Jan Kehr - Publications

Affiliations: 
Karolinska Institute, Stockholm, Sweden 
Area:
Neuropharmacology

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lietzau G, Magni G, Kehr J, Yoshitake T, Candeias E, Duarte AI, Pettersson H, Skogsberg J, Abbracchio MP, Klein T, Nyström T, Ceruti S, Darsalia V, Patrone C. Dipeptidyl peptidase-4 inhibitors and sulfonylureas prevent the progressive impairment of the nigrostriatal dopaminergic system induced by diabetes during aging. Neurobiology of Aging. PMID 32143981 DOI: 10.1016/j.neurobiolaging.2020.01.004  0.302
2020 Schiffer V, Santiago-Mujika E, Flunkert S, Schmidt S, Farcher M, Loeffler T, Schilcher I, Posch M, Neddens J, Sun Y, Kehr J, Hutter-Paier B. Characterization of the visceral and neuronal phenotype of 4L/PS-NA mice modeling Gaucher disease. Plos One. 15: e0227077. PMID 31929594 DOI: 10.1371/journal.pone.0227077  0.314
2019 Lumsden EW, Troppoli TA, Myers SJ, Zanos P, Aracava Y, Kehr J, Lovett J, Kim S, Wang FH, Schmidt S, Jenne CE, Yuan P, Morris PJ, Thomas CJ, Zarate CA, et al. Antidepressant-relevant concentrations of the ketamine metabolite (2,6)-hydroxynorketamine do not block NMDA receptor function. Proceedings of the National Academy of Sciences of the United States of America. PMID 30796190 DOI: 10.1073/Pnas.1816071116  0.356
2018 Hökfelt T, Barde S, Xu ZD, Kuteeva E, Rüegg J, Le Maitre E, Risling M, Kehr J, Ihnatko R, Theodorsson E, Palkovits M, Deakin W, Bagdy G, Juhasz G, Prud'homme HJ, et al. Neuropeptide and Small Transmitter Coexistence: Fundamental Studies and Relevance to Mental Illness. Frontiers in Neural Circuits. 12: 106. PMID 30627087 DOI: 10.3389/Fncir.2018.00106  0.351
2018 Donello JE, Banerjee P, Li YX, Guo YX, Yoshitake T, Zhang XL, Miry O, Kehr J, Stanton PK, Gross AL, Burgdorf JS, Kroes RA, Moskal JR. Positive N-Methyl-D-Aspartate Receptor Modulation by Rapastinel Promotes Rapid and Sustained Antidepressant-like Effects. The International Journal of Neuropsychopharmacology. PMID 30544218 DOI: 10.1093/Ijnp/Pyy101  0.317
2018 Zhang X, Mantas I, Alvarsson A, Yoshitake T, Shariatgorji M, Pereira M, Nilsson A, Kehr J, Andrén PE, Millan MJ, Chergui K, Svenningsson P. Striatal Tyrosine Hydroxylase Is Stimulated via TAAR1 by 3-Iodothyronamine, But Not by Tyramine or β-Phenylethylamine. Frontiers in Pharmacology. 9: 166. PMID 29545750 DOI: 10.3389/Fphar.2018.00166  0.491
2016 Rivera A, Gago B, Suárez-Boomgaard D, Yoshitake T, Roales-Buján R, Valderrama-Carvajal A, Bilbao A, Medina-Luque J, Díaz-Cabiale Z, Craenenbroeck KV, Borroto-Escuela DO, Kehr J, Rodríguez de Fonseca F, Santín L, de la Calle A, et al. Dopamine D4 receptor stimulation prevents nigrostriatal dopamine pathway activation by morphine: relevance for drug addiction. Addiction Biology. PMID 27212105 DOI: 10.1111/Adb.12407  0.305
2015 Laguna A, Schintu N, Nobre A, Alvarsson A, Volakakis N, Jacobsen JK, Gómez-Galán M, Sopova E, Joodmardi E, Yoshitake T, Deng Q, Kehr J, Ericson J, Svenningsson P, Shupliakov O, et al. Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease. Nature Neuroscience. 18: 826-35. PMID 25915474 DOI: 10.1038/nn.4004  0.483
2015 Ádori C, Glück L, Barde S, Yoshitake T, Kovacs GG, Mulder J, Maglóczky Z, Havas L, Bölcskei K, Mitsios N, Uhlén M, Szolcsányi J, Kehr J, Rönnbäck A, Schwartz T, et al. Critical role of somatostatin receptor 2 in the vulnerability of the central noradrenergic system: new aspects on Alzheimer's disease. Acta Neuropathologica. 129: 541-63. PMID 25676386 DOI: 10.1007/S00401-015-1394-3  0.328
2014 Yoshitake S, Kuteeva E, Hökfelt T, Mennicken F, Theodorsson E, Yamaguchi M, Kehr J, Yoshitake T. Correlation between the effects of local and intracerebroventricular infusions of galanin on 5-HT release studied by microdialysis, and distribution of galanin and galanin receptors in prefrontal cortex, ventral hippocampus, amygdala, hypothalamus, and striatum of awake rats. Synapse (New York, N.Y.). 68: 179-93. PMID 24430888 DOI: 10.1002/syn.21730  0.322
2013 Kadkhodaei B, Alvarsson A, Schintu N, Ramsköld D, Volakakis N, Joodmardi E, Yoshitake T, Kehr J, Decressac M, Björklund A, Sandberg R, Svenningsson P, Perlmann T. Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons. Proceedings of the National Academy of Sciences of the United States of America. 110: 2360-5. PMID 23341612 DOI: 10.1073/Pnas.1221077110  0.483
2013 Eriksson TM, Alvarsson A, Stan TL, Zhang X, Hascup KN, Hascup ER, Kehr J, Gerhardt GA, Warner-Schmidt J, Arango-Lievano M, Kaplitt MG, Ogren SO, Greengard P, Svenningsson P. Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11. Molecular Psychiatry. 18: 1096-105. PMID 23032875 DOI: 10.1038/Mp.2012.130  0.717
2012 Machaczka M, Arce MP, Rucinska M, Yoshitake T, Kehr J, Jurczak W, Skotnicki AB, Månsson JE, Tylki-Szymanska A, Svenningsson P. A twelve-year follow-up study on a case of early-onset parkinsonism preceding clinical manifestation of Gaucher disease. Jimd Reports. 3: 53-7. PMID 23430873 DOI: 10.1007/8904_2011_48  0.4
2012 Hascup ER, Hascup KN, Pomerleau F, Huettl P, Hajos-Korcsok E, Kehr J, Gerhardt GA. An allosteric modulator of metabotropic glutamate receptors (mGluRâ‚‚), (+)-TFMPIP, inhibits restraint stress-induced phasic glutamate release in rat prefrontal cortex. Journal of Neurochemistry. 122: 619-27. PMID 22578190 DOI: 10.1111/j.1471-4159.2012.07784.x  0.747
2012 Marcellino D, Kehr J, Agnati LF, Fuxe K. Increased affinity of dopamine for D(2) -like versus D(1) -like receptors. Relevance for volume transmission in interpreting PET findings. Synapse (New York, N.Y.). 66: 196-203. PMID 22034017 DOI: 10.1002/syn.21501  0.301
2011 Savage S, Kehr J, Olson L, Mattsson A. Impaired social interaction and enhanced sensitivity to phencyclidine-induced deficits in novel object recognition in rats with cortical cholinergic denervation. Neuroscience. 195: 60-9. PMID 21875653 DOI: 10.1016/j.neuroscience.2011.08.027  0.313
2011 Hascup KN, Hascup ER, Stephens ML, Glaser PE, Yoshitake T, Mathé AA, Gerhardt GA, Kehr J. Resting glutamate levels and rapid glutamate transients in the prefrontal cortex of the Flinders Sensitive Line rat: a genetic rodent model of depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1769-77. PMID 21525860 DOI: 10.1038/Npp.2011.60  0.743
2010 Kehr J, Hu XJ, Yoshitake T, Wang FH, Osborne P, Stenfors C, Ogren SO. The selective 5-HT(1A) receptor antagonist NAD-299 increases acetylcholine release but not extracellular glutamate levels in the frontal cortex and hippocampus of awake rat. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 20: 487-500. PMID 20413275 DOI: 10.1016/j.euroneuro.2010.03.003  0.392
2010 Marcellino D, Suárez-Boomgaard D, Sánchez-Reina MD, Aguirre JA, Yoshitake T, Yoshitake S, Hagman B, Kehr J, Agnati LF, Fuxe K, Rivera A. On the role of P2X(7) receptors in dopamine nerve cell degeneration in a rat model of Parkinson's disease: studies with the P2X(7) receptor antagonist A-438079. Journal of Neural Transmission (Vienna, Austria : 1996). 117: 681-7. PMID 20387084 DOI: 10.1007/s00702-010-0400-0  0.331
2010 Nikisch G, Baumann P, Kiessling B, Reinert M, Wiedemann G, Kehr J, Mathé AA, Piel M, Roesch F, Weisser H, Schneider P, Hertel A. Relationship between dopamine D2 receptor occupancy, clinical response, and drug and monoamine metabolites levels in plasma and cerebrospinal fluid. A pilot study in patients suffering from first-episode schizophrenia treated with quetiapine. Journal of Psychiatric Research. 44: 754-9. PMID 20176367 DOI: 10.1016/j.jpsychires.2010.02.004  0.314
2010 Galter D, Pernold K, Yoshitake T, Lindqvist E, Hoffer B, Kehr J, Larsson NG, Olson L. MitoPark mice mirror the slow progression of key symptoms and L-DOPA response in Parkinson's disease. Genes, Brain, and Behavior. 9: 173-81. PMID 20002202 DOI: 10.1111/j.1601-183X.2009.00542.x  0.322
2009 Ögren S, Eriksson T, Kehr J, Svenningsson P, Stiedl O. S.2.03 The role of 5-HT1A receptors in emotional memory: implications for anxiety and depression European Neuropsychopharmacology. 19: S115-S116. DOI: 10.1016/S0924-977X(09)70125-7  0.471
2009 Hascup K, Hascup E, Gerhardt G, Mathé A, Kehr J. P.2.10 Neuropeptide Y modulation of the gluta-matergic system in the Flinders Sensitive Line rat: a rat model of depression European Neuropsychopharmacology. 19: S41-S42. DOI: 10.1016/S0924-977X(09)70048-3  0.744
2009 Hascup E, Hascup K, Pomerleau F, Huettl P, Gerhardt G, Kehr J. P.2.09 The source of resting and physiologically-evoked L-glutamate levels in prefrontal cortex in awake rats European Neuropsychopharmacology. 19: S40-S41. DOI: 10.1016/S0924-977X(09)70047-1  0.748
2008 Ogren SO, Eriksson TM, Elvander-Tottie E, D'Addario C, Ekström JC, Svenningsson P, Meister B, Kehr J, Stiedl O. The role of 5-HT(1A) receptors in learning and memory. Behavioural Brain Research. 195: 54-77. PMID 18394726 DOI: 10.1016/j.bbr.2008.02.023  0.471
2007 Fuxe K, Dahlström A, Höistad M, Marcellino D, Jansson A, Rivera A, Diaz-Cabiale Z, Jacobsen K, Tinner-Staines B, Hagman B, Leo G, Staines W, Guidolin D, Kehr J, Genedani S, et al. From the Golgi-Cajal mapping to the transmitter-based characterization of the neuronal networks leading to two modes of brain communication: wiring and volume transmission. Brain Research Reviews. 55: 17-54. PMID 17433836 DOI: 10.1016/J.Brainresrev.2007.02.009  0.321
2007 Hu XJ, Wang FH, Stenfors C, Ogren SO, Kehr J. Effects of the 5-HT1B receptor antagonist NAS-181 on extracellular levels of acetylcholine, glutamate and GABA in the frontal cortex and ventral hippocampus of awake rats: a microdialysis study. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 17: 580-6. PMID 17234388 DOI: 10.1016/j.euroneuro.2006.12.002  0.38
2006 Ogren SO, Kuteeva E, Hökfelt T, Kehr J. Galanin receptor antagonists : a potential novel pharmacological treatment for mood disorders. Cns Drugs. 20: 633-54. PMID 16863269 DOI: 10.2165/00023210-200620080-00003  0.359
2005 Aguirre JA, Kehr J, Yoshitake T, Liu FL, Rivera A, Fernandez-Espinola S, Andbjer B, Leo G, Medhurst AD, Agnati LF, Fuxe K. Protection but maintained dysfunction of nigral dopaminergic nerve cell bodies and striatal dopaminergic terminals in MPTP-lesioned mice after acute treatment with the mGluR5 antagonist MPEP. Brain Research. 1033: 216-20. PMID 15694927 DOI: 10.1016/j.brainres.2004.11.040  0.324
2004 Tanganelli S, Sandager Nielsen K, Ferraro L, Antonelli T, Kehr J, Franco R, Ferré S, Agnati LF, Fuxe K, Scheel-Krüger J. Striatal plasticity at the network level. Focus on adenosine A2A and D2 interactions in models of Parkinson's Disease. Parkinsonism & Related Disorders. 10: 273-80. PMID 15196505 DOI: 10.1016/j.parkreldis.2004.02.015  0.306
2004 Yoshitake T, Wang FH, Kuteeva E, Holmberg K, Yamaguchi M, Crawley JN, Steiner R, Bartfai T, Ogren SO, Hökfelt T, Kehr J. Enhanced hippocampal noradrenaline and serotonin release in galanin-overexpressing mice after repeated forced swimming test. Proceedings of the National Academy of Sciences of the United States of America. 101: 354-9. PMID 14701907 DOI: 10.1073/pnas.0307042101  0.331
2003 Yoshitake T, Yamaguchi M, Nohta H, Ichinose F, Yoshida H, Yoshitake S, Fuxe K, Kehr J. Determination of histamine in microdialysis samples from rat brain by microbore column liquid chromatography following intramolecular excimer-forming derivatization with pyrene-labeling reagent. Journal of Neuroscience Methods. 127: 11-7. PMID 12865144 DOI: 10.1016/S0165-0270(03)00097-9  0.318
2003 Yoshitake T, Reenilä I, Ogren SO, Hökfelt T, Kehr J. Galanin attenuates basal and antidepressant drug-induced increase of extracellular serotonin and noradrenaline levels in the rat hippocampus. Neuroscience Letters. 339: 239-42. PMID 12633897 DOI: 10.1016/S0304-3940(03)00020-X  0.343
2001 Kehr J, Yoshitake T, Wang FH, Wynick D, Holmberg K, Lendahl U, Bartfai T, Yamaguchi M, Hökfelt T, Ogren SO. Microdialysis in freely moving mice: determination of acetylcholine, serotonin and noradrenaline release in galanin transgenic mice. Journal of Neuroscience Methods. 109: 71-80. PMID 11489302 DOI: 10.1016/S0165-0270(01)00403-4  0.319
2000 Strömberg I, Kehr J, Fuxe K. Restoration of dopamine transmission in graft reinnervated striatum. Evidence for regulation of dopamine D2 receptor function in regions lacking dopamine. Progress in Brain Research. 125: 309-15. PMID 11098667 DOI: 10.1016/S0079-6123(00)25020-6  0.306
2000 Kehr J, Höistad M, Fuxe K. Diffusion of radiolabeled dopamine, its metabolites and mannitol in the rat striatum studied by dual-probe microdialysis. Progress in Brain Research. 125: 179-90. PMID 11098656 DOI: 10.1016/S0079-6123(00)25009-7  0.317
2000 O'Meara G, Coumis U, Ma SY, Kehr J, Mahoney S, Bacon A, Allen SJ, Holmes F, Kahl U, Wang FH, Kearns IR, Ove-Ogren S, Dawbarn D, Mufson EJ, Davies C, et al. Galanin regulates the postnatal survival of a subset of basal forebrain cholinergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 97: 11569-74. PMID 11016971 DOI: 10.1073/Pnas.210254597  0.317
2000 Höistad M, Kehr J, Andbjer B, Jansson A, Fuxe K. Intracerebral infusion of H-dopamine and H-mannitol in the striatum of halothane-anaesthetized male rats. A dual-probe microdialysis study of long-distance diffusion. The European Journal of Neuroscience. 12: 2505-14. PMID 10947826 DOI: 10.1046/j.1460-9568.2000.00141.x  0.303
2000 Strömberg I, Kehr J, Andbjer B, Fuxe K. Fetal ventral mesencephalic grafts functionally reduce the dopamine D2 receptor supersensitivity in partially dopamine reinnervated host striatum. Experimental Neurology. 164: 154-65. PMID 10877926 DOI: 10.1006/exnr.2000.7421  0.334
1996 You ZB, Herrera-Marschitz M, Nylander I, Goiny M, Kehr J, Ungerstedt U, Terenius L. Effect of morphine on dynorphin B and GABA release in the basal ganglia of rats. Brain Research. 710: 241-8. PMID 8963665 DOI: 10.1016/0006-8993(95)01402-0  0.331
1996 You ZB, Herrera-Marschitz M, Pettersson E, Nylander I, Goiny M, Shou HZ, Kehr J, Godukhin O, Hökfelt T, Terenius L, Ungerstedt U. Modulation of neurotransmitter release by cholecystokinin in the neostriatum and substantia nigra of the rat: regional and receptor specificity. Neuroscience. 74: 793-804. PMID 8884775 DOI: 10.1016/0306-4522(96)00149-2  0.368
1991 Osborne PG, O'Connor WT, Kehr J, Ungerstedt U. In vivo characterisation of extracellular dopamine, GABA and acetylcholine from the dorsolateral striatum of awake freely moving rats by chronic microdialysis. Journal of Neuroscience Methods. 37: 93-102. PMID 1679148 DOI: 10.1016/0165-0270(91)90119-K  0.32
1990 Drew KL, O'Connor WT, Kehr J, Ungerstedt U. Regional specific effects of clozapine and haloperidol on GABA and dopamine release in rat basal ganglia. European Journal of Pharmacology. 187: 385-97. PMID 2073921 DOI: 10.1016/0014-2999(90)90366-E  0.319
1990 Reid MS, Herrera-Marschitz M, Kehr J, Ungerstedt U. Striatal dopamine and glutamate release: effects of intranigral injections of substance P. Acta Physiologica Scandinavica. 140: 527-37. PMID 1707211 DOI: 10.1111/j.1748-1716.1990.tb09030.x  0.366
Show low-probability matches.