| Year |
Citation |
Score |
| 2024 |
Dhaliwal NK, Weng OY, Dong X, Bhattacharya A, Ahmed M, Nishimura H, Choi WWY, Aggarwal A, Luikart BW, Shu Q, Li X, Wilson MD, Moffat J, Wang LY, Muffat J, et al. Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids. Cell Reports. 43: 114173. PMID 38700984 DOI: 10.1016/j.celrep.2024.114173 |
0.41 |
|
| 2023 |
Ahmed M, Muffat J, Li Y. Understanding neural development and diseases using CRISPR screens in human pluripotent stem cell-derived cultures. Frontiers in Cell and Developmental Biology. 11: 1158373. PMID 37101616 DOI: 10.3389/fcell.2023.1158373 |
0.399 |
|
| 2021 |
Bhattacharya A, Choi WWY, Muffat J, Li Y. Modeling developmental brain diseases using human pluripotent stem cell-derived brain organoids - progress and perspective. Journal of Molecular Biology. 167386. PMID 34883115 DOI: 10.1016/j.jmb.2021.167386 |
0.35 |
|
| 2021 |
Dhaliwal N, Choi WWY, Muffat J, Li Y. Modeling PTEN overexpression-induced microcephaly in human brain organoids. Molecular Brain. 14: 131. PMID 34461955 DOI: 10.1186/s13041-021-00841-3 |
0.392 |
|
| 2021 |
Trapecar M, Wogram E, Svoboda D, Communal C, Omer A, Lungjangwa T, Sphabmixay P, Velazquez J, Schneider K, Wright CW, Mildrum S, Hendricks A, Levine S, Muffat J, Lee MJ, et al. Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseases. Science Advances. 7. PMID 33514545 DOI: 10.1126/sciadv.abd1707 |
0.449 |
|
| 2020 |
Tian A, Muffat J, Li Y. Studying Human Neurodevelopment and Diseases Using 3D Brain Organoids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 40: 1186-1193. PMID 32024767 DOI: 10.1523/Jneurosci.0519-19.2019 |
0.343 |
|
| 2019 |
Li Y, Muffat J, Omer Javed A, Keys HR, Lungjangwa T, Bosch I, Khan M, Virgilio MC, Gehrke L, Sabatini DM, Jaenisch R. Genome-wide CRISPR screen for Zika virus resistance in human neural cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 31019072 DOI: 10.1073/Pnas.1900867116 |
0.55 |
|
| 2018 |
Omer Javed A, Li Y, Muffat J, Su KC, Cohen MA, Lungjangwa T, Aubourg P, Cheeseman IM, Jaenisch R. Microcephaly Modeling of Kinetochore Mutation Reveals a Brain-Specific Phenotype. Cell Reports. 25: 368-382.e5. PMID 30304678 DOI: 10.1016/J.Celrep.2018.09.032 |
0.538 |
|
| 2018 |
Muffat J, Li Y, Omer A, Durbin A, Bosch I, Bakiasi G, Richards E, Meyer A, Gehrke L, Jaenisch R. Human induced pluripotent stem cell-derived glial cells and neural progenitors display divergent responses to Zika and dengue infections. Proceedings of the National Academy of Sciences of the United States of America. PMID 29915057 DOI: 10.1073/Pnas.1719266115 |
0.533 |
|
| 2018 |
Liu XS, Wu H, Krzisch M, Wu X, Graef J, Muffat J, Hnisz D, Li CH, Yuan B, Xu C, Li Y, Vershkov D, Cacace A, Young RA, Jaenisch R. Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene. Cell. PMID 29456084 DOI: 10.1016/J.Cell.2018.01.012 |
0.548 |
|
| 2016 |
Li Y, Muffat J, Omer A, Bosch I, Lancaster MA, Sur M, Gehrke L, Knoblich JA, Jaenisch R. Induction of Expansion and Folding in Human Cerebral Organoids. Cell Stem Cell. PMID 28041895 DOI: 10.1016/J.Stem.2016.11.017 |
0.541 |
|
| 2016 |
Muffat J, Li Y, Jaenisch R. CNS disease models with human pluripotent stem cells in the CRISPR age. Current Opinion in Cell Biology. 43: 96-103. PMID 27768957 DOI: 10.1016/J.Ceb.2016.10.001 |
0.609 |
|
| 2016 |
Muffat J, Li Y, Yuan B, Mitalipova M, Omer A, Corcoran S, Bakiasi G, Tsai LH, Aubourg P, Ransohoff RM, Jaenisch R. Efficient derivation of microglia-like cells from human pluripotent stem cells. Nature Medicine. PMID 27668937 DOI: 10.1038/Nm.4189 |
0.588 |
|
| 2014 |
Choi SH, Kim YH, Hebisch M, Sliwinski C, Lee S, D'Avanzo C, Chen H, Hooli B, Asselin C, Muffat J, Klee JB, Zhang C, Wainger BJ, Peitz M, Kovacs DM, et al. A three-dimensional human neural cell culture model of Alzheimer's disease. Nature. 515: 274-8. PMID 25307057 DOI: 10.1038/Nature13800 |
0.679 |
|
| 2014 |
Chudnovsky Y, Kim D, Zheng S, Whyte WA, Bansal M, Bray MA, Gopal S, Theisen MA, Bilodeau S, Thiru P, Muffat J, Yilmaz OH, Mitalipova M, Woolard K, Lee J, et al. ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state. Cell Reports. 6: 313-24. PMID 24440720 DOI: 10.1016/J.Celrep.2013.12.032 |
0.345 |
|
| 2013 |
Chung CY, Khurana V, Auluck PK, Tardiff DF, Mazzulli JR, Soldner F, Baru V, Lou Y, Freyzon Y, Cho S, Mungenast AE, Muffat J, Mitalipova M, Pluth MD, Jui NT, et al. Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons. Science (New York, N.Y.). 342: 983-7. PMID 24158904 DOI: 10.1126/Science.1245296 |
0.662 |
|
| 2013 |
Li Y, Wang H, Muffat J, Cheng AW, Orlando DA, Lovén J, Kwok SM, Feldman DA, Bateup HS, Gao Q, Hockemeyer D, Mitalipova M, Lewis CA, Vander Heiden MG, Sur M, et al. Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons. Cell Stem Cell. 13: 446-58. PMID 24094325 DOI: 10.1016/J.Stem.2013.09.001 |
0.688 |
|
| 2011 |
Saha K, Mei Y, Reisterer CM, Pyzocha NK, Yang J, Muffat J, Davies MC, Alexander MR, Langer R, Anderson DG, Jaenisch R. Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions. Proceedings of the National Academy of Sciences of the United States of America. 108: 18714-9. PMID 22065768 DOI: 10.1073/Pnas.1114854108 |
0.511 |
|
| 2010 |
Lengner CJ, Gimelbrant AA, Erwin JA, Cheng AW, Guenther MG, Welstead GG, Alagappan R, Frampton GM, Xu P, Muffat J, Santagata S, Powers D, Barrett CB, Young RA, Lee JT, et al. Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations. Cell. 141: 872-83. PMID 20471072 DOI: 10.1016/J.Cell.2010.04.010 |
0.607 |
|
| 2010 |
Hanna J, Cheng AW, Saha K, Kim J, Lengner CJ, Soldner F, Cassady JP, Muffat J, Carey BW, Jaenisch R. Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs. Proceedings of the National Academy of Sciences of the United States of America. 107: 9222-7. PMID 20442331 DOI: 10.1073/Pnas.1004584107 |
0.547 |
|
| 2010 |
Muffat J, Walker DW. Apolipoprotein D: an overview of its role in aging and age-related diseases. Cell Cycle (Georgetown, Tex.). 9: 269-73. PMID 20023409 DOI: 10.4161/cc.9.2.10433 |
0.432 |
|
| 2009 |
Hull-Thompson J, Muffat J, Sanchez D, Walker DW, Benzer S, Ganfornina MD, Jasper H. Control of metabolic homeostasis by stress signaling is mediated by the lipocalin NLaz. Plos Genetics. 5: e1000460. PMID 19390610 DOI: 10.1371/Journal.Pgen.1000460 |
0.596 |
|
| 2008 |
Muffat J, Walker DW, Benzer S. Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 105: 7088-93. PMID 18458334 DOI: 10.1073/pnas.0800896105 |
0.635 |
|
| 2006 |
Walker DW, Hájek P, Muffat J, Knoepfle D, Cornelison S, Attardi G, Benzer S. Hypersensitivity to oxygen and shortened lifespan in a Drosophila mitochondrial complex II mutant. Proceedings of the National Academy of Sciences of the United States of America. 103: 16382-7. PMID 17056719 DOI: 10.1073/Pnas.0607918103 |
0.596 |
|
| 2006 |
Walker DW, Muffat J, Rundel C, Benzer S. Overexpression of a Drosophila homolog of apolipoprotein D leads to increased stress resistance and extended lifespan. Current Biology : Cb. 16: 674-9. PMID 16581512 DOI: 10.1016/j.cub.2006.01.057 |
0.629 |
|
| 2003 |
Goldstein LE, Muffat JA, Cherny RA, Moir RD, Ericsson MH, Huang X, Mavros C, Coccia JA, Faget KY, Fitch KA, Masters CL, Tanzi RE, Chylack LT, Bush AI. Cytosolic beta-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease. Lancet. 361: 1258-65. PMID 12699953 DOI: 10.1016/S0140-6736(03)12981-9 |
0.507 |
|
| 2000 |
Goldstein LE, Leopold MC, Huang X, Atwood CS, Saunders AJ, Hartshorn M, Lim JT, Faget KY, Muffat JA, Scarpa RC, Chylack LT, Bowden EF, Tanzi RE, Bush AI. 3-Hydroxykynurenine and 3-hydroxyanthranilic acid generate hydrogen peroxide and promote alpha-crystallin cross-linking by metal ion reduction. Biochemistry. 39: 7266-75. PMID 10852726 DOI: 10.1021/Bi992997S |
0.461 |
|
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