Mark E. Obrenovich, PhD - Publications

Affiliations: 
Pathology Case Western Reserve University, Cleveland Heights, OH, United States 
Website:
http://www.biomedexperts.com/Profile.bme/1036677/Mark_E_Obrenovich

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Obrenovich ME, Shola D, Schroedel K, Agrahari A, Lonsdale D. The role of trace elements, thiamin (e) and transketolase in autism and autistic spectrum disorder. Frontiers in Bioscience (Elite Edition). 7: 229-41. PMID 25553376  1
2015 Obrenovich ME, Shola D, Schroedel K, Agrahari A, Lonsdale D. The role of trace elements, thiamin(e) in autism and autistic spectrum disorder Frontiers in Bioscience - Elite. 7: 263-277. DOI: 10.2741/E730  1
2013 Aliev G, Obrenovich ME, Tabrez S, Jabir NR, Reddy VP, Li Y, Burnstock G, Cacabelos R, Kamal MA. Link between cancer and Alzheimer disease via oxidative stress induced by nitric oxide-dependent mitochondrial DNA overproliferation and deletion. Oxidative Medicine and Cellular Longevity. 2013: 962984. PMID 23691268 DOI: 10.1155/2013/962984  1
2012 Aliev G, Li Y, Palacios HH, Obrenovich ME, Bragin V, Bragin I, Shevtsova E, Klochkov SG, Kosenko EA, Cacabelos R, Kaminsky YG, Bachurin SO, Benberin VV. Oxidative stress-induced mitochondrial damage as a hallmark for drug development in the context of the neurodegeneration, cardiovascular, and cerebrovascular diseases Systems Biology of Free Radicals and Antioxidants. 2083-2126. DOI: 10.1007/978-3-642-30018-9_208  1
2012 Aliev G, Li Y, Palacios HH, Obrenovich ME, Bragin V, Bragin I, Shevtsova E, Klochkov SG, Kosenko EA, Kaminsky YG, Bachurin SO, Cacabelos R. Atherosclerotic lesions and mitochondrial dna deletions as a primary hallmark of the brain microcirculation - Implication in the pathogenesis of Alzheimer's disease Systems Biology of Free Radicals and Antioxidants. 2127-2145. DOI: 10.1007/978-3-642-30018-9_203  1
2011 Aliev G, Li Y, Palacios HH, Obrenovich ME. Oxidative stress induced mitochondrial DNA deletion as a hallmark for the drug development in the context of the cerebrovascular diseases. Recent Patents On Cardiovascular Drug Discovery. 6: 222-41. PMID 21906026  1
2011 Obrenovich ME, Shamberger RJ, Lonsdale D. Altered heavy metals and transketolase found in autistic spectrum disorder. Biological Trace Element Research. 144: 475-86. PMID 21755304 DOI: 10.1007/s12011-011-9146-2  1
2011 Horecký J, Gvozdjáková A, Kucharská J, Obrenovich ME, Palacios HH, Li Y, Vančová O, Aliev G. Effects of coenzyme Q and creatine supplementation on brain energy metabolism in rats exposed to chronic cerebral hypoperfusion. Current Alzheimer Research. 8: 868-75. PMID 21592049 DOI: 10.2174/156720511798192727  1
2011 Obrenovich ME, Li Y, Parvathaneni K, Yendluri BB, Palacios HH, Leszek J, Aliev G. Antioxidants in health, disease and aging. Cns & Neurological Disorders Drug Targets. 10: 192-207. PMID 21226664  1
2011 Sieradzki A, Yendluri BB, Palacios HH, Parvathaneni K, Reddy VP, Obrenovich ME, GÄ…siorowski K, Leszek J, Aliev G. Implication of oncogenic signaling pathways as a treatment strategy for neurodegenerative disorders - contemporary approaches. Cns & Neurological Disorders Drug Targets. 10: 175-83. PMID 21222633  1
2011 Palacios HH, Yendluri BB, Parvathaneni K, Shadlinski VB, Obrenovich ME, Leszek J, Gokhman D, GÄ…siorowski K, Bragin V, Aliev G. Mitochondrion-specific antioxidants as drug treatments for Alzheimer disease. Cns & Neurological Disorders Drug Targets. 10: 149-62. PMID 21222631  1
2011 Aliev G, Palacios HH, Betts B, Obrenovich ME, Gasiorowski K, Gokhman D, Leszek J, Bragin V, Herrera AS. Mitochondrion selective antioxidants as drug treatments for Alzheimer disease Vascular Dementia: Risk Factors, Diagnosis and Treatment. 105-128.  1
2011 Aliev G, Palacios HH, Herrera AS, Obrenovich ME. GRK2 Overexpression is a primary hallmark of vascular hypoperfusion and mitochondrial lesions during early Alzheimer disease: New target for drug treatment? Vascular Dementia: Risk Factors, Diagnosis and Treatment. 79-103.  1
2011 Aliev G, Palacios HH, Obrenovich ME, Gokhman D, Gasiorowski K, Bragin V, Herrera AS. Oxidative stress induced vascular hypoperfusion, mitochondrial failure are missing links for the development of Alzheimer disease Vascular Dementia: Risk Factors, Diagnosis and Treatment. 49-78.  1
2011 Obrenovich ME, Gasiorowski K, Palacios HH, Gokhman D, Shadlinski VB, Bragin V, Leszek J, Aliev G. Selective loss of GRK2 regulation and its consequences: Cerebrovascular complications and alzheimer disease | Wybiórczy ubytek w zakresie regulacji GRK2 i jego konsekwencje: Powikłania naczyniowo-mózgowe i choroba alzheimera Psychogeriatria Polska. 8: 81-98.  1
2010 Aliev G, Palacios HH, Gasimov E, Obrenovich ME, Morales L, Leszek J, Bragin V, Solís Herrera A, Gokhman D. Oxidative Stress Induced Mitochondrial Failure and Vascular Hypoperfusion as a Key Initiator for the Development of Alzheimer Disease. Pharmaceuticals (Basel, Switzerland). 3: 158-187. PMID 27713247 DOI: 10.3390/ph3010158  1
2010 Obrenovich ME, Nair NG, Beyaz A, Aliev G, Reddy VP. The role of polyphenolic antioxidants in health, disease, and aging. Rejuvenation Research. 13: 631-43. PMID 20818981 DOI: 10.1089/rej.2010.1043  1
2010 Dagdanova A, Ilchenko S, Notari S, Yang Q, Obrenovich ME, Hatcher K, McAnulty P, Huang L, Zou W, Kong Q, Gambetti P, Chen SG. Characterization of the prion protein in human urine. The Journal of Biological Chemistry. 285: 30489-95. PMID 20670940 DOI: 10.1074/jbc.M110.161794  1
2010 Aliev G, Palacios HH, Gasimov E, Obrenovich ME, Morales L, Leszek J, Bragin V, Herrera AS, Gokhman D. Oxidative stress induced mitochondrial failure and vascular hypoperfusion as a key initiator for the development of alzheimer disease Pharmaceuticals. 3: 158-187. DOI: 10.3390/ph3010158  1
2009 Obrenovich ME, Palacios HH, Gasimov E, Leszek J, Aliev G. The GRK2 Overexpression Is a Primary Hallmark of Mitochondrial Lesions during Early Alzheimer Disease. Cardiovascular Psychiatry and Neurology. 2009: 327360. PMID 20204079 DOI: 10.1155/2009/327360  1
2009 Aliev G, Palacios HH, Walrafen B, Lipsitt AE, Obrenovich ME, Morales L. Brain mitochondria as a primary target in the development of treatment strategies for Alzheimer disease. The International Journal of Biochemistry & Cell Biology. 41: 1989-2004. PMID 19703659 DOI: 10.1016/j.biocel.2009.03.015  1
2009 Aliev G, Palacios HH, Lipsitt AE, Fischbach K, Lamb BT, Obrenovich ME, Morales L, Gasimov E, Bragin V. Nitric oxide as an initiator of brain lesions during the development of Alzheimer disease. Neurotoxicity Research. 16: 293-305. PMID 19526276 DOI: 10.1007/s12640-009-9066-5  1
2009 Shenk JC, Liu J, Fischbach K, Xu K, Puchowicz M, Obrenovich ME, Gasimov E, Alvarez LM, Ames BN, Lamanna JC, Aliev G. The effect of acetyl-L-carnitine and R-alpha-lipoic acid treatment in ApoE4 mouse as a model of human Alzheimer's disease. Journal of the Neurological Sciences. 283: 199-206. PMID 19342064 DOI: 10.1016/j.jns.2009.03.002  1
2009 Obrenovich ME, Morales LA, Cobb CJ, Shenk JC, Méndez GM, Fischbach K, Smith MA, Qasimov EK, Perry G, Aliev G. Insights into cerebrovascular complications and Alzheimer disease through the selective loss of GRK2 regulation. Journal of Cellular and Molecular Medicine. 13: 853-65. PMID 19292735 DOI: 10.1111/j.1582-4934.2008.00512.x  1
2009 Aliev G, Liu J, Shenk JC, Fischbach K, Pacheco GJ, Chen SG, Obrenovich ME, Ward WF, Richardson AG, Smith MA, Gasimov E, Perry G, Ames BN. Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats. Journal of Cellular and Molecular Medicine. 13: 320-33. PMID 18373733 DOI: 10.1111/j.1582-4934.2008.00324.x  1
2009 Aliev G, Palacios HH, Pacheco GJ, Gasimov E, Morales L, Gokhman D, Obrenovich ME, Bragin V, Soils A, Leszek J. Oxidative stress induced mitochondrial failure and cellular hypoperfusion: Implication in the pathogenesis of Alzheimer disease Psychogeriatria Polska. 6: 155-179.  1
2008 Aliev G, Obrenovich ME, Reddy VP, Shenk JC, Moreira PI, Nunomura A, Zhu X, Smith MA, Perry G. Antioxidant therapy in Alzheimer's disease: theory and practice. Mini Reviews in Medicinal Chemistry. 8: 1395-406. PMID 18991755 DOI: 10.2174/138955708786369582  1
2008 Aliev G, Gasimov E, Obrenovich ME, Fischbach K, Shenk JC, Smith MA, Perry G. Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels: implication in the pathogenesis of Alzheimer's disease. Vascular Health and Risk Management. 4: 721-30. PMID 18827923  1
2006 Aliev G, Miller JP, Leifer DW, Obrenovich ME, Shenk JC, Smith MA, Lamanna JC, Perry G, Lust DW, Cohen AR. Ultrastructural analysis of a murine model of congenital hydrocephalus produced by overexpression of transforming growth factor-beta1 in the central nervous system. Journal of Submicroscopic Cytology and Pathology. 38: 85-91. PMID 17784635  1
2006 Fan X, Reneker LW, Obrenovich ME, Strauch C, Cheng R, Jarvis SM, Ortwerth BJ, Monnier VM. Vitamin C mediates chemical aging of lens crystallins by the Maillard reaction in a humanized mouse model. Proceedings of the National Academy of Sciences of the United States of America. 103: 16912-7. PMID 17075057 DOI: 10.1073/pnas.0605101103  1
2006 Obrenovich ME, Smith MA, Siedlak SL, Chen SG, de la Torre JC, Perry G, Aliev G. Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions. Neurotoxicity Research. 10: 43-56. PMID 17000469 DOI: 10.1007/BF03033333  1
2006 Obrenovich ME, Fan X, Satake M, Jarvis SM, Reneker L, Reddan JR, Monnier VM. Relative suppression of the sodium-dependent Vitamin C transport in mouse versus human lens epithelial cells. Molecular and Cellular Biochemistry. 293: 53-62. PMID 16933033 DOI: 10.1007/s11010-006-2678-7  1
2006 Webber KM, Casadesus G, Zhu X, Obrenovich ME, Atwood CS, Perry G, Bowen RL, Smith MA. The cell cycle and hormonal fluxes in Alzheimer disease: a novel therapeutic target. Current Pharmaceutical Design. 12: 691-7. PMID 16472159 DOI: 10.2174/138161206775474305  1
2006 Raina AK, Garrett MR, Previll LA, Obrenovich ME, Hartzler AW, Webber KM, Casadesus G, Lee HG, Perry G, Zhu X, Smith MA. Oncogenic parallels in Alzheimer disease International Journal of Neuroprotection and Neuroregeneration. 2: 80-85.  1
2005 Obrenovich ME, Monnier VM. Apoptotic killing of fibroblasts by matrix-bound advanced glycation endproducts. Science of Aging Knowledge Environment : Sage Ke. 2005: pe3. PMID 15673817 DOI: 10.1126/sageke.2005.4.pe3  1
2005 Aliev G, Obrenovich ME, Seyidova D, de la Torre JC. Exploring ischemia-induced vascular lesions and potential pharmacological intervention strategies. Histology and Histopathology. 20: 261-73. PMID 15578444  1
2004 Aliyev A, Seyidova D, Rzayev N, Obrenovich ME, Lamb BT, Chen SG, Smith MA, Perry G, de la Torre JC, Aliev G. Is nitric oxide a key target in the pathogenesis of brain lesions during the development of Alzheimer's disease? Neurological Research. 26: 547-53. PMID 15265272 DOI: 10.1179/01610425017613  1
2004 Obrenovich ME, Monnier VM. Glycation stimulates amyloid formation. Science of Aging Knowledge Environment : Sage Ke. 2004: pe3. PMID 14724325 DOI: 10.1126/sageke.2004.2.pe3  1
2003 Aliev G, Smith MA, Obrenovich ME, de la Torre JC, Perry G. Role of vascular hypoperfusion-induced oxidative stress and mitochondria failure in the pathogenesis of Azheimer disease. Neurotoxicity Research. 5: 491-504. PMID 14715433 DOI: 10.1007/BF03033159  1
2003 Aliev G, Obrenovich ME, Seyidova D, Rzayev NM, Aliyev AS, Raina AK, Lamanna JC, Smith MA, Perry G. X-ray contrast media induce aortic endothelial damage, which can be prevented with prior heparin treatment. Journal of Submicroscopic Cytology and Pathology. 35: 253-66. PMID 14690173  1
2003 Aliev G, Seyidova D, Lamb BT, Obrenovich ME, Siedlak SL, Vinters HV, Friedland RP, LaManna JC, Smith MA, Perry G. Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice. Neurological Research. 25: 665-74. PMID 14503022 DOI: 10.1179/016164103101201977  1
2003 Atwood CS, Obrenovich ME, Liu T, Chan H, Perry G, Smith MA, Martins RN. Amyloid-beta: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-beta. Brain Research. Brain Research Reviews. 43: 1-16. PMID 14499458 DOI: 10.1016/S0165-0173(03)00174-7  1
2003 Aliev G, Obrenovich ME, Smith MA, Perry G. Hypoperfusion, Mitochondria Failure, Oxidative Stress, and Alzheimer Disease. Journal of Biomedicine & Biotechnology. 2003: 162-163. PMID 12975531 DOI: 10.1155/S1110724303305029  1
2003 Obrenovich ME, Monnier VM. Vitamin B1 blocks damage caused by hyperglycemia. Science of Aging Knowledge Environment : Sage Ke. 2003: PE6. PMID 12844520  1
2003 Sell DR, Lane MA, Obrenovich ME, Mattison JA, Handy A, Ingram DK, Cutler RG, Roth GS, Monnier VM. The effect of caloric restriction on glycation and glycoxidation in skin collagen of nonhuman primates. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 58: 508-16. PMID 12807921  1
2003 Ogawa O, Zhu X, Lee HG, Raina A, Obrenovich ME, Bowser R, Ghanbari HA, Castellani RJ, Perry G, Smith MA. Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe? Acta Neuropathologica. 105: 524-8. PMID 12677454 DOI: 10.1007/s00401-003-0684-3  1
2002 Monnier VM, Obrenovich ME. Wake up and smell the maillard reaction. Science of Aging Knowledge Environment : Sage Ke. 2002: pe21. PMID 14603025 DOI: 10.1126/sageke.2002.50.pe21  0.32
2002 Reddy VP, Obrenovich ME, Atwood CS, Perry G, Smith MA. Involvement of Maillard reactions in Alzheimer disease. Neurotoxicity Research. 4: 191-209. PMID 12829400 DOI: 10.1080/1029840290007321  1
2002 Obrenovich ME, Joseph JA, Atwood CS, Perry G, Smith MA. Amyloid-beta: a (life) preserver for the brain. Neurobiology of Aging. 23: 1097-9. PMID 12470809  1
2002 Castellani R, Hirai K, Aliev G, Drew KL, Nunomura A, Takeda A, Cash AD, Obrenovich ME, Perry G, Smith MA. Role of mitochondrial dysfunction in Alzheimer's disease. Journal of Neuroscience Research. 70: 357-60. PMID 12391597 DOI: 10.1002/jnr.10389  1
Show low-probability matches.