Evangelos Kiskinis - Publications

Northwestern University, Evanston, IL 
Cell Biology, Molecular Neuroscience, Motor Control, Neurobiology of Disease

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Mann JR, McKenna ED, Mawrie D, Papakis V, Alessandrini F, Anderson EN, Mayers R, Ball HE, Kaspi E, Lubinski K, Baron DM, Tellez L, Landers JE, Pandey UB, Kiskinis E. Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import. Science Advances. 9: eadi5548. PMID 37585529 DOI: 10.1126/sciadv.adi5548  0.328
2023 Álvarez Z, Ortega JA, Sato K, Sasselli IR, Kolberg-Edelbrock AN, Qiu R, Marshall KA, Nguyen TP, Smith CS, Quinlan KA, Papakis V, Syrgiannis Z, Sather NA, Musumeci C, Engel E, ... ... Kiskinis E, et al. Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons. Cell Stem Cell. PMID 36638801 DOI: 10.1016/j.stem.2022.12.010  0.366
2021 Simkin D, Marshall KA, Vanoye CG, Desai RR, Bustos BI, Piyevsky BN, Ortega JA, Forrest M, Robertson GL, Penzes P, Laux LC, Lubbe SJ, Millichap JJ, George AL, Kiskinis E. Dyshomeostatic modulation of Ca-activated K channels in a human neuronal model of KCNQ2 encephalopathy. Elife. 10. PMID 33544076 DOI: 10.7554/eLife.64434  0.315
2020 Wainger BJ, Macklin EA, Vucic S, McIlduff CE, Paganoni S, Maragakis NJ, Bedlack R, Goyal NA, Rutkove SB, Lange DJ, Rivner MH, Goutman SA, Ladha SS, Mauricio EA, Baloh RH, ... ... Kiskinis E, et al. Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial. Jama Neurology. PMID 33226425 DOI: 10.1001/jamaneurol.2020.4300  0.573
2020 Charlton J, Jung EJ, Mattei AL, Bailly N, Liao J, Martin EJ, Giesselmann P, Brändl B, Stamenova EK, Müller FJ, Kiskinis E, Gnirke A, Smith ZD, Meissner A. TETs compete with DNMT3 activity in pluripotent cells at thousands of methylated somatic enhancers. Nature Genetics. PMID 32514123 DOI: 10.1038/S41588-020-0639-9  0.386
2020 Ortega JA, Daley EL, Kour S, Samani M, Tellez L, Smith HS, Hall EA, Esengul YT, Tsai YH, Gendron TF, Donnelly CJ, Siddique T, Savas JN, Pandey UB, Kiskinis E. Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity. Neuron. PMID 32059759 DOI: 10.1016/J.Neuron.2020.01.020  0.41
2019 Franz CK, Joshi D, Daley EL, Grant RA, Dalamagkas K, Leung A, Finan JD, Kiskinis E. The Impact of Traumatic Brain Injury on Amyotrophic Lateral Sclerosis - From Bedside to Bench. Journal of Neurophysiology. PMID 31116639 DOI: 10.1152/Jn.00572.2018  0.419
2019 Baron DM, Matheny T, Lin YC, Leszyk JD, Kenna K, Gall KV, Santos DP, Tischbein M, Funes S, Hayward LJ, Kiskinis E, Landers JE, Parker R, Shaffer SA, Bosco DA. Quantitative proteomics identifies proteins that resist translational repression and become dysregulated in ALS-FUS. Human Molecular Genetics. PMID 30806671 DOI: 10.1093/Hmg/Ddz048  0.359
2019 Hernandez-Garcia A, Álvarez Z, Simkin D, Madhan A, Pariset E, Tantakitti F, de J Vargas-Dorantes O, Lee SS, Kiskinis E, Stupp SI. Peptide-siRNA Supramolecular Particles for Neural Cell Transfection. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 6: 1801458. PMID 30775231 DOI: 10.1002/Advs.201801458  0.317
2018 Ichida JK, Staats KA, Davis-Dusenbery BN, Clement K, Galloway KE, Babos KN, Shi Y, Son EY, Kiskinis E, Atwater N, Gu H, Gnirke A, Meissner A, Eggan K. Comparative genomic analysis of embryonic, lineage-converted, and stem cell-derived motor neurons. Development (Cambridge, England). PMID 30337375 DOI: 10.1242/Dev.168617  0.697
2018 Edelbrock AN, Àlvarez Z, Simkin D, Fyrner T, Chin SM, Sato K, Kiskinis E, Stupp SI. Supramolecular Nanostructure Activates TrkB Receptor Signaling of Neuronal Cells by Mimicking Brain-Derived Neurotrophic Factor. Nano Letters. PMID 30211565 DOI: 10.1021/Acs.Nanolett.8B02317  0.327
2018 Kiskinis E, Kralj JM, Zou P, Weinstein EN, Zhang H, Tsioras K, Wiskow O, Ortega JA, Eggan K, Cohen AE. All-Optical Electrophysiology for High-Throughput Functional Characterization of a Human iPSC-Derived Motor Neuron Model of ALS. Stem Cell Reports. PMID 29779896 DOI: 10.1016/J.Stemcr.2018.04.020  0.693
2018 Simmons CQ, Thompson CH, Cawthon BE, Westlake G, Swoboda KJ, Kiskinis E, Ess KC, George AL. Direct evidence of impaired neuronal Na/K-ATPase pump function in alternating hemiplegia of childhood. Neurobiology of Disease. 115: 29-38. PMID 29567111 DOI: 10.1016/J.Nbd.2018.03.009  0.44
2018 Ziller MJ, Ortega JA, Quinlan KA, Santos DP, Gu H, Martin EJ, Galonska C, Pop R, Maidl S, Di Pardo A, Huang M, Meltzer HY, Gnirke A, Heckman CJ, Meissner A, ... Kiskinis E, et al. Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology. Cell Stem Cell. PMID 29551301 DOI: 10.1016/J.Stem.2018.02.012  0.504
2018 Charlton J, Downing TL, Smith ZD, Gu H, Clement K, Pop R, Akopian V, Klages S, Santos DP, Tsankov AM, Timmermann B, Ziller MJ, Kiskinis E, Gnirke A, Meissner A. Global delay in nascent strand DNA methylation. Nature Structural & Molecular Biology. PMID 29531288 DOI: 10.1038/S41594-018-0046-4  0.357
2017 Mitropoulos K, Merkouri Papadima E, Xiromerisiou G, Balasopoulou A, Charalampidou K, Galani V, Zafeiri KV, Dardiotis E, Ralli S, Deretzi G, John A, Kydonopoulou K, Papadopoulou E, di Pardo A, Akcimen F, ... ... Kiskinis E, et al. Genomic variants in the FTO gene are associated with sporadic amyotrophic lateral sclerosis in Greek patients. Human Genomics. 11: 30. PMID 29216901 DOI: 10.1186/S40246-017-0126-2  0.345
2017 Burbulla LF, Song P, Mazzulli JR, Zampese E, Wong YC, Jeon S, Santos DP, Blanz J, Obermaier CD, Strojny C, Savas JN, Kiskinis E, Zhuang X, Krüger R, Surmeier DJ, et al. Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease. Science (New York, N.Y.). PMID 28882997 DOI: 10.1126/Science.Aam9080  0.326
2017 Santos DP, Kiskinis E. Generation of Spinal Motor Neurons from Human Pluripotent Stem Cells. Methods in Molecular Biology (Clifton, N.J.). 1538: 53-66. PMID 27943183 DOI: 10.1007/978-1-4939-6688-2_5  0.534
2016 Santos DP, Kiskinis E, Eggan K, Merkle FT. Comprehensive Protocols for CRISPR/Cas9-based Gene Editing in Human Pluripotent Stem Cells. Current Protocols in Stem Cell Biology. 38: 5B.6.1-5B.6.60. PMID 27532820 DOI: 10.1002/Cpsc.15  0.629
2015 Ichida JK, Kiskinis E. Probing disorders of the nervous system using reprogramming approaches. The Embo Journal. 34: 1456-77. PMID 25925386 DOI: 10.15252/Embj.201591267  0.358
2015 Schwarz-Romond T, Kiskinis E, Eggan K. Focus on induced pluripotency and cellular reprogramming. The Embo Journal. 34: 1435. PMID 25916828 DOI: 10.15252/Embj.201591615  0.54
2014 de Boer AS, Koszka K, Kiskinis E, Suzuki N, Davis-Dusenbery BN, Eggan K. Genetic validation of a therapeutic target in a mouse model of ALS. Science Translational Medicine. 6: 248ra104. PMID 25100738 DOI: 10.1126/Scitranslmed.3009351  0.687
2014 Kiskinis E, Sandoe J, Williams LA, Boulting GL, Moccia R, Wainger BJ, Han S, Peng T, Thams S, Mikkilineni S, Mellin C, Merkle FT, Davis-Dusenbery BN, Ziller M, Oakley D, et al. Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1. Cell Stem Cell. 14: 781-95. PMID 24704492 DOI: 10.1016/J.Stem.2014.03.004  0.756
2014 Wainger BJ, Kiskinis E, Mellin C, Wiskow O, Han SS, Sandoe J, Perez NP, Williams LA, Lee S, Boulting G, Berry JD, Brown RH, Cudkowicz ME, Bean BP, Eggan K, et al. Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons. Cell Reports. 7: 1-11. PMID 24703839 DOI: 10.1016/J.Celrep.2014.03.019  0.751
2014 Alami NH, Smith RB, Carrasco MA, Williams LA, Winborn CS, Han SS, Kiskinis E, Winborn B, Freibaum BD, Kanagaraj A, Clare AJ, Badders NM, Bilican B, Chaum E, Chandran S, et al. Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations. Neuron. 81: 536-43. PMID 24507191 DOI: 10.1016/J.Neuron.2013.12.018  0.639
2014 Kiskinis E, Chatzeli L, Curry E, Kaforou M, Frontini A, Cinti S, Montana G, Parker MG, Christian M. RIP140 represses the "brown-in-white" adipocyte program including a futile cycle of triacylglycerol breakdown and synthesis. Molecular Endocrinology (Baltimore, Md.). 28: 344-56. PMID 24479876 DOI: 10.1210/Me.2013-1254  0.568
2014 Kiskinis E, Sandoe J, Williams L, Boulting G, Moccia R, Wainger B, Han S, Peng T, Thams S, Mikkilineni S, Mellin C, Merkle F, Davis-Dusenbery B, Ziller M, Oakley D, et al. Pathways Disrupted in Human ALS Motor Neurons Identified through Genetic Correction of Mutant SOD1 Cell Stem Cell. 14: 873. DOI: 10.1016/J.Stem.2014.04.005  0.736
2012 Mekhoubad S, Bock C, de Boer AS, Kiskinis E, Meissner A, Eggan K. Erosion of dosage compensation impacts human iPSC disease modeling. Cell Stem Cell. 10: 595-609. PMID 22560080 DOI: 10.1016/J.Stem.2012.02.014  0.751
2011 Gore A, Li Z, Fung HL, Young JE, Agarwal S, Antosiewicz-Bourget J, Canto I, Giorgetti A, Israel MA, Kiskinis E, Lee JH, Loh YH, Manos PD, Montserrat N, Panopoulos AD, et al. Somatic coding mutations in human induced pluripotent stem cells. Nature. 471: 63-7. PMID 21368825 DOI: 10.1038/Nature09805  0.632
2011 Bock C, Kiskinis E, Verstappen G, Gu H, Boulting G, Smith ZD, Ziller M, Croft GF, Amoroso MW, Oakley DH, Gnirke A, Eggan K, Meissner A. Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines. Cell. 144: 439-52. PMID 21295703 DOI: 10.1016/J.Cell.2010.12.032  0.778
2011 Boulting GL, Kiskinis E, Croft GF, Amoroso MW, Oakley DH, Wainger BJ, Williams DJ, Kahler DJ, Yamaki M, Davidow L, Rodolfa CT, Dimos JT, Mikkilineni S, MacDermott AB, Woolf CJ, et al. A functionally characterized test set of human induced pluripotent stem cells. Nature Biotechnology. 29: 279-86. PMID 21293464 DOI: 10.1038/Nbt.1783  0.787
2010 Ichida JK, Kiskinis E, Eggan K. Shushing down the epigenetic landscape towards stem cell differentiation. Development (Cambridge, England). 137: 2455-60. PMID 20554719 DOI: 10.1242/Dev.049130  0.612
2010 Kiskinis E, Eggan K. Progress toward the clinical application of patient-specific pluripotent stem cells. The Journal of Clinical Investigation. 120: 51-9. PMID 20051636 DOI: 10.1172/Jci40553  0.633
2010 Di Giorgio F, Boulting G, Kiskinis E, De Boer S, Bobrowicz S, Eggan K. C9 Can we build a human cell based model: SMA Reproductive Biomedicine Online. 20: S3. DOI: 10.1016/S1472-6483(10)62263-8  0.742
2008 Hallberg M, Morganstein DL, Kiskinis E, Shah K, Kralli A, Dilworth SM, White R, Parker MG, Christian M. A functional interaction between RIP140 and PGC-1alpha regulates the expression of the lipid droplet protein CIDEA. Molecular and Cellular Biology. 28: 6785-95. PMID 18794372 DOI: 10.1128/Mcb.00504-08  0.56
2007 Kiskinis E, Hallberg M, Christian M, Olofsson M, Dilworth SM, White R, Parker MG. RIP140 directs histone and DNA methylation to silence Ucp1 expression in white adipocytes. The Embo Journal. 26: 4831-40. PMID 17972916 DOI: 10.1038/Sj.Emboj.7601908  0.564
2006 García-Pedrero JM, Kiskinis E, Parker MG, Belandia B. The SWI/SNF chromatin remodeling subunit BAF57 is a critical regulator of estrogen receptor function in breast cancer cells. The Journal of Biological Chemistry. 281: 22656-64. PMID 16769725 DOI: 10.1074/Jbc.M602561200  0.556
2006 Kiskinis E, García-Pedrero JM, Villaronga MA, Parker MG, Belandia B. Identification of BAF57 mutations in human breast cancer cell lines. Breast Cancer Research and Treatment. 98: 191-8. PMID 16538531 DOI: 10.1007/S10549-005-9149-9  0.596
2006 Powelka AM, Seth A, Virbasius JV, Kiskinis E, Nicoloro SM, Guilherme A, Tang X, Straubhaar J, Cherniack AD, Parker MG, Czech MP. Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes Journal of Clinical Investigation. 116: 125-136. PMID 16374519 DOI: 10.1172/Jci26040  0.549
2005 Christian M, Kiskinis E, Debevec D, Leonardsson G, White R, Parker MG. RIP140-targeted repression of gene expression in adipocytes. Molecular and Cellular Biology. 25: 9383-91. PMID 16227589 DOI: 10.1128/Mcb.25.21.9383-9391.2005  0.59
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