| Year |
Citation |
Score |
| 2023 |
Maury EA, Sherman MA, Genovese G, Gilgenast TG, Kamath T, Burris SJ, Rajarajan P, Flaherty E, Akbarian S, Chess A, McCarroll SA, Loh PR, Phillips-Cremins JE, Brennand KJ, Macosko EZ, et al. Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent and disruptions. Cell Genomics. 3: 100356. PMID 37601975 DOI: 10.1016/j.xgen.2023.100356 |
0.78 |
|
| 2022 |
Farrelly LA, Zheng S, Schrode N, Topol A, Bhanu NV, Bastle RM, Ramakrishnan A, Chan JC, Cetin B, Flaherty E, Shen L, Gleason K, Tamminga CA, Garcia BA, Li H, et al. Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia. Nature Communications. 13: 2195. PMID 35459277 DOI: 10.1038/s41467-022-29922-0 |
0.796 |
|
| 2021 |
Lencz T, Yu J, Khan RR, Flaherty E, Carmi S, Lam M, Ben-Avraham D, Barzilai N, Bressman S, Darvasi A, Cho JH, Clark LN, Gümüş ZH, Vijai J, Klein RJ, et al. Novel ultra-rare exonic variants identified in a founder population implicate cadherins in schizophrenia. Neuron. PMID 33756103 DOI: 10.1016/j.neuron.2021.03.004 |
0.389 |
|
| 2020 |
Flaherty E, Maniatis T. The role of clustered protocadherins in neurodevelopment and neuropsychiatric diseases. Current Opinion in Genetics & Development. 65: 144-150. PMID 32679536 DOI: 10.1016/j.gde.2020.05.041 |
0.436 |
|
| 2020 |
Issler O, van der Zee YY, Ramakrishnan A, Wang J, Tan C, Loh YE, Purushothaman I, Walker DM, Lorsch ZS, Hamilton PJ, Peña CJ, Flaherty E, Hartley BJ, Torres-Berrío A, Parise EM, et al. Sex-Specific Role for the Long Non-coding RNA LINC00473 in Depression. Neuron. PMID 32304628 DOI: 10.1016/J.Neuron.2020.03.023 |
0.622 |
|
| 2020 |
Barretto N, Zhang H, Powell SK, Fernando MB, Zhang S, Flaherty EK, Ho SM, Slesinger PA, Duan J, Brennand KJ. ASCL1- and DLX2-induced GABAergic neurons from hiPSC-derived NPCs. Journal of Neuroscience Methods. 334: 108548. PMID 32065989 DOI: 10.1016/J.Jneumeth.2019.108548 |
0.771 |
|
| 2020 |
Farrelly L, Zhang S, Flaherty E, Topol A, Schrode N, Bastle R, Bhanu N, Garcia B, Li H, Brennand K, Maze I. T9. EPIGENETIC PROFILING IN SCHIZOPHRENIA DERIVED HUMAN INDUCED PLURIPOTENT STEM CELLS (HIPSCS) AND NEURONS Schizophrenia Bulletin. 46: S234-S234. DOI: 10.1093/Schbul/Sbaa029.569 |
0.74 |
|
| 2019 |
Flaherty E, Zhu S, Barretto N, Cheng E, Deans PJM, Fernando MB, Schrode N, Francoeur N, Antoine A, Alganem K, Halpern M, Deikus G, Shah H, Fitzgerald M, Ladran I, et al. Neuronal impact of patient-specific aberrant NRXN1α splicing. Nature Genetics. 51: 1679-1690. PMID 31784728 DOI: 10.1038/S41588-019-0539-Z |
0.764 |
|
| 2019 |
Schrode N, Ho SM, Yamamuro K, Dobbyn A, Huckins L, Matos MR, Cheng E, Deans PJM, Flaherty E, Barretto N, Topol A, Alganem K, Abadali S, Gregory J, Hoelzli E, et al. Synergistic effects of common schizophrenia risk variants. Nature Genetics. PMID 31548722 DOI: 10.1038/S41588-019-0497-5 |
0.786 |
|
| 2019 |
Rajarajan P, Flaherty E, Akbarian S, Brennand KJ. CRISPR-based functional evaluation of schizophrenia risk variants. Schizophrenia Research. PMID 31277978 DOI: 10.1016/J.Schres.2019.06.017 |
0.813 |
|
| 2019 |
Brennand K, Hoffman G, Schrode N, Flaherty E, Ho S. MODELING THE IMPACT OF RARE AND COMMON VARIANTS ON PREDISPOSITION TO SCHIZOPHRENIA USING STEM CELLS European Neuropsychopharmacology. 29: S1061. DOI: 10.1016/J.Euroneuro.2018.07.083 |
0.796 |
|
| 2019 |
Hoffman G, Hartley B, Flaherty E, Ladran I, Gochman P, Ruderfer D, Rapoport J, Sklar P, Brennand K. Transcriptional Signatures Of Childhood Onset Schizophrenia In Hipsc-Derived Npcs And Neurons Are Concordant With Signatures From Post Mortem Adult Brains European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.08.404 |
0.753 |
|
| 2018 |
Rajarajan P, Borrman T, Liao W, Schrode N, Flaherty E, Casiño C, Powell S, Yashaswini C, LaMarca EA, Kassim B, Javidfar B, Espeso-Gil S, Li A, Won H, Geschwind DH, et al. Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk. Science (New York, N.Y.). 362. PMID 30545851 DOI: 10.1126/Science.Aat4311 |
0.741 |
|
| 2018 |
Hoffman GE, Schrode N, Flaherty E, Brennand KJ. New considerations for hiPSC-based models of neuropsychiatric disorders. Molecular Psychiatry. PMID 29483625 DOI: 10.1038/S41380-018-0029-1 |
0.789 |
|
| 2017 |
Hoffman GE, Hartley BJ, Flaherty E, Ladran I, Gochman P, Ruderfer DM, Stahl EA, Rapoport J, Sklar P, Brennand KJ. Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains. Nature Communications. 8: 2225. PMID 29263384 DOI: 10.1038/S41467-017-02330-5 |
0.752 |
|
| 2017 |
Obiorah IV, Muhammad H, Stafford K, Flaherty EK, Brennand KJ. THC Treatment Alters Glutamate Receptor Gene Expression in Human Stem Cell-Derived Neurons. Molecular Neuropsychiatry. 3: 73-84. PMID 29230395 DOI: 10.1159/000477762 |
0.693 |
|
| 2017 |
Flaherty E, Deranieh RM, Artimovich E, Lee IS, Siegel AJ, Levy DL, Nestor MW, Brennand KJ. Patient-derived hiPSC neurons with heterozygous CNTNAP2 deletions display altered neuronal gene expression and network activity. Npj Schizophrenia. 3: 35. PMID 28975140 DOI: 10.1038/s41537-017-0033-5 |
0.722 |
|
| 2017 |
Flaherty E, Deranieh RM, Artimovich E, Lee IS, Siegel AJ, Levy DL, Nestor MW, Brennand KJ. Patient-derived hiPSC neurons with heterozygous CNTNAP2 deletions display altered neuronal gene expression and network activity. Npj Schizophrenia. 3: 35. PMID 28970473 DOI: 10.1038/s41537-017-0033-5 |
0.722 |
|
| 2017 |
Ho SM, Hartley BJ, Flaherty E, Rajarajan P, Abdelaal R, Obiorah I, Barretto N, Muhammad H, Phatnani HP, Akbarian S, Brennand KJ. Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes. Stem Cell Reports. PMID 28757163 DOI: 10.1016/J.Stemcr.2017.06.012 |
0.777 |
|
| 2015 |
Flaherty EK, Brennand KJ. Using hiPSCs to Model Neuropsychiatric Copy Number Variations (CNVs) has Potential to Reveal Underlying Disease Mechanisms. Brain Research. PMID 26581337 DOI: 10.1016/J.Brainres.2015.11.009 |
0.702 |
|
| 2015 |
Topol A, English JA, Flaherty E, Rajarajan P, Hartley BJ, Gupta S, Desland F, Zhu S, Goff T, Friedman L, Rapoport J, Felsenfeld D, Cagney G, Mackay-Sim A, Savas JN, et al. Increased abundance of translation machinery in stem cell-derived neural progenitor cells from four schizophrenia patients. Translational Psychiatry. 5: e662. PMID 26485546 DOI: 10.1038/Tp.2015.118 |
0.798 |
|
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