Jeffrey N. Savas - Publications

2015- Neurology Northwestern University, Evanston, IL 

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wang YZ, Perez-Rosello T, Smukowski SN, Surmeier DJ, Savas JN. Correction: Neuron type-specific proteomics reveals distinct Shank3 proteoforms in iSPNs and dSPNs lead to striatal synaptopathy in Shank3B mice. Molecular Psychiatry. PMID 38548985 DOI: 10.1038/s41380-024-02543-3  0.511
2024 Cardanho-Ramos C, Simões RA, Wang YZ, Faria-Pereira A, Bomba-Warczak E, Craessaerts K, Spinazzi M, Savas JN, Morais VA. Local mitochondrial replication in the periphery of neurons requires the eEF1A1 protein and thetranslation of nuclear-encoded proteins. Iscience. 27: 109136. PMID 38510136 DOI: 10.1016/j.isci.2024.109136  0.784
2024 Wang YZ, Perez-Rosello T, Smukowski SN, Surmeier DJ, Savas JN. Neuron type-specific proteomics reveals distinct Shank3 proteoforms in iPSNs and dSPNs lead to striatal synaptopathy in Shank3B mice. Molecular Psychiatry. PMID 38486049 DOI: 10.1038/s41380-024-02493-w  0.607
2024 Amici DR, Alhayek S, Klein AT, Wang YZ, Wilen AP, Song W, Zhu P, Thakkar A, King MA, Steffeck AW, Alasady MJ, Peek C, Savas JN, Mendillo ML. Tight regulation of a nuclear HAPSTR1-HUWE1 pathway essential for mammalian life. Life Science Alliance. 7. PMID 38453366 DOI: 10.26508/lsa.202302370  0.531
2024 Wang YZ, Castillon CCM, Gebis KK, Bartom ET, d'Azzo A, Contractor A, Savas JN. Notch receptor-ligand binding facilitates extracellular vesicle-mediated neuron-to-neuron communication. Cell Reports. 43: 113680. PMID 38241148 DOI: 10.1016/j.celrep.2024.113680  0.68
2024 Rao NR, Upadhyay A, Savas JN. Derailed protein turnover in the aging mammalian brain. Molecular Systems Biology. PMID 38182797 DOI: 10.1038/s44320-023-00009-2  0.641
2023 Bomba-Warczak EK, Velez KM, Zhou LT, Guillermier C, Edassery S, Steinhauser M, Savas JN, Duncan FE. Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan. Biorxiv : the Preprint Server For Biology. PMID 37905022 DOI: 10.1101/2023.10.18.562852  0.778
2023 Nomura T, Taniguchi S, Wang YZ, Yeh NH, Wilen AP, Castillon CCM, Foote KM, Xu J, Armstrong JN, Savas JN, Swanson GT, Contractor A. A pathogenic missense mutation in kainate receptors elevates dendritic excitability and synaptic integration through dysregulation of SK channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 37802657 DOI: 10.1523/JNEUROSCI.1259-23.2023  0.672
2023 Upadhyay A, Chhangani D, Rao NR, Kofler J, Vassar R, Rincon-Limas DE, Savas JN. Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity. Molecular Neurodegeneration. 18: 61. PMID 37710351 DOI: 10.1186/s13024-023-00654-z  0.701
2023 Savas JN. The cochlea is built to last a lifetime. Hearing Research. 436: 108821. PMID 37295280 DOI: 10.1016/j.heares.2023.108821  0.305
2023 Forrest MP, Dos Santos M, Piguel NH, Wang YZ, Hawkins NA, Bagchi VA, Dionisio LE, Yoon S, Simkin D, Martin-de-Saavedra MD, Gao R, Horan KE, George AL, LeDoux MS, Kearney JA, ... Savas JN, et al. Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub. Nature Communications. 14: 825. PMID 36808153 DOI: 10.1038/s41467-023-36087-x  0.473
2022 Fornasiero EF, Savas JN. Determining and interpreting protein lifetimes in mammalian tissues. Trends in Biochemical Sciences. PMID 36163144 DOI: 10.1016/j.tibs.2022.08.011  0.308
2022 Ramirez MA, Ninoyu Y, Miller C, Andrade LR, Edassery S, Bomba-Warczak E, Ortega B, Manor U, Rutherford MA, Friedman RA, Savas JN. Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3. Iscience. 25: 104803. PMID 35992071 DOI: 10.1016/j.isci.2022.104803  0.757
2022 Upadhyay A, Vassar RJ, Savas JN. Biochemical Purification and Proteomic Characterization of Amyloid Fibril Cores from the Brain. Journal of Visualized Experiments : Jove. PMID 35575522 DOI: 10.3791/63816  0.724
2022 Bomba-Warczak E, Savas JN. Long-lived mitochondrial proteins and why they exist. Trends in Cell Biology. PMID 35221146 DOI: 10.1016/j.tcb.2022.02.001  0.779
2021 Pegg CE, Zaichick SV, Bomba-Warczak E, Jovasevic V, Kim D, Kharkwal H, Wilson DW, Walsh D, Sollars PJ, Pickard GE, Savas JN, Smith GA. Herpesviruses assimilate kinesin to produce motorized viral particles. Nature. PMID 34789877 DOI: 10.1038/s41586-021-04106-w  0.74
2021 Bomba-Warczak E, Edassery SL, Hark TJ, Savas JN. Long-lived mitochondrial cristae proteins in mouse heart and brain. The Journal of Cell Biology. 220. PMID 34259807 DOI: 10.1083/jcb.202005193  0.78
2021 Bomba-Warczak E, Edassery SL, Hark TJ, Savas JN. Long-lived mitochondrial cristae proteins in mouse heart and brain. The Journal of Cell Biology. 220. PMID 34259807 DOI: 10.1083/jcb.202005193  0.78
2020 Hark TJ, Rao NR, Castillon C, Basta T, Smukowski S, Bao H, Upadhyay A, Bomba-Warczak E, Nomura T, O'Toole ET, Morgan GP, Ali L, Saito T, Guillermier C, Saido TC, ... ... Savas JN, et al. Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer's Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals. Cell Systems. PMID 33326751 DOI: 10.1016/j.cels.2020.11.007  0.766
2020 Graykowski DR, Wang YZ, Upadhyay A, Savas JN. The Dichotomous Role of Extracellular Vesicles in the Central Nervous System. Iscience. 23: 101456. PMID 32835924 DOI: 10.1016/J.Isci.2020.101456  0.713
2020 DiGiuseppe S, Rollins MG, Astar H, Khalatyan N, Savas JN, Walsh D. Proteomic and mechanistic dissection of the poxvirus-customized ribosome. Journal of Cell Science. PMID 32467327 DOI: 10.1242/Jcs.246603  0.363
2020 Ortega JA, Daley EL, Kour S, Samani M, Tellez L, Smith HS, Hall EA, Esengul YT, Tsai YH, Gendron TF, Donnelly CJ, Siddique T, Savas JN, Pandey UB, Kiskinis E. Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity. Neuron. PMID 32059759 DOI: 10.1016/J.Neuron.2020.01.020  0.399
2020 Piunti A, Smith E, Morgan M, Ugarenko M, Khaltyan N, Helmin K, Ryan C, Murray D, Rickels R, Yilmaz B, Rendleman E, Savas J, Singer B, Bulun S, Shilatifard A. Abstract B46: CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb Repressive complex 2 via a H3K27M-like mechanism Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-B46  0.345
2019 Liu P, Edassery SL, Ali L, Thomson BR, Savas JN, Jin J. Long-lived metabolic enzymes in the Crystallin lens identified by pulse-labeling of mice and mass spectrometry. Elife. 8. PMID 31820737 DOI: 10.7554/Elife.50170  0.364
2019 Zhao Z, Wang L, Bartom E, Marshall S, Rendleman E, Ryan C, Shilati A, Savas J, Chandel N, Shilatifard A. β-Catenin/Tcf7l2-dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer. Science Advances. 5: eaax0698. PMID 31392276 DOI: 10.1126/Sciadv.Aax0698  0.336
2019 Ruhl DA, Bomba-Warczak E, Watson ET, Bradberry MM, Peterson TA, Basu T, Frelka A, Evans CS, Briguglio JS, Basta T, Stowell MHB, Savas JN, Roopra A, Pearce RA, Piper RC, et al. Synaptotagmin 17 controls neurite outgrowth and synaptic physiology via distinct cellular pathways. Nature Communications. 10: 3532. PMID 31387992 DOI: 10.1038/S41467-019-11459-4  0.781
2019 Piunti A, Smith ER, Morgan MAJ, Ugarenko M, Khaltyan N, Helmin KA, Ryan CA, Murray DC, Rickels RA, Yilmaz BD, Rendleman EJ, Savas JN, Singer BD, Bulun SE, Shilatifard A. CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism. Science Advances. 5: eaax2887. PMID 31281901 DOI: 10.1126/Sciadv.Aax2887  0.304
2019 Kim JJ, Savas JN, Miller MT, Hu X, Carromeu C, Lavallée-Adam M, Freitas BCG, Muotri AR, Yates JR, Ghosh A. Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function. Plos One. 14: e0212553. PMID 30789962 DOI: 10.1371/Journal.Pone.0212553  0.354
2019 Rice HC, de Malmazet D, Schreurs A, Frere S, Van Molle I, Volkov AN, Creemers E, Vertkin I, Nys J, Ranaivoson FM, Comoletti D, Savas JN, Remaut H, Balschun D, Wierda KD, et al. Secreted amyloid-β precursor protein functions as a GABAR1a ligand to modulate synaptic transmission. Science (New York, N.Y.). 363. PMID 30630900 DOI: 10.1126/Science.Aao4827  0.416
2019 Forrest M, Wang Y, Piguel N, Simkin D, Hawkins N, Santos MD, Dionisio L, Bachi V, Kearney J, Savas J, Penzes P. T124. Proteomic Profiling of the 16p11.2 Microduplication Mouse Model: Implications for Neuropsychiatric Disease Biological Psychiatry. 85: S177. DOI: 10.1016/J.Biopsych.2019.03.447  0.514
2018 Condomitti G, Wierda KD, Schroeder A, Rubio SE, Vennekens KM, Orlandi C, Martemyanov KA, Gounko NV, Savas JN, de Wit J. An Input-Specific Orphan Receptor GPR158-HSPG Interaction Organizes Hippocampal Mossy Fiber-CA3 Synapses. Neuron. 100: 201-215.e9. PMID 30290982 DOI: 10.1016/J.Neuron.2018.08.038  0.326
2018 Liu P, Thomson BR, Khalatyan N, Feng L, Liu X, Savas JN, Quaggin SE, Jin J. Selective permeability of mouse blood-aqueous barrier as determined by N-heavy isotope tracing and mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. PMID 30127000 DOI: 10.1073/Pnas.1807982115  0.32
2018 Wang YZ, Savas JN. Uncovering Discrete Synaptic Proteomes to Understand Neurological Disorders. Proteomes. 6. PMID 30029459 DOI: 10.3390/Proteomes6030030  0.627
2018 He Q, Arroyo ED, Smukowski SN, Xu J, Piochon C, Savas JN, Portera-Cailliau C, Contractor A. Critical period inhibition of NKCC1 rectifies synapse plasticity in the somatosensory cortex and restores adult tactile response maps in fragile X mice. Molecular Psychiatry. PMID 29703945 DOI: 10.1038/S41380-018-0048-Y  0.594
2018 Penzes P, Savas J, Forrest M. 16. Synaptic Mechanisms in 16p11.2 Duplication Model Mice Biological Psychiatry. 83: S6-S7. DOI: 10.1016/J.Biopsych.2018.02.033  0.31
2017 Savas JN, Wang YZ, DeNardo LA, Martinez-Bartolome S, McClatchy DB, Hark TJ, Shanks NF, Cozzolino KA, Lavallée-Adam M, Smukowski SN, Park SK, Kelly JW, Koo EH, Nakagawa T, Masliah E, et al. Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology. Cell Reports. 21: 2614-2627. PMID 29186695 DOI: 10.1016/J.Celrep.2017.11.009  0.629
2017 Wang L, Collings CK, Zhao Z, Cozzolino KA, Ma Q, Liang K, Marshall SA, Sze CC, Hashizume R, Savas JN, Shilatifard A. A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism. Genes & Development. PMID 29138278 DOI: 10.1101/Gad.306092.117  0.337
2017 Elegheert J, Cvetkovska V, Clayton AJ, Heroven C, Vennekens KM, Smukowski SN, Regan MC, Jia W, Smith AC, Furukawa H, Savas JN, de Wit J, Begbie J, Craig AM, Aricescu AR. Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins. Neuron. 96: 242-244. PMID 28957672 DOI: 10.1016/J.Neuron.2017.09.011  0.383
2017 Burbulla LF, Song P, Mazzulli JR, Zampese E, Wong YC, Jeon S, Santos DP, Blanz J, Obermaier CD, Strojny C, Savas JN, Kiskinis E, Zhuang X, Krüger R, Surmeier DJ, et al. Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease. Science (New York, N.Y.). PMID 28882997 DOI: 10.1126/Science.Aam9080  0.305
2017 Elegheert J, Cvetkovska V, Clayton AJ, Heroven C, Vennekens KM, Smukowski SN, Regan MC, Jia W, Smith AC, Furukawa H, Savas JN, de Wit J, Begbie J, Craig AM, Aricescu AR. Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins. Neuron. 95: 896-913.e10. PMID 28817804 DOI: 10.1016/J.Neuron.2017.07.040  0.374
2017 Jha S, Rollins MG, Fuchs G, Procter DJ, Hall EA, Cozzolino K, Sarnow P, Savas JN, Walsh D. Trans-kingdom mimicry underlies ribosome customization by a poxvirus kinase. Nature. PMID 28636603 DOI: 10.1038/Nature22814  0.301
2017 Rice HC, Wierda KD, Frere S, Vertkin I, Van Molle I, Ranaivoson F, Comoletti D, Savas JN, Slutsky I, De Strooper B, de Wit J. SOLUBLE AMYLOID PRECURSOR PROTEIN IS AN ISOFORM-SPECIFIC GABA(B) RECEPTOR LIGAND THAT SUPPRESSES SYNAPTIC RELEASE PROBABILITY Alzheimer's & Dementia. 13: P206. DOI: 10.1016/J.Jalz.2017.07.075  0.344
2016 Hickox AE, Wong AC, Pak K, Strojny C, Ramirez M, Yates JR, Ryan AF, Savas JN. Global Analysis of Protein Expression of Inner Ear Hair Cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28039372 DOI: 10.1523/Jneurosci.2267-16.2016  0.793
2016 Schreiner D, Savas JN, Herzog E, Brose N, de Wit J. Synapse biology in the 'circuit-age'-paths toward molecular connectomics. Current Opinion in Neurobiology. 42: 102-110. PMID 28033531 DOI: 10.1016/J.Conb.2016.12.004  0.35
2016 Mita P, Savas JN, Briggs EM, Ha S, Gnanakkan V, Yates JR, Robins DM, David G, Boeke JD, Garabedian MJ, Logan SK. URI Regulates KAP1 Phosphorylation and Transcriptional Repression Via PP2A Phosphatase in Prostate Cancer Cells. The Journal of Biological Chemistry. PMID 27780869 DOI: 10.1074/Jbc.M116.741660  0.361
2016 Yonashiro R, Tahara EB, Bengtson MH, Khokhrina M, Lorenz H, Chen KC, Kigoshi-Tansho Y, Savas JN, Yates JR, Kay SA, Craig EA, Mogk A, Bukau B, Joazeiro CA. The Rqc2/Tae2 subunit of the ribosome-associated quality control (RQC) complex marks ribosome-stalled nascent polypeptide chains for aggregation. Elife. 5. PMID 26943317 DOI: 10.7554/Elife.11794  0.347
2016 Savas JN, Park SK, Yates JR. Proteomic Analysis of Protein Turnover by Metabolic Whole Rodent Pulse-Chase Isotopic Labeling and Shotgun Mass Spectrometry Analysis. Methods in Molecular Biology (Clifton, N.J.). 1410: 293-304. PMID 26867752 DOI: 10.1007/978-1-4939-3524-6_18  0.4
2015 Topol A, English JA, Flaherty E, Rajarajan P, Hartley BJ, Gupta S, Desland F, Zhu S, Goff T, Friedman L, Rapoport J, Felsenfeld D, Cagney G, Mackay-Sim A, Savas JN, et al. Increased abundance of translation machinery in stem cell-derived neural progenitor cells from four schizophrenia patients. Translational Psychiatry. 5: e662. PMID 26485546 DOI: 10.1038/Tp.2015.118  0.352
2015 Savas JN, Ribeiro LF, Wierda KD, Wright R, DeNardo-Wilke LA, Rice HC, Chamma I, Wang YZ, Zemla R, Lavallée-Adam M, Vennekens KM, O'Sullivan ML, Antonios JK, Hall EA, Thoumine O, et al. The Sorting Receptor SorCS1 Regulates Trafficking of Neurexin and AMPA Receptors. Neuron. 87: 764-80. PMID 26291160 DOI: 10.1016/J.Neuron.2015.08.007  0.589
2015 McClatchy DB, Savas JN, Martínez-Bartolomé S, Park SK, Maher P, Powell SB, Yates JR. Global quantitative analysis of phosphorylation underlying phencyclidine signaling and sensorimotor gating in the prefrontal cortex. Molecular Psychiatry. PMID 25869802 DOI: 10.1038/Mp.2015.41  0.311
2015 Brennand K, Savas JN, Kim Y, Tran N, Simone A, Hashimoto-Torii K, Beaumont KG, Kim HJ, Topol A, Ladran I, Abdelrahim M, Matikainen-Ankney B, Chao SH, Mrksich M, Rakic P, et al. Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia. Molecular Psychiatry. 20: 361-8. PMID 24686136 DOI: 10.1038/Mp.2014.22  0.335
2014 Savas JN, De Wit J, Comoletti D, Zemla R, Ghosh A, Yates JR. Ecto-Fc MS identifies ligand-receptor interactions through extracellular domain Fc fusion protein baits and shotgun proteomic analysis. Nature Protocols. 9: 2061-74. PMID 25101821 DOI: 10.1038/Nprot.2014.140  0.34
2014 Lee GH, Chhangawala Z, von Daake S, Savas JN, Yates JR, Comoletti D, D'Arcangelo G. Reelin induces Erk1/2 signaling in cortical neurons through a non-canonical pathway. The Journal of Biological Chemistry. 289: 20307-17. PMID 24876378 DOI: 10.1074/Jbc.M114.576249  0.384
2013 Parkhurst CN, Yang G, Ninan I, Savas JN, Yates JR, Lafaille JJ, Hempstead BL, Littman DR, Gan WB. Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor. Cell. 155: 1596-609. PMID 24360280 DOI: 10.1016/J.Cell.2013.11.030  0.34
2013 Wan J, Savas JN, Roth AF, Sanders SS, Singaraja RR, Hayden MR, Yates JR, Davis NG. Tracking brain palmitoylation change: predominance of glial change in a mouse model of Huntington's disease. Chemistry & Biology. 20: 1421-34. PMID 24211138 DOI: 10.1016/J.Chembiol.2013.09.018  0.367
2013 Toyama BH, Savas JN, Park SK, Harris MS, Ingolia NT, Yates JR, Hetzer MW. Identification of long-lived proteins reveals exceptional stability of essential cellular structures. Cell. 154: 971-82. PMID 23993091 DOI: 10.1016/J.Cell.2013.07.037  0.435
2013 de Wit J, O'Sullivan ML, Savas JN, Condomitti G, Caccese MC, Vennekens KM, Yates JR, Ghosh A. Unbiased discovery of glypican as a receptor for LRRTM4 in regulating excitatory synapse development. Neuron. 79: 696-711. PMID 23911103 DOI: 10.1016/J.Neuron.2013.06.049  0.398
2013 Mita P, Savas JN, Ha S, Djouder N, Yates JR, Logan SK. Analysis of URI nuclear interaction with RPB5 and components of the R2TP/prefoldin-like complex. Plos One. 8: e63879. PMID 23667685 DOI: 10.1371/Journal.Pone.0063879  0.363
2013 Butko MT, Savas JN, Friedman B, Delahunty C, Ebner F, Yates JR, Tsien RY. In vivo quantitative proteomics of somatosensory cortical synapses shows which protein levels are modulated by sensory deprivation. Proceedings of the National Academy of Sciences of the United States of America. 110: E726-35. PMID 23382246 DOI: 10.1073/Pnas.1300424110  0.442
2012 Shanks NF, Savas JN, Maruo T, Cais O, Hirao A, Oe S, Ghosh A, Noda Y, Greger IH, Yates JR, Nakagawa T. Differences in AMPA and kainate receptor interactomes facilitate identification of AMPA receptor auxiliary subunit GSG1L. Cell Reports. 1: 590-8. PMID 22813734 DOI: 10.1016/J.Celrep.2012.05.004  0.339
2012 Ma B, Savas JN, Chao MV, Tanese N. Quantitative analysis of BDNF/TrkB protein and mRNA in cortical and striatal neurons using α-tubulin as a normalization factor. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 704-17. PMID 22649026 DOI: 10.1002/Cyto.A.22073  0.696
2012 Culver BP, Savas JN, Park SK, Choi JH, Zheng S, Zeitlin SO, Yates JR, Tanese N. Proteomic analysis of wild-type and mutant huntingtin-associated proteins in mouse brains identifies unique interactions and involvement in protein synthesis. The Journal of Biological Chemistry. 287: 21599-614. PMID 22556411 DOI: 10.1074/Jbc.M112.359307  0.71
2012 O'Sullivan ML, de Wit J, Savas JN, Comoletti D, Otto-Hitt S, Yates JR, Ghosh A. FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development. Neuron. 73: 903-10. PMID 22405201 DOI: 10.1016/J.Neuron.2012.01.018  0.403
2012 Savas JN, Toyama BH, Xu T, Yates JR, Hetzer MW. Extremely long-lived nuclear pore proteins in the rat brain. Science (New York, N.Y.). 335: 942. PMID 22300851 DOI: 10.1126/Science.1217421  0.406
2012 Jeong H, Cohen DE, Cui L, Supinski A, Savas JN, Mazzulli JR, Yates JR, Bordone L, Guarente L, Krainc D. Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway. Nature Medicine. 18: 159-65. PMID 22179316 DOI: 10.1038/Nm.2559  0.379
2011 Ma B, Savas JN, Yu MS, Culver BP, Chao MV, Tanese N. Huntingtin mediates dendritic transport of β-actin mRNA in rat neurons. Scientific Reports. 1: 140. PMID 22355657 DOI: 10.1038/Srep00140  0.692
2011 Mita P, Savas JN, Djouder N, Yates JR, Ha S, Ruoff R, Schafler ED, Nwachukwu JC, Tanese N, Cowan NJ, Zavadil J, Garabedian MJ, Logan SK. Regulation of androgen receptor-mediated transcription by RPB5 binding protein URI/RMP. Molecular and Cellular Biology. 31: 3639-52. PMID 21730289 DOI: 10.1128/Mcb.05429-11  0.644
2011 Savas JN, Stein BD, Wu CC, Yates JR. Mass spectrometry accelerates membrane protein analysis. Trends in Biochemical Sciences. 36: 388-96. PMID 21616670 DOI: 10.1016/J.Tibs.2011.04.005  0.366
2010 Pham E, Crews L, Ubhi K, Hansen L, Adame A, Cartier A, Salmon D, Galasko D, Michael S, Savas JN, Yates JR, Glabe C, Masliah E. Progressive accumulation of amyloid-beta oligomers in Alzheimer's disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins. The Febs Journal. 277: 3051-67. PMID 20573181 DOI: 10.1111/J.1742-4658.2010.07719.X  0.432
2010 Savas JN, Ma B, Deinhardt K, Culver BP, Restituito S, Wu L, Belasco JG, Chao MV, Tanese N. A role for huntington disease protein in dendritic RNA granules. The Journal of Biological Chemistry. 285: 13142-53. PMID 20185826 DOI: 10.1074/Jbc.M110.114561  0.697
2010 Savas JN, Tanese N. A combined immunoprecipitation, mass spectrometric and nucleic acid sequencing approach to determine microRNA-mediated post-transcriptional gene regulatory networks. Briefings in Functional Genomics. 9: 24-31. PMID 20053813 DOI: 10.1093/Bfgp/Elp050  0.651
2009 de Wit J, Sylwestrak E, O'Sullivan ML, Otto S, Tiglio K, Savas JN, Yates JR, Comoletti D, Taylor P, Ghosh A. LRRTM2 interacts with Neurexin1 and regulates excitatory synapse formation. Neuron. 64: 799-806. PMID 20064388 DOI: 10.1016/J.Neuron.2009.12.019  0.388
2009 Jeong H, Then F, Melia TJ, Mazzulli JR, Cui L, Savas JN, Voisine C, Paganetti P, Tanese N, Hart AC, Yamamoto A, Krainc D. Acetylation targets mutant huntingtin to autophagosomes for degradation. Cell. 137: 60-72. PMID 19345187 DOI: 10.1016/J.Cell.2009.03.018  0.698
2008 Savas JN, Makusky A, Ottosen S, Baillat D, Then F, Krainc D, Shiekhattar R, Markey SP, Tanese N. Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies. Proceedings of the National Academy of Sciences of the United States of America. 105: 10820-5. PMID 18669659 DOI: 10.1073/Pnas.0800658105  0.739
2007 Williams E, Lowe TM, Savas J, DiRuggiero J. Microarray analysis of the hyperthermophilic archaeon Pyrococcus furiosus exposed to gamma irradiation. Extremophiles : Life Under Extreme Conditions. 11: 19-29. PMID 16896524 DOI: 10.1007/S00792-006-0002-9  0.306
2006 Savas JN, Hark TJ, Bomba-Warczak EK, Ali LF. P2-097: THE ROLE OF IMPAIRED PROTEIN DEGRADATION DYNAMICS AND PROTEOME REMODELING IN AMYLOID PROTEOTOXICITY Alzheimer's & Dementia. 14: P704-P705. DOI: 10.1016/J.Jalz.2018.06.782  0.781
2006 Rice HC, Wierda KD, Frere S, Vertkin I, Van Molle I, Ranaivoson F, Comoletti D, Savas JN, Slutsky I, De Strooper B, de Wit J. P1-185: SECRETED AMYLOID PRECURSOR PROTEIN IS A GABABR1A LIGAND THAT SUPPRESSES SYNAPTIC VESICLE RELEASE Alzheimer's & Dementia. 14: P349-P349. DOI: 10.1016/J.Jalz.2018.06.189  0.375
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