| Year |
Citation |
Score |
| 2024 |
Wahl N, Espeso-Gil S, Chietera P, Nagel A, Laighneach A, Morris DW, Rajarajan P, Akbarian S, Dechant G, Apostolova G. SATB2 organizes the 3D genome architecture of cognition in cortical neurons. Molecular Cell. PMID 38244545 DOI: 10.1016/j.molcel.2023.12.024 |
0.424 |
|
| 2023 |
Tandon R, Nasrallah H, Akbarian S, Carpenter WT, DeLisi LE, Gaebel W, Green MF, Gur RE, Heckers S, Kane JM, Malaspina D, Meyer-Lindenberg A, Murray R, Owen M, Smoller JW, et al. The schizophrenia syndrome, circa 2024: What we know and how that informs its nature. Schizophrenia Research. 264: 1-28. PMID 38086109 DOI: 10.1016/j.schres.2023.11.015 |
0.361 |
|
| 2023 |
Garrison MA, Jang Y, Bae T, Cherskov A, Emery SB, Fasching L, Jones A, Moldovan JB, Molitor C, Pochareddy S, Peters MA, Shin JH, Wang Y, Yang X, Akbarian S, et al. Genomic data resources of the Brain Somatic Mosaicism Network for neuropsychiatric diseases. Scientific Data. 10: 813. PMID 37985666 DOI: 10.1038/s41597-023-02645-7 |
0.346 |
|
| 2023 |
Wei J, Lambert TY, Valada A, Patel N, Walker K, Lenders J, Schmidt CJ, Iskhakova M, Alazizi A, Mair-Meijers H, Mash DC, Luca F, Pique-Regi R, Bannon MJ, Akbarian S. Single nucleus transcriptomics of ventral midbrain identifies glial activation associated with chronic opioid use disorder. Nature Communications. 14: 5610. PMID 37699936 DOI: 10.1038/s41467-023-41455-8 |
0.319 |
|
| 2023 |
Maury EA, Sherman MA, Genovese G, Gilgenast TG, Kamath T, Burris SJ, Rajarajan P, Flaherty E, Akbarian S, Chess A, McCarroll SA, Loh PR, Phillips-Cremins JE, Brennand KJ, Macosko EZ, et al. Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent and disruptions. Cell Genomics. 3: 100356. PMID 37601975 DOI: 10.1016/j.xgen.2023.100356 |
0.328 |
|
| 2023 |
Powell SK, Liao W, O'Shea C, Kammourh S, Ghorbani S, Rigat R, Elahi R, Deans PM, Le DJ, Agarwal P, Seow WQ, Wang KC, Akbarian S, Brennand KJ. Schizophrenia Risk Mapping and Functional Engineering of the 3D Genome in Three Neuronal Subtypes. Biorxiv : the Preprint Server For Biology. PMID 37502907 DOI: 10.1101/2023.07.17.549339 |
0.419 |
|
| 2022 |
Plaza-Jennings A, Valada A, Akbarian S. 3D Genome Plasticity in Normal and Diseased Neurodevelopment. Genes. 13. PMID 36360237 DOI: 10.3390/genes13111999 |
0.369 |
|
| 2022 |
Girdhar K, Hoffman GE, Bendl J, Rahman S, Dong P, Liao W, Hauberg ME, Sloofman L, Brown L, Devillers O, Kassim BS, Wiseman JR, Park R, Zharovsky E, Jacobov R, ... ... Akbarian S, et al. Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains. Nature Neuroscience. PMID 35332326 DOI: 10.1038/s41593-022-01032-6 |
0.734 |
|
| 2022 |
Rapanelli M, Williams JB, Ma K, Yang F, Zhong P, Patel R, Kumar M, Qin L, Rein B, Wang ZJ, Kassim B, Javidfar B, Couto L, Akbarian S, Yan Z. Targeting histone demethylase LSD1 for treatment of deficits in autism mouse models. Molecular Psychiatry. PMID 35296809 DOI: 10.1038/s41380-022-01508-8 |
0.368 |
|
| 2021 |
Chandrasekaran S, Espeso-Gil S, Loh YE, Javidfar B, Kassim B, Zhu Y, Zhang Y, Dong Y, Bicks LK, Li H, Rajarajan P, Peter CJ, Sun D, Agullo-Pascual E, Iskhakova M, ... ... Akbarian S, et al. Neuron-specific chromosomal megadomain organization is adaptive to recent retrotransposon expansions. Nature Communications. 12: 7243. PMID 34903713 DOI: 10.1038/s41467-021-26862-z |
0.3 |
|
| 2021 |
Dobrindt K, Zhang H, Das D, Abdollahi S, Prorok T, Ghosh S, Weintraub S, Genovese G, Powell SK, Lund A, Akbarian S, Eggan K, McCarroll S, Duan J, Avramopoulos D, et al. Publicly Available hiPSC Lines with Extreme Polygenic Risk Scores for Modeling Schizophrenia. Complex Psychiatry. 6: 68-82. PMID 34883504 DOI: 10.1159/000512716 |
0.352 |
|
| 2021 |
Powell SK, O'Shea C, Townsley K, Prytkova I, Dobrindt K, Elahi R, Iskhakova M, Lambert T, Valada A, Liao W, Ho SM, Slesinger PA, Huckins LM, Akbarian S, Brennand KJ. Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk. Molecular Psychiatry. PMID 34493831 DOI: 10.1038/s41380-021-01273-0 |
0.337 |
|
| 2021 |
Hu B, Won H, Mah W, Park RB, Kassim B, Spiess K, Kozlenkov A, Crowley CA, Pochareddy S, Li Y, Dracheva S, Sestan N, Akbarian S, Geschwind DH. Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders. Nature Communications. 12: 3968. PMID 34172755 DOI: 10.1038/s41467-021-24243-0 |
0.451 |
|
| 2021 |
Espeso-Gil S, Holik AZ, Bonnin S, Jhanwar S, Chandrasekaran S, Pique-Regi R, Albaigès-Ràfols J, Maher M, Permanyer J, Irimia M, Friedländer MR, Pons-Espinal M, Akbarian S, Dierssen M, Maass PG, et al. Environmental Enrichment Induces Epigenomic and Genome Organization Changes Relevant for Cognition. Frontiers in Molecular Neuroscience. 14: 664912. PMID 34025350 DOI: 10.3389/fnmol.2021.664912 |
0.346 |
|
| 2020 |
Powell SK, O'Shea C, Brennand KJ, Akbarian S. Parsing the Functional Impact of Noncoding Genetic Variants in the Brain Epigenome. Biological Psychiatry. PMID 33131715 DOI: 10.1016/j.biopsych.2020.06.033 |
0.661 |
|
| 2020 |
Dobrindt K, Hoagland DA, Seah C, Kassim B, O'Shea CP, Iskhakova M, Fernando MB, Deans PJM, Powell SK, Javidfar B, Murphy A, Peter C, Møeller R, Garcia MF, Kimura M, ... ... Akbarian S, et al. Common genetic variation in humans impacts susceptibility to SARS-CoV-2 infection. Biorxiv : the Preprint Server For Biology. PMID 32995783 DOI: 10.1101/2020.09.20.300574 |
0.545 |
|
| 2020 |
Powell SK, O'Shea CP, Shannon SR, Akbarian S, Brennand KJ. Investigation of Schizophrenia with Human Induced Pluripotent Stem Cells. Advances in Neurobiology. 25: 155-206. PMID 32578147 DOI: 10.1007/978-3-030-45493-7_6 |
0.643 |
|
| 2020 |
Sey NYA, Hu B, Mah W, Fauni H, McAfee JC, Rajarajan P, Brennand KJ, Akbarian S, Won H. A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles. Nature Neuroscience. PMID 32152537 DOI: 10.1038/S41593-020-0603-0 |
0.652 |
|
| 2020 |
Espeso-Gil S, Halene T, Bendl J, Kassim B, Ben Hutta G, Iskhakova M, Shokrian N, Auluck P, Javidfar B, Rajarajan P, Chandrasekaran S, Peter CJ, Cote A, Birnbaum R, Liao W, ... ... Akbarian S, et al. A chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons. Genome Medicine. 12: 19. PMID 32075678 DOI: 10.1186/S13073-020-0715-X |
0.33 |
|
| 2019 |
Rajarajan P, Akbarian S. Use of the epigenetic toolbox
to contextualize common variants associated with schizophrenia risk
. Dialogues in Clinical Neuroscience. 21: 407-416. PMID 31949408 DOI: 10.31887/Dcns.2019.21.4/Sakbarian |
0.426 |
|
| 2019 |
Gusev FE, Reshetov DA, Mitchell AC, Andreeva TV, Dincer A, Grigorenko AP, Fedonin G, Halene T, Aliseychik M, Filippova E, Weng Z, Akbarian S, Rogaev EI. Chromatin profiling of cortical neurons identifies individual epigenetic signatures in schizophrenia. Translational Psychiatry. 9: 256. PMID 31624234 DOI: 10.1038/S41398-019-0596-1 |
0.738 |
|
| 2019 |
Hoffman GE, Bendl J, Voloudakis G, Montgomery KS, Sloofman L, Wang YC, Shah HR, Hauberg ME, Johnson JS, Girdhar K, Song L, Fullard JF, Kramer R, Hahn CG, Gur R, ... ... Akbarian S, et al. CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder. Scientific Data. 6: 180. PMID 31551426 DOI: 10.1038/S41597-019-0183-6 |
0.392 |
|
| 2019 |
Peter CJ, Saito A, Hasegawa Y, Tanaka Y, Nagpal M, Perez G, Alway E, Espeso-Gil S, Fayyad T, Ratner C, Dincer A, Gupta A, Devi L, Pappas JG, Lalonde FM, ... ... Akbarian S, et al. In vivo epigenetic editing of Sema6a promoter reverses transcallosal dysconnectivity caused by C11orf46/Arl14ep risk gene. Nature Communications. 10: 4112. PMID 31511512 DOI: 10.1038/S41467-019-12013-Y |
0.385 |
|
| 2019 |
Rajarajan P, Flaherty E, Akbarian S, Brennand KJ. CRISPR-based functional evaluation of schizophrenia risk variants. Schizophrenia Research. PMID 31277978 DOI: 10.1016/J.Schres.2019.06.017 |
0.656 |
|
| 2019 |
Rajarajan P, Borrman T, Liao W, Espeso-Gil S, Chandrasekaran S, Jiang Y, Weng Z, Brennand KJ, Akbarian S. Spatial genome exploration in the context of cognitive and neurological disease. Current Opinion in Neurobiology. 59: 112-119. PMID 31255842 DOI: 10.1016/J.Conb.2019.05.007 |
0.655 |
|
| 2019 |
Gusev FE, Reshetov DA, Mitchell AC, Andreeva TV, Dincer A, Grigorenko AP, Fedonin G, Halene T, Aliseychik M, Goltsov AY, Solovyev V, Brizgalov L, Filippova E, Weng Z, Akbarian S, et al. Epigenetic-genetic chromatin footprinting identifies novel and subject-specific genes active in prefrontal cortex neurons. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802646R. PMID 30970224 DOI: 10.1096/Fj.201802646R |
0.717 |
|
| 2018 |
Wang D, Liu S, Warrell J, Won H, Shi X, Navarro FCP, Clarke D, Gu M, Emani P, Yang YT, Xu M, Gandal MJ, Lou S, Zhang J, Park JJ, ... ... Akbarian S, et al. Comprehensive functional genomic resource and integrative model for the human brain. Science (New York, N.Y.). 362. PMID 30545857 DOI: 10.1126/Science.Aat8464 |
0.411 |
|
| 2018 |
Rajarajan P, Borrman T, Liao W, Schrode N, Flaherty E, Casiño C, Powell S, Yashaswini C, LaMarca EA, Kassim B, Javidfar B, Espeso-Gil S, Li A, Won H, Geschwind DH, ... ... Akbarian S, et al. Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk. Science (New York, N.Y.). 362. PMID 30545851 DOI: 10.1126/Science.Aat4311 |
0.685 |
|
| 2018 |
Bryois J, Garrett ME, Song L, Safi A, Giusti-Rodriguez P, Johnson GD, Shieh AW, Buil A, Fullard JF, Roussos P, Sklar P, Akbarian S, Haroutunian V, Stockmeier CA, Wray GA, et al. Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia. Nature Communications. 9: 3121. PMID 30087329 DOI: 10.1038/S41467-018-05379-Y |
0.423 |
|
| 2018 |
Girdhar K, Hoffman GE, Jiang Y, Brown L, Kundakovic M, Hauberg ME, Francoeur NJ, Wang YC, Shah H, Kavanagh DH, Zharovsky E, Jacobov R, Wiseman JR, Park R, Johnson JS, ... ... Akbarian S, et al. Cell-specific histone modification maps in the human frontal lobe link schizophrenia risk to the neuronal epigenome. Nature Neuroscience. PMID 30038276 DOI: 10.1038/S41593-018-0187-0 |
0.738 |
|
| 2018 |
Rajarajan P, Jiang Y, Kassim BS, Akbarian S. Chromosomal Conformations and Epigenomic Regulation in Schizophrenia. Progress in Molecular Biology and Translational Science. 157: 21-40. PMID 29933951 DOI: 10.1016/Bs.Pmbts.2017.11.022 |
0.49 |
|
| 2018 |
Mao W, Salzberg AC, Uchigashima M, Hasegawa Y, Hock H, Watanabe M, Akbarian S, Kawasawa YI, Futai K. Activity-Induced Regulation of Synaptic Strength through the Chromatin Reader L3mbtl1. Cell Reports. 23: 3209-3222. PMID 29898393 DOI: 10.1016/J.Celrep.2018.05.028 |
0.318 |
|
| 2018 |
Dobbyn A, Huckins LM, Boocock J, Sloofman LG, Glicksberg BS, Giambartolomei C, Hoffman GE, Perumal TM, Girdhar K, Jiang Y, Raj T, Ruderfer DM, Kramer RS, Pinto D, ... Akbarian S, et al. Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS. American Journal of Human Genetics. PMID 29805045 DOI: 10.1016/J.Ajhg.2018.04.011 |
0.367 |
|
| 2018 |
LaMarca EA, Powell SK, Akbarian S, Brennand KJ. Modeling Neuropsychiatric and Neurodegenerative Diseases With Induced Pluripotent Stem Cells. Frontiers in Pediatrics. 6: 82. PMID 29666786 DOI: 10.3389/Fped.2018.00082 |
0.576 |
|
| 2017 |
Ibi D, de la Fuente Revenga M, Kezunovic N, Muguruza C, Saunders JM, Gaitonde SA, Moreno JL, Ijaz MK, Santosh V, Kozlenkov A, Holloway T, Seto J, García-Bea A, Kurita M, Mosley GE, ... ... Akbarian S, et al. Antipsychotic-induced Hdac2 transcription via NF-κB leads to synaptic and cognitive side effects. Nature Neuroscience. PMID 28783139 DOI: 10.1038/Nn.4616 |
0.307 |
|
| 2017 |
Ho SM, Hartley BJ, Flaherty E, Rajarajan P, Abdelaal R, Obiorah I, Barretto N, Muhammad H, Phatnani HP, Akbarian S, Brennand KJ. Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes. Stem Cell Reports. PMID 28757163 DOI: 10.1016/J.Stemcr.2017.06.012 |
0.632 |
|
| 2017 |
Javidfar B, Park R, Kassim BS, Bicks LK, Akbarian S. The epigenomics of schizophrenia, in the mouse. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 28699694 DOI: 10.1002/ajmg.b.32566 |
0.47 |
|
| 2017 |
Jiang Y, Loh YE, Rajarajan P, Hirayama T, Liao W, Kassim BS, Javidfar B, Hartley BJ, Kleofas L, Park RB, Labonte B, Ho SM, Chandrasekaran S, Do C, Ramirez BR, ... ... Akbarian S, et al. The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain. Nature Genetics. PMID 28671686 DOI: 10.1038/Ng.3906 |
0.674 |
|
| 2017 |
Engmann O, Labonté B, Mitchell A, Bashtrykov P, Calipari ES, Rosenbluh C, Loh YE, Walker DM, Burek D, Hamilton PJ, Issler O, Neve RL, Turecki G, Hurd Y, Chess A, ... ... Akbarian S, et al. Cocaine-Induced Chromatin Modifications Associate With Increased Expression and Three-Dimensional Looping of Auts2. Biological Psychiatry. PMID 28577753 DOI: 10.1016/J.Biopsych.2017.04.013 |
0.652 |
|
| 2017 |
McConnell MJ, Moran JV, Abyzov A, Akbarian S, Bae T, Cortes-Ciriano I, Erwin JA, Fasching L, Flasch DA, Freed D, Ganz J, Jaffe AE, Kwan KY, Kwon M, Lodato MA, et al. Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network. Science (New York, N.Y.). 356. PMID 28450582 DOI: 10.1126/Science.Aal1641 |
0.383 |
|
| 2016 |
Rajarajan P, Gil SE, Brennand KJ, Akbarian S. Spatial genome organization and cognition. Nature Reviews. Neuroscience. PMID 27708356 DOI: 10.1038/Nrn.2016.124 |
0.623 |
|
| 2016 |
Liu X, Han D, Somel M, Jiang X, Hu H, Guijarro P, Zhang N, Mitchell A, Halene T, Ely JJ, Sherwood CC, Hof PR, Qiu Z, Pääbo S, Akbarian S, et al. Disruption of an Evolutionarily Novel Synaptic Expression Pattern in Autism. Plos Biology. 14: e1002558. PMID 27685936 DOI: 10.1371/Journal.Pbio.1002558 |
0.671 |
|
| 2016 |
Mitchell AC, Javidfar B, Bicks LK, Neve R, Garbett K, Lander SS, Mirnics K, Morishita H, Wood MA, Jiang Y, Gaisler-Salomon I, Akbarian S. Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex. Nature Communications. 7: 12743. PMID 27597321 DOI: 10.1038/Ncomms12743 |
0.702 |
|
| 2016 |
Shen EY, Jiang Y, Javidfar B, Kassim B, Loh YH, Ma Q, Mitchell AC, Pothula V, Stewart AF, Ernst P, Yao WD, Martin G, Shen L, Jakovcevski M, Akbarian S. Neuronal Deletion of Kmt2a/Mll1 Histone Methyltransferase in Ventral Striatum is Associated with Defective Spike-Timing Dependent Striatal Synaptic Plasticity, Altered Response to Dopaminergic Drugs and Increased Anxiety. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27485686 DOI: 10.1038/Npp.2016.144 |
0.689 |
|
| 2016 |
Peter CJ, Fischer LK, Kundakovic M, Garg P, Jakovcevski M, Dincer A, Amaral AC, Ginns EI, Galdzicka M, Bryce CP, Ratner C, Waber DP, Mokler D, Medford G, Champagne FA, ... ... Akbarian S, et al. DNA Methylation Signatures of Early Childhood Malnutrition Associated With Impairments in Attention and Cognition. Biological Psychiatry. PMID 27184921 DOI: 10.1016/J.Biopsych.2016.03.2100 |
0.704 |
|
| 2016 |
Kundakovic M, Jiang Y, Kavanagh DH, Dincer A, Brown L, Pothula V, Zharovsky E, Park R, Jacobov R, Magro I, Kassim B, Wiseman J, Dang K, Sieberts SK, Roussos P, ... ... Akbarian S, et al. Practical Guidelines for High-Resolution Epigenomic Profiling of Nucleosomal Histones in Postmortem Human Brain Tissue. Biological Psychiatry. PMID 27113501 DOI: 10.1016/J.Biopsych.2016.03.1048 |
0.724 |
|
| 2016 |
Fullard JF, Halene TB, Giambartolomei C, Haroutunian V, Akbarian S, Roussos P. Understanding the genetic liability to schizophrenia through the neuroepigenome. Schizophrenia Research. PMID 26827128 DOI: 10.1016/J.Schres.2016.01.039 |
0.43 |
|
| 2016 |
Halene TB, Kozlenkov A, Jiang Y, Mitchell AC, Javidfar B, Dincer A, Park R, Wiseman J, Croxson PL, Giannaris EL, Hof PR, Roussos P, Dracheva S, Hemby SE, Akbarian S. NeuN(+) neuronal nuclei in non-human primate prefrontal cortex and subcortical white matter after clozapine exposure. Schizophrenia Research. PMID 26776227 DOI: 10.1016/J.Schres.2015.12.016 |
0.668 |
|
| 2015 |
Labadorf A, Hoss AG, Lagomarsino V, Latourelle JC, Hadzi TC, Bregu J, MacDonald ME, Gusella JF, Chen JF, Akbarian S, Weng Z, Myers RH. RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression. Plos One. 10: e0143563. PMID 26636579 DOI: 10.1371/Journal.Pone.0143563 |
0.362 |
|
| 2015 |
Dong X, Tsuji J, Labadorf A, Roussos P, Chen JF, Myers RH, Akbarian S, Weng Z. The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington's Disease. Plos One. 10: e0144398. PMID 26636336 DOI: 10.1371/Journal.Pone.0144398 |
0.37 |
|
| 2015 |
Akbarian S, Liu C, Knowles JA, Vaccarino FM, Farnham PJ, Crawford GE, Jaffe AE, Pinto D, Dracheva S, Geschwind DH, Mill J, Nairn AC, Abyzov A, Pochareddy S, Prabhakar S, et al. The PsychENCODE project. Nature Neuroscience. 18: 1707-1712. PMID 26605881 DOI: 10.1038/Nn.4156 |
0.737 |
|
| 2015 |
Akbarian S, Kundakovic M. CHRNA7 and CHRFAM7A: Psychosis and Smoking? Blame the Neighbors! The American Journal of Psychiatry. 172: 1054-6. PMID 26575444 DOI: 10.1176/Appi.Ajp.2015.15081018 |
0.745 |
|
| 2015 |
Jakovcevski M, Akbarian S, Di Benedetto B. Pharmacological modulation of astrocytes and the role of cell type-specific histone modifications for the treatment of mood disorders. Current Opinion in Pharmacology. 26: 61-6. PMID 26515273 DOI: 10.1016/j.coph.2015.10.002 |
0.343 |
|
| 2015 |
Nestler EJ, Peña CJ, Kundakovic M, Mitchell A, Akbarian S. Epigenetic Basis of Mental Illness. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. PMID 26450593 DOI: 10.1177/1073858415608147 |
0.784 |
|
| 2015 |
Maze I, Wenderski W, Noh KM, Bagot RC, Tzavaras N, Purushothaman I, Elsässer SJ, Guo Y, Ionete C, Hurd YL, Tamminga CA, Halene T, Farrelly L, Soshnev AA, Wen D, ... ... Akbarian S, et al. Critical Role of Histone Turnover in Neuronal Transcription and Plasticity. Neuron. 87: 77-94. PMID 26139371 DOI: 10.1016/J.Neuron.2015.06.014 |
0.403 |
|
| 2015 |
Mahajan S, Crisci J, Wong A, Akbarian S, Foll M, Jensen JD. Quantifying polymorphism and divergence from epigenetic data: a framework for inferring the action of selection. Frontiers in Genetics. 6: 190. PMID 26074949 DOI: 10.3389/Fgene.2015.00190 |
0.361 |
|
| 2015 |
Shen EY, Jiang Y, Mao W, Futai K, Hock H, Akbarian S. Cognition and mood-related behaviors in L3mbtl1 null mutant mice. Plos One. 10: e0121252. PMID 25849281 DOI: 10.1371/Journal.Pone.0121252 |
0.327 |
|
| 2015 |
Morishita H, Kundakovic M, Bicks L, Mitchell A, Akbarian S. Interneuron epigenomes during the critical period of cortical plasticity: Implications for schizophrenia. Neurobiology of Learning and Memory. PMID 25849095 DOI: 10.1016/J.Nlm.2015.03.005 |
0.803 |
|
| 2015 |
Jakovcevski M, Ruan H, Shen EY, Dincer A, Javidfar B, Ma Q, Peter CJ, Cheung I, Mitchell AC, Jiang Y, Lin CL, Pothula V, Stewart AF, Ernst P, Yao WD, ... Akbarian S, et al. Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5097-108. PMID 25834037 DOI: 10.1523/Jneurosci.3004-14.2015 |
0.69 |
|
| 2015 |
Hess JL, Quinn TP, Akbarian S, Glatt SJ. Bioinformatic analyses and conceptual synthesis of evidence linking ZNF804A to risk for schizophrenia and bipolar disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 168: 14-35. PMID 25522715 DOI: 10.1002/Ajmg.B.32284 |
0.396 |
|
| 2015 |
Bai G, Cheung I, Shulha HP, Coelho JE, Li P, Dong X, Jakovcevski M, Wang Y, Grigorenko A, Jiang Y, Hoss A, Patel K, Zheng M, Rogaev E, Myers RH, ... ... Akbarian S, et al. Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains. Human Molecular Genetics. 24: 1441-56. PMID 25480889 DOI: 10.1093/Hmg/Ddu561 |
0.432 |
|
| 2015 |
Akbarian S. Epigenetic mechanisms in schizophrenia. Dialogues in Clinical Neuroscience. 16: 405-17. PMID 25364289 |
0.483 |
|
| 2015 |
Shen EY, Ahern TH, Cheung I, Straubhaar J, Dincer A, Houston I, de Vries GJ, Akbarian S, Forger NG. Epigenetics and sex differences in the brain: A genome-wide comparison of histone-3 lysine-4 trimethylation (H3K4me3) in male and female mice. Experimental Neurology. 268: 21-9. PMID 25131640 DOI: 10.1016/J.Expneurol.2014.08.006 |
0.319 |
|
| 2014 |
Bharadwaj R, Peter CJ, Jiang Y, Roussos P, Vogel-Ciernia A, Shen EY, Mitchell AC, Mao W, Whittle C, Dincer A, Jakovcevski M, Pothula V, Rasmussen TP, Giakoumaki SG, Bitsios P, ... ... Akbarian S, et al. Conserved higher-order chromatin regulates NMDA receptor gene expression and cognition. Neuron. 84: 997-1008. PMID 25467983 DOI: 10.1016/J.Neuron.2014.10.032 |
0.688 |
|
| 2014 |
Mitchell AC, Jiang Y, Peter C, Akbarian S. Transcriptional regulation of GAD1 GABA synthesis gene in the prefrontal cortex of subjects with schizophrenia. Schizophrenia Research. PMID 25458568 DOI: 10.1016/j.schres.2014.10.020 |
0.732 |
|
| 2014 |
Roussos P, Mitchell AC, Voloudakis G, Fullard JF, Pothula VM, Tsang J, Stahl EA, Georgakopoulos A, Ruderfer DM, Charney A, Okada Y, Siminovitch KA, Worthington J, Padyukov L, Klareskog L, ... ... Akbarian S, et al. A role for noncoding variation in schizophrenia. Cell Reports. 9: 1417-29. PMID 25453756 DOI: 10.1016/J.Celrep.2014.10.015 |
0.773 |
|
| 2014 |
Mitchell A, Roussos P, Peter C, Tsankova N, Akbarian S. The future of neuroepigenetics in the human brain. Progress in Molecular Biology and Translational Science. 128: 199-228. PMID 25410546 DOI: 10.1016/B978-0-12-800977-2.00008-5 |
0.739 |
|
| 2014 |
Maze I, Shen L, Zhang B, Garcia BA, Shao N, Mitchell A, Sun H, Akbarian S, Allis CD, Nestler EJ. Analytical tools and current challenges in the modern era of neuroepigenomics. Nature Neuroscience. 17: 1476-90. PMID 25349914 DOI: 10.1038/Nn.3816 |
0.667 |
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| 2014 |
Shen E, Shulha H, Weng Z, Akbarian S. Regulation of histone H3K4 methylation in brain development and disease. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369. PMID 25135975 DOI: 10.1098/Rstb.2013.0514 |
0.44 |
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| 2014 |
Mitchell AC, Bharadwaj R, Whittle C, Krueger W, Mirnics K, Hurd Y, Rasmussen T, Akbarian S. The genome in three dimensions: a new frontier in human brain research. Biological Psychiatry. 75: 961-9. PMID 23958183 DOI: 10.1016/J.Biopsych.2013.07.015 |
0.731 |
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| 2013 |
Bharadwaj R, Jiang Y, Mao W, Jakovcevski M, Dincer A, Krueger W, Garbett K, Whittle C, Tushir JS, Liu J, Sequeira A, Vawter MP, Gardner PD, Casaccia P, Rasmussen T, ... ... Akbarian S, et al. Conserved chromosome 2q31 conformations are associated with transcriptional regulation of GAD1 GABA synthesis enzyme and altered in prefrontal cortex of subjects with schizophrenia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 11839-51. PMID 23864674 DOI: 10.1523/Jneurosci.1252-13.2013 |
0.462 |
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| 2013 |
Jakovcevski M, Bharadwaj R, Straubhaar J, Gao G, Gavin DP, Jakovcevski I, Mitchell AC, Akbarian S. Prefrontal cortical dysfunction after overexpression of histone deacetylase 1. Biological Psychiatry. 74: 696-705. PMID 23664640 DOI: 10.1016/J.Biopsych.2013.03.020 |
0.7 |
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| 2013 |
Shulha HP, Cheung I, Guo Y, Akbarian S, Weng Z. Coordinated cell type-specific epigenetic remodeling in prefrontal cortex begins before birth and continues into early adulthood. Plos Genetics. 9: e1003433. PMID 23593028 DOI: 10.1371/Journal.Pgen.1003433 |
0.383 |
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| 2013 |
Akbarian S, Beeri MS, Haroutunian V. Epigenetic determinants of healthy and diseased brain aging and cognition. Jama Neurology. 70: 711-8. PMID 23571692 DOI: 10.1001/Jamaneurol.2013.1459 |
0.306 |
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| 2013 |
Hasan A, Mitchell A, Schneider A, Halene T, Akbarian S. Epigenetic dysregulation in schizophrenia: molecular and clinical aspects of histone deacetylase inhibitors. European Archives of Psychiatry and Clinical Neuroscience. 263: 273-84. PMID 23381549 DOI: 10.1007/s00406-013-0395-2 |
0.684 |
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| 2013 |
Akbarian S, Nestler EJ. Epigenetic mechanisms in psychiatry. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1-2. PMID 23147478 DOI: 10.1038/npp.2012.185 |
0.46 |
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| 2013 |
Houston I, Peter CJ, Mitchell A, Straubhaar J, Rogaev E, Akbarian S. Epigenetics in the human brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 183-97. PMID 22643929 DOI: 10.1038/npp.2012.78 |
0.744 |
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| 2012 |
Shulha HP, Crisci JL, Reshetov D, Tushir JS, Cheung I, Bharadwaj R, Chou HJ, Houston IB, Peter CJ, Mitchell AC, Yao WD, Myers RH, Chen JF, Preuss TM, Rogaev EI, ... ... Akbarian S, et al. Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. Plos Biology. 10: e1001427. PMID 23185133 DOI: 10.1371/Journal.Pbio.1001427 |
0.734 |
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| 2012 |
Jakovcevski M, Akbarian S. Epigenetic mechanisms in neurological disease. Nature Medicine. 18: 1194-204. PMID 22869198 DOI: 10.1038/nm.2828 |
0.337 |
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| 2012 |
Connor CM, Dincer A, Straubhaar J, Galler JR, Houston IB, Akbarian S. Maternal immune activation alters behavior in adult offspring, with subtle changes in the cortical transcriptome and epigenome. Schizophrenia Research. 140: 175-84. PMID 22804924 DOI: 10.1016/J.Schres.2012.06.037 |
0.356 |
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| 2012 |
Gavin DP, Akbarian S. Epigenetic and post-transcriptional dysregulation of gene expression in schizophrenia and related disease. Neurobiology of Disease. 46: 255-62. PMID 22182689 DOI: 10.1016/J.Nbd.2011.12.008 |
0.423 |
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| 2012 |
Shulha HP, Cheung I, Whittle C, Wang J, Virgil D, Lin CL, Guo Y, Lessard A, Akbarian S, Weng Z. Epigenetic signatures of autism: trimethylated H3K4 landscapes in prefrontal neurons. Archives of General Psychiatry. 69: 314-24. PMID 22065254 DOI: 10.1001/Archgenpsychiatry.2011.151 |
0.329 |
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| 2011 |
Peter CJ, Akbarian S. Balancing histone methylation activities in psychiatric disorders. Trends in Molecular Medicine. 17: 372-9. PMID 21429800 DOI: 10.1016/j.molmed.2011.02.003 |
0.428 |
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| 2011 |
Akbarian S. Epigenetics of schizophrenia. Current Topics in Behavioral Neurosciences. 4: 611-28. PMID 21312415 DOI: 10.1007/7854_2010_38 |
0.466 |
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| 2011 |
Connor CM, Crawford BC, Akbarian S. White matter neuron alterations in schizophrenia and related disorders. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 29: 325-34. PMID 20691252 DOI: 10.1016/j.ijdevneu.2010.07.236 |
0.36 |
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| 2010 |
Jiang Y, Matevossian A, Guo Y, Akbarian S. Setdb1-mediated histone H3K9 hypermethylation in neurons worsens the neurological phenotype of Mecp2-deficient mice. Neuropharmacology. 60: 1088-97. PMID 20869373 DOI: 10.1016/j.neuropharm.2010.09.020 |
0.37 |
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| 2010 |
Jiang Y, Jakovcevski M, Bharadwaj R, Connor C, Schroeder FA, Lin CL, Straubhaar J, Martin G, Akbarian S. Setdb1 histone methyltransferase regulates mood-related behaviors and expression of the NMDA receptor subunit NR2B Journal of Neuroscience. 30: 7152-7167. PMID 20505083 DOI: 10.1523/Jneurosci.1314-10.2010 |
0.327 |
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| 2010 |
Cheung I, Shulha HP, Jiang Y, Matevossian A, Wang J, Weng Z, Akbarian S. Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex. Proceedings of the National Academy of Sciences of the United States of America. 107: 8824-9. PMID 20421462 DOI: 10.1073/Pnas.1001702107 |
0.388 |
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| 2009 |
Akbarian S. The molecular pathology of schizophrenia--focus on histone and DNA modifications. Brain Research Bulletin. 83: 103-7. PMID 19729053 DOI: 10.1016/j.brainresbull.2009.08.018 |
0.446 |
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| 2009 |
Connor CM, Guo Y, Akbarian S. Cingulate White Matter Neurons in Schizophrenia and Bipolar Disorder Biological Psychiatry. 66: 486-493. PMID 19559403 DOI: 10.1016/j.biopsych.2009.04.032 |
0.346 |
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| 2009 |
Mellios N, Huang HS, Baker SP, Galdzicka M, Ginns E, Akbarian S. Molecular determinants of dysregulated GABAergic gene expression in the prefrontal cortex of subjects with schizophrenia. Biological Psychiatry. 65: 1006-14. PMID 19121517 DOI: 10.1016/j.biopsych.2008.11.019 |
0.315 |
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| 2009 |
Akbarian S, Huang HS. Epigenetic Regulation in Human Brain-Focus on Histone Lysine Methylation Biological Psychiatry. 65: 198-203. PMID 18814864 DOI: 10.1016/j.biopsych.2008.08.015 |
0.424 |
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| 2008 |
Matevossian A, Akbarian S. Neuronal nuclei isolation from human postmortem brain tissue. Journal of Visualized Experiments : Jove. PMID 19078943 DOI: 10.3791/914 |
0.335 |
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| 2008 |
Matevossian A, Akbarian S. A chromatin assay for human brain tissue. Journal of Visualized Experiments : Jove. PMID 19066569 DOI: 10.3791/717 |
0.411 |
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| 2008 |
Jiang Y, Langley B, Lubin FD, Renthal W, Wood MA, Yasui DH, Kumar A, Nestler EJ, Akbarian S, Beckel-Mitchener AC. Epigenetics in the nervous system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11753-9. PMID 19005036 DOI: 10.1523/Jneurosci.3797-08.2008 |
0.352 |
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| 2008 |
Jiang Y, Matevossian A, Huang HS, Straubhaar J, Akbarian S. Isolation of neuronal chromatin from brain tissue. Bmc Neuroscience. 9: 42. PMID 18442397 DOI: 10.1186/1471-2202-9-42 |
0.339 |
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| 2008 |
Connor CM, Akbarian S. DNA methylation changes in schizophrenia and bipolar disorder Epigenetics. 3: 55-58. PMID 18398310 |
0.41 |
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| 2008 |
Akbarian S, Jiang Y, Laforet G. The molecular pathology of Rett syndrome: synopsis and update. Neuromolecular Medicine. 8: 485-94. PMID 17028371 DOI: 10.1385/NMM:8:4:485 |
0.308 |
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| 2007 |
Huang HS, Matevossian A, Whittle C, Kim SY, Schumacher A, Baker SP, Akbarian S. Prefrontal dysfunction in schizophrenia involves mixed-lineage leukemia 1-regulated histone methylation at GABAergic gene promoters. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11254-62. PMID 17942719 DOI: 10.1523/JNEUROSCI.3272-07.2007 |
0.424 |
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| 2007 |
Siegmund KD, Connor CM, Campan M, Long TI, Weisenberger DJ, Biniszkiewicz D, Jaenisch R, Laird PW, Akbarian S. DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons. Plos One. 2: e895. PMID 17878930 DOI: 10.1371/Journal.Pone.0000895 |
0.333 |
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| 2007 |
Huang HS, Akbarian S. GAD1 mRNA expression and DNA methylation in prefrontal cortex of subjects with schizophrenia Plos One. 2. PMID 17726539 DOI: 10.1371/journal.pone.0000809 |
0.394 |
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| 2006 |
Akbarian S, Huang HS. Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders Brain Research Reviews. 52: 293-304. PMID 16759710 DOI: 10.1016/j.brainresrev.2006.04.001 |
0.396 |
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| 2006 |
Huang HS, Matevossian A, Jiang Y, Akbarian S. Chromatin immunoprecipitation in postmortem brain. Journal of Neuroscience Methods. 156: 284-92. PMID 16574239 DOI: 10.1016/j.jneumeth.2006.02.018 |
0.348 |
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| 2005 |
Akbarian S, Ruehl MG, Bliven E, Luiz LA, Peranelli AC, Baker SP, Roberts RC, Bunney WE, Conley RC, Jones EG, Tamminga CA, Guo Y. Chromatin alterations associated with down-regulated metabolic gene expression in the prefrontal cortex of subjects with schizophrenia. Archives of General Psychiatry. 62: 829-40. PMID 16061760 DOI: 10.1001/Archpsyc.62.8.829 |
0.367 |
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| 2005 |
Stadler F, Kolb G, Rubusch L, Baker SP, Jones EG, Akbarian S. Histone methylation at gene promoters is associated with developmental regulation and region-specific expression of ionotropic and metabotropic glutamate receptors in human brain. Journal of Neurochemistry. 94: 324-36. PMID 15998284 DOI: 10.1111/j.1471-4159.2005.03190.x |
0.364 |
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| 2003 |
Akbarian S. The neurobiology of Rett syndrome. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 9: 57-63. PMID 12580340 DOI: 10.1177/1073858402239591 |
0.378 |
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