Rajesh Khanna - Publications

Pharmacology & Toxicology Indiana University School of Medicine, Indianapolis, IN, United States 
biogenesis, trafficking and quality control of ion channels

146 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Rodriguez-Palma EJ, Allen HN, Khanna R. STINGing away the pain: the role of interferon-stimulated genes. The Journal of Clinical Investigation. 134. PMID 38690736 DOI: 10.1172/JCI180497  0.303
2024 Goldstein N, Maes A, Allen HN, Nelson TS, Kruger KA, Kindel M, Smith NK, Carty JRE, Villari RE, Cho E, Marble EL, Khanna R, Taylor BK, Kennedy A, Betley JN. A parabrachial hub for the prioritization of survival behavior. Biorxiv : the Preprint Server For Biology. PMID 38464066 DOI: 10.1101/2024.02.26.582069  0.739
2023 Gomez K, Santiago U, Nelson TS, Allen HN, Calderon-Rivera A, Hestehave S, Rodríguez Palma EJ, Zhou Y, Duran P, Loya-Lopez S, Zhu E, Kumar U, Shields R, Koseli E, McKiver B, ... ... Khanna R, et al. A peptidomimetic modulator of the Ca2.2 N-type calcium channel for chronic pain. Proceedings of the National Academy of Sciences of the United States of America. 120: e2305215120. PMID 37972067 DOI: 10.1073/pnas.2305215120  0.696
2023 Gomez K, Allen HN, Duran P, Loya-Lopez S, Calderon-Rivera A, Moutal A, Tang C, Nelson TS, Perez-Miller S, Khanna R. Targeted transcriptional upregulation of SENP1 by CRISPR activation enhances deSUMOylation pathways to elicit antinociception in the spinal nerve ligation model of neuropathic pain. Pain. PMID 37862053 DOI: 10.1097/j.pain.0000000000003080  0.717
2023 Loya-Lopez SI, Allen HN, Duran P, Calderon-Rivera A, Gomez K, Kumar U, Shields R, Zeng R, Dwivedi A, Saurabh S, Korczeniewska OA, Khanna R. Intranasal CRMP2-Ubc9 inhibitor regulates NaV1.7 to alleviate trigeminal neuropathic pain. Pain. PMID 37751532 DOI: 10.1097/j.pain.0000000000003053  0.39
2023 Loya-Lopez SI, Allen HN, Duran P, Calderon-Rivera A, Gomez K, Kumar U, Shields R, Zeng R, Dwivedi A, Saurabh S, Korczeniewska OA, Khanna R. Intranasal CRMP2-Ubc9 Inhibitor Regulates Na 1.7 to Alleviate Trigeminal Neuropathic Pain. Biorxiv : the Preprint Server For Biology. PMID 37502910 DOI: 10.1101/2023.07.16.549195  0.364
2023 Gomez K, Duran P, Tonello R, Allen HN, Boinon L, Calderon-Rivera A, Loya-López S, Nelson TS, Ran D, Moutal A, Bunnett NW, Khanna R. Neuropilin-1 is essential for vascular endothelial growth factor A-mediated increase of sensory neuron activity and development of pain-like behaviors. Pain. PMID 37366599 DOI: 10.1097/j.pain.0000000000002970  0.719
2023 Nelson TS, Khanna R. The Emerging Translational Potential of MNK Inhibitors for the Treatment of Chronic Pain. Neuroscience. 515: 93-95. PMID 36922084 DOI: 10.1016/j.neuroscience.2023.02.009  0.659
2023 Calderon-Rivera A, Gomez K, Loya-López S, Wijeratne EMK, Stratton H, Tang C, Duran P, Masterson K, Alsbiei O, Gunatilaka AAL, Khanna R. Betulinic acid analogs inhibit N- and T-type voltage-gated calcium channels to attenuate nerve-injury associated neuropathic and formalin models of pain. Neurobiology of Pain (Cambridge, Mass.). 13: 100116. PMID 36687466 DOI: 10.1016/j.ynpai.2023.100116  0.353
2022 Stratton HJ, Boinon L, Gomez K, Martin L, Duran P, Ran D, Zhou Y, Luo S, Perez-Miller S, Patek M, Ibrahim MM, Patwardhan A, Moutal A, Khanna R. Targeting the vascular endothelial growth factor A/neuropilin 1 axis for relief of neuropathic pain. Pain. PMID 36729125 DOI: 10.1097/j.pain.0000000000002850  0.323
2022 Loya-López SI, Duran P, Ran D, Calderon-Rivera A, Gomez K, Moutal A, Khanna R. Cell specific regulation of NaV1.7 activity and trafficking in rat nodose ganglia neurons. Neurobiology of Pain (Cambridge, Mass.). 12: 100109. PMID 36531612 DOI: 10.1016/j.ynpai.2022.100109  0.388
2022 Duran P, Loya-López S, Ran D, Tang C, Calderon-Rivera A, Gomez K, Stratton HJ, Huang S, Xu YM, Wijeratne EMK, Perez-Miller S, Shan Z, Cai S, Gabrielsen AT, Dorame A, ... ... Khanna R, et al. The natural product Argentatin C attenuates postoperative pain via inhibition of voltage-gated sodium and T-type voltage-gated calcium channels. British Journal of Pharmacology. PMID 36245395 DOI: 10.1111/bph.15974  0.314
2022 Gomez K, Tang C, Tan B, Perez-Miller S, Ran D, Loya S, Calderon-Rivera A, Stratton HJ, Duran P, Masterson KA, Gabrielsen AT, Alsbiei O, Dorame A, Serafini M, Moutal A, ... ... Khanna R, et al. Stereospecific Effects of Benzimidazolonepiperidine Compounds on T-Type Ca Channels and Pain. Acs Chemical Neuroscience. PMID 35671441 DOI: 10.1021/acschemneuro.2c00256  0.334
2022 Kong X, Li Y, Perez-Miller S, Luo G, Liao Q, Wu X, Liang S, Tang C, Khanna R, Liu Z. The small molecule compound C65780 alleviates pain by stabilizing voltage-gated sodium channels in the inactivated and slowly-recovering state. Neuropharmacology. 109057. PMID 35413303 DOI: 10.1016/j.neuropharm.2022.109057  0.33
2022 Goins AE, Gomez K, Ran D, Afaghpour-Becklund M, Khanna R, Alles SRA. Neuronal allodynic mechanisms of Slc7a5 (LAT1) in the spared nerve injury rodent model of neuropathic pain. Pflugers Archiv : European Journal of Physiology. PMID 35048187 DOI: 10.1007/s00424-021-02653-9  0.368
2022 Boinon L, Yu J, Madura CL, Chefdeville A, Feinstein DL, Moutal A, Khanna R. Conditional knockout of CRMP2 in neurons, but not astrocytes, disrupts spinal nociceptive neurotransmission to control the initiation and maintenance of chronic neuropathic pain. Pain. 163: e368-e381. PMID 35029600 DOI: 10.1097/j.pain.0000000000002344  0.358
2022 Braden K, Stratton HJ, Salvemini D, Khanna R. Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces and prevents pain chronification in a mouse model of oxaliplatin-induced neuropathic pain. Neurobiology of Pain (Cambridge, Mass.). 11: 100082. PMID 35024498 DOI: 10.1016/j.ynpai.2021.100082  0.335
2022 Li J, Stratton HJ, Lorca SA, Grace PM, Khanna R. Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in chronic constriction injury (CCI) rats. Channels (Austin, Tex.). 16: 1-8. PMID 34983286 DOI: 10.1080/19336950.2021.2023383  0.354
2021 Martin L, Ibrahim M, Gomez K, Yu J, Cai S, Chew LA, Bellampalli SS, Moutal A, Largent-Milnes T, Porreca F, Khanna R, Olivera BM, Patwardhan A. Conotoxin contulakin-G engages a neurotensin receptor 2 /R-type calcium channel (Cav2.3) pathway to mediate spinal antinociception. Pain. PMID 35050960 DOI: 10.1097/j.pain.0000000000002561  0.326
2021 Gomez K, Ran D, Madura CL, Moutal A, Khanna R. Non-SUMOylated CRMP2 decreases Na1.7 currents via the endocytic proteins Numb, Nedd4-2 and Eps15. Molecular Brain. 14: 20. PMID 33478555 DOI: 10.1186/s13041-020-00714-1  0.329
2021 Cai S, Gomez K, Moutal A, Khanna R. Targeting T-type/CaV3.2 channels for chronic pain. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 33422652 DOI: 10.1016/j.trsl.2021.01.002  0.379
2021 Ran D, Gomez K, Moutal A, Patek M, Perez-Miller S, Khanna R. Comparison of quinazoline and benzoylpyrazoline chemotypes targeting the CaVα-β interaction as antagonists of the N-type CaV2.2 channel. Channels (Austin, Tex.). 15: 128-135. PMID 33416017 DOI: 10.1080/19336950.2020.1863595  0.302
2020 Schulien AJ, Yeh CY, Orange BN, Pav OJ, Hopkins MP, Moutal A, Khanna R, Sun D, Justice JA, Aizenman E. Targeted disruption of Kv2.1-VAPA association provides neuroprotection against ischemic stroke in mice by declustering Kv2.1 channels. Science Advances. 6. PMID 32937450 DOI: 10.1126/Sciadv.Aaz8110  0.336
2020 Gomez K, Vallecillo TGM, Moutal A, Perez-Miller S, Delgado-Lezama R, Felix R, Khanna R. The role of cyclin dependent kinase 5 (Cdk5) in neuropathic pain. Pain. PMID 32773603 DOI: 10.1097/J.Pain.0000000000002027  0.463
2020 Alles SRA, Gomez K, Moutal A, Khanna R. Putative roles of SLC7A5 (LAT1) transporter in pain. Neurobiology of Pain (Cambridge, Mass.). 8: 100050. PMID 32715162 DOI: 10.1016/J.Ynpai.2020.100050  0.453
2020 Khanna R, Moutal A, Perez-Miller S, Chefdeville A, Boinon L, Patek M. Druggability of CRMP2 for neurodegenerative diseases. Acs Chemical Neuroscience. PMID 32693579 DOI: 10.1021/Acschemneuro.0C00307  0.381
2020 Janakiraman U, Dhanalakshmi C, Yu J, Moutal A, Boinon L, Fukunaga K, Khanna R, Nelson MA. The investigation of the T-type calcium channel enhancer SAK3 in an animal model of TAF1 intellectual disability syndrome. Neurobiology of Disease. 143: 105006. PMID 32622085 DOI: 10.1016/J.Nbd.2020.105006  0.332
2020 Moutal A, Ji Y, Bellampalli SS, Khanna R. Differential expression of Cdk5-phosphorylated CRMP2 following a spared nerve injury. Molecular Brain. 13: 97. PMID 32571373 DOI: 10.1186/S13041-020-00633-1  0.441
2020 Moutal A, Cai S, Yu J, Stratton HJ, Chefdeville A, Gomez K, Ran D, Madura CL, Boinon L, Soto M, Zhou Y, Shan Z, Chew LA, Rodgers KE, Khanna R. Studies on CRMP2 SUMOylation-deficient transgenic mice identify sex-specific NaV1.7 regulation in the pathogenesis of chronic neuropathic pain. Pain. PMID 32569093 DOI: 10.1097/J.Pain.0000000000001951  0.447
2020 Cai S, Tuohy P, Ma C, Kitamura N, Gomez K, Zhou Y, Ran D, Bellampalli SS, Yu J, Luo S, Dorame A, Ngan Pham NY, Molnar G, Streicher JM, Patek M, ... ... Khanna R, et al. A modulator of the low-voltage activated T-type calcium channel that reverses HIV glycoprotein 120-, paclitaxel-, and spinal nerve ligation-induced peripheral neuropathies. Pain. PMID 32541387 DOI: 10.1097/J.Pain.0000000000001955  0.427
2020 Stratton H, Boinon L, Moutal A, Khanna R. Coordinating Synaptic Signaling with CRMP2. The International Journal of Biochemistry & Cell Biology. 105759. PMID 32437854 DOI: 10.1016/J.Biocel.2020.105759  0.336
2020 Zhou Y, Cai S, Gomez K, Wijeratne EMK, Ji Y, Bellampalli SS, Luo S, Moutal A, Gunatilaka AAL, Khanna R. 1-O-Acetylgeopyxin A, a derivative of a fungal metabolite, blocks tetrodotoxin-sensitive voltage-gated sodium, calcium channels and neuronal excitability which correlates with inhibition of neuropathic pain. Molecular Brain. 13: 73. PMID 32393368 DOI: 10.1186/S13041-020-00616-2  0.465
2020 Qi B, Yang Y, Cheng Y, Sun D, Wang X, Khanna R, Ju W. Nasal delivery of a CRMP2-derived CBD3 adenovirus improves cognitive function and pathology in APP/PS1 transgenic mice. Molecular Brain. 13: 58. PMID 32272942 DOI: 10.1186/S13041-020-00596-3  0.319
2020 Chen Y, Moutal A, Navratilova E, Kopruszinski C, Yue X, Ikegami M, Chow M, Kanazawa I, Bellampalli SS, Xie J, Patwardhan A, Rice K, Fields H, Akopian A, Neugebauer V, ... ... Khanna R, et al. The prolactin receptor long isoform regulates nociceptor sensitization and opioid-induced hyperalgesia selectively in females. Science Translational Medicine. 12. PMID 32024801 DOI: 10.1126/Scitranslmed.Aay7550  0.332
2019 de Macedo FHP, Aires RD, Fonseca EG, Ferreira RCM, Machado DPD, Chen L, Zhang FX, Souza IA, Lemos VS, Romero TRL, Moutal A, Khanna R, Zamponi GW, Cruz JS. TNF-α mediated upregulation of Na1.7 currents in rat dorsal root ganglion neurons is independent of CRMP2 SUMOylation. Molecular Brain. 12: 117. PMID 31888677 DOI: 10.1186/S13041-019-0538-0  0.364
2019 Khanna R, Patwardhan A, Yang X, Li W, Cai S, Ji Y, Chew LA, Dorame A, Bellampalli SS, Schmoll RW, Gordon J, Moutal A, Vanderah TW, Porreca F, Ibrahim MM. Erratum to ‛Development and Characterization of An Injury-free Model of Functional Pain in Rats by Exposure to Red Light': The Journal of Pain 20 (2019) 1293-1306. The Journal of Pain : Official Journal of the American Pain Society. 20: 1509. PMID 31818395 DOI: 10.1016/J.Jpain.2019.11.012  0.351
2019 Jin Y, Cai S, Jiang Y, Zhong K, Wen C, Ruan Y, Chew LA, Khanna R, Xu Z, Yu J. Tetramethylpyrazine reduces epileptogenesis progression in electrical kindling models by modulating hippocampal excitatory neurotransmission. Acs Chemical Neuroscience. PMID 31756074 DOI: 10.1021/Acschemneuro.9B00575  0.328
2019 Zhou Y, Cai S, Moutal A, Yu J, Gomez K, Madura CL, Shan Z, Ngan Pham NY, Serafini MJ, Dorame A, Scott DD, Francois-Moutal L, Perez-Miller S, Patek M, Khanna M, ... Khanna R, et al. The natural flavonoid Naringenin elicits analgesia through inhibition of NaV1.8 voltage-gated sodium channels. Acs Chemical Neuroscience. PMID 31697467 DOI: 10.1021/Acschemneuro.9B00547  0.455
2019 Moutal A, Shan Z, Miranda VG, François-Moutal L, Madura CL, Khanna M, Khanna R. Evaluation of edonerpic maleate as a CRMP2 inhibitor for pain relief. Channels (Austin, Tex.). 13: 498-504. PMID 31680630 DOI: 10.1080/19336950.2019.1684608  0.476
2019 Janakiraman U, Yu J, Moutal A, Raman DS, Boinon L, Batchelor SN, Annadurai A, Khanna R, Nelson MA. TAF1-gene editing alters the morphology and function of the cerebellum. Neurobiology of Disease. 104539. PMID 31344492 DOI: 10.1016/J.Nbd.2019.104539  0.322
2019 Yeh CY, Ye Z, Moutal A, Gaur S, Henton AM, Kouvaros S, Saloman JL, Hartnett-Scott KA, Tzounopoulos T, Khanna R, Aizenman E, Camacho CJ. Defining the Kv2.1-syntaxin molecular interaction identifies a first-in-class small molecule neuroprotectant. Proceedings of the National Academy of Sciences of the United States of America. PMID 31308225 DOI: 10.1073/Pnas.1903401116  0.381
2019 Khanna R, Moutal A, White KA, Chefdeville A, Negrao de Assis P, Cai S, Swier VJ, Bellampalli SS, Giunta MD, Darbro BW, Quelle DE, Sieren JC, Wallace MR, Rogers CS, Meyerholz DK, et al. Assessment of nociception and related quality of life measures in a porcine model of Neurofibromatosis type 1. Pain. PMID 31246731 DOI: 10.1097/J.Pain.0000000000001648  0.403
2019 Yu H, Shin SM, Xiang H, Chao D, Cai Y, Xu H, Khanna R, Pan B, Hogan QH. AAV-encoded Ca2.2 peptide aptamer CBD3A6K for primary sensory neuron-targeted treatment of established neuropathic pain. Gene Therapy. PMID 31118475 DOI: 10.1038/S41434-019-0082-7  0.489
2019 Moutal A, Luo S, Largent-Milnes TM, Vanderah TW, Khanna R. Cdk5-mediated CRMP2 phosphorylation is necessary and sufficient for peripheral neuropathic pain. Neurobiology of Pain (Cambridge, Mass.). 5. PMID 31080913 DOI: 10.1016/J.Ynpai.2018.07.003  0.444
2019 Khanna R, Patwardhan A, Yang X, Li W, Cai S, Ji Y, Chew LA, Dorame A, Bellampalli SS, Schmoll RW, Gordon J, Moutal A, Vanderah TW, Porreca F, Ibrahim MM. Development and Characterization of An Injury-free Model of Functional Pain in Rats by Exposure to Red Light. The Journal of Pain : Official Journal of the American Pain Society. PMID 31054915 DOI: 10.1016/J.Jpain.2019.04.008  0.371
2019 Cai S, Shan Z, Zhang Z, Moutal A, Khanna R. Activity of T-type calcium channels is independent of CRMP2 in sensory neurons. Channels (Austin, Tex.). 13: 147-152. PMID 31025580 DOI: 10.1080/19336950.2019.1608129  0.409
2019 Bellampalli SS, Khanna R. Towards a neurobiological understanding of pain in neurofibromatosis type 1: mechanisms and implications for treatment. Pain. 160: 1007-1018. PMID 31009417 DOI: 10.1097/J.Pain.0000000000001486  0.379
2019 Shan Z, Cai S, Yu J, Zhang Z, Vallecillo TGM, Serafini MJ, Thomas AM, Pham NYN, Bellampalli SS, Moutal A, Zhou Y, Xu GB, Xu YM, Luo S, Patek M, ... ... Khanna R, et al. Reversal of peripheral neuropathic pain by the small-molecule natural product physalin F via block of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels. Acs Chemical Neuroscience. PMID 30946560 DOI: 10.1021/Acschemneuro.9B00166  0.444
2019 Khanna R, Yu J, Yang X, Moutal A, Chefdeville A, Gokhale V, Shuja Z, Chew LA, Bellampalli SS, Luo S, François-Moutal L, Serafini MJ, Ha T, Perez-Miller S, Park KD, et al. Targeting the CaVα-CaVβ interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacy. Pain. PMID 30933958 DOI: 10.1097/J.Pain.0000000000001524  0.471
2019 Moutal A, White KA, Chefdeville A, Laufmann RN, Vitiello PF, Feinstein D, Weimer JM, Khanna R. Dysregulation of CRMP2 Post-Translational Modifications Drive Its Pathological Functions. Molecular Neurobiology. PMID 30915713 DOI: 10.1007/S12035-019-1568-4  0.366
2019 Ji Y, Hu Y, Ren J, Khanna R, Yao Y, Chen Y, Li Q, Sun L. CRMP2-derived peptide ST2-104 (R9-CBD3) protects SH-SY5Y neuroblastoma cells against Aβ-induced neurotoxicity by inhibiting the pCRMP2/NMDAR2B signaling pathway. Chemico-Biological Interactions. PMID 30871964 DOI: 10.1016/J.Cbi.2019.03.005  0.394
2019 Chew LA, Bellampalli SS, Dustrude ET, Khanna R. Mining the Na1.7 interactome: Opportunities for chronic pain therapeutics. Biochemical Pharmacology. 163: 9-20. PMID 30699328 DOI: 10.1016/J.Bcp.2019.01.018  0.442
2019 Moutal A, Dustrude ET, Largent-Milnes TM, Vanderah TW, Khanna M, Khanna R. Blocking CRMP2 SUMOylation reverses neuropathic pain. Molecular Psychiatry. 23: 2119-2121. PMID 28533518 DOI: 10.1038/Mp.2017.117  0.305
2018 Yu J, Moutal A, Dorame A, Bellampalli SS, Chefdeville A, Kanazawa I, Pham NYN, Park KD, Weimer JM, Khanna R. Phosphorylated CRMP2 Regulates Spinal Nociceptive Neurotransmission. Molecular Neurobiology. PMID 30565051 DOI: 10.1007/S12035-018-1445-6  0.418
2018 Cai S, Bellampalli SS, Yu J, Li W, Ji Y, Wijeratne EMK, Dorame A, Luo S, Shan Z, Khanna M, Moutal A, Streicher JM, Gunatilaka AAL, Khanna R. (-)-Hardwickiic acid and Hautriwaic acid induce antinociception via blockade of tetrodotoxin-sensitive voltage-dependent sodium channels. Acs Chemical Neuroscience. PMID 30525440 DOI: 10.1021/Acschemneuro.8B00617  0.459
2018 Quach TT, Auvergnon N, Khanna R, Belin MF, Kolattukudy PE, Honnorat J, Duchemin AM. Opposing Morphogenetic Defects on Dendrites and Mossy Fibers of Dentate Granular Neurons in CRMP3-Deficient Mice. Brain Sciences. 8. PMID 30400291 DOI: 10.3390/Brainsci8110196  0.331
2018 Alberio L, Locarno A, Saponaro A, Romano E, Bercier V, Albadri S, Simeoni F, Moleri S, Pelucchi S, Porro A, Marcello E, Barsotti N, Kukovetz K, Boender AJ, Contestabile A, ... ... Khanna R, et al. A light-gated potassium channel for sustained neuronal inhibition. Nature Methods. PMID 30377377 DOI: 10.1038/S41592-018-0186-9  0.423
2018 Chew LA, Khanna R. CRMP2 and voltage-gated ion channels: potential roles in neuropathic pain. Neuronal Signaling. 2. PMID 30364788 DOI: 10.1042/NS20170220  0.338
2018 Bellampalli SS, Ji Y, Moutal A, Cai S, Wijeratne EMK, Gandini MA, Yu J, Chefdeville A, Dorame A, Chew LA, Madura CL, Luo S, Molnar G, Khanna M, Streicher JM, ... ... Khanna R, et al. Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathy via block of N- and T-type calcium channels. Pain. PMID 30169422 DOI: 10.1097/J.Pain.0000000000001385  0.448
2018 François-Moutal L, Scott DD, Perez-Miller S, Gokhale V, Khanna M, Khanna R. Chemical shift perturbation mapping of the Ubc9-CRMP2 interface identifies a pocket in CRMP2 amenable for allosteric modulation of Nav1.7 channels. Channels (Austin, Tex.). 1-9. PMID 30081699 DOI: 10.1080/19336950.2018.1491244  0.461
2018 François-Moutal L, Dustrude ET, Wang Y, Brustovetsky T, Dorame A, Ju W, Moutal A, Perez-Miller S, Brustovetsky N, Gokhale V, Khanna M, Khanna R. Inhibition of the Ubc9 E2 SUMO conjugating enzyme-CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain. Pain. PMID 29847471 DOI: 10.1097/J.Pain.0000000000001294  0.456
2018 Moutal A, Sun L, Yang X, Li W, Cai S, Luo S, Khanna R. CRMP2 Neurofibromin Interface Drives NF1-related Pain. Neuroscience. PMID 29655575 DOI: 10.1016/J.Neuroscience.2018.04.002  0.411
2018 Parrilla-Carrero J, Buchta WC, Goswamee P, Culver O, McKendrick G, Harlan B, Moutal A, Penrod R, Khanna R, Kalivas P, Riegel AC. Restoration of Kv7 channel mediated inhibition reduces cued-reinstatement of cocaine seeking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29636392 DOI: 10.1523/Jneurosci.2767-17.2018  0.336
2017 Moutal A, Cai S, Luo S, Voisin R, Khanna R. CRMP2 is necessary for Neurofibromatosis type 1 related pain. Channels (Austin, Tex.). 0. PMID 28837387 DOI: 10.1080/19336950.2017.1370524  0.456
2017 Moutal A, Yang X, Li W, Gilbraith KB, Luo S, Cai S, François-Moutal L, Chew LA, Yeon SK, Bellampalli SS, Qu C, Xie JY, Ibrahim MM, Khanna M, Park KD, ... ... Khanna R, et al. CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide. Pain. PMID 28809766 DOI: 10.1097/J.Pain.0000000000001002  0.453
2017 Garami A, Ibrahim M, Gilbraith K, Khanna R, Pakai E, Miko A, Pinter E, Romanovsky AA, Porreca F, Patwardhan AM. Transient Receptor Potential Vanilloid 1 Antagonists Prevent Anesthesia-induced Hypothermia and Decrease Postincisional Opioid Dose Requirements in Rodents. Anesthesiology. PMID 28806222 DOI: 10.1097/Aln.0000000000001812  0.326
2017 Moutal A, Wang Y, Yang X, Ji Y, Luo S, Dorame A, Bellampalli SS, Chew LA, Cai S, Dustrude ET, Keener JE, Marty MT, Vanderah TW, Khanna R. Dissecting the role of the CRMP2-Neurofibromin complex on pain behaviors. Pain. PMID 28767512 DOI: 10.1097/J.Pain.0000000000001026  0.454
2017 Sandweiss AJ, McIntosh MI, Moutal A, Davidson-Knapp R, Hu J, Giri AK, Yamamoto T, Hruby VJ, Khanna R, Largent-Milnes TM, Vanderah TW. Genetic and pharmacological antagonism of NK1 receptor prevents opiate abuse potential. Molecular Psychiatry. PMID 28485408 DOI: 10.1038/Mp.2017.102  0.366
2017 Yeh CY, Bulas AM, Moutal A, Saloman JL, Hartnett KA, Anderson CT, Tzounopoulos T, Sun D, Khanna R, Aizenman E. Targeting a Potassium Channel/Syntaxin Interaction Ameliorates Cell Death in Ischemic Stroke. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28483976 DOI: 10.1523/Jneurosci.3811-16.2017  0.37
2017 Dustrude ET, Perez-Miller S, François-Moutal L, Moutal A, Khanna M, Khanna R. A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function. Channels (Austin, Tex.). 0. PMID 28277940 DOI: 10.1080/19336950.2017.1299838  0.317
2017 Moutal A, Li W, Wang Y, Ju W, Luo S, Cai S, François-Moutal L, Perez-Miller S, Hu J, Dustrude ET, Vanderah TW, Gokhale V, Khanna M, Khanna R. Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of CRMP2-derived peptides. British Journal of Pharmacology. PMID 28161890 DOI: 10.1111/Bph.13737  0.474
2017 Ibrahim MM, Patwardhan A, Gilbraith KB, Moutal A, Yang X, Chew LA, Largent-Milnes T, Malan TP, Vanderah TW, Porreca F, Khanna R. Long-lasting antinociceptive effects of green light in acute and chronic pain in rats. Pain. 158: 347-360. PMID 28092651 DOI: 10.1097/J.Pain.0000000000000767  0.396
2016 Dustrude ET, Moutal A, Yang X, Wang Y, Khanna M, Khanna R. Hierarchical CRMP2 posttranslational modifications control NaV1.7 function. Proceedings of the National Academy of Sciences of the United States of America. PMID 27940916 DOI: 10.1073/Pnas.1610531113  0.444
2016 Moutal A, Eyde N, Telemi E, Park KD, Xie JY, Dodick DW, Porreca F, Khanna R. Efficacy of (S)-Lacosamide in preclinical models of cephalic pain. Pain Reports (Baltimore, Md.). 1. PMID 27917413 DOI: 10.1097/PR9.0000000000000565  0.318
2016 Xie JY, Chew LA, Yang X, Wang Y, Qu C, Wang Y, Federici LM, Fitz SD, Ripsch MS, Due MR, Moutal A, Khanna M, White FA, Vanderah TW, Johnson PL, ... ... Khanna R, et al. Sustained relief of ongoing experimental neuropathic pain by a CRMP2 peptide aptamer with low abuse potential. Pain. 157: 2124-2140. PMID 27537210 DOI: 10.1097/J.Pain.0000000000000628  0.452
2016 Moutal A, Dustrude ET, Khanna R. Sensitization of Ion Channels Contributes to Central and Peripheral Dysfunction in Neurofibromatosis Type 1. Molecular Neurobiology. PMID 27167129 DOI: 10.1007/S12035-016-9907-1  0.322
2016 Moutal A, Chew LA, Yang X, Wang Y, Yeon SK, Telemi E, Meroueh S, Park KD, Shrinivasan R, Gilbraith KB, Qu C, Xie JY, Patwardhan A, Vanderah TW, Khanna M, ... ... Khanna R, et al. (S)-Lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology. Pain. PMID 26967696 DOI: 10.1097/J.Pain.0000000000000555  0.484
2015 Quach TT, Honnorat J, Kolattukudy PE, Khanna R, Duchemin AM. Collapsin response mediator protein 3 increases the dendritic arborization of hippocampal neurons. Molecular Psychiatry. 20: 1027. PMID 26293908 DOI: 10.1038/Mp.2015.123  0.329
2015 Shimomura A, Patel D, Wilson SM, Koehler KR, Khanna R, Hashino E. Tlx3 Promotes Glutamatergic Neuronal Subtype Specification through Direct Interactions with the Chromatin Modifier CBP. Plos One. 10: e0135060. PMID 26258652 DOI: 10.1371/Journal.Pone.0135060  0.345
2015 Quach TT, Honnorat J, Kolattukudy PE, Khanna R, Duchemin AM. CRMPs: critical molecules for neurite morphogenesis and neuropsychiatric diseases. Molecular Psychiatry. PMID 26077693 DOI: 10.1038/Mp.2015.77  0.427
2015 Torregrosa R, Yang XF, Dustrude ET, Cummins TR, Khanna R, Kohn H. Chimeric derivatives of functionalized amino acids and α-aminoamides: Compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels. Bioorganic & Medicinal Chemistry. 23: 3655-66. PMID 25922183 DOI: 10.1016/J.Bmc.2015.04.014  0.325
2015 Moutal A, François-Moutal L, Perez-Miller S, Cottier K, Chew LA, Yeon SK, Dai J, Park KD, Khanna M, Khanna R. (S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5. Molecular Neurobiology. PMID 25846820 DOI: 10.1007/S12035-015-9141-2  0.326
2015 François-Moutal L, Wang Y, Moutal A, Cottier KE, Melemedjian OK, Yang X, Wang Y, Ju W, Largent-Milnes TM, Khanna M, Vanderah TW, Khanna R. A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors. Pain. 156: 1247-64. PMID 25782368 DOI: 10.1097/j.pain.0000000000000147  0.328
2015 Park KD, Yang XF, Dustrude ET, Wang Y, Ripsch MS, White FA, Khanna R, Kohn H. Chimeric agents derived from the functionalized amino acid, lacosamide, and the α-aminoamide, safinamide: evaluation of their inhibitory actions on voltage-gated sodium channels, and antiseizure and antinociception activities and comparison with lacosamide and safinamide. Acs Chemical Neuroscience. 6: 316-30. PMID 25418676 DOI: 10.1021/Cn5002182  0.388
2015 Wilson SM, Khanna R. Specific binding of lacosamide to collapsin response mediator protein 2 (CRMP2) and direct impairment of its canonical function: implications for the therapeutic potential of lacosamide. Molecular Neurobiology. 51: 599-609. PMID 24944082 DOI: 10.1007/S12035-014-8775-9  0.352
2015 Shimomura A, Patel D, Wilson SM, Koehler KR, Khanna R, Hashino E. Schematic of the proposed mechanism underlying glutamatergic neuronal subtype specification mediated by Tlx3 and CBP. Plos One. DOI: 10.1371/Journal.Pone.0135060.G007  0.318
2015 Shimomura A, Patel D, Wilson SM, Koehler KR, Khanna R, Hashino E. Effects of Tlx3 homeodomain deletion on glutamatergic neuronal marker proteins in ES-derived neurons. Plos One. DOI: 10.1371/Journal.Pone.0135060.G005  0.319
2015 Wang Y, Francois-Moutal L, Moutal A, Cottier K, Melemedjian O, Khanna M, Vanderah T, Khanna R. (399) A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses post-operative pain behaviors The Journal of Pain. 16: S75. DOI: 10.1016/J.Jpain.2015.01.318  0.331
2014 Moutal A, François-Moutal L, Brittain JM, Khanna M, Khanna R. Differential neuroprotective potential of CRMP2 peptide aptamers conjugated to cationic, hydrophobic, and amphipathic cell penetrating peptides. Frontiers in Cellular Neuroscience. 8: 471. PMID 25674050 DOI: 10.3389/Fncel.2014.00471  0.327
2014 Due MR, Yang XF, Allette YM, Randolph AL, Ripsch MS, Wilson SM, Dustrude ET, Khanna R, White FA. Carbamazepine potentiates the effectiveness of morphine in a rodent model of neuropathic pain. Plos One. 9: e107399. PMID 25221944 DOI: 10.1371/Journal.Pone.0107399  0.399
2014 Wilson SM, Moutal A, Melemedjian OK, Wang Y, Ju W, François-Moutal L, Khanna M, Khanna R. The functionalized amino acid (S)-Lacosamide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowth. Frontiers in Cellular Neuroscience. 8: 196. PMID 25104922 DOI: 10.3389/Fncel.2014.00196  0.367
2014 Allette YM, Due MR, Wilson SM, Feldman P, Ripsch MS, Khanna R, White FA. Identification of a functional interaction of HMGB1 with Receptor for Advanced Glycation End-products in a model of neuropathic pain. Brain, Behavior, and Immunity. 42: 169-77. PMID 25014009 DOI: 10.1016/J.Bbi.2014.06.199  0.426
2014 Wilson SM, Ki Yeon S, Yang XF, Park KD, Khanna R. Differential regulation of collapsin response mediator protein 2 (CRMP2) phosphorylation by GSK3ß and CDK5 following traumatic brain injury. Frontiers in Cellular Neuroscience. 8: 135. PMID 24904280 DOI: 10.3389/Fncel.2014.00135  0.336
2014 Brustovetsky T, Pellman JJ, Yang XF, Khanna R, Brustovetsky N. Collapsin response mediator protein 2 (CRMP2) interacts with N-methyl-D-aspartate (NMDA) receptor and Na+/Ca2+ exchanger and regulates their functional activity. The Journal of Biological Chemistry. 289: 7470-82. PMID 24474686 DOI: 10.1074/Jbc.M113.518472  0.356
2013 Lee H, Gold AS, Yang XF, Khanna R, Kohn H. Benzyloxybenzylammonium chlorides: Simple amine salts that display anticonvulsant activity. Bioorganic & Medicinal Chemistry. 21: 7655-62. PMID 24238903 DOI: 10.1016/J.Bmc.2013.10.031  0.32
2013 Quach TT, Wilson SM, Rogemond V, Chounlamountri N, Kolattukudy PE, Martinez S, Khanna M, Belin MF, Khanna R, Honnorat J, Duchemin AM. Mapping CRMP3 domains involved in dendrite morphogenesis and voltage-gated calcium channel regulation. Journal of Cell Science. 126: 4262-73. PMID 23868973 DOI: 10.1242/Jcs.131409  0.405
2013 Dustrude ET, Wilson SM, Ju W, Xiao Y, Khanna R. CRMP2 protein SUMOylation modulates NaV1.7 channel trafficking. The Journal of Biological Chemistry. 288: 24316-31. PMID 23836888 DOI: 10.1074/Jbc.M113.474924  0.387
2013 Feldman P, Khanna R. Challenging the catechism of therapeutics for chronic neuropathic pain: Targeting CaV2.2 interactions with CRMP2 peptides. Neuroscience Letters. 557: 27-36. PMID 23831344 DOI: 10.1016/J.Neulet.2013.06.057  0.431
2013 Zhang YH, Khanna R, Nicol GD. Nerve growth factor/p75 neurotrophin receptor-mediated sensitization of rat sensory neurons depends on membrane cholesterol. Neuroscience. 248: 562-70. PMID 23811397 DOI: 10.1016/J.Neuroscience.2013.06.039  0.305
2013 Lee H, Park KD, Yang XF, Dustrude ET, Wilson SM, Khanna R, Kohn H. (Biphenyl-4-yl)methylammonium chlorides: potent anticonvulsants that modulate Na+ currents. Journal of Medicinal Chemistry. 56: 5931-9. PMID 23772678 DOI: 10.1021/Jm4007092  0.322
2013 Ju W, Li Q, Wilson SM, Brittain JM, Meroueh L, Khanna R. SUMOylation alters CRMP2 regulation of calcium influx in sensory neurons. Channels (Austin, Tex.). 7: 153-9. PMID 23510938 DOI: 10.4161/Chan.24224  0.406
2013 Park KD, Yang XF, Lee H, Dustrude ET, Wang Y, Khanna R, Kohn H. Discovery of lacosamide affinity bait agents that exhibit potent voltage-gated sodium channel blocking properties. Acs Chemical Neuroscience. 4: 463-74. PMID 23509982 DOI: 10.1021/Cn300188H  0.302
2013 Ju W, Li Q, Allette YM, Ripsch MS, White FA, Khanna R. Suppression of pain-related behavior in two distinct rodent models of peripheral neuropathy by a homopolyarginine-conjugated CRMP2 peptide. Journal of Neurochemistry. 124: 869-79. PMID 23106100 DOI: 10.1111/Jnc.12070  0.444
2012 Khanna R, Wilson SM, Brittain JM, Weimer J, Sultana R, Butterfield A, Hensley K. Opening Pandora's jar: a primer on the putative roles of CRMP2 in a panoply of neurodegenerative, sensory and motor neuron, and central disorders. Future Neurology. 7: 749-771. PMID 23308041 DOI: 10.2217/Fnl.12.68  0.35
2012 King AM, Yang XF, Wang Y, Dustrude ET, Barbosa C, Due MR, Piekarz AD, Wilson SM, White FA, Salomé C, Cummins TR, Khanna R, Kohn H. Identification of the benzyloxyphenyl pharmacophore: a structural unit that promotes sodium channel slow inactivation. Acs Chemical Neuroscience. 3: 1037-49. PMID 23259039 DOI: 10.1021/Cn300129D  0.333
2012 Brittain JM, Wang Y, Eruvwetere O, Khanna R. Cdk5-mediated phosphorylation of CRMP-2 enhances its interaction with CaV2.2. Febs Letters. 586: 3813-8. PMID 23022559 DOI: 10.1016/J.Febslet.2012.09.022  0.348
2012 Due MR, Piekarz AD, Wilson N, Feldman P, Ripsch MS, Chavez S, Yin H, Khanna R, White FA. Neuroexcitatory effects of morphine-3-glucuronide are dependent on Toll-like receptor 4 signaling. Journal of Neuroinflammation. 9: 200. PMID 22898544 DOI: 10.1186/1742-2094-9-200  0.379
2012 Wilson SM, Schmutzler BS, Brittain JM, Dustrude ET, Ripsch MS, Pellman JJ, Yeum TS, Hurley JH, Hingtgen CM, White FA, Khanna R. Inhibition of transmitter release and attenuation of anti-retroviral-associated and tibial nerve injury-related painful peripheral neuropathy by novel synthetic Ca2+ channel peptides. The Journal of Biological Chemistry. 287: 35065-77. PMID 22891239 DOI: 10.1074/Jbc.M112.378695  0.372
2012 Piekarz AD, Due MR, Khanna M, Wang B, Ripsch MS, Wang R, Meroueh SO, Vasko MR, White FA, Khanna R. CRMP-2 peptide mediated decrease of high and low voltage-activated calcium channels, attenuation of nociceptor excitability, and anti-nociception in a model of AIDS therapy-induced painful peripheral neuropathy. Molecular Pain. 8: 54. PMID 22828369 DOI: 10.1186/1744-8069-8-54  0.359
2012 Feldman P, Due MR, Ripsch MS, Khanna R, White FA. The persistent release of HMGB1 contributes to tactile hyperalgesia in a rodent model of neuropathic pain. Journal of Neuroinflammation. 9: 180. PMID 22824385 DOI: 10.1186/1742-2094-9-180  0.441
2012 Brittain MK, Brustovetsky T, Brittain JM, Khanna R, Cummins TR, Brustovetsky N. Ifenprodil, a NR2B-selective antagonist of NMDA receptor, inhibits reverse Na+/Ca2+ exchanger in neurons. Neuropharmacology. 63: 974-82. PMID 22820271 DOI: 10.1016/J.Neuropharm.2012.07.012  0.347
2012 Ripsch MS, Ballard CJ, Khanna M, Hurley JH, White FA, Khanna R. A PEPTIDE UNCOUPLING CRMP-2 FROM THE PRESYNAPTIC Ca(2+) CHANNEL COMPLEX DEMONSTRATES EFFICACY IN ANIMAL MODELS OF MIGRAINE AND AIDS THERAPY-INDUCED NEUROPATHY. Translational Neuroscience. 3: 1-8. PMID 22662308 DOI: 10.2478/S13380-012-0002-4  0.405
2012 Brittain JM, Wang Y, Wilson SM, Khanna R. Regulation of CREB signaling through L-type Ca2+ channels by Nipsnap-2. Channels (Austin, Tex.). 6: 94-102. PMID 22627147 DOI: 10.4161/Chan.19415  0.374
2012 Wilson SM, Xiong W, Wang Y, Ping X, Head JD, Brittain JM, Gagare PD, Ramachandran PV, Jin X, Khanna R. Prevention of posttraumatic axon sprouting by blocking collapsin response mediator protein 2-mediated neurite outgrowth and tubulin polymerization. Neuroscience. 210: 451-66. PMID 22433297 DOI: 10.1016/J.Neuroscience.2012.02.038  0.336
2012 Brittain JM, Pan R, You H, Brustovetsky T, Brustovetsky N, Zamponi GW, Lee WH, Khanna R. Disruption of NMDAR-CRMP-2 signaling protects against focal cerebral ischemic damage in the rat middle cerebral artery occlusion model. Channels (Austin, Tex.). 6: 52-9. PMID 22373559 DOI: 10.4161/Chan.18919  0.404
2012 Brittain MK, Brustovetsky T, Sheets PL, Brittain JM, Khanna R, Cummins TR, Brustovetsky N. Delayed calcium dysregulation in neurons requires both the NMDA receptor and the reverse Na+/Ca2+ exchanger. Neurobiology of Disease. 46: 109-17. PMID 22249110 DOI: 10.1016/J.Nbd.2011.12.051  0.345
2011 Wang Y, Khanna R. VOLTAGE-GATED CALCIUM CHANNELS ARE NOT AFFECTED BY THE NOVEL ANTI-EPILEPTIC DRUG LACOSAMIDE. Translational Neuroscience. 2: 13-22. PMID 21949591 DOI: 10.2478/S13380-011-0002-9  0.408
2011 Brittain JM, Chen L, Wilson SM, Brustovetsky T, Gao X, Ashpole NM, Molosh AI, You H, Hudmon A, Shekhar A, White FA, Zamponi GW, Brustovetsky N, Chen J, Khanna R. Neuroprotection against traumatic brain injury by a peptide derived from the collapsin response mediator protein 2 (CRMP2). The Journal of Biological Chemistry. 286: 37778-92. PMID 21832084 DOI: 10.1074/Jbc.M111.255455  0.376
2011 Wilson SM, Brittain JM, Piekarz AD, Ballard CJ, Ripsch MS, Cummins TR, Hurley JH, Khanna M, Hammes NM, Samuels BC, White FA, Khanna R. Further insights into the antinociceptive potential of a peptide disrupting the N-type calcium channel-CRMP-2 signaling complex. Channels (Austin, Tex.). 5: 449-56. PMID 21829088 DOI: 10.4161/Chan.5.5.17363  0.487
2011 Wang Y, Wilson SM, Brittain JM, Ripsch MS, Salomé C, Park KD, White FA, Khanna R, Kohn H. Merging Structural Motifs of Functionalized Amino Acids and α-Aminoamides Results in Novel Anticonvulsant Compounds with Significant Effects on Slow and Fast Inactivation of Voltage-gated Sodium Channels and in the Treatment of Neuropathic Pain. Acs Chemical Neuroscience. 2: 317-322. PMID 21765969 DOI: 10.1021/Cn200024Z  0.412
2011 Brittain JM, Duarte DB, Wilson SM, Zhu W, Ballard C, Johnson PL, Liu N, Xiong W, Ripsch MS, Wang Y, Fehrenbacher JC, Fitz SD, Khanna M, Park CK, Schmutzler BS, ... ... Khanna R, et al. Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca²⁺ channel complex. Nature Medicine. 17: 822-9. PMID 21642979 DOI: 10.1038/Nm.2345  0.476
2011 Wang Y, Park KD, Salome C, Wilson SM, Stables JP, Liu R, Khanna R, Kohn H. Development and characterization of novel derivatives of the antiepileptic drug lacosamide that exhibit far greater enhancement in slow inactivation of voltage-gated sodium channels. Acs Chemical Neuroscience. 2: 90-106. PMID 21532923 DOI: 10.1021/Cn100089B  0.327
2011 Khanna R, Brittain J, Duarte D, Wilson S, Zhu W, Ballard C, Johnson P, Liu N, Xiong W, Ripsch M, Wang Y, Fehrenbacher J, Khanna M, Park C, Brustovetsky N, et al. Suppression of inflammatory and neuropathic pain by uncoupling collapsin response mediator protein 2 (CRMP-2) from the presynaptic calcium channel complex F1000research. 2. DOI: 10.7490/F1000Research.1089589.1  0.419
2010 Wang Y, Brittain JM, Wilson SM, Hingtgen CM, Khanna R. ALTERED CALCIUM CURRENTS AND AXONAL GROWTH IN Nf1 HAPLOINSUFFICIENT MICE. Translational Neuroscience. 1: 106-114. PMID 21949590 DOI: 10.2478/V10134-010-0025-8  0.347
2010 Wang Y, Brittain JM, Wilson SM, Khanna R. Emerging roles of collapsin response mediator proteins (CRMPs) as regulators of voltage-gated calcium channels and synaptic transmission. Communicative & Integrative Biology. 3: 172-5. PMID 20585514 DOI: 10.4161/Cib.3.2.10620  0.386
2010 Wang Y, Brittain JM, Jarecki BW, Park KD, Wilson SM, Wang B, Hale R, Meroueh SO, Cummins TR, Khanna R. In silico docking and electrophysiological characterization of lacosamide binding sites on collapsin response mediator protein-2 identifies a pocket important in modulating sodium channel slow inactivation. The Journal of Biological Chemistry. 285: 25296-307. PMID 20538611 DOI: 10.1074/Jbc.M110.128801  0.41
2009 Chi XX, Schmutzler BS, Brittain JM, Wang Y, Hingtgen CM, Nicol GD, Khanna R. Regulation of N-type voltage-gated calcium channels (Cav2.2) and transmitter release by collapsin response mediator protein-2 (CRMP-2) in sensory neurons. Journal of Cell Science. 122: 4351-62. PMID 19903690 DOI: 10.1242/Jcs.053280  0.436
2009 Brittain JM, Piekarz AD, Wang Y, Kondo T, Cummins TR, Khanna R. An atypical role for collapsin response mediator protein 2 (CRMP-2) in neurotransmitter release via interaction with presynaptic voltage-gated calcium channels. The Journal of Biological Chemistry. 284: 31375-90. PMID 19755421 DOI: 10.1074/Jbc.M109.009951  0.421
2007 Chan AW, Khanna R, Li Q, Stanley EF. Munc18: a presynaptic transmitter release site N type (CaV2.2) calcium channel interacting protein. Channels (Austin, Tex.). 1: 11-20. PMID 19170253 DOI: 10.4161/Chan.3694  0.377
2007 Khanna R, Li Q, Schlichter LC, Stanley EF. The transmitter release-site CaV2.2 channel cluster is linked to an endocytosis coat protein complex. The European Journal of Neuroscience. 26: 560-74. PMID 17686037 DOI: 10.1111/J.1460-9568.2007.05681.X  0.31
2007 Khanna R, Li Q, Bewersdorf J, Stanley EF. The presynaptic CaV2.2 channel-transmitter release site core complex. The European Journal of Neuroscience. 26: 547-59. PMID 17686036 DOI: 10.1111/J.1460-9568.2007.05680.X  0.338
2007 Khanna R, Zougman A, Stanley EF. A proteomic screen for presynaptic terminal N-type calcium channel (CaV2.2) binding partners. Journal of Biochemistry and Molecular Biology. 40: 302-14. PMID 17562281 DOI: 10.5483/Bmbrep.2007.40.3.302  0.376
2006 Khanna R, Li Q, Sun L, Collins TJ, Stanley EF. N type Ca2+ channels and RIM scaffold protein covary at the presynaptic transmitter release face but are components of independent protein complexes. Neuroscience. 140: 1201-8. PMID 16757118 DOI: 10.1016/J.Neuroscience.2006.04.053  0.34
2006 Sun L, Li Q, Khanna R, Chan AW, Wong F, Stanley EF. Transmitter release face Ca2+ channel clusters persist at isolated presynaptic terminals. The European Journal of Neuroscience. 23: 1391-6. PMID 16553800 DOI: 10.1111/J.1460-9568.2006.04653.X  0.318
2006 Khanna R, Sun L, Li Q, Guo L, Stanley EF. Long splice variant N type calcium channels are clustered at presynaptic transmitter release sites without modular adaptor proteins. Neuroscience. 138: 1115-25. PMID 16473471 DOI: 10.1016/J.Neuroscience.2005.12.050  0.31
2005 Wan J, Khanna R, Sandusky M, Papazian DM, Jen JC, Baloh RW. CACNA1A mutations causing episodic and progressive ataxia alter channel trafficking and kinetics. Neurology. 64: 2090-7. PMID 15985579 DOI: 10.1212/01.Wnl.0000167409.59089.C0  0.359
2004 Khanna R, Lee EJ, Papazian DM. Transient calnexin interaction confers long-term stability on folded K+ channel protein in the ER. Journal of Cell Science. 117: 2897-908. PMID 15161937 DOI: 10.1242/Jcs.01141  0.323
2003 Koni PA, Khanna R, Chang MC, Tang MD, Kaczmarek LK, Schlichter LC, Flavella RA. Compensatory anion currents in Kv1.3 channel-deficient thymocytes. The Journal of Biological Chemistry. 278: 39443-51. PMID 12878608 DOI: 10.1074/Jbc.M304879200  0.342
2001 Joiner WJ, Khanna R, Schlichter LC, Kaczmarek LK. Calmodulin regulates assembly and trafficking of SK4/IK1 Ca2+-activated K+ channels. The Journal of Biological Chemistry. 276: 37980-5. PMID 11495911 DOI: 10.1074/Jbc.M104965200  0.361
2001 Khanna R, Myers MP, Lainé M, Papazian DM. Glycosylation increases potassium channel stability and surface expression in mammalian cells. The Journal of Biological Chemistry. 276: 34028-34. PMID 11427541 DOI: 10.1074/Jbc.M105248200  0.305
2001 Chang MC, Khanna R, Schlichter LC. Regulation of Kv1.3 channels in activated human T lymphocytes by Ca(2+)-dependent pathways. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 11: 123-34. PMID 11410708 DOI: 10.1159/000047800  0.349
2001 Khanna R, Roy L, Zhu X, Schlichter LC. K+ channels and the microglial respiratory burst. American Journal of Physiology. Cell Physiology. 280: C796-806. PMID 11245596 DOI: 10.1152/Ajpcell.2001.280.4.C796  0.367
2000 Cayabyab FS, Khanna R, Jones OT, Schlichter LC. Suppression of the rat microglia Kv1.3 current by src-family tyrosine kinases and oxygen/glucose deprivation. The European Journal of Neuroscience. 12: 1949-60. PMID 10886336 DOI: 10.1046/J.1460-9568.2000.00083.X  0.339
2000 Jugloff DG, Khanna R, Schlichter LC, Jones OT. Internalization of the Kv1.4 potassium channel is suppressed by clustering interactions with PSD-95. The Journal of Biological Chemistry. 275: 1357-64. PMID 10625685 DOI: 10.1074/Jbc.275.2.1357  0.345
1999 Khanna R, Chang MC, Joiner WJ, Kaczmarek LK, Schlichter LC. hSK4/hIK1, a calmodulin-binding KCa channel in human T lymphocytes. Roles in proliferation and volume regulation. The Journal of Biological Chemistry. 274: 14838-49. PMID 10329683 DOI: 10.1074/Jbc.274.21.14838  0.354
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