Year |
Citation |
Score |
2024 |
Xu H, Lotfy P, Gelb S, Pragana A, Hehnly C, Byer LIJ, Shipley FB, Zawadzki ME, Cui J, Deng L, Taylor M, Webb M, Lidov HGW, Andermann ML, Chiu IM, ... ... Lehtinen MK, et al. The choroid plexus synergizes with immune cells during neuroinflammation. Cell. PMID 39089253 DOI: 10.1016/j.cell.2024.07.002 |
0.721 |
|
2024 |
Skiba MA, Sterling SM, Rawson S, Zhang S, Xu H, Jiang H, Nemeth GR, Gilman MSA, Hurley JD, Shen P, Staus DP, Kim J, McMahon C, Lehtinen MK, Rockman HA, et al. Antibodies expand the scope of angiotensin receptor pharmacology. Nature Chemical Biology. PMID 38744986 DOI: 10.1038/s41589-024-01620-6 |
0.607 |
|
2024 |
Fame RM, Ali I, Lehtinen MK, Kanarek N, Petrova B. Optimized Mass Spectrometry Detection of Thyroid Hormones and Polar Metabolites in Rodent Cerebrospinal Fluid. Metabolites. 14. PMID 38392972 DOI: 10.3390/metabo14020079 |
0.711 |
|
2024 |
Courtney Y, Head JP, Yimer ED, Dani N, Shipley FB, Libermann TA, Lehtinen MK. A choroid plexus apocrine secretion mechanism shapes CSF proteome and embryonic brain development. Biorxiv : the Preprint Server For Biology. PMID 38260341 DOI: 10.1101/2024.01.08.574486 |
0.815 |
|
2023 |
Fame RM, Ali I, Lehtinen MK, Kanarek N, Petrova B. Optimized Mass Spectrometry Detection of Thyroid Hormones and Polar Metabolites in Rodent Cerebrospinal Fluid. Biorxiv : the Preprint Server For Biology. PMID 38116027 DOI: 10.1101/2023.12.07.570731 |
0.713 |
|
2023 |
Petrova B, Lacey TE, Culhane AJ, Cui J, Raskin A, Misra A, Lehtinen MK, Kanarek N. Metabolomics of Mouse Embryonic CSF Following Maternal Immune Activation. Biorxiv : the Preprint Server For Biology. PMID 38105934 DOI: 10.1101/2023.12.06.570507 |
0.307 |
|
2023 |
Xu H, Dugué GP, Cantaut-Belarif Y, Lejeune FX, Gupta S, Wyart C, Lehtinen MK. SCO-spondin knockout mice exhibit small brain ventricles and mild spine deformation. Fluids and Barriers of the Cns. 20: 89. PMID 38049798 DOI: 10.1186/s12987-023-00491-8 |
0.695 |
|
2023 |
Skiba MA, Sterling SM, Rawson S, Gilman MSA, Xu H, Nemeth GR, Hurley JD, Shen P, Staus DP, Kim J, McMahon C, Lehtinen MK, Wingler LM, Kruse AC. Antibodies Expand the Scope of Angiotensin Receptor Pharmacology. Biorxiv : the Preprint Server For Biology. PMID 37662341 DOI: 10.1101/2023.08.23.554128 |
0.608 |
|
2023 |
Xu H, Lotfy P, Gelb S, Pragana A, Hehnly C, Shipley FB, Zawadzki ME, Cui J, Deng L, Taylor M, Webb M, Lidov HGW, Andermann ML, Chiu IM, Ordovas-Montanes J, ... Lehtinen MK, et al. A collaboration between immune cells and the choroid plexus epithelium in brain inflammation. Biorxiv : the Preprint Server For Biology. PMID 37609192 DOI: 10.1101/2023.08.07.552298 |
0.719 |
|
2023 |
Xu H, Dugué GP, Cantaut-Belarif Y, Lejeune FX, Gupta S, Wyart C, Lehtinen MK. SCO-spondin knockout mice exhibit small brain ventricles and mild spine deformation. Biorxiv : the Preprint Server For Biology. PMID 37577601 DOI: 10.1101/2023.08.01.551512 |
0.695 |
|
2023 |
Gelb S, Lehtinen MK. Snapshot: Choroid plexus brain barrier. Cell. 186: 3522-3522.e1. PMID 37541203 DOI: 10.1016/j.cell.2023.07.015 |
0.347 |
|
2023 |
Fame RM, Kalugin PN, Petrova B, Xu H, Soden PA, Shipley FB, Dani N, Grant B, Pragana A, Head JP, Gupta S, Shannon ML, Chifamba FF, Hawks-Mayer H, Vernon A, ... ... Lehtinen MK, et al. Defining diurnal fluctuations in mouse choroid plexus and CSF at high molecular, spatial, and temporal resolution. Nature Communications. 14: 3720. PMID 37349305 DOI: 10.1038/s41467-023-39326-3 |
0.784 |
|
2023 |
Fame RM, Xu H, Pragana A, Lehtinen M. Age-appropriate potassium clearance from perinatal cerebrospinal fluid depends on choroid plexus NKCC1. Fluids and Barriers of the Cns. 20: 45. PMID 37328833 DOI: 10.1186/s12987-023-00438-z |
0.798 |
|
2023 |
Sadegh C, Xu H, Sutin J, Fatou B, Gupta S, Pragana A, Taylor M, Kalugin PN, Zawadzki ME, Alturkistani O, Shipley FB, Dani N, Fame RM, Wurie Z, Talati P, ... ... Lehtinen MK, et al. Choroid plexus-targeted NKCC1 overexpression to treat post-hemorrhagic hydrocephalus. Neuron. PMID 36893755 DOI: 10.1016/j.neuron.2023.02.020 |
0.776 |
|
2023 |
Karimy JK, Newville JC, Sadegh C, Morris JA, Monuki ES, Limbrick DD, McAllister Ii JP, Koschnitzky JE, Lehtinen MK, Jantzie LL. Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus". Fluids and Barriers of the Cns. 20: 4. PMID 36639792 DOI: 10.1186/s12987-023-00406-7 |
0.769 |
|
2022 |
Saunders NR, Dziegielewska KM, Fame RM, Lehtinen MK, Liddelow SA. The choroid plexus: a missing link in our understanding of brain development and function. Physiological Reviews. PMID 36173801 DOI: 10.1152/physrev.00060.2021 |
0.729 |
|
2022 |
Li Q, Han Z, Singh N, Terré B, Fame RM, Arif U, Page TD, Zahran T, Abdeltawab A, Huang Y, Cao P, Wang J, Lu H, Lidov HGW, Surendran K, ... ... Lehtinen MK, et al. Disruption of GMNC-MCIDAS multiciliogenesis program is critical in choroid plexus carcinoma development. Cell Death and Differentiation. PMID 35322202 DOI: 10.1038/s41418-022-00950-z |
0.694 |
|
2022 |
Kaiser K, Jang A, Kompanikova P, Lun MP, Prochazka J, Machon O, Dani N, Prochazkova M, Laurent B, Gyllborg D, van Amerongen R, Fame RM, Gupta S, Wu F, Barker RA, ... ... Lehtinen MK, et al. Correction: MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus. Development (Cambridge, England). 149. PMID 35119069 DOI: 10.1242/dev.200517 |
0.692 |
|
2021 |
Fame RM, Lehtinen MK. Mitochondria in Early Forebrain Development: From Neurulation to Mid-Corticogenesis. Frontiers in Cell and Developmental Biology. 9: 780207. PMID 34888312 DOI: 10.3389/fcell.2021.780207 |
0.695 |
|
2021 |
Cui J, Xu H, Lehtinen MK. Macrophages on the margin: choroid plexus immune responses. Trends in Neurosciences. PMID 34312005 DOI: 10.1016/j.tins.2021.07.002 |
0.675 |
|
2021 |
Kaiser K, Jang A, Kompanikova P, Lun MP, Prochazka J, Machon O, Dani N, Prochazkova M, Laurent B, Gyllborg D, van Amerongen R, Fame RM, Gupta S, Wu F, Barker RA, ... ... Lehtinen MK, et al. MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus. Development (Cambridge, England). 148. PMID 34032267 DOI: 10.1242/dev.192054 |
0.729 |
|
2021 |
Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, ... ... Lehtinen MK, et al. A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. PMID 33932339 DOI: 10.1016/j.cell.2021.04.003 |
0.8 |
|
2021 |
Xu H, Fame RM, Sadegh C, Sutin J, Naranjo C, Della Syau, Cui J, Shipley FB, Vernon A, Gao F, Zhang Y, Holtzman MJ, Heiman M, Warf BC, Lin PY, ... Lehtinen MK, et al. Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development. Nature Communications. 12: 447. PMID 33469018 DOI: 10.1038/s41467-020-20666-3 |
0.785 |
|
2020 |
Cui J, Shipley FB, Shannon ML, Alturkistani O, Dani N, Webb MD, Sugden AU, Andermann ML, Lehtinen MK. Inflammation of the Embryonic Choroid Plexus Barrier following Maternal Immune Activation. Developmental Cell. PMID 33038331 DOI: 10.1016/j.devcel.2020.09.020 |
0.316 |
|
2020 |
Shipley FB, Dani N, Xu H, Deister C, Cui J, Head JP, Sadegh C, Fame RM, Shannon ML, Flores VI, Kishkovich T, Jang E, Klein EM, Goldey GJ, He K, ... ... Lehtinen MK, et al. Tracking Calcium Dynamics and Immune Surveillance at the Choroid Plexus Blood-Cerebrospinal Fluid Interface. Neuron. PMID 32961128 DOI: 10.1016/J.Neuron.2020.08.024 |
0.752 |
|
2020 |
Xu H, Lehtinen MK. Choroid Plexus Organoids: Harnessing CSF Gatekeepers for Brain Therapeutics. Cell Stem Cell. 27: 191-192. PMID 32763178 DOI: 10.1016/J.Stem.2020.07.009 |
0.712 |
|
2020 |
Xu H, Lehtinen MK. Cerebrospinal Fluid Magnetic Resonance Imaging: Improving Early Diagnosis of Autism and Other Neurodevelopmental Conditions. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. 5: 635-637. PMID 32646616 DOI: 10.1016/J.Bpsc.2020.05.007 |
0.651 |
|
2020 |
Fame RM, Lehtinen MK. Emergence and Developmental Roles of the Cerebrospinal Fluid System. Developmental Cell. 52: 261-275. PMID 32049038 DOI: 10.1016/J.Devcel.2020.01.027 |
0.75 |
|
2019 |
Fame RM, Shannon ML, Chau KF, Head JP, Lehtinen MK. Concerted metabolic shift in early forebrain alters the CSF proteome and depends on cMYC downregulation for mitochondrial maturation. Development (Cambridge, England). PMID 31575649 DOI: 10.1242/Dev.182857 |
0.766 |
|
2019 |
Lun MP, Shannon ML, Keles S, Reisli I, Luche N, Ryan D, Capuder K, Notarangelo LD, Lehtinen MK. Spatio-temporal gradient of cortical neuron death contributes to microcephaly in knock-in mouse model of ligase 4 syndrome. The American Journal of Pathology. PMID 31541646 DOI: 10.1016/J.Ajpath.2019.08.010 |
0.377 |
|
2019 |
Orefice LL, Mosko JR, Morency DT, Wells MF, Tasnim A, Mozeika SM, Ye M, Chirila AM, Emanuel AJ, Rankin G, Fame RM, Lehtinen MK, Feng G, Ginty DD. Targeting Peripheral Somatosensory Neurons to Improve Tactile-Related Phenotypes in ASD Models. Cell. 178: 867-886.e24. PMID 31398341 DOI: 10.1016/J.Cell.2019.07.024 |
0.707 |
|
2019 |
Fame RM, Lehtinen MK. Sister, Sister: Ependymal Cells and Adult Neural Stem Cells Are Separated at Birth by Geminin Family Members. Neuron. 102: 278-279. PMID 30998898 DOI: 10.1016/J.Neuron.2019.02.040 |
0.703 |
|
2019 |
Sadegh C, Xu H, Shipley F, Dani N, Lehtinen MK. Intraventricular Hemorrhage Induces Rapid Calcium Signaling and Transcriptional Changes in the Developing Choroid Plexus Neurosurgery. 66. DOI: 10.1093/Neuros/Nyz310_134 |
0.777 |
|
2018 |
Smith RS, Kenny CJ, Ganesh V, Jang A, Borges-Monroy R, Partlow JN, Hill RS, Shin T, Chen AY, Doan RN, Anttonen AK, Ignatius J, Medne L, Bönnemann CG, Hecht JL, ... ... Lehtinen MK, et al. Sodium Channel SCN3A (Na1.3) Regulation of Human Cerebral Cortical Folding and Oral Motor Development. Neuron. PMID 30146301 DOI: 10.1016/J.Neuron.2018.07.052 |
0.741 |
|
2018 |
Coulter ME, Dorobantu CM, Lodewijk GA, Delalande F, Cianferani S, Ganesh VS, Smith RS, Lim ET, Xu CS, Pang S, Wong ET, Lidov HGW, Calicchio ML, Yang E, Gonzalez DM, ... ... Lehtinen MK, et al. The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles. Cell Reports. 24: 973-986.e8. PMID 30044992 DOI: 10.1016/J.Celrep.2018.06.100 |
0.785 |
|
2018 |
Chau KF, Shannon ML, Fame RM, Fonseca E, Mullan H, Johnson MB, Sendamarai AK, Springel MW, Laurent B, Lehtinen MK. Downregulation of ribosome biogenesis during early forebrain development. Elife. 7. PMID 29745900 DOI: 10.7554/Elife.36998 |
0.764 |
|
2018 |
Shannon ML, Fame RM, Chau KF, Dani N, Calicchio ML, Géléoc GS, Lidov HGW, Alexandrescu S, Lehtinen MK. Mice Expressing c-MYC in Neural Precursors Develop Choroid Plexus and Ciliary Body Tumors. The American Journal of Pathology. PMID 29545198 DOI: 10.1016/J.Ajpath.2018.02.009 |
0.701 |
|
2018 |
Chau KF, Shannon ML, Fame RM, Fonseca E, Mullan H, Johnson MB, Sendamarai AK, Springel MW, Laurent B, Lehtinen MK. Author response: Downregulation of ribosome biogenesis during early forebrain development Elife. DOI: 10.7554/Elife.36998.018 |
0.437 |
|
2017 |
Anttonen AK, Laari A, Kousi M, Yang YJ, Jääskeläinen T, Somer M, Siintola E, Jakkula E, Muona M, Tegelberg S, Lönnqvist T, Pihko H, Valanne L, Paetau A, Lun MP, ... ... Lehtinen MK, et al. ZNHIT3 is defective in PEHO syndrome, a severe encephalopathy with cerebellar granule neuron loss. Brain : a Journal of Neurology. PMID 28335020 DOI: 10.1093/Brain/Awx040 |
0.341 |
|
2017 |
Lehtinen MK. The brain's matchmakers. Science Translational Medicine. 9. PMID 28275158 DOI: 10.1126/Scitranslmed.Aam9863 |
0.335 |
|
2017 |
Lehtinen MK. Epilepsy clocks in Science Translational Medicine. 9: eaaq1237. DOI: 10.1126/Scitranslmed.Aaq1237 |
0.309 |
|
2016 |
Dani N, Lehtinen MK. CSF Makes Waves in the Neural Stem Cell Niche. Cell Stem Cell. 19: 565-566. PMID 27814476 DOI: 10.1016/J.Stem.2016.10.008 |
0.356 |
|
2016 |
Li L, Grausam KB, Wang J, Lun MP, Ohli J, Lidov HG, Calicchio ML, Zeng E, Salisbury JL, Wechsler-Reya RJ, Lehtinen MK, Schüller U, Zhao H. Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells. Nature Cell Biology. PMID 26999738 DOI: 10.1038/Ncb3327 |
0.341 |
|
2015 |
Chau KF, Springel MW, Broadbelt KG, Park HY, Topal S, Lun MP, Mullan H, Maynard T, Steen H, LaMantia AS, Lehtinen MK. Progressive Differentiation and Instructive Capacities of Amniotic Fluid and Cerebrospinal Fluid Proteomes following Neural Tube Closure. Developmental Cell. 35: 789-802. PMID 26702835 DOI: 10.1016/J.Devcel.2015.11.015 |
0.433 |
|
2015 |
Lun MP, Monuki ES, Lehtinen MK. Development and functions of the choroid plexus-cerebrospinal fluid system. Nature Reviews. Neuroscience. 16: 445-57. PMID 26174708 DOI: 10.1038/Nrn3921 |
0.682 |
|
2015 |
Chang JT, Lehtinen MK, Sive H. Zebrafish cerebrospinal fluid mediates cell survival through a retinoid signaling pathway. Developmental Neurobiology. PMID 25980532 DOI: 10.1002/Dneu.22300 |
0.644 |
|
2015 |
Lun MP, Johnson MB, Broadbelt KG, Watanabe M, Kang YJ, Chau KF, Springel MW, Malesz A, Sousa AM, Pletikos M, Adelita T, Calicchio ML, Zhang Y, Holtzman MJ, Lidov HG, ... ... Lehtinen MK, et al. Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 4903-16. PMID 25810521 DOI: 10.1523/Jneurosci.3081-14.2015 |
0.702 |
|
2013 |
Lehtinen MK, Bjornsson CS, Dymecki SM, Gilbertson RJ, Holtzman DM, Monuki ES. The choroid plexus and cerebrospinal fluid: emerging roles in development, disease, and therapy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17553-9. PMID 24198345 DOI: 10.1523/Jneurosci.3258-13.2013 |
0.657 |
|
2013 |
Zappaterra MW, LaMantia AS, Walsh CA, Lehtinen MK. Isolation of cerebrospinal fluid from rodent embryos for use with dissected cerebral cortical explants. Journal of Visualized Experiments : Jove. e50333. PMID 23524481 DOI: 10.3791/50333 |
0.595 |
|
2012 |
Lehtinen MK. Adult neurogenesis: VCAM stems the tide. Cell Stem Cell. 11: 137-8. PMID 22862936 DOI: 10.1016/J.Stem.2012.07.012 |
0.328 |
|
2012 |
Poduri A, Evrony GD, Cai X, Elhosary PC, Beroukhim R, Lehtinen MK, Hills LB, Heinzen EL, Hill A, Hill RS, Barry BJ, Bourgeois BF, Riviello JJ, Barkovich AJ, Black PM, et al. Somatic activation of AKT3 causes hemispheric developmental brain malformations. Neuron. 74: 41-8. PMID 22500628 DOI: 10.1016/J.Neuron.2012.03.010 |
0.781 |
|
2012 |
Zappaterra MW, Lehtinen MK. The cerebrospinal fluid: regulator of neurogenesis, behavior, and beyond. Cellular and Molecular Life Sciences : Cmls. 69: 2863-78. PMID 22415326 DOI: 10.1007/S00018-012-0957-X |
0.47 |
|
2011 |
Lehtinen MK, Walsh CA. Neurogenesis at the brain-cerebrospinal fluid interface. Annual Review of Cell and Developmental Biology. 27: 653-79. PMID 21801012 DOI: 10.1146/Annurev-Cellbio-092910-154026 |
0.583 |
|
2011 |
Lehtinen MK, Zappaterra MW, Chen X, Yang YJ, Hill AD, Lun M, Maynard T, Gonzalez D, Kim S, Ye P, D'Ercole AJ, Wong ET, LaMantia AS, Walsh CA. The cerebrospinal fluid provides a proliferative niche for neural progenitor cells. Neuron. 69: 893-905. PMID 21382550 DOI: 10.1016/J.Neuron.2011.01.023 |
0.682 |
|
2010 |
Tucker ES, Lehtinen MK, Maynard T, Zirlinger M, Dulac C, Rawson N, Pevny L, Lamantia AS. Proliferative and transcriptional identity of distinct classes of neural precursors in the mammalian olfactory epithelium. Development (Cambridge, England). 137: 2471-81. PMID 20573694 DOI: 10.1242/Dev.049718 |
0.324 |
|
2010 |
Kim S, Lehtinen MK, Sessa A, Zappaterra MW, Cho SH, Gonzalez D, Boggan B, Austin CA, Wijnholds J, Gambello MJ, Malicki J, LaMantia AS, Broccoli V, Walsh CA. The apical complex couples cell fate and cell survival to cerebral cortical development. Neuron. 66: 69-84. PMID 20399730 DOI: 10.1016/J.Neuron.2010.03.019 |
0.533 |
|
2009 |
Lehtinen MK, Tegelberg S, Schipper H, Su H, Zukor H, Manninen O, Kopra O, Joensuu T, Hakala P, Bonni A, Lehesjoki AE. Cystatin B deficiency sensitizes neurons to oxidative stress in progressive myoclonus epilepsy, EPM1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5910-5. PMID 19420257 DOI: 10.1523/Jneurosci.0682-09.2009 |
0.561 |
|
2009 |
Yuan Z, Lehtinen MK, Merlo P, Villén J, Gygi S, Bonni A. Regulation of neuronal cell death by MST1-FOXO1 signaling. The Journal of Biological Chemistry. 284: 11285-92. PMID 19221179 DOI: 10.1074/Jbc.M900461200 |
0.609 |
|
2008 |
Lehtinen MK, Bonni A. Demystifying MST family kinases in cell death. Current Molecular Medicine. 8: 313-8. PMID 18537638 DOI: 10.2174/156652408784533805 |
0.599 |
|
2006 |
Lehtinen MK, Bonni A. Modeling oxidative stress in the central nervous system. Current Molecular Medicine. 6: 871-81. PMID 17168738 DOI: 10.2174/156652406779010786 |
0.575 |
|
2006 |
Lehtinen MK, Yuan Z, Boag PR, Yang Y, Villén J, Becker EB, DiBacco S, de la Iglesia N, Gygi S, Blackwell TK, Bonni A. A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell. 125: 987-1001. PMID 16751106 DOI: 10.1016/J.Cell.2006.03.046 |
0.742 |
|
2005 |
Benedito AB, Lehtinen M, Massol R, Lopes UG, Kirchhausen T, Rao A, Bonni A. The transcription factor NFAT3 mediates neuronal survival. The Journal of Biological Chemistry. 280: 2818-25. PMID 15537643 DOI: 10.1074/Jbc.M408741200 |
0.596 |
|
2003 |
Shalizi A, Lehtinen M, Gaudilliere B, Donovan N, Han J, Konishi Y, Bonni A. Characterization of a neurotrophin signaling mechanism that mediates neuron survival in a temporally specific pattern. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7326-36. PMID 12917366 DOI: 10.1523/Jneurosci.23-19-07326.2003 |
0.775 |
|
2002 |
Konishi Y, Lehtinen M, Donovan N, Bonni A. Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery. Molecular Cell. 9: 1005-16. PMID 12049737 DOI: 10.1016/S1097-2765(02)00524-5 |
0.594 |
|
2001 |
Wiemelt AP, Lehtinen M, McMorris FA. Agonists calcitonin, corticotropin-releasing hormone, and vasoactive intestinal peptide, but not prostaglandins or beta-adrenergic agonists, elevate cyclic adenosine monophosphate levels in oligodendroglial cells. Journal of Neuroscience Research. 65: 165-72. PMID 11438985 DOI: 10.1002/Jnr.1139 |
0.315 |
|
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