Year |
Citation |
Score |
2024 |
Nishimura H, Li Y. Human pluripotent stem cell-derived models of the hippocampus. The International Journal of Biochemistry & Cell Biology. 106695. PMID 39557338 DOI: 10.1016/j.biocel.2024.106695 |
0.317 |
|
2024 |
Dhaliwal NK, Weng OY, Li Y. Protocol for the efficient and inducible generation of CRISPR-Cas9-edited human cortical neurons from the iCas9-iNgn2 hPSCs. Star Protocols. 5: 103352. PMID 39342621 DOI: 10.1016/j.xpro.2024.103352 |
0.332 |
|
2024 |
Dhaliwal NK, Weng OY, Dong X, Bhattacharya A, Ahmed M, Nishimura H, Choi WWY, Aggarwal A, Luikart BW, Shu Q, Li X, Wilson MD, Moffat J, Wang LY, Muffat J, ... Li Y, et al. Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids. Cell Reports. 43: 114173. PMID 38700984 DOI: 10.1016/j.celrep.2024.114173 |
0.789 |
|
2023 |
Wang WX, Douglas TR, Zhang H, Bhattacharya A, Rothenbroker M, Tang W, Sun Y, Jia Z, Muffat J, Li Y, Chou LYT. Universal, label-free, single-molecule visualization of DNA origami nanodevices across biological samples using origamiFISH. Nature Nanotechnology. PMID 37500778 DOI: 10.1038/s41565-023-01449-5 |
0.65 |
|
2023 |
Ahmed M, Muffat J, Li Y. Understanding neural development and diseases using CRISPR screens in human pluripotent stem cell-derived cultures. Frontiers in Cell and Developmental Biology. 11: 1158373. PMID 37101616 DOI: 10.3389/fcell.2023.1158373 |
0.729 |
|
2021 |
Bhattacharya A, Choi WWY, Muffat J, Li Y. Modeling developmental brain diseases using human pluripotent stem cell-derived brain organoids - progress and perspective. Journal of Molecular Biology. 167386. PMID 34883115 DOI: 10.1016/j.jmb.2021.167386 |
0.713 |
|
2021 |
Dhaliwal N, Choi WWY, Muffat J, Li Y. Modeling PTEN overexpression-induced microcephaly in human brain organoids. Molecular Brain. 14: 131. PMID 34461955 DOI: 10.1186/s13041-021-00841-3 |
0.736 |
|
2021 |
Hu B, Won H, Mah W, Park RB, Kassim B, Spiess K, Kozlenkov A, Crowley CA, Pochareddy S, Li Y, Dracheva S, Sestan N, Akbarian S, Geschwind DH. Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders. Nature Communications. 12: 3968. PMID 34172755 DOI: 10.1038/s41467-021-24243-0 |
0.303 |
|
2020 |
Tian A, Muffat J, Li Y. Studying Human Neurodevelopment and Diseases Using 3D Brain Organoids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 40: 1186-1193. PMID 32024767 DOI: 10.1523/Jneurosci.0519-19.2019 |
0.725 |
|
2019 |
Li Y, Muffat J, Omer Javed A, Keys HR, Lungjangwa T, Bosch I, Khan M, Virgilio MC, Gehrke L, Sabatini DM, Jaenisch R. Genome-wide CRISPR screen for Zika virus resistance in human neural cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 31019072 DOI: 10.1073/Pnas.1900867116 |
0.747 |
|
2018 |
Omer Javed A, Li Y, Muffat J, Su KC, Cohen MA, Lungjangwa T, Aubourg P, Cheeseman IM, Jaenisch R. Microcephaly Modeling of Kinetochore Mutation Reveals a Brain-Specific Phenotype. Cell Reports. 25: 368-382.e5. PMID 30304678 DOI: 10.1016/J.Celrep.2018.09.032 |
0.745 |
|
2018 |
Muffat J, Li Y, Omer A, Durbin A, Bosch I, Bakiasi G, Richards E, Meyer A, Gehrke L, Jaenisch R. Human induced pluripotent stem cell-derived glial cells and neural progenitors display divergent responses to Zika and dengue infections. Proceedings of the National Academy of Sciences of the United States of America. PMID 29915057 DOI: 10.1073/Pnas.1719266115 |
0.746 |
|
2018 |
Mellios N, Feldman DA, Sheridan SD, Ip JPK, Kwok S, Amoah SK, Rosen B, Rodriguez BA, Crawford B, Swaminathan R, Chou S, Li Y, Ziats M, Ernst C, Jaenisch R, et al. Human cerebral organoids reveal deficits in neurogenesis and neuronal migration in MeCP2-deficient neural progenitors. Molecular Psychiatry. 23: 791. PMID 29565043 DOI: 10.1038/Mp.2018.5 |
0.573 |
|
2018 |
Liu XS, Wu H, Krzisch M, Wu X, Graef J, Muffat J, Hnisz D, Li CH, Yuan B, Xu C, Li Y, Vershkov D, Cacace A, Young RA, Jaenisch R. Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene. Cell. PMID 29456084 DOI: 10.1016/J.Cell.2018.01.012 |
0.757 |
|
2017 |
Mellios N, Feldman DA, Sheridan SD, Ip JPK, Kwok S, Amoah SK, Rosen B, Rodriguez BA, Crawford B, Swaminathan R, Chou S, Li Y, Ziats M, Ernst C, Jaenisch R, et al. MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling. Molecular Psychiatry. PMID 28439102 DOI: 10.1038/Mp.2017.86 |
0.55 |
|
2016 |
Li Y, Muffat J, Omer A, Bosch I, Lancaster MA, Sur M, Gehrke L, Knoblich JA, Jaenisch R. Induction of Expansion and Folding in Human Cerebral Organoids. Cell Stem Cell. PMID 28041895 DOI: 10.1016/J.Stem.2016.11.017 |
0.75 |
|
2016 |
Muffat J, Li Y, Jaenisch R. CNS disease models with human pluripotent stem cells in the CRISPR age. Current Opinion in Cell Biology. 43: 96-103. PMID 27768957 DOI: 10.1016/J.Ceb.2016.10.001 |
0.765 |
|
2016 |
Muffat J, Li Y, Yuan B, Mitalipova M, Omer A, Corcoran S, Bakiasi G, Tsai LH, Aubourg P, Ransohoff RM, Jaenisch R. Efficient derivation of microglia-like cells from human pluripotent stem cells. Nature Medicine. PMID 27668937 DOI: 10.1038/Nm.4189 |
0.754 |
|
2015 |
Yu J, Wang L, Akinyi M, Li Y, Duan Z, Zhu Y, Fan G. Danshensu protects isolated heart against ischemia reperfusion injury through activation of Akt/ERK1/2/Nrf2 signaling. International Journal of Clinical and Experimental Medicine. 8: 14793-14804. PMID 26628961 |
0.373 |
|
2015 |
Zhang K, Wang Z, Fan GZ, Wang J, Gao S, Li Y, Sun L, Yin CC, Liu WJ. Two polar residues within C-terminal domain of M1 are critical for the formation of influenza A Virions. Cellular Microbiology. PMID 25939747 DOI: 10.1111/Cmi.12457 |
0.35 |
|
2015 |
Fan GL, Yao Y, Yao L, Li Y. PDCD5 transfection increases cisplatin sensitivity and decreases invasion in hepatic cancer cells. Oncology Letters. 9: 411-417. PMID 25436001 DOI: 10.3892/ol.2014.2645 |
0.426 |
|
2013 |
Li Y, Wang H, Muffat J, Cheng AW, Orlando DA, Lovén J, Kwok SM, Feldman DA, Bateup HS, Gao Q, Hockemeyer D, Mitalipova M, Lewis CA, Vander Heiden MG, Sur M, et al. Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons. Cell Stem Cell. 13: 446-58. PMID 24094325 DOI: 10.1016/J.Stem.2013.09.001 |
0.786 |
|
2013 |
Huang H, Jiang X, Li Z, Li Y, Song CX, He C, Sun M, Chen P, Gurbuxani S, Wang J, Hong GM, Elkahloun AG, Arnovitz S, Wang J, Szulwach K, et al. TET1 plays an essential oncogenic role in MLL-rearranged leukemia. Proceedings of the National Academy of Sciences of the United States of America. 110: 11994-9. PMID 23818607 DOI: 10.1073/Pnas.1310656110 |
0.411 |
|
2013 |
Mo W, Chen J, Patel A, Zhang L, Chau V, Li Y, Cho W, Lim K, Xu J, Lazar AJ, Creighton CJ, Bolshakov S, McKay RM, Lev D, Le LQ, et al. CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors. Cell. 152: 1077-90. PMID 23434321 DOI: 10.1016/J.Cell.2013.01.053 |
0.473 |
|
2012 |
Li Y, Yui D, Luikart BW, McKay RM, Li Y, Rubenstein JL, Parada LF. Conditional ablation of brain-derived neurotrophic factor-TrkB signaling impairs striatal neuron development. Proceedings of the National Academy of Sciences of the United States of America. 109: 15491-6. PMID 22949667 DOI: 10.1073/Pnas.1212899109 |
0.741 |
|
2012 |
Chen J, Li Y, Yu TS, McKay RM, Burns DK, Kernie SG, Parada LF. A restricted cell population propagates glioblastoma growth after chemotherapy. Nature. 488: 522-6. PMID 22854781 DOI: 10.1038/Nature11287 |
0.48 |
|
2012 |
Sanchez-Ortiz E, Yui D, Song D, Li Y, Rubenstein JL, Reichardt LF, Parada LF. TrkA gene ablation in basal forebrain results in dysfunction of the cholinergic circuitry. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 4065-79. PMID 22442072 DOI: 10.1523/Jneurosci.6314-11.2012 |
0.541 |
|
2012 |
Li Y, Li Y, McKay RM, Riethmacher D, Parada LF. Neurofibromin modulates adult hippocampal neurogenesis and behavioral effects of antidepressants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3529-39. PMID 22399775 DOI: 10.1523/Jneurosci.3469-11.2012 |
0.545 |
|
2011 |
Luikart BW, Bensen AL, Washburn EK, Perederiy JV, Su KG, Li Y, Kernie SG, Parada LF, Westbrook GL. miR-132 mediates the integration of newborn neurons into the adult dentate gyrus. Plos One. 6: e19077. PMID 21611182 DOI: 10.1371/Journal.Pone.0019077 |
0.716 |
|
2009 |
Choi SH, Li Y, Parada LF, Sisodia SS. Regulation of hippocampal progenitor cell survival, proliferation and dendritic development by BDNF. Molecular Neurodegeneration. 4: 52. PMID 20025751 DOI: 10.1186/1750-1326-4-52 |
0.562 |
|
2009 |
Chen J, Kwon CH, Lin L, Li Y, Parada LF. Inducible site-specific recombination in neural stem/progenitor cells. Genesis (New York, N.Y. : 2000). 47: 122-31. PMID 19117051 DOI: 10.1002/Dvg.20465 |
0.527 |
|
2009 |
Alcantara Llaguno S, Chen J, Kwon CH, Jackson EL, Li Y, Burns DK, Alvarez-Buylla A, Parada LF. Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer Cell. 15: 45-56. PMID 19111880 DOI: 10.1016/J.Ccr.2008.12.006 |
0.516 |
|
2008 |
Yang FC, Ingram DA, Chen S, Zhu Y, Yuan J, Li X, Yang X, Knowles S, Horn W, Li Y, Zhang S, Yang Y, Vakili ST, Yu M, Burns D, et al. Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow. Cell. 135: 437-48. PMID 18984156 DOI: 10.1016/J.Cell.2008.08.041 |
0.45 |
|
2008 |
Li Y, Luikart BW, Birnbaum S, Chen J, Kwon CH, Kernie SG, Bassel-Duby R, Parada LF. TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment. Neuron. 59: 399-412. PMID 18701066 DOI: 10.1016/J.Neuron.2008.06.023 |
0.733 |
|
2008 |
Kwon CH, Zhao D, Chen J, Alcantara S, Li Y, Burns DK, Mason RP, Lee EY, Wu H, Parada LF. Pten haploinsufficiency accelerates formation of high-grade astrocytomas. Cancer Research. 68: 3286-94. PMID 18451155 DOI: 10.1158/0008-5472.Can-07-6867 |
0.494 |
|
2008 |
Lush ME, Li Y, Kwon CH, Chen J, Parada LF. Neurofibromin is required for barrel formation in the mouse somatosensory cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1580-7. PMID 18272679 DOI: 10.1523/Jneurosci.5236-07.2008 |
0.566 |
|
2008 |
Li Y, Luikart BW, Birnbaum S, Chen J, Kwon CH, Kernie SG, Bassel-Duby R, Parada LF. TrkB Regulates Hippocampal Neurogenesis and Governs Sensitivity to Antidepressive Treatment (DOI:10.1016/j.neuron.2008.06.023) Neuron. 60: 730. DOI: 10.1016/J.Neuron.2008.10.021 |
0.725 |
|
2006 |
Kwon CH, Luikart BW, Powell CM, Zhou J, Matheny SA, Zhang W, Li Y, Baker SJ, Parada LF. Pten regulates neuronal arborization and social interaction in mice. Neuron. 50: 377-88. PMID 16675393 DOI: 10.1016/J.Neuron.2006.03.023 |
0.736 |
|
2006 |
Kwon CH, Zhou J, Li Y, Kim KW, Hensley LL, Baker SJ, Parada LF. Neuron-specific enolase-cre mouse line with cre activity in specific neuronal populations. Genesis (New York, N.Y. : 2000). 44: 130-5. PMID 16496331 DOI: 10.1002/Gene.20197 |
0.523 |
|
1992 |
Holtzman DM, Li Y, Parada LF, Kinsman S, Chen CK, Valletta JS, Zhou J, Long JB, Mobley WC. p140trk mRNA marks NGF-responsive forebrain neurons: evidence that trk gene expression is induced by NGF. Neuron. 9: 465-78. PMID 1524827 DOI: 10.1016/0896-6273(92)90184-F |
0.5 |
|
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