanisms. Current Opinion in Pharmacology. 10: 93-9. PMID 19897420 DOI: 10.1016/J.Coph.2009.09.011 |
0.623 |
|
| 2010 |
El-Ghundi MB, Fan T, Karasinska JM, Yeung J, Zhou M, O'Dowd BF, George SR. Restoration of amphetamine-induced locomotor sensitization in dopamine D1 receptor-deficient mice. Psychopharmacology. 207: 599-618. PMID 19830406 DOI: 10.1007/S00213-009-1690-5 |
0.623 |
|
| 2009 |
Hasbi A, Fan T, Alijaniaram M, Nguyen T, Perreault ML, O'Dowd BF, George SR. Calcium signaling cascade links dopamine D1-D2 receptor heteromer to striatal BDNF production and neuronal growth. Proceedings of the National Academy of Sciences of the United States of America. 106: 21377-82. PMID 19948956 DOI: 10.1073/Pnas.0903676106 |
0.597 |
|
| 2009 |
So CH, Verma V, Alijaniaram M, Cheng R, Rashid AJ, O'Dowd BF, George SR. Calcium signaling by dopamine D5 receptor and D5-D2 receptor hetero-oligomers occurs by a mechanism distinct from that for dopamine D1-D2 receptor hetero-oligomers. Molecular Pharmacology. 75: 843-54. PMID 19171671 DOI: 10.1124/Mol.108.051805 |
0.669 |
|
| 2008 |
Juhasz JR, Hasbi A, Rashid AJ, So CH, George SR, O'Dowd BF. Mu-opioid receptor heterooligomer formation with the dopamine D1 receptor as directly visualized in living cells. European Journal of Pharmacology. 581: 235-43. PMID 18237729 DOI: 10.1016/J.Ejphar.2007.11.060 |
0.724 |
|
| 2007 |
George SR, O'Dowd BF. A novel dopamine receptor signaling unit in brain: heterooligomers of D1 and D2 dopamine receptors. Thescientificworldjournal. 7: 58-63. PMID 17982577 DOI: 10.1100/tsw.2007.223 |
0.676 |
|
| 2007 |
Rashid AJ, O'Dowd BF, Verma V, George SR. Neuronal Gq/11-coupled dopamine receptors: an uncharted role for dopamine. Trends in Pharmacological Sciences. 28: 551-5. PMID 17950471 DOI: 10.1016/J.Tips.2007.10.001 |
0.577 |
|
| 2007 |
Hasbi A, Nguyen T, Fan T, Cheng R, Rashid A, Alijaniaram M, Rasenick MM, O'Dowd BF, George SR. Trafficking of preassembled opioid mu-delta heterooligomer-Gz signaling complexes to the plasma membrane: coregulation by agonists. Biochemistry. 46: 12997-3009. PMID 17941650 DOI: 10.1021/Bi701436W |
0.663 |
|
| 2007 |
Kong MM, Hasbi A, Mattocks M, Fan T, O'Dowd BF, George SR. Regulation of D1 dopamine receptor trafficking and signaling by caveolin-1. Molecular Pharmacology. 72: 1157-70. PMID 17699686 DOI: 10.1124/mol.107.034769 |
0.64 |
|
| 2007 |
So CH, Verma V, O'Dowd BF, George SR. Desensitization of the dopamine D1 and D2 receptor hetero-oligomer mediated calcium signal by agonist occupancy of either receptor. Molecular Pharmacology. 72: 450-62. PMID 17519357 DOI: 10.1124/Mol.107.034884 |
0.657 |
|
| 2007 |
El-Ghundi M, O'Dowd BF, George SR. Insights into the role of dopamine receptor systems in learning and memory. Reviews in the Neurosciences. 18: 37-66. PMID 17405450 DOI: 10.1515/Revneuro.2007.18.1.37 |
0.598 |
|
| 2007 |
O'Dowd BF, Alijaniaram M, Ji X, Nguyen T, Eglen RM, George SR. Using ligand-induced conformational change to screen for compounds targeting G-protein-coupled receptors. Journal of Biomolecular Screening. 12: 175-85. PMID 17289935 DOI: 10.1177/1087057106298287 |
0.597 |
|
| 2007 |
Rashid AJ, So CH, Kong MM, Furtak T, El-Ghundi M, Cheng R, O'Dowd BF, George SR. D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum. Proceedings of the National Academy of Sciences of the United States of America. 104: 654-9. PMID 17194762 DOI: 10.1073/Pnas.0604049104 |
0.702 |
|
| 2006 |
Kong MM, Fan T, Varghese G, O'dowd BF, George SR. Agonist-induced cell surface trafficking of an intracellularly sequestered D1 dopamine receptor homo-oligomer. Molecular Pharmacology. 70: 78-89. PMID 16597839 DOI: 10.1124/mol.105.021246 |
0.651 |
|
| 2006 |
Lee DK, George SR, O'Dowd BF. Unravelling the roles of the apelin system: prospective therapeutic applications in heart failure and obesity. Trends in Pharmacological Sciences. 27: 190-4. PMID 16530855 DOI: 10.1016/j.tips.2006.02.006 |
0.591 |
|
| 2005 |
Karasinska JM, George SR, Cheng R, O'Dowd BF. Deletion of dopamine D1 and D3 receptors differentially affects spontaneous behaviour and cocaine-induced locomotor activity, reward and CREB phosphorylation. The European Journal of Neuroscience. 22: 1741-50. PMID 16197514 DOI: 10.1111/j.1460-9568.2005.04353.x |
0.563 |
|
| 2005 |
Fan T, Varghese G, Nguyen T, Tse R, O'Dowd BF, George SR. A role for the distal carboxyl tails in generating the novel pharmacology and G protein activation profile of mu and delta opioid receptor hetero-oligomers. The Journal of Biological Chemistry. 280: 38478-88. PMID 16159882 DOI: 10.1074/Jbc.M505644200 |
0.718 |
|
| 2005 |
O'Dowd BF, Ji X, Alijaniaram M, Rajaram RD, Kong MM, Rashid A, Nguyen T, George SR. Dopamine receptor oligomerization visualized in living cells. The Journal of Biological Chemistry. 280: 37225-35. PMID 16115864 DOI: 10.1074/Jbc.M504562200 |
0.7 |
|
| 2005 |
Hasbi A, O'Dowd BF, George SR. A G protein-coupled receptor for estrogen: the end of the search? Molecular Interventions. 5: 158-61. PMID 15994455 DOI: 10.1124/mi.5.3.5 |
0.568 |
|
| 2005 |
So CH, Varghese G, Curley KJ, Kong MM, Alijaniaram M, Ji X, Nguyen T, O'dowd BF, George SR. D1 and D2 dopamine receptors form heterooligomers and cointernalize after selective activation of either receptor. Molecular Pharmacology. 68: 568-78. PMID 15923381 DOI: 10.1124/Mol.105.012229 |
0.663 |
|
| 2005 |
Seeman P, Weinshenker D, Quirion R, Srivastava LK, Bhardwaj SK, Grandy DK, Premont RT, Sotnikova TD, Boksa P, El-Ghundi M, O'dowd BF, George SR, Perreault ML, Männistö PT, Robinson S, et al. Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 3513-8. PMID 15716360 DOI: 10.1073/Pnas.0409766102 |
0.702 |
|
| 2005 |
Lee DK, Saldivia VR, Nguyen T, Cheng R, George SR, O'Dowd BF. Modification of the terminal residue of apelin-13 antagonizes its hypotensive action. Endocrinology. 146: 231-6. PMID 15486224 DOI: 10.1210/En.2004-0359 |
0.519 |
|
| 2004 |
Lee SP, So CH, Rashid AJ, Varghese G, Cheng R, Lança AJ, O'Dowd BF, George SR. Dopamine D1 and D2 receptor Co-activation generates a novel phospholipase C-mediated calcium signal. The Journal of Biological Chemistry. 279: 35671-8. PMID 15159403 DOI: 10.1074/Jbc.M401923200 |
0.7 |
|
| 2004 |
Rashid AJ, O'Dowd BF, George SR. Minireview: Diversity and complexity of signaling through peptidergic G protein-coupled receptors. Endocrinology. 145: 2645-52. PMID 15044354 DOI: 10.1210/En.2004-0052 |
0.632 |
|
| 2004 |
Lee DK, Lança AJ, Cheng R, Nguyen T, Ji XD, Gobeil F, Chemtob S, George SR, O'Dowd BF. Agonist-independent nuclear localization of the Apelin, angiotensin AT1, and bradykinin B2 receptors. The Journal of Biological Chemistry. 279: 7901-8. PMID 14645236 DOI: 10.1074/Jbc.M306377200 |
0.676 |
|
| 2003 |
Madras BK, Fahey MA, Miller GM, De La Garza R, Goulet M, Spealman RD, Meltzer PC, George SR, O'Dowd BF, Bonab AA, Livni E, Fischman AJ. Non-amine-based dopamine transporter (reuptake) inhibitors retain properties of amine-based progenitors. European Journal of Pharmacology. 479: 41-51. PMID 14612136 DOI: 10.1016/J.Ejphar.2003.08.055 |
0.518 |
|
| 2003 |
Lee DK, George SR, O'Dowd BF. Continued discovery of ligands for G protein-coupled receptors. Life Sciences. 74: 293-7. PMID 14607257 DOI: 10.1016/J.Lfs.2003.09.016 |
0.667 |
|
| 2003 |
Lee SP, O'Dowd BF, George SR. Homo- and hetero-oligomerization of G protein-coupled receptors. Life Sciences. 74: 173-80. PMID 14607244 DOI: 10.1016/J.Lfs.2003.09.028 |
0.693 |
|
| 2003 |
Vanti WB, Muglia P, Nguyen T, Cheng R, Kennedy JL, George SR, O'Dowd BF. Discovery of a null mutation in a human trace amine receptor gene. Genomics. 82: 531-6. PMID 14559210 DOI: 10.1016/S0888-7543(03)00173-3 |
0.618 |
|
| 2003 |
Thompson MD, Storm van's Gravesande K, Galczenski H, Burnham WM, Siminovitch KA, Zamel N, Slutsky A, Drazen JM, George SR, Evans JF, O'Dowd BF. A cysteinyl leukotriene 2 receptor variant is associated with atopy in the population of Tristan da Cunha. Pharmacogenetics. 13: 641-9. PMID 14515063 DOI: 10.1097/01.fpc.0000054127.14659.42 |
0.612 |
|
| 2003 |
Lee SP, O'Dowd BF, Rajaram RD, Nguyen T, George SR. D2 dopamine receptor homodimerization is mediated by multiple sites of interaction, including an intermolecular interaction involving transmembrane domain 4. Biochemistry. 42: 11023-31. PMID 12974638 DOI: 10.1021/Bi0345539 |
0.652 |
|
| 2003 |
George SR, Ng GY, Lee SP, Fan T, Varghese G, Wang C, Deber CM, Seeman P, O'Dowd BF. Blockade of G protein-coupled receptors and the dopamine transporter by a transmembrane domain peptide: novel strategy for functional inhibition of membrane proteins in vivo. The Journal of Pharmacology and Experimental Therapeutics. 307: 481-9. PMID 12970389 DOI: 10.1124/Jpet.103.053843 |
0.619 |
|
| 2003 |
Vanti WB, Nguyen T, Cheng R, Lynch KR, George SR, O'Dowd BF. Novel human G-protein-coupled receptors. Biochemical and Biophysical Research Communications. 305: 67-71. PMID 12732197 DOI: 10.1016/S0006-291X(03)00709-5 |
0.611 |
|
| 2003 |
Tanaka H, Yoshida T, Miyamoto N, Motoike T, Kurosu H, Shibata K, Yamanaka A, Williams SC, Richardson JA, Tsujino N, Garry MG, Lerner MR, King DS, O'Dowd BF, Sakurai T, et al. Characterization of a family of endogenous neuropeptide ligands for the G protein-coupled receptors GPR7 and GPR8. Proceedings of the National Academy of Sciences of the United States of America. 100: 6251-6. PMID 12719537 DOI: 10.1073/Pnas.0837789100 |
0.435 |
|
| 2003 |
Karasinska JM, George SR, O'Dowd BF. Family 1 G protein-coupled receptor function in the CNS. Insights from gene knockout mice. Brain Research. Brain Research Reviews. 41: 125-52. PMID 12663079 DOI: 10.1016/S0165-0173(02)00221-7 |
0.601 |
|
| 2003 |
El-Ghundi M, O'Dowd BF, Erclik M, George SR. Attenuation of sucrose reinforcement in dopamine D1 receptor deficient mice. The European Journal of Neuroscience. 17: 851-62. PMID 12603275 DOI: 10.1046/J.1460-9568.2003.02496.X |
0.552 |
|
| 2002 |
Croston GE, Olsson R, Currier EA, Burstein ES, Weiner D, Nash N, Severance D, Allenmark SG, Thunberg L, Ma JN, Mohell N, O'Dowd B, Brann MR, Hacksell U. Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954). Journal of Medicinal Chemistry. 45: 4950-3. PMID 12408704 DOI: 10.1021/Jm025551+ |
0.539 |
|
| 2002 |
George SR, O'Dowd BF, Lee SP. G-protein-coupled receptor oligomerization and its potential for drug discovery. Nature Reviews. Drug Discovery. 1: 808-20. PMID 12360258 DOI: 10.1038/Nrd913 |
0.586 |
|
| 2002 |
Lee DK, George SR, O'Dowd BF. Novel G-protein-coupled receptor genes expressed in the brain: continued discovery of important therapeutic targets. Expert Opinion On Therapeutic Targets. 6: 185-202. PMID 12223080 DOI: 10.1517/14728222.6.2.185 |
0.675 |
|
| 2002 |
Levac BA, O'Dowd BF, George SR. Oligomerization of opioid receptors: generation of novel signaling units. Current Opinion in Pharmacology. 2: 76-81. PMID 11786312 DOI: 10.1016/S1471-4892(02)00124-8 |
0.688 |
|
| 2002 |
Lamey M, Thompson M, Varghese G, Chi H, Sawzdargo M, George SR, O'Dowd BF. Distinct residues in the carboxyl tail mediate agonist-induced desensitization and internalization of the human dopamine D1 receptor. The Journal of Biological Chemistry. 277: 9415-21. PMID 11773080 DOI: 10.1074/Jbc.M111811200 |
0.703 |
|
| 2001 |
Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF. Discovery and mapping of ten novel G protein-coupled receptor genes. Gene. 275: 83-91. PMID 11574155 DOI: 10.1016/S0378-1119(01)00651-5 |
0.646 |
|
| 2001 |
Clements MK, McDonald TP, Wang R, Xie G, O'Dowd BF, George SR, Austin CP, Liu Q. FMRFamide-related neuropeptides are agonists of the orphan G-protein-coupled receptor GPR54. Biochemical and Biophysical Research Communications. 284: 1189-93. PMID 11414709 DOI: 10.1006/Bbrc.2001.5098 |
0.648 |
|
| 2001 |
Im DS, Heise CE, Nguyen T, O'Dowd BF, Lynch KR. Identification of a molecular target of psychosine and its role in globoid cell formation. The Journal of Cell Biology. 153: 429-34. PMID 11309421 DOI: 10.1083/Jcb.153.2.429 |
0.42 |
|
| 2001 |
Nguyen T, Shapiro DA, George SR, Setola V, Lee DK, Cheng R, Rauser L, Lee SP, Lynch KR, Roth BL, O'Dowd BF. Discovery of a novel member of the histamine receptor family. Molecular Pharmacology. 59: 427-33. PMID 11179435 DOI: 10.1124/Mol.59.3.427 |
0.653 |
|
| 2000 |
Thompson MD, Gonzalez N, Nguyen T, Comings DE, George SR, O'Dowd BF. Serotonin transporter gene polymorphisms in alcohol dependence. Alcohol (Fayetteville, N.Y.). 22: 61-7. PMID 11113619 DOI: 10.1016/S0741-8329(00)00105-1 |
0.467 |
|
| 2000 |
Lee SP, Xie Z, Varghese G, Nguyen T, O'Dowd BF, George SR. Oligomerization of dopamine and serotonin receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: S32-40. PMID 11008065 DOI: 10.1016/S0893-133X(00)00155-X |
0.708 |
|
| 2000 |
Vandenbergh DJ, Thompson MD, Cook EH, Bendahhou E, Nguyen T, Krasowski MD, Zarrabian D, Comings D, Sellers EM, Tyndale RF, George SR, O'Dowd BF, Uhl GR. Human dopamine transporter gene: coding region conservation among normal, Tourette's disorder, alcohol dependence and attention-deficit hyperactivity disorder populations. Molecular Psychiatry. 5: 283-92. PMID 10889531 DOI: 10.1038/Sj.Mp.4000701 |
0.549 |
|
| 2000 |
Karasinska JM, George SR, El-Ghundi M, Fletcher PJ, O'Dowd BF. Modification of dopamine D(1) receptor knockout phenotype in mice lacking both dopamine D(1) and D(3) receptors. European Journal of Pharmacology. 399: 171-81. PMID 10884517 DOI: 10.1016/S0014-2999(00)00347-2 |
0.677 |
|
| 2000 |
Lee SP, O'Dowd BF, Ng GY, Varghese G, Akil H, Mansour A, Nguyen T, George SR. Inhibition of cell surface expression by mutant receptors demonstrates that D2 dopamine receptors exist as oligomers in the cell. Molecular Pharmacology. 58: 120-8. PMID 10860933 DOI: 10.1124/Mol.58.1.120 |
0.696 |
|
| 2000 |
George SR, Fan T, Xie Z, Tse R, Tam V, Varghese G, O'Dowd BF. Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties. The Journal of Biological Chemistry. 275: 26128-35. PMID 10842167 DOI: 10.1074/Jbc.M000345200 |
0.708 |
|
| 2000 |
Deng HB, Yu Y, Pak Y, O'Dowd BF, George SR, Surratt CK, Uhl GR, Wang JB. Role for the C-terminus in agonist-induced mu opioid receptor phosphorylation and desensitization. Biochemistry. 39: 5492-9. PMID 10820022 DOI: 10.1021/Bi991938B |
0.681 |
|
| 2000 |
Im DS, Heise CE, Harding MA, George SR, O'Dowd BF, Theodorescu D, Lynch KR. Molecular cloning and characterization of a lysophosphatidic acid receptor, Edg-7, expressed in prostate. Molecular Pharmacology. 57: 753-9. PMID 10727522 DOI: 10.1124/Mol.57.4.753 |
0.626 |
|
| 2000 |
Lee DK, Cheng R, Nguyen T, Fan T, Kariyawasam AP, Liu Y, Osmond DH, George SR, O'Dowd BF. Characterization of apelin, the ligand for the APJ receptor. Journal of Neurochemistry. 74: 34-41. PMID 10617103 DOI: 10.1046/J.1471-4159.2000.0740034.X |
0.594 |
|
| 1999 |
Jin H, Xie Z, George SR, O'Dowd BF. Palmitoylation occurs at cysteine 347 and cysteine 351 of the dopamine D(1) receptor. European Journal of Pharmacology. 386: 305-12. PMID 10618483 DOI: 10.1016/S0014-2999(99)00727-X |
0.654 |
|
| 1999 |
El-Ghundi M, Fletcher PJ, Drago J, Sibley DR, O'Dowd BF, George SR. Spatial learning deficit in dopamine D(1) receptor knockout mice. European Journal of Pharmacology. 383: 95-106. PMID 10585522 DOI: 10.1016/S0014-2999(99)00573-7 |
0.695 |
|
| 1999 |
Xie Z, Lee SP, O'Dowd BF, George SR. Serotonin 5-HT(1B) and 5-HT(1D) receptors form homodimers when expressed alone and heterodimers when co-expressed Febs Letters. 456: 63-67. PMID 10452531 DOI: 10.1016/S0014-5793(99)00918-7 |
0.667 |
|
| 1999 |
Lee DK, Nguyen T, Porter CA, Cheng R, George SR, O'Dowd BF. Two related G protein-coupled receptors: the distribution of GPR7 in rat brain and the absence of GPR8 in rodents. Brain Research. Molecular Brain Research. 71: 96-103. PMID 10407191 DOI: 10.1016/S0169-328X(99)00171-0 |
0.637 |
|
| 1999 |
Lee DK, Nguyen T, O'Neill GP, Cheng R, Liu Y, Howard AD, Coulombe N, Tan CP, Tang-Nguyen AT, George SR, O'Dowd BF. Discovery of a receptor related to the galanin receptors. Febs Letters. 446: 103-7. PMID 10100623 DOI: 10.1016/S0014-5793(99)00009-5 |
0.673 |
|
| 1999 |
Marchese A, Sawzdargo M, Nguyen T, Cheng R, Heng HH, Nowak T, Im DS, Lynch KR, George SR, O'dowd BF. Discovery of three novel orphan G-protein-coupled receptors. Genomics. 56: 12-21. PMID 10036181 DOI: 10.1006/Geno.1998.5655 |
0.678 |
|
| 1999 |
Sawzdargo M, Nguyen T, Lee DK, Lynch KR, Cheng R, Heng HH, George SR, O'Dowd BF. Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain. Brain Research. Molecular Brain Research. 64: 193-8. PMID 9931487 DOI: 10.1016/S0169-328X(98)00277-0 |
0.664 |
|
| 1998 |
Zawarynski P, Tallerico T, Seeman P, Lee SP, O'Dowd BF, George SR. Dopamine D2 receptor dimers in human and rat brain Febs Letters. 441: 383-386. PMID 9891976 DOI: 10.1016/S0014-5793(98)01588-9 |
0.685 |
|
| 1998 |
Kolakowski LF, O'Neill GP, Howard AD, Broussard SR, Sullivan KA, Feighner SD, Sawzdargo M, Nguyen T, Kargman S, Shiao LL, Hreniuk DL, Tan CP, Evans J, Abramovitz M, Chateauneuf A, et al. Molecular characterization and expression of cloned human galanin receptors GALR2 and GALR3. Journal of Neurochemistry. 71: 2239-51. PMID 9832121 DOI: 10.1046/J.1471-4159.1998.71062239.X |
0.589 |
|
| 1998 |
Edinger AL, Hoffman TL, Sharron M, Lee B, O'Dowd B, Doms RW. Use of GPR1, GPR15, and STRL33 as coreceptors by diverse human immunodeficiency virus type 1 and simian immunodeficiency virus envelope proteins. Virology. 249: 367-78. PMID 9791028 DOI: 10.1006/Viro.1998.9306 |
0.365 |
|
| 1998 |
El-Ghundi M, George SR, Drago J, Fletcher PJ, Fan T, Nguyen T, Liu C, Sibley DR, Westphal H, O'Dowd BF. Disruption of dopamine D1 receptor gene expression attenuates alcohol-seeking behavior. European Journal of Pharmacology. 353: 149-58. PMID 9726645 DOI: 10.1016/S0014-2999(98)00414-2 |
0.699 |
|
| 1998 |
Marchese A, Nguyen T, Malik P, Xu S, Cheng R, Xie Z, Heng HH, George SR, Kolakowski LF, O'Dowd BF. Cloning genes encoding receptors related to chemoattractant receptors. Genomics. 50: 281-6. PMID 9653656 DOI: 10.1006/Geno.1998.5297 |
0.66 |
|
| 1998 |
Thompson M, Comings DE, Feder L, George SR, O'Dowd BF. Mutation screening of the dopamine D1 receptor gene in Tourette's syndrome and alcohol dependent patients American Journal of Medical Genetics - Neuropsychiatric Genetics. 81: 241-244. PMID 9603612 DOI: 10.1002/(Sici)1096-8628(19980508)81:3<241::Aid-Ajmg7>3.0.Co;2-Z |
0.54 |
|
| 1998 |
Jin H, Nip S, O'Dowd BF, George SR. D1 dopamine receptor activity is not altered by a mutation in the first intracellular loop Biochimica Et Biophysica Acta - Molecular Cell Research. 1402: 165-170. PMID 9561802 DOI: 10.1016/S0167-4889(97)00159-6 |
0.717 |
|
| 1998 |
O'Dowd BF, Nguyen T, Marchese A, Cheng R, Lynch KR, Heng HH, Kolakowski LF, George SR. Discovery of three novel G-protein-coupled receptor genes. Genomics. 47: 310-3. PMID 9479505 DOI: 10.1006/Geno.1998.5095 |
0.653 |
|
| 1997 |
Sawzdargo M, George SR, Nguyen T, Xu S, Kolakowski LF, O'dowd BF. A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1 Biochemical and Biophysical Research Communications. 239: 543-547. PMID 9344866 DOI: 10.1006/Bbrc.1997.7513 |
0.577 |
|
| 1997 |
Jin H, Zastawny R, George SR, O'Dowd BF. Elimination of palmitoylation sites in the human dopamine D1 receptor does not affect receptor-G protein interaction European Journal of Pharmacology. 324: 109-116. PMID 9137920 DOI: 10.1016/S0014-2999(97)00059-9 |
0.741 |
|
| 1997 |
O'Dowd BF, Nguyen T, Jung BP, Marchese A, Cheng R, Heng HH, Kolakowski LF, Lynch KR, George SR. Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes. Gene. 187: 75-81. PMID 9073069 DOI: 10.1016/S0378-1119(96)00722-6 |
0.622 |
|
| 1997 |
Jung BP, Nguyen T, Kolakowski LF, Lynch KR, Heng HHQ, George SR, O'Dowd BF. Discovery of a novel human G protein-coupled receptor gene (GPR25) located on chromosome 1 Biochemical and Biophysical Research Communications. 230: 69-72. PMID 9020062 DOI: 10.1006/Bbrc.1996.5828 |
0.698 |
|
| 1996 |
Kolakowski LF, Jung BP, Nguyen T, Johnson MP, Lynch KR, Cheng R, Heng HHQ, George SR, O'Dowd BF. Characterization of a human gene related to genes encoding somatostatin receptors Febs Letters. 398: 253-258. PMID 8977118 DOI: 10.1016/S0014-5793(96)01160-X |
0.653 |
|
| 1996 |
Ng GYK, O'Dowd BF, George SR. Genotypic differences in mesolimbic enkephalin gene expression DBA/2J and C57BL/6J inbred mice European Journal of Pharmacology. 311: 45-52. PMID 8884235 DOI: 10.1016/0014-2999(96)00401-3 |
0.546 |
|
| 1996 |
Ng GYK, O'Dowd BF, Lee SP, Chung HT, Brann MR, Seeman P, George SR. Dopamine D2 receptor dimers and receptor-blocking peptides Biochemical and Biophysical Research Communications. 227: 200-204. PMID 8858125 DOI: 10.1006/Bbrc.1996.1489 |
0.72 |
|
| 1996 |
Heiber M, Marchese A, Nguyen T, Heng HH, George SR, O'Dowd BF. A novel human gene encoding a G-protein-coupled receptor (GPR15) is located on chromosome 3. Genomics. 32: 462-5. PMID 8838812 DOI: 10.1006/Geno.1996.0143 |
0.717 |
|
| 1996 |
O'Dowd BF, Nguyen T, Lynch KR, Kolakowski LF, Thompson M, Cheng R, Marchese A, Ng G, Heng HH, George SR. A novel gene codes for a putative G protein-coupled receptor with an abundant expression in brain. Febs Letters. 394: 325-9. PMID 8830667 DOI: 10.1016/0014-5793(96)00901-5 |
0.726 |
|
| 1996 |
Lam S, Shen Y, Nguyen T, Messier TL, Brann M, Comings D, George SR, O'Dowd BF. A serotonin receptor gene (5HT1A) variant found in a Tourette's Syndrome patient Biochemical and Biophysical Research Communications. 219: 853-858. PMID 8645269 DOI: 10.1006/Bbrc.1996.0322 |
0.662 |
|
| 1995 |
Nguyen T, Erb L, Weisman GA, Marchese A, Heng HH, Garrad RC, George SR, Turner JT, O'Dowd BF. Cloning, expression, and chromosomal localization of the human uridine nucleotide receptor gene. The Journal of Biological Chemistry. 270: 30845-8. PMID 8537335 DOI: 10.1074/Jbc.270.52.30845 |
0.698 |
|
| 1995 |
Marchese A, Beischlag TV, Nguyen T, Niznik HB, Weinshank RL, George SR, O'Dowd BF. Two gene duplication events in the human and primate dopamine D5 receptor gene family. Gene. 154: 153-8. PMID 7890157 DOI: 10.1016/0378-1119(94)00879-W |
0.656 |
|
| 1995 |
Bard JA, Nawoschik SP, O'Dowd BF, George SR, Branchek TA, Weinshank RL. The human serotonin 5-hydroxytryptamine1D receptor pseudogene is transcribed Gene. 153: 295-296. PMID 7875610 DOI: 10.1016/0378-1119(94)00693-M |
0.561 |
|
| 1995 |
O'Dowd BF, Scheideler MA, Nguyen T, Cheng R, Rasmussen JS, Marchese A, Zastawny R, Heng HH, Tsui LC, Shi X. The cloning and chromosomal mapping of two novel human opioid-somatostatin-like receptor genes, GPR7 and GPR8, expressed in discrete areas of the brain. Genomics. 28: 84-91. PMID 7590751 DOI: 10.1006/Geno.1995.1109 |
0.528 |
|
| 1995 |
Ng GY, Trogadis J, Stevens J, Bouvier M, O'Dowd BF, George SR. Agonist-induced desensitization of dopamine D1 receptor-stimulated adenylyl cyclase activity is temporally and biochemically separated from D1 receptor internalization. Proceedings of the National Academy of Sciences of the United States of America. 92: 10157-61. PMID 7479745 DOI: 10.1073/Pnas.92.22.10157 |
0.782 |
|
| 1994 |
Zastawny RL, George SR, Nguyen T, Cheng R, Tsatsos J, Briones-Urbina R, O'Dowd BF. Cloning, characterization, and distribution of a μ-opioid receptor in rat brain Journal of Neurochemistry. 62: 2099-2105. PMID 8189219 DOI: 10.1046/J.1471-4159.1994.62062099.X |
0.649 |
|
| 1994 |
Ren WZ, Ng GYK, Wang RX, Wu PH, O'Dowd BF, Osmond DH, George SR, Liew CC. The identification of NP25: a novel protein that is differentially expressed by neuronal subpopulations Molecular Brain Research. 22: 173-185. PMID 8015377 DOI: 10.1016/0169-328X(94)90045-0 |
0.511 |
|
| 1994 |
Ng GYK, O'Dowd BF, Caron M, Dennis M, Brann MR, George SR. Phosphorylation and palmitoylation of the human D2L dopamine receptor in Sf9 cells Journal of Neurochemistry. 63: 1589-1595. PMID 7931316 DOI: 10.1046/J.1471-4159.1994.63051589.X |
0.726 |
|
| 1994 |
Ng GY, O'Dowd BF, George SR. Genotypic differences in brain dopamine receptor function in the DBA/2J and C57BL/6J inbred mouse strains European Journal of Pharmacology: Molecular Pharmacology. 269: 349-364. PMID 7895774 DOI: 10.1016/0922-4106(94)90043-4 |
0.683 |
|
| 1994 |
Marchese A, Docherty JM, Nguyen T, Heiber M, Cheng R, Heng HH, Tsui LC, Shi X, George SR, O'Dowd BF. Cloning of human genes encoding novel G protein-coupled receptors. Genomics. 23: 609-18. PMID 7851889 DOI: 10.1006/Geno.1994.1549 |
0.673 |
|
| 1994 |
Laurier LG, O'Dowd BF, George SR. Heterogeneous tissue-specific transcription of dopamine receptor subtype messenger RNA in rat brain Molecular Brain Research. 25: 344-350. PMID 7808233 DOI: 10.1016/0169-328X(94)90170-8 |
0.685 |
|
| 1994 |
Ng GY, Mouillac B, George SR, Caron M, Dennis M, Bouvier M, O'Dowd BF. Desensitization, phosphorylation and palmitoylation of the human dopamine D1 receptor. European Journal of Pharmacology. 267: 7-19. PMID 7515822 DOI: 10.1016/0922-4106(94)90219-4 |
0.754 |
|
| 1993 |
Nguyen T, Marchese A, Kennedy JL, Petronis A, Peroutka SJ, Wu PH, O'Dowd BF. An Alu sequence interrupts a human 5-hydroxytryptamine1D receptor pseudogene. Gene. 124: 295-301. PMID 8444354 DOI: 10.1016/0378-1119(93)90409-V |
0.449 |
|
| 1993 |
O'Dowd BF. Structures of dopamine receptors Journal of Neurochemistry. 60: 804-816. PMID 8436971 DOI: 10.1111/J.1471-4159.1993.Tb03224.X |
0.512 |
|
| 1993 |
O'Dowd BF, Heiber M, Chan A, Heng HHQ, Tsui LC, Kennedy JL, Shi X, Petronis A, George SR, Nguyen T. A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11 Gene. 136: 355-360. PMID 8294032 DOI: 10.1016/0378-1119(93)90495-O |
0.666 |
|
| 1993 |
Ng GYK, George SR, Zastawny RL, Caron M, Bouvier M, Dennis M, O'Dowd BF. Human serotonin(1B) receptor expression in Sf9 cells: Phosphorylation, palmitoylation, and adenylyl cyclase inhibition Biochemistry. 32: 11727-11733. PMID 8218242 DOI: 10.1021/Bi00094A032 |
0.683 |
|
| 1993 |
Nöthen MM, Körner J, Lannfelt L, Sokoloff P, Schwartz Jc, Lanczik M, Rietschel M, Cichon S, Kramer R, Fimmers R, Möller Hj, Beckmann H, Propping P, Grandy DK, Civelli O, et al. Lack of association between schizophrenia and alleles of the dopamine D1, D2, D3 and D4 receptor loci1 Psychiatric Genetics. 3: 89-94. DOI: 10.1097/00041444-199322000-00004 |
0.523 |
|
| 1992 |
Maler T, Ralph MR, Gorczynski RM, Moldofsky H, O'Dowd BF, Du DC. The Drosophila per gene homologs are expressed in mammalian suprachiasmatic nucleus and heart as well as in molluscan eyes. Biochemical and Biophysical Research Communications. 184: 1082-7. PMID 1575727 DOI: 10.1016/0006-291X(92)90702-M |
0.338 |
|
| 1992 |
O'Dowd BF. Repeat sequences in the gene encoding the human D4 dopamine receptor Gene. 118: 301-302. PMID 1511906 DOI: 10.1016/0378-1119(92)90207-6 |
0.571 |
|
| 1992 |
Oksenberg D, Marsters SA, O'Dowd BF, Jin H, Havlik S, Peroutka SJ, Ashkenazi A. A single amino-acid difference confers major pharmacological variation between human and rodent 5-HT1B receptors. Nature. 360: 161-3. PMID 1436092 DOI: 10.1038/360161A0 |
0.583 |
|
| 1992 |
Mengod G, Villaró MT, Landwehrmeyer GB, Martinez-Mir MI, Niznik HB, Sunahara RK, Seeman P, O'Dowd BF, Probst A, Palacios JM. Visualization of dopamine D1, D2 and D3 receptor mRNAs in human and rat brain. Neurochemistry International. 20: 33S-43S. PMID 1365451 DOI: 10.1016/0197-0186(92)90208-9 |
0.493 |
|
| 1992 |
Lu Y, O'Dowd BF, Orrego H, Israel Y. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine γ-lyase Biochemical and Biophysical Research Communications. 189: 749-758. PMID 1339280 DOI: 10.1016/0006-291X(92)92265-Y |
0.302 |
|
| 1992 |
Palacios JM, Mengod G, Landwehrmeyer B, O'Dowd B, Probst A. Dopamine receptors: Molecular biology, pharmacology, neuroanatomy and alterations in movement disorders Movement Disorders. 7: 10-10. DOI: 10.1002/Mds.870070511 |
0.449 |
|
| 1991 |
Nguyen T, Sunahara R, Marchese A, Van Tol HH, Seeman P, O'Dowd BF. Transcription of a human dopamine D5 pseudogene. Biochemical and Biophysical Research Communications. 181: 16-21. PMID 1958184 DOI: 10.1016/S0006-291X(05)81375-0 |
0.371 |
|
| 1991 |
Sunahara RK, Guan HC, O'Dowd BF, Seeman P, Laurier LG, Ng G, George SR, Torchia J, Van Tol HHM, Niznik HB. Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1 Nature. 350: 614-619. PMID 1826762 DOI: 10.1038/350614A0 |
0.73 |
|
| 1991 |
Weiner DM, Levey AI, Sunahara RK, Niznik HB, O'Dowd BF, Seeman P, Brann MR. D1 and D2 dopamine receptor mRNA in rat brain. Proceedings of the National Academy of Sciences of the United States of America. 88: 1859-63. PMID 1825729 DOI: 10.1073/Pnas.88.5.1859 |
0.429 |
|
| 1991 |
Nguyen T, Bard J, Jin H, Taruscio D, Ward DC, Kennedy JL, Weinshank R, Seeman P, O'Dowd BF. Human dopamine D5 receptor pseudogenes Gene. 109: 211-218. PMID 1765268 DOI: 10.1016/0378-1119(91)90611-E |
0.497 |
|
| 1991 |
Collins S, Lohse MJ, O'Dowd B, Caron MG, Lefkowitz RJ. Structure and regulation of G protein-coupled receptors: the beta 2-adrenergic receptor as a model. Vitamins and Hormones. 46: 1-39. PMID 1660639 DOI: 10.1016/S0083-6729(08)60681-0 |
0.799 |
|
| 1991 |
Mengod G, Vilaró MT, Niznik HB, Sunahara RK, Seeman P, O'Dowd BF, Palacios JM. Visualization of a dopamine D1 receptor mRNA in human and rat brain. Brain Research. Molecular Brain Research. 10: 185-91. PMID 1649371 DOI: 10.1016/0169-328X(91)90110-J |
0.523 |
|
| 1990 |
O'Dowd BF, Nguyen T, Tirpak A, Jarvie KR, Israel Y, Seeman P, Niznik HB. Cloning of two additional catecholamine receptors from rat brain Febs Letters. 262: 8-12. PMID 2138567 DOI: 10.1016/0014-5793(90)80140-E |
0.538 |
|
| 1990 |
Seeman P, Niznik HB, Nguyen T, Tirpak A, Jarvie KR, Israel Y, O'Dowd BF. Neuroleptic/dopamine receptors: search for new g-linked receptors European Journal of Pharmacology. 183: 106-107. DOI: 10.1016/0014-2999(90)91368-L |
0.569 |
|
| 1989 |
Liggett SB, Bouvier M, O'Dowd BF, Caron MG, Lefkowitz RJ, DeBlasi A. Substitution of an extracellular cysteine in the beta 2-adrenergic receptor enhances agonist-promoted phosphorylation and receptor desensitization. Biochemical and Biophysical Research Communications. 165: 257-63. PMID 2556136 DOI: 10.1016/0006-291X(89)91063-2 |
0.798 |
|
| 1989 |
Palacios JM, O'Dowd BF, Cotecchia S, Hnatowich M, Caron MG, Lefkowitz RJ. Adrenergic receptor homologies in vertebrate and invertebrate species examined by DNA hybridization. Life Sciences. 44: 2057-65. PMID 2545987 DOI: 10.1016/0024-3205(89)90352-4 |
0.785 |
|
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