Year |
Citation |
Score |
2024 |
López-Canul M, He Q, Sasson T, Ettaoussi M, De Gregorio D, Ochoa-Sanchez R, Catoire H, Posa L, Rouleau G, Beaulieu JM, Comai S, Gobbi G. Selective Enhancement of REM Sleep in Male Rats through Activation of MT Receptors Located in the Locus Coeruleus Norepinephrine neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 38744530 DOI: 10.1523/JNEUROSCI.0914-23.2024 |
0.73 |
|
2023 |
Tassan Mazzocco M, Pisanu C, Russo L, Acconcia C, Cambiaghi M, De Girolamo S, Squassina A, Cherchi L, Monzani E, Scebba F, Angeloni D, De Gregorio D, Nasini S, Dall'Acqua S, Sut S, ... ... Gobbi G, et al. Melatonin MT receptors as a target for the psychopharmacology of bipolar disorder: A translational study. Pharmacological Research. 198: 106993. PMID 37972722 DOI: 10.1016/j.phrs.2023.106993 |
0.303 |
|
2023 |
Pearl-Dowler L, Posa L, Lopez-Canul M, Teggin A, Gobbi G. Anti-allodynic and medullary modulatory effects of a single dose of delta-9-tetrahydrocannabinol (THC) in neuropathic rats tolerant to morphine. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110805. PMID 37257771 DOI: 10.1016/j.pnpbp.2023.110805 |
0.689 |
|
2023 |
Medeiros AC, Medeiros P, Ruggiero RN, De Gregorio D, Gobbi G, Silva Júnior PI, Dos Santos WF, Coimbra NC, de Freitas RL. Acanthoscurria gomesiana spider-derived Mygalin in the prelimbic prefrontal cortex modulates neuropathic pain and depression comorbid. Journal of Biochemical and Molecular Toxicology. e23353. PMID 37069807 DOI: 10.1002/jbt.23353 |
0.3 |
|
2022 |
Posa L, De Gregorio D, He Q, Lopez-Canul M, Darcq E, Rullo L, Pearl-Dowler L, Luongo L, Candeletti S, Romualdi P, Kieffer BL, Gobbi G. Supraspinal melatonin MT receptor agonism alleviates pain via a neural circuit that recruits mu opioid receptors. Journal of Pineal Research. PMID 35996205 DOI: 10.1111/jpi.12825 |
0.804 |
|
2022 |
De Gregorio D, Inserra A, Enns JP, Markopoulos A, Pileggi M, El Rahimy Y, Lopez-Canul M, Comai S, Gobbi G. Repeated lysergic acid diethylamide (LSD) reverses stress-induced anxiety-like behavior, cortical synaptogenesis deficits and serotonergic neurotransmission decline. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 47: 1188-1198. PMID 35301424 DOI: 10.1038/s41386-022-01301-9 |
0.37 |
|
2021 |
De Gregorio D, Popic J, Enns JP, Inserra A, Skalecka A, Markopoulos A, Posa L, Lopez-Canul M, Qianzi H, Lafferty CK, Britt JP, Comai S, Aguilar-Valles A, Sonenberg N, Gobbi G. Lysergic acid diethylamide (LSD) promotes social behavior through mTORC1 in the excitatory neurotransmission. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33495318 DOI: 10.1073/pnas.2020705118 |
0.754 |
|
2020 |
De Gregorio D, Dean Conway J, Canul ML, Posa L, Bambico FR, Gobbi G. Effects of chronic exposure to low doses of Δ9- tetrahydrocannabinol in adolescence and adulthood on serotonin/norepinephrine neurotransmission and emotional behaviors. The International Journal of Neuropsychopharmacology. PMID 32725198 DOI: 10.1093/Ijnp/Pyaa058 |
0.771 |
|
2020 |
Posa L, Lopez-Canul M, Rullo L, De Gregorio D, Dominguez-Lopez S, Aboud MK, Felicia Caputi F, Candeletti S, Romualdi P, Gobbi G. Nociceptive responses in MT receptor knockout mice compared to MT and double MT /MT receptor knockout mice. Journal of Pineal Research. e12671. PMID 32430930 DOI: 10.1111/Jpi.12671 |
0.783 |
|
2020 |
Comai S, De Gregorio D, Posa L, Ochoa-Sanchez R, Bedini A, Gobbi G. Dysfunction of serotonergic activity and emotional responses across the light-dark cycle in mice lacking MT receptors. Journal of Pineal Research. e12653. PMID 32239546 DOI: 10.1111/Jpi.12653 |
0.77 |
|
2019 |
Bambico FR, Li Z, Creed M, De Gregorio D, Diwan M, Li J, McNeill S, Gobbi G, Raymond R, Nobrega JN. A Key Role for Prefrontocortical Small Conductance Calcium-Activated Potassium Channels in Stress Adaptation and Rapid Antidepressant Response. Cerebral Cortex (New York, N.Y. : 1991). PMID 31504265 DOI: 10.1093/Cercor/Bhz187 |
0.771 |
|
2019 |
López-Canul M, Min SH, Posa L, De Gregorio D, Bedini A, Spadoni G, Gobbi G, Comai S. Melatonin MT and MT Receptors Exhibit Distinct Effects in the Modulation of Body Temperature across the Light/Dark Cycle. International Journal of Molecular Sciences. 20. PMID 31108968 DOI: 10.3390/Ijms20102452 |
0.739 |
|
2019 |
Comai S, Lopez-Canul M, De Gregorio D, Posner A, Ettaoussi M, Guarnieri F, Gobbi G. Melatonin MT receptor as a novel target in neuropsychopharmacology: MT ligands, pathophysiological and therapeutic implications and perspectives. Pharmacological Research. PMID 31029764 DOI: 10.1016/J.Phrs.2019.04.015 |
0.455 |
|
2019 |
Gobbi G, Comai S. Differential Function of Melatonin MT and MT Receptors in REM and NREM Sleep. Frontiers in Endocrinology. 10: 87. PMID 30881340 DOI: 10.3389/Fendo.2019.00087 |
0.389 |
|
2019 |
Lopez-Canul M, Sasson T, Ochoa-Sanchez R, He Q, Yin S, De Gregorio D, Posa L, Comai S, Gobbi G. Effect of the selective melatonin MT1 receptor partial agonist UCM871 in the activity of noraphineprine neurons of the locus coeruleus during the sleep/wake cycle Sleep Medicine. 64: S231. DOI: 10.1016/J.Sleep.2019.11.646 |
0.746 |
|
2019 |
De Gregorio D, Popic J, Enns J, Posa L, Aguilar-Valles A, Sonenberg N, Gobbi G. S.17.02 Lysergic acid diethylamide reverses anxious-like behaviour and modulates serotonergic neurotransmission in a chronic stress model European Neuropsychopharmacology. 29: S12-S13. DOI: 10.1016/j.euroneuro.2019.09.042 |
0.686 |
|
2018 |
Gobbi G, Comai S. Sleep well. Untangling the role of melatonin MT1 and MT2 receptor in sleep. Journal of Pineal Research. e12544. PMID 30586215 DOI: 10.1111/Jpi.12544 |
0.394 |
|
2018 |
De Gregorio D, Enns JP, Nuñez NA, Posa L, Gobbi G. d-Lysergic acid diethylamide, psilocybin, and other classic hallucinogens: Mechanism of action and potential therapeutic applications in mood disorders. Progress in Brain Research. 242: 69-96. PMID 30471683 DOI: 10.1016/Bs.Pbr.2018.07.008 |
0.767 |
|
2018 |
De Gregorio D, Manchia M, Carpiniello B, Valtorta F, Nobile M, Gobbi G, Comai S. Role of palmitoylethanolamide (PEA) in depression: Translational evidence. Journal of Affective Disorders. PMID 30391203 DOI: 10.1016/J.Jad.2018.10.117 |
0.319 |
|
2018 |
De Gregorio D, McLaughlin RJ, Posa L, Ochoa-Sanchez R, Enns J, Lopez-Canul M, Aboud M, Maione S, Comai S, Gobbi G. Cannabidiol modulates serotonergic transmission and prevents allodynia and anxiety-like behavior in a model of neuropathic pain. Pain. PMID 30157131 DOI: 10.1097/J.Pain.0000000000001386 |
0.815 |
|
2018 |
Aguilar-Valles A, Haji N, De Gregorio D, Matta-Camacho E, Eslamizade MJ, Popic J, Sharma V, Cao R, Rummel C, Tanti A, Wiebe S, Nuñez N, Comai S, Nadon R, Luheshi G, ... ... Gobbi G, et al. Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E. Nature Communications. 9: 2459. PMID 29941989 DOI: 10.1038/S41467-018-04883-5 |
0.363 |
|
2018 |
Bambico FR, Comai S, Hasan MSN, Conway JD, Darvish-Gane S, Hamani C, Gobbi G, Nobrega JN. High frequency stimulation of the anterior vermis modulates behavioural response to chronic stress: Involvement of the prefrontal cortex and dorsal raphe? Neurobiology of Disease. PMID 29727711 DOI: 10.1016/J.Nbd.2018.03.011 |
0.75 |
|
2018 |
Messaoud A, Rym M, Douki W, Neffati F, Najjar MF, Gobbi G, Valtorta F, Gaha L, Comai S. Reduced peripheral availability of tryptophan and increased activation of the kynurenine pathway and cortisol correlate with major depression and suicide. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-28. PMID 29683396 DOI: 10.1080/15622975.2018.1468031 |
0.361 |
|
2018 |
Atkin T, Comai S, Gobbi G. Drugs for Insomnia beyond Benzodiazepines: Pharmacology, Clinical Applications, and Discovery. Pharmacological Reviews. 70: 197-245. PMID 29487083 DOI: 10.1124/Pr.117.014381 |
0.329 |
|
2017 |
Posa L, De Gregorio D, Gobbi G, Comai S. Targeting melatonin MT2 receptors: A novel pharmacological avenue for inflammatory and neuropathic pain. Current Medicinal Chemistry. PMID 28183259 DOI: 10.2174/0929867324666170209104926 |
0.75 |
|
2017 |
Gobbi G, Lopez-Canul M, Ochoa-Sanchez R, Comai S. Anxiolytic, hypnotic and analgesic properties of melatonin MT2 receptor partial agonists European Neuropsychopharmacology. 27: S569-S570. DOI: 10.1016/S0924-977X(17)31099-4 |
0.411 |
|
2017 |
Comai S, Posa L, Ochoa-Sanchez R, Spadoni G, Gobbi G. Neuropsychopharmacological properties of novel melatonin MT1 receptor ligands European Neuropsychopharmacology. 27: S569. DOI: 10.1016/S0924-977X(17)31098-2 |
0.721 |
|
2017 |
De Gregorio D, Posa L, Ochoa-Sanchez R, McLaughlin R, Maione S, Comai S, Gobbi G. D-lysergic diethylamide modulates dopaminergic neurons of ventral tegmental area via 5-HT1A, D2 and TAAR1 receptors European Neuropsychopharmacology. 27: S53-S54. DOI: 10.1016/S0924-977X(17)30124-4 |
0.786 |
|
2016 |
De Gregorio D, Comai S, Posa L, Gobbi G. d-Lysergic Acid Diethylamide (LSD) as a Model of Psychosis: Mechanism of Action and Pharmacology. International Journal of Molecular Sciences. 17. PMID 27886063 DOI: 10.3390/Ijms17111953 |
0.756 |
|
2016 |
De Gregorio D, Posa L, Ochoa-Sanchez R, McLaughlin R, Maione S, Comai S, Gobbi G. The hallucinogen d-lysergic diethylamide (LSD) decreases dopamine firing activity through 5-HT1A, D2 and TAAR1 receptors. Pharmacological Research. 113: 81-91. PMID 27544651 DOI: 10.1016/J.Phrs.2016.08.022 |
0.823 |
|
2016 |
Comai S, Bertazzo A, Vachon J, Daigle M, Toupin J, Côté G, Turecki G, Gobbi G. Tryptophan via serotonin/kynurenine pathways abnormalities in a large cohort of aggressive inmates: Markers for aggression. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 27117820 DOI: 10.1016/J.Pnpbp.2016.04.012 |
0.368 |
|
2016 |
Gobbi G, Lopez-Canul M, Palazzo E, Dominguez-Lopez S, Luongo L, Lacoste B, Comai S, Angeloni D, Fraschini F, Spadoni G, Bedini A, Tarzia G, Maione S, Granados-Soto V. PT628. First in class melatonin MT2 receptors agonists for neuropathic pain The International Journal of Neuropsychopharmacology. 19: 30-30. DOI: 10.1093/Ijnp/Pyw044.628 |
0.342 |
|
2016 |
Gregorio DD, Posa L, Ochoa-Sanchez R, McLaughlin R, Maione S, Comai S, Gobbi G. PM361. The hallucinogen D-lysergic diethylamide (LSD) decreases dopamine firing activity through 5-HT1A, D2 and TAAR1 receptors The International Journal of Neuropsychopharmacology. 19: 32-32. DOI: 10.1093/Ijnp/Pyw041.361 |
0.777 |
|
2016 |
Morales-Medina JC, Juarez I, Dominguez-Lopez S, Kandimalla R, Gobbi G, Flores G, Quirion R. The Y2 receptor antagonist BIIE0246 reverses corticosterone-induced anxiogenic-related behavior and neuronal hypertrophy Neuropeptides. 55: 21. DOI: 10.1016/J.Npep.2015.11.058 |
0.431 |
|
2015 |
Bambico FR, Duranti A, Nobrega JN, Gobbi G. The fatty acid amide hydrolase inhibitor URB597 modulates serotonin-dependent emotional behaviour, and serotonin1A and serotonin2A/C activity in the hippocampus. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26747370 DOI: 10.1016/J.Euroneuro.2015.12.027 |
0.763 |
|
2015 |
López-Canul M, Comai S, Domínguez-López S, Granados-Soto V, Gobbi G. Antinociceptive properties of selective MT2 melatonin receptor partial agonists. European Journal of Pharmacology. 764: 424-32. PMID 26162699 DOI: 10.1016/J.Ejphar.2015.07.010 |
0.405 |
|
2015 |
Lacoste B, Angeloni D, Dominguez-Lopez S, Calderoni S, Mauro A, Fraschini F, Descarries L, Gobbi G. Anatomical and cellular localization of melatonin MT1 and MT2 receptors in the adult rat brain. Journal of Pineal Research. 58: 397-417. PMID 25726952 DOI: 10.1111/Jpi.12224 |
0.4 |
|
2015 |
Comai S, Ochoa-Sanchez R, Dominguez-Lopez S, Bambico FR, Gobbi G. Melancholic-Like behaviors and circadian neurobiological abnormalities in melatonin MT1 receptor knockout mice. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25638817 DOI: 10.1093/Ijnp/Pyu075 |
0.757 |
|
2015 |
Lopez-Canul M, Palazzo E, Dominguez-Lopez S, Luongo L, Lacoste B, Comai S, Angeloni D, Fraschini F, Boccella S, Spadoni G, Bedini A, Tarzia G, Maione S, Granados-Soto V, Gobbi G. Selective melatonin MT2 receptor ligands relieve neuropathic pain through modulation of brainstem descending antinociceptive pathways. Pain. 156: 305-17. PMID 25599452 DOI: 10.1097/01.J.Pain.0000460311.71572.5F |
0.457 |
|
2015 |
Bambico FR, Lacoste B, Hattan PR, Gobbi G. Father absence in the monogamous california mouse impairs social behavior and modifies dopamine and glutamate synapses in the medial prefrontal cortex. Cerebral Cortex (New York, N.Y. : 1991). 25: 1163-75. PMID 24304503 DOI: 10.1093/Cercor/Bht310 |
0.681 |
|
2014 |
Domínguez-López S, Howell RD, López-Canúl MG, Leyton M, Gobbi G. Electrophysiological characterization of dopamine neuronal activity in the ventral tegmental area across the light-dark cycle. Synapse (New York, N.Y.). 68: 454-67. PMID 24955825 DOI: 10.1002/Syn.21757 |
0.368 |
|
2014 |
Rainer Q, Speziali S, Rubino T, Dominguez-Lopez S, Bambico FR, Gobbi G, Parolaro D. Chronic nandrolone decanoate exposure during adolescence affects emotional behavior and monoaminergic neurotransmission in adulthood. Neuropharmacology. 83: 79-88. PMID 24721625 DOI: 10.1016/J.Neuropharm.2014.03.015 |
0.792 |
|
2014 |
Ochoa-Sanchez R, Comai S, Spadoni G, Bedini A, Tarzia G, Gobbi G. Melatonin, selective and non-selective MT1/MT2 receptors agonists: differential effects on the 24-h vigilance states. Neuroscience Letters. 561: 156-61. PMID 24406151 DOI: 10.1016/J.Neulet.2013.12.069 |
0.375 |
|
2014 |
Comai S, Gobbi G. Unveiling the role of melatonin MT2 receptors in sleep, anxiety and other neuropsychiatric diseases: a novel target in psychopharmacology. Journal of Psychiatry & Neuroscience : Jpn. 39: 6-21. PMID 23971978 DOI: 10.1503/Jpn.130009 |
0.393 |
|
2014 |
Comai S, Ochoa-Sanchez R, Gobbi G. P.1.g.109 Distinct role of melatonin MT1 and MT2 receptors in sleep and anxiety: insights from melatonin receptor knockout mice European Neuropsychopharmacology. 24: S268. DOI: 10.1016/S0924-977X(14)70420-1 |
0.379 |
|
2014 |
Gobbi G, Comai S, Ochoa-Sanchez R. S.27.01 Novel selective melatonin MT2 receptor agonist in the treatment of insomnia European Neuropsychopharmacology. 24: S144. DOI: 10.1016/S0924-977X(14)70210-X |
0.391 |
|
2013 |
Comai S, Ochoa-Sanchez R, Gobbi G. Sleep-wake characterization of double MTâ‚/MTâ‚‚ receptor knockout mice and comparison with MTâ‚ and MTâ‚‚ receptor knockout mice. Behavioural Brain Research. 243: 231-8. PMID 23333399 DOI: 10.1016/J.Bbr.2013.01.008 |
0.369 |
|
2012 |
DomÃnguez-López S, Howell R, Gobbi G. Characterization of serotonin neurotransmission in knockout mice: implications for major depression. Reviews in the Neurosciences. 23: 429-43. PMID 23089640 DOI: 10.1515/Revneuro-2012-0044 |
0.441 |
|
2012 |
Ochoa-Sanchez R, Rainer Q, Comai S, Spadoni G, Bedini A, Rivara S, Fraschini F, Mor M, Tarzia G, Gobbi G. Anxiolytic effects of the melatonin MT(2) receptor partial agonist UCM765: comparison with melatonin and diazepam. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 39: 318-25. PMID 22789661 DOI: 10.1016/J.Pnpbp.2012.07.003 |
0.758 |
|
2012 |
Morales-Medina JC, Dominguez-Lopez S, Gobbi G, Beck-Sickinger AG, Quirion R. The selective neuropeptide Y Y5 agonist [cPP(1-7),NPY(19-23),Ala31,Aib32,Gln34]hPP differently modulates emotional processes and body weight in the rat. Behavioural Brain Research. 233: 298-304. PMID 22613731 DOI: 10.1016/J.Bbr.2012.05.015 |
0.373 |
|
2012 |
Bambico FR, Hattan PR, Garant JP, Gobbi G. Effect of delta-9-tetrahydrocannabinol on behavioral despair and on pre- and postsynaptic serotonergic transmission. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 38: 88-96. PMID 22386778 DOI: 10.1016/J.Pnpbp.2012.02.006 |
0.774 |
|
2012 |
Comai S, Tau M, Pavlovic Z, Gobbi G. The psychopharmacology of aggressive behavior: a translational approach: part 2: clinical studies using atypical antipsychotics, anticonvulsants, and lithium. Journal of Clinical Psychopharmacology. 32: 237-60. PMID 22367663 DOI: 10.1097/Jcp.0B013E31824929D6 |
0.328 |
|
2012 |
McLaughlin RJ, Hill MN, Bambico FR, Stuhr KL, Gobbi G, Hillard CJ, Gorzalka BB. Prefrontal cortical anandamide signaling coordinates coping responses to stress through a serotonergic pathway. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 22: 664-71. PMID 22325231 DOI: 10.1016/J.Euroneuro.2012.01.004 |
0.783 |
|
2012 |
Comai S, Tau M, Gobbi G. The psychopharmacology of aggressive behavior: a translational approach: part 1: neurobiology. Journal of Clinical Psychopharmacology. 32: 83-94. PMID 22198449 DOI: 10.1097/Jcp.0B013E31823F8770 |
0.364 |
|
2012 |
Labonte B, McLaughlin RJ, Dominguez-Lopez S, Bambico FR, Lucchino I, Ochoa-Sanchez R, Leyton M, Gobbi G. Adolescent amphetamine exposure elicits dose-specific effects on monoaminergic neurotransmission and behaviour in adulthood. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 1319-30. PMID 22053980 DOI: 10.1017/S1461145711001544 |
0.792 |
|
2012 |
McLaughlin RJ, Gobbi G. Cannabinoids and emotionality: a neuroanatomical perspective. Neuroscience. 204: 134-44. PMID 21827834 DOI: 10.1016/J.Neuroscience.2011.07.052 |
0.646 |
|
2012 |
DomÃnguez-López S, Mahar I, Bambico FR, Labonté B, Ochoa-Sánchez R, Leyton M, Gobbi G. Short-term effects of melatonin and pinealectomy on serotonergic neuronal activity across the light-dark cycle. Journal of Psychopharmacology (Oxford, England). 26: 830-44. PMID 21730015 DOI: 10.1177/0269881111408460 |
0.771 |
|
2011 |
Ochoa-Sanchez R, Comai S, Lacoste B, Bambico FR, Dominguez-Lopez S, Spadoni G, Rivara S, Bedini A, Angeloni D, Fraschini F, Mor M, Tarzia G, Descarries L, Gobbi G. Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 18439-52. PMID 22171046 DOI: 10.1523/Jneurosci.2676-11.2011 |
0.723 |
|
2011 |
Cassano T, Gaetani S, Macheda T, Laconca L, Romano A, Morgese MG, Cimmino CS, Chiarotti F, Bambico FR, Gobbi G, Cuomo V, Piomelli D. Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice. Psychopharmacology. 214: 465-76. PMID 21042794 DOI: 10.1007/S00213-010-2051-0 |
0.7 |
|
2011 |
Ochoa-Sanchez R, Comai S, Gobbi G. M-B-035 SLEEP IN MT2 MELATONIN RECEPTOR KNOCKOUT MICE Sleep Medicine. 12: S32. DOI: 10.1016/S1389-9457(11)70113-7 |
0.312 |
|
2010 |
Bambico FR, Cassano T, Dominguez-Lopez S, Katz N, Walker CD, Piomelli D, Gobbi G. Genetic deletion of fatty acid amide hydrolase alters emotional behavior and serotonergic transmission in the dorsal raphe, prefrontal cortex, and hippocampus. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2083-100. PMID 20571484 DOI: 10.1038/Npp.2010.80 |
0.753 |
|
2010 |
Mazella J, Pétrault O, Lucas G, Deval E, Béraud-Dufour S, Gandin C, El-Yacoubi M, Widmann C, Guyon A, Chevet E, Taouji S, Conductier G, Corinus A, Coppola T, Gobbi G, et al. Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design. Plos Biology. 8: e1000355. PMID 20405001 DOI: 10.1371/Journal.Pbio.1000355 |
0.434 |
|
2010 |
Bambico FR, Nguyen NT, Katz N, Gobbi G. Chronic exposure to cannabinoids during adolescence but not during adulthood impairs emotional behaviour and monoaminergic neurotransmission. Neurobiology of Disease. 37: 641-55. PMID 19969082 DOI: 10.1016/J.Nbd.2009.11.020 |
0.731 |
|
2009 |
Hill MN, Hillard CJ, Bambico FR, Patel S, Gorzalka BB, Gobbi G. The therapeutic potential of the endocannabinoid system for the development of a novel class of antidepressants. Trends in Pharmacological Sciences. 30: 484-93. PMID 19732971 DOI: 10.1016/J.Tips.2009.06.006 |
0.768 |
|
2009 |
Rivara S, Vacondio F, Fioni A, Silva C, Carmi C, Mor M, Lucini V, Pannacci M, Caronno A, Scaglione F, Gobbi G, Spadoni G, Bedini A, Orlando P, Lucarini S, et al. N-(Anilinoethyl)amides: design and synthesis of metabolically stable, selective melatonin receptor ligands. Chemmedchem. 4: 1746-55. PMID 19728346 DOI: 10.1002/Cmdc.200900240 |
0.361 |
|
2009 |
Labonte B, Bambico FR, Gobbi G. Potentiation of excitatory serotonergic responses by MK-801 in the medial prefrontal cortex. Naunyn-Schmiedeberg's Archives of Pharmacology. 380: 383-97. PMID 19727675 DOI: 10.1007/S00210-009-0446-4 |
0.743 |
|
2009 |
Bambico FR, Duranti A, Tontini A, Tarzia G, Gobbi G. Endocannabinoids in the treatment of mood disorders: evidence from animal models. Current Pharmaceutical Design. 15: 1623-46. PMID 19442178 DOI: 10.2174/138161209788168029 |
0.754 |
|
2009 |
Blier P, Gobbi G, Turcotte JE, de Montigny C, Boucher N, Hébert C, Debonnel G. Mirtazapine and paroxetine in major depression: a comparison of monotherapy versus their combination from treatment initiation. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 19: 457-65. PMID 19345072 DOI: 10.1016/J.Euroneuro.2009.01.015 |
0.501 |
|
2009 |
Cassano T, Gaetani S, Morgese MG, Macheda T, Laconca L, Dipasquale P, Taltavull J, Shippenberg TS, Cuomo V, Gobbi G. Monoaminergic changes in locus coeruleus and dorsal raphe nucleus following noradrenaline depletion. Neurochemical Research. 34: 1417-26. PMID 19229609 DOI: 10.1007/S11064-009-9928-5 |
0.354 |
|
2009 |
Bambico FR, Nguyen NT, Gobbi G. Decline in serotonergic firing activity and desensitization of 5-HT1A autoreceptors after chronic unpredictable stress. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 19: 215-28. PMID 19147333 DOI: 10.1016/J.Euroneuro.2008.11.005 |
0.739 |
|
2008 |
Di Marzo V, Gobbi G, Szallasi A. Brain TRPV1: a depressing TR(i)P down memory lane? Trends in Pharmacological Sciences. 29: 594-600. PMID 18947889 DOI: 10.1016/J.Tips.2008.09.004 |
0.416 |
|
2008 |
Bambico FR, Gobbi G. The cannabinoid CB1 receptor and the endocannabinoid anandamide: possible antidepressant targets. Expert Opinion On Therapeutic Targets. 12: 1347-66. PMID 18851692 DOI: 10.1517/14728222.12.11.1347 |
0.745 |
|
2008 |
Berney A, Nishikawa M, Benkelfat C, Debonnel G, Gobbi G, Diksic M. An index of 5-HT synthesis changes during early antidepressant treatment: alpha-[11C]methyl-L-tryptophan PET study. Neurochemistry International. 52: 701-8. PMID 17928105 DOI: 10.1016/J.Neuint.2007.08.021 |
0.415 |
|
2007 |
Rivara S, Lodola A, Mor M, Bedini A, Spadoni G, Lucini V, Pannacci M, Fraschini F, Scaglione F, Sanchez RO, Gobbi G, Tarzia G. N-(substituted-anilinoethyl)amides: design, synthesis, and pharmacological characterization of a new class of melatonin receptor ligands. Journal of Medicinal Chemistry. 50: 6618-26. PMID 18052314 DOI: 10.1021/Jm700957J |
0.358 |
|
2007 |
Bambico FR, Katz N, Debonnel G, Gobbi G. Cannabinoids elicit antidepressant-like behavior and activate serotonergic neurons through the medial prefrontal cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11700-11. PMID 17959812 DOI: 10.1523/Jneurosci.1636-07.2007 |
0.773 |
|
2007 |
Gobbi G, Cassano T, Radja F, Morgese MG, Cuomo V, Santarelli L, Hen R, Blier P. Neurokinin 1 receptor antagonism requires norepinephrine to increase serotonin function. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 17: 328-38. PMID 16950604 DOI: 10.1016/J.Euroneuro.2006.07.004 |
0.599 |
|
2006 |
Heurteaux C, Lucas G, Guy N, El Yacoubi M, Thümmler S, Peng XD, Noble F, Blondeau N, Widmann C, Borsotto M, Gobbi G, Vaugeois JM, Debonnel G, Lazdunski M. Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype. Nature Neuroscience. 9: 1134-41. PMID 16906152 DOI: 10.1038/Nn1749 |
0.391 |
|
2006 |
Gobbi G, Janiri L. Sodium- and magnesium-valproate in vivo modulate glutamatergic and GABAergic synapses in the medial prefrontal cortex. Psychopharmacology. 185: 255-62. PMID 16496131 DOI: 10.1007/S00213-006-0317-3 |
0.376 |
|
2005 |
Gobbi G, Bambico FR, Mangieri R, Bortolato M, Campolongo P, Solinas M, Cassano T, Morgese MG, Debonnel G, Duranti A, Tontini A, Tarzia G, Mor M, Trezza V, Goldberg SR, et al. Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis. Proceedings of the National Academy of Sciences of the United States of America. 102: 18620-5. PMID 16352709 DOI: 10.1073/Pnas.0509591102 |
0.75 |
|
2005 |
Gobbi G. Serotonin firing activity as a marker for mood disorders: lessons from knockout mice. International Review of Neurobiology. 65: 249-72. PMID 16140059 DOI: 10.1016/S0074-7742(04)65009-4 |
0.47 |
|
2005 |
Gobbi G, Blier P. Effect of neurokinin-1 receptor antagonists on serotoninergic, noradrenergic and hippocampal neurons: comparison with antidepressant drugs. Peptides. 26: 1383-93. PMID 16042978 DOI: 10.1016/J.Peptides.2005.03.032 |
0.622 |
|
2004 |
Blier P, Gobbi G, Haddjeri N, Santarelli L, Mathew G, Hen R. Impact of substance P receptor antagonism on the serotonin and norepinephrine systems: relevance to the antidepressant/anxiolytic response. Journal of Psychiatry & Neuroscience : Jpn. 29: 208-18. PMID 15173897 |
0.583 |
|
2003 |
Gobbi G, Slater S, Boucher N, Debonnel G, Blier P. Neurochemical and psychotropic effects of bupropion in healthy male subjects. Journal of Clinical Psychopharmacology. 23: 233-9. PMID 12826985 DOI: 10.1097/01.Jcp.0000084023.22282.03 |
0.588 |
|
2002 |
Santarelli L, Gobbi G, Blier P, Hen R. Behavioral and physiologic effects of genetic or pharmacologic inactivation of the substance P receptor (NK1). The Journal of Clinical Psychiatry. 63: 11-7. PMID 12562138 |
0.539 |
|
2001 |
Gobbi G, Muntoni AL, Gessa GL, Diana M. Clonidine fails to modify dopaminergic neuronal activity during morphine withdrawal. Psychopharmacology. 158: 1-6. PMID 11685378 DOI: 10.1007/S002130100832 |
0.787 |
|
2001 |
Gobbi G, Murphy DL, Lesch K, Blier P. Modifications of the serotonergic system in mice lacking serotonin transporters: an in vivo electrophysiological study. The Journal of Pharmacology and Experimental Therapeutics. 296: 987-95. PMID 11181933 |
0.319 |
|
2001 |
Santarelli L, Gobbi G, Debs PC, Sibille ET, Blier P, Hen R, Heath MJ. Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function. Proceedings of the National Academy of Sciences of the United States of America. 98: 1912-7. PMID 11172050 DOI: 10.1073/Pnas.98.4.1912 |
0.629 |
|
2000 |
Debonnel G, Gobbi G, Turcotte J, Boucher N, Hébert C, De Montigny C, Blier P. Effects of mirtazapine, paroxetine and their combination: a double-blind study in major depression European Neuropsychopharmacology. 10: 252. DOI: 10.1016/S0924-977X(00)80213-8 |
0.484 |
|
1999 |
Gobbi G, Janiri L. Clozapine blocks dopamine, 5-HT2 and 5-HT3 responses in the medial prefrontal cortex: An in vivo microiontophoretic study European Neuropsychopharmacology. 10: 43-49. PMID 10647096 DOI: 10.1016/S0924-977X(99)00055-3 |
0.472 |
|
1994 |
Janiri L, Gobbi G, Persico AM, Santarelli M, Minciacchi D, Tempesta E. Alterations of neocortical neuronal responses to acetylcholine and gaba in rats born to alcohol-dependent mothers Alcohol and Alcoholism. 29: 611-619. PMID 7811346 DOI: 10.1093/Oxfordjournals.Alcalc.A045591 |
0.309 |
|
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