| Year |
Citation |
Score |
| 2020 |
Rezai AR, Ranjan M, D'Haese PF, Haut MW, Carpenter J, Najib U, Mehta RI, Chazen JL, Zibly Z, Yates JR, Hodder SL, Kaplitt M. Noninvasive hippocampal blood-brain barrier opening in Alzheimer's disease with focused ultrasound. Proceedings of the National Academy of Sciences of the United States of America. PMID 32284421 DOI: 10.1073/Pnas.2002571117 |
0.309 |
|
| 2019 |
Carrillo-Reid L, Day M, Xie Z, Melendez AE, Kondapalli J, Plotkin JL, Wokosin DL, Chen Y, Kress GJ, Kaplitt M, Ilijic E, Guzman JN, Chan SS, Surmeier DJ. Mutant huntingtin enhances activation of dendritic Kv4 K channels in striatal spiny projection neurons. Elife. 8. PMID 31017573 DOI: 10.7554/Elife.40818 |
0.344 |
|
| 2018 |
Niethammer M, Tang CC, Vo A, Nguyen N, Spetsieris P, Dhawan V, Ma Y, Small M, Feigin A, During MJ, Kaplitt MG, Eidelberg D. Gene therapy reduces Parkinson's disease symptoms by reorganizing functional brain connectivity. Science Translational Medicine. 10. PMID 30487248 DOI: 10.1126/Scitranslmed.Aau0713 |
0.354 |
|
| 2018 |
Stavarache MA, Petersen N, Jurgens EM, Milstein ER, Rosenfeld ZB, Ballon DJ, Kaplitt MG. Safe and stable noninvasive focal gene delivery to the mammalian brain following focused ultrasound. Journal of Neurosurgery. 1-10. PMID 29701544 DOI: 10.3171/2017.8.Jns17790 |
0.764 |
|
| 2017 |
Kelm-Nelson CA, Brauer AFL, Barth KJ, Lake JM, Sinnen MLK, Stehula FJ, Muslu C, Marongiu R, Kaplitt MG, Ciucci MR. Characterization of early-onset motor deficits in the Pink1 -/- mouse model of Parkinson disease. Brain Research. PMID 29229503 DOI: 10.1016/J.Brainres.2017.12.002 |
0.749 |
|
| 2017 |
Niethammer M, Tang CC, LeWitt PA, Rezai AR, Leehey MA, Ojemann SG, Flaherty AW, Eskandar EN, Kostyk SK, Sarkar A, Siddiqui MS, Tatter SB, Schwalb JM, Poston KL, Henderson JM, ... ... Kaplitt MG, et al. Long-term follow-up of a randomized AAV2-GAD gene therapy trial for Parkinson's disease. Jci Insight. 2: e90133. PMID 28405611 DOI: 10.1172/Jci.Insight.90133 |
0.331 |
|
| 2017 |
Schweitzer M, Stavarache M, Petersen N, Bakas S, Tsiouris AJ, Davatzikos C, Kaplitt MG, Souweidane MM. SCDT-37. MODULATION OF CONVECTION ENHANCED DELIVERY (CED) DISTRIBUTION USING FOCUSED ULTRASOUND (FUS) Neuro-Oncology. 19: vi272-vi272. DOI: 10.1093/Neuonc/Nox168.1118 |
0.724 |
|
| 2016 |
Marongiu R, Arango-Lievano M, Francardo V, Morgenstern P, Zhang X, Cenci MA, Svenningsson P, Greengard P, Kaplitt MG. Gene therapy blockade of dorsal striatal p11 improves motor function and dyskinesia in parkinsonian mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787858 DOI: 10.1073/Pnas.1524387113 |
0.764 |
|
| 2016 |
Schintu N, Zhang X, Alvarsson A, Marongiu R, Kaplitt MG, Greengard P, Svenningsson P. p11 modulates L-DOPA therapeutic effects and dyskinesia via distinct cell types in experimental Parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787846 DOI: 10.1073/Pnas.1524303113 |
0.755 |
|
| 2016 |
Virk MS, Sagi Y, Medrihan L, Leung J, Kaplitt MG, Greengard P. Opposing roles for serotonin in cholinergic neurons of the ventral and dorsal striatum. Proceedings of the National Academy of Sciences of the United States of America. PMID 26733685 DOI: 10.1073/Pnas.1524183113 |
0.474 |
|
| 2015 |
Stavarache MA, Musatov S, McGill M, Vernov M, Kaplitt MG. The tumor suppressor PTEN regulates motor responses to striatal dopamine in normal and Parkinsonian animals. Neurobiology of Disease. 82: 487-494. PMID 26232589 DOI: 10.1016/J.Nbd.2015.07.013 |
0.367 |
|
| 2015 |
Sagi Y, Heiman M, Peterson JD, Musatov S, Scarduzio M, Logan SM, Kaplitt MG, Surmeier DJ, Heintz N, Greengard P. Erratum: Nitric oxide regulates synaptic transmission between spiny projection neurons (Proc Natl Acad Sci USA (2014) 111 49 (17636-17641) DOI: 10.1073/pnas.1420162111) Proceedings of the National Academy of Sciences of the United States of America. 112. PMID 25787251 DOI: 10.1073/Pnas.1504794112 |
0.412 |
|
| 2015 |
Gürsel DB, Banu MA, Berry N, Marongiu R, Burkhardt JK, Kobylarz K, Kaplitt MG, Rafii S, Boockvar JA. Tight regulation between cell survival and programmed cell death in GBM stem-like cells by EGFR/GSK3b/PP2A signaling. Journal of Neuro-Oncology. 121: 19-29. PMID 25344882 DOI: 10.1007/S11060-014-1602-3 |
0.73 |
|
| 2014 |
Sagi Y, Heiman M, Peterson JD, Musatov S, Scarduzio M, Logan SM, Kaplitt MG, Surmeier DJ, Heintz N, Greengard P. Nitric oxide regulates synaptic transmission between spiny projection neurons. Proceedings of the National Academy of Sciences of the United States of America. 111: 17636-41. PMID 25413364 DOI: 10.1073/Pnas.1420162111 |
0.441 |
|
| 2014 |
Plotkin JL, Day M, Peterson JD, Xie Z, Kress GJ, Rafalovich I, Kondapalli J, Gertler TS, Flajolet M, Greengard P, Stavarache M, Kaplitt MG, Rosinski J, Chan CS, Surmeier DJ. Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington's disease. Neuron. 83: 178-88. PMID 24991961 DOI: 10.1016/J.Neuron.2014.05.032 |
0.482 |
|
| 2014 |
Arango-Lievano M, Schwarz JT, Vernov M, Wilkinson MB, Bradbury K, Feliz A, Marongiu R, Gelfand Y, Warner-Schmidt J, Nestler EJ, Greengard P, Russo SJ, Kaplitt MG. Cell-type specific expression of p11 controls cocaine reward. Biological Psychiatry. 76: 794-801. PMID 24725970 DOI: 10.1016/J.Biopsych.2014.02.012 |
0.724 |
|
| 2013 |
Eriksson TM, Alvarsson A, Stan TL, Zhang X, Hascup KN, Hascup ER, Kehr J, Gerhardt GA, Warner-Schmidt J, Arango-Lievano M, Kaplitt MG, Ogren SO, Greengard P, Svenningsson P. Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11. Molecular Psychiatry. 18: 1096-105. PMID 23032875 DOI: 10.1038/Mp.2012.130 |
0.747 |
|
| 2012 |
Sondhi D, Johnson L, Purpura K, Monette S, Souweidane MM, Kaplitt MG, Kosofsky B, Yohay K, Ballon D, Dyke J, Kaminksy SM, Hackett NR, Crystal RG. Long-term expression and safety of administration of AAVrh.10hCLN2 to the brain of rats and nonhuman primates for the treatment of late infantile neuronal ceroid lipofuscinosis. Human Gene Therapy Methods. 23: 324-35. PMID 23131032 DOI: 10.1089/Hgtb.2012.120 |
0.32 |
|
| 2012 |
Warner-Schmidt JL, Schmidt EF, Marshall JJ, Rubin AJ, Arango-Lievano M, Kaplitt MG, Ibañez-Tallon I, Heintz N, Greengard P. Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior. Proceedings of the National Academy of Sciences of the United States of America. 109: 11360-5. PMID 22733786 DOI: 10.1073/Pnas.1209293109 |
0.75 |
|
| 2011 |
Morgenstern PF, Marongiu R, Musatov SA, Kaplitt MG. Adeno-associated viral gene delivery in neurodegenerative disease. Methods in Molecular Biology (Clifton, N.J.). 793: 443-55. PMID 21913118 DOI: 10.1007/978-1-61779-328-8_29 |
0.755 |
|
| 2011 |
LeWitt PA, Rezai AR, Leehey MA, Ojemann SG, Flaherty AW, Eskandar EN, Kostyk SK, Thomas K, Sarkar A, Siddiqui MS, Tatter SB, Schwalb JM, Poston KL, Henderson JM, Kurlan RM, ... ... Kaplitt MG, et al. AAV2-GAD gene therapy for advanced Parkinson's disease: a double-blind, sham-surgery controlled, randomised trial. The Lancet. Neurology. 10: 309-19. PMID 21419704 DOI: 10.1016/S1474-4422(11)70039-4 |
0.337 |
|
| 2010 |
Alexander B, Warner-Schmidt J, Eriksson T, Tamminga C, Arango-Lievano M, Arango-Llievano M, Ghose S, Vernov M, Stavarache M, Stavarche M, Musatov S, Flajolet M, Svenningsson P, Greengard P, Kaplitt MG. Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens. Science Translational Medicine. 2: 54ra76. PMID 20962330 DOI: 10.1126/Scitranslmed.3001079 |
0.785 |
|
| 2010 |
Souweidane MM, Fraser JF, Arkin LM, Sondhi D, Hackett NR, Kaminsky SM, Heier L, Kosofsky BE, Worgall S, Crystal RG, Kaplitt MG. Gene therapy for late infantile neuronal ceroid lipofuscinosis: neurosurgical considerations. Journal of Neurosurgery. Pediatrics. 6: 115-22. PMID 20672930 DOI: 10.3171/2010.4.Peds09507 |
0.317 |
|
| 2010 |
Alexander B, Warner-Schmidt J, Eriksson T, Tamminga C, Arango-Lievano M, Ghose S, Vernov M, Stavarache M, Musatov S, Flajolet M, Svenningsson P, Greengard P, Kaplitt MG. Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens (Science Translational Medicine (2010) 2, (62er4)) Science Translational Medicine. 2. DOI: 10.1126/Scitranslmed.3001996 |
0.776 |
|
| 2010 |
Alexander B, Warner-Schmidt J, Eriksson T, Tamminga C, Arango-Llievano M, Ghose S, Vernov M, Stavarche M, Musatov S, Flajolet M, Svenningsson P, Greengard P, Kaplitt MG. Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens (Science Translational Medicine (2010) 2, (55er3)) Science Translational Medicine. 2. DOI: 10.1126/scitranslmed.3001841 |
0.768 |
|
| 2009 |
Schultz KN, von Esenwein SA, Hu M, Bennett AL, Kennedy RT, Musatov S, Toran-Allerand CD, Kaplitt MG, Young LJ, Becker JB. Viral vector-mediated overexpression of estrogen receptor-alpha in striatum enhances the estradiol-induced motor activity in female rats and estradiol-modulated GABA release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1897-903. PMID 19211896 DOI: 10.1523/Jneurosci.4647-08.2009 |
0.328 |
|
| 2007 |
Feigin A, Kaplitt MG, Tang C, Lin T, Mattis P, Dhawan V, During MJ, Eidelberg D. Modulation of metabolic brain networks after subthalamic gene therapy for Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 104: 19559-64. PMID 18042721 DOI: 10.1073/Pnas.0706006104 |
0.328 |
|
| 2007 |
Kaplitt MG, Feigin A, Tang C, Fitzsimons HL, Mattis P, Lawlor PA, Bland RJ, Young D, Strybing K, Eidelberg D, During MJ. Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial. Lancet. 369: 2097-105. PMID 17586305 DOI: 10.1016/S0140-6736(07)60982-9 |
0.369 |
|
| 2007 |
Emborg ME, Carbon M, Holden JE, During MJ, Ma Y, Tang C, Moirano J, Fitzsimons H, Roitberg BZ, Tuccar E, Roberts A, Kaplitt MG, Eidelberg D. Subthalamic glutamic acid decarboxylase gene therapy: changes in motor function and cortical metabolism. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 501-9. PMID 16835631 DOI: 10.1038/Sj.Jcbfm.9600364 |
0.36 |
|
| 2006 |
Asanuma K, Tang C, Ma Y, Dhawan V, Mattis P, Edwards C, Kaplitt MG, Feigin A, Eidelberg D. Network modulation in the treatment of Parkinson's disease. Brain : a Journal of Neurology. 129: 2667-78. PMID 16844713 DOI: 10.1093/Brain/Awl162 |
0.34 |
|
| 2006 |
Musatov S, Chen W, Pfaff DW, Kaplitt MG, Ogawa S. RNAi-mediated silencing of estrogen receptor {alpha} in the ventromedial nucleus of hypothalamus abolishes female sexual behaviors. Proceedings of the National Academy of Sciences of the United States of America. 103: 10456-60. PMID 16803960 DOI: 10.1073/Pnas.0603045103 |
0.341 |
|
| 2006 |
Cooper LB, Chan DK, Roediger FC, Shaffer BR, Fraser JF, Musatov S, Selesnick SH, Kaplitt MG. AAV-mediated delivery of the caspase inhibitor XIAP protects against cisplatin ototoxicity. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 27: 484-90. PMID 16791039 DOI: 10.1097/01.Mao.0000202647.19355.6A |
0.312 |
|
| 2006 |
Kaplitt MG, Eidelberg D, Feigin A, Fitzimmons H, Lawlor P, Strybing K, Cox M, Tang C, Bland R, During MJ. 727. Improvements in Clinical and Radiographic Outcomes in a Phase I Study of AAV-GAD Gene Therapy for Parkinson's Disease Molecular Therapy. 13: S280-S281. DOI: 10.1016/J.Ymthe.2006.08.807 |
0.303 |
|
| 2005 |
Kaplitt MG, Browne S, Stavarache M, Goldfein J, Musatov S. 884 Antiapoptotic Gene Therapy Improves Animal Models of Parkinson's and Huntington's Diseases. Neurosurgery. 57: 424-425. PMID 28184808 DOI: 10.1093/Neurosurgery/57.2.424B |
0.323 |
|
| 2005 |
Hackett NR, Sondhi D, Kaminsky SM, Worgall S, Arkin LA, Hollmann CA, Shungu DC, Mao X, Dyke JP, Heier L, Souweidane M, Kaplitt M, Crystal RG. 969. Development of Non-Invasive Imaging Strategies to Assess the Impact of Gene Therapy: Phenotypic Assessment of the Neurodegenerative CNS Disorder Late Infantile Neuronal Ceroid Lipofuscinosis Using Magnetic Resonance Spectroscopy Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.512 |
0.334 |
|
| 2004 |
Crystal RG, Sondhi D, Hackett NR, Kaminsky SM, Worgall S, Stieg P, Souweidane M, Hosain S, Heier L, Ballon D, Dinner M, Wisniewski K, Kaplitt M, Greenwald BM, Howell JD, et al. Clinical protocol. Administration of a replication-deficient adeno-associated virus gene transfer vector expressing the human CLN2 cDNA to the brain of children with late infantile neuronal ceroid lipofuscinosis. Human Gene Therapy. 15: 1131-54. PMID 15610613 DOI: 10.1089/Hum.2004.15.1131 |
0.356 |
|
| 2004 |
Musatov S, Roberts J, Brooks AI, Pena J, Betchen S, Pfaff DW, Kaplitt MG. Inhibition of neuronal phenotype by PTEN in PC12 cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 3627-31. PMID 14990793 DOI: 10.1073/Pnas.0308289101 |
0.323 |
|
| 2004 |
Hamani C, Saint-Cyr JA, Fraser J, Kaplitt M, Lozano AM. The subthalamic nucleus in the context of movement disorders Brain. 127: 4-20. PMID 14607789 DOI: 10.1093/Brain/Awh029 |
0.353 |
|
| 2003 |
Scott RE, Wu-Peng XS, Kaplitt MG, Pfaff DW. Gene transfer and in vivo promoter analysis of the rat progesterone receptor using a herpes simplex virus viral vector. Brain Research. Molecular Brain Research. 114: 91-100. PMID 12829318 DOI: 10.1016/S0169-328X(03)00084-6 |
0.325 |
|
| 2002 |
Luo J, Kaplitt MG, Fitzsimons HL, Zuzga DS, Liu Y, Oshinsky ML, During MJ. Subthalamic GAD gene therapy in a Parkinson's disease rat model. Science (New York, N.Y.). 298: 425-9. PMID 12376704 DOI: 10.1126/Science.1074549 |
0.382 |
|
| 1998 |
During MJ, Xu R, Young D, Kaplitt MG, Sherwin RS, Leone P. Peroral gene therapy of lactose intolerance using an adeno-associated virus vector. Nature Medicine. 4: 1131-5. PMID 9771745 DOI: 10.1038/2625 |
0.328 |
|
| 1998 |
During MJ, Samulski RJ, Elsworth JD, Kaplitt MG, Leone P, Xiao X, Li J, Freese A, Taylor JR, Roth RH, Sladek JR, O'Malley KL, Redmond DE. In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector. Gene Therapy. 5: 820-7. PMID 9747462 DOI: 10.1038/Sj.Gt.3300650 |
0.371 |
|
| 1998 |
Kaplitt MG, Darakchiev B, During MJ. Prospects for gene therapy in pediatric neurosurgery. Pediatric Neurosurgery. 28: 3-14. PMID 9693323 DOI: 10.1159/000028611 |
0.348 |
|
| 1997 |
Freese A, Kaplitt MG, O'Connor WM, Abbey M, Langer D, Leone P, O'Connor MJ, During MJ. Direct gene transfer into human epileptogenic hippocampal tissue with an adeno-associated virus vector: implications for a gene therapy approach to epilepsy. Epilepsia. 38: 759-66. PMID 9579902 DOI: 10.1111/J.1528-1157.1997.Tb01462.X |
0.346 |
|
| 1997 |
O'Connor WM, Davidson BL, Kaplitt MG, Abbey MV, During MJ, Leone P, Langer D, O'Connor MJ, Freese A. Adenovirus vector-mediated gene transfer into human epileptogenic brain slices: prospects for gene therapy in epilepsy. Experimental Neurology. 148: 167-78. PMID 9398459 DOI: 10.1006/Exnr.1997.6658 |
0.347 |
|
| 1997 |
Rosenfeld MR, Bergman I, Schramm L, Griffin JA, Kaplitt MG, Meneses PI. Adeno-associated viral vector gene transfer into leptomeningeal xenografts. Journal of Neuro-Oncology. 34: 139-44. PMID 9210060 DOI: 10.1023/A:1005702228721 |
0.331 |
|
| 1996 |
Kaplitt M, Gouras GK, Makimura H, Jovanovic J, Sweeney D, Greengard P, Relkin NR, Gandy S. Apolipoprotein E, A beta-amyloid, and the molecular pathology of Alzheimer's disease. Therapeutic implications. Annals of the New York Academy of Sciences. 802: 42-9. PMID 8993483 DOI: 10.1111/J.1749-6632.1996.Tb32597.X |
0.698 |
|
| 1996 |
Freese A, During MJ, Davidson BL, Gennarelli TA, Kaplitt MG, Flamm ES, Snyder PJ. Transfection of human lactotroph adenoma cells with an adenovirus vector expressing tyrosine hydroxylase decreases prolactin release. The Journal of Clinical Endocrinology and Metabolism. 81: 2401-4. PMID 8964885 DOI: 10.1210/Jcem.81.6.8964885 |
0.335 |
|
| 1996 |
Kaplitt MG, Pfaff DW. Viral Vectors for Gene Delivery and Expression in the CNS Methods (San Diego, Calif.). 10: 343-50. PMID 8954846 DOI: 10.1006/Meth.1996.0112 |
0.323 |
|
| 1996 |
Holtmaat AJ, Hermens WT, Oestreicher AB, Gispen WH, Kaplitt MG, Verhaagen J. Efficient adenoviral vector-directed expression of a foreign gene to neurons and sustentacular cells in the mouse olfactory neuroepithelium. Brain Research. Molecular Brain Research. 41: 148-56. PMID 8883946 DOI: 10.1016/0169-328X(96)00085-X |
0.34 |
|
| 1996 |
Freese A, Stern M, Kaplitt MG, O'Connor WM, Abbey MV, O'Connor MJ, During MJ. Prospects for gene therapy in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 11: 469-88. PMID 8866488 DOI: 10.1002/Mds.870110502 |
0.361 |
|
| 1995 |
Rosenfeld MR, Meneses P, Dalmau J, Drobnjak M, Cordon-Cardo C, Kaplitt MG. Gene transfer of wild-type p53 results in restoration of tumor-suppressor function in a medulloblastoma cell line. Neurology. 45: 1533-9. PMID 7644054 DOI: 10.1212/Wnl.45.8.1533 |
0.356 |
|
| 1994 |
Kaplitt MG, Kwong AD, Kleopoulos SP, Mobbs CV, Rabkin SD, Pfaff DW. Preproenkephalin promoter yields region-specific and long-term expression in adult brain after direct in vivo gene transfer via a defective herpes simplex viral vector. Proceedings of the National Academy of Sciences of the United States of America. 91: 8979-83. PMID 8090756 DOI: 10.1073/Pnas.91.19.8979 |
0.312 |
|
| 1994 |
Kaplitt MG, Leone P, Samulski RJ, Xiao X, Pfaff DW, O'Malley KL, During MJ. Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nature Genetics. 8: 148-54. PMID 7842013 DOI: 10.1038/Ng1094-148 |
0.361 |
|
| 1994 |
Wood MJ, Byrnes AP, Kaplitt MG, Pfaff DW, Rabkin SD, Charlton HM. Specific patterns of defective HSV-1 gene transfer in the adult central nervous system: implications for gene targeting. Experimental Neurology. 130: 127-40. PMID 7821388 DOI: 10.1006/Exnr.1994.1192 |
0.342 |
|
| 1991 |
Kaplitt MG, Pfaus JG, Kleopoulos SP, Hanlon BA, Rabkin SD, Pfaff DW. Expression of a functional foreign gene in adult mammalian brain following in Vivo transfer via a herpes simplex virus type 1 defective viral vector. Molecular and Cellular Neurosciences. 2: 320-30. PMID 19912815 DOI: 10.1016/1044-7431(91)90062-S |
0.316 |
|
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