| Year |
Citation |
Score |
| 2023 |
Wu Y, Mumford P, Noy S, Cleverley K, Mrzyglod A, Luo D, van Dalen F, Verdoes M, Fisher EMC, Wiseman FK. Cathepsin B abundance, activity and microglial localisation in Alzheimer's disease-Down syndrome and early onset Alzheimer's disease; the role of elevated cystatin B. Acta Neuropathologica Communications. 11: 132. PMID 37580797 DOI: 10.1186/s40478-023-01632-8 |
0.329 |
|
| 2022 |
Mumford P, Tosh J, Anderle S, Wikberg EG, Lau G, Noy S, Cleverley K, Saito T, Saido TC, Yu E, Brinkmalm G, Portelius E, Blennow K, Zetterberg H, Tybulewicz V, ... ... Wiseman FK, et al. Genetic mapping of APP and amyloid-β biology modulation by trisomy 21. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35835549 DOI: 10.1523/JNEUROSCI.0521-22.2022 |
0.506 |
|
| 2022 |
Farrell C, Mumford P, Wiseman FK. Rodent Modeling of Alzheimer's Disease in Down Syndrome: and Approaches. Frontiers in Neuroscience. 16: 909669. PMID 35747206 DOI: 10.3389/fnins.2022.909669 |
0.667 |
|
| 2022 |
Cannavo C, Cleverley K, Maduro C, Mumford P, Moulding D, Fisher EMC, Wiseman FK. Endosomal structure and APP biology are not altered in a preclinical mouse cellular model of Down syndrome. Plos One. 17: e0262558. PMID 35544526 DOI: 10.1371/journal.pone.0262558 |
0.481 |
|
| 2022 |
Wu Y, West NR, Bhattacharyya A, Wiseman FK. Cell models for Down syndrome-Alzheimer's disease research. Neuronal Signaling. 6: NS20210054. PMID 35449591 DOI: 10.1042/NS20210054 |
0.453 |
|
| 2021 |
Wu Y, Whittaker HT, Noy S, Cleverley K, Brault V, Herault Y, Fisher EMC, Wiseman FK. The effects of Cstb duplication on APP/amyloid-β pathology and cathepsin B activity in a mouse model. Plos One. 16: e0242236. PMID 34292972 DOI: 10.1371/journal.pone.0242236 |
0.747 |
|
| 2021 |
Tosh JL, Rhymes ER, Mumford P, Whittaker HT, Pulford LJ, Noy SJ, Cleverley K, Walker MC, Tybulewicz VLJ, Wykes RC, Fisher EMC, Wiseman FK. Publisher Correction: Genetic dissection of down syndrome‑associated alterations in APP/amyloid‑β biology using mouse models. Scientific Reports. 11: 14966. PMID 34272456 DOI: 10.1038/s41598-021-94313-2 |
0.67 |
|
| 2021 |
Tosh JL, Rhymes ER, Mumford P, Whittaker HT, Pulford LJ, Noy SJ, Cleverley K, Walker MC, Tybulewicz VLJ, Wykes RC, Fisher EMC, Wiseman FK. Genetic dissection of down syndrome-associated alterations in APP/amyloid-β biology using mouse models. Scientific Reports. 11: 5736. PMID 33707583 DOI: 10.1038/s41598-021-85062-3 |
0.769 |
|
| 2020 |
Cannavo C, Tosh J, Fisher EMC, Wiseman FK. Using mouse models to understand Alzheimer's disease mechanisms in the context of trisomy of chromosome 21. Progress in Brain Research. 251: 181-208. PMID 32057307 DOI: 10.1016/Bs.Pbr.2019.10.004 |
0.369 |
|
| 2020 |
Wiseman FK. Understanding trisomy 21–associated alterations in APP/Amyloid‐β biology using mouse models Alzheimer's & Dementia. 16. DOI: 10.1002/alz.037466 |
0.321 |
|
| 2019 |
Ahlfors H, Anyanwu N, Pakanavicius E, Dinischiotu N, Lana-Elola E, Watson-Scales S, Tosh J, Wiseman F, Briscoe J, Page K, Fisher EMC, Tybulewicz VLJ. Gene expression dysregulation domains are not a specific feature of Down syndrome. Nature Communications. 10: 2489. PMID 31171815 DOI: 10.1038/S41467-019-10129-9 |
0.427 |
|
| 2019 |
Startin CM, Ashton NJ, Hamburg S, Hithersay R, Wiseman FK, Mok KY, Hardy J, Lleó A, Lovestone S, Parnetti L, Zetterberg H, Hye A, Strydom A. Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer's disease. Alzheimer's Research & Therapy. 11: 26. PMID 30902060 DOI: 10.1186/S13195-019-0477-0 |
0.394 |
|
| 2019 |
Wiseman FK, Pulford LJ, Barkus C, Liao F, Portelius E, Webb R, Chavez-Gutierrez L, Cleverley K, Noy S, Sheppard O, Collins T, Powell C, Sarell CJ, Rickman M, Choong X, et al. Trisomy of human chromosome 21 enhances amyloid-beta 3 deposition independently of an extra copy of APP (vol 141, pg 2457, 2018) Brain. 142. PMID 30879033 DOI: 10.1093/Brain/Awz061 |
0.73 |
|
| 2018 |
Wiseman FK, Pulford LJ, Barkus C, Liao F, Portelius E, Webb R, Chávez-Gutiérrez L, Cleverley K, Noy S, Sheppard O, Collins T, Powell C, Sarell CJ, Rickman M, Choong X, et al. Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP. Brain : a Journal of Neurology. PMID 29945247 DOI: 10.1093/Brain/Awy159 |
0.76 |
|
| 2018 |
Watson-Scales S, Kalmar B, Lana-Elola E, Gibbins D, La Russa F, Wiseman F, Williamson M, Saccon R, Slender A, Olerinyova A, Mahmood R, Nye E, Cater H, Wells S, Yu YE, et al. Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration. Plos Genetics. 14: e1007383. PMID 29746474 DOI: 10.1371/Journal.Pgen.1007383 |
0.403 |
|
| 2018 |
Whittaker HT, Zhu S, Di Curzio DL, Buist R, Li XM, Noy S, Wiseman FK, Thiessen JD, Martin M. T, diffusion tensor, and quantitative magnetization transfer imaging of the hippocampus in an Alzheimer's disease mouse model. Magnetic Resonance Imaging. PMID 29545212 DOI: 10.1016/J.Mri.2018.03.010 |
0.692 |
|
| 2017 |
Tosh JL, Rickman M, Rhymes E, Norona FE, Clayton E, Mucke L, Isaacs AM, Fisher EMC, Wiseman FK. The integration site of the APP transgene in the J20 mouse model of Alzheimer's disease. Wellcome Open Research. 2: 84. PMID 29062914 DOI: 10.12688/wellcomeopenres.12237.2 |
0.411 |
|
| 2017 |
Wiseman FK. TRISOMY 21 CAUSES A DEFICIT IN LYSOSOMAL CATHEPSINS AND ALTERS APP/Aβ PROCESSING INDEPENDENTLY OF AN EXTRA COPY OF APP Alzheimer's & Dementia. 13: P1212-P1213. DOI: 10.1016/j.jalz.2017.07.381 |
0.362 |
|
| 2017 |
Wiseman FK, Pulford LJ, Barkus C, Liao F, Portelius E, Webb R, Chavez-Gutierrez L, Cleverley K, Noy S, Rickman M, Tosh J, Whittaker H, Stewart F, Szaruga M, Nizetic D, et al. TRISOMY 21 CAUSES A DEFICIT IN LYSOSOMAL CATHEPSINS AND ALTERS APP/Aβ PROCESSING, INDEPENDENTLY OF AN EXTRA COPY OF APP Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.791 |
0.727 |
|
| 2016 |
Delabar JM, Allinquant B, Bianchi D, Blumenthal T, Dekker A, Edgin J, O'Bryan J, Dierssen M, Potier MC, Wiseman F, Guedj F, Créau N, Reeves R, Gardiner K, Busciglio J. Changing Paradigms in Down Syndrome: The First International Conference of the Trisomy 21 Research Society. Molecular Syndromology. 7: 251-261. PMID 27867340 DOI: 10.1159/000449049 |
0.448 |
|
| 2016 |
Powell NM, Modat M, Cardoso MJ, Ma D, Holmes HE, Yu Y, O'Callaghan J, Cleary JO, Sinclair B, Wiseman FK, Tybulewicz VL, Fisher EM, Lythgoe MF, Ourselin S. Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome. Plos One. 11: e0162974. PMID 27658297 DOI: 10.1371/Journal.Pone.0162974 |
0.549 |
|
| 2016 |
Hall JH, Wiseman FK, Fisher EM, Tybulewicz VL, Harwood JL, Good MA. Tc1 mouse model of trisomy-21 dissociates properties of short- and long-term recognition memory. Neurobiology of Learning and Memory. PMID 26868479 DOI: 10.1016/J.Nlm.2016.02.002 |
0.45 |
|
| 2016 |
Hall JH, Good MA, Fisher E, Wiseman FK, Harwood JL, Tybulewicz VL. P1-036: Dissociating Aberrant Memory Processes in Mouse Models of Alzheimer's Disease and Down Syndrome Alzheimer's & Dementia. 12: P414-P415. DOI: 10.1016/J.Jalz.2016.06.783 |
0.527 |
|
| 2015 |
Wiseman FK, Al-Janabi T, Hardy J, Karmiloff-Smith A, Nizetic D, Tybulewicz VL, Fisher EM, Strydom A. A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome. Nature Reviews. Neuroscience. 16: 564-74. PMID 26243569 DOI: 10.1038/Nrn3983 |
0.609 |
|
| 2014 |
Ma D, Cardoso MJ, Modat M, Powell N, Wells J, Holmes H, Wiseman F, Tybulewicz V, Fisher E, Lythgoe MF, Ourselin S. Automatic structural parcellation of mouse brain MRI using multi-atlas label fusion. Plos One. 9: e86576. PMID 24475148 DOI: 10.1371/Journal.Pone.0086576 |
0.487 |
|
| 2014 |
Holmes HE, Wiseman F, O'Callaghan JM, Wells J, Tybulewicz VL, Fisher EM, Lythgoe MF. P2-026: HYPOPERFUSION IN THE ABSENCE OF APP GENE TRIPLICATION IN THE TC1 MOUSE MODEL OF DOWN's SYNDROME Alzheimer's & Dementia. 10: P479-P480. DOI: 10.1016/J.Jalz.2014.05.699 |
0.582 |
|
| 2013 |
Gribble SM, Wiseman FK, Clayton S, Prigmore E, Langley E, Yang F, Maguire S, Fu B, Rajan D, Sheppard O, Scott C, Hauser H, Stephens PJ, Stebbings LA, Ng BL, et al. Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome. Plos One. 8: e60482. PMID 23596509 DOI: 10.1371/Journal.Pone.0060482 |
0.589 |
|
| 2013 |
Ahmed MM, Dhanasekaran AR, Tong S, Wiseman FK, Fisher EM, Tybulewicz VL, Gardiner KJ. Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brain. Human Molecular Genetics. 22: 1709-24. PMID 23349361 DOI: 10.1093/Hmg/Ddt017 |
0.527 |
|
| 2013 |
Choong XY, Raha A, Tybulewicz V, Wiseman F, Fisher E. P1-106: Using primary neurons from transgenic mice to identify genes on human chromosome 21 influencing Alzheimer's neuropathology Alzheimer's & Dementia. 9: P189-P189. DOI: 10.1016/J.Jalz.2013.05.328 |
0.619 |
|
| 2012 |
Grizenkova J, Akhtar S, Hummerich H, Tomlinson A, Asante EA, Wenborn A, Fizet J, Poulter M, Wiseman FK, Fisher EM, Tybulewicz VL, Brandner S, Collinge J, Lloyd SE. Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 13722-7. PMID 22869728 DOI: 10.1073/Pnas.1208917109 |
0.55 |
|
| 2012 |
Sheppard O, Wiseman FK, Ruparelia A, Tybulewicz VL, Fisher EM. Mouse models of aneuploidy. Thescientificworldjournal. 2012: 214078. PMID 22262951 DOI: 10.1100/2012/214078 |
0.582 |
|
| 2012 |
Sheppard O, Plattner F, Rubin A, Slender A, Linehan JM, Brandner S, Tybulewicz VL, Fisher EM, Wiseman FK. Altered regulation of tau phosphorylation in a mouse model of down syndrome aging. Neurobiology of Aging. 33: 828.e31-44. PMID 21843906 DOI: 10.1016/J.Neurobiolaging.2011.06.025 |
0.534 |
|
| 2011 |
Cleary JO, Wiseman FK, Norris FC, Price AN, Choy M, Tybulewicz VL, Ordidge RJ, Brandner S, Fisher EM, Lythgoe MF. Structural correlates of active-staining following magnetic resonance microscopy in the mouse brain. Neuroimage. 56: 974-83. PMID 21310249 DOI: 10.1016/J.Neuroimage.2011.01.082 |
0.473 |
|
| 2010 |
Ruparelia A, Wiseman F, Sheppard O, Tybulewicz VL, Fisher EM. Down syndrome and the molecular pathogenesis resulting from trisomy of human chromosome 21. Journal of Biomedical Research. 24: 87-99. PMID 23554618 DOI: 10.1016/S1674-8301(10)60016-4 |
0.602 |
|
| 2010 |
Wiseman FK, Sheppard O, Linehan JM, Brandner S, Tybulewicz VL, Fisher EM. Generation of a panel of antibodies against proteins encoded on human chromosome 21. Journal of Negative Results in Biomedicine. 9: 7. PMID 20727138 DOI: 10.1186/1477-5751-9-7 |
0.582 |
|
| 2009 |
Wiseman FK, Alford KA, Tybulewicz VL, Fisher EM. Down syndrome--recent progress and future prospects. Human Molecular Genetics. 18: R75-83. PMID 19297404 DOI: 10.1093/Hmg/Ddp010 |
0.559 |
|
| 2007 |
Cancellotti E, Barron RM, Bishop MT, Hart P, Wiseman F, Manson JC. The role of host PrP in Transmissible Spongiform Encephalopathies. Biochimica Et Biophysica Acta. 1772: 673-80. PMID 17150338 DOI: 10.1016/J.Bbadis.2006.10.013 |
0.305 |
|
| 2005 |
Cancellotti E, Wiseman F, Tuzi NL, Baybutt H, Monaghan P, Aitchison L, Simpson J, Manson JC. Altered glycosylated PrP proteins can have different neuronal trafficking in brain but do not acquire scrapie-like properties. The Journal of Biological Chemistry. 280: 42909-18. PMID 16219759 DOI: 10.1074/Jbc.M509557200 |
0.348 |
|
| 2005 |
Wiseman F, Cancellotti E, Manson J. Glycosylation and misfolding of PrP Biochemical Society Transactions. 33: 1094-1095. DOI: 10.1042/Bst0331094 |
0.335 |
|
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