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Michael G. Kaplitt, MD/PhD - Publications

Affiliations: 
Neurological Surgery New York Presbyterian/Weill Cornell 
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107 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Stavarache MA, Chazen JL, Kaplitt MG. Innovative Applications of MR-Guided Focused Ultrasound for Neurological Disorders. World Neurosurgery. 145: 581-589. PMID 33348524 DOI: 10.1016/j.wneu.2020.08.052  0.76
2021 Stavarache MA, Chazen JL, Kaplitt MG. Foundations of Magnetic Resonance-Guided Focused Ultrasonography. World Neurosurgery. 145: 567-573. PMID 33348522 DOI: 10.1016/j.wneu.2020.08.051  0.76
2018 Stavarache MA, Petersen N, Jurgens EM, Milstein ER, Rosenfeld ZB, Ballon DJ, Kaplitt MG. Safe and stable noninvasive focal gene delivery to the mammalian brain following focused ultrasound. Journal of Neurosurgery. 1-10. PMID 29701544 DOI: 10.3171/2017.8.JNS17790  0.76
2017 Kelm-Nelson CA, Brauer AFL, Barth KJ, Lake JM, Sinnen MLK, Stehula FJ, Muslu C, Marongiu R, Kaplitt MG, Ciucci MR. Characterization of early-onset motor deficits in the Pink1 -/- mouse model of Parkinson disease. Brain Research. PMID 29229503 DOI: 10.1016/j.brainres.2017.12.002  0.68
2017 Chazen JL, Sarva H, Stieg PE, Min RJ, Ballon DJ, Pryor KO, Riegelhaupt PM, Kaplitt MG. Clinical improvement associated with targeted interruption of the cerebellothalamic tract following MR-guided focused ultrasound for essential tremor. Journal of Neurosurgery. 1-9. PMID 29053074 DOI: 10.3171/2017.4.JNS162803  0.76
2016 Marongiu R, Arango-Lievano M, Francardo V, Morgenstern P, Zhang X, Cenci MA, Svenningsson P, Greengard P, Kaplitt MG. Gene therapy blockade of dorsal striatal p11 improves motor function and dyskinesia in parkinsonian mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787858 DOI: 10.1073/pnas.1524387113  0.68
2016 Schintu N, Zhang X, Alvarsson A, Marongiu R, Kaplitt MG, Greengard P, Svenningsson P. p11 modulates L-DOPA therapeutic effects and dyskinesia via distinct cell types in experimental Parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787846 DOI: 10.1073/pnas.1524303113  0.68
2016 Virk MS, Sagi Y, Medrihan L, Leung J, Kaplitt MG, Greengard P. Opposing roles for serotonin in cholinergic neurons of the ventral and dorsal striatum. Proceedings of the National Academy of Sciences of the United States of America. PMID 26733685 DOI: 10.1073/pnas.1524183113  0.68
2015 Stavarache MA, Musatov S, McGill M, Vernov M, Kaplitt MG. The tumor suppressor PTEN regulates motor responses to striatal dopamine in normal and Parkinsonian animals. Neurobiology of Disease. 82: 487-494. PMID 26232589 DOI: 10.1016/j.nbd.2015.07.013  0.68
2015 Arango-Lievano M, Kaplitt MG. [Depression and addiction comorbidity: towards a common molecular target?]. MéDecine Sciences : M/S. 31: 546-50. PMID 26059306 DOI: 10.1051/medsci/20153105017  0.68
2015 Salgado S, Kaplitt MG. The Nucleus Accumbens: A Comprehensive Review. Stereotactic and Functional Neurosurgery. 93: 75-93. PMID 25720819 DOI: 10.1159/000368279  0.68
2015 Gürsel DB, Banu MA, Berry N, Marongiu R, Burkhardt JK, Kobylarz K, Kaplitt MG, Rafii S, Boockvar JA. Tight regulation between cell survival and programmed cell death in GBM stem-like cells by EGFR/GSK3b/PP2A signaling. Journal of Neuro-Oncology. 121: 19-29. PMID 25344882 DOI: 10.1007/s11060-014-1602-3  0.68
2014 Sagi Y, Heiman M, Peterson JD, Musatov S, Scarduzio M, Logan SM, Kaplitt MG, Surmeier DJ, Heintz N, Greengard P. Nitric oxide regulates synaptic transmission between spiny projection neurons. Proceedings of the National Academy of Sciences of the United States of America. 111: 17636-41. PMID 25413364 DOI: 10.1073/pnas.1420162111  0.68
2014 Kovanlikaya I, Heier L, Kaplitt M. Treatment of chronic pain: Diffusion tensor imaging identification of the ventroposterolateral nucleus confirmed with successful deep brain stimulation Stereotactic and Functional Neurosurgery. 92: 365-371. PMID 25359091 DOI: 10.1159/000366002  0.68
2014 Ko JH, Feigin A, Mattis PJ, Tang CC, Ma Y, Dhawan V, During MJ, Kaplitt MG, Eidelberg D. Network modulation following sham surgery in Parkinson's disease. The Journal of Clinical Investigation. 124: 3656-66. PMID 25036712 DOI: 10.1172/JCI75073  0.68
2014 Plotkin JL, Day M, Peterson JD, Xie Z, Kress GJ, Rafalovich I, Kondapalli J, Gertler TS, Flajolet M, Greengard P, Stavarache M, Kaplitt MG, Rosinski J, Chan CS, Surmeier DJ. Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington's disease. Neuron. 83: 178-88. PMID 24991961 DOI: 10.1016/j.neuron.2014.05.032  0.68
2014 Arango-Lievano M, Schwarz JT, Vernov M, Wilkinson MB, Bradbury K, Feliz A, Marongiu R, Gelfand Y, Warner-Schmidt J, Nestler EJ, Greengard P, Russo SJ, Kaplitt MG. Cell-type specific expression of p11 controls cocaine reward. Biological Psychiatry. 76: 794-801. PMID 24725970 DOI: 10.1016/j.biopsych.2014.02.012  0.68
2014 Nuttin B, Wu H, Mayberg H, Hariz M, Gabriëls L, Galert T, Merkel R, Kubu C, Vilela-Filho O, Matthews K, Taira T, Lozano AM, Schechtmann G, Doshi P, Broggi G, ... ... Kaplitt M, et al. Consensus on guidelines for stereotactic neurosurgery for psychiatric disorders. Journal of Neurology, Neurosurgery, and Psychiatry. 85: 1003-8. PMID 24444853 DOI: 10.1136/jnnp-2013-306580  0.68
2014 Haws ME, Jaramillo TC, Espinosa F, Widman AJ, Stuber GD, Sparta DR, Tye KM, Russo SJ, Parada LF, Stavarache M, Kaplitt M, Bonci A, Powell CM. PTEN knockdown alters dendritic spine/protrusion morphology, not density. The Journal of Comparative Neurology. 522: 1171-90. PMID 24264880 DOI: 10.1002/cne.23488  0.68
2013 Orlin A, Sondhi D, Witmer MT, Wessel MM, Mezey JG, Kaminsky SM, Hackett NR, Yohay K, Kosofsky B, Souweidane MM, Kaplitt MG, D'Amico DJ, Crystal RG, Kiss S. Spectrum of ocular manifestations in CLN2-associated batten (Jansky-Bielschowsky) disease correlate with advancing age and deteriorating neurological function. Plos One. 8: e73128. PMID 24015292 DOI: 10.1371/journal.pone.0073128  0.68
2013 Kaplitt MG. Spinal cord stimulation for vegetative state: is this ready for prime time? Stereotactic and Functional Neurosurgery. 91: 288-9. PMID 23797317 DOI: 10.1159/000348272  0.68
2013 Liu T, Eskreis-Winkler S, Schweitzer AD, Chen W, Kaplitt MG, Tsiouris AJ, Wang Y. Improved subthalamic nucleus depiction with quantitative susceptibility mapping. Radiology. 269: 216-23. PMID 23674786 DOI: 10.1148/radiol.13121991  0.68
2013 Malhotra VT, Root J, Kesselbrenner J, Njoku I, Cubert K, Gulati A, Puttanniah V, Bilsky M, Kaplitt M. Intrathecal pain pump infusions for intractable cancer pain: an algorithm for dosing without a neuraxial trial. Anesthesia and Analgesia. 116: 1364-70. PMID 23558833 DOI: 10.1213/ANE.0b013e31828d670e  0.68
2013 Gelfand Y, Kaplitt MG. Gene therapy for psychiatric disorders. World Neurosurgery. 80: S32.e11-8. PMID 23268195 DOI: 10.1016/j.wneu.2012.12.028  0.68
2013 Dyke JP, Sondhi D, Voss HU, Shungu DC, Mao X, Yohay K, Worgall S, Hackett NR, Hollmann C, Yeotsas ME, Jeong AL, Van de Graaf B, Cao I, Kaminsky SM, Heier LA, ... ... Kaplitt MG, et al. Assessment of disease severity in late infantile neuronal ceroid lipofuscinosis using multiparametric MR imaging. Ajnr. American Journal of Neuroradiology. 34: 884-9. PMID 23042927 DOI: 10.3174/ajnr.A3297  0.68
2013 Eriksson TM, Alvarsson A, Stan TL, Zhang X, Hascup KN, Hascup ER, Kehr J, Gerhardt GA, Warner-Schmidt J, Arango-Lievano M, Kaplitt MG, Ogren SO, Greengard P, Svenningsson P. Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11. Molecular Psychiatry. 18: 1096-105. PMID 23032875 DOI: 10.1038/mp.2012.130  0.68
2012 Sondhi D, Johnson L, Purpura K, Monette S, Souweidane MM, Kaplitt MG, Kosofsky B, Yohay K, Ballon D, Dyke J, Kaminksy SM, Hackett NR, Crystal RG. Long-term expression and safety of administration of AAVrh.10hCLN2 to the brain of rats and nonhuman primates for the treatment of late infantile neuronal ceroid lipofuscinosis. Human Gene Therapy Methods. 23: 324-35. PMID 23131032 DOI: 10.1089/hgtb.2012.120  0.68
2012 Warner-Schmidt JL, Schmidt EF, Marshall JJ, Rubin AJ, Arango-Lievano M, Kaplitt MG, Ibañez-Tallon I, Heintz N, Greengard P. Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior. Proceedings of the National Academy of Sciences of the United States of America. 109: 11360-5. PMID 22733786 DOI: 10.1073/pnas.1209293109  0.68
2012 Mure H, Tang CC, Argyelan M, Ghilardi MF, Kaplitt MG, Dhawan V, Eidelberg D. Improved sequence learning with subthalamic nucleus deep brain stimulation: evidence for treatment-specific network modulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 2804-13. PMID 22357863 DOI: 10.1523/JNEUROSCI.4331-11.2012  0.68
2012 Nanaszko MJ, Kaplitt MG. Molecular Therapies for Movement Disorders Schmidek and Sweet Operative Neurosurgical Techniques: Indications, Methods, and Results: Sixth Edition. 2: 1337-1345. DOI: 10.1016/B978-1-4160-6839-6.10117-0  0.68
2011 Morgenstern PF, Marongiu R, Musatov SA, Kaplitt MG. Adeno-associated viral gene delivery in neurodegenerative disease. Methods in Molecular Biology (Clifton, N.J.). 793: 443-55. PMID 21913118 DOI: 10.1007/978-1-61779-328-8_29  0.68
2011 LeWitt PA, Rezai AR, Leehey MA, Ojemann SG, Flaherty AW, Eskandar EN, Kostyk SK, Thomas K, Sarkar A, Siddiqui MS, Tatter SB, Schwalb JM, Poston KL, Henderson JM, Kurlan RM, ... ... Kaplitt MG, et al. AAV2-GAD gene therapy for advanced Parkinson's disease: a double-blind, sham-surgery controlled, randomised trial. The Lancet. Neurology. 10: 309-19. PMID 21419704 DOI: 10.1016/S1474-4422(11)70039-4  0.68
2011 Gürsel DB, Beyene RT, Hofstetter C, Greenfield JP, Souweidane MM, Kaplitt M, Arango-Lievano M, Howard B, Boockvar JA. Optimization of glioblastoma multiforme stem cell isolation, transfection, and transduction Journal of Neuro-Oncology. 104: 509-522. PMID 21336775 DOI: 10.1007/s11060-011-0528-2  0.68
2011 Katzen H, Ravdin LD, Assuras S, Heros R, Kaplitt M, Schwartz TH, Fink M, Levin BE, Relkin NR. Postshunt cognitive and functional improvement in idiopathic normal pressure hydrocephalus. Neurosurgery. 68: 416-9. PMID 21135747 DOI: 10.1227/NEU.0b013e3181ff9d01  0.68
2010 Alexander B, Warner-Schmidt J, Eriksson T, Tamminga C, Arango-Lievano M, Arango-Llievano M, Ghose S, Vernov M, Stavarache M, Stavarche M, Musatov S, Flajolet M, Svenningsson P, Greengard P, Kaplitt MG. Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens. Science Translational Medicine. 2: 54ra76. PMID 20962330 DOI: 10.1126/scitranslmed.3001079  0.68
2010 Souweidane MM, Fraser JF, Arkin LM, Sondhi D, Hackett NR, Kaminsky SM, Heier L, Kosofsky BE, Worgall S, Crystal RG, Kaplitt MG. Gene therapy for late infantile neuronal ceroid lipofuscinosis: neurosurgical considerations. Journal of Neurosurgery. Pediatrics. 6: 115-22. PMID 20672930 DOI: 10.3171/2010.4.PEDS09507  0.68
2010 Fisher R, Salanova V, Witt T, Worth R, Henry T, Gross R, Oommen K, Osorio I, Nazzaro J, Labar D, Kaplitt M, Sperling M, Sandok E, Neal J, Handforth A, et al. Electrical stimulation of the anterior nucleus of thalamus for treatment of refractory epilepsy. Epilepsia. 51: 899-908. PMID 20331461 DOI: 10.1111/j.1528-1167.2010.02536.x  0.68
2010 Kaplitt MG. Parkinson disease: Another player in gene therapy for Parkinson disease. Nature Reviews. Neurology. 6: 7-8. PMID 20057491 DOI: 10.1038/nrneurol.2009.214  0.68
2010 Alexander B, Warner-Schmidt J, Eriksson T, Tamminga C, Arango-Lievano M, Ghose S, Vernov M, Stavarache M, Musatov S, Flajolet M, Svenningsson P, Greengard P, Kaplitt MG. Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens (Science Translational Medicine (2010) 2, (62er4)) Science Translational Medicine. 2. DOI: 10.1126/scitranslmed.3001996  0.68
2010 Alexander B, Warner-Schmidt J, Eriksson T, Tamminga C, Arango-Llievano M, Ghose S, Vernov M, Stavarche M, Musatov S, Flajolet M, Svenningsson P, Greengard P, Kaplitt MG. Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens (Science Translational Medicine (2010) 2, (55er3)) Science Translational Medicine. 2. DOI: 10.1126/scitranslmed.3001841  0.68
2009 Johnson F, Kaplitt MG. Novel mitochondrial substrates of omi indicate a new regulatory role in neurodegenerative disorders. Plos One. 4: e7100. PMID 19763263 DOI: 10.1371/journal.pone.0007100  0.68
2009 Kaplitt MG. Gene therapy clinical trials in the human brain. Protocol development and review of current applications. Frontiers of Neurology and Neuroscience. 25: 180-8. PMID 19478520 DOI: 10.1159/000209498  0.68
2009 Kaplitt MG, Barbaro N. Clinical trials of surgical devices for neurological disorders. Frontiers of Neurology and Neuroscience. 25: 174-9. PMID 19478519 DOI: 10.1159/000209497  0.68
2009 Pourfar M, Tang C, Lin T, Dhawan V, Kaplitt MG, Eidelberg D. Assessing the microlesion effect of subthalamic deep brain stimulation surgery with FDG PET. Journal of Neurosurgery. 110: 1278-82. PMID 19301972 DOI: 10.3171/2008.12.JNS08991  0.68
2009 Liu W, Vives-Bauza C, Acín-Peréz- R, Yamamoto A, Tan Y, Li Y, Magrané J, Stavarache MA, Shaffer S, Chang S, Kaplitt MG, Huang XY, Beal MF, Manfredi G, Li C. PINK1 defect causes mitochondrial dysfunction, proteasomal deficit and alpha-synuclein aggregation in cell culture models of Parkinson's disease. Plos One. 4: e4597. PMID 19242547 DOI: 10.1371/journal.pone.0004597  0.76
2009 Schultz KN, von Esenwein SA, Hu M, Bennett AL, Kennedy RT, Musatov S, Toran-Allerand CD, Kaplitt MG, Young LJ, Becker JB. Viral vector-mediated overexpression of estrogen receptor-alpha in striatum enhances the estradiol-induced motor activity in female rats and estradiol-modulated GABA release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1897-903. PMID 19211896 DOI: 10.1523/JNEUROSCI.4647-08.2009  0.68
2008 Worgall S, Sondhi D, Hackett NR, Kosofsky B, Kekatpure MV, Neyzi N, Dyke JP, Ballon D, Heier L, Greenwald BM, Christos P, Mazumdar M, Souweidane MM, Kaplitt MG, Crystal RG. Treatment of late infantile neuronal ceroid lipofuscinosis by CNS administration of a serotype 2 adeno-associated virus expressing CLN2 cDNA. Human Gene Therapy. 19: 463-74. PMID 18473686 DOI: 10.1089/hum.2008.022  0.68
2008 Kaplitt MG. Comments Neurosurgery. 62: 862. DOI: 10.1227/01.neu.0000318171.82719.35  0.68
2007 Feigin A, Kaplitt MG, Tang C, Lin T, Mattis P, Dhawan V, During MJ, Eidelberg D. Modulation of metabolic brain networks after subthalamic gene therapy for Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 104: 19559-64. PMID 18042721 DOI: 10.1073/pnas.0706006104  0.68
2007 Worgall S, Kekatpure MV, Heier L, Ballon D, Dyke JP, Shungu D, Mao X, Kosofsky B, Kaplitt MG, Souweidane MM, Sondhi D, Hackett NR, Hollmann C, Crystal RG. Neurological deterioration in late infantile neuronal ceroid lipofuscinosis. Neurology. 69: 521-35. PMID 17679671 DOI: 10.1212/01.wnl.0000267885.47092.40  0.68
2007 Kaplitt MG, Feigin A, Tang C, Fitzsimons HL, Mattis P, Lawlor PA, Bland RJ, Young D, Strybing K, Eidelberg D, During MJ. Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial. Lancet. 369: 2097-105. PMID 17586305 DOI: 10.1016/S0140-6736(07)60982-9  0.68
2007 Musatov S, Chen W, Pfaff DW, Mobbs CV, Yang XJ, Clegg DJ, Kaplitt MG, Ogawa S. Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome. Proceedings of the National Academy of Sciences of the United States of America. 104: 2501-6. PMID 17284595 DOI: 10.1073/pnas.0610787104  0.32
2007 Chan DK, Lieberman DM, Musatov S, Goldfein JA, Selesnick SH, Kaplitt MG. Protection against cisplatin-induced ototoxicity by adeno-associated virus-mediated delivery of the X-linked inhibitor of apoptosis protein is not dependent on caspase inhibition. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 28: 417-25. PMID 17211286 DOI: 10.1097/01.mao.0000247826.28893.7a  0.68
2007 Emborg ME, Carbon M, Holden JE, During MJ, Ma Y, Tang C, Moirano J, Fitzsimons H, Roitberg BZ, Tuccar E, Roberts A, Kaplitt MG, Eidelberg D. Subthalamic glutamic acid decarboxylase gene therapy: changes in motor function and cortical metabolism. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 501-9. PMID 16835631 DOI: 10.1038/sj.jcbfm.9600364  0.68
2007 Kaplitt MG. Commentary Surgical Neurology. 67: 20. DOI: 10.1016/j.surneu.2006.08.007  0.68
2006 Asanuma K, Tang C, Ma Y, Dhawan V, Mattis P, Edwards C, Kaplitt MG, Feigin A, Eidelberg D. Network modulation in the treatment of Parkinson's disease. Brain : a Journal of Neurology. 129: 2667-78. PMID 16844713 DOI: 10.1093/brain/awl162  0.68
2006 Betchen SA, Musatov S, Roberts J, Pena J, Kaplitt MG. PTEN inhibits adrenomedullin expression and function in brain tumor cells. Journal of Neuro-Oncology. 79: 117-23. PMID 16821090 DOI: 10.1007/s11060-005-9035-7  0.68
2006 Musatov S, Chen W, Pfaff DW, Kaplitt MG, Ogawa S. RNAi-mediated silencing of estrogen receptor {alpha} in the ventromedial nucleus of hypothalamus abolishes female sexual behaviors. Proceedings of the National Academy of Sciences of the United States of America. 103: 10456-60. PMID 16803960 DOI: 10.1073/pnas.0603045103  0.32
2006 Cooper LB, Chan DK, Roediger FC, Shaffer BR, Fraser JF, Musatov S, Selesnick SH, Kaplitt MG. AAV-mediated delivery of the caspase inhibitor XIAP protects against cisplatin ototoxicity. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 27: 484-90. PMID 16791039 DOI: 10.1097/01.mao.0000202647.19355.6a  0.68
2006 Sondhi D, Hackett NR, Kaminsky SM, Souweidane MM, Kaplitt MG, Crystal RG. Gene Therapy for the Late Infantile Form of Batten Disease Gene Therapy of the Central Nervous System: From Bench to Bedside. 317-333. DOI: 10.1016/B978-012397632-1/50025-3  0.68
2006 Musatov S, Kaplitt MG, Pfaff DW, Ogawa S. Use of Viral Vectors to Influence Behavior Gene Therapy of the Central Nervous System: From Bench to Bedside. 195-205. DOI: 10.1016/B978-012397632-1/50016-2  0.68
2006 Fraser JF, Luther N, Kaplitt MG. Neurosurgical Targeting, Delivery, and Infusion of Gene Therapy Agents in the Brain Gene Therapy of the Central Nervous System: From Bench to Bedside. 67-75. DOI: 10.1016/B978-012397632-1/50007-1  0.68
2006 Kaplitt MG, During MJ. Preface Gene Therapy of the Central Nervous System: From Bench to Bedside. xiii-xiv. DOI: 10.1016/B978-012397632-1/50001-0  0.68
2006 Kaplitt MG, During MJ. Gene Therapy of the Central Nervous System: From Bench to Bedside Gene Therapy of the Central Nervous System: From Bench to Bedside.  0.68
2005 Kaplitt MG, Browne S, Stavarache M, Goldfein J, Musatov S. 884 Antiapoptotic Gene Therapy Improves Animal Models of Parkinson's and Huntington's Diseases. Neurosurgery. 57: 424-425. PMID 28184808 DOI: 10.1093/neurosurgery/57.2.424b  0.52
2005 Arkin LM, Sondhi D, Worgall S, Suh LH, Hackett NR, Kaminsky SM, Hosain SA, Souweidane MM, Kaplitt MG, Dyke JP, Heier LA, Ballon DJ, Shungu DC, Wisniewski KE, Greenwald BM, et al. Confronting the issues of therapeutic misconception, enrollment decisions, and personal motives in genetic medicine-based clinical research studies for fatal disorders. Human Gene Therapy. 16: 1028-36. PMID 16149901 DOI: 10.1089/hum.2005.16.1028  0.68
2004 Crystal RG, Sondhi D, Hackett NR, Kaminsky SM, Worgall S, Stieg P, Souweidane M, Hosain S, Heier L, Ballon D, Dinner M, Wisniewski K, Kaplitt M, Greenwald BM, Howell JD, et al. Clinical protocol. Administration of a replication-deficient adeno-associated virus gene transfer vector expressing the human CLN2 cDNA to the brain of children with late infantile neuronal ceroid lipofuscinosis. Human Gene Therapy. 15: 1131-54. PMID 15610613 DOI: 10.1089/hum.2004.15.1131  0.68
2004 Musatov S, Roberts J, Brooks AI, Pena J, Betchen S, Pfaff DW, Kaplitt MG. Inhibition of neuronal phenotype by PTEN in PC12 cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 3627-31. PMID 14990793 DOI: 10.1073/pnas.0308289101  0.32
2004 Hamani C, Saint-Cyr JA, Fraser J, Kaplitt M, Lozano AM. The subthalamic nucleus in the context of movement disorders Brain. 127: 4-20. PMID 14607789 DOI: 10.1093/brain/awh029  0.68
2003 Betchen SA, Kaplitt M. Future and current surgical therapies in Parkinson's disease Current Opinion in Neurology. 16: 487-493. PMID 12869808 DOI: 10.1097/00019052-200308000-00008  0.68
2002 Musatov S, Roberts J, Pfaff D, Kaplitt M. A cis-acting element that directs circular adeno-associated virus replication and packaging Journal of Virology. 76: 12792-12802. PMID 12438604 DOI: 10.1128/JVI.76.24.12792-12802.2002  0.68
2002 Luo J, Kaplitt MG, Fitzsimons HL, Zuzga DS, Liu Y, Oshinsky ML, During MJ. Subthalamic GAD gene therapy in a Parkinson's disease rat model. Science (New York, N.Y.). 298: 425-9. PMID 12376704 DOI: 10.1126/science.1074549  0.68
2002 Kaplitt M, Lozano AM, Montgomery E, Rezai AR. Behavioral and morphological comparison of two nonhuman primate models of Huntington's disease: Comments Neurosurgery. 50: 145-146.  0.68
2001 Kaplitt MG, Lozano AM. Surgical drug delivery for neurodegenerative diseases. Clinical Neurosurgery. 48: 127-44. PMID 11692636  0.68
2001 During MJ, Kaplitt MG, Stern MB, Eidelberg D. Subthalamic GAD gene transfer in Parkinson disease patients who are candidates for deep brain stimulation. Human Gene Therapy. 12: 1589-91. PMID 11529246  0.68
2001 Bilsky MH, Downey RJ, Kaplitt MG, Elowitz EH, Rusch VW. Tension pneumocephalus resulting from iatrogenic subarachnoid-pleural fistulae: report of three cases. The Annals of Thoracic Surgery. 71: 455-7. PMID 11235688 DOI: 10.1016/S0003-4975(00)02339-0  0.68
1999 Kanno H, Hattori S, Sato H, Murata H, Huang FH, Hayashi A, Suzuki N, Yamamoto I, Kawamoto S, Minami M, Miyatake S, Shuin T, Kaplitt MG. Experimental gene therapy against subcutaneously implanted glioma with a herpes simplex virus-defective vector expressing interferon-gamma. Cancer Gene Therapy. 6: 147-54. PMID 10195881 DOI: 10.1038/sj.cgt.7700008  0.68
1999 Thomas DL, Shin S, Jiang BH, Vogel H, Ross MA, Kaplitt M, Shenk TE, Javier RT. Early region 1 transforming functions are dispensable for mammary tumorigenesis by human adenovirus type 9. Journal of Virology. 73: 3071-9. PMID 10074157  0.68
1998 During MJ, Xu R, Young D, Kaplitt MG, Sherwin RS, Leone P. Peroral gene therapy of lactose intolerance using an adeno-associated virus vector. Nature Medicine. 4: 1131-5. PMID 9771745 DOI: 10.1038/2625  0.68
1998 During MJ, Samulski RJ, Elsworth JD, Kaplitt MG, Leone P, Xiao X, Li J, Freese A, Taylor JR, Roth RH, Sladek JR, O'Malley KL, Redmond DE. In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector. Gene Therapy. 5: 820-7. PMID 9747462 DOI: 10.1038/sj.gt.3300650  0.68
1998 Kaplitt MG, Darakchiev B, During MJ. Prospects for gene therapy in pediatric neurosurgery. Pediatric Neurosurgery. 28: 3-14. PMID 9693323 DOI: 10.1159/000028611  0.68
1998 Yin J, Kaplitt MG, Kwong AD, Pfaff DW. In situ PCR for in vivo detection of foreign genes transferred into rat brain. Brain Research. 783: 347-54. PMID 9507188 DOI: 10.1016/S0006-8993(97)00943-8  0.68
1997 Freese A, Kaplitt MG, O'Connor WM, Abbey M, Langer D, Leone P, O'Connor MJ, During MJ. Direct gene transfer into human epileptogenic hippocampal tissue with an adeno-associated virus vector: implications for a gene therapy approach to epilepsy. Epilepsia. 38: 759-66. PMID 9579902 DOI: 10.1111/j.1528-1157.1997.tb01462.x  0.68
1997 Sugiyama A, Hattori S, Tanaka S, Isoda F, Kleopoulos S, Rosenfeld M, Kaplitt M, Sekihara H, Mobbs C. Defective adenoassociated viral-mediated transfection of insulin gene by direct injection into liver parenchyma decreases blood glucose of diabetic mice Hormone and Metabolic Research. 29: 599-603. PMID 9497894  0.68
1997 O'Connor WM, Davidson BL, Kaplitt MG, Abbey MV, During MJ, Leone P, Langer D, O'Connor MJ, Freese A. Adenovirus vector-mediated gene transfer into human epileptogenic brain slices: prospects for gene therapy in epilepsy. Experimental Neurology. 148: 167-78. PMID 9398459 DOI: 10.1006/exnr.1997.6658  0.68
1997 Holtmaat AJ, Hermens WT, Sonnemans MA, Giger RJ, Van Leeuwen FW, Kaplitt MG, Oestreicher AB, Gispen WH, Verhaagen J. Adenoviral vector-mediated expression of B-50/GAP-43 induces alterations in the membrane organization of olfactory axon terminals in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 6575-86. PMID 9254670  0.68
1997 Rosenfeld MR, Bergman I, Schramm L, Griffin JA, Kaplitt MG, Meneses PI. Adeno-associated viral vector gene transfer into leptomeningeal xenografts. Journal of Neuro-Oncology. 34: 139-44. PMID 9210060 DOI: 10.1023/A:1005702228721  0.68
1997 Kaplitt MG, Makimura H. Defective viral vectors as agents for gene transfer in the nervous system. Journal of Neuroscience Methods. 71: 125-32. PMID 9125381 DOI: 10.1016/S0165-0270(96)00132-X  0.68
1997 Samulski RJ, During MJ, Kaplitt MG, Xiao X, Redman G, McCown T. Adeno-associated virus vectors yield long-term expression and delivery of potentially therapeutic genes into non-dividing neuronal cells Journal of Neurovirology. 3: S72.  0.68
1996 Kaplitt M, Gouras GK, Makimura H, Jovanovic J, Sweeney D, Greengard P, Relkin NR, Gandy S. Apolipoprotein E, A beta-amyloid, and the molecular pathology of Alzheimer's disease. Therapeutic implications. Annals of the New York Academy of Sciences. 802: 42-9. PMID 8993483 DOI: 10.1111/j.1749-6632.1996.tb32597.x  0.68
1996 Freese A, During MJ, Davidson BL, Gennarelli TA, Kaplitt MG, Flamm ES, Snyder PJ. Transfection of human lactotroph adenoma cells with an adenovirus vector expressing tyrosine hydroxylase decreases prolactin release. The Journal of Clinical Endocrinology and Metabolism. 81: 2401-4. PMID 8964885 DOI: 10.1210/jcem.81.6.8964885  0.68
1996 Kaplitt MG, Pfaff DW. Viral Vectors for Gene Delivery and Expression in the CNS Methods (San Diego, Calif.). 10: 343-50. PMID 8954846 DOI: 10.1006/meth.1996.0112  0.68
1996 Holtmaat AJ, Hermens WT, Oestreicher AB, Gispen WH, Kaplitt MG, Verhaagen J. Efficient adenoviral vector-directed expression of a foreign gene to neurons and sustentacular cells in the mouse olfactory neuroepithelium. Brain Research. Molecular Brain Research. 41: 148-56. PMID 8883946 DOI: 10.1016/0169-328X(96)00085-X  0.68
1996 Freese A, Stern M, Kaplitt MG, O'Connor WM, Abbey MV, O'Connor MJ, During MJ. Prospects for gene therapy in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 11: 469-88. PMID 8866488 DOI: 10.1002/mds.870110502  0.68
1996 Vogt L, Giger RJ, Ziegler U, Kunz B, Buchstaller A, Hermens WTJMC, Kaplitt MG, Rosenfeld MR, Pfaff DW, Verhaagen J, Sonderegger P. Continuous renewal of the axonal pathway sensor apparatus by insertion of new sensor molecules into the growth cone membrane. Current Biology : Cb. 6: 1153-8. PMID 8805367 DOI: 10.1016/S0960-9822(02)70682-9  0.68
1995 Tjuvajev J, Gansbacher B, Desai R, Beattie B, Kaplitt M, Matei C, Koutcher J, Gilboa E, Blasberg R. RG-2 glioma growth attenuation and severe brain edema caused by local production of interleukin-2 and interferon-gamma. Cancer Research. 55: 1902-10. PMID 7728757  0.68
1995 Rosenfeld MR, Meneses P, Dalmau J, Drobnjak M, Cordon-Cardo C, Kaplitt MG. Gene transfer of wild-type p53 results in restoration of tumor-suppressor function in a medulloblastoma cell line. Neurology. 45: 1533-9. PMID 7644054 DOI: 10.1212/WNL.45.8.1533  0.68
1995 Kaplitt MG. Long-term gene expression and phenotypic correction using adeno-associated virus vectors in mammalian brain Trends in Genetics. 11: 11.  0.68
1994 Verhaagen J, Hermens WT, Kaplitt MG, Pfaff DW, Gispen WH. B-50/GAP-43 expression via a defective herpes simplex virus vector results in persistent morphological changes in non-neuronal cells. Gene Therapy. 1: S81. PMID 8542427  0.68
1994 Kaplitt MG, Kwong AD, Kleopoulos SP, Mobbs CV, Rabkin SD, Pfaff DW. Preproenkephalin promoter yields region-specific and long-term expression in adult brain after direct in vivo gene transfer via a defective herpes simplex viral vector. Proceedings of the National Academy of Sciences of the United States of America. 91: 8979-83. PMID 8090756 DOI: 10.1073/pnas.91.19.8979  0.68
1994 Kaplitt MG, Tjuvajev JG, Leib DA, Berk J, Pettigrew KD, Posner JB, Pfaff DW, Rabkin SD, Blasberg RG. Mutant herpes simplex virus induced regression of tumors growing in immunocompetent rats. Journal of Neuro-Oncology. 19: 137-47. PMID 7964989 DOI: 10.1007/BF01306455  0.68
1994 Verhaagen J, Hermens WT, Oestreicher AB, Gispen WH, Rabkin SD, Pfaff DW, Kaplitt MG. Expression of the growth-associated protein B-50/GAP43 via a defective herpes-simplex virus vector results in profound morphological changes in non-neuronal cells. Brain Research. Molecular Brain Research. 26: 26-36. PMID 7854056 DOI: 10.1016/0169-328X(94)90070-1  0.68
1994 Eizenberg O, Kaplitt MG, Eitan S, Pfaff DW, Hirschberg DL, Schwartz M. Linear dimeric interleukin-2 obtained by the use of a defective herpes simplex viral vector: conformation-activity relationship. Brain Research. Molecular Brain Research. 26: 156-62. PMID 7854042 DOI: 10.1016/0169-328X(94)90086-8  0.68
1994 Kaplitt MG, Leone P, Samulski RJ, Xiao X, Pfaff DW, O'Malley KL, During MJ. Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nature Genetics. 8: 148-54. PMID 7842013 DOI: 10.1038/ng1094-148  0.68
1994 Wood MJ, Byrnes AP, Kaplitt MG, Pfaff DW, Rabkin SD, Charlton HM. Specific patterns of defective HSV-1 gene transfer in the adult central nervous system: implications for gene targeting. Experimental Neurology. 130: 127-40. PMID 7821388 DOI: 10.1006/exnr.1994.1192  0.68
1993 Kaplitt MG, Kleopoulos SP, Pfaff DW, Mobbs CV. Estrogen increases HIP-70/PLC-alpha messenger ribonucleic acid in the rat uterus and hypothalamus. Endocrinology. 133: 99-104. PMID 8319593 DOI: 10.1210/endo.133.1.8319593  0.68
1993 Brooks PJ, Kaplitt MG, Kleopoulos SP, Funabashi T, Mobbs CV, Pfaff DW. Detection of messenger RNA and low-abundance heteronuclear RNA with single-stranded DNA probes produced by amplified primer extension labeling. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 41: 1761-6. PMID 8245424  0.68
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