| Year |
Citation |
Score |
| 2022 |
Moore BD, Levites Y, Xu G, Hampton H, Adamo MF, Croft CL, Futch HS, Moran C, Fromholt S, Janus C, Prokop S, Dickson D, Lewis J, Giasson BI, Golde TE, et al. Soluble brain homogenates from diverse human and mouse sources preferentially seed diffuse Aβ plaque pathology when injected into newborn mouse hosts. Free Neuropathology. 3. PMID 35494163 DOI: 10.17879/freeneuropathology-2022-3766 |
0.373 |
|
| 2019 |
Koller EJ, De La Cruz EG, Machula T, Ibanez KR, Lin WL, Williams T, Riffe CJ, Ryu D, Strang KH, Liu X, Janus C, Golde TE, Dickson D, Giasson BI, Chakrabarty P. Combining P301L and S320F tau variants produces a novel accelerated model of tauopathy. Human Molecular Genetics. PMID 31261380 DOI: 10.1093/Hmg/Ddz151 |
0.457 |
|
| 2018 |
Chakrabarty P, Li A, Ladd TB, Strickland MR, Koller EJ, Burgess JD, Funk CC, Cruz PE, Allen M, Yaroshenko M, Wang X, Younkin C, Reddy J, Lohrer B, Mehrke L, ... ... Janus C, et al. TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease. The Journal of Experimental Medicine. PMID 30158114 DOI: 10.1084/Jem.20180484 |
0.404 |
|
| 2018 |
Giraldo G, Brooks M, Giasson BI, Janus C. Locomotor differences in mice expressing wild-type human α-synuclein. Neurobiology of Aging. 65: 140-148. PMID 29477894 DOI: 10.1016/J.Neurobiolaging.2018.01.020 |
0.371 |
|
| 2017 |
Moore BD, Martin J, de Mena L, Sanchez J, Cruz PE, Ceballos-Diaz C, Ladd TB, Ran Y, Levites Y, Kukar TL, Kurian JJ, McKenna R, Koo EH, Borchelt DR, Janus C, et al. Short Aβ peptides attenuate Aβ42 toxicity in vivo. The Journal of Experimental Medicine. PMID 29208777 DOI: 10.1084/Jem.20170600 |
0.418 |
|
| 2017 |
Eskandari-Sedighi G, Daude N, Gapeshina H, Sanders DW, Kamali-Jamil R, Yang J, Shi B, Wille H, Ghetti B, Diamond MI, Janus C, Westaway D. The CNS in inbred transgenic models of 4-repeat Tauopathy develops consistent tau seeding capacity yet focal and diverse patterns of protein deposition. Molecular Neurodegeneration. 12: 72. PMID 28978354 DOI: 10.1186/S13024-017-0215-7 |
0.368 |
|
| 2016 |
Janus C, Hernandez C, deLelys V, Roder H, Welzl H. Better Utilization of Mouse Models of Neurodegenerative Diseases in Preclinical Studies: From the Bench to the Clinic. Methods in Molecular Biology (Clifton, N.J.). 1438: 311-47. PMID 27150098 DOI: 10.1007/978-1-4939-3661-8_18 |
0.437 |
|
| 2016 |
Moore BD, Martin J, de Mena L, Levites Y, Ceballos-Diaz C, Cruz PE, Janus C, Rincon-Limas DE, Fernandez-Funez P, Golde TE. P1-165: Evidence to Support γ-Secretase Modulators: Short Aβ Peptides are Protective in Vivo Alzheimer's & Dementia. 12: P466-P466. DOI: 10.1016/J.Jalz.2016.06.913 |
0.315 |
|
| 2015 |
Janus C, Flores AY, Xu G, Borchelt DR. Behavioral abnormalities in APPSwe/PS1dE9 mouse model of AD-like pathology: comparative analysis across multiple behavioral domains. Neurobiology of Aging. 36: 2519-32. PMID 26089165 DOI: 10.1016/J.Neurobiolaging.2015.05.010 |
0.412 |
|
| 2015 |
Chakrabarty P, Li A, Ceballos-Diaz C, Eddy JA, Funk CC, Moore B, DiNunno N, Rosario AM, Cruz PE, Verbeeck C, Sacino A, Nix S, Janus C, Price ND, Das P, et al. IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior. Neuron. 85: 519-33. PMID 25619653 DOI: 10.1016/J.Neuron.2014.11.020 |
0.392 |
|
| 2014 |
Janus C, Golde T. The effect of brief neonatal cryoanesthesia on physical development and adult cognitive function in mice. Behavioural Brain Research. 259: 253-60. PMID 24239696 DOI: 10.1016/J.Bbr.2013.11.010 |
0.353 |
|
| 2013 |
Kim J, Chakrabarty P, Hanna A, March A, Dickson DW, Borchelt DR, Golde T, Janus C. Normal cognition in transgenic BRI2-Aβ mice. Molecular Neurodegeneration. 8: 15. PMID 23663320 DOI: 10.1186/1750-1326-8-15 |
0.493 |
|
| 2013 |
Golde TE, Felsenstein K, Chakrabarty P, Li A, Moore B, In JJ, Cruz P, Price A, Borchelt D, Janus C, Cebballos-Diaz C, Rosario A. Harnessing endogenous pathways and metabolites to treat or prevent neurodegenerative disease Molecular Neurodegeneration. 8. DOI: 10.1186/1750-1326-8-S1-O36 |
0.386 |
|
| 2012 |
Hanna A, Iremonger K, Das P, Dickson D, Golde T, Janus C. Age-related increase in amyloid plaque burden is associated with impairment in conditioned fear memory in CRND8 mouse model of amyloidosis. Alzheimer's Research & Therapy. 4: 21. PMID 22697412 DOI: 10.1186/Alzrt124 |
0.443 |
|
| 2012 |
Barten DM, Fanara P, Andorfer C, Hoque N, Wong PY, Husted KH, Cadelina GW, Decarr LB, Yang L, Liu V, Fessler C, Protassio J, Riff T, Turner H, Janus CG, et al. Hyperdynamic microtubules, cognitive deficits, and pathology are improved in tau transgenic mice with low doses of the microtubule-stabilizing agent BMS-241027. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 7137-45. PMID 22623658 DOI: 10.1523/Jneurosci.0188-12.2012 |
0.426 |
|
| 2011 |
Alexander G, Hanna A, Serna V, Younkin L, Younkin S, Janus C. Increased aggression in males in transgenic Tg2576 mouse model of Alzheimer's disease Behavioural Brain Research. 216: 77-83. PMID 20655336 DOI: 10.1016/J.Bbr.2010.07.016 |
0.45 |
|
| 2011 |
Yue M, Hanna A, Wilson J, Roder H, Janus C. Sex difference in pathology and memory decline in rTg4510 mouse model of tauopathy. Neurobiology of Aging. 32: 590-603. PMID 19427061 DOI: 10.1016/J.Neurobiolaging.2009.04.006 |
0.434 |
|
| 2010 |
Melrose HL, Dächsel JC, Behrouz B, Lincoln SJ, Yue M, Hinkle KM, Kent CB, Korvatska E, Taylor JP, Witten L, Liang YQ, Beevers JE, Boules M, Dugger BN, Serna VA, ... ... Janus C, et al. Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice. Neurobiology of Disease. 40: 503-17. PMID 20659558 DOI: 10.1016/J.Nbd.2010.07.010 |
0.394 |
|
| 2010 |
Chakrabarty P, Ceballos-Diaz C, Beccard A, Janus C, Dickson D, Golde TE, Das P. IFN-gamma promotes complement expression and attenuates amyloid plaque deposition in amyloid beta precursor protein transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 184: 5333-43. PMID 20368278 DOI: 10.4049/Jimmunol.0903382 |
0.44 |
|
| 2010 |
Janus C, Welzl H. Mouse models of neurodegenerative diseases: criteria and general methodology. Methods of Molecular Biology. 602: 323-345. PMID 20012407 DOI: 10.1007/978-1-60761-058-8_19 |
0.426 |
|
| 2009 |
Hanna A, Horne P, Yager D, Eckman C, Eckman E, Janus C. Amyloid beta and impairment in multiple memory systems in older transgenic APP TgCRND8 mice. Genes, Brain, and Behavior. 8: 676-84. PMID 19531156 DOI: 10.1111/J.1601-183X.2009.00510.X |
0.458 |
|
| 2007 |
Berger Z, Roder H, Hanna A, Carlson A, Rangachari V, Yue M, Wszolek Z, Ashe K, Knight J, Dickson D, Andorfer C, Rosenberry TL, Lewis J, Hutton M, Janus C. Accumulation of pathological tau species and memory loss in a conditional model of tauopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3650-62. PMID 17409229 DOI: 10.1523/Jneurosci.0587-07.2007 |
0.44 |
|
| 2007 |
Eriksen JL, Janus CG. Plaques, tangles, and memory loss in mouse models of neurodegeneration. Behavior Genetics. 37: 79-100. PMID 17072762 DOI: 10.1007/S10519-006-9118-Z |
0.444 |
|
| 2006 |
Murakami T, Paitel E, Kawarabayashi T, Ikeda M, Chishti MA, Janus C, Matsubara E, Sasaki A, Kawarai T, Phinney AL, Harigaya Y, Horne P, Egashira N, Mishima K, Hanna A, et al. Cortical neuronal and glial pathology in TgTauP301L transgenic mice: neuronal degeneration, memory disturbance, and phenotypic variation. The American Journal of Pathology. 169: 1365-75. PMID 17003492 DOI: 10.2353/Ajpath.2006.051250 |
0.461 |
|
| 2006 |
Maier M, Seabrook TJ, Lazo ND, Jiang L, Das P, Janus C, Lemere CA. Short amyloid-beta (Abeta) immunogens reduce cerebral Abeta load and learning deficits in an Alzheimer's disease mouse model in the absence of an Abeta-specific cellular immune response. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4717-28. PMID 16672644 DOI: 10.1523/Jneurosci.0381-06.2006 |
0.407 |
|
| 2006 |
Futch HS, Kuhn MZ, Levites Y, Moore BD, Janus C, Golde TE. P2-063: A NOVEL IMMUNOTHERAPEUTIC APPROACH TO SIMULTANEOUSLY TARGET BEHAVIORAL STRESS AND DOWNSTREAM PATHOLOGIES IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P690-P691. DOI: 10.1016/J.Jalz.2018.06.748 |
0.321 |
|
| 2006 |
Janus C, Kim J, Hanna A, Wilson J, Price R, Dickson D, Golde T, McGowan E. O4-05-05: Dissociation between amyloid pathology and memory impairment Alzheimer's & Dementia. 2: S85-S86. DOI: 10.1016/J.Jalz.2006.05.331 |
0.341 |
|
| 2006 |
Maier M, Seabrook TJ, Jiang L, Das P, Janus C, Lemere CA. P4-318: Short Aβ immunogens reduce cerebral Aβ load and learning deficits in an APPTG AD mouse model in the absence of an abeta-specific cellular immune response Alzheimer's & Dementia. 2: S610-S610. DOI: 10.1016/J.Jalz.2006.05.2059 |
0.403 |
|
| 2005 |
Meng J, Meng Y, Hanna A, Janus C, Jia Z. Abnormal long-lasting synaptic plasticity and cognition in mice lacking the mental retardation gene Pak3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6641-50. PMID 16014725 DOI: 10.1523/Jneurosci.0028-05.2005 |
0.361 |
|
| 2005 |
Golde TE, Janus C. Homing in on intracellular Abeta? Neuron. 45: 639-42. PMID 15748837 DOI: 10.1016/J.Neuron.2005.02.013 |
0.368 |
|
| 2004 |
Janus C, Welzl H, Hanna A, Lovasic L, Lane N, St George-Hyslop P, Westaway D. Impaired conditioned taste aversion learning in APP transgenic mice. Neurobiology of Aging. 25: 1213-9. PMID 15312967 DOI: 10.1016/J.Neurobiolaging.2003.11.007 |
0.453 |
|
| 2004 |
Janus C. Search strategies used by APP transgenic mice during navigation in the Morris water maze. Learning & Memory. 11: 337-346. PMID 15169864 DOI: 10.1101/Lm.70104 |
0.393 |
|
| 2003 |
Janus C. Vaccines for Alzheimer's disease: how close are we? Cns Drugs. 17: 457-474. PMID 12751917 DOI: 10.2165/00023210-200317070-00001 |
0.424 |
|
| 2002 |
Arawaka S, Hasegawa H, Tandon A, Janus C, Chen F, Yu G, Kikuchi K, Koyama S, Kato T, Fraser PE, St George-Hyslop P. The levels of mature glycosylated nicastrin are regulated and correlate with gamma-secretase processing of amyloid beta-precursor protein. Journal of Neurochemistry. 83: 1065-71. PMID 12437577 DOI: 10.1046/J.1471-4159.2002.01207.X |
0.369 |
|
| 2002 |
McLaurin J, Cecal R, Kierstead ME, Tian X, Phinney AL, Manea M, French JE, Lambermon MH, Darabie AA, Brown ME, Janus C, Chishti MA, Horne P, Westaway D, Fraser PE, et al. Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis. Nature Medicine. 8: 1263-9. PMID 12379850 DOI: 10.1038/Nm790 |
0.437 |
|
| 2001 |
Janus C, Phinney AL, Chishti MA, Westaway D. New developments in animal models of Alzheimer's disease Current Neurology and Neuroscience Reports. 1: 451-457. PMID 11898556 DOI: 10.1007/S11910-001-0105-8 |
0.47 |
|
| 2001 |
Janus C, Westaway D. Transgenic mouse models of Alzheimer's disease. Physiology & Behavior. 73: 873-886. PMID 11566220 DOI: 10.1016/S0031-9384(01)00524-8 |
0.452 |
|
| 2001 |
Chen F, Yu G, Arawaka S, Nishimura M, Kawarai T, Yu H, Tandon A, Supala A, Song YQ, Rogaeva E, Milman P, Sato C, Yu C, Janus C, Lee J, et al. Nicastrin binds to membrane-tethered Notch. Nature Cell Biology. 3: 751-4. PMID 11483961 DOI: 10.1038/35087069 |
0.342 |
|
| 2001 |
Chishti MA, Yang DS, Janus C, Phinney AL, Horne P, Pearson J, Strome R, Zuker N, Loukides J, French J, Turner S, Lozza G, Grilli M, Kunicki S, Morissette C, et al. Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. The Journal of Biological Chemistry. 276: 21562-70. PMID 11279122 DOI: 10.1074/Jbc.M100710200 |
0.5 |
|
| 2000 |
Janus C, Pearson J, McLaurin J, Mathews PM, Jiang Y, Schmidt SD, Chishti MA, Horne P, Heslin D, French J, Mount HT, Nixon RA, Mercken M, Bergeron C, Fraser PE, et al. A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature. 408: 979-82. PMID 11140685 DOI: 10.1038/35050110 |
0.396 |
|
| 2000 |
Yu G, Nishimura M, Arawaka S, Levitan D, Zhang L, Tandon A, Song YQ, Rogaeva E, Chen F, Kawarai T, Supala A, Levesque L, Yu H, Yang DS, Holmes E, ... ... Janus C, et al. Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing. Nature. 407: 48-54. PMID 10993067 DOI: 10.1038/35024009 |
0.321 |
|
| 2000 |
Janus C, D'Amelio S, Amitay O, Chishti MA, Strome R, Fraser P, Carlson GA, Roder JC, St George-Hyslop P, Westaway D. Spatial learning in transgenic mice expressing human presenilin 1 (PS1) transgenes. Neurobiology of Aging. 21: 541-9. PMID 10924767 DOI: 10.1016/S0197-4580(00)00107-X |
0.417 |
|
| 2000 |
Janus C, Chishti MA, Westaway D. Transgenic mouse models of Alzheimer's disease Biochimica Et Biophysica Acta - Molecular Basis of Disease. 1502: 63-75. PMID 10899432 DOI: 10.1016/S0925-4439(00)00033-8 |
0.458 |
|
| 1999 |
Nishimura M, Yu G, Levesque G, Zhang DM, Ruel L, Chen F, Milman P, Holmes E, Liang Y, Kawarai T, Jo E, Supala A, Rogaeva E, Xu DM, Janus C, et al. Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex. Nature Medicine. 5: 164-9. PMID 9930863 DOI: 10.1038/5526 |
0.336 |
|
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