Joachim Herz, MD - Publications

Affiliations: 
Molecular Genetics University of Texas Southwestern Medical Center, Dallas, TX, United States 
Area:
cholesterol metabolism, Alzheimer's

154 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Xian X, Pohlkamp T, Durakoglugil MS, Wong CH, Beck JK, Lane-Donovan C, Plattner F, Herz J. Reversal of ApoE4 induced recycling block as a novel prevention approach for Alzheimer's disease. Elife. 7. PMID 30375977 DOI: 10.7554/eLife.40048  0.84
2018 Hamlin AN, Chinnarasu S, Ding Y, Xian X, Herz J, Jaeschke A, Hui DY. Low density lipoprotein receptor-related protein-1 dysfunction synergizes with dietary cholesterol to accelerate steatohepatitis progression. The Journal of Biological Chemistry. PMID 29752404 DOI: 10.1074/jbc.RA118.001952  0.32
2017 Xian X, Ding Y, Dieckmann M, Zhou L, Plattner F, Liu M, Parks JS, Hammer RE, Boucher P, Tsai S, Herz J. LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis. Elife. 6. PMID 29144234 DOI: 10.7554/eLife.29292  0.52
2017 Lane-Donovan C, Herz J. Building a better blood-brain barrier. Elife. 6. PMID 28994392 DOI: 10.7554/eLife.31808  0.84
2017 Evers BM, Rodriguez-Navas C, Tesla RJ, Prange-Kiel J, Wasser CR, Yoo KS, McDonald J, Cenik B, Ravenscroft TA, Plattner F, Rademakers R, Yu G, White CL, Herz J. Lipidomic and Transcriptomic Basis of Lysosomal Dysfunction in Progranulin Deficiency. Cell Reports. 20: 2565-2574. PMID 28903038 DOI: 10.1016/j.celrep.2017.08.056  0.32
2017 Kounnas MZ, Lane-Donovan C, Nowakowski DW, Herz J, Comer WT. NGP 555, a γ-Secretase Modulator, Lowers the Amyloid Biomarker, Aβ42, in Cerebrospinal Fluid while Preventing Alzheimer's Disease Cognitive Decline in Rodents. Alzheimer's & Dementia (New York, N. Y.). 3: 65-73. PMID 28497107 DOI: 10.1016/j.trci.2016.09.003  0.84
2017 Pohlkamp T, Wasser CR, Herz J. Functional Roles of the Interaction of APP and Lipoprotein Receptors. Frontiers in Molecular Neuroscience. 10: 54. PMID 28298885 DOI: 10.3389/fnmol.2017.00054  0.32
2017 Lane-Donovan C, Herz J. The ApoE receptors Vldlr and Apoer2 in Central Nervous System Function and Disease. Journal of Lipid Research. PMID 28292942 DOI: 10.1194/jlr.R075507  0.84
2017 Lane-Donovan C, Herz J. ApoE, ApoE Receptors, and the Synapse in Alzheimer's Disease. Trends in Endocrinology and Metabolism: Tem. PMID 28057414 DOI: 10.1016/j.tem.2016.12.001  0.84
2016 Wasser CR, Herz J. Reelin: Neurodevelopmental Architect and Homeostatic Regulator of Excitatory Synapses. The Journal of Biological Chemistry. PMID 27994051 DOI: 10.1074/jbc.R116.766782  0.32
2016 Lane-Donovan C, Wong WM, Durakoglugil MS, Wasser CR, Jiang S, Xian X, Herz J. Genetic Restoration of Plasma ApoE Improves Cognition and Partially Restores Synaptic Defects in ApoE-Deficient Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 10141-50. PMID 27683909 DOI: 10.1523/JNEUROSCI.1054-16.2016  1
2016 Nicholson AM, Finch NA, Almeida M, Perkerson RB, van Blitterswijk M, Wojtas A, Cenik B, Rotondo S, Inskeep V, Almasy L, Dyer T, Peralta J, Jun G, Wood AR, Frayling TM, ... ... Herz J, et al. Prosaposin is a regulator of progranulin levels and oligomerization. Nature Communications. 7: 11992. PMID 27356620 DOI: 10.1038/ncomms11992  1
2016 Ding Y, Xian X, Holland WL, Tsai S, Herz J. Low-Density Lipoprotein Receptor-Related Protein-1 Protects Against Hepatic Insulin Resistance and Hepatic Steatosis. Ebiomedicine. 7: 135-145. PMID 27322467 DOI: 10.1016/j.ebiom.2016.04.002  1
2016 Lane-Donovan C, Desai C, Pohlkamp T, Plautz EJ, Herz J, Stowe AM. Physiologic Reelin does not play a strong role in protection against acute stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 27146512 DOI: 10.1177/0271678X16646386  0.84
2016 Ding Y, Huang L, Xian X, Yuhanna IS, Wasser CR, Frotscher M, Mineo C, Shaul PW, Herz J. Loss of Reelin protects against atherosclerosis by reducing leukocyte-endothelial cell adhesion and lesion macrophage accumulation. Science Signaling. 9: ra29. PMID 26980442 DOI: 10.1126/scisignal.aad5578  1
2016 Wasser CR, Herz J. Splicing therapeutics for Alzheimer's disease. Embo Molecular Medicine. PMID 26902203 DOI: 10.15252/emmm.201506067  1
2016 Lane-Donovan C, Herz J. High-Fat Diet Changes Hippocampal Apolipoprotein E (ApoE) in a Genotype- and Carbohydrate-Dependent Manner in Mice. Plos One. 11: e0148099. PMID 26828652 DOI: 10.1371/journal.pone.0148099  1
2015 Ulrich V, Gelber SE, Vukelic M, Sacharidou A, Herz J, Urbanus RT, de Groot PG, Natale DR, Harihara A, Redecha P, Abrahams VM, Shaul PW, Salmon JE, Mineo C. ApoE Receptor 2 mediates trophoblast dysfunction and pregnancy complications induced by antiphospholipid antibodies in mice. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26474194 DOI: 10.1002/art.39453  1
2015 Eldridge S, Nalesso G, Ismail H, Vicente-Greco K, Kabouridis P, Ramachandran M, Niemeier A, Herz J, Pitzalis C, Perretti M, Dell'Accio F. Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo. Annals of the Rheumatic Diseases. PMID 26290588 DOI: 10.1136/annrheumdis-2015-207316  1
2015 Lane-Donovan C, Philips GT, Wasser CR, Durakoglugil MS, Masiulis I, Upadhaya A, Pohlkamp T, Coskun C, Kotti T, Steller L, Hammer RE, Frotscher M, Bock HH, Herz J. Reelin protects against amyloid β toxicity in vivo. Science Signaling. 8: ra67. PMID 26152694 DOI: 10.1126/scisignal.aaa6674  1
2015 Suh J, Moncaster JA, Wang L, Hafeez I, Herz J, Tanzi RE, Goldstein LE, Guénette SY. FE65 and FE65L1 amyloid precursor protein-binding protein compound null mice display adult-onset cataract and muscle weakness. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 2628-39. PMID 25757569 DOI: 10.1096/fj.14-261453  1
2015 Pohlkamp T, Durakoglugil M, Lane-Donovan C, Xian X, Johnson EB, Hammer RE, Herz J. Lrp4 domains differentially regulate limb/brain development and synaptic plasticity. Plos One. 10: e0116701. PMID 25688974 DOI: 10.1371/journal.pone.0116701  1
2014 Chakraborty S, Li L, Puliyappadamba VT, Guo G, Hatanpaa KJ, Mickey B, Souza RF, Vo P, Herz J, Chen MR, Boothman DA, Pandita TK, Wang DH, Sen GC, Habib AA. Constitutive and ligand-induced EGFR signalling triggers distinct and mutually exclusive downstream signalling networks. Nature Communications. 5: 5811. PMID 25503978 DOI: 10.1038/ncomms6811  1
2014 Wasser CR, Masiulis I, Durakoglugil MS, Lane-Donovan C, Xian X, Beffert U, Agarwala A, Hammer RE, Herz J. Differential splicing and glycosylation of Apoer2 alters synaptic plasticity and fear learning. Science Signaling. 7: ra113. PMID 25429077 DOI: 10.1126/scisignal.2005438  1
2014 Nakajima C, Haffner P, Goerke SM, Zurhove K, Adelmann G, Frotscher M, Herz J, Bock HH, May P. The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular development. Development (Cambridge, England). 141: 4513-25. PMID 25377550 DOI: 10.1242/dev.109124  1
2014 Ulrich V, Konaniah ES, Lee WR, Khadka S, Shen YM, Herz J, Salmon JE, Hui DY, Shaul PW, Mineo C. Antiphospholipid antibodies attenuate endothelial repair and promote neointima formation in mice. Journal of the American Heart Association. 3: e001369. PMID 25315347 DOI: 10.1161/JAHA.114.001369  1
2014 Ulrich V, Konaniah ES, Herz J, Gerard RD, Jung E, Yuhanna IS, Ahmed M, Hui DY, Mineo C, Shaul PW. Genetic variants of ApoE and ApoER2 differentially modulate endothelial function. Proceedings of the National Academy of Sciences of the United States of America. 111: 13493-8. PMID 25197062 DOI: 10.1073/pnas.1402106111  1
2014 Ward ME, Taubes A, Chen R, Miller BL, Sephton CF, Gelfand JM, Minami S, Boscardin J, Martens LH, Seeley WW, Yu G, Herz J, Filiano AJ, Arrant AE, Roberson ED, et al. Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD. The Journal of Experimental Medicine. 211: 1937-45. PMID 25155018 DOI: 10.1084/jem.20140214  1
2014 Lane-Donovan C, Philips GT, Herz J. More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration. Neuron. 83: 771-87. PMID 25144875 DOI: 10.1016/j.neuron.2014.08.005  1
2014 Lane-Donovan C, Herz J. Is apolipoprotein e required for cognitive function in humans?: implications for Alzheimer drug development. Jama Neurology. 71: 1213-5. PMID 25110920 DOI: 10.1001/jamaneurol.2014.2013  1
2014 Pohlkamp T, Steller L, May P, Günther T, Schüle R, Frotscher M, Herz J, Bock HH. Generation and characterization of an Nse-CreERT2 transgenic line suitable for inducible gene manipulation in cerebellar granule cells. Plos One. 9: e100384. PMID 24950299 DOI: 10.1371/journal.pone.0100384  1
2014 Schorch B, Song S, van Diemen FR, Bock HH, May P, Herz J, Brummelkamp TR, Papatheodorou P, Aktories K. LRP1 is a receptor for Clostridium perfringens TpeL toxin indicating a two-receptor model of clostridial glycosylating toxins. Proceedings of the National Academy of Sciences of the United States of America. 111: 6431-6. PMID 24737893 DOI: 10.1073/pnas.1323790111  1
2014 Prabhudas M, Bowdish D, Drickamer K, Febbraio M, Herz J, Kobzik L, Krieger M, Loike J, Means TK, Moestrup SK, Post S, Sawamura T, Silverstein S, Wang XY, El Khoury J. Standardizing scavenger receptor nomenclature. Journal of Immunology (Baltimore, Md. : 1950). 192: 1997-2006. PMID 24563502 DOI: 10.4049/jimmunol.1490003  1
2014 Subramanian M, Hayes CD, Thome JJ, Thorp E, Matsushima GK, Herz J, Farber DL, Liu K, Lakshmana M, Tabas I. An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo. The Journal of Clinical Investigation. 124: 1296-308. PMID 24509082 DOI: 10.1172/JCI72051  1
2014 Gilat-Frenkel M, Boehm-Cagan A, Liraz O, Xian X, Herz J, Michaelson DM. Involvement of the Apoer2 and Lrp1 receptors in mediating the pathological effects of ApoE4 in vivo. Current Alzheimer Research. 11: 549-57. PMID 24251389 DOI: 10.2174/1567205010666131119232444  1
2014 Pohlkamp T, Dávid C, Cauli B, Gallopin T, Bouché E, Karagiannis A, May P, Herz J, Frotscher M, Staiger JF, Bock HH. Characterization and distribution of Reelin-positive interneuron subtypes in the rat barrel cortex. Cerebral Cortex (New York, N.Y. : 1991). 24: 3046-58. PMID 23803971 DOI: 10.1093/cercor/bht161  1
2014 Wasser CR, Herz J, VanHook AM. Science Signaling podcast: 25 November 2014 Science Signaling. 7. DOI: 10.1126/scisignal.aaa1326  1
2013 Bal M, Leitz J, Reese AL, Ramirez DM, Durakoglugil M, Herz J, Monteggia LM, Kavalali ET. Reelin mobilizes a VAMP7-dependent synaptic vesicle pool and selectively augments spontaneous neurotransmission. Neuron. 80: 934-46. PMID 24210904 DOI: 10.1016/j.neuron.2013.08.024  1
2013 Choi HY, Liu Y, Tennert C, Sugiura Y, Karakatsani A, Kröger S, Johnson EB, Hammer RE, Lin W, Herz J. APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice. Elife. 2: e00220. PMID 23986861 DOI: 10.7554/eLife.00220  1
2013 Brunne B, Franco S, Bouché E, Herz J, Howell BW, Pahle J, Müller U, May P, Frotscher M, Bock HH. Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by Reelin signaling mutant mice. Glia. 61: 1347-63. PMID 23828756 DOI: 10.1002/glia.22519  1
2013 Nakajima C, Kulik A, Frotscher M, Herz J, Schäfer M, Bock HH, May P. Low density lipoprotein receptor-related protein 1 (LRP1) modulates N-methyl-D-aspartate (NMDA) receptor-dependent intracellular signaling and NMDA-induced regulation of postsynaptic protein complexes. The Journal of Biological Chemistry. 288: 21909-23. PMID 23760271 DOI: 10.1074/jbc.M112.444364  1
2013 Chen X, Chang J, Deng Q, Xu J, Nguyen TA, Martens LH, Cenik B, Taylor G, Hudson KF, Chung J, Yu K, Yu P, Herz J, Farese RV, Kukar T, et al. Progranulin does not bind tumor necrosis factor (TNF) receptors and is not a direct regulator of TNF-dependent signaling or bioactivity in immune or neuronal cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9202-13. PMID 23699531 DOI: 10.1523/JNEUROSCI.5336-12.2013  1
2013 Nguyen AD, Nguyen TA, Cenik B, Yu G, Herz J, Walther TC, Davidson WS, Farese RV. Secreted progranulin is a homodimer and is not a component of high density lipoproteins (HDL). The Journal of Biological Chemistry. 288: 8627-35. PMID 23364791 DOI: 10.1074/jbc.M112.441949  1
2013 Bouché E, Romero-Ortega MI, Henkemeyer M, Catchpole T, Leemhuis J, Frotscher M, May P, Herz J, Bock HH. Reelin induces EphB activation. Cell Research. 23: 473-90. PMID 23318582 DOI: 10.1038/cr.2013.7  1
2013 Carlo AS, Gustafsen C, Mastrobuoni G, Nielsen MS, Burgert T, Hartl D, Rohe M, Nykjaer A, Herz J, Heeren J, Kempa S, Petersen CM, Willnow TE. The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 358-70. PMID 23283348 DOI: 10.1523/JNEUROSCI.2425-12.2013  1
2013 Dieckmann M, Beil FT, Mueller B, Bartelt A, Marshall RP, Koehne T, Amling M, Ruether W, Cooper JA, Humphries SE, Herz J, Niemeier A. Human apolipoprotein E isoforms differentially affect bone mass and turnover in vivo. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 236-45. PMID 22991192 DOI: 10.1002/jbmr.1757  1
2012 Sekine K, Kawauchi T, Kubo K, Honda T, Herz J, Hattori M, Kinashi T, Nakajima K. Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin α5β1. Neuron. 76: 353-69. PMID 23083738 DOI: 10.1016/j.neuron.2012.07.020  1
2012 Woldt E, Terrand J, Mlih M, Matz RL, Bruban V, Coudane F, Foppolo S, El Asmar Z, Chollet ME, Ninio E, Bednarczyk A, Thiersé D, Schaeffer C, Van Dorsselaer A, Boudier C, ... ... Herz J, et al. The nuclear hormone receptor PPARγ counteracts vascular calcification by inhibiting Wnt5a signalling in vascular smooth muscle cells. Nature Communications. 3: 1077. PMID 23011131 DOI: 10.1038/ncomms2087  1
2012 Sephton CF, Cenik B, Cenik BK, Herz J, Yu G. TDP-43 in central nervous system development and function: clues to TDP-43-associated neurodegeneration. Biological Chemistry. 393: 589-94. PMID 22944662 DOI: 10.1515/hsz-2012-0115  1
2012 Du Y, Yang M, Wei W, Huynh HD, Herz J, Saghatelian A, Wan Y. Macrophage VLDL receptor promotes PAFAH secretion in mother's milk and suppresses systemic inflammation in nursing neonates. Nature Communications. 3: 1008. PMID 22910354 DOI: 10.1038/ncomms2011  1
2012 Cenik B, Sephton CF, Kutluk Cenik B, Herz J, Yu G. Progranulin: a proteolytically processed protein at the crossroads of inflammation and neurodegeneration. The Journal of Biological Chemistry. 287: 32298-306. PMID 22859297 DOI: 10.1074/jbc.R112.399170  1
2012 Dewey CM, Cenik B, Sephton CF, Johnson BA, Herz J, Yu G. TDP-43 aggregation in neurodegeneration: are stress granules the key? Brain Research. 1462: 16-25. PMID 22405725 DOI: 10.1016/j.brainres.2012.02.032  1
2012 Holtzman DM, Herz J, Bu G. Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease. Cold Spring Harbor Perspectives in Medicine. 2: a006312. PMID 22393530 DOI: 10.1101/cshperspect.a006312  1
2012 Dries DR, Yu G, Herz J. Extracting β-amyloid from Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 109: 3199-200. PMID 22328154 DOI: 10.1073/pnas.1121560109  1
2012 Porntaveetus T, Ohazama A, Choi HY, Herz J, Sharpe PT. Wnt signaling in the murine diastema. European Journal of Orthodontics. 34: 518-24. PMID 21531785 DOI: 10.1093/ejo/cjr049  1
2011 Trotter JH, Klein M, Jinwal UK, Abisambra JF, Dickey CA, Tharkur J, Masiulis I, Ding J, Locke KG, Rickman CB, Birch DG, Weeber EJ, Herz J. ApoER2 function in the establishment and maintenance of retinal synaptic connectivity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14413-23. PMID 21976526 DOI: 10.1523/JNEUROSCI.3135-11.2011  1
2011 Woldt E, Matz RL, Terrand J, Mlih M, Gracia C, Foppolo S, Martin S, Bruban V, Ji J, Velot E, Herz J, Boucher P. Differential signaling by adaptor molecules LRP1 and ShcA regulates adipogenesis by the insulin-like growth factor-1 receptor. The Journal of Biological Chemistry. 286: 16775-82. PMID 21454706 DOI: 10.1074/jbc.M110.212878  1
2011 Cenik B, Sephton CF, Dewey CM, Xian X, Wei S, Yu K, Niu W, Coppola G, Coughlin SE, Lee SE, Dries DR, Almeida S, Geschwind DH, Gao FB, Miller BL, ... ... Herz J, et al. Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia. The Journal of Biological Chemistry. 286: 16101-8. PMID 21454553 DOI: 10.1074/jbc.M110.193433  1
2011 Haas J, Beer AG, Widschwendter P, Oberdanner J, Salzmann K, Sarg B, Lindner H, Herz J, Patsch JR, Marschang P. LRP1b shows restricted expression in human tissues and binds to several extracellular ligands, including fibrinogen and apoE-carrying lipoproteins. Atherosclerosis. 216: 342-7. PMID 21420681 DOI: 10.1016/j.atherosclerosis.2011.02.030  1
2011 Nagajyothi F, Weiss LM, Silver DL, Desruisseaux MS, Scherer PE, Herz J, Tanowitz HB. Trypanosoma cruzi utilizes the host low density lipoprotein receptor in invasion. Plos Neglected Tropical Diseases. 5: e953. PMID 21408103 DOI: 10.1371/journal.pntd.0000953  1
2011 Baitsch D, Bock HH, Engel T, Telgmann R, Müller-Tidow C, Varga G, Bot M, Herz J, Robenek H, von Eckardstein A, Nofer JR. Apolipoprotein E induces antiinflammatory phenotype in macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1160-8. PMID 21350196 DOI: 10.1161/ATVBAHA.111.222745  1
2011 Long H, Bock HH, Lei T, Chai X, Yuan J, Herz J, Frotscher M, Yang Z. Identification of alternatively spliced Dab1 and Fyn isoforms in pig. Bmc Neuroscience. 12: 17. PMID 21294906 DOI: 10.1186/1471-2202-12-17  1
2011 Liu Q, Zhang J, Zerbinatti C, Zhan Y, Kolber BJ, Herz J, Muglia LJ, Bu G. Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system. Plos Biology. 9: e1000575. PMID 21264353 DOI: 10.1371/journal.pbio.1000575  1
2011 Dewey CM, Cenik B, Sephton CF, Dries DR, Mayer P, Good SK, Johnson BA, Herz J, Yu G. TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor. Molecular and Cellular Biology. 31: 1098-108. PMID 21173160 DOI: 10.1128/MCB.01279-10  1
2011 Ramesh S, Morrell CN, Tarango C, Thomas GD, Yuhanna IS, Girardi G, Herz J, Urbanus RT, de Groot PG, Thorpe PE, Salmon JE, Shaul PW, Mineo C. Antiphospholipid antibodies promote leukocyte-endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via β2GPI and apoER2. The Journal of Clinical Investigation. 121: 120-31. PMID 21123944 DOI: 10.1172/JCI39828  1
2011 Boucher P, Herz J. Signaling through LRP1: Protection from atherosclerosis and beyond. Biochemical Pharmacology. 81: 1-5. PMID 20920479 DOI: 10.1016/j.bcp.2010.09.018  1
2010 Ohazama A, Porntaveetus T, Ota MS, Herz J, Sharpe PT. Lrp4: A novel modulator of extracellular signaling in craniofacial organogenesis. American Journal of Medical Genetics. Part A. 152: 2974-83. PMID 21108386 DOI: 10.1002/ajmg.a.33372  1
2010 Leemhuis J, Bouché E, Frotscher M, Henle F, Hein L, Herz J, Meyer DK, Pichler M, Roth G, Schwan C, Bock HH. Reelin signals through apolipoprotein E receptor 2 and Cdc42 to increase growth cone motility and filopodia formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14759-72. PMID 21048135 DOI: 10.1523/JNEUROSCI.4036-10.2010  1
2010 Dieckmann M, Dietrich MF, Herz J. Lipoprotein receptors--an evolutionarily ancient multifunctional receptor family. Biological Chemistry. 391: 1341-63. PMID 20868222 DOI: 10.1515/BC.2010.129  1
2010 Brunne B, Zhao S, Derouiche A, Herz J, May P, Frotscher M, Bock HH. Origin, maturation, and astroglial transformation of secondary radial glial cells in the developing dentate gyrus. Glia. 58: 1553-69. PMID 20549747 DOI: 10.1002/glia.21029  1
2010 Chen Y, Durakoglugil MS, Xian X, Herz J. ApoE4 reduces glutamate receptor function and synaptic plasticity by selectively impairing ApoE receptor recycling. Proceedings of the National Academy of Sciences of the United States of America. 107: 12011-6. PMID 20547867 DOI: 10.1073/pnas.0914984107  1
2010 Förster E, Bock HH, Herz J, Chai X, Frotscher M, Zhao S. Emerging topics in Reelin function. The European Journal of Neuroscience. 31: 1511-8. PMID 20525064 DOI: 10.1111/j.1460-9568.2010.07222.x  1
2010 Karner CM, Dietrich MF, Johnson EB, Kappesser N, Tennert C, Percin F, Wollnik B, Carroll TJ, Herz J. Lrp4 regulates initiation of ureteric budding and is crucial for kidney formation--a mouse model for Cenani-Lenz syndrome. Plos One. 5: e10418. PMID 20454682 DOI: 10.1371/journal.pone.0010418  1
2010 Dietrich MF, van der Weyden L, Prosser HM, Bradley A, Herz J, Adams DJ. Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo. Plos One. 5: e9960. PMID 20383322 DOI: 10.1371/journal.pone.0009960  1
2010 Li Y, Pawlik B, Elcioglu N, Aglan M, Kayserili H, Yigit G, Percin F, Goodman F, Nürnberg G, Cenani A, Urquhart J, Chung BD, Ismail S, Amr K, Aslanger AD, ... ... Herz J, et al. LRP4 mutations alter Wnt/beta-catenin signaling and cause limb and kidney malformations in Cenani-Lenz syndrome. American Journal of Human Genetics. 86: 696-706. PMID 20381006 DOI: 10.1016/j.ajhg.2010.03.004  1
2010 Sephton CF, Good SK, Atkin S, Dewey CM, Mayer P, Herz J, Yu G. TDP-43 is a developmentally regulated protein essential for early embryonic development. The Journal of Biological Chemistry. 285: 6826-34. PMID 20040602 DOI: 10.1074/jbc.M109.061846  1
2010 Ohazama A, Blackburn J, Porntaveetus T, Ota MS, Choi HY, Johnson EB, Myers P, Oommen S, Eto K, Kessler JA, Kondo T, Fraser GJ, Streelman JT, Pardiñas UF, Tucker AS, ... ... Herz J, et al. A role for suppressed incisor cuspal morphogenesis in the evolution of mammalian heterodont dentition. Proceedings of the National Academy of Sciences of the United States of America. 107: 92-7. PMID 20018657 DOI: 10.1073/pnas.0907236107  1
2010 Jedrychowski MP, Gartner CA, Gygi SP, Zhou L, Herz J, Kandror KV, Pilch PF. Proteomic analysis of GLUT4 storage vesicles reveals LRP1 to be an important vesicle component and target of insulin signaling. The Journal of Biological Chemistry. 285: 104-14. PMID 19864425 DOI: 10.1074/jbc.M109.040428  1
2010 Sephton CF, Good SK, Atkin S, Dewey CM, Mayer P, Herz J, Yu G. TDP-43 is a developmentally regulated protein essential for early embryonic development (Journal of Biological Chemistry (2010) 285, (6826-6834)) Journal of Biological Chemistry. 285: 38740. DOI: 10.1074/jbc.A109.061846  1
2009 Choi HY, Dieckmann M, Herz J, Niemeier A. Lrp4, a novel receptor for Dickkopf 1 and sclerostin, is expressed by osteoblasts and regulates bone growth and turnover in vivo. Plos One. 4: e7930. PMID 19936252 DOI: 10.1371/journal.pone.0007930  1
2009 Durakoglugil MS, Chen Y, White CL, Kavalali ET, Herz J. Reelin signaling antagonizes beta-amyloid at the synapse. Proceedings of the National Academy of Sciences of the United States of America. 106: 15938-43. PMID 19805234 DOI: 10.1073/pnas.0908176106  1
2009 Zhou L, Takayama Y, Boucher P, Tallquist MD, Herz J. LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation. Plos One. 4: e6922. PMID 19742316 DOI: 10.1371/journal.pone.0006922  1
2009 Basford JE, Moore ZW, Zhou L, Herz J, Hui DY. Smooth muscle LDL receptor-related protein-1 inactivation reduces vascular reactivity and promotes injury-induced neointima formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1772-8. PMID 19729608 DOI: 10.1161/ATVBAHA.109.194357  1
2009 Zhou L, Choi HY, Li WP, Xu F, Herz J. LRP1 controls cPLA2 phosphorylation, ABCA1 expression and cellular cholesterol export. Plos One. 4: e6853. PMID 19718435 DOI: 10.1371/journal.pone.0006853  1
2009 Herz J. Apolipoprotein E receptors in the nervous system. Current Opinion in Lipidology. 20: 190-6. PMID 19433918 DOI: 10.1097/MOL.0b013e32832d3a10  1
2009 Boycott KM, Bonnemann C, Herz J, Neuert S, Beaulieu C, Scott JN, Venkatasubramanian A, Parboosingh JS. Mutations in VLDLR as a cause for autosomal recessive cerebellar ataxia with mental retardation (dysequilibrium syndrome). Journal of Child Neurology. 24: 1310-5. PMID 19332571 DOI: 10.1177/0883073809332696  1
2009 Herz J, Chen Y, Masiulis I, Zhou L. Expanding functions of lipoprotein receptors. Journal of Lipid Research. 50: S287-92. PMID 19017612 DOI: 10.1194/jlr.R800077-JLR200  1
2009 Masiulis I, Quill TA, Burk RF, Herz J. Differential functions of the Apoer2 intracellular domain in selenium uptake and cell signaling. Biological Chemistry. 390: 67-73. PMID 19007311 DOI: 10.1515/BC.2009.011  1
2009 Terrand J, Bruban V, Zhou L, Gong W, El Asmar Z, May P, Zurhove K, Haffner P, Philippe C, Woldt E, Matz RL, Gracia C, Metzger D, Auwerx J, Herz J, et al. LRP1 controls intracellular cholesterol storage and fatty acid synthesis through modulation of Wnt signaling. The Journal of Biological Chemistry. 284: 381-8. PMID 18990694 DOI: 10.1074/jbc.M806538200  1
2009 Mitnala S, Huebshman M, Herold C, Herz J, Garner H. High Precision Spatial and Temporal control of neural circuitry using a semi-automated, multi-wavelength nanopatterning system Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7180. DOI: 10.1117/12.809171  1
2008 Ohazama A, Johnson EB, Ota MS, Choi HY, Choi HJ, Porntaveetus T, Oommen S, Itoh N, Eto K, Gritli-Linde A, Herz J, Sharpe PT. Lrp4 modulates extracellular integration of cell signaling pathways in development. Plos One. 3: e4092. PMID 19116665 DOI: 10.1371/journal.pone.0004092  1
2008 Zurhove K, Nakajima C, Herz J, Bock HH, May P. Gamma-secretase limits the inflammatory response through the processing of LRP1. Science Signaling. 1: ra15. PMID 19036715 DOI: 10.1126/scisignal.1164263  1
2008 Herz J, Boycott KM, Parboosingh JS. "Devolution" of bipedality. Proceedings of the National Academy of Sciences of the United States of America. 105: E25. PMID 18487453 DOI: 10.1073/pnas.0802584105  1
2008 Lukowski R, Weinmeister P, Bernhard D, Feil S, Gotthardt M, Herz J, Massberg S, Zernecke A, Weber C, Hofmann F, Feil R. Role of smooth muscle cGMP/cGKI signaling in murine vascular restenosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1244-50. PMID 18420996 DOI: 10.1161/ATVBAHA.108.166405  1
2008 Larouche M, Beffert U, Herz J, Hawkes R. The Reelin receptors Apoer2 and Vldlr coordinate the patterning of Purkinje cell topography in the developing mouse cerebellum. Plos One. 3: e1653. PMID 18301736 DOI: 10.1371/journal.pone.0001653  1
2008 Akopians AL, Babayan AH, Beffert U, Herz J, Basbaum AI, Phelps PE. Contribution of the Reelin signaling pathways to nociceptive processing. The European Journal of Neuroscience. 27: 523-37. PMID 18279306 DOI: 10.1111/j.1460-9568.2008.06056.x  1
2008 Bock HH, Herz J. Apolipoprotein e receptor 2 and very-low-density lipoprotein receptor: An overview Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease. 15-35. DOI: 10.1007/978-0-387-76761-1_2  1
2007 Hofmann SM, Zhou L, Perez-Tilve D, Greer T, Grant E, Wancata L, Thomas A, Pfluger PT, Basford JE, Gilham D, Herz J, Tschöp MH, Hui DY. Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice. The Journal of Clinical Investigation. 117: 3271-82. PMID 17948131 DOI: 10.1172/JCI31929  1
2007 Liu Q, Zerbinatti CV, Zhang J, Hoe HS, Wang B, Cole SL, Herz J, Muglia L, Bu G. Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1. Neuron. 56: 66-78. PMID 17920016 DOI: 10.1016/j.neuron.2007.08.008  1
2007 Boucher P, Li WP, Matz RL, Takayama Y, Auwerx J, Anderson RG, Herz J. LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome. Plos One. 2: e448. PMID 17505534 DOI: 10.1371/journal.pone.0000448  1
2007 Zhang G, Assadi AH, McNeil RS, Beffert U, Wynshaw-Boris A, Herz J, Clark GD, D'Arcangelo G. The Pafah1b complex interacts with the reelin receptor VLDLR. Plos One. 2: e252. PMID 17330141 DOI: 10.1371/journal.pone.0000252  1
2007 Herz J. Overview: the long and winding road to understanding Alzheimer's disease. Neuron. 53: 477-9. PMID 17296548 DOI: 10.1016/j.neuron.2007.02.001  1
2007 Bock HH, Herz J, May P. Conditional animal models for the study of lipid metabolism and lipid disorders Handbook of Experimental Pharmacology. 178: 407-439. PMID 17203665 DOI: 10.1007/978-3-540-35109-2-17  1
2007 Jones C, Garuti R, Michaely P, Li WP, Maeda N, Cohen JC, Herz J, Hobbs HH. Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia. The Journal of Clinical Investigation. 117: 165-74. PMID 17200716 DOI: 10.1172/JCI29415  1
2006 Beffert U, Nematollah Farsian F, Masiulis I, Hammer RE, Yoon SO, Giehl KM, Herz J. ApoE receptor 2 controls neuronal survival in the adult brain. Current Biology : Cb. 16: 2446-52. PMID 17174920 DOI: 10.1016/j.cub.2006.10.029  1
2006 Herz J, Chen Y. Reelin, lipoprotein receptors and synaptic plasticity. Nature Reviews. Neuroscience. 7: 850-9. PMID 17053810 DOI: 10.1038/nrn2009  1
2006 Hu L, Boesten LSM, May P, Herz J, Bovenschen N, Huisman MV, Berbée JFP, Havekes LM, Van Vlijmen BJM, Tamsma JT. Macrophage low-density lipoprotein receptor-related protein deficiency enhances atherosclerosis in apoE/LDLR double knockout mice Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 2710-2715. PMID 17038633 DOI: 10.1161/01.ATV.0000249641.96896.e6  1
2006 Johnson EB, Steffen DJ, Lynch KW, Herz J. Defective splicing of Megf7/Lrp4, a regulator of distal limb development, in autosomal recessive mulefoot disease. Genomics. 88: 600-9. PMID 16963222 DOI: 10.1016/j.ygeno.2006.08.005  1
2006 Herz J. The switch on the RAPper's necklace... Molecular Cell. 23: 451-5. PMID 16916634 DOI: 10.1016/j.molcel.2006.07.026  1
2006 Li X, Herz J, Monard D. Activation of ERK signaling upon alternative protease nexin-1 internalization mediated by syndecan-1. Journal of Cellular Biochemistry. 99: 936-51. PMID 16741952 DOI: 10.1002/jcb.20881  1
2006 Cao C, Lawrence DA, Li Y, Von Arnim CA, Herz J, Su EJ, Makarova A, Hyman BT, Strickland DK, Zhang L. Endocytic receptor LRP together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migration. The Embo Journal. 25: 1860-70. PMID 16601674 DOI: 10.1038/sj.emboj.7601082  1
2006 Beffert U, Durudas A, Weeber EJ, Stolt PC, Giehl KM, Sweatt JD, Hammer RE, Herz J. Functional dissection of Reelin signaling by site-directed disruption of Disabled-1 adaptor binding to apolipoprotein E receptor 2: distinct roles in development and synaptic plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2041-52. PMID 16481437 DOI: 10.1523/JNEUROSCI.4566-05.2006  1
2006 Guénette S, Chang Y, Hiesberger T, Richardson JA, Eckman CB, Eckman EA, Hammer RE, Herz J. Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development. The Embo Journal. 25: 420-31. PMID 16407979 DOI: 10.1038/sj.emboj.7600926  1
2005 Johnson EB, Hammer RE, Herz J. Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice. Human Molecular Genetics. 14: 3523-38. PMID 16207730 DOI: 10.1093/hmg/ddi381  1
2005 Garuti R, Jones C, Li WP, Michaely P, Herz J, Gerard RD, Cohen JC, Hobbs HH. The modular adaptor protein autosomal recessive hypercholesterolemia (ARH) promotes low density lipoprotein receptor clustering into clathrin-coated pits. The Journal of Biological Chemistry. 280: 40996-1004. PMID 16179341 DOI: 10.1074/jbc.M509394200  1
2005 May P, Herz J, Bock HH. Molecular mechanisms of lipoprotein receptor signalling Cellular and Molecular Life Sciences. 62: 2325-2338. PMID 16158188 DOI: 10.1007/s00018-005-5231-z  1
2005 Chen Y, Beffert U, Ertunc M, Tang TS, Kavalali ET, Bezprozvanny I, Herz J. Reelin modulates NMDA receptor activity in cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8209-16. PMID 16148228 DOI: 10.1523/JNEUROSCI.1951-05.2005  1
2005 Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P, McGuinness OP, Chikuda H, Yamaguchi M, Kawaguchi H, Shimomura I, Takayama Y, Herz J, Kahn CR, Rosenblatt KP, et al. Suppression of aging in mice by the hormone Klotho. Science (New York, N.Y.). 309: 1829-33. PMID 16123266 DOI: 10.1126/science.1112766  1
2005 Beffert U, Weeber EJ, Durudas A, Qiu S, Masiulis I, Sweatt JD, Li WP, Adelmann G, Frotscher M, Hammer RE, Herz J. Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2. Neuron. 47: 567-79. PMID 16102539 DOI: 10.1016/j.neuron.2005.07.007  1
2005 Takayama Y, May P, Anderson RG, Herz J. Low density lipoprotein receptor-related protein 1 (LRP1) controls endocytosis and c-CBL-mediated ubiquitination of the platelet-derived growth factor receptor beta (PDGFR beta). The Journal of Biological Chemistry. 280: 18504-10. PMID 15753096 DOI: 10.1074/jbc.M410265200  1
2005 Shigematsu H, Lin L, Takahashi T, Nomura M, Suzuki M, Wistuba II, Fong KM, Lee H, Toyooka S, Shimizu N, Fujisawa T, Feng Z, Roth JA, Herz J, Minna JD, et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. Journal of the National Cancer Institute. 97: 339-46. PMID 15741570 DOI: 10.1093/jnci/dji055  1
2005 Aiyer AR, Honarpour N, Herz J, Srivastava D. Loss of Apaf-1 leads to partial rescue of the HAND2-null phenotype. Developmental Biology. 278: 155-62. PMID 15649468 DOI: 10.1016/j.ydbio.2004.11.001  1
2005 Stolt PC, Chen Y, Liu P, Bock HH, Blacklow SC, Herz J. Phosphoinositide binding by the disabled-1 PTB domain is necessary for membrane localization and Reelin signal transduction. The Journal of Biological Chemistry. 280: 9671-7. PMID 15632144 DOI: 10.1074/jbc.M413356200  1
2005 Petit-Turcotte C, Aumont N, Beffert U, Dea D, Herz J, Poirier J. The apoE receptor apoER2 is involved in the maintenance of efficient synaptic plasticity. Neurobiology of Aging. 26: 195-206. PMID 15582748 DOI: 10.1016/j.neurobiolaging.2004.04.007  1
2004 Gazdar AF, Shigematsu H, Herz J, Minna JD. Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers? Trends in Molecular Medicine. 10: 481-6. PMID 15464447 DOI: 10.1016/j.molmed.2004.08.008  1
2004 May P, Rohlmann A, Bock HH, Zurhove K, Marth JD, Schomburg ED, Noebels JL, Beffert U, Sweatt JD, Weeber EJ, Herz J. Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice. Molecular and Cellular Biology. 24: 8872-83. PMID 15456862 DOI: 10.1128/MCB.24.20.8872-8883.2004  1
2004 Minna JD, Gazdar AF, Sprang SR, Herz J. Cancer. A bull's eye for targeted lung cancer therapy. Science (New York, N.Y.). 304: 1458-61. PMID 15178790 DOI: 10.1126/science.1099578  1
2004 Bock HH, Jossin Y, May P, Bergner O, Herz J. Apolipoprotein E receptors are required for reelin-induced proteasomal degradation of the neuronal adaptor protein Disabled-1. The Journal of Biological Chemistry. 279: 33471-9. PMID 15175346 DOI: 10.1074/jbc.M401770200  1
2004 Marschang P, Brich J, Weeber EJ, Sweatt JD, Shelton JM, Richardson JA, Hammer RE, Herz J. Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1. Molecular and Cellular Biology. 24: 3782-93. PMID 15082773 DOI: 10.1128/MCB.24.9.3782-3793.2004  1
2004 Herz J, Hui DY. Lipoprotein receptors in the vascular wall. Current Opinion in Lipidology. 15: 175-81. PMID 15017360 DOI: 10.1097/00041433-200404000-00010  1
2004 Beffert U, Weeber EJ, Morfini G, Ko J, Brady ST, Tsai LH, Sweatt JD, Herz J. Reelin and cyclin-dependent kinase 5-dependent signals cooperate in regulating neuronal migration and synaptic transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1897-906. PMID 14985430 DOI: 10.1523/JNEUROSCI.4084-03.2004  1
2004 Espirito Santo SM, Pires NM, Boesten LS, Gerritsen G, Bovenschen N, van Dijk KW, Jukema JW, Princen HM, Bensadoun A, Li WP, Herz J, Havekes LM, van Vlijmen BJ. Hepatic low-density lipoprotein receptor-related protein deficiency in mice increases atherosclerosis independent of plasma cholesterol. Blood. 103: 3777-82. PMID 14739216 DOI: 10.1182/blood-2003-11-4051  1
2004 Strasser V, Fasching D, Hauser C, Mayer H, Bock HH, Hiesberger T, Herz J, Weeber EJ, Sweatt JD, Pramatarova A, Howell B, Schneider WJ, Nimpf J. Receptor clustering is involved in Reelin signaling. Molecular and Cellular Biology. 24: 1378-86. PMID 14729980 DOI: 10.1128/MCB.24.3.1378-1386.2004  1
2004 Jossin Y, Ignatova N, Hiesberger T, Herz J, Lambert de Rouvroit C, Goffinet AM. The central fragment of Reelin, generated by proteolytic processing in vivo, is critical to its function during cortical plate development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 514-21. PMID 14724251 DOI: 10.1523/JNEUROSCI.3408-03.2004  1
2004 Vergés M, Bensadoun A, Herz J, Belcher JD, Havel RJ. Endocytosis of hepatic lipase and lipoprotein lipase into rat liver hepatocytes in vivo is mediated by the low density lipoprotein receptor-related protein. The Journal of Biological Chemistry. 279: 9030-6. PMID 14701798 DOI: 10.1074/jbc.M312908200  1
2004 Beffert U, Stolt PC, Herz J. Functions of lipoprotein receptors in neurons. Journal of Lipid Research. 45: 403-9. PMID 14657206 DOI: 10.1194/jlr.R300017-JLR200  1
2003 Herz J. LRP: a bright beacon at the blood-brain barrier. The Journal of Clinical Investigation. 112: 1483-5. PMID 14617749 DOI: 10.1172/JCI20337  1
2003 Assadi AH, Zhang G, Beffert U, McNeil RS, Renfro AL, Niu S, Quattrocchi CC, Antalffy BA, Sheldon M, Armstrong DD, Wynshaw-Boris A, Herz J, D'Arcangelo G, Clark GD. Interaction of reelin signaling and Lis1 in brain development. Nature Genetics. 35: 270-6. PMID 14578885 DOI: 10.1038/ng1257  1
2002 Beffert U, Morfini G, Bock HH, Reyna H, Brady ST, Herz J. Reelin-mediated signaling locally regulates protein kinase B/Akt and glycogen synthase kinase 3beta. The Journal of Biological Chemistry. 277: 49958-64. PMID 12376533 DOI: 10.1074/jbc.M209205200  1
2002 Weeber EJ, Beffert U, Jones C, Christian JM, Forster E, Sweatt JD, Herz J. Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning. The Journal of Biological Chemistry. 277: 39944-52. PMID 12167620 DOI: 10.1074/jbc.M205147200  1
2000 Herz J, Beffert U. Apolipoprotein E receptors: linking brain development and Alzheimer's disease. Nature Reviews. Neuroscience. 1: 51-8. PMID 11252768 DOI: 10.1038/35036221  1
1997 Shimano H, Shimomura I, Hammer RE, Herz J, Goldstein JL, Brown MS, Horton JD. Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene. The Journal of Clinical Investigation. 100: 2115-24. PMID 9329978 DOI: 10.1172/JCI119746  1
1997 Brown MS, Herz J, Goldstein JL. LDL-receptor structure. Calcium cages, acid baths and recycling receptors. Nature. 388: 629-30. PMID 9262394 DOI: 10.1038/41672  1
1995 Frykman PK, Brown MS, Yamamoto T, Goldstein JL, Herz J. Normal plasma lipoproteins and fertility in gene-targeted mice homozygous for a disruption in the gene encoding very low density lipoprotein receptor. Proceedings of the National Academy of Sciences of the United States of America. 92: 8453-7. PMID 7667310  1
1994 Ishibashi S, Herz J, Maeda N, Goldstein JL, Brown MS. The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins. Proceedings of the National Academy of Sciences of the United States of America. 91: 4431-5. PMID 8183926  1
1994 Ishibashi S, Goldstein JL, Brown MS, Herz J, Burns DK. Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice. The Journal of Clinical Investigation. 93: 1885-93. PMID 8182121 DOI: 10.1172/JCI117179  1
1993 Ishibashi S, Brown MS, Goldstein JL, Gerard RD, Hammer RE, Herz J. Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. The Journal of Clinical Investigation. 92: 883-93. PMID 8349823 DOI: 10.1172/JCI116663  1
1992 Willnow TE, Goldstein JL, Orth K, Brown MS, Herz J. Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance. The Journal of Biological Chemistry. 267: 26172-80. PMID 1464627  1
1991 Herz J, Goldstein JL, Strickland DK, Ho YK, Brown MS. 39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor. The Journal of Biological Chemistry. 266: 21232-8. PMID 1718973  1
1990 Kowal RC, Herz J, Weisgraber KH, Mahley RW, Brown MS, Goldstein JL. Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein. The Journal of Biological Chemistry. 265: 10771-9. PMID 2355022  1
1990 Weisgraber KH, Mahley RW, Kowal RC, Herz J, Goldstein JL, Brown MS. Apolipoprotein C-I modulates the interaction of apolipoprotein E with beta-migrating very low density lipoproteins (beta-VLDL) and inhibits binding of beta-VLDL to low density lipoprotein receptor-related protein. The Journal of Biological Chemistry. 265: 22453-9. PMID 2266137  1
1990 Herz J, Kowal RC, Ho YK, Brown MS, Goldstein JL. Low density lipoprotein receptor-related protein mediates endocytosis of monoclonal antibodies in cultured cells and rabbit liver. The Journal of Biological Chemistry. 265: 21355-62. PMID 2250029  1
1990 Herz J, Kowal RC, Goldstein JL, Brown MS. Proteolytic processing of the 600 kd low density lipoprotein receptor-related protein (LRP) occurs in a trans-Golgi compartment. The Embo Journal. 9: 1769-76. PMID 2112085  1
1989 Kowal RC, Herz J, Goldstein JL, Esser V, Brown MS. Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins. Proceedings of the National Academy of Sciences of the United States of America. 86: 5810-4. PMID 2762297  1
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