Kjell Fuxe - Publications

Affiliations: 
Department of Neuroscience,Karolinska Institute,stockholm, sweden, Solna, Stockholms län, Sweden 
Area:
receptor mechanisms

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Year Citation  Score
2024 Odagaki Y, Kinoshita M, Palkovits M, Borroto-Escuela DO, Fuxe K. Potential differences in receptor-mediated G-protein activation in postmortem human hippocampal membranes prepared from healthy controls and suicide victims. Neuropsychopharmacology Reports. PMID 39352115 DOI: 10.1002/npr2.12484  0.497
2024 Borroto-Escuela DO, Gonzalez-Cristo E, Ochoa-Torres V, Serra-Rojas EM, Ambrogini P, Arroyo-García LE, Fuxe K. Understanding electrical and chemical transmission in the brain. Frontiers in Cellular Neuroscience. 18: 1398862. PMID 38988663 DOI: 10.3389/fncel.2024.1398862  0.538
2024 Borroto-Escuela DO, Fuxe K. Advancement in human neuroimaging based on proximity ligation assay in brain disease. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 38956177 DOI: 10.1038/s41386-024-01911-5  0.464
2024 Mirchandani-Duque M, Choucri M, Hernández-Mondragón JC, Crespo-Ramírez M, Pérez-Olives C, Ferraro L, Franco R, Pérez de la Mora M, Fuxe K, Borroto-Escuela DO. Membrane Heteroreceptor Complexes as Second-Order Protein Modulators: A Novel Integrative Mechanism through Allosteric Receptor-Receptor Interactions. Membranes. 14. PMID 38786931 DOI: 10.3390/membranes14050096  0.8
2024 Arrabal-Gómez C, Serrano-Castro P, Sánchez-Pérez JA, Garcia-Casares N, Fuxe K, Borroto-Escuela D, Narváez M. Potentiation of antidepressant effects: NPY1R agonist and ketamine synergy enhances TrkB signaling and neurogenesis in the ventral hippocampus. Expert Opinion On Therapeutic Targets. 1-14. PMID 38626283 DOI: 10.1080/14728222.2024.2342524  0.519
2024 Borroto-Escuela D, Serrano-Castro P, Sánchez-Pérez JA, Barbancho-Fernández MA, Fuxe K, Narváez M. Enhanced neuronal survival and BDNF elevation via long-term co-activation of galanin 2 (GALR2) and neuropeptide Y1 receptors (NPY1R): potential therapeutic targets for Major depressive disorder. Expert Opinion On Therapeutic Targets. PMID 38622072 DOI: 10.1080/14728222.2024.2342517  0.555
2024 Beltran-Casanueva R, Hernández-García A, Serrano-Castro PJ, Sánchez-Pérez JA, Barbancho-Fernández MA, García-Casares N, Fuxe K, Borroto-Escuela DO, Narváez M. Long-term enhancements in antidepressant efficacy and neurogenesis: Effects of intranasal co-administration of neuropeptide Y 1 receptor (NPY1R) and galanin receptor 2 (GALR2) agonists in the ventral hippocampus. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 38: e23595. PMID 38572811 DOI: 10.1096/fj.202400087R  0.603
2024 Sánchez-Varo R, López-Salas A, Beltran-Casanueva R, Díaz-Sánchez E, Alvarez-Contino JE, Barbancho-Fernández MA, Serrano-Castro P, Fuxe K, Borroto-Escuela DO, García-Casares N, Narváez M. Enhancement of neurogenesis and cognition through intranasal co-delivery of galanin receptor 2 (GALR2) and neuropeptide Y receptor 1 (NPY1R) agonists: a potential pharmacological strategy for cognitive dysfunctions. Behavioral and Brain Functions : Bbf. 20: 6. PMID 38549164 DOI: 10.1186/s12993-024-00230-5  0.565
2024 Beltran-Casanueva R, Hernández-García A, de Amo García P, Blanco-Reina E, Serrano-Castro P, García-Casares N, Fuxe K, Borroto-Escuela DO, Narváez M. Neuropeptide Y receptor 1 and galanin receptor 2 (NPY1R-GALR2) interactions in the dentate gyrus and their relevance for neurogenesis and cognition. Frontiers in Cellular Neuroscience. 18: 1323986. PMID 38425430 DOI: 10.3389/fncel.2024.1323986  0.567
2023 Hernández-Mondragón JC, Hernández-Hernández DA, Crespo-Ramírez M, Prospero-García O, Rocha-Arrieta L, Fuxe K, Borroto-Escuela DO, Perez de la Mora M. Evidence for the existence of facilitatory interactions between the dopamine D2 receptor and the oxytocin receptor in the amygdala of the rat. Relevance for anxiolytic actions. Frontiers in Pharmacology. 14: 1251922. PMID 37900160 DOI: 10.3389/fphar.2023.1251922  0.816
2023 Romero-Fernandez W, Carvajal-Tapia C, Prusky A, Katdare KA, Wang E, Shostak A, Ventura-Antunes L, Harmsen HJ, Lippmann ES, Fuxe K, MacGurn JA, Borroto-Escuela DO, Schrag MS. Detection, visualization and quantification of protein complexes in human Alzheimer's disease brains using proximity ligation assay. Scientific Reports. 13: 11948. PMID 37488165 DOI: 10.1038/s41598-023-38000-4  0.477
2023 Borroto-Escuela DO, Lopez-Salas A, Wydra K, Bartolini M, Zhou Z, Frankowska M, Suder A, Benitez-Porres J, Romero-Fernandez W, Filip M, Fuxe K. Combined treatment with Sigma1R and A2AR agonists fails to inhibit cocaine self-administration despite causing strong antagonistic accumbal A2AR-D2R complex interactions: the potential role of astrocytes. Frontiers in Molecular Neuroscience. 16: 1106765. PMID 37293542 DOI: 10.3389/fnmol.2023.1106765  0.724
2023 Ambrogini P, Lattanzi D, Pagliarini M, Di Palma M, Sartini S, Cuppini R, Fuxe K, Borroto-Escuela DO. 5HT1AR-FGFR1 Heteroreceptor Complexes Differently Modulate GIRK Currents in the Dorsal Hippocampus and the Dorsal Raphe Serotonin Nucleus of Control Rats and of a Genetic Rat Model of Depression. International Journal of Molecular Sciences. 24. PMID 37108630 DOI: 10.3390/ijms24087467  0.592
2023 Díaz-Sánchez E, López-Salas A, Mirchandani-Duque M, Alvarez-Contino JE, Sánchez-Pérez JA, Fuxe K, Borroto-Escuela DO, García-Casares N, Narváez M. Decreased medial prefrontal cortex activity related to impaired novel object preference task performance following GALR2 and Y1R agonists intranasal infusion. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 161: 114433. PMID 36848750 DOI: 10.1016/j.biopha.2023.114433  0.524
2023 Romero-Fernandez W, Carvajal-Tapia C, Prusky A, Katdare K, Wang E, Shostak A, Ventura-Antunes L, Harmsen H, Lippmann E, Borroto-Escuela D, MacGurn J, Fuxe K, Schrag M. Detection, Visualization and Quantification of Protein Complexes in Human Alzheimer's Disease Brains using Proximity Ligation Assay. Research Square. PMID 36824944 DOI: 10.21203/rs.3.rs-2570335/v1  0.477
2023 Odagaki Y, Mikami M, Kinoshita M, Meana JJ, Callado LF, García-Sevilla JA, Borroto-Escuela DO, Fuxe K. Agonistic properties of a series of psychotropic drugs at 5-HT receptors in rat and human brain membranes determined by [S]GTPγS binding assay. Pharmacological Reports : Pr. PMID 36637685 DOI: 10.1007/s43440-023-00448-6  0.567
2023 Alvarez-Contino JE, Díaz-Sánchez E, Mirchandani-Duque M, Sánchez-Pérez JA, Barbancho MA, López-Salas A, García-Casares N, Fuxe K, Borroto-Escuela DO, Narváez M. GALR2 and Y1R agonists intranasal infusion enhanced adult ventral hippocampal neurogenesis and antidepressant-like effects involving BDNF actions. Journal of Cellular Physiology. PMID 36599082 DOI: 10.1002/jcp.30944  0.566
2022 Borroto-Escuela DO, Cuesta-Marti C, Lopez-Salas A, Chruścicka-Smaga B, Crespo-Ramírez M, Tesoro-Cruz E, Palacios-Lagunas DA, Perez de la Mora M, Schellekens H, Fuxe K. The oxytocin receptor represents a key hub in the GPCR heteroreceptor network: potential relevance for brain and behavior. Frontiers in Molecular Neuroscience. 15: 1055344. PMID 36618821 DOI: 10.3389/fnmol.2022.1055344  0.803
2022 Romero-Fernandez W, Taura JJ, Crans RAJ, Lopez-Cano M, Fores-Pons R, Narváez M, Carlsson J, Ciruela F, Fuxe K, Borroto-Escuela DO. The mGlu Receptor Protomer-Mediated Dopamine D Receptor Trans-Inhibition Is Dependent on the Adenosine A Receptor Protomer: Implications for Parkinson's Disease. Molecular Neurobiology. PMID 35829830 DOI: 10.1007/s12035-022-02946-9  0.619
2022 Mirchandani-Duque M, Barbancho MA, López-Salas A, Alvarez-Contino JE, García-Casares N, Fuxe K, Borroto-Escuela DO, Narváez M. Galanin and Neuropeptide Y Interaction Enhances Proliferation of Granule Precursor Cells and Expression of Neuroprotective Factors in the Rat Hippocampus with Consequent Augmented Spatial Memory. Biomedicines. 10. PMID 35740319 DOI: 10.3390/biomedicines10061297  0.553
2022 Pérez de la Mora M, Borroto-Escuela DO, Crespo-Ramírez M, Rejón-Orantes JDC, Palacios-Lagunas DA, Martínez-Mata MK, Sánchez-Luna D, Tesoro-Cruz E, Fuxe K. Dysfunctional Heteroreceptor Complexes as Novel Targets for the Treatment of Major Depressive and Anxiety Disorders. Cells. 11. PMID 35681521 DOI: 10.3390/cells11111826  0.779
2022 Romero-Fernandez W, Wydra K, Borroto-Escuela DO, Jastrzębska J, Zhou Z, Frankowska M, Filip M, Fuxe K. Increased density and antagonistic allosteric interactions in A2AR-D2R heterocomplexes in extinction from cocaine use, lost in cue induced reinstatement of cocaine seeking. Pharmacology, Biochemistry, and Behavior. 215: 173375. PMID 35307414 DOI: 10.1016/j.pbb.2022.173375  0.532
2022 Borroto-Escuela DO, Fuxe K. The integrative role of G protein-coupled receptor heterocomplexes in Parkinson's disease. Neural Regeneration Research. 17: 2211-2212. PMID 35259834 DOI: 10.4103/1673-5374.335792  0.532
2022 Borroto-Escuela DO, Fores R, Pita M, Barbancho MA, Zamorano-Gonzalez P, Casares NG, Fuxe K, Narváez M. Intranasal Delivery of Galanin 2 and Neuropeptide Y1 Agonists Enhanced Spatial Memory Performance and Neuronal Precursor Cells Proliferation in the Dorsal Hippocampus in Rats. Frontiers in Pharmacology. 13: 820210. PMID 35250569 DOI: 10.3389/fphar.2022.820210  0.556
2022 Borroto-Escuela DO, Ferraro L, Fuxe K. Molecular Integration in Adenosine Heteroreceptor Complexes Through Allosteric and De-Phosphorylation (STEP) Mechanisms and its Role in Brain Disease. Frontiers in Pharmacology. 12: 781381. PMID 35069202 DOI: 10.3389/fphar.2021.781381  0.485
2021 Borroto-Escuela DO, Ferraro L, Beggiato S, Narváez M, Fores-Pons R, Alvarez-Contino JE, Wydra K, Frankowska M, Bader M, Filip M, Fuxe K. Correction to: The coming together of allosteric and phosphorylation mechanisms in the molecular integration of A2A heteroreceptor complexes in the dorsal and ventral striatal-pallidal GABA neurons. Pharmacological Reports : Pr. PMID 34532847 DOI: 10.1007/s43440-021-00326-z  0.524
2021 Borroto-Escuela DO, Ambrogini P, Narvaez M, Di Liberto V, Beggiato S, Ferraro L, Fores-Pons R, Alvarez-Contino JE, Lopez-Salas A, Mudò G, Díaz-Cabiale Z, Fuxe K. Serotonin Heteroreceptor Complexes and Their Integration of Signals in Neurons and Astroglia-Relevance for Mental Diseases. Cells. 10. PMID 34440670 DOI: 10.3390/cells10081902  0.596
2021 Borroto-Escuela DO, Ferraro L, Beggiato S, Narváez M, Fores-Pons R, Alvarez-Contino JE, Wydra K, Frankowska M, Bader M, Filip M, Fuxe K. The coming together of allosteric and phosphorylation mechanisms in the molecular integration of A2A heteroreceptor complexes in the dorsal and ventral striatal-pallidal GABA neurons. Pharmacological Reports : Pr. PMID 34426901 DOI: 10.1007/s43440-021-00314-3  0.605
2021 Beggiato S, Zuccarini M, Cassano T, Borroto-Escuela DO, Di Iorio P, Schwarcz R, Fuxe K, Ferraro L. Adenosine and Kynurenic Acid Interactions: Possible Relevance for Schizophrenia Treatment? Frontiers in Pharmacology. 12: 654426. PMID 33935767 DOI: 10.3389/fphar.2021.654426  0.466
2021 Borroto-Escuela DO, Wydra K, Fores-Pons R, Vasudevan L, Romero-Fernandez W, Frankowska M, Ferraro L, Beggiato S, Crespo-Ramirez M, Rivera A, Rocha LL, Perez de la Mora M, Stove C, Filip M, Fuxe K. The Balance of MU-Opioid, Dopamine D2 and Adenosine A2A Heteroreceptor Complexes in the Ventral Striatal-Pallidal GABA Antireward Neurons May Have a Significant Role in Morphine and Cocaine Use Disorders. Frontiers in Pharmacology. 12: 627032. PMID 33790790 DOI: 10.3389/fphar.2021.627032  0.782
2021 Borroto-Escuela DO, Ambrogini P, Chruścicka B, Lindskog M, Crespo-Ramirez M, Hernández-Mondragón JC, Perez de la Mora M, Schellekens H, Fuxe K. The Role of Central Serotonin Neurons and 5-HT Heteroreceptor Complexes in the Pathophysiology of Depression: A Historical Perspective and Future Prospects. International Journal of Molecular Sciences. 22. PMID 33672070 DOI: 10.3390/ijms22041927  0.793
2020 Chruścicka B, Cowan CSM, Wallace Fitzsimons SE, Borroto-Escuela DO, Druelle CM, Stamou P, Bergmann CA, Dinan TG, Slattery DA, Fuxe K, Cryan JF, Schellekens H. Molecular, biochemical and behavioural evidence for a novel oxytocin receptor and serotonin 2C receptor heterocomplex. Neuropharmacology. 108394. PMID 33188842 DOI: 10.1016/j.neuropharm.2020.108394  0.599
2020 Borroto-Escuela DO, Pita-Rodriguez M, Fores-Pons R, Barbancho MA, Fuxe K, Narváez M. Galanin and neuropeptide Y interactions elicit antidepressant activity linked to neuronal precursor cells of the dentate gyrus in the ventral hippocampus. Journal of Cellular Physiology. PMID 33044017 DOI: 10.1002/jcp.30092  0.562
2020 Di Palma M, Sartini S, Lattanzi D, Cuppini R, Pita-Rodriguez M, Diaz-Carmenate Y, Narvaez M, Fuxe K, Borroto-Escuela DO, Ambrogini P. Evidence for the existence of A2AR-TrkB heteroreceptor complexes in the dorsal hippocampus of the rat brain: Potential implications of A2AR and TrkB interplay upon ageing. Mechanisms of Ageing and Development. 190: 111289. PMID 32565059 DOI: 10.1016/J.Mad.2020.111289  0.615
2020 Wydra K, Gawliński D, Gawlińska K, Frankowska M, Borroto-Escuela DO, Fuxe K, Filip M. Adenosine AReceptors in Substance Use Disorders: A Focus on Cocaine. Cells. 9. PMID 32492952 DOI: 10.3390/Cells9061372  0.636
2020 Borroto-Escuela DO, Ferraro L, Narvaez M, Tanganelli S, Beggiato S, Liu F, Rivera A, Fuxe K. Multiple Adenosine-Dopamine (A2A-D2 Like) Heteroreceptor Complexes in the Brain and Their Role in Schizophrenia. Cells. 9. PMID 32349279 DOI: 10.3390/Cells9051077  0.634
2020 Narváez M, Andrade-Talavera Y, Valladolid-Acebes I, Fredriksson M, Siegele P, Hernandez-Sosa A, Fisahn A, Fuxe K, Borroto-Escuela DO. Existence of FGFR1-5-HT1AR heteroreceptor complexes in hippocampal astrocytes. Putative link to 5-HT and FGF2 modulation of hippocampal gamma oscillations. Neuropharmacology. 170: 108070. PMID 32229140 DOI: 10.1016/J.Neuropharm.2020.108070  0.605
2020 Romero-Fernandez W, Zhou Z, Beggiato S, Wydra K, Filip M, Tanganelli S, Borroto-Escuela DO, Ferraro L, Fuxe K. Acute cocaine treatment enhances the antagonistic allosteric adenosine A2A-dopamine D2 receptor-receptor interactions in rat dorsal striatum without increasing significantly extracellular dopamine levels. Pharmacological Reports : Pr. PMID 32124388 DOI: 10.1007/S43440-020-00069-3  0.686
2020 Fuxe K, Tinner B, Bjelke B, Agnati LF, Verhofstad A, Steinbusch HG, Goldstein M, Hersh L, Kalia M. Monoaminergic and Peptidergic Innervation of the Intermedio-Lateral Horn of the Spinal Cord. The European Journal of Neuroscience. 2: 451-460. PMID 12106031 DOI: 10.1111/J.1460-9568.1990.Tb00436.X  0.315
2019 Borroto-Escuela DO, Wydra K, Romero-Fernandez W, Zhou Z, Frankowska M, Filip M, Fuxe K. A2AR Transmembrane 2 Peptide Administration Disrupts the A2AR-A2AR Homoreceptor but Not the A2AR-D2R Heteroreceptor Complex: Lack of Actions on Rodent Cocaine Self-Administration. International Journal of Molecular Sciences. 20. PMID 31816953 DOI: 10.3390/Ijms20236100  0.605
2019 Borroto-Escuela DO, Romero-Fernandez W, Wydra K, Zhou Z, Suder A, Filip M, Fuxe K. OSU-6162, a Sigma1R Ligand in Low Doses, Can Further Increase the Effects of Cocaine Self-Administration on Accumbal D2R Heteroreceptor Complexes. Neurotoxicity Research. PMID 31782100 DOI: 10.1007/S12640-019-00134-7  0.567
2019 Plach M, Schäfer T, Borroto-Escuela DO, Weikert D, Gmeiner P, Fuxe K, Friedland K. Differential allosteric modulation within dopamine DR - neurotensin NTS1R and DR - serotonin 5-HTR receptor complexes gives bias to intracellular calcium signalling. Scientific Reports. 9: 16312. PMID 31704949 DOI: 10.1038/S41598-019-52540-8  0.664
2019 Spulber S, Conti M, Elberling F, Raciti M, Borroto-Escuela DO, Fuxe K, Ceccatelli S. Desipramine restores the alterations in circadian entrainment induced by prenatal exposure to glucocorticoids. Translational Psychiatry. 9: 263. PMID 31624238 DOI: 10.1038/S41398-019-0594-3  0.548
2019 Borroto-Escuela DO, Fuxe K. Oligomeric Receptor Complexes and Their Allosteric Receptor-Receptor Interactions in the Plasma Membrane Represent a New Biological Principle for Integration of Signals in the CNS. Frontiers in Molecular Neuroscience. 12: 230. PMID 31607863 DOI: 10.3389/Fnmol.2019.00230  0.636
2019 Borroto-Escuela DO, Fuxe K. Can Allosteric Receptor-Protein Interactions in Receptor Complexes Be a Molecular Mechanism Involved in Cancer Immune Therapy? Frontiers in Endocrinology. 10: 574. PMID 31481934 DOI: 10.3389/Fendo.2019.00574  0.6
2019 Zaniewska M, Gawliński D, Wyczesana M, Nowak E, Kula K, Maciów-Głąb M, Jastrzębska J, Sadakierska-Chudy A, Bader M, Fuxe K. Ethanol Intake and A Receptor Overexpression. Neuroscience. PMID 31449988 DOI: 10.1016/j.neuroscience.2019.08.030  0.303
2019 Franco R, Reyes-Resina I, Aguinaga D, Lillo A, Jiménez J, Raïch I, Borroto-Escuela DO, Ferreiro-Vera C, Canela EI, Sánchez de Medina V, Del Ser-Badia A, Fuxe K, Saura CA, Navarro G. Potentiation of cannabinoid signaling in microglia by adenosine A receptor antagonists. Glia. PMID 31429130 DOI: 10.1002/Glia.23694  0.591
2019 Vasudevan L, Borroto-Escuela DO, Huysentruyt J, Fuxe K, Saini DK, Stove C. Heterodimerization of Mu Opioid Receptor Protomer with Dopamine D Receptor Modulates Agonist-Induced Internalization of Mu Opioid Receptor. Biomolecules. 9. PMID 31416253 DOI: 10.3390/biom9080368  0.597
2019 de la Mora MP, Hernandez-Mondragon C, Crespo-Ramirez M, Rejón-Orantes J, Borroto-Escuela DO, Fuxe K. Conventional and Novel Pharmacological Approaches to Treat Dopamine-Related Disorders: Focus on Parkinson's Disease and Schizophrenia. Neuroscience. PMID 31349007 DOI: 10.1016/J.Neuroscience.2019.07.026  0.666
2019 Borroto-Escuela DO, Fuxe K. On the G Protein-Coupled Receptor Neuromodulation of the Claustrum. Neurochemical Research. PMID 31172348 DOI: 10.1007/S11064-019-02822-4  0.671
2019 Flores-Burgess A, Millón C, Gago B, García-Durán L, Cantero-García N, Coveñas R, Narváez JA, Fuxe K, Santín L, Díaz-Cabiale Z. Galanin (1-15)-fluoxetine interaction in the novel object recognition test. Involvement of 5-HT1A receptors in the prefrontal cortex of the rats. Neuropharmacology. 155: 104-112. PMID 31128121 DOI: 10.1016/j.neuropharm.2019.05.023  0.363
2019 Fuxe K, Borroto-Escuela DO. Understanding receptor heteromerization and its allosteric integration of signals. Neuropharmacology. PMID 31054939 DOI: 10.1016/j.neuropharm.2019.05.001  0.603
2019 Chruścicka B, Wallace Fitzsimons SE, Borroto-Escuela DO, Druelle C, Stamou P, Nally K, Dinan TG, Cryan JF, Fuxe K, Schellekens H. Attenuation of Oxytocin and Serotonin 2A Receptor Signalling through Novel Heteroreceptor Formation. Acs Chemical Neuroscience. PMID 31038917 DOI: 10.1021/Acschemneuro.8B00665  0.634
2019 Borroto-Escuela DO, Narváez M, Romero-Fernández W, Pinton L, Wydra K, Filip M, Beggiato S, Tanganelli S, Ferraro L, Fuxe K. Acute Cocaine Enhances Dopamine DR Recognition and Signaling and Counteracts DR Internalization in Sigma1R-DR Heteroreceptor Complexes. Molecular Neurobiology. PMID 30972626 DOI: 10.1007/S12035-019-1580-8  0.796
2019 Borroto-Escuela DO, Fuxe K. Adenosine heteroreceptor complexes in the basal ganglia are implicated in Parkinson's disease and its treatment. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 30637481 DOI: 10.1007/S00702-019-01969-2  0.64
2019 Fuxe K, Tinner B, Bjelke B, Agnati LF, Verhofstad A, Steinbusch HG, Goldstein M, Kalia M. Monoaminergic and Peptidergic Innervation of the Intermedio-Lateral Horn of the Spinal Cord. The European Journal of Neuroscience. 2: 430-450. PMID 12106030 DOI: 10.1111/j.1460-9568.1990.tb00435.x  0.307
2018 Borroto-Escuela DO, Tarakanov AO, Brito I, Fuxe K. Glutamate heteroreceptor complexes in the brain. Pharmacological Reports : Pr. 70: 936-950. PMID 32002960 DOI: 10.1016/J.Pharep.2018.04.002  0.621
2018 Wydra K, Suder A, Frankowska M, Borroto Escuela DO, Fuxe K, Filip M. Effects of intra-accumbal or intra-prefrontal cortex microinjections of adenosine 2A receptor ligands on responses to cocaine reward and seeking in rats. Psychopharmacology. 235: 3509-3523. PMID 30426181 DOI: 10.1007/s00213-018-5072-8  0.38
2018 Borroto-Escuela DO, Wydra K, Filip M, Fuxe K. A2AR-D2R Heteroreceptor Complexes in Cocaine Reward and Addiction. Trends in Pharmacological Sciences. 39: 1008-1020. PMID 30384981 DOI: 10.1016/J.Tips.2018.10.007  0.642
2018 Borroto-Escuela DO, Rodriguez D, Romero-Fernandez W, Kapla J, Jaiteh M, Ranganathan A, Lazarova T, Fuxe K, Carlsson J. Mapping the Interface of a GPCR Dimer: A Structural Model of the A Adenosine and D Dopamine Receptor Heteromer. Frontiers in Pharmacology. 9: 829. PMID 30214407 DOI: 10.3389/Fphar.2018.00829  0.638
2018 Imam A, Bhagwandin A, Ajao MS, Ihunwo AO, Fuxe K, Manger PR. The brain of the tree pangolin (Manis tricuspis). III. The unusual locus coeruleus complex. The Journal of Comparative Neurology. PMID 30125941 DOI: 10.1002/Cne.24519  0.303
2018 Borroto-Escuela DO, Tarakanov AO, Brito I, Fuxe K. Glutamate heteroreceptor complexes in the brain. Pharmacological Reports : Pr. 70: 936-950. PMID 30103174 DOI: 10.1016/j.pharep.2018.04.002  0.578
2018 Borroto-Escuela DO, Perez De La Mora M, Manger P, Narváez M, Beggiato S, Crespo-Ramírez M, Navarro G, Wydra K, Díaz-Cabiale Z, Rivera A, Ferraro L, Tanganelli S, Filip M, Franco R, Fuxe K. Brain Dopamine Transmission in Health and Parkinson's Disease: Modulation of Synaptic Transmission and Plasticity Through Volume Transmission and Dopamine Heteroreceptors. Frontiers in Synaptic Neuroscience. 10: 20. PMID 30042672 DOI: 10.3389/Fnsyn.2018.00020  0.815
2018 Kostrzewa RM, Wydra K, Filip M, Crawford C, McDougall SA, Brown RW, Borroto-Escuela DO, Fuxe K, Gainetdinov RR. Dopamine D2 Receptor Supersensitivity as a Spectrum of Neurotoxicity and Status in Psychiatric Disorders. The Journal of Pharmacology and Experimental Therapeutics. PMID 29921706 DOI: 10.1124/Jpet.118.247981  0.524
2018 Borroto-Escuela DO, Narváez M, Ambrogini P, Ferraro L, Brito I, Romero-Fernandez W, Andrade-Talavera Y, Flores-Burgess A, Millon C, Gago B, Narvaez JA, Odagaki Y, Palkovits M, Diaz-Cabiale Z, Fuxe K. Receptor⁻Receptor Interactions in Multiple 5-HT1A Heteroreceptor Complexes in Raphe-Hippocampal 5-HT Transmission and Their Relevance for Depression and Its Treatment. Molecules (Basel, Switzerland). 23. PMID 29865267 DOI: 10.3390/Molecules23061341  0.613
2018 Domenici MR, Chiodi V, Averna M, Armida M, Pèzzola A, Pepponi R, Ferrante A, Bader M, Fuxe K, Popoli P. Neuronal adenosine A receptor overexpression is neuroprotective towards 3-nitropropionic acid-induced striatal toxicity: a rat model of Huntington's disease. Purinergic Signalling. PMID 29770921 DOI: 10.1007/s11302-018-9609-4  0.358
2018 Narváez M, Borroto-Escuela DO, Santín L, Millón C, Gago B, Flores-Burgess A, Barbancho MA, Pérez de la Mora M, Narváez J, Díaz-Cabiale Z, Fuxe K. A Novel Integrative Mechanism in Anxiolytic Behavior Induced by Galanin 2/Neuropeptide Y Y1 Receptor Interactions on Medial Paracapsular Intercalated Amygdala in Rats. Frontiers in Cellular Neuroscience. 12: 119. PMID 29765307 DOI: 10.3389/Fncel.2018.00119  0.802
2018 Valderrama-Carvajal A, Irizar H, Gago B, Jiménez-Urbieta H, Fuxe K, Rodríguez-Oroz MC, Otaegui D, Rivera A. Transcriptomic integration of DR and MOR signaling in the rat caudate putamen. Scientific Reports. 8: 7337. PMID 29743514 DOI: 10.1038/s41598-018-25604-4  0.358
2018 Hinz S, Navarro G, Borroto-Escuela D, Seibt BF, Ammon YC, de Filippo E, Danish A, Lacher SK, Červinková B, Rafehi M, Fuxe K, Schiedel AC, Franco R, Müller CE. Adenosine Areceptor ligand recognition and signaling is blocked by Areceptors. Oncotarget. 9: 13593-13611. PMID 29568380 DOI: 10.18632/Oncotarget.24423  0.613
2018 Borroto-Escuela DO, Hinz S, Navarro G, Franco R, Müller CE, Fuxe K. Understanding the Role of Adenosine A2AR Heteroreceptor Complexes in Neurodegeneration and Neuroinflammation. Frontiers in Neuroscience. 12: 43. PMID 29467608 DOI: 10.3389/Fnins.2018.00043  0.635
2018 Borroto-Escuela DO, Wydra K, Li X, Rodriguez D, Carlsson J, Jastrzębska J, Filip M, Fuxe K. Disruption of A2AR-D2R Heteroreceptor Complexes After A2AR Transmembrane 5 Peptide Administration Enhances Cocaine Self-Administration in Rats. Molecular Neurobiology. PMID 29383683 DOI: 10.1007/S12035-018-0887-1  0.621
2018 Hernández-Pérez OR, Crespo-Ramírez M, Cuza-Ferrer Y, Anias-Calderón J, Zhang L, Roldan-Roldan G, Aguilar-Roblero R, Borroto-Escuela DO, Fuxe K, Perez de la Mora M. Differential activation of arginine-vasopressin receptor subtypes in the amygdaloid modulation of anxiety in the rat by arginine-vasopressin. Psychopharmacology. PMID 29306965 DOI: 10.1007/S00213-017-4817-0  0.79
2017 Millón C, Flores-Burgess A, Castilla-Ortega E, Gago B, García-Fernandez M, Serrano A, Rodriguez de Fonseca F, Narváez JA, Fuxe K, Santín L, Díaz-Cabiale Z. Central administration of galanin N-terminal fragment 1-15 decreases the voluntary alcohol intake in rats. Addiction Biology. PMID 29210146 DOI: 10.1111/adb.12582  0.304
2017 Feltmann K, Borroto-Escuela DO, Rüegg J, Pinton L, de Oliveira Sergio T, Narváez M, Jimenez-Beristain A, Ekström TJ, Fuxe K, Steensland P. Effects of long-term alcohol drinking on the dopamine D2 receptor: Gene expression and heteroreceptor complexes in the striatum in rats. Alcoholism, Clinical and Experimental Research. PMID 29205397 DOI: 10.1111/acer.13568  0.796
2017 Borroto-Escuela DO, DuPont CM, Li X, Savelli D, Lattanzi D, Srivastava I, Narváez M, Di Palma M, Barbieri E, Andrade-Talavera Y, Cuppini R, Odagaki Y, Palkovits M, Ambrogini P, Lindskog M, ... Fuxe K, et al. Disturbances in the FGFR1-5-HT1A Heteroreceptor Complexes in the Raphe-Hippocampal 5-HT System Develop in a Genetic Rat Model of Depression. Frontiers in Cellular Neuroscience. 11: 309. PMID 29066953 DOI: 10.3389/Fncel.2017.00309  0.582
2017 Beggiato S, Borelli AC, Borroto-Escuela D, Corbucci I, Tomasini MC, Marti M, Antonelli T, Tanganelli S, Fuxe K, Ferraro L. Cocaine modulates allosteric D2-σ1 receptor-receptor interactions on dopamine and glutamate nerve terminals from rat striatum. Cellular Signalling. PMID 28923416 DOI: 10.1016/J.Cellsig.2017.09.007  0.65
2017 Borroto-Escuela DO, Li X, Tarakanov AO, Savelli D, Narváez M, Shumilov K, Andrade-Talavera Y, Jimenez-Beristain A, Pomierny B, Díaz-Cabiale Z, Cuppini R, Ambrogini P, Lindskog M, Fuxe K. Existence of Brain 5-HT1A-5-HT2A Isoreceptor Complexes with Antagonistic Allosteric Receptor-Receptor Interactions Regulating 5-HT1A Receptor Recognition. Acs Omega. 2: 4779-4789. PMID 28920103 DOI: 10.1021/acsomega.7b00629  0.579
2017 Navarro G, Borroto-Escuela D, Angelats E, Etayo Í, Reyes-Resina I, Pulido-Salgado M, Rodriguez-Perez AI, Canela EI, Saura J, Lanciego JL, Labandeira-García JL, Saura CA, Fuxe K, Franco R. Receptor-heteromer mediated regulation of endocannabinoid signaling in activated microglia. Role of CB1 and CB2 receptors and relevance for Alzheimer's disease and levodopa-induced dyskinesia. Brain, Behavior, and Immunity. PMID 28843453 DOI: 10.1016/J.Bbi.2017.08.015  0.615
2017 Borroto-Escuela DO, Narváez M, Wydra K, Pintsuk J, Pinton L, Jimenez-Beristain A, Di Palma M, Jastrzębska J, Filip M, Fuxe K. Cocaine self-administration specifically increases A2AR-D2R and D2R-sigma1R heteroreceptor complexes in the rat nucleus accumbens shell. Relevance for cocaine use disorder. Pharmacology, Biochemistry, and Behavior. 155: 24-31. PMID 28300546 DOI: 10.1016/J.Pbb.2017.03.003  0.793
2017 Flores-Burgess A, Millón C, Gago B, Narváez M, Borroto-Escuela DO, Mengod G, Narváez JA, Fuxe K, Santín L, Díaz-Cabiale Z. Galanin (1-15) enhancement of the behavioral effects of Fluoxetine in the forced swimming test gives a new therapeutic strategy against depression. Neuropharmacology. PMID 28288814 DOI: 10.1016/J.Neuropharm.2017.03.010  0.596
2017 Borroto-Escuela DO, Carlsson J, Ambrogini P, Narváez M, Wydra K, Tarakanov AO, Li X, Millón C, Ferraro L, Cuppini R, Tanganelli S, Liu F, Filip M, Diaz-Cabiale Z, Fuxe K. Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease. Frontiers in Cellular Neuroscience. 11: 37. PMID 28270751 DOI: 10.3389/Fncel.2017.00037  0.639
2017 Borroto-Escuela DO, Tarakanov AO, Bechter K, Fuxe K. IL1R2, CCR2, and CXCR4 May Form Heteroreceptor Complexes with NMDAR and D2R: Relevance for Schizophrenia. Frontiers in Psychiatry. 8: 24. PMID 28261115 DOI: 10.3389/Fpsyt.2017.00024  0.635
2017 Millón C, Flores-Burgess A, Narváez M, Borroto-Escuela DO, Gago B, Santín L, Castilla-Ortega E, Narváez JÁ, Fuxe K, Díaz-Cabiale Z. The neuropeptides Galanin and Galanin(1-15) in depression-like behaviours. Neuropeptides. PMID 28196617 DOI: 10.1016/J.Npep.2017.01.004  0.599
2017 Millón C, Flores-Burguess A, Narváez M, Borroto-Escuela D, Santín L, Narváez JA, Fuxe K, Díaz-Cabiale Z. A role for Galanin N-terminal fragment (1-15) In anxiety and depression in rats Neuropeptides. 65: 138-139. DOI: 10.1016/J.Npep.2017.02.036  0.526
2017 Brugal GN, Borroto-Escuela D, Reyes I, Angelats E, Labandeira JL, Fuxe K, Franco R. NEUROPROTECTIVE EFFECT OF CANNABINOID RECEPTORS IN NEUROINFLAMATION Alzheimer's & Dementia. 13: P1505. DOI: 10.1016/J.Jalz.2017.07.616  0.639
2016 Pintsuk J, Borroto-Escuela DO, Lai TK, Liu F, Fuxe K. Alterations in ventral and dorsal striatal allosteric A2AR-D2R receptor-receptor interactions after amphetamine challenge: Relevance for schizophrenia. Life Sciences. PMID 27984074 DOI: 10.1016/J.Lfs.2016.10.027  0.652
2016 Hernández VS, Hernández OR, Perez de la Mora M, Gómora MJ, Fuxe K, Eiden LE, Zhang L. Hypothalamic Vasopressinergic Projections Innervate Central Amygdala GABAergic Neurons: Implications for Anxiety and Stress Coping. Frontiers in Neural Circuits. 10: 92. PMID 27932956 DOI: 10.3389/Fncir.2016.00092  0.739
2016 Cervetto C, Venturini A, Passalacqua M, Guidolin D, Genedani S, Fuxe K, Borroto-Esquela DO, Cortelli P, Woods A, Maura G, Marcoli M, Agnati LF. A2A-D2 receptor-receptor interaction modulates gliotransmitter release from striatal astrocyte processes. Journal of Neurochemistry. PMID 27896809 DOI: 10.1111/Jnc.13885  0.452
2016 Borroto-Escuela DO, Wydra K, Pintsuk J, Narvaez M, Corrales F, Zaniewska M, Agnati LF, Franco R, Tanganelli S, Ferraro L, Filip M, Fuxe K. Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disorder: A Role for Allosteric Receptor-Receptor Interactions in A2A-D2 Heteroreceptor Complexes. Neural Plasticity. 2016: 4827268. PMID 27872762 DOI: 10.1155/2016/4827268  0.64
2016 Borroto-Escuela DO, Fuxe K. Diversity and bias through dopamine D2R heteroreceptor complexes. Current Opinion in Pharmacology. 32: 16-22. PMID 27838588 DOI: 10.1016/J.Coph.2016.10.004  0.651
2016 Di Liberto V, Borroto-Escuela DO, Frinchi M, Verdi V, Fuxe K, Belluardo N, Mudò G. Existence of muscarinic acetylcholine receptor (mAChR) and fibroblast growth factor receptor (FGFR) heteroreceptor complexes and their enhancement of neurite outgrowth in neural hippocampal cultures. Biochimica Et Biophysica Acta. General Subjects. 1861: 235-245. PMID 27815219 DOI: 10.1016/j.bbagen.2016.10.026  0.639
2016 Fuxe K, Borroto-Escuela DO. Volume transmission and receptor-receptor interactions in heteroreceptor complexes: understanding the role of new concepts for brain communication. Neural Regeneration Research. 11: 1220-3. PMID 27651759 DOI: 10.4103/1673-5374.189168  0.61
2016 de la Mora MP, Pérez-Carrera D, Crespo-Ramírez M, Tarakanov A, Fuxe K, Borroto-Escuela DO. Signaling in dopamine D2 receptor-Oxytocin receptor heterocomplexes and its relevance for the anxiolytic effects of dopamine and oxytocin interactions in the amygdala of the rat. Biochimica Et Biophysica Acta. PMID 27425032 DOI: 10.1016/J.Bbadis.2016.07.004  0.654
2016 Rebolledo-Solleiro D, Araiza LF, Broccoli L, Hansson AC, Rocha-Arrieta LL, Aguilar-Roblero R, Crespo-Ramírez M, Fuxe K, Pérez de la Mora M. Dopamine D1 receptor activity is involved in the increased anxiety levels observed in STZ-induced diabetes in rats. Behavioural Brain Research. PMID 27374159 DOI: 10.1016/J.Bbr.2016.06.060  0.749
2016 Rivera A, Gago B, Suárez-Boomgaard D, Yoshitake T, Roales-Buján R, Valderrama-Carvajal A, Bilbao A, Medina-Luque J, Díaz-Cabiale Z, Craenenbroeck KV, Borroto-Escuela DO, Kehr J, Rodríguez de Fonseca F, Santín L, de la Calle A, ... Fuxe K, et al. Dopamine D4 receptor stimulation prevents nigrostriatal dopamine pathway activation by morphine: relevance for drug addiction. Addiction Biology. PMID 27212105 DOI: 10.1111/Adb.12407  0.632
2016 Skieterska K, Shen A, Clarisse D, Rondou P, Borroto-Escuela DO, Lintermans B, Fuxe K, Xiang YK, Van Craenenbroeck K. Characterization of the interaction between the dopamine D4 receptor, KLHL12 and β-arrestins. Cellular Signalling. PMID 27155323 DOI: 10.1016/J.Cellsig.2016.05.003  0.641
2016 Borroto-Escuela DO, Pintsuk J, Schäfer T, Friedland K, Ferraro L, Tanganelli S, Liu F, Fuxe K. Multiple D2 heteroreceptor complexes: new targets for treatment of schizophrenia. Therapeutic Advances in Psychopharmacology. 6: 77-94. PMID 27141290 DOI: 10.1177/2045125316637570  0.642
2016 Beggiato S, Tomasini MC, Borelli AC, Borroto-Escuela DO, Fuxe K, Antonelli T, Tanganelli S, Ferraro L. Functional role of striatal A2A, D2 and mGlu5 receptor interactions in regulating striatopallidal GABA neuron transmission. Journal of Neurochemistry. PMID 27127992 DOI: 10.1111/Jnc.13652  0.63
2016 Pintsuk J, Borroto-Escuela DO, Pomierny B, Wydra K, Zaniewska M, Filip M, Fuxe K. Cocaine self-administration differentially affects allosteric A2A-D2 receptor-receptor interactions in the striatum. Relevance for cocaine use disorder. Pharmacology, Biochemistry, and Behavior. PMID 26987369 DOI: 10.1016/J.Pbb.2016.03.004  0.626
2016 Sahlholm K, Zeberg H, Nilsson J, Ögren SO, Fuxe K, Århem P. The fast-off hypothesis revisited: A functional kinetic study of antipsychotic antagonism of the dopamine D2 receptor. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26811292 DOI: 10.1016/J.Euroneuro.2016.01.001  0.392
2016 Millón C, Flores-Burgess A, Narváez M, Borroto-Escuela DO, Santín L, Gago B, Narváez JA, Fuxe K, Díaz-Cabiale Z. Galanin (1-15) enhances the antidepressant effects of the 5-HT1A receptor agonist 8-OH-DPAT: involvement of the raphe-hippocampal 5-HT neuron system. Brain Structure & Function. PMID 26792005 DOI: 10.1007/S00429-015-1180-Y  0.641
2016 Fuxe K, Borroto-Escuela DO. Heteroreceptor Complexes and their Allosteric Receptor-Receptor Interactions as a Novel Biological Principle for Integration of Communication in the CNS: Targets for Drug Development. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 41: 380-2. PMID 26657959 DOI: 10.1038/Npp.2015.244  0.581
2016 Borroto-Escuela DO, Narváez M, Mudó G, Palma Md, Savelli D, Sartini S, Agnati LF, Ambrogini P, Cuppini R, Belluardo N, Fuxe K. Speaker 4: Dasiel Borroto – Escuela, Sweden The International Journal of Neuropsychopharmacology. 19: 34-34. DOI: 10.1093/Ijnp/Pyw042.087  0.491
2016 Narváez M, Millón C, Borroto-Escuela D, Flores-Burgess A, Santín L, Fuxe K, Narváez JA, Díaz-Cabiale Z. Galanin receptor 2/neuropeptide Y Y1 receptor interactions in the amygdala of the rat Neuropeptides. 55: 19. DOI: 10.1016/J.Npep.2015.11.052  0.639
2016 Borroto-Escuela DO, Hagman B, Woolfenden M, Pinton L, Jiménez-Beristain A, Oflijan J, Narvaez M, Di Palma M, Feltmann K, Sartini S, Ambrogini P, Ciruela F, Cuppini R, Fuxe K. In situ proximity ligation assay to study and understand the distribution and balance of GPCR homo- and heteroreceptor complexes in the brain Neuromethods. 110: 109-124. DOI: 10.1007/978-1-4939-3064-7_9  0.487
2016 Morató X, Borroto-Escuela DO, Fuxe K, Fernández-Dueñas V, Ciruela F. Co-immunoprecipitation from brain Neuromethods. 110: 19-29. DOI: 10.1007/978-1-4939-3064-7_2  0.462
2015 Borroto-Escuela DO, Tarakanov AO, Fuxe K. FGFR1-5-HT1A Heteroreceptor Complexes: Implications for Understanding and Treating Major Depression. Trends in Neurosciences. PMID 26687454 DOI: 10.1016/J.Tins.2015.11.003  0.64
2015 Narváez M, Borroto-Escuela DO, Millón C, Gago B, Flores-Burgess A, Santín L, Fuxe K, Narváez JA, Díaz-Cabiale Z. Galanin receptor 2-neuropeptide Y Y1 receptor interactions in the dentate gyrus are related with antidepressant-like effects. Brain Structure & Function. PMID 26666529 DOI: 10.1007/S00429-015-1153-1  0.626
2015 Chiodi V, Ferrante A, Ferraro L, Potenza RL, Armida M, Beggiato S, Pèzzola A, Bader M, Fuxe K, Popoli P, Domenici MR. Striatal adenosine-cannabinoid receptor interactions in rats overexpressing adenosine A2A receptors. Journal of Neurochemistry. PMID 26526685 DOI: 10.1111/jnc.13421  0.431
2015 Agnati LF, Guidolin D, Cervetto C, Borroto-Escuela DO, Fuxe K. Role of iso-receptors in receptor-receptor interactions with a focus on dopamine iso-receptor complexes. Reviews in the Neurosciences. PMID 26418645 DOI: 10.1515/Revneuro-2015-0024  0.654
2015 Tena-Campos M, Ramon E, Borroto-Escuela DO, Fuxe K, Garriga P. The zinc binding receptor GPR39 interacts with 5-HT1A and GalR1 to form dynamic heteroreceptor complexes with signaling diversity. Biochimica Et Biophysica Acta. 1852: 2585-2592. PMID 26365466 DOI: 10.1016/J.Bbadis.2015.09.003  0.646
2015 Fuxe K, Borroto-Escuela DO. Basimglurant for treatment of major depressive disorder: a novel negative allosteric modulator of metabotropic glutamate receptor 5. Expert Opinion On Investigational Drugs. 24: 1247-60. PMID 26219727 DOI: 10.1517/13543784.2015.1074175  0.578
2015 Navarro G, Borroto-Escuela DO, Fuxe K, Franco R. Purinergic signaling in Parkinson's disease. Relevance for treatment. Neuropharmacology. PMID 26211977 DOI: 10.1016/J.Neuropharm.2015.07.024  0.635
2015 Tarakanov AO, Fuxe K. The triplet puzzle theory indicates extensive formation of heteromers between opioid and chemokine receptor subtypes. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 26133164 DOI: 10.1007/s00702-015-1421-5  0.373
2015 Borroto-Escuela DO, Agnati LF, Bechter K, Jansson A, Tarakanov AO, Fuxe K. The role of transmitter diffusion and flow versus extracellular vesicles in volume transmission in the brain neural-glial networks. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 370. PMID 26009762 DOI: 10.1098/Rstb.2014.0183  0.628
2015 Borroto-Escuela DO, Pérez-Alea M, Narvaez M, Tarakanov AO, Mudó G, Jiménez-Beristain A, Agnati LF, Ciruela F, Belluardo N, Fuxe K. Enhancement of the FGFR1 signaling in the FGFR1-5-HT1A heteroreceptor complex in midbrain raphe 5-HT neuron systems. Relevance for neuroplasticity and depression. Biochemical and Biophysical Research Communications. 463: 180-6. PMID 25957476 DOI: 10.1016/J.Bbrc.2015.04.133  0.619
2015 Fuxe K, Agnati LF, Marcoli M, Borroto-Escuela DO. Volume Transmission in Central Dopamine and Noradrenaline Neurons and Its Astroglial Targets. Neurochemical Research. PMID 25894681 DOI: 10.1007/S11064-015-1574-5  0.634
2015 Leo G, Guescini M, Genedani S, Stocchi V, Carone C, Filaferro M, Sisti D, Marcoli M, Maura G, Cortelli P, Guidolin D, Fuxe K, Agnati LF. Acute isoproterenol induces anxiety-like behavior in rats and increases plasma content of extracellular vesicles. Physiology & Behavior. 142: 79-84. PMID 25654993 DOI: 10.1016/j.physbeh.2015.02.002  0.352
2015 Millón C, Flores-Burgess A, Narváez M, Borroto-Escuela DO, Santín L, Parrado C, Narváez JA, Fuxe K, Díaz-Cabiale Z. A role for galanin N-terminal fragment (1-15) in anxiety- and depression-related behaviors in rats. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25522404 DOI: 10.1093/Ijnp/Pyu064  0.622
2015 Fuxe K, Guidolin D, Agnati LF, Borroto-Escuela DO. Dopamine heteroreceptor complexes as therapeutic targets in Parkinson's disease. Expert Opinion On Therapeutic Targets. 19: 377-98. PMID 25486101 DOI: 10.1517/14728222.2014.981529  0.607
2015 Borroto-Escuela DO, Narvaez M, Pérez-Alea M, Tarakanov AO, Jiménez-Beristain A, Mudó G, Agnati LF, Ciruela F, Belluardo N, Fuxe K. Evidence for the existence of FGFR1-5-HT1A heteroreceptor complexes in the midbrain raphe 5-HT system. Biochemical and Biophysical Research Communications. 456: 489-93. PMID 25485703 DOI: 10.1016/J.Bbrc.2014.11.112  0.597
2015 Wydra K, Suder A, Borroto-Escuela DO, Filip M, Fuxe K. On the role of A₂A and D₂ receptors in control of cocaine and food-seeking behaviors in rats. Psychopharmacology. 232: 1767-78. PMID 25420611 DOI: 10.1007/S00213-014-3818-5  0.618
2015 Guidolin D, Agnati LF, Marcoli M, Borroto-Escuela DO, Fuxe K. G-protein-coupled receptor type A heteromers as an emerging therapeutic target. Expert Opinion On Therapeutic Targets. 19: 265-83. PMID 25381716 DOI: 10.1517/14728222.2014.981155  0.613
2015 Wydra K, Go?embiowska K, Suder A, Kami?ska K, Fuxe K, Filip M. On the role of adenosine (A)₂A receptors in cocaine-induced reward: a pharmacological and neurochemical analysis in rats. Psychopharmacology. 232: 421-35. PMID 25027583 DOI: 10.1007/s00213-014-3675-2  0.38
2015 Narváez M, Millón C, Borroto-Escuela D, Flores-Burgess A, Santín L, Parrado C, Gago B, Puigcerver A, Fuxe K, Narváez JA, Díaz-Cabiale Z. Galanin receptor 2-neuropeptide Y Y1 receptor interactions in the amygdala lead to increased anxiolytic actions. Brain Structure & Function. 220: 2289-301. PMID 24841617 DOI: 10.1007/S00429-014-0788-7  0.638
2015 Borroto-Escuela DO, Narvaez M, Jiménez-Beristain A, Oflijan J, Pinton L, Di Palma M, Tarakanov AO, Mudó G, Agnati LF, Belluardo N, Fuxe K. Increase of the FGFR1 signaling in the FGFR1-5-HT1A heteroreceptor complex in midbrain raphe 5-HT neuron systems via allosteric receptor-receptor interaction Springerplus. 4. DOI: 10.1186/2193-1801-4-S1-P4  0.624
2015 Pinton L, Borroto-Escuela DO, Narváez M, Oflijan J, Agnati LF, Fuxe K. Evidence for the existence of dopamine D2R and Sigma 1 allosteric receptor-receptor interaction in the rat brain: role in brain plasticity and cocaine action Springerplus. 4: 37. DOI: 10.1186/2193-1801-4-S1-P37  0.642
2015 Oflijan J, Borroto-Escuela D, Woolfenden M, Palma MD, Pinton L, Brito I, Narváez M, Corales F, Jimenez-Beristein A, Agnati LF, Fuxe K. Evidence for the existence of the A2A-A1 heteroreceptor complex in the rat brain, and comparison of its distribution to that of the A2A-A2A homoreceptor complex Springerplus. 4. DOI: 10.1186/2193-1801-4-S1-P31  0.619
2015 Fuxe K, Hansson A, Borroto-Escuela DO. Sy28-5Receptor-Receptor Interactions In Heteroreceptor Complexes. A New Concept In Neuropsychopharmacology Alcohol and Alcoholism. 50. DOI: 10.1093/Alcalc/Agv076.117  0.634
2015 Broccoli L, Jüngling K, Borroto-Escuela DO, Spanagel R, Sommer WH, Pape HC, Fuxe K, Deussing JM, Hansson AC. SY28-4CROSS-TALK OF CORTICOTROPIN RELEASING HORMONE RECEPTOR SUBTYPE 1 WITH DOPAMINE D1 RECEPTOR: FUNCTIONAL RELEVANCE IN ALCOHOL DEPENDENCE Alcohol and Alcoholism. 50: i31.4-i31. DOI: 10.1093/Alcalc/Agv076.116  0.585
2015 Borroto-Escuela DO, Oflijan J, Pinton L, Wydra K, Narváez M, Hansson A, Ferraro L, Filip M, Fuxe K. SY28FUNCTIONAL RELEVANCE FOR RECEPTOR-RECEPTOR INTERACTION IN STRESS AND ADDICTION RELATED PROCESSES: NEW CONCEPTS IN NEUROPSYCHOPHARMACOLOGYSY28-1ADENOSINE A2A-DOPAMINE D2 HETERORECEPTOR COMPLEXES IN THE BRAIN: RELEVANCE FOR COCAINE ADDICTION Alcohol and Alcoholism. 50: i31.1-i31. DOI: 10.1093/Alcalc/Agv076.113  0.647
2015 Pinton L, Borroto-Escuela D, Narvaez M, Jimenez-Beristein A, Oflijan J, Ferraro L, Agnati L, Fuxe K. P.6.c.001 Dopamine D2 receptor dynamic and modulation in the D2R-Sigma 1 heteroreceptor complexes: role in cocaine action European Neuropsychopharmacology. 25: S609-S610. DOI: 10.1016/S0924-977X(15)30860-9  0.624
2015 Fuxe K, Tarakanov A, Ferraro L, Agnati L, Filip M, Tanganelli S, Borroto-Escuela D. E.07.01 Multiple D2 heteroreceptor complexes in the ventral striatum modulating the brain circuit to the prefrontal cortex – a new target for treatment of schizophrenia European Neuropsychopharmacology. 25. DOI: 10.1016/S0924-977X(15)30134-6  0.552
2015 Fuxe K, Gago B, Suarez-Boomgaard D, Narvaez M, Agnati LF, Skieterska K, Van Craenenbroeck K, Rivera A, Borroto-Escuela DO. Heteroreceptor Complexes in the Central Nervous System. Focus on Their Role in Pain Modulation Journal of Acupuncture and Meridian Studies. 8: 334-335. DOI: 10.1016/J.Jams.2015.11.030  0.519
2014 Navarro G, Borroto-Escuela DO, Fuxe K, Franco R. Potential of caveolae in the therapy of cardiovascular and neurological diseases. Frontiers in Physiology. 5: 370. PMID 25324780 DOI: 10.3389/Fphys.2014.00370  0.597
2014 Romero-Fernandez W, Borroto-Escuela DO, Vargas-Barroso V, Narváez M, Di Palma M, Agnati LF, Larriva Sahd J, Fuxe K. Dopamine D1 and D2 receptor immunoreactivities in the arcuate-median eminence complex and their link to the tubero-infundibular dopamine neurons. European Journal of Histochemistry : Ejh. 58: 2400. PMID 25308843 DOI: 10.4081/Ejh.2014.2400  0.663
2014 Fuxe K, Borroto-Escuela D, Fisone G, Agnati LF, Tanganelli S. Understanding the role of heteroreceptor complexes in the central nervous system. Current Protein & Peptide Science. 15: 647. PMID 25256022 DOI: 10.2174/138920371507140916122738  0.665
2014 Tena-Campos M, Ramon E, Rivera D, Borroto-Escuela DO, Romero-Fernandez W, Fuxe K, Garriga P. G-protein-coupled receptors oligomerization: emerging signaling units and new opportunities for drug design. Current Protein & Peptide Science. 15: 648-58. PMID 25175459 DOI: 10.2174/1389203715666140901094248  0.609
2014 Beggiato S, Antonelli T, Tomasini MC, Borelli AC, Agnati LF, Tanganelli S, Fuxe K, Ferraro L. Adenosine A2A-D2 receptor-receptor interactions in putative heteromers in the regulation of the striato-pallidal gaba pathway: possible relevance for parkinson's disease and its treatment. Current Protein & Peptide Science. 15: 673-80. PMID 25175458 DOI: 10.2174/1389203715666140901103205  0.471
2014 Ferraro L, Beggiato S, Borroto-Escuela DO, Ravani L, O'Connor WT, Tomasini MC, Borelli AC, Agnati LF, Antonelli T, Tanganelli S, Fuxe K. Neurotensin NTS1-dopamine D2 receptor-receptor interactions in putative receptor heteromers: relevance for Parkinson's disease and schizophrenia. Current Protein & Peptide Science. 15: 681-90. PMID 25175457 DOI: 10.2174/1389203715666140901105253  0.654
2014 Van Craenenbroeck K, Borroto-Escuela DO, Skieterska K, Duchou J, Romero-Fernandez W, Fuxe K. Role of dimerization in dopamine D(4) receptor biogenesis. Current Protein & Peptide Science. 15: 659-65. PMID 25175456 DOI: 10.2174/1389203715666140901110256  0.623
2014 Díaz-Cabiale Z, Flores-Burgess A, Parrado C, Narváez M, Millón C, Puigcerver A, Coveñas R, Fuxe K, Narváez JA. Galanin receptor/neuropeptide y receptor interactions in the central nervous system. Current Protein & Peptide Science. 15: 666-72. PMID 25175455 DOI: 10.2174/1389203715666140901111709  0.437
2014 Di Liberto V, Mudo G, Fuxe K, Belluardo N. Interactions between cholinergic and fibroblast growth factor receptors in brain trophism and plasticity. Current Protein & Peptide Science. 15: 691-702. PMID 25175454 DOI: 10.2174/1389203715666140901112245  0.409
2014 Agnati LF, Guidolin D, Marcoli M, Genedani S, Borroto-Escuela D, Maura G, Fuxe K. "Neuro-semeiotics" and "free-energy minimization" suggest a unified perspective for integrative brain actions: focus on receptor heteromers and Roamer type of volume transmission. Current Protein & Peptide Science. 15: 703-18. PMID 25175453 DOI: 10.2174/1389203715666140901112725  0.573
2014 Borroto-Escuela DO, Narvaez M, Di Palma M, Calvo F, Rodriguez D, Millon C, Carlsson J, Agnati LF, Garriga P, Díaz-Cabiale Z, Fuxe K. Preferential activation by galanin 1-15 fragment of the GalR1 protomer of a GalR1-GalR2 heteroreceptor complex. Biochemical and Biophysical Research Communications. 452: 347-53. PMID 25152404 DOI: 10.1016/J.Bbrc.2014.08.061  0.61
2014 Patzke N, Bertelsen MF, Fuxe K, Manger PR. Nuclear organization of cholinergic, catecholaminergic, serotonergic and orexinergic systems in the brain of the Tasmanian devil (Sarcophilus harrisii). Journal of Chemical Neuroanatomy. 61: 94-106. PMID 25150966 DOI: 10.1016/J.Jchemneu.2014.08.005  0.303
2014 Agnati LF, Fuxe K. Extracellular-vesicle type of volume transmission and tunnelling-nanotube type of wiring transmission add a new dimension to brain neuro-glial networks. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369. PMID 25135966 DOI: 10.1098/rstb.2013.0505  0.302
2014 Fuxe K, Borroto-Escuela DO, Tarakanov AO, Romero-Fernandez W, Ferraro L, Tanganelli S, Perez-Alea M, Di Palma M, Agnati LF. Dopamine D2 heteroreceptor complexes and their receptor-receptor interactions in ventral striatum: novel targets for antipsychotic drugs. Progress in Brain Research. 211: 113-39. PMID 24968778 DOI: 10.1016/B978-0-444-63425-2.00005-2  0.638
2014 Fuxe K, Agnati LF, Borroto-Escuela DO. The impact of receptor-receptor interactions in heteroreceptor complexes on brain plasticity. Expert Review of Neurotherapeutics. 14: 719-21. PMID 24894440 DOI: 10.1586/14737175.2014.922878  0.641
2014 Agnati LF, Guidolin D, Maura G, Marcoli M, Leo G, Carone C, De Caro R, Genedani S, Borroto-Escuela DO, Fuxe K. Information handling by the brain: proposal of a new "paradigm" involving the roamer type of volume transmission and the tunneling nanotube type of wiring transmission. Journal of Neural Transmission (Vienna, Austria : 1996). 121: 1431-49. PMID 24866694 DOI: 10.1007/S00702-014-1240-0  0.555
2014 Fuxe K, Tarakanov A, Romero Fernandez W, Ferraro L, Tanganelli S, Filip M, Agnati LF, Garriga P, Diaz-Cabiale Z, Borroto-Escuela DO. Diversity and Bias through Receptor-Receptor Interactions in GPCR Heteroreceptor Complexes. Focus on Examples from Dopamine D2 Receptor Heteromerization. Frontiers in Endocrinology. 5: 71. PMID 24860548 DOI: 10.3389/Fendo.2014.00071  0.671
2014 Borroto-Escuela DO, Brito I, Romero-Fernandez W, Di Palma M, Oflijan J, Skieterska K, Duchou J, Van Craenenbroeck K, Suárez-Boomgaard D, Rivera A, Guidolin D, Agnati LF, Fuxe K. The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components. International Journal of Molecular Sciences. 15: 8570-90. PMID 24830558 DOI: 10.3390/Ijms15058570  0.569
2014 JastrzÄ™bska J, Nowak E, Smaga I, Bystrowska B, Frankowska M, Bader M, Filip M, Fuxe K. Adenosine (A)(2A)receptor modulation of nicotine-induced locomotor sensitization. A pharmacological and transgenic approach. Neuropharmacology. 81: 318-26. PMID 24632528 DOI: 10.1016/j.neuropharm.2014.03.002  0.398
2014 Beggiato S, Tanganelli S, Fuxe K, Antonelli T, Schwarcz R, Ferraro L. Endogenous kynurenic acid regulates extracellular GABA levels in the rat prefrontal cortex. Neuropharmacology. 82: 11-8. PMID 24607890 DOI: 10.1016/j.neuropharm.2014.02.019  0.397
2014 Suárez-Boomgaard D, Gago B, Valderrama-Carvajal A, Roales-Buján R, Craenenbroeck KV, Duchou J, Borroto-Escuela DO, Medina-Luque J, de la Calle A, Fuxe K, Rivera A. Dopamine Dâ‚„ receptor counteracts morphine-induced changes in µ opioid receptor signaling in the striosomes of the rat caudate putamen. International Journal of Molecular Sciences. 15: 1481-98. PMID 24451133 DOI: 10.3390/Ijms15011481  0.628
2014 Borroto-Escuela DO, Romero-Fernandez W, Narvaez M, Oflijan J, Agnati LF, Fuxe K. Hallucinogenic 5-HT2AR agonists LSD and DOI enhance dopamine D2R protomer recognition and signaling of D2-5-HT2A heteroreceptor complexes. Biochemical and Biophysical Research Communications. 443: 278-84. PMID 24309097 DOI: 10.1016/J.Bbrc.2013.11.104  0.672
2014 Fuxe K, Borroto-Escuela DO, Romero-Fernandez W, Palkovits M, Tarakanov AO, Ciruela F, Agnati LF. Moonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 131-55. PMID 24105074 DOI: 10.1038/Npp.2013.242  0.628
2014 Sahlholm K, Marcellino D, Nilsson J, Ögren SO, Fuxe K, Ã…rhem P. Typical and atypical antipsychotics do not differ markedly in their reversibility of antagonism of the dopamine D2 receptor. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 149-55. PMID 24074141 DOI: 10.1017/S1461145713000801  0.715
2014 Sahlholm K, Zeberg H, Marcellino D, Nilsson J, Ogren S, Fuxe K, Arhem P. P.3.c.010 The fast-off hypothesis revisited: on-rates and reversibility of antipsychotic antagonism at the D2 receptor European Neuropsychopharmacology. 24: S520. DOI: 10.1016/S0924-977X(14)70833-8  0.362
2014 Escuela DOB, Calvo F, Narvaez M, Romero-Fernandez W, Millon C, Palma MD, Pérez-Alea M, Tena M, Agnati LF, Tarakanov AO, Garriga P, Díaz-Cabiale Z, Fuxe K. P.1.g.067 The GalR1–GalR2 heteroreceptor complex can be the receptor for galanin fragment 1–15 European Neuropsychopharmacology. 24. DOI: 10.1016/S0924-977X(14)70378-5  0.333
2014 Fuxe K, Borroto-Escuela D, Guidolin D, Tarakanov A, Agnati L. The balance and integration of different forms of volume and wiring transmission in the CNS. Relevance for schizophrenia Neurology, Psychiatry and Brain Research. 20: 11-12. DOI: 10.1016/J.Npbr.2014.01.150  0.509
2014 Borroto-Escuela DO, Romero-Fernandez W, Brito I, Tarakanov AO, Guidolin D, Agnati LF, Fuxe K. The receptor–receptor interactions within the cytokine receptor superfamily. Role in neuroinflammation and beyond Neurology Psychiatry and Brain Research. 20: 6-7. DOI: 10.1016/J.Npbr.2014.01.141  0.613
2014 Ferraro L, Beggiato S, Borroto-Escuela DO, Ravani L, O'connor WT, Tomasini MC, Borelli AC, Agnati LF, Antonelli T, Tanganelli S, Fuxe K. Neurotensin nts1-dopamine d2 receptor-receptor interactions in putative receptor heteromers: Relevance for parkinson’s disease and schizophrenia Current Protein and Peptide Science. 15: 703-718.  0.614
2013 Borroto-Escuela DO, Corrales F, Narvaez M, Oflijan J, Agnati LF, Palkovits M, Fuxe K. Dynamic modulation of FGFR1-5-HT1A heteroreceptor complexes. Agonist treatment enhances participation of FGFR1 and 5-HT1A homodimers and recruitment of β-arrestin2. Biochemical and Biophysical Research Communications. 441: 387-92. PMID 24157794 DOI: 10.1016/J.Bbrc.2013.10.067  0.616
2013 Borroto-Escuela DO, Flajolet M, Agnati LF, Greengard P, Fuxe K. Bioluminescence resonance energy transfer methods to study G protein-coupled receptor-receptor tyrosine kinase heteroreceptor complexes. Methods in Cell Biology. 117: 141-64. PMID 24143976 DOI: 10.1016/B978-0-12-408143-7.00008-6  0.623
2013 Gago B, Fuxe K, Brené S, Díaz-Cabiale Z, Reina-Sánchez MD, Suárez-Boomgaard D, Roales-Buján R, Valderrama-Carvajal A, de la Calle A, Rivera A. Early modulation by the dopamine D4 receptor of morphine-induced changes in the opioid peptide systems in the rat caudate putamen. Journal of Neuroscience Research. 91: 1533-40. PMID 24038231 DOI: 10.1002/jnr.23277  0.356
2013 Maseko BC, Patzke N, Fuxe K, Manger PR. Architectural organization of the african elephant diencephalon and brainstem. Brain, Behavior and Evolution. 82: 83-128. PMID 24021932 DOI: 10.1159/000352004  0.312
2013 Borroto-Escuela DO, Romero-Fernandez W, Rivera A, Van Craenenbroeck K, Tarakanov AO, Agnati LF, Fuxe K. On the g-protein-coupled receptor heteromers and their allosteric receptor-receptor interactions in the central nervous system: focus on their role in pain modulation. Evidence-Based Complementary and Alternative Medicine : Ecam. 2013: 563716. PMID 23956775 DOI: 10.1155/2013/563716  0.613
2013 Fuxe K, Borroto-Escuela DO, Romero-Fernandez W, Zhang WB, Agnati LF. Volume transmission and its different forms in the central nervous system. Chinese Journal of Integrative Medicine. 19: 323-9. PMID 23674109 DOI: 10.1007/S11655-013-1455-1  0.592
2013 Borroto-Escuela DO, Ravani A, Tarakanov AO, Brito I, Narvaez M, Romero-Fernandez W, Corrales F, Agnati LF, Tanganelli S, Ferraro L, Fuxe K. Dopamine D2 receptor signaling dynamics of dopamine D2-neurotensin 1 receptor heteromers. Biochemical and Biophysical Research Communications. 435: 140-6. PMID 23624386 DOI: 10.1016/J.Bbrc.2013.04.058  0.675
2013 Beggiato S, Antonelli T, Tomasini MC, Tanganelli S, Fuxe K, Schwarcz R, Ferraro L. Kynurenic acid, by targeting α7 nicotinic acetylcholine receptors, modulates extracellular GABA levels in the rat striatum in vivo. The European Journal of Neuroscience. 37: 1470-7. PMID 23442092 DOI: 10.1111/ejn.12160  0.378
2013 Borroto-Escuela DO, Romero-Fernandez W, Garriga P, Ciruela F, Narvaez M, Tarakanov AO, Palkovits M, Agnati LF, Fuxe K. G protein-coupled receptor heterodimerization in the brain. Methods in Enzymology. 521: 281-94. PMID 23351745 DOI: 10.1016/B978-0-12-391862-8.00015-6  0.608
2013 Wydra K, Golembiowska K, Zaniewska M, KamiÅ„ska K, Ferraro L, Fuxe K, Filip M. Accumbal and pallidal dopamine, glutamate and GABA overflow during cocaine self-administration and its extinction in rats. Addiction Biology. 18: 307-24. PMID 23311632 DOI: 10.1111/adb.12031  0.32
2013 Romero-Fernandez W, Borroto-Escuela DO, Agnati LF, Fuxe K. Evidence for the existence of dopamine D2-oxytocin receptor heteromers in the ventral and dorsal striatum with facilitatory receptor-receptor interactions. Molecular Psychiatry. 18: 849-50. PMID 22824810 DOI: 10.1038/Mp.2012.103  0.676
2013 Frankowska M, Marcellino D, Adamczyk P, Filip M, Fuxe K. Effects of cocaine self-administration and extinction on D2 -like and A2A receptor recognition and D2 -like/Gi protein coupling in rat striatum. Addiction Biology. 18: 455-66. PMID 22500978 DOI: 10.1111/j.1369-1600.2012.00452.x  0.698
2013 Sahlholm K, Ã…rhem P, Fuxe K, Marcellino D. The dopamine stabilizers ACR16 and (-)-OSU6162 display nanomolar affinities at the σ-1 receptor. Molecular Psychiatry. 18: 12-4. PMID 22349783 DOI: 10.1038/Mp.2012.3  0.428
2013 Fuxe K, Borroto-Escuela DO, Tarakanov A, Fernandez WR, Manger P, Rivera A, Van Craenenbroeck K, Skieterska K, Diaz-Cabiale Z, Filip M, Ferraro L, Tanganelli S, Guidolin D, Cullheim S, De La Mora MP, et al. Understanding the balance and integration of volume and synaptic transmission. Relevance for psychiatry Neurology Psychiatry and Brain Research. 19: 141-158. DOI: 10.1016/J.Npbr.2013.10.002  0.603
2013 Sahlholm K, Frisk S, Nilsson J, Marcellino D, Fuxe K, Ove Ögren S, Århem P. Novel Aspects of the Reversibility of the Antagonism at the Dopamine D2 Receptor by Antipsychotics Biophysical Journal. 104: 26a. DOI: 10.1016/J.Bpj.2012.11.183  0.422
2012 Fuxe K, Borroto-Escuela DO, Romero-Fernandez W, Tarakanov AO, Calvo F, Garriga P, Tena M, Narvaez M, Millón C, Parrado C, Ciruela F, Agnati LF, Narvaez JA, Díaz-Cabiale Z. On the existence and function of galanin receptor heteromers in the central nervous system. Frontiers in Endocrinology. 3: 127. PMID 23112793 DOI: 10.3389/Fendo.2012.00127  0.668
2012 Marcellino D, Frankowska M, Agnati L, Perez de la Mora M, Vargas-Barroso V, Fuxe K, Larriva-Sahd J. Intercalated and paracapsular cell islands of the adult rat amygdala: a combined rapid-Golgi, ultrastructural, and immunohistochemical account. Neuroscience. 226: 324-47. PMID 22986165 DOI: 10.1016/j.neuroscience.2012.08.067  0.75
2012 Fernández-Dueñas V, Gómez-Soler M, Jacobson KA, Kumar ST, Fuxe K, Borroto-Escuela DO, Ciruela F. Molecular determinants of A2AR-D2R allosterism: role of the intracellular loop 3 of the D2R. Journal of Neurochemistry. 123: 373-84. PMID 22924752 DOI: 10.1111/J.1471-4159.2012.07956.X  0.606
2012 Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P. Voltage sensitivities and deactivation kinetics of histamine H₃ and Hâ‚„ receptors. Biochimica Et Biophysica Acta. 1818: 3081-9. PMID 22885137 DOI: 10.1016/J.Bbamem.2012.07.027  0.722
2012 Tarakanov AO, Fuxe KG, Borroto-Escuela DO. Integrin triplets of marine sponges in human D2 receptor heteromers. Journal of Receptor and Signal Transduction Research. 32: 202-8. PMID 22712841 DOI: 10.3109/10799893.2012.692119  0.614
2012 Fernández-Dueñas V, Llorente J, Gandía J, Borroto-Escuela DO, Agnati LF, Tasca CI, Fuxe K, Ciruela F. Fluorescence resonance energy transfer-based technologies in the study of protein-protein interactions at the cell surface. Methods (San Diego, Calif.). 57: 467-72. PMID 22683304 DOI: 10.1016/J.Ymeth.2012.05.007  0.525
2012 Fuxe K, Borroto-Escuela DO, Romero-Fernandez W, Diaz-Cabiale Z, Rivera A, Ferraro L, Tanganelli S, Tarakanov AO, Garriga P, Narváez JA, Ciruela F, Guescini M, Agnati LF. Extrasynaptic neurotransmission in the modulation of brain function. Focus on the striatal neuronal-glial networks. Frontiers in Physiology. 3: 136. PMID 22675301 DOI: 10.3389/Fphys.2012.00136  0.644
2012 Agnati LF, Guidolin D, Guescini M, Battistin L, Stocchi V, De Caro R, Genedani S, Fuxe K. Aspects on the integrative actions of the brain from neural networks to "brain-body medicine". Journal of Receptor and Signal Transduction Research. 32: 163-80. PMID 22620712 DOI: 10.3109/10799893.2012.687748  0.372
2012 Ciruela F, Fernández-Dueñas V, Llorente J, Borroto-Escuela D, Cuffí ML, Carbonell L, Sánchez S, Agnati LF, Fuxe K, Tasca CI. G protein-coupled receptor oligomerization and brain integration: focus on adenosinergic transmission. Brain Research. 1476: 86-95. PMID 22575562 DOI: 10.1016/J.Brainres.2012.04.056  0.668
2012 Tarakanov AO, Fuxe KG, Borroto-Escuela DO. Integrin triplets of marine sponges in human brain receptor heteromers. Journal of Molecular Neuroscience : Mn. 48: 154-60. PMID 22573093 DOI: 10.1007/S12031-012-9793-6  0.585
2012 Borroto-Escuela DO, Romero-Fernandez W, Pérez-Alea M, Narvaez M, Tarakanov AO, Mudó G, Agnati LF, Ciruela F, Belluardo N, Fuxe K. The existence of FGFR1-5-HT1A receptor heterocomplexes in midbrain 5-HT neurons of the rat: relevance for neuroplasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6295-303. PMID 22553035 DOI: 10.1523/Jneurosci.4203-11.2012  0.638
2012 Palomares-Castillo E, Hernández-Pérez OR, Pérez-Carrera D, Crespo-Ramírez M, Fuxe K, Pérez de la Mora M. The intercalated paracapsular islands as a module for integration of signals regulating anxiety in the amygdala. Brain Research. 1476: 211-34. PMID 22516107 DOI: 10.1016/j.brainres.2012.03.047  0.369
2012 Agnati LF, Barlow P, Ghidoni R, Borroto-Escuela DO, Guidolin D, Fuxe K. Possible genetic and epigenetic links between human inner speech, schizophrenia and altruism. Brain Research. 1476: 38-57. PMID 22483963 DOI: 10.1016/J.Brainres.2012.02.074  0.514
2012 Ferraro L, Frankowska M, Marcellino D, Zaniewska M, Beggiato S, Filip M, Tomasini MC, Antonelli T, Tanganelli S, Fuxe K. A novel mechanism of cocaine to enhance dopamine d2-like receptor mediated neurochemical and behavioral effects. An in vivo and in vitro study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1856-66. PMID 22453136 DOI: 10.1038/npp.2012.33  0.703
2012 Fuxe K, Borroto-Escuela DO, Romero-Fernandez W, Ciruela F, Manger P, Leo G, Díaz-Cabiale Z, Agnati LF. On the role of volume transmission and receptor-receptor interactions in social behaviour: focus on central catecholamine and oxytocin neurons. Brain Research. 1476: 119-31. PMID 22373652 DOI: 10.1016/J.Brainres.2012.01.062  0.609
2012 Ferraro L, Beggiato S, Tomasini MC, Fuxe K, Antonelli T, Tanganelli S. A(2A)/D(2) receptor heteromerization in a model of Parkinson's disease. Focus on striatal aminoacidergic signaling. Brain Research. 1476: 96-107. PMID 22370145 DOI: 10.1016/j.brainres.2012.01.032  0.452
2012 De-Miguel FF, Fuxe K. Extrasynaptic neurotransmission as a way of modulating neuronal functions. Frontiers in Physiology. 3: 16. PMID 22363292 DOI: 10.3389/fphys.2012.00016  0.339
2012 Fuxe K, Borroto-Escuela DO, Marcellino D, Romero-Fernandez W, Frankowska M, Guidolin D, Filip M, Ferraro L, Woods AS, Tarakanov A, Ciruela F, Agnati LF, Tanganelli S. GPCR heteromers and their allosteric receptor-receptor interactions. Current Medicinal Chemistry. 19: 356-63. PMID 22335512 DOI: 10.2174/092986712803414259  0.64
2012 Filip M, Zaniewska M, Frankowska M, Wydra K, Fuxe K. The importance of the adenosine A(2A) receptor-dopamine D(2) receptor interaction in drug addiction. Current Medicinal Chemistry. 19: 317-55. PMID 22335511 DOI: 10.2174/092986712803414231  0.398
2012 Tanganelli S, Antonelli T, Tomasini MC, Beggiato S, Fuxe K, Ferraro L. Relevance of dopamine D(2)/neurotensin NTS1 and NMDA/neurotensin NTS1 receptor interaction in psychiatric and neurodegenerative disorders. Current Medicinal Chemistry. 19: 304-16. PMID 22335510 DOI: 10.2174/092986712803414268  0.458
2012 Guescini M, Leo G, Genedani S, Carone C, Pederzoli F, Ciruela F, Guidolin D, Stocchi V, Mantuano M, Borroto-Escuela DO, Fuxe K, Agnati LF. Microvesicle and tunneling nanotube mediated intercellular transfer of g-protein coupled receptors in cell cultures. Experimental Cell Research. 318: 603-13. PMID 22266577 DOI: 10.1016/J.Yexcr.2012.01.005  0.579
2012 Ferraro L, O'Connor WT, Beggiato S, Tomasini MC, Fuxe K, Tanganelli S, Antonelli T. Striatal NTS1 , dopamine D2 and NMDA receptor regulation of pallidal GABA and glutamate release--a dual-probe microdialysis study in the intranigral 6-hydroxydopamine unilaterally lesioned rat. The European Journal of Neuroscience. 35: 207-20. PMID 22211865 DOI: 10.1111/j.1460-9568.2011.07949.x  0.41
2012 Perez de la Mora M, Gallegos-Cari A, Crespo-Ramirez M, Marcellino D, Hansson AC, Fuxe K. Distribution of dopamine D(2)-like receptors in the rat amygdala and their role in the modulation of unconditioned fear and anxiety. Neuroscience. 201: 252-66. PMID 22100273 DOI: 10.1016/j.neuroscience.2011.10.045  0.782
2012 Tarakanov AO, Fuxe KG, Borroto-Escuela DO. On the origin of the triplet puzzle of homologies in receptor heteromers: Toll-like receptor triplets in different types of receptors. Journal of Neural Transmission (Vienna, Austria : 1996). 119: 517-23. PMID 22068823 DOI: 10.1007/S00702-011-0734-2  0.593
2012 Borroto-Escuela DO, Romero-Fernandez W, Mudó G, Pérez-Alea M, Ciruela F, Tarakanov AO, Narvaez M, Di Liberto V, Agnati LF, Belluardo N, Fuxe K. Fibroblast growth factor receptor 1- 5-hydroxytryptamine 1A heteroreceptor complexes and their enhancement of hippocampal plasticity. Biological Psychiatry. 71: 84-91. PMID 22035699 DOI: 10.1016/J.Biopsych.2011.09.012  0.639
2012 Marcellino D, Kehr J, Agnati LF, Fuxe K. Increased affinity of dopamine for D(2) -like versus D(1) -like receptors. Relevance for volume transmission in interpreting PET findings. Synapse (New York, N.Y.). 66: 196-203. PMID 22034017 DOI: 10.1002/syn.21501  0.739
2012 Borroto-Escuela DO, Agnati LF, Fuxe K, Ciruela F. Muscarinic acetylcholine receptor-interacting proteins (mAChRIPs): targeting the receptorsome. Current Drug Targets. 13: 53-71. PMID 22023407 DOI: 10.2174/138945012798868506  0.634
2012 Tarakanov AO, Fuxe KG, Borroto-Escuela DO. On the origin of the triplet puzzle of homologies in receptor heteromers: immunoglobulin triplets in different types of receptors. Journal of Molecular Neuroscience : Mn. 46: 616-21. PMID 21932037 DOI: 10.1007/S12031-011-9649-5  0.59
2012 Andersson K, Fuxe K, Eneroth P, Gustafsson JA, Skett P. On the catecholamine control of growth hormone regulation. Evidence for discrete changes in dopamine and noradrenaline turnover following growth hormone administration. Neuroscience Letters. 5: 83-9. PMID 19604975 DOI: 10.1016/0304-3940(77)90169-0  0.519
2012 Hökfelt T, Ljungdahl A, De La Mora MP, Fuxe K. Further evidence that apomorphine increases GABA turnover in the DA cell body rich and DA nerve terminal rich areas of the brain. Neuroscience Letters. 2: 239-42. PMID 19604848 DOI: 10.1016/0304-3940(76)90022-7  0.328
2012 Sahlholm K, Frisk S, Marcellino D, Nilsson J, Fuxe K, Århem P. P.1.030 Antagonist dissociation from dopamine D2 receptors: studies using a time-resolved ion channel activation assay European Neuropsychopharmacology. 22: S29. DOI: 10.1016/S0924-977X(12)70031-7  0.434
2011 Borroto-Escuela DO, Romero-Fernandez W, García-Negredo G, Correia PA, Garriga P, Fuxe K, Ciruela F. Dissecting the conserved NPxxY motif of the M3 muscarinic acetylcholine receptor: critical role of Asp-7.49 for receptor signaling and multiprotein complex formation. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 28: 1009-22. PMID 22178951 DOI: 10.1159/000335788  0.63
2011 Agnati LF, Guidolin D, Leo G, Guescini M, Pizzi M, Stocchi V, Spano PF, Ghidoni R, Ciruela F, Genedani S, Fuxe K. Possible new targets for GPCR modulation: allosteric interactions, plasma membrane domains, intercellular transfer and epigenetic mechanisms. Journal of Receptor and Signal Transduction Research. 31: 315-31. PMID 21929287 DOI: 10.3109/10799893.2011.599393  0.353
2011 Gago B, Suárez-Boomgaard D, Fuxe K, Brené S, Reina-Sánchez MD, Rodríguez-Pérez LM, Agnati LF, de la Calle A, Rivera A. Effect of acute and continuous morphine treatment on transcription factor expression in subregions of the rat caudate putamen. Marked modulation by D4 receptor activation. Brain Research. 1407: 47-61. PMID 21782156 DOI: 10.1016/j.brainres.2011.06.046  0.393
2011 Sahlholm K, Barchad-Avitzur O, Marcellino D, Gómez-Soler M, Fuxe K, Ciruela F, Arhem P. Agonist-specific voltage sensitivity at the dopamine D2S receptor--molecular determinants and relevance to therapeutic ligands. Neuropharmacology. 61: 937-49. PMID 21752340 DOI: 10.1016/J.Neuropharm.2011.06.022  0.75
2011 Alea MP, Borroto-Escuela DO, Romero-Fernandez W, Fuxe K, Garriga P. Differential expression of muscarinic acetylcholine receptor subtypes in Jurkat cells and their signaling. Journal of Neuroimmunology. 237: 13-22. PMID 21742386 DOI: 10.1016/J.Jneuroim.2011.05.010  0.571
2011 Borroto-Escuela DO, Tarakanov AO, Guidolin D, Ciruela F, Agnati LF, Fuxe K. Moonlighting characteristics of G protein-coupled receptors: focus on receptor heteromers and relevance for neurodegeneration. Iubmb Life. 63: 463-72. PMID 21698749 DOI: 10.1002/Iub.473  0.626
2011 Ferraro L, Beggiato S, Tomasini MC, Fuxe K, Tanganelli S, Antonelli T. Neurotensin regulates cortical glutamate transmission by modulating N-methyl-D-aspartate receptor functional activity: an in vivo microdialysis study. Journal of Neuroscience Research. 89: 1618-26. PMID 21656844 DOI: 10.1002/jnr.22686  0.31
2011 Romero-Fernandez W, Borroto-Escuela DO, Tarakanov AO, Mudó G, Narvaez M, Pérez-Alea M, Agnati LF, Ciruela F, Belluardo N, Fuxe K. Agonist-induced formation of FGFR1 homodimers and signaling differ among members of the FGF family. Biochemical and Biophysical Research Communications. 409: 764-8. PMID 21621521 DOI: 10.1016/J.Bbrc.2011.05.085  0.572
2011 Díaz-Cabiale Z, Parrado C, Narváez M, Puigcerver A, Millón C, Santín L, Fuxe K, Narváez JA. Galanin receptor/Neuropeptide Y receptor interactions in the dorsal raphe nucleus of the rat. Neuropharmacology. 61: 80-6. PMID 21396946 DOI: 10.1016/j.neuropharm.2011.03.002  0.44
2011 Van Craenenbroeck K, Borroto-Escuela DO, Romero-Fernandez W, Skieterska K, Rondou P, Lintermans B, Vanhoenacker P, Fuxe K, Ciruela F, Haegeman G. Dopamine D4 receptor oligomerization--contribution to receptor biogenesis. The Febs Journal. 278: 1333-44. PMID 21320289 DOI: 10.1111/J.1742-4658.2011.08052.X  0.617
2011 Ciruela F, Gómez-Soler M, Guidolin D, Borroto-Escuela DO, Agnati LF, Fuxe K, Fernández-Dueñas V. Adenosine receptor containing oligomers: their role in the control of dopamine and glutamate neurotransmission in the brain. Biochimica Et Biophysica Acta. 1808: 1245-55. PMID 21316336 DOI: 10.1016/J.Bbamem.2011.02.007  0.655
2011 Borroto-Escuela DO, Romero-Fernandez W, Tarakanov AO, Ciruela F, Agnati LF, Fuxe K. On the existence of a possible A2A-D2-β-Arrestin2 complex: A2A agonist modulation of D2 agonist-induced β-arrestin2 recruitment. Journal of Molecular Biology. 406: 687-99. PMID 21256133 DOI: 10.1016/J.Jmb.2011.01.022  0.571
2011 Borroto-Escuela DO, Van Craenenbroeck K, Romero-Fernandez W, Guidolin D, Woods AS, Rivera A, Haegeman G, Agnati LF, Tarakanov AO, Fuxe K. Dopamine D2 and D4 receptor heteromerization and its allosteric receptor-receptor interactions. Biochemical and Biophysical Research Communications. 404: 928-34. PMID 21184734 DOI: 10.1016/J.Bbrc.2010.12.083  0.618
2011 Borroto-Escuela DO, Correia PA, Romero-Fernandez W, Narvaez M, Fuxe K, Ciruela F, Garriga P. Muscarinic receptor family interacting proteins: role in receptor function. Journal of Neuroscience Methods. 195: 161-9. PMID 21134400 DOI: 10.1016/J.Jneumeth.2010.11.025  0.639
2011 Gravett N, Bhagwandin A, Fuxe K, Manger PR. Distribution of orexin-A immunoreactive neurons and their terminal networks in the brain of the rock hyrax, Procavia capensis. Journal of Chemical Neuroanatomy. 41: 86-96. PMID 21126575 DOI: 10.1016/J.Jchemneu.2010.11.005  0.3
2011 Guidolin D, Ciruela F, Genedani S, Guescini M, Tortorella C, Albertin G, Fuxe K, Agnati LF. Bioinformatics and mathematical modelling in the study of receptor-receptor interactions and receptor oligomerization: focus on adenosine receptors. Biochimica Et Biophysica Acta. 1808: 1267-83. PMID 20888789 DOI: 10.1016/J.Bbamem.2010.09.022  0.444
2011 Wydra K, Suder A, Zaniewska M, Dziubina A, Kaminska K, Golembiowska K, Fuxe K, Filip M. P.6.d.014 Behavioural and neurochemical effects of dopamine D2 and adenosine A2A receptor agonists on cocaine self-administration and relapse in rats European Neuropsychopharmacology. 21. DOI: 10.1016/S0924-977X(11)70965-8  0.413
2011 Sahlholm K, Frisk S, Fuxe K, Århem P. P.3.d.010 Investigation of antagonist unbinding from dopamine D2 receptors using a real-time ion channel activation assay European Neuropsychopharmacology. 21: S511-S512. DOI: 10.1016/S0924-977X(11)70832-X  0.371
2011 Wydra K, Zaniewska M, Suder A, Dziubina A, Kowalska K, Golembiowska K, Fuxe K, Filip M. P.2.023 In vivo microdialysis studies of brain dopamine, glutamate and GABA overflow during cocaine self-administration and its extinction European Neuropsychopharmacology. 21. DOI: 10.1016/S0924-977X(11)70062-1  0.342
2010 Díaz-Cabiale Z, Parrado C, Narváez M, Millón C, Puigcerver A, Fuxe K, Narváez JA. Neurochemical modulation of central cardiovascular control: the integrative role of galanin. Exs. 102: 113-31. PMID 21299065 DOI: 10.1007/978-3-0346-0228-0_9  0.39
2010 Vilardaga JP, Agnati LF, Fuxe K, Ciruela F. G-protein-coupled receptor heteromer dynamics. Journal of Cell Science. 123: 4215-20. PMID 21123619 DOI: 10.1242/Jcs.063354  0.376
2010 Borroto-Escuela DO, Romero-Fernandez W, Tarakanov AO, Gómez-Soler M, Corrales F, Marcellino D, Narvaez M, Frankowska M, Flajolet M, Heintz N, Agnati LF, Ciruela F, Fuxe K. Characterization of the A2AR-D2R interface: focus on the role of the C-terminal tail and the transmembrane helices. Biochemical and Biophysical Research Communications. 402: 801-7. PMID 21040702 DOI: 10.1016/J.Bbrc.2010.10.122  0.73
2010 Navarro G, Moreno E, Aymerich M, Marcellino D, McCormick PJ, Mallol J, Cortés A, Casadó V, Canela EI, Ortiz J, Fuxe K, Lluís C, Ferré S, Franco R. Direct involvement of sigma-1 receptors in the dopamine D1 receptor-mediated effects of cocaine. Proceedings of the National Academy of Sciences of the United States of America. 107: 18676-81. PMID 20956312 DOI: 10.1073/Pnas.1008911107  0.712
2010 Borroto-Escuela DO, Romero-Fernandez W, Tarakanov AO, Marcellino D, Ciruela F, Agnati LF, Fuxe K. Dopamine D2 and 5-hydroxytryptamine 5-HT(â‚‚A) receptors assemble into functionally interacting heteromers. Biochemical and Biophysical Research Communications. 401: 605-10. PMID 20888323 DOI: 10.1016/J.Bbrc.2010.09.110  0.745
2010 Kenakin T, Agnati LF, Caron M, Fredholm B, Guidoli D, Kobilka B, Lefkowitz RW, Lohse M, Woods A, Fuxe K. International Workshop at the Nobel Forum, Karolinska Institutet on G protein-coupled receptors: finding the words to describe monomers, oligomers, and their molecular mechanisms and defining their meaning. Can a consensus be reached? Journal of Receptor and Signal Transduction Research. 30: 284-6. PMID 20858022 DOI: 10.3109/10799893.2010.512438  0.639
2010 Fuxe K, Kenakin T. The changing world of G protein-coupled receptors. Journal of Receptor and Signal Transduction Research. 30: 271. PMID 20858021 DOI: 10.3109/10799893.2010.507367  0.325
2010 Frinchi M, Di Liberto V, Olivieri M, Fuxe K, Belluardo N, Mudò G. FGF-2/FGFR1 neurotrophic system expression level and its basal activation do not account for the age-dependent decline of precursor cell proliferation in the subventricular zone of rat brain. Brain Research. 1358: 39-45. PMID 20816673 DOI: 10.1016/j.brainres.2010.08.083  0.322
2010 Ciruela F, Vallano A, Arnau JM, Sánchez S, Borroto-Escuela DO, Agnati LF, Fuxe K, Fernández-Dueñas V. G protein-coupled receptor oligomerization for what? Journal of Receptor and Signal Transduction Research. 30: 322-30. PMID 20718634 DOI: 10.3109/10799893.2010.508166  0.628
2010 Flores-Gracia C, Nuche-Bricaire A, Crespo-Ramírez M, Miledi R, Fuxe K, Pérez de la Mora M. GABA(A) ρ receptor mechanisms in the rat amygdala and its role in the modulation of fear and anxiety. Psychopharmacology. 212: 475-84. PMID 20689940 DOI: 10.1007/s00213-010-1973-x  0.348
2010 Fuxe K, Marcellino D, Borroto-Escuela DO, Frankowska M, Ferraro L, Guidolin D, Ciruela F, Agnati LF. The changing world of G protein-coupled receptors: from monomers to dimers and receptor mosaics with allosteric receptor-receptor interactions. Journal of Receptor and Signal Transduction Research. 30: 272-83. PMID 20684666 DOI: 10.3109/10799893.2010.506191  0.774
2010 Marcellino D, Lindqvist E, Schneider M, Müller CE, Fuxe K, Olson L, Galter D. Chronic A2A antagonist treatment alleviates parkinsonian locomotor deficiency in MitoPark mice. Neurobiology of Disease. 40: 460-6. PMID 20656029 DOI: 10.1016/J.Nbd.2010.07.008  0.724
2010 Agnati LF, Guidolin D, Albertin G, Trivello E, Ciruela F, Genedani S, Tarakanov A, Fuxe K. An integrated view on the role of receptor mosaics at perisynaptic level: focus on adenosine A(2A), dopamine D(2), cannabinoid CB(1), and metabotropic glutamate mGlu(5) receptors. Journal of Receptor and Signal Transduction Research. 30: 355-69. PMID 20524778 DOI: 10.3109/10799893.2010.487492  0.449
2010 Díaz-Cabiale Z, Parrado C, Narváez M, Millón C, Puigcerver A, Fuxe K, Narváez JA. The Galanin N-terminal fragment (1-15) interacts with neuropeptide Y in central cardiovascular control: Involvement of the NPY Y2 receptor subtype. Regulatory Peptides. 163: 130-6. PMID 20451563 DOI: 10.1016/j.regpep.2010.04.014  0.413
2010 Agnati LF, Guidolin D, Vilardaga JP, Ciruela F, Fuxe K. On the expanding terminology in the GPCR field: the meaning of receptor mosaics and receptor heteromers. Journal of Receptor and Signal Transduction Research. 30: 287-303. PMID 20429829 DOI: 10.3109/10799891003786226  0.391
2010 Borroto-Escuela DO, García-Negredo G, Garriga P, Fuxe K, Ciruela F. The M(5) muscarinic acetylcholine receptor third intracellular loop regulates receptor function and oligomerization. Biochimica Et Biophysica Acta. 1803: 813-25. PMID 20398705 DOI: 10.1016/J.Bbamcr.2010.04.002  0.625
2010 Marcellino D, Suárez-Boomgaard D, Sánchez-Reina MD, Aguirre JA, Yoshitake T, Yoshitake S, Hagman B, Kehr J, Agnati LF, Fuxe K, Rivera A. On the role of P2X(7) receptors in dopamine nerve cell degeneration in a rat model of Parkinson's disease: studies with the P2X(7) receptor antagonist A-438079. Journal of Neural Transmission (Vienna, Austria : 1996). 117: 681-7. PMID 20387084 DOI: 10.1007/s00702-010-0400-0  0.732
2010 Ferraro L, Beggiato S, Marcellino D, Frankowska M, Filip M, Agnati LF, Antonelli T, Tomasini MC, Tanganelli S, Fuxe K. Nanomolar concentrations of cocaine enhance D2-like agonist-induced inhibition of the K+-evoked [3H]-dopamine efflux from rat striatal synaptosomes: a novel action of cocaine. Journal of Neural Transmission (Vienna, Austria : 1996). 117: 593-7. PMID 20354886 DOI: 10.1007/s00702-010-0389-4  0.704
2010 Fuxe K, Marcellino D, Borroto-Escuela DO, Guescini M, Fernández-Dueñas V, Tanganelli S, Rivera A, Ciruela F, Agnati LF. Adenosine-dopamine interactions in the pathophysiology and treatment of CNS disorders. Cns Neuroscience & Therapeutics. 16: e18-42. PMID 20345970 DOI: 10.1111/J.1755-5949.2009.00126.X  0.55
2010 Borroto-Escuela DO, Correia PA, Perez Alea M, Narvaez M, Garriga P, Fuxe K, Ciruela F. Impaired M(3) muscarinic acetylcholine receptor signal transduction through blockade of binding of multiple proteins to its third intracellular loop. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 25: 397-408. PMID 20332620 DOI: 10.1159/000303044  0.603
2010 Marcellino D, Navarro G, Sahlholm K, Nilsson J, Agnati LF, Canela EI, Lluís C, Ã…rhem P, Franco R, Fuxe K. Cocaine produces D2R-mediated conformational changes in the adenosine A(2A)R-dopamine D2R heteromer. Biochemical and Biophysical Research Communications. 394: 988-92. PMID 20307491 DOI: 10.1016/J.Bbrc.2010.03.104  0.691
2010 Borroto-Escuela DO, Marcellino D, Narvaez M, Flajolet M, Heintz N, Agnati L, Ciruela F, Fuxe K. A serine point mutation in the adenosine A2AR C-terminal tail reduces receptor heteromerization and allosteric modulation of the dopamine D2R. Biochemical and Biophysical Research Communications. 394: 222-7. PMID 20197060 DOI: 10.1016/J.Bbrc.2010.02.168  0.746
2010 Borroto-Escuela DO, Narvaez M, Marcellino D, Parrado C, Narvaez JA, Tarakanov AO, Agnati LF, Díaz-Cabiale Z, Fuxe K. Galanin receptor-1 modulates 5-hydroxtryptamine-1A signaling via heterodimerization. Biochemical and Biophysical Research Communications. 393: 767-72. PMID 20171159 DOI: 10.1016/J.Bbrc.2010.02.078  0.783
2010 Genedani S, Carone C, Guidolin D, Filaferro M, Marcellino D, Fuxe K, Agnati LF. Differential sensitivity of A2A and especially D2 receptor trafficking to cocaine compared with lipid rafts in cotransfected CHO cell lines. Novel actions of cocaine independent of the DA transporter. Journal of Molecular Neuroscience : Mn. 41: 347-57. PMID 20143275 DOI: 10.1007/s12031-010-9328-y  0.695
2010 Pieters RP, Gravett N, Fuxe K, Manger PR. Nuclear organization of cholinergic, putative catecholaminergic and serotonergic nuclei in the brain of the eastern rock elephant shrew, Elephantulus myurus. Journal of Chemical Neuroanatomy. 39: 175-88. PMID 20067831 DOI: 10.1016/J.Jchemneu.2010.01.001  0.323
2010 Fuxe K, Marcellino D, Leo G, Agnati LF. Molecular integration via allosteric interactions in receptor heteromers. A working hypothesis. Current Opinion in Pharmacology. 10: 14-22. PMID 19942481 DOI: 10.1016/j.coph.2009.10.010  0.736
2010 Fuxe K, Dahlström AB, Jonsson G, Marcellino D, Guescini M, Dam M, Manger P, Agnati L. The discovery of central monoamine neurons gave volume transmission to the wired brain. Progress in Neurobiology. 90: 82-100. PMID 19853007 DOI: 10.1016/j.pneurobio.2009.10.012  0.761
2010 de la Mora MP, Gallegos-Cari A, Arizmendi-García Y, Marcellino D, Fuxe K. Role of dopamine receptor mechanisms in the amygdaloid modulation of fear and anxiety: Structural and functional analysis. Progress in Neurobiology. 90: 198-216. PMID 19853006 DOI: 10.1016/j.pneurobio.2009.10.010  0.739
2010 Agnati LF, Guidolin D, Leo G, Carone C, Genedani S, Fuxe K. Receptor-receptor interactions: A novel concept in brain integration. Progress in Neurobiology. 90: 157-75. PMID 19850102 DOI: 10.1016/j.pneurobio.2009.10.004  0.435
2010 Bux F, Bhagwandin A, Fuxe K, Manger PR. Organization of cholinergic, putative catecholaminergic and serotonergic nuclei in the diencephalon, midbrain and pons of sub-adult male giraffes. Journal of Chemical Neuroanatomy. 39: 189-203. PMID 19808092 DOI: 10.1016/J.Jchemneu.2009.09.006  0.318
2010 Sahlholm K, Marcellino D, Nilsson J, Fuxe K, Århem P. Agonist-Specific Effects of TM V Serine Mutations on Dopamine D2S Receptor Voltage-Sensitivity Biophysical Journal. 98: 290a. DOI: 10.1016/J.Bpj.2009.12.1581  0.417
2009 Fuxe K, Marcellino D, Guidolin D, Woods AS, Agnati L. Brain receptor mosaics and their intramembrane receptor-receptor interactions: molecular integration in transmission and novel targets for drug development. Journal of Acupuncture and Meridian Studies. 2: 1-25. PMID 20633470 DOI: 10.1016/S2005-2901(09)60011-X  0.721
2009 Silva C, Fuxe K, Chadi G. Involvement of astroglial fibroblast growth factor-2 and microglia in the nigral 6-OHDA parkinsonism and a possible role of glucocorticoid hormone on the glial mediated local trophism and wound repair. Journal of Neural Transmission. Supplementum. 185-202. PMID 20411778 DOI: 10.1007/978-3-211-92660-4-15  0.35
2009 Ferraro L, Tomasini MC, Beggiato S, Guerrini R, Salvadori S, Fuxe K, Calzà L, Tanganelli S, Antonelli T. Emerging evidence for neurotensin receptor 1 antagonists as novel pharmaceutics in neurodegenerative disorders. Mini Reviews in Medicinal Chemistry. 9: 1429-38. PMID 19929816 DOI: 10.2174/138955709789957495  0.308
2009 Agnati LF, Fuxe K, Woods AS, Genedani S, Guidolin D. Theoretical considerations on the topological organization of receptor mosaics Current Protein and Peptide Science. 10: 559-569. PMID 19751189 DOI: 10.2174/138920309789630606  0.42
2009 Navarro G, Aymerich MS, Marcellino D, Cortés A, Casadó V, Mallol J, Canela EI, Agnati L, Woods AS, Fuxe K, Lluís C, Lanciego JL, Ferré S, Franco R. Interactions between calmodulin, adenosine A2A, and dopamine D2 receptors. The Journal of Biological Chemistry. 284: 28058-68. PMID 19632986 DOI: 10.1074/Jbc.M109.034231  0.72
2009 Fuxe K, Ogren SO, Agnati LF, Jonsson G. Further evidence that methergoline is a central 5-hydroxytryptamine receptor blocking agent. Neuroscience Letters. 9: 195-200. PMID 19605217 DOI: 10.1016/0304-3940(78)90071-X  0.56
2009 Fuxe K, Ogren SO, Agnati L, Gustafsson JA, Jonsson G. On the mechanism of action of the antidepressant drugs amitriptyline and nortriptyline. Evidence for 5-hydroxytryptamine receptor blocking activity. Neuroscience Letters. 6: 339-43. PMID 19605076 DOI: 10.1016/0304-3940(77)90095-7  0.562
2009 Gravett N, Bhagwandin A, Fuxe K, Manger PR. Nuclear organization and morphology of cholinergic, putative catecholaminergic and serotonergic neurons in the brain of the rock hyrax, Procavia capensis. Journal of Chemical Neuroanatomy. 38: 57-74. PMID 19559986 DOI: 10.1016/J.Jchemneu.2009.02.005  0.319
2009 Ferré S, Baler R, Bouvier M, Caron MG, Devi LA, Durroux T, Fuxe K, George SR, Javitch JA, Lohse MJ, Mackie K, Milligan G, Pfleger KD, Pin JP, Volkow ND, et al. Building a new conceptual framework for receptor heteromers. Nature Chemical Biology. 5: 131-4. PMID 19219011 DOI: 10.1038/Nchembio0309-131  0.611
2009 Antonelli T, Tomasini MC, Mazza R, Fuxe K, Gaetani S, Cuomo V, Tanganelli S, Ferraro L. Cannabinoid CB1 and cholecystokinin CCK2 receptors modulate, in an opposing way, electrically evoked [3H]GABA efflux from rat cerebral cortex cell cultures: possible relevance for cortical GABA transmission and anxiety. The Journal of Pharmacology and Experimental Therapeutics. 329: 708-17. PMID 19197005 DOI: 10.1124/jpet.109.150649  0.368
2009 Fuxe K, Marcellino D, Woods AS, Giuseppina L, Antonelli T, Ferraro L, Tanganelli S, Agnati LF. Integrated signaling in heterodimers and receptor mosaics of different types of GPCRs of the forebrain: relevance for schizophrenia. Journal of Neural Transmission (Vienna, Austria : 1996). 116: 923-39. PMID 19156349 DOI: 10.1007/S00702-008-0174-9  0.74
2009 Andén N, Butcher SG, Fuxe K. Protection of the neostriatal dopamine stores against reserpine by local treatment with metatyramine. Pharmacology & Toxicology. 28: 39-48. PMID 5467753 DOI: 10.1111/J.1600-0773.1969.Tb00527.X  0.362
2009 Andén N, Dahlström A, Fuxe K, Larsson K. Functional Role of the Nigro‐Neostriatal Dopamine Neurons*) Pharmacology & Toxicology. 24: 263-274. PMID 5297995 DOI: 10.1111/J.1600-0773.1966.Tb00389.X  0.364
2009 Ögren SO, Fuxe K, Agnati LF, Celani MF. Effects of antidepressant drugs on cerebral serotonin receptor mechanisms. Pharmacology & Toxicology. 56: 105-127. PMID 3984752 DOI: 10.1111/J.1600-0773.1985.Tb02503.X  0.359
2009 Sahlholm K, Marcellino D, Nilsson J, Fuxe K, Århem P. Differential Voltage-sensitivities Of Agonists At The Dopamine D2S Receptor Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.1986  0.43
2008 Fuxe K, Marcellino D, Guidolin D, Woods AS, Agnati LF. Heterodimers and receptor mosaics of different types of G-protein-coupled receptors. Physiology (Bethesda, Md.). 23: 322-32. PMID 19074740 DOI: 10.1152/Physiol.00028.2008  0.714
2008 Sahlholm K, Marcellino D, Nilsson J, Fuxe K, Arhem P. Voltage-sensitivity at the human dopamine D2S receptor is agonist-specific. Biochemical and Biophysical Research Communications. 377: 1216-21. PMID 18983826 DOI: 10.1016/J.Bbrc.2008.10.117  0.718
2008 Sahlholm K, Marcellino D, Nilsson J, Fuxe K, Arhem P. Differential voltage-sensitivity of D2-like dopamine receptors. Biochemical and Biophysical Research Communications. 374: 496-501. PMID 18652803 DOI: 10.1016/J.Bbrc.2008.07.052  0.733
2008 Marcellino D, Ferré S, Casadó V, Cortés A, Le Foll B, Mazzola C, Drago F, Saur O, Stark H, Soriano A, Barnes C, Goldberg SR, Lluis C, Fuxe K, Franco R. Identification of dopamine D1-D3 receptor heteromers. Indications for a role of synergistic D1-D3 receptor interactions in the striatum. The Journal of Biological Chemistry. 283: 26016-25. PMID 18644790 DOI: 10.1074/jbc.M710349200  0.729
2008 Rivera A, Peñafiel A, Megías M, Agnati LF, López-Téllez JF, Gago B, Gutiérrez A, de la Calle A, Fuxe K. Cellular localization and distribution of dopamine D(4) receptors in the rat cerebral cortex and their relationship with the cortical dopaminergic and noradrenergic nerve terminal networks. Neuroscience. 155: 997-1010. PMID 18620029 DOI: 10.1016/j.neuroscience.2008.05.060  0.451
2008 Woods AS, Marcellino D, Jackson SN, Franco R, Ferré S, Agnati LF, Fuxe K. How calmodulin interacts with the adenosine A(2A) and the dopamine D(2) receptors. Journal of Proteome Research. 7: 3428-34. PMID 18590318 DOI: 10.1021/Pr8001782  0.729
2008 Carriba P, Navarro G, Ciruela F, Ferré S, Casadó V, Agnati L, Cortés A, Mallol J, Fuxe K, Canela EI, Lluís C, Franco R. Detection of heteromerization of more than two proteins by sequential BRET-FRET. Nature Methods. 5: 727-33. PMID 18587404 DOI: 10.1038/Nmeth.1229  0.325
2008 Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P. Electrophysiology-based analysis of human histamine H(4) receptor pharmacology using GIRK channel coupling in Xenopus oocytes. European Journal of Pharmacology. 591: 52-8. PMID 18582456 DOI: 10.1016/J.Ejphar.2008.06.029  0.7
2008 Pérez de la Mora M, Jacobsen KX, Crespo-Ramírez M, Flores-Gracia C, Fuxe K. Wiring and volume transmission in rat amygdala. Implications for fear and anxiety. Neurochemical Research. 33: 1618-33. PMID 18473172 DOI: 10.1007/s11064-008-9722-9  0.33
2008 Limacher A, Bhagwandin A, Fuxe K, Manger PR. Nuclear organization and morphology of cholinergic, putative catecholaminergic and serotonergic neurons in the brain of the Cape porcupine (Hystrix africaeaustralis): increased brain size does not lead to increased organizational complexity. Journal of Chemical Neuroanatomy. 36: 33-52. PMID 18472246 DOI: 10.1016/J.Jchemneu.2008.03.007  0.315
2008 Fuxe KG, Tarakanov AO, Goncharova LB, Agnati LF. A new road to neuroinflammation in Parkinson's disease? Brain Research Reviews. 58: 453-8. PMID 18457883 DOI: 10.1016/j.brainresrev.2008.04.003  0.317
2008 Aguirre JA, Leo G, Cueto R, Andbjer B, Naylor A, Medhurst AD, Agnati LF, Fuxe K. The novel cyclooxygenase-2 inhibitor GW637185X protects against l-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity. Neuroreport. 19: 657-60. PMID 18382281 DOI: 10.1097/WNR.0b013e3282fb7898  0.336
2008 Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P. Voltage-dependence of the human dopamine D2 receptor. Synapse (New York, N.Y.). 62: 476-80. PMID 18361445 DOI: 10.1002/Syn.20509  0.743
2008 Marcellino D, Carriba P, Filip M, Borgkvist A, Frankowska M, Bellido I, Tanganelli S, Müller CE, Fisone G, Lluis C, Agnati LF, Franco R, Fuxe K. Antagonistic cannabinoid CB1/dopamine D2 receptor interactions in striatal CB1/D2 heteromers. A combined neurochemical and behavioral analysis. Neuropharmacology. 54: 815-23. PMID 18262573 DOI: 10.1016/J.Neuropharm.2007.12.011  0.748
2008 Fuxe K, Marcellino D, Rivera A, Diaz-Cabiale Z, Filip M, Gago B, Roberts DC, Langel U, Genedani S, Ferraro L, de la Calle A, Narvaez J, Tanganelli S, Woods A, Agnati LF. Receptor-receptor interactions within receptor mosaics. Impact on neuropsychopharmacology. Brain Research Reviews. 58: 415-52. PMID 18222544 DOI: 10.1016/J.Brainresrev.2007.11.007  0.46
2008 Ferraro L, Tomasini MC, Mazza R, Fuxe K, Fournier J, Tanganelli S, Antonelli T. Neurotensin receptors as modulators of glutamatergic transmission. Brain Research Reviews. 58: 365-73. PMID 18096238 DOI: 10.1016/j.brainresrev.2007.11.001  0.45
2008 Chadi G, Silva C, Maximino JR, Fuxe K, da Silva GO. Adrenalectomy counteracts the local modulation of astroglial fibroblast growth factor system without interfering with the pattern of 6-OHDA-induced dopamine degeneration in regions of the ventral midbrain. Brain Research. 1190: 23-38. PMID 18086466 DOI: 10.1016/j.brainres.2007.11.024  0.388
2008 Antonelli T, Tomasini MC, Fournier J, Mazza R, Tanganelli S, Pirondi S, Fuxe K, Ferraro L, Luca F. Neurotensin receptor involvement in the rise of extracellular glutamate levels and apoptotic nerve cell death in primary cortical cultures after oxygen and glucose deprivation. Cerebral Cortex (New York, N.Y. : 1991). 18: 1748-57. PMID 18063561 DOI: 10.1093/cercor/bhm217  0.372
2008 Agnati LF, Leo G, Genedani S, Andreoli N, Marcellino D, Woods A, Piron L, Guidolin D, Fuxe K. Structural plasticity in G-protein coupled receptors as demonstrated by the allosteric actions of homocysteine and computer-assisted analysis of disordered domains. Brain Research Reviews. 58: 459-74. PMID 18022243 DOI: 10.1016/J.Brainresrev.2007.10.003  0.401
2008 Rodrigues SL, Maseko BC, Ihunwo AO, Fuxe K, Manger PR. Nuclear organization and morphology of serotonergic neurons in the brain of the Nile crocodile, Crocodylus niloticus. Journal of Chemical Neuroanatomy. 35: 133-45. PMID 17923387 DOI: 10.1016/j.jchemneu.2007.08.007  0.306
2008 Dwarika S, Maseko BC, Ihunwo AO, Fuxe K, Manger PR. Distribution and morphology of putative catecholaminergic and serotonergic neurons in the brain of the greater canerat, Thryonomys swinderianus. Journal of Chemical Neuroanatomy. 35: 108-22. PMID 17884333 DOI: 10.1016/j.jchemneu.2007.08.005  0.307
2008 Borgkvist A, Marcellino D, Fuxe K, Greengard P, Fisone G. Regulation of DARPP-32 phosphorylation by Delta9-tetrahydrocannabinol. Neuropharmacology. 54: 31-5. PMID 17686497 DOI: 10.1016/J.Neuropharm.2007.06.025  0.739
2007 Pérez de la Mora M, Hernández-Gómez AM, Arizmendi-García Y, Jacobsen KX, Lara-García D, Flores-Gracia C, Crespo-Ramírez M, Gallegos-Cari A, Nuche-Bricaire A, Fuxe K. Role of the amygdaloid cholecystokinin (CCK)/gastrin-2 receptors and terminal networks in the modulation of anxiety in the rat. Effects of CCK-4 and CCK-8S on anxiety-like behaviour and [3H]GABA release. The European Journal of Neuroscience. 26: 3614-30. PMID 18088282 DOI: 10.1111/j.1460-9568.2007.05963.x  0.403
2007 Ferré S, Ciruela F, Quiroz C, Luján R, Popoli P, Cunha RA, Agnati LF, Fuxe K, Woods AS, Lluis C, Franco R. Adenosine receptor heteromers and their integrative role in striatal function. Thescientificworldjournal. 7: 74-85. PMID 17982579 DOI: 10.1100/Tsw.2007.211  0.46
2007 Antonelli T, Fuxe K, Tomasini MC, Mazzoni E, Agnati LF, Tanganelli S, Ferraro L. Neurotensin receptor mechanisms and its modulation of glutamate transmission in the brain: relevance for neurodegenerative diseases and their treatment. Progress in Neurobiology. 83: 92-109. PMID 17673354 DOI: 10.1016/j.pneurobio.2007.06.006  0.43
2007 Agnati LF, Leo G, Genedani S, Guidolin D, Andreoli N, Fuxe K. Possible relevance of receptor-receptor interactions between viral- and host-coded receptors for viral-induced disease. Thescientificworldjournal. 7: 1073-81. PMID 17619790 DOI: 10.1100/tsw.2007.166  0.41
2007 Fuxe K, Marcellino D, Genedani S, Agnati L. Adenosine A(2A) receptors, dopamine D(2) receptors and their interactions in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 22: 1990-2017. PMID 17618524 DOI: 10.1002/mds.21440  0.729
2007 Moon DJ, Maseko BC, Ihunwo AO, Fuxe K, Manger PR. Distribution and morphology of catecholaminergic and serotonergic neurons in the brain of the highveld gerbil, Tatera brantsii. Journal of Chemical Neuroanatomy. 34: 134-44. PMID 17606363 DOI: 10.1016/j.jchemneu.2007.06.001  0.313
2007 Fuxe K, Ferré S, Genedani S, Franco R, Agnati LF. Adenosine receptor-dopamine receptor interactions in the basal ganglia and their relevance for brain function. Physiology & Behavior. 92: 210-7. PMID 17572452 DOI: 10.1016/j.physbeh.2007.05.034  0.475
2007 Badlangana NL, Bhagwandin A, Fuxe K, Manger PR. Distribution and morphology of putative catecholaminergic and serotonergic neurons in the medulla oblongata of a sub-adult giraffe, Giraffa camelopardalis. Journal of Chemical Neuroanatomy. 34: 69-79. PMID 17544256 DOI: 10.1016/J.Jchemneu.2007.05.003  0.301
2007 Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P. The human histamine H3 receptor couples to GIRK channels in Xenopus oocytes. European Journal of Pharmacology. 567: 206-10. PMID 17537431 DOI: 10.1016/J.Ejphar.2007.04.032  0.697
2007 Agnati LF, Genedani S, Leo G, Rivera A, Guidolin D, Fuxe K. One century of progress in neuroscience founded on Golgi and Cajal's outstanding experimental and theoretical contributions. Brain Research Reviews. 55: 167-89. PMID 17467058 DOI: 10.1016/j.brainresrev.2007.03.004  0.338
2007 Ferraro L, Tomasini MC, Fuxe K, Agnati LF, Mazza R, Tanganelli S, Antonelli T. Mesolimbic dopamine and cortico-accumbens glutamate afferents as major targets for the regulation of the ventral striato-pallidal GABA pathways by neurotensin peptides. Brain Research Reviews. 55: 144-54. PMID 17448541 DOI: 10.1016/j.brainresrev.2007.03.006  0.391
2007 Fuxe K, Dahlström A, Höistad M, Marcellino D, Jansson A, Rivera A, Diaz-Cabiale Z, Jacobsen K, Tinner-Staines B, Hagman B, Leo G, Staines W, Guidolin D, Kehr J, Genedani S, et al. From the Golgi-Cajal mapping to the transmitter-based characterization of the neuronal networks leading to two modes of brain communication: wiring and volume transmission. Brain Research Reviews. 55: 17-54. PMID 17433836 DOI: 10.1016/J.Brainresrev.2007.02.009  0.716
2007 Guidolin D, Fuxe K, Neri G, Nussdorfer GG, Agnati LF. On the role of receptor-receptor interactions and volume transmission in learning and memory. Brain Research Reviews. 55: 119-33. PMID 17408566 DOI: 10.1016/j.brainresrev.2007.02.004  0.346
2007 Ferré S, Agnati LF, Ciruela F, Lluis C, Woods AS, Fuxe K, Franco R. Neurotransmitter receptor heteromers and their integrative role in 'local modules': the striatal spine module. Brain Research Reviews. 55: 55-67. PMID 17408563 DOI: 10.1016/J.Brainresrev.2007.01.007  0.467
2007 Gago B, Fuxe K, Agnati L, Peñafiel A, De La Calle A, Rivera A. Dopamine D(4) receptor activation decreases the expression of mu-opioid receptors in the rat striatum. The Journal of Comparative Neurology. 502: 358-66. PMID 17366605 DOI: 10.1002/cne.21327  0.422
2007 Marcellino D, Roberts DC, Navarro G, Filip M, Agnati L, Lluís C, Franco R, Fuxe K. Increase in A2A receptors in the nucleus accumbens after extended cocaine self-administration and its disappearance after cocaine withdrawal. Brain Research. 1143: 208-20. PMID 17320828 DOI: 10.1016/j.brainres.2007.01.079  0.712
2007 Mudò G, Belluardo N, Mauro A, Fuxe K. Acute intermittent nicotine treatment induces fibroblast growth factor-2 in the subventricular zone of the adult rat brain and enhances neuronal precursor cell proliferation. Neuroscience. 145: 470-83. PMID 17241745 DOI: 10.1016/j.neuroscience.2006.12.012  0.345
2007 Parrado C, Díaz-Cabiale Z, García-Coronel M, Agnati LF, Coveñas R, Fuxe K, Narváez JA. Region specific galanin receptor/neuropeptide Y Y1 receptor interactions in the tel- and diencephalon of the rat. Relevance for food consumption. Neuropharmacology. 52: 684-92. PMID 17087983 DOI: 10.1016/j.neuropharm.2006.09.010  0.405
2007 Fuxe K, Canals M, Torvinen M, Marcellino D, Terasmaa A, Genedani S, Leo G, Guidolin D, Diaz-Cabiale Z, Rivera A, Lundstrom L, Langel U, Narvaez J, Tanganelli S, Lluis C, et al. Intramembrane receptor-receptor interactions: a novel principle in molecular medicine. Journal of Neural Transmission (Vienna, Austria : 1996). 114: 49-75. PMID 17066251 DOI: 10.1007/S00702-006-0589-0  0.441
2007 Franco R, Lluis C, Canela EI, Mallol J, Agnati L, Casadó V, Ciruela F, Ferré S, Fuxe K. Receptor-receptor interactions involving adenosine A1 or dopamine D1 receptors and accessory proteins. Journal of Neural Transmission (Vienna, Austria : 1996). 114: 93-104. PMID 17024327 DOI: 10.1007/S00702-006-0566-7  0.473
2007 Díaz-Cabiale Z, Parrado C, Fuxe K, Agnati L, Narváez JA. Receptor-receptor interactions in central cardiovascular regulation. Focus on neuropeptide/alpha(2)-adrenoreceptor interactions in the nucleus tractus solitarius. Journal of Neural Transmission (Vienna, Austria : 1996). 114: 115-25. PMID 16988794 DOI: 10.1007/s00702-006-0559-6  0.328
2007 Antonelli T, Tomasini MC, Fuxe K, Agnati LF, Tanganelli S, Ferraro L. Receptor-receptor interactions as studied with microdialysis. Focus on NTR/D2 interactions in the basal ganglia. Journal of Neural Transmission (Vienna, Austria : 1996). 114: 105-13. PMID 16983483 DOI: 10.1007/s00702-006-0558-7  0.459
2007 Agnati LF, Guidolin D, Leo G, Fuxe K. A boolean network modelling of receptor mosaics relevance of topology and cooperativity. Journal of Neural Transmission (Vienna, Austria : 1996). 114: 77-92. PMID 16955372 DOI: 10.1007/s00702-006-0567-6  0.41
2007 Mudo G, Belluardo N, Fuxe K. Nicotinic receptor agonists as neuroprotective/neurotrophic drugs. Progress in molecular mechanisms. Journal of Neural Transmission (Vienna, Austria : 1996). 114: 135-47. PMID 16906354 DOI: 10.1007/s00702-006-0561-z  0.346
2007 Jiménez-Vasquez PA, Diaz-Cabiale Z, Caberlotto L, Bellido I, Overstreet D, Fuxe K, Mathé AA. Electroconvulsive stimuli selectively affect behavior and neuropeptide Y (NPY) and NPY Y(1) receptor gene expressions in hippocampus and hypothalamus of Flinders Sensitive Line rat model of depression. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 17: 298-308. PMID 16904299 DOI: 10.1016/j.euroneuro.2006.06.011  0.316
2007 Del Arco A, Mora F, Mohammed AH, Fuxe K. Stimulation of D2 receptors in the prefrontal cortex reduces PCP-induced hyperactivity, acetylcholine release and dopamine metabolism in the nucleus accumbens. Journal of Neural Transmission (Vienna, Austria : 1996). 114: 185-93. PMID 16897609 DOI: 10.1007/s00702-006-0533-3  0.406
2006 Agnati LF, Ferré S, Genedani S, Leo G, Guidolin D, Filaferro M, Carriba P, Casadó V, Lluis C, Franco R, Woods AS, Fuxe K. Allosteric modulation of dopamine D2 receptors by homocysteine. Journal of Proteome Research. 5: 3077-83. PMID 17081059 DOI: 10.1021/pr0601382  0.445
2006 Schwarzschild MA, Agnati L, Fuxe K, Chen JF, Morelli M. Targeting adenosine A2A receptors in Parkinson's disease. Trends in Neurosciences. 29: 647-54. PMID 17030429 DOI: 10.1016/J.Tins.2006.09.004  0.415
2006 Fuxe K, Manger P, Genedani S, Agnati L. The nigrostriatal DA pathway and Parkinson's disease. Journal of Neural Transmission. Supplementum. 71-83. PMID 17017512 DOI: 10.1007/978-3-211-45295-0_13  0.488
2006 Díaz-Cabiale Z, Parrado C, Rivera A, de la Calle A, Agnati L, Fuxe K, Narváez JA. Galanin-neuropeptide Y (NPY) interactions in central cardiovascular control: involvement of the NPY Y receptor subtype. The European Journal of Neuroscience. 24: 499-508. PMID 16903855 DOI: 10.1111/j.1460-9568.2006.04937.x  0.408
2006 Andrews ZB, Rivera A, Elsworth JD, Roth RH, Agnati L, Gago B, Abizaid A, Schwartz M, Fuxe K, Horvath TL. Uncoupling protein-2 promotes nigrostriatal dopamine neuronal function. The European Journal of Neuroscience. 24: 32-6. PMID 16882005 DOI: 10.1111/J.1460-9568.2006.04906.X  0.369
2006 Jacobsen KX, Höistad M, Staines WA, Fuxe K. The distribution of dopamine D1 receptor and mu-opioid receptor 1 receptor immunoreactivities in the amygdala and interstitial nucleus of the posterior limb of the anterior commissure: relationships to tyrosine hydroxylase and opioid peptide terminal systems. Neuroscience. 141: 2007-18. PMID 16820264 DOI: 10.1016/j.neuroscience.2006.05.054  0.454
2006 Pérez de la Mora M, Lara-García D, Jacobsen KX, Vázquez-García M, Crespo-Ramírez M, Flores-Gracia C, Escamilla-Marvan E, Fuxe K. Anxiolytic-like effects of the selective metabotropic glutamate receptor 5 antagonist MPEP after its intra-amygdaloid microinjection in three different non-conditioned rat models of anxiety. The European Journal of Neuroscience. 23: 2749-59. PMID 16817878 DOI: 10.1111/j.1460-9568.2006.04798.x  0.396
2006 Antonelli T, Fuxe K, Agnati L, Mazzoni E, Tanganelli S, Tomasini MC, Ferraro L. Experimental studies and theoretical aspects on A2A/D2 receptor interactions in a model of Parkinson's disease. Relevance for L-dopa induced dyskinesias. Journal of the Neurological Sciences. 248: 16-22. PMID 16765381 DOI: 10.1016/j.jns.2006.05.019  0.401
2006 Filip M, Frankowska M, Zaniewska M, PrzegaliÅ„ski E, Muller CE, Agnati L, Franco R, Roberts DC, Fuxe K. Involvement of adenosine A2A and dopamine receptors in the locomotor and sensitizing effects of cocaine. Brain Research. 1077: 67-80. PMID 16516871 DOI: 10.1016/j.brainres.2006.01.038  0.338
2006 Franco R, Casadó V, Mallol J, Ferrada C, Ferré S, Fuxe K, Cortés A, Ciruela F, Lluis C, Canela EI. The two-state dimer receptor model: a general model for receptor dimers. Molecular Pharmacology. 69: 1905-12. PMID 16501032 DOI: 10.1124/Mol.105.020685  0.395
2006 Rivera A, Agnati LF, Horvath TL, Valderrama JJ, de La Calle A, Fuxe K. Uncoupling protein 2/3 immunoreactivity and the ascending dopaminergic and noradrenergic neuronal systems: relevance for volume transmission. Neuroscience. 137: 1447-61. PMID 16387447 DOI: 10.1016/j.neuroscience.2005.05.051  0.366
2006 Da Silva JN, Fuxe K, Manger PR. Nuclear parcellation of certain immunohistochemically identifiable neuronal systems in the midbrain and pons of the Highveld molerat (Cryptomys hottentotus). Journal of Chemical Neuroanatomy. 31: 37-50. PMID 16289497 DOI: 10.1016/j.jchemneu.2005.08.008  0.314
2005 Andersson M, Terasmaa A, Fuxe K, Strömberg I. Subchronic haloperidol increases CB(1) receptor binding and G protein coupling in discrete regions of the basal ganglia. Journal of Neuroscience Research. 82: 264-72. PMID 16175569 DOI: 10.1002/jnr.20630  0.43
2005 Antonelli T, Fuxe K, Tomasini MC, Bartoszyk GD, Seyfried CA, Tanganelli S, Ferraro L. Effects of sarizotan on the corticostriatal glutamate pathways. Synapse (New York, N.Y.). 58: 193-9. PMID 16138317 DOI: 10.1002/syn.20195  0.355
2005 Agnati LF, Fuxe K, Torvinen M, Genedani S, Franco R, Watson S, Nussdorfer GG, Leo G, Guidolin D. New methods to evaluate colocalization of fluorophores in immunocytochemical preparations as exemplified by a study on A2A and D2 receptors in Chinese hamster ovary cells. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 53: 941-53. PMID 16055748 DOI: 10.1369/jhc.4A6355.2005  0.351
2005 Agnati LF, Ferre S, Burioni R, Woods A, Genedani S, Franco R, Fuxe K. Existence and theoretical aspects of homomeric and heteromeric dopamine receptor complexes and their relevance for neurological diseases. Neuromolecular Medicine. 7: 61-78. PMID 16052039 DOI: 10.1385/Nmm:7:1-2:061  0.696
2005 Franco R, Ciruela F, Casadó V, Cortes A, Canela EI, Mallol J, Agnati LF, Ferré S, Fuxe K, Lluis C. Partners for adenosine A1 receptors. Journal of Molecular Neuroscience : Mn. 26: 221-32. PMID 16012195 DOI: 10.1385/Jmn:26:2-3:221  0.401
2005 Fuxe K, Ferré S, Canals M, Torvinen M, Terasmaa A, Marcellino D, Goldberg SR, Staines W, Jacobsen KX, Lluis C, Woods AS, Agnati LF, Franco R. Adenosine A2A and dopamine D2 heteromeric receptor complexes and their function. Journal of Molecular Neuroscience : Mn. 26: 209-20. PMID 16012194 DOI: 10.1385/Jmn:26:2-3:209  0.724
2005 Agnati LF, Tarakanov AO, Ferré S, Fuxe K, Guidolin D. Receptor-receptor interactions, receptor mosaics, and basic principles of molecular network organization: possible implications for drug development. Journal of Molecular Neuroscience : Mn. 26: 193-208. PMID 16012193 DOI: 10.1385/JMN:26:2-3:193  0.393
2005 Genedani S, Guidolin D, Leo G, Filaferro M, Torvinen M, Woods AS, Fuxe K, Ferré S, Agnati LF. Computer-assisted image analysis of caveolin-1 involvement in the internalization process of adenosine A2A-dopamine D2 receptor heterodimers. Journal of Molecular Neuroscience : Mn. 26: 177-84. PMID 16012191 DOI: 10.1385/Jmn:26:2-3:177  0.437
2005 Woods AS, Ciruela F, Fuxe K, Agnati LF, Lluis C, Franco R, Ferré S. Role of electrostatic interaction in receptor-receptor heteromerization. Journal of Molecular Neuroscience : Mn. 26: 125-32. PMID 16012186 DOI: 10.1385/Jmn:26:2-3:125  0.437
2005 Petersson M, Diaz-Cabiale Z, Angel Narváez J, Fuxe K, Uvnäs-Moberg K. Oxytocin increases the density of high affinity alpha(2)-adrenoceptors within the hypothalamus, the amygdala and the nucleus of the solitary tract in ovariectomized rats. Brain Research. 1049: 234-9. PMID 15967417 DOI: 10.1016/J.Brainres.2005.05.034  0.335
2005 Franco R, Casadó V, Mallol J, Ferré S, Fuxe K, Cortés A, Ciruela F, Lluis C, Canela EI. Dimer-based model for heptaspanning membrane receptors. Trends in Biochemical Sciences. 30: 360-6. PMID 15951182 DOI: 10.1016/J.Tibs.2005.05.010  0.375
2005 Díaz-Cabiale Z, Parrado C, Vela C, Razani H, Coveñas R, Fuxe K, Narváez JA. Role of galanin and galanin(1-15) on central cardiovascular control. Neuropeptides. 39: 185-90. PMID 15944010 DOI: 10.1016/j.npep.2004.12.009  0.323
2005 Agnati LF, Fuxe K, Ferré S. How receptor mosaics decode transmitter signals. Possible relevance of cooperativity. Trends in Biochemical Sciences. 30: 188-93. PMID 15817395 DOI: 10.1016/j.tibs.2005.02.010  0.404
2005 Torvinen M, Torri C, Tombesi A, Marcellino D, Watson S, Lluis C, Franco R, Fuxe K, Agnati LF. Trafficking of adenosine A2A and dopamine D2 receptors. Journal of Molecular Neuroscience : Mn. 25: 191-200. PMID 15784967 DOI: 10.1385/JMN:25:2:191  0.729
2005 de la Mora MP, Cárdenas-Cachón L, Vázquez-García M, Crespo-Ramírez M, Jacobsen K, Höistad M, Agnati L, Fuxe K. Anxiolytic effects of intra-amygdaloid injection of the D1 antagonist SCH23390 in the rat. Neuroscience Letters. 377: 101-5. PMID 15740845 DOI: 10.1016/j.neulet.2004.11.079  0.403
2005 Aguirre JA, Kehr J, Yoshitake T, Liu FL, Rivera A, Fernandez-Espinola S, Andbjer B, Leo G, Medhurst AD, Agnati LF, Fuxe K. Protection but maintained dysfunction of nigral dopaminergic nerve cell bodies and striatal dopaminergic terminals in MPTP-lesioned mice after acute treatment with the mGluR5 antagonist MPEP. Brain Research. 1033: 216-20. PMID 15694927 DOI: 10.1016/j.brainres.2004.11.040  0.375
2005 Uustare A, Vonk A, Terasmaa A, Fuxe K, Rinken A. Kinetic and functional properties of [3H]ZM241385, a high affinity antagonist for adenosine A2A receptors. Life Sciences. 76: 1513-26. PMID 15680315 DOI: 10.1016/j.lfs.2004.10.027  0.343
2005 Fuxe K, Rivera A, Jacobsen KX, Höistad M, Leo G, Horvath TL, Staines W, De la Calle A, Agnati LF. Dynamics of volume transmission in the brain. Focus on catecholamine and opioid peptide communication and the role of uncoupling protein 2. Journal of Neural Transmission (Vienna, Austria : 1996). 112: 65-76. PMID 15599605 DOI: 10.1007/S00702-004-0158-3  0.381
2005 Torvinen M, Marcellino D, Canals M, Agnati LF, Lluis C, Franco R, Fuxe K. Adenosine A2A receptor and dopamine D3 receptor interactions: evidence of functional A2A/D3 heteromeric complexes. Molecular Pharmacology. 67: 400-7. PMID 15539641 DOI: 10.1124/mol.104.003376  0.734
2004 Belluardo N, Mudò G, Blum M, Itoh N, Agnati L, Fuxe K. Nicotine-induced FGF-2 mRNA in rat brain is preserved during aging. Neurobiology of Aging. 25: 1333-42. PMID 15465631 DOI: 10.1016/J.Neurobiolaging.2004.01.002  0.315
2004 Torvinen M, Kozell LB, Neve KA, Agnati LF, Fuxe K. Biochemical identification of the dopamine D2 receptor domains interacting with the adenosine A2A receptor. Journal of Molecular Neuroscience : Mn. 24: 173-80. PMID 15456930 DOI: 10.1385/Jmn:24:2:173  0.452
2004 Ciruela F, Burgueño J, Casadó V, Canals M, Marcellino D, Goldberg SR, Bader M, Fuxe K, Agnati LF, Lluis C, Franco R, Ferré S, Woods AS. Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2A and dopamine D2 receptors. Analytical Chemistry. 76: 5354-63. PMID 15362892 DOI: 10.1021/Ac049295F  0.712
2004 Agnati LF, Leo G, Vergoni AV, Martínez E, Hockemeyer J, Lluis C, Franco R, Fuxe K, Ferré S. Neuroprotective effect of L-DOPA co-administered with the adenosine A2A receptor agonist CGS 21680 in an animal model of Parkinson's disease. Brain Research Bulletin. 64: 155-64. PMID 15342103 DOI: 10.1016/j.brainresbull.2004.06.003  0.393
2004 Wu HQ, Fuxe K, Schwarcz R. Neuronal A1 receptors mediate increase in extracellular kynurenic acid after local intrastriatal adenosine infusion. Journal of Neurochemistry. 90: 621-8. PMID 15255939 DOI: 10.1111/j.1471-4159.2004.02531.x  0.438
2004 Tanganelli S, Sandager Nielsen K, Ferraro L, Antonelli T, Kehr J, Franco R, Ferré S, Agnati LF, Fuxe K, Scheel-Krüger J. Striatal plasticity at the network level. Focus on adenosine A2A and D2 interactions in models of Parkinson's Disease. Parkinsonism & Related Disorders. 10: 273-80. PMID 15196505 DOI: 10.1016/j.parkreldis.2004.02.015  0.351
2004 Ferré S, Ciruela F, Canals M, Marcellino D, Burgueno J, Casadó V, Hillion J, Torvinen M, Fanelli F, Benedetti Pd Pd, Goldberg SR, Bouvier M, Fuxe K, Agnati LF, Lluis C, et al. Adenosine A2A-dopamine D2 receptor-receptor heteromers. Targets for neuro-psychiatric disorders. Parkinsonism & Related Disorders. 10: 265-71. PMID 15196504 DOI: 10.1016/J.Parkreldis.2004.02.014  0.75
2004 Bellido I, Hansson AC, Gómez-Luque AJ, Andbjer B, Agnati LF, Fuxe K. Corticosterone strongly increases the affinity of dorsal raphe 5-HT1A receptors. Neuroreport. 15: 1457-9. PMID 15194873 DOI: 10.1097/01.Wnr.0000130542.06764.7F  0.434
2004 Díaz-Cabiale Z, Olausson H, Sohlström A, Agnati LF, Narváez JA, Uvnäs-Moberg K, Fuxe K. Long-term modulation by postnatal oxytocin of the alpha 2-adrenoceptor agonist binding sites in central autonomic regions and the role of prenatal stress. Journal of Neuroendocrinology. 16: 183-90. PMID 15049848 DOI: 10.1111/J.0953-8194.2004.01146.X  0.306
2004 Antonelli T, Ferraro L, Fuxe K, Finetti S, Fournier J, Tanganelli S, De Mattei M, Tomasini MC. Neurotensin enhances endogenous extracellular glutamate levels in primary cultures of rat cortical neurons: involvement of neurotensin receptor in NMDA induced excitotoxicity. Cerebral Cortex (New York, N.Y. : 1991). 14: 466-73. PMID 15028650 DOI: 10.1093/Cercor/Bhh008  0.31
2004 Liu FL, Fuxe K, Belluardo N, Leo G, Agnati LF, Aguirre JA. Acute intermittent nicotine treatment produces a reduction in the total number of FGF-2 immunoreactive astroglial cells in the substantia nigra of the rat: a stereological analysis. Neuroscience Letters. 355: 181-4. PMID 14732461 DOI: 10.1016/J.Neulet.2003.10.077  0.319
2004 Canals M, Burgueño J, Marcellino D, Cabello N, Canela EI, Mallol J, Agnati L, Ferré S, Bouvier M, Fuxe K, Ciruela F, Lluis C, Franco R. Homodimerization of adenosine A2A receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer. Journal of Neurochemistry. 88: 726-34. PMID 14720222 DOI: 10.1046/J.1471-4159.2003.02200.X  0.728
2004 Del Arco A, Zhu S, Terasmaa A, Mohammed AH, Fuxe K. Hyperactivity to novelty induced by social isolation is not correlated with changes in D2 receptor function and binding in striatum. Psychopharmacology. 171: 148-55. PMID 13680076 DOI: 10.1007/s00213-003-1578-8  0.419
2004 Filip M, Frankowska M, Przegaliński E, Müller CE, Fuxe K. P5.005 Influence of adenosine A2A receptor agonist (CGS 21680) and antagonist (MSX-3) on the locomotor and sensitizing effects of cocaine European Neuropsychopharmacology. 14. DOI: 10.1016/S0924-977X(04)80468-1  0.406
2003 Fuxe K, Agnati LF, Jacobsen K, Hillion J, Canals M, Torvinen M, Tinner-Staines B, Staines W, Rosin D, Terasmaa A, Popoli P, Leo G, Vergoni V, Lluis C, Ciruela F, et al. Receptor heteromerization in adenosine A2A receptor signaling: relevance for striatal function and Parkinson's disease. Neurology. 61: S19-23. PMID 14663004 DOI: 10.1212/01.Wnl.0000095206.44418.5C  0.48
2003 Agnati LF, Franzen O, Ferré S, Leo G, Franco R, Fuxe K. Possible role of intramembrane receptor-receptor interactions in memory and learning via formation of long-lived heteromeric complexes: focus on motor learning in the basal ganglia. Journal of Neural Transmission. Supplementum. 1-28. PMID 12946046 DOI: 10.1007/978-3-7091-0643-3_1  0.378
2003 Canals M, Marcellino D, Fanelli F, Ciruela F, de Benedetti P, Goldberg SR, Neve K, Fuxe K, Agnati LF, Woods AS, Ferré S, Lluis C, Bouvier M, Franco R. Adenosine A2A-dopamine D2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer. The Journal of Biological Chemistry. 278: 46741-9. PMID 12933819 DOI: 10.1074/Jbc.M306451200  0.737
2003 Díaz-Cabiale Z, Fuxe K, Coveñas R, González-Barón S, Narváez JA. Angiotensin II modulates the cardiovascular responses to microinjection of NPY Y1 and NPY Y2 receptor agonists into the nucleus tractus solitarii of the rat. Brain Research. 983: 193-200. PMID 12914980 DOI: 10.1016/S0006-8993(03)03086-5  0.313
2003 Agnati LF, Ferré S, Lluis C, Franco R, Fuxe K. Molecular mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the striatopallidal GABA neurons. Pharmacological Reviews. 55: 509-50. PMID 12869660 DOI: 10.1124/pr.55.3.2  0.459
2003 Yoshitake T, Yamaguchi M, Nohta H, Ichinose F, Yoshida H, Yoshitake S, Fuxe K, Kehr J. Determination of histamine in microdialysis samples from rat brain by microbore column liquid chromatography following intramolecular excimer-forming derivatization with pyrene-labeling reagent. Journal of Neuroscience Methods. 127: 11-7. PMID 12865144 DOI: 10.1016/S0165-0270(03)00097-9  0.308
2003 Hansson AC, Sommer W, Rimondini R, Andbjer B, Strömberg I, Fuxe K. c-fos reduces corticosterone-mediated effects on neurotrophic factor expression in the rat hippocampal CA1 region. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 6013-22. PMID 12853419 DOI: 10.1523/Jneurosci.23-14-06013.2003  0.311
2003 Fuxe K, Jacobsen KX, Höistad M, Tinner B, Jansson A, Staines WA, Agnati LF. The dopamine D1 receptor-rich main and paracapsular intercalated nerve cell groups of the rat amygdala: relationship to the dopamine innervation. Neuroscience. 119: 733-46. PMID 12809694 DOI: 10.1016/S0306-4522(03)00148-9  0.458
2003 Franco R, Canals M, Marcellino D, Ferré S, Agnati L, Mallol J, Casadó V, Ciruela F, Fuxe K, Lluis C, Canela EI. Regulation of heptaspanning-membrane-receptor function by dimerization and clustering. Trends in Biochemical Sciences. 28: 238-43. PMID 12765835 DOI: 10.1016/S0968-0004(03)00065-3  0.713
2003 Karcz-Kubicha M, Antoniou K, Terasmaa A, Quarta D, Solinas M, Justinova Z, Pezzola A, Reggio R, Müller CE, Fuxe K, Goldberg SR, Popoli P, Ferré S. Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1281-91. PMID 12700682 DOI: 10.1038/Sj.Npp.1300167  0.334
2003 Del Arco A, Segovia G, Fuxe K, Mora F. Changes in dialysate concentrations of glutamate and GABA in the brain: an index of volume transmission mediated actions? Journal of Neurochemistry. 85: 23-33. PMID 12641724 DOI: 10.1046/J.1471-4159.2003.01692.X  0.343
2003 Ferré S, Ciruela F, Woods AS, Canals M, Burgueno J, Marcellino D, Karcz-Kubicha M, Hope BT, Morales M, Popoli P, Goldberg SR, Fuxe K, Lluis C, Franco R, Agnati L. Glutamate mGlu5-adenosine A2A-dopamine D2 receptor interactions in the striatum. Implications for drug therapy in neuro-psychiatric disorders and drug abuse Current Medicinal Chemistry - Central Nervous System Agents. 3: 1-26. DOI: 10.2174/1568015033357779  0.393
2003 Terasmaa A, Eller M, Fuxe K, Harro J, Rinken A. Effect of loss of the locus coeruleus noradrenergic projections by DSP-4 treatment on striatal dopamine D2 receptors Journal of Neurochemistry. 85: 18-18. DOI: 10.1046/J.1471-4159.85.S2.15_9.X  0.41
2003 Fuxe K, Ferré S, Woods A, Lluis C, Franco R, Agnati L. L.01 Novel strategies for treatment of schizophrenia and Parkinson's disease. Focus on receptor-receptor interactions in the basal ganglia European Neuropsychopharmacology. 13. DOI: 10.1016/S0924-977X(03)91596-3  0.366
2002 Andersen MB, Fuxe K, Werge T, Gerlach J. The adenosine A2A receptor agonist CGS 21680 exhibits antipsychotic-like activity in Cebus apella monkeys. Behavioural Pharmacology. 13: 639-44. PMID 12478214 DOI: 10.1097/01.fbp.0000047148.28986.67  0.301
2002 Antonelli T, Tomasini MC, Finetti S, Giardino L, Calzà L, Fuxe K, Soubriè P, Tanganelli S, Ferraro L. Neurotensin enhances glutamate excitotoxicity in mesencephalic neurons in primary culture. Journal of Neuroscience Research. 70: 766-73. PMID 12444598 DOI: 10.1002/jnr.10415  0.41
2002 Ferré S, Karcz-Kubicha M, Hope BT, Popoli P, Burgueño J, Gutiérrez MA, Casadó V, Fuxe K, Goldberg SR, Lluis C, Franco R, Ciruela F. Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: implications for striatal neuronal function. Proceedings of the National Academy of Sciences of the United States of America. 99: 11940-5. PMID 12189203 DOI: 10.1073/Pnas.172393799  0.455
2002 Torvinen M, Ginés S, Hillion J, Latini S, Canals M, Ciruela F, Bordoni F, Staines W, Pedata F, Agnati LF, Lluis C, Franco R, Ferré S, Fuxe K. Interactions among adenosine deaminase, adenosine A(1) receptors and dopamine D(1) receptors in stably cotransfected fibroblast cells and neurons. Neuroscience. 113: 709-19. PMID 12150791 DOI: 10.1016/S0306-4522(02)00058-1  0.459
2002 Díaz-Cabiale Z, Cordón MP, Coveñas R, Rivera A, Yanaihara N, Fuxe K, González-Barón S, Narváez JA. Propranolol blocks the tachycardia induced by galanin (1-15) but not by galanin (1-29). Regulatory Peptides. 107: 29-36. PMID 12137963 DOI: 10.1016/S0167-0115(02)00060-5  0.332
2002 Hansson AC, Fuxe K. Biphasic autoregulation of mineralocorticoid receptor mRNA in the medial septal nucleus by aldosterone. Neuroendocrinology. 75: 358-366. PMID 12065888 DOI: 10.1159/000059432  0.412
2002 Lepiku M, Järv J, Fuxe K, Rinken A. Reversible and irreversible components of [3H]-N-propylnorapomorphine interaction with rat striatal membranes Neuroscience Letters. 325: 111-114. PMID 12044634 DOI: 10.1016/S0304-3940(02)00250-1  0.318
2002 Díaz-Cabiale Z, Fuxe K, Narváez JA, Finetti S, Antonelli T, Tanganelli S, Ferraro L. Neurotensin-induced modulation of dopamine D2 receptors and their function in rat striatum: counteraction by a NTR1-like receptor antagonist. Neuroreport. 13: 763-766. PMID 11997683 DOI: 10.1097/00001756-200205070-00006  0.501
2002 Díaz-Cabiale Z, Vivó M, Del Arco A, O'Connor WT, Harte MK, Müller CE, Martínez E, Popoli P, Fuxe K, Ferré S. Metabotropic glutamate mGlu5 receptor-mediated modulation of the ventral striopallidal GABA pathway in rats. Interactions with adenosine A(2A) and dopamine D(2) receptors. Neuroscience Letters. 324: 154-8. PMID 11988350 DOI: 10.1016/S0304-3940(02)00179-9  0.464
2002 Ferraro L, Fuxe K, Tanganelli S, Tomasini MC, Rambert FA, Antonelli T. Differential enhancement of dialysate serotonin levels in distinct brain regions of the awake rat by modafinil: possible relevance for wakefulness and depression. Journal of Neuroscience Research. 68: 107-12. PMID 11933055 DOI: 10.1002/jnr.10196  0.302
2002 Hillion J, Canals M, Torvinen M, Casado V, Scott R, Terasmaa A, Hansson A, Watson S, Olah ME, Mallol J, Canela EI, Zoli M, Agnati LF, Ibanez CF, Lluis C, ... ... Fuxe K, et al. Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2 receptors. The Journal of Biological Chemistry. 277: 18091-7. PMID 11872740 DOI: 10.1074/jbc.M107731200  0.663
2002 Bellido I, Dı́az-Cabiale Z, Jiménez-Vasquez PA, Andbjer B, Mathé AA, Fuxe K. Increased density of galanin binding sites in the dorsal raphe in a genetic rat model of depression. Neuroscience Letters. 317: 101-105. PMID 11755250 DOI: 10.1016/S0304-3940(01)02446-6  0.343
2002 Fuxe K, Belluardo N, Olsson P-, Mudo G, Liu F-, Changeux J-. Regulation of FGF-2 gene by nicotinic receptors and its intracellular signaling mechanism in the rat brain European Neuropsychopharmacology. 12: 144. DOI: 10.1016/S0924-977X(02)80090-6  0.35
2001 Popoli P, Pèzzola A, Torvinen M, Reggio R, Pintor A, Scarchilli L, Fuxe K, Ferrè S. The Selective mGlu5 Receptor Agonist CHPG Inhibits Quinpirole-Induced Turning in 6-Hydroxydopamine-Lesioned Rats and Modulates the Binding Characteristics of Dopamine D2 Receptors in the Rat Striatum: Interactions with Adenosine A2a Receptors Neuropsychopharmacology. 25: 505-513. PMID 11557164 DOI: 10.1016/S0893-133X(01)00256-1  0.493
2001 Aguirre JA, Andbjer B, González-Barón S, Hansson A, Strömberg I, Agnati LF, Fuxe K. Group I mGluR antagonist AIDA protects nigral DA cells from MPTP-induced injury. Neuroreport. 12: 2615-7. PMID 11522935 DOI: 10.1097/00001756-200108280-00006  0.338
2001 Jansson A, Tinner B, Bancila M, Vergé D, Steinbusch HWM, Agnati LF, Fuxe K. Relationships of 5-hydroxytryptamine immunoreactive terminal-like varicosities to 5-hydroxytryptamine-2A receptor-immunoreactive neuronal processes in the rat forebrain Journal of Chemical Neuroanatomy. 22: 185-203. PMID 11522440 DOI: 10.1016/S0891-0618(01)00133-8  0.35
2001 Tanganelli S, Fuxe K, Antonelli T, O'Connor WT, Ferraro L. Cholecystokinin/dopamine/GABA interactions in the nucleus accumbens: biochemical and functional correlates. Peptides. 22: 1229-34. PMID 11457515 DOI: 10.1016/S0196-9781(01)00446-6  0.437
2001 Díaz-Cabiale Z, Hurd Y, Guidolin D, Finnman UB, Zoli M, Agnati LF, Vanderhaeghen JJ, Fuxe K, Ferré S. Adenosine A2A agonist CGS 21680 decreases the affinity of dopamine D2 receptors for dopamine in human striatum. Neuroreport. 12: 1831-4. PMID 11435907 DOI: 10.1097/00001756-200107030-00014  0.473
2001 Ferré S, Popoli P, Giménez-Llort L, Rimondini R, Müller CE, Strömberg I, Ögren SO, Fuxe K. Adenosine/dopamine interaction: implications for the treatment of Parkinson's disease. Parkinsonism & Related Disorders. 7: 235-241. PMID 11331192 DOI: 10.1016/S1353-8020(00)00063-8  0.42
2001 Rinken A, Terasmaa A, Raidaru G, Fuxe K. D2 dopamine receptor-G protein coupling. Cross-regulation of agonist and guanosine nucleotide binding sites Neuroscience Letters. 302: 5-8. PMID 11278098 DOI: 10.1016/S0304-3940(01)01568-3  0.424
2001 Ferraro L, Tomasini MC, Fernandez M, Bebe BW, O'Connor WT, Fuxe K, Glennon JC, Tanganelli S, Antonelli T. Nigral neurotensin receptor regulation of nigral glutamate and nigroventral thalamic GABA transmission: a dual-probe microdialysis study in intact conscious rat brain. Neuroscience. 102: 113-20. PMID 11226674 DOI: 10.1016/S0306-4522(00)00448-6  0.381
2001 Diaz-Cabiale Z, Narvaez JA, Garcia-Coronel M, Fuxe K. Galanin/α2-adrenoceptor interactions in telencephalic and diencephalic regions of the rat Neuroreport. 12: 151-155. PMID 11201077 DOI: 10.1097/00001756-200101220-00038  0.313
2001 Razani H, Dı́az-Cabiale Z, Misane I, Wang F, Fuxe K, Ögren SO. Prolonged effects of intraventricular galanin on a 5-hydroxytryptamine1A receptor mediated function in the rat Neuroscience Letters. 299: 145-149. PMID 11166958 DOI: 10.1016/S0304-3940(00)01788-2  0.392
2001 Ögren S, Razani H, Kehr J, Fuxe K, Díaz-Cabiale Z, Misane I. The neuropeptide galanin: A modulator of 5-HT1A receptor mechanisms of relevance for affective disorders European Neuropsychopharmacology. 11: S168-S169. DOI: 10.1016/S0924-977X(01)80104-8  0.366
2001 Razani H, Dı́az-Cabiale Z, Misane I, Wang F, Fuxe K, Ögren SO. Erratum to “Prolonged effects of intraventricular galanin on a 5-hydroxytryptamine1A receptor mediated function in the rat” [Neurosci. Lett. 299 (2001) 145–149] Neuroscience Letters. 302: 160. DOI: 10.1016/S0304-3940(01)01645-7  0.4
2001 Franco R, Ferré S, Torvinen M, Ginés S, Hillion J, Ciruela F, Canela EI, Mallol J, Casadó V, Lluis C, Fuxe K. Adenosine/dopamine receptor-receptor interactions in the central nervous system Drug Development Research. 52: 296-302. DOI: 10.1002/Ddr.1127  0.506
2000 Caberlotto L, Fuxe K, Hurd YL. Characterization of NPY mRNA-expressing cells in the human brain: co-localization with Y2 but not Y1 mRNA in the cerebral cortex, hippocampus, amygdala, and striatum. Journal of Chemical Neuroanatomy. 20: 327-37. PMID 11207429 DOI: 10.1016/S0891-0618(00)00107-1  0.3
2000 Belluardo N, Mudo G, Blum M, Amato G, Fuxe K. Neurotrophic effects of central nicotinic receptor activation. Journal of Neural Transmission-Supplement. 227-245. PMID 11205143 DOI: 10.1007/978-3-7091-6301-6_15  0.362
2000 Razani H, Diaz-Cabiale Z, Fuxe K, Ögren SO. Intraventricular galanin produces a time-dependent modulation of 5-HT1A receptors in the dorsal raphe of the rat. Neuroreport. 11: 3943-3948. PMID 11192606 DOI: 10.1097/00001756-200012180-00008  0.361
2000 Díaz-Cabiale Z, Petersson M, Narváez JA, Uvnäs-Moberg K, Fuxe K. Systemic oxytocin treatment modulates alpha 2-adrenoceptors in telencephalic and diencephalic regions of the rat. Brain Research. 887: 421-5. PMID 11134634 DOI: 10.1016/S0006-8993(00)03017-1  0.336
2000 Díaz-Cabiale Z, Narváez JA, Garrido R, Petersson M, Uvnäs-Moberg K, Fuxe K. Antagonistic oxytocin/alpha2-adrenoreceptor interactions in the nucleus tractus solitarii: relevance for central cardiovascular control. Journal of Neuroendocrinology. 12: 1167-73. PMID 11106973 DOI: 10.1046/j.1365-2826.2000.00571.x  0.36
2000 Martire M, Altobelli D, Maurizi S, Preziosi P, Fuxe K. K+-evoked [3H]D-aspartate release in rat spinal cord synaptosomes: modulation by Neuropeptide Y and calcium channel antagonists. Journal of Neuroscience Research. 62: 722-729. PMID 11104511 DOI: 10.1002/1097-4547(20001201)62:5<722::Aid-Jnr12>3.0.Co;2-O  0.329
2000 Jansson A, Lippoldt A, Mazel T, Bartfai T, Ögren S, Syková E, Agnati LF, Fuxe K. Long distance signalling in volume transmission. Focus on clearance mechanisms Progress in Brain Research. 125: 399-413. PMID 11098675 DOI: 10.1016/S0079-6123(00)25028-0  0.326
2000 Ferré S, Fuxe K. Adenosine as a volume transmission signal. A feedback detector of neuronal activation. Progress in Brain Research. 125: 353-361. PMID 11098671 DOI: 10.1016/S0079-6123(00)25024-3  0.479
2000 Strömberg I, Kehr J, Fuxe K. Restoration of dopamine transmission in graft reinnervated striatum. Evidence for regulation of dopamine D2 receptor function in regions lacking dopamine. Progress in Brain Research. 125: 309-15. PMID 11098667 DOI: 10.1016/S0079-6123(00)25020-6  0.415
2000 Agnati LF, Zoli M, Ferrari R, Di Paola L, Torri C, Fuxe K, Zini I. Evidence for the existence of pulses of dopamine in the extracellular space of the rat striatum. Progress in Brain Research. 125: 303-8. PMID 11098666 DOI: 10.1016/S0079-6123(00)25019-X  0.373
2000 Kehr J, Höistad M, Fuxe K. Diffusion of radiolabeled dopamine, its metabolites and mannitol in the rat striatum studied by dual-probe microdialysis. Progress in Brain Research. 125: 179-90. PMID 11098656 DOI: 10.1016/S0079-6123(00)25009-7  0.356
2000 Strömberg I, Popoli P, Müller CE, Ferré S, Fuxe K. Electrophysiological and behavioural evidence for an antagonistic modulatory role of adenosine A2A receptors in dopamine D2 receptor regulation in the rat dopamine-denervated striatum. The European Journal of Neuroscience. 12: 4033-7. PMID 11069599 DOI: 10.1046/J.1460-9568.2000.00288.X  0.486
2000 Franco R, Ferré S, Agnati L, Torvinen M, Ginés S, Hillion J, Casadó V, Lledó P, Zoli M, Lluis C, Fuxe K. Evidence for adenosine/dopamine receptor interactions: indications for heteromerization. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: S50-9. PMID 11008067 DOI: 10.1016/S0893-133X(00)00144-5  0.498
2000 Terasmaa A, Andbjer B, Fuxe K, Rinken A. Striatal dopamine denervation decreases the GDP binding affinity in rat striatal membranes. Neuroreport. 11: 2691-2694. PMID 10976945 DOI: 10.1097/00001756-200008210-00017  0.408
2000 Hansson AC, Cintra A, Belluardo N, Sommer W, Bhatnagar M, Bader M, Ganten D, Fuxe K. Gluco- and mineralocorticoid receptor-mediated regulation of neurotrophic factor gene expression in the dorsal hippocampus and the neocortex of the rat. The European Journal of Neuroscience. 12: 2918-34. PMID 10971634 DOI: 10.1046/j.1460-9568.2000.00185.x  0.544
2000 Ferraro L, Fuxe K, Tanganelli S, Fernandez M, Rambert FA, Antonelli T. Amplification of cortical serotonin release: a further neurochemical action of the vigilance-promoting drug modafinil. Neuropharmacology. 39: 1974-83. PMID 10963741 DOI: 10.1016/S0028-3908(00)00019-8  0.3
2000 Höistad M, Kehr J, Andbjer B, Jansson A, Fuxe K. Intracerebral infusion of H-dopamine and H-mannitol in the striatum of halothane-anaesthetized male rats. A dual-probe microdialysis study of long-distance diffusion. The European Journal of Neuroscience. 12: 2505-14. PMID 10947826 DOI: 10.1046/j.1460-9568.2000.00141.x  0.325
2000 Belluardo N, Mudò G, Blum M, Fuxe K. Central nicotinic receptors, neurotrophic factors and neuroprotection. Behavioural Brain Research. 113: 21-34. PMID 10942029 DOI: 10.1016/S0166-4328(00)00197-2  0.347
2000 Ginés S, Hillion J, Torvinen M, Le Crom S, Casadó V, Canela EI, Rondin S, Lew JY, Watson S, Zoli M, Agnati LF, Verniera P, Lluis C, Ferré S, Fuxe K, et al. Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes. Proceedings of the National Academy of Sciences of the United States of America. 97: 8606-11. PMID 10890919 DOI: 10.1073/Pnas.150241097  0.317
2000 Narváez JA, Dı́az-Cabiale Z, Hedlund PB, Aguirre JA, Coveñas R, González-Barón S, Fuxe K. The galanin receptor antagonist M40 blocks the central cardiovascular actions of the galanin N-terminal fragment (1-15). European Journal of Pharmacology. 399: 197-203. PMID 10884520 DOI: 10.1016/S0014-2999(00)00383-6  0.377
2000 Strömberg I, Kehr J, Andbjer B, Fuxe K. Fetal ventral mesencephalic grafts functionally reduce the dopamine D2 receptor supersensitivity in partially dopamine reinnervated host striatum. Experimental Neurology. 164: 154-65. PMID 10877926 DOI: 10.1006/exnr.2000.7421  0.435
2000 Dı́az-Cabiale Z, Narváez JA, Yanaihara N, González-Barón S, Fuxe K. Galanin/alpha2-receptor interactions in central cardiovascular control. Neuropharmacology. 39: 1377-1385. PMID 10818254 DOI: 10.1016/S0028-3908(99)00225-7  0.404
2000 Marti M, Sbrenna S, Fuxe K, Bianchi C, Beani L, Morari M. Increased responsivity of glutamate release from the substantia nigra pars reticulata to striatal NMDA receptor blockade in a model of Parkinson's disease. A dual probe microdialysis study in hemiparkinsonian rats. The European Journal of Neuroscience. 12: 1848-50. PMID 10792462 DOI: 10.1046/J.1460-9568.2000.00081.X  0.395
2000 Heijtz RD, Ögren SO, Fuxe K. Ontogeny of the motor inhibitory role of dopamine D3 receptor subtype in rats European Journal of Pharmacology. 392: 35-39. PMID 10748270 DOI: 10.1016/S0014-2999(00)00112-6  0.388
2000 Díaz-cabiale Z, Narváez JA, Finnman U, Bellido I, Ögren SO, Fuxe K. Galanin-(1-16) modulates 5-HTIA receptors in the ventral limbic cortex of the rat Neuroreport. 11: 515-519. PMID 10718306 DOI: 10.1097/00001756-200002280-00018  0.43
2000 Terasmaa A, Finnman UB, Owman C, Ferré S, Fuxe K, Rinken A. Modulation of [(35)S]GTPgammaS binding to chinese hamster ovary cell membranes by D(2(short)) dopamine receptors. Neuroscience Letters. 280: 135-8. PMID 10686396 DOI: 10.1016/S0304-3940(00)00776-X  0.574
2000 Jansson A, Tinner B, Andbjer B, Razani H, Wang F-, Schött PA, Agnati LF, Ögren SO, Fuxe K. Internalization of Intracerebrally Administered Porcine Galanin (1–29) by a Discrete Nerve Cell Population in the Hippocampus of the Rat ☆ Experimental Neurology. 161: 153-166. PMID 10683281 DOI: 10.1006/Exnr.1999.7266  0.305
2000 Salim H, Ferré S, Dalal A, Peterfreund RA, Fuxe K, Vincent JD, Lledo PM. Activation of adenosine A1 and A2A receptors modulates dopamine D2 receptor-induced responses in stably transfected human neuroblastoma cells. Journal of Neurochemistry. 74: 432-9. PMID 10617149 DOI: 10.1046/j.1471-4159.2000.0740432.x  0.469
2000 Belluardo N, Mudo G, Blum M, Fuxe K. Nicotinic receptors and neurotrophic factors European Neuropsychopharmacology. 10: 176-177. DOI: 10.1016/S0924-977X(00)80083-8  0.335
1999 Belluardo N, Mudò G, Caniglia G, Cheng Q, Blum M, Fuxe K. The nicotinic acetylcholine receptor agonist ABT-594 increases FGF-2 expression in various rat brain regions. Neuroreport. 10: 3909-3913. PMID 10716232 DOI: 10.1097/00001756-199912160-00034  0.366
1999 Belluardo N, Mudò G, Blum M, Cheng Q, Caniglia G, Dell'Albani P, Fuxe K. The nicotinic acetylcholine receptor agonist (+/-)-epibatidine increases FGF-2 mRNA and protein levels in the rat brain. Molecular Brain Research. 74: 98-110. PMID 10640680 DOI: 10.1016/S0169-328X(99)00266-1  0.356
1999 Ferré S, Rimondini R, Popoli P, Reggio R, Pèzzola A, Hansson AC, Andersson A, Fuxe K. Stimulation of adenosine A1 receptors attenuates dopamine D1 receptor-mediated increase of NGFI-A, c-fos and jun-B mRNA levels in the dopamine-denervated striatum and dopamine D1 receptor-mediated turning behaviour. European Journal of Neuroscience. 11: 3884-3892. PMID 10583477 DOI: 10.1046/J.1460-9568.1999.00810.X  0.486
1999 Aguirre JA, Cintra A, Hillion J, Narváez JA, Jansson A, Antonelli T, Ferraro L, Rambert FA, Fuxe K. A stereological study on the neuroprotective actions of acute modafinil treatment on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced nigral lesions of the male black mouse. Neuroscience Letters. 275: 215-8. PMID 10580713 DOI: 10.1016/S0304-3940(99)00706-5  0.355
1999 Cintra A, Aguirre JA, Andbjer B, Finnman U-, Hagman M, Agnati LF, Höglund C, Möller A, Fuxe K. Subchronic toluene exposure in low concentrations produces signs of reduced dysfunction in the 6-hydroxydopamine lesioned nigrostriatal dopaminergic system of the rat. Neuroscience Letters. 274: 5-8. PMID 10530506 DOI: 10.1016/S0304-3940(99)00112-3  0.338
1999 Kull B, Ferré S, Arslan G, Svenningsson P, Fuxe K, Owman C, Fredholm BB. Reciprocal interactions between adenosine A2A and dopamine D2 receptors in Chinese hamster ovary cells co-transfected with the two receptors. Biochemical Pharmacology. 58: 1035-45. PMID 10509756 DOI: 10.1016/S0006-2952(99)00184-7  0.754
1999 Rimondini R, Fuxe K, Ferré S. Multiple intramembrane receptor-receptor interactions in the regulation of striatal dopamine D2 receptors. Neuroreport. 10: 2051-2054. PMID 10424673 DOI: 10.1097/00001756-199907130-00011  0.487
1999 Lillrank SM, Lipska BK, Weinberger DR, Fredholm BB, Fuxe K, Ferré S. Adenosine and dopamine receptor antagonist binding in the rat ventral and dorsal striatum: lack of changes after a neonatal bilateral lesion of the ventral hippocampus. Neurochemistry International. 34: 235-44. PMID 10355490 DOI: 10.1016/S0197-0186(99)00008-X  0.69
1999 Caberlotto L, Jimenez P, Overstreet DH, Hurd YL, Mathé AA, Fuxe K. Alterations in neuropeptide Y levels and Y1 binding sites in the Flinders Sensitive Line rats, a genetic animal model of depression. Neuroscience Letters. 265: 191-4. PMID 10327163 DOI: 10.1016/S0304-3940(99)00234-7  0.343
1999 Rinken A, Ferré S, Terasmaa A, Owman C, Fuxe K. Serotonergic agonists behave as partial agonists at the dopamine D2 receptor. Neuroreport. 10: 493-5. PMID 10208577 DOI: 10.1097/00001756-199902250-00009  0.628
1999 Ferré S, Popoli P, Rimondini R, Reggio R, Kehr J, Fuxe K. Adenosine A2A and group I metabotropic glutamate receptors synergistically modulate the binding characteristics of dopamine D2 receptors in the rat striatum. Neuropharmacology. 38: 129-40. PMID 10193904 DOI: 10.1016/S0028-3908(98)00154-3  0.462
1999 Ferraro L, Antonelli T, Tanganelli S, O'Connor WT, Perez de la Mora M, Mendez-Franco J, Rambert FA, Fuxe K. The vigilance promoting drug modafinil increases extracellular glutamate levels in the medial preoptic area and the posterior hypothalamus of the conscious rat: prevention by local GABAA receptor blockade. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 20: 346-56. PMID 10088135 DOI: 10.1016/S0893-133X(98)00085-2  0.713
1999 Jansson A, Goldstein M, Tinner B, Zoli M, Meador-Woodruff JH, Lew JY, Levey AI, Watson S, Agnati LF, Fuxe K. On the distribution patterns of D1, D2, tyrosine hydroxylase and dopamine transporter immunoreactivities in the ventral striatum of the rat. Neuroscience. 89: 473-89. PMID 10077329 DOI: 10.1016/S0306-4522(98)00317-0  0.472
1999 Marti M, Sbrenna S, Fuxe K, Bianchi C, Beani L, Morari M. In vitro evidence for increased facilitation of striatal acetylcholine release via pre- and postsynaptic NMDA receptors in hemiparkinsonian rats. Journal of Neurochemistry. 72: 875-8. PMID 9930765 DOI: 10.1046/J.1471-4159.1999.720875.X  0.355
1999 Misane I, Razani H, Wang FH, Jansson A, Fuxe K, Ogren SO. Modulation of a 5-HT1A receptor-mediated behavioral response by the neuropeptide galanin. Annals of the New York Academy of Sciences. 863: 442-4. PMID 9928195 DOI: 10.1111/j.1749-6632.1998.tb10719.x  0.364
1999 Fuxe K, Jansson A, Diaz-Cabiale Z, Andersson A, Tinner B, Finnman UB, Misane I, Razani H, Wang FH, Agnati LF, Ogren SO. Galanin modulates 5-hydroxytryptamine functions. Focus on galanin and galanin fragment/5-hydroxytryptamine1A receptor interactions in the brain. Annals of the New York Academy of Sciences. 863: 274-90. PMID 9928178 DOI: 10.1111/j.1749-6632.1998.tb10702.x  0.442
1999 Rinken A, Finnman U, Fuxe K. Pharmacological characterization of dopamine-stimulated [35S]-guanosine 5'-(γ-thiotriphosphate) ([35S]GTPγS) binding in rat striatal membranes Biochemical Pharmacology. 57: 155-162. PMID 9890563 DOI: 10.1016/S0006-2952(98)00287-1  0.407
1999 Morari M, Marti M, Sbrenna S, Fuxe K, Bianchi C, Beani L. Reciprocal dopamine-glutamate modulation of release in the basal ganglia. Neurochemistry International. 33: 383-97. PMID 9874089 DOI: 10.1016/S0197-0186(98)00052-7  0.43
1998 Caberlotto L, Fuxe K, Overstreet DH, Gerrard P, Hurd YL. Alterations in neuropeptide Y and Y1 receptor mRNA expression in brains from an animal model of depression: region specific adaptation after fluoxetine treatment. Brain Research. Molecular Brain Research. 59: 58-65. PMID 9729278 DOI: 10.1016/S0169-328X(98)00137-5  0.344
1998 Popoli P, Reggio R, Pèzzola A, Fuxe K, Ferré S. Adenosine A1 and A2A receptor antagonists stimulate motor activity: evidence for an increased effectiveness in aged rats Neuroscience Letters. 251: 201-204. PMID 9726378 DOI: 10.1016/S0304-3940(98)00533-3  0.358
1998 Jansson A, Tinner B, Steinbusch HWM, Agnati LF, Fuxe K. On the relationship of 5-hydroxytryptamine neurons to 5-hydroxytryptamine 2A receptor-immunoreactive neuronal processes in the brain stem of rats. A double immunolabelling analysis Neuroreport. 9: 2505-2511. PMID 9721923 DOI: 10.1097/00001756-199808030-00015  0.311
1998 Caberlotto L, Fuxe K, Rimland JM, Sedvall G, Hurd YL. Regional distribution of neuropeptide Y Y2 receptor messenger RNA in the human post mortem brain. Neuroscience. 86: 167-78. PMID 9692752 DOI: 10.1016/S0306-4522(98)00039-6  0.358
1998 Caberlotto L, Tinner B, Bunnemann B, Agnati L, Fuxe K. On the relationship of neuropeptide Y Y1 receptor-immunoreactive neuronal structures to the neuropeptide Y-immunoreactive nerve terminal networks. A double immunolabelling analysis in the rat brain. Neuroscience. 86: 827-845. PMID 9692720 DOI: 10.1016/S0306-4522(98)00089-X  0.415
1998 Chadi G, Fuxe K. Analysis of trophic responses in lesioned brain: focus on basic fibroblast growth factor mechanisms Brazilian Journal of Medical and Biological Research. 31: 231-241. PMID 9686146 DOI: 10.1590/S0100-879X1998000200007  0.306
1998 Fior-Chadi DR, Fuxe K. Quantitative Receptor Radioautography In The Study Of Receptor-Receptor Interactions In The Nucleus Tractus Solitarii Brazilian Journal of Medical and Biological Research. 31: 225-230. PMID 9686145 DOI: 10.1590/S0100-879X1998000200006  0.422
1998 Hansson AC, Andersson A, Tinner B, Cui X, Sommer W, Fuxe K. Existence of striatal nerve cells coexpressing CCKB and D2 receptor mRNAs Neuroreport. 9: 2035-2038. PMID 9674589 DOI: 10.1097/00001756-199806220-00023  0.398
1998 Rimondini R, Ferré S, Giménez-Llort L, Ögren SO, Fuxe K. Differential effects of selective adenosine A1 and A2A receptor agonists on dopamine receptor agonist-induced behavioural responses in rats. European Journal of Pharmacology. 347: 153-158. PMID 9653875 DOI: 10.1016/S0014-2999(98)00107-1  0.481
1998 Fuxe K, Ferré S, Zoli M, Agnati LF. Integrated events in central dopamine transmission as analyzed at multiple levels. Evidence for intramembrane adenosine A2A/dopamine D2 and adenosine A1/dopamine D1 receptor interactions in the basal ganglia. Brain Research. Brain Research Reviews. 26: 258-73. PMID 9651540 DOI: 10.1016/S0165-0173(97)00049-0  0.459
1998 Zoli M, Torri C, Ferrari R, Jansson A, Zini I, Fuxe K, Agnati LF. The emergence of the volume transmission concept. Brain Research. Brain Research Reviews. 26: 136-47. PMID 9651506 DOI: 10.1016/S0165-0173(97)00048-9  0.336
1998 Popoli P, Betto P, Rimondini R, Reggio R, Pézzola A, Ricciarello G, Fuxe K, Ferré S. Age-related alteration of the adenosine/dopamine balance in the rat striatum Brain Research. 795: 297-300. PMID 9622656 DOI: 10.1016/S0006-8993(98)00356-4  0.44
1998 Sommer W, Cui X, Erdmann B, Wiklund L, Bricca G, Heilig M, Fuxe K. The spread and uptake pattern of intracerebrally administered oligonucleotides in nerve and glial cell populations of the rat brain. Antisense & Nucleic Acid Drug Development. 8: 75-85. PMID 9593045 DOI: 10.1089/Oli.1.1998.8.75  0.322
1998 Ferré S, Torvinen M, Antoniou K, Irenius E, Civelli O, Arenas E, Fredholm BB, Fuxe K. Adenosine A1 receptor-mediated modulation of dopamine D1 receptors in stably cotransfected fibroblast cells. The Journal of Biological Chemistry. 273: 4718-24. PMID 9468534 DOI: 10.1074/Jbc.273.8.4718  0.63
1998 Picciotto MR, Zoli M, Rimondini R, Léna C, Marubio LM, Pich EM, Fuxe K, Changeux JP. Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine. Nature. 391: 173-7. PMID 9428762 DOI: 10.1038/34413  0.35
1998 Ferraro L, Antonelli T, O’Connor WT, Fuxe K, Soubrié P, Tanganelli S. The striatal neurotensin receptor modulates striatal and pallidal glutamate and GABA release: functional evidence for a pallidal glutamate-GABA interaction via the pallidal-subthalamic nucleus loop. The Journal of Neuroscience. 18: 6977-6989. DOI: 10.1523/Jneurosci.18-17-06977.1998  0.344
1998 Belluardo N, Blum M, Mudo G, Fuxe K. Nicotine and nicotinic receptors in neuronal injury. Focus on basic FGF mechanisms European Neuropsychopharmacology. 8. DOI: 10.1016/S0924-977X(98)80117-X  0.309
1998 Fuxe K, Hökfelt T. Menek Goldstein (1926–1997) Trends in Pharmacological Sciences. 19: 1. DOI: 10.1016/S0165-6147(97)01145-0  0.39
1997 Lepiku M, Rinken A, Järv J, Fuxe K. Modulation of [3H]quinpirole binding to dopaminergic receptors by adenosine A2A receptors Neuroscience Letters. 239: 61-64. PMID 9469656 DOI: 10.1016/S0304-3940(97)00874-4  0.398
1997 Razani H, Hedlund PB, Hansson AC, Fuxe K, Ögren SO. 5-HT1A receptor activation: short-term effects on the mRNA expression of the 5-HT1A receptor and galanin in the raphe nuclei. Neuroreport. 8: 3565-3569. PMID 9427327 DOI: 10.1097/00001756-199711100-00029  0.411
1997 Ferraro L, Antonelli T, O'Connor WT, Tanganelli S, Rambert FA, Fuxe K. Modafinil: an antinarcoleptic drug with a different neurochemical profile to d-amphetamine and dopamine uptake blockers. Biological Psychiatry. 42: 1181-3. PMID 9426889 DOI: 10.1016/S0006-3223(97)00353-3  0.346
1997 Ferraro L, O'Connor WT, Antonelli T, Fuxe K, Tanganelli S. Differential effects of intrastriatal neurotensin(1-13) and neurotensin(8-13) on striatal dopamine and pallidal GABA release. A dual-probe microdialysis study in the awake rat. The European Journal of Neuroscience. 9: 1838-46. PMID 9383206 DOI: 10.1111/J.1460-9568.1997.Tb00750.X  0.435
1997 Ferraro L, Antonelli T, O'Connor WT, Tanganelli S, Rambert F, Fuxe K. The antinarcoleptic drug modafinil increases glutamate release in thalamic areas and hippocampus. Neuroreport. 8: 2883-7. PMID 9376524 DOI: 10.1097/00001756-199709080-00016  0.316
1997 Ferré S, Fredholm BB, Morelli M, Popoli P, Fuxe K. Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia. Trends in Neurosciences. 20: 482-7. PMID 9347617 DOI: 10.1016/S0166-2236(97)01096-5  0.694
1997 Yang SN, Lippoldt A, Jansson A, Phillips MI, Ganten D, Fuxe K. Localization of angiotensin II AT1 receptor-like immunoreactivity in catecholaminergic neurons of the rat medulla oblongata. Neuroscience. 81: 503-15. PMID 9300437 DOI: 10.1016/S0306-4522(97)00057-2  0.386
1997 Diaz R, Fuxe K, Ögren SO. Prenatal corticosterone treatment induces long-term changes in spontaneous and apomorphine-mediated motor activity in male and female rats Neuroscience. 81: 129-140. PMID 9300406 DOI: 10.1016/S0306-4522(97)00141-3  0.353
1997 Ogren SO, Ferré S, Schwarcz R, Fuxe K. Prolonged treatment with haloperidol and clozapine in the rat: differential effects on spontaneous and theophylline-induced motor activity. Neuroscience Letters. 232: 21-4. PMID 9292882 DOI: 10.1016/S0304-3940(97)00564-8  0.435
1997 Janson AM, Fuxe K. Chronic Nicotine Treatment Differentially Regulates Substance P and Tyrosine Hydroxylase Immunoreactivity in Substantia Nigra Ipsilateral to a Unilateral Lesion Experimental Neurology. 146: 575-586. PMID 9270071 DOI: 10.1006/Exnr.1997.6562  0.338
1997 Bhatnagar M, Cintra A, Chadi G, Lindberg J, Oitzl M, De Kloet ER, Möller A, Agnati LF, Fuxe K. Neurochemical changes in the hippocampus of the brown Norway rat during aging. Neurobiology of Aging. 18: 319-27. PMID 9263198 DOI: 10.1016/S0197-4580(97)80314-4  0.493
1997 Sommer W, Fuxe K. On the role of c-fos expression in striatal transmission. The antisense oligonucleotide approach Neurochemistry International. 31: 425-436. PMID 9246684 DOI: 10.1016/S0197-0186(96)00112-X  0.303
1997 Pérez de la Mora M, Ferré S, Fuxe K. GABA-dopamine receptor-receptor interactions in neostriatal membranes of the rat. Neurochemical Research. 22: 1051-4. PMID 9239761 DOI: 10.1023/A:1022439212836  0.465
1997 Li X, Jansson A, Finnman U, Agnati LF, Fuxe K. Possible involvement of G-proteins in the regulation of striatal dopamine D2 receptor affinity by cholecystokinin octapeptide Neuroscience Letters. 228: 171-174. PMID 9218635 DOI: 10.1016/S0304-3940(97)00392-3  0.369
1997 Caberlotto L, Fuxe K, Sedvall G, Hurd YL. Localization of neuropeptide Y Y1 mRNA in the human brain: abundant expression in cerebral cortex and striatum. The European Journal of Neuroscience. 9: 1212-25. PMID 9215705 DOI: 10.1111/J.1460-9568.1997.Tb01476.X  0.362
1997 Odagaki Y, Fuxe K. Agonist-induced high-affinity GTP hydrolysis as an index of receptor-mediated G protein activation in mammalian brain membranes. Methods of Molecular Biology. 83: 133-142. PMID 9210142 DOI: 10.1385/0-89603-495-X:133  0.358
1997 Diaz R, Sokoloff P, Fuxe K. Codistribution of the dopamine D3 receptor and glucocorticoid receptor mRNAs during striatal prenatal development in the rat. Neuroscience Letters. 227: 119-122. PMID 9180218 DOI: 10.1016/S0304-3940(97)00316-9  0.448
1997 Yang SN, Fior DR, Hansson AC, Cintra A, Castellano M, Ganten U, Ganten D, Agnati LF, Fuxe K. Increased potency of neuropeptide Y to antagonize alpha2-adrenoceptor function in the nucleus tractus solitarii of the spontaneously hypertensive rat. Neuroscience. 78: 803-13. PMID 9153659 DOI: 10.1016/S0306-4522(96)00487-3  0.336
1997 Lepiku M, Järv J, Rinken A, Fuxe K. Mechanism of modulation of [3H]raclopride binding to dopaminergic receptors in rat striatal membranes by sodium ions Neurochemistry International. 30: 575-581. PMID 9152999 DOI: 10.1016/S0197-0186(96)00121-0  0.37
1997 Fuxe K, Tinner B, Caberlotto L, Bunnemann B, Agnati LF. NPY Y1 receptor like immunoreactivity exists in a subpopulation of β-endorphin immunoreactive nerve cells in the arcuate nucleus: a double immunolabelling analysis in the rat Neuroscience Letters. 225: 49-52. PMID 9143015 DOI: 10.1016/S0304-3940(97)00184-5  0.386
1997 Belluardo N, Wu G, Mudo G, Hansson AC, Pettersson R, Fuxe K. Comparative localization of fibroblast growth factor receptor-1, -2, and -3 mRNAs in the rat brain: in situ hybridization analysis. The Journal of Comparative Neurology. 379: 226-246. PMID 9050787 DOI: 10.1002/(Sici)1096-9861(19970310)379:2<226::Aid-Cne5>3.0.Co;2-5  0.339
1997 Fuxe K, Tinner B, Staines W, David G, Agnati LF. Regional distribution of neural cell adhesion molecule immunoreactivity in the adult rat telencephalon and diencephalon. Partial colocalization with heparan sulfate proteoglycan immunoreactivity. Brain Research. 746: 25-33. PMID 9037480 DOI: 10.1016/S0006-8993(96)01130-4  0.306
1996 FUXE K, HOEKFELT T, NILSSON O. OBSERVATIONS ON THE CELLULAR LOCALIZATION OF DOPAMINE IN THE CAUDATE NUCLEUS OF THE RAT. Zeitschrift Fur Zellforschung Und Mikroskopische Anatomie (Vienna, Austria : 1948). 63: 701-6. PMID 14254762 DOI: 10.1007/BF00339917  0.357
1996 DAHLSTROEM A, FUXE K, OLSON L, UNGERSTEDT U. ASCENDING SYSTEMS OF CATECHOLAMINE NEURONS FROM THE LOWER BRAIN STEM. Acta Physiologica Scandinavica. 62: 485-6. PMID 14252583 DOI: 10.1111/J.1748-1716.1964.TB10446.X  0.567
1996 Bjelke B, Goldstein M, Tinner B, Andersson C, Sesack SR, Steinbusch HW, Lew JY, He X, Watson S, Tengroth B, Fuxe K. Dopaminergic transmission in the rat retina: evidence for volume transmission. Journal of Chemical Neuroanatomy. 12: 37-50. PMID 9001947 DOI: 10.1016/S0891-0618(96)00176-7  0.4
1996 Diaz Z, Narváez J, Hedlund PB, Aguirre J, González-Barón S, Fuxe K. Centrally infused galanin-(1–15) but not galanin-(1–29) reduces the baroreceptor reflex sensitivity in the rat Brain Research. 741: 32-37. PMID 9001701 DOI: 10.1016/S0006-8993(96)00883-9  0.303
1996 Dasgupta S, Ferré S, Kull B, Hedlund PB, Finnman UB, Ahlberg S, Arenas E, Fredholm BB, Fuxe K. Adenosine A2A receptors modulate the binding characteristics of dopamine D2 receptors in stably cotransfected fibroblast cells. European Journal of Pharmacology. 316: 325-31. PMID 8982704 DOI: 10.1016/S0014-2999(96)00665-6  0.681
1996 Yang S, Finnman U, Fuxe K. The non-peptide neuropeptide Y Y1 receptor antagonist BIBP3226 blocks the [Leu31, Pro34]neuropeptide Y-induced modulation of α2-adrenoceptors in the nucleus tractus solitarii of the rat Neuroreport. 7: 2701-2705. PMID 8981451 DOI: 10.1097/00001756-199611040-00059  0.421
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