Frances Wiseman, MRes, PhD - Publications

2018- UCL Institute of Neurology, Queen Square, London, England, United Kingdom 
Ageing, Neuroscience, Down Syndrome, Alzheimer’s disease, Genetics

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ma D, Cardoso MJ, Zuluaga MA, Modat M, Powell NM, Wiseman FK, Cleary JO, Sinclair B, Harrison IF, Siow B, Popuri K, Lee S, Matsubara JA, Sarunic MV, Beg MF, et al. Substantially thinner internal granular layer and reduced molecular layer surface in the cerebellum of the Tc1 mouse model of Down Syndrome - a comprehensive morphometric analysis with active staining contrast-enhanced MRI. Neuroimage. 117271. PMID 32835824 DOI: 10.1016/j.neuroimage.2020.117271  0.36
2020 Cannavo C, Tosh J, Fisher EMC, Wiseman FK. Using mouse models to understand Alzheimer's disease mechanisms in the context of trisomy of chromosome 21. Progress in Brain Research. 251: 181-208. PMID 32057307 DOI: 10.1016/bs.pbr.2019.10.004  0.36
2020 Chang P, Bush D, Schorge S, Good M, Canonica T, Shing N, Noy S, Wiseman FK, Burgess N, Tybulewicz VLJ, Walker MC, Fisher EMC. Altered Hippocampal-Prefrontal Neural Dynamics in Mouse Models of Down Syndrome. Cell Reports. 30: 1152-1163.e4. PMID 31995755 DOI: 10.1016/j.celrep.2019.12.065  0.36
2019 Ahlfors H, Anyanwu N, Pakanavicius E, Dinischiotu N, Lana-Elola E, Watson-Scales S, Tosh J, Wiseman F, Briscoe J, Page K, Fisher EMC, Tybulewicz VLJ. Gene expression dysregulation domains are not a specific feature of Down syndrome. Nature Communications. 10: 2489. PMID 31171815 DOI: 10.1038/s41467-019-10129-9  0.36
2019 Granno S, Nixon-Abell J, Berwick DC, Tosh J, Heaton G, Almudimeegh S, Nagda Z, Rain JC, Zanda M, Plagnol V, Tybulewicz VLJ, Cleverley K, Wiseman FK, Fisher EMC, Harvey K. Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus. Scientific Reports. 9: 7322. PMID 31086297 DOI: 10.1038/s41598-019-43820-4  0.36
2018 Wiseman FK, Pulford LJ, Barkus C, Liao F, Portelius E, Webb R, Chávez-Gutiérrez L, Cleverley K, Noy S, Sheppard O, Collins T, Powell C, Sarell CJ, Rickman M, Choong X, et al. Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP. Brain : a Journal of Neurology. PMID 29945247 DOI: 10.1093/brain/awy159  0.44
2018 Watson-Scales S, Kalmar B, Lana-Elola E, Gibbins D, La Russa F, Wiseman F, Williamson M, Saccon R, Slender A, Olerinyova A, Mahmood R, Nye E, Cater H, Wells S, Yu YE, et al. Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration. Plos Genetics. 14: e1007383. PMID 29746474 DOI: 10.1371/journal.pgen.1007383  0.36
2016 Powell NM, Modat M, Cardoso MJ, Ma D, Holmes HE, Yu Y, O'Callaghan J, Cleary JO, Sinclair B, Wiseman FK, Tybulewicz VL, Fisher EM, Lythgoe MF, Ourselin S. Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome. Plos One. 11: e0162974. PMID 27658297 DOI: 10.1371/journal.pone.0162974  0.68
2016 Hall JH, Wiseman FK, Fisher EM, Tybulewicz VL, Harwood JL, Good MA. Tc1 mouse model of trisomy-21 dissociates properties of short- and long-term recognition memory. Neurobiology of Learning and Memory. PMID 26868479 DOI: 10.1016/j.nlm.2016.02.002  0.36
2015 Wiseman FK, Al-Janabi T, Hardy J, Karmiloff-Smith A, Nizetic D, Tybulewicz VL, Fisher EM, Strydom A. A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome. Nature Reviews. Neuroscience. 16: 564-74. PMID 26243569 DOI: 10.1038/nrn3983  0.36
2013 Gribble SM, Wiseman FK, Clayton S, Prigmore E, Langley E, Yang F, Maguire S, Fu B, Rajan D, Sheppard O, Scott C, Hauser H, Stephens PJ, Stebbings LA, Ng BL, et al. Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome. Plos One. 8: e60482. PMID 23596509 DOI: 10.1371/journal.pone.0060482  0.44
2013 Ahmed MM, Dhanasekaran AR, Tong S, Wiseman FK, Fisher EM, Tybulewicz VL, Gardiner KJ. Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brain. Human Molecular Genetics. 22: 1709-24. PMID 23349361 DOI: 10.1093/hmg/ddt017  0.68
2012 Grizenkova J, Akhtar S, Hummerich H, Tomlinson A, Asante EA, Wenborn A, Fizet J, Poulter M, Wiseman FK, Fisher EM, Tybulewicz VL, Brandner S, Collinge J, Lloyd SE. Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 13722-7. PMID 22869728 DOI: 10.1073/pnas.1208917109  0.36
2012 Sheppard O, Wiseman FK, Ruparelia A, Tybulewicz VL, Fisher EM. Mouse models of aneuploidy. Thescientificworldjournal. 2012: 214078. PMID 22262951 DOI: 10.1100/2012/214078  0.68
2012 Sheppard O, Plattner F, Rubin A, Slender A, Linehan JM, Brandner S, Tybulewicz VL, Fisher EM, Wiseman FK. Altered regulation of tau phosphorylation in a mouse model of down syndrome aging. Neurobiology of Aging. 33: 828.e31-44. PMID 21843906 DOI: 10.1016/j.neurobiolaging.2011.06.025  0.44
2011 Cleary JO, Wiseman FK, Norris FC, Price AN, Choy M, Tybulewicz VL, Ordidge RJ, Brandner S, Fisher EM, Lythgoe MF. Structural correlates of active-staining following magnetic resonance microscopy in the mouse brain. Neuroimage. 56: 974-83. PMID 21310249 DOI: 10.1016/j.neuroimage.2011.01.082  0.36
2010 Ruparelia A, Wiseman F, Sheppard O, Tybulewicz VL, Fisher EM. Down syndrome and the molecular pathogenesis resulting from trisomy of human chromosome 21. Journal of Biomedical Research. 24: 87-99. PMID 23554618 DOI: 10.1016/S1674-8301(10)60016-4  0.68
2010 Wiseman FK, Sheppard O, Linehan JM, Brandner S, Tybulewicz VL, Fisher EM. Generation of a panel of antibodies against proteins encoded on human chromosome 21. Journal of Negative Results in Biomedicine. 9: 7. PMID 20727138 DOI: 10.1186/1477-5751-9-7  0.68
2009 Wiseman FK, Alford KA, Tybulewicz VL, Fisher EM. Down syndrome--recent progress and future prospects. Human Molecular Genetics. 18: R75-83. PMID 19297404 DOI: 10.1093/hmg/ddp010  0.68
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