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Ohannes K. Melemedjian, Ph.D. - Publications

Affiliations: 
Molecular & Cellular Biology University of Arizona, Tucson, AZ 
Area:
Pain
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21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Haque MM, Kuppusamy P, Melemedjian OK. Glutamine Oxidation in Mouse Dorsal Root Ganglia Regulates Pain Resolution and Chronification. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 39379157 DOI: 10.1523/JNEUROSCI.1442-24.2024  0.463
2024 Kuppusamy P, Haque MM, Traub RJ, Melemedjian OK. Targeting metabolic pathways alleviates bortezomib-induced neuropathic pain without compromising anticancer efficacy in a sex-specific manner. Frontiers in Pain Research (Lausanne, Switzerland). 5: 1424348. PMID 38979441 DOI: 10.3389/fpain.2024.1424348  0.367
2023 Da Silva JT, Hernandez-Rojas LG, Mekonen HK, Hanson S, Melemedjian O, Scott AJ, Ernst RK, Seminowicz DA, Traub RJ. Sex differences in visceral sensitivity and brain activity in a rat model of comorbid pain: a longitudinal study. Pain. PMID 37756658 DOI: 10.1097/j.pain.0000000000003074  0.432
2019 Ludman T, Melemedjian OK. Bortezomib and metformin opposingly regulate the expression of hypoxia-inducible factor alpha and the consequent development of chemotherapy-induced painful peripheral neuropathy. Molecular Pain. 15: 1744806919850043. PMID 31041875 DOI: 10.1177/1744806919850043  0.349
2019 Ludman T, Melemedjian OK. Bortezomib-induced aerobic glycolysis contributes to chemotherapy-induced painful peripheral neuropathy. Molecular Pain. 15: 1744806919837429. PMID 30810076 DOI: 10.1177/1744806919837429  0.376
2017 Moy JK, Khoutorsky A, Asiedu MN, Black BJ, Kuhn JL, Barragán-Iglesias P, Megat S, Burton MD, Burgos-Vega CC, Melemedjian OK, Boitano S, Vagner J, Gkogkas CG, Pancrazio JJ, Mogil JS, et al. The MNK - eIF4E signaling axis contributes to injury-induced nociceptive plasticity and the development of chronic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28674170 DOI: 10.1523/Jneurosci.0220-17.2017  0.464
2016 Auh QS, Chun YH, Melemedjian OK, Zhang Y, Ro JY. Peripheral interactions between cannabinoid and opioid receptor agonists in a model of inflammatory mechanical hyperalgesia. Brain Research Bulletin. PMID 27450703 DOI: 10.1016/j.brainresbull.2016.07.009  0.324
2015 Melemedjian OK, Khoutorsky A. Translational control of chronic pain. Progress in Molecular Biology and Translational Science. 131: 185-213. PMID 25744674 DOI: 10.1016/bs.pmbts.2014.11.006  0.412
2015 Wei X, Yan J, Tillu D, Asiedu M, Weinstein N, Melemedjian O, Price T, Dussor G. Meningeal norepinephrine produces headache behaviors in rats via actions both on dural afferents and fibroblasts. Cephalalgia : An International Journal of Headache. PMID 25601915 DOI: 10.1177/0333102414566861  0.316
2014 Melemedjian OK, Tillu DV, Moy JK, Asiedu MN, Mandell EK, Ghosh S, Dussor G, Price TJ. Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity. Molecular Pain. 10: 45. PMID 24993495 DOI: 10.1186/1744-8069-10-45  0.3
2013 Melemedjian OK, Khoutorsky A, Sorge RE, Yan J, Asiedu MN, Valdez A, Ghosh S, Dussor G, Mogil JS, Sonenberg N, Price TJ. mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK. Pain. 154: 1080-91. PMID 23607966 DOI: 10.1016/J.Pain.2013.03.021  0.432
2013 Melemedjian OK, Tillu DV, Asiedu MN, Mandell EK, Moy JK, Blute VM, Taylor CJ, Ghosh S, Price TJ. BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state. Molecular Pain. 9: 12. PMID 23510079 DOI: 10.1186/1744-8069-9-12  0.409
2012 King T, Qu C, Okun A, Melemedjian OK, Mandell EK, Maskaykina IY, Navratilova E, Dussor GO, Ghosh S, Price TJ, Porreca F. Contribution of PKMζ-dependent and independent amplification to components of experimental neuropathic pain. Pain. 153: 1263-73. PMID 22482911 DOI: 10.1016/J.Pain.2012.03.006  0.421
2012 Yan J, Melemedjian OK, Price TJ, Dussor G. Sensitization of dural afferents underlies migraine-related behavior following meningeal application of interleukin-6 (IL-6). Molecular Pain. 8: 6. PMID 22273495 DOI: 10.1186/1744-8069-8-6  0.431
2012 Tillu DV, Melemedjian OK, Asiedu MN, Qu N, De Felice M, Dussor G, Price TJ. Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain. Molecular Pain. 8: 5. PMID 22269797 DOI: 10.1186/1744-8069-8-5  0.55
2012 Price TJ, Melemedjian OK. Fragile X mental retardation protein (FMRP) and the spinal sensory system. Results and Problems in Cell Differentiation. 54: 41-59. PMID 22009347 DOI: 10.1007/978-3-642-21649-7_4  0.343
2011 Melemedjian OK, Asiedu MN, Tillu DV, Sanoja R, Yan J, Lark A, Khoutorsky A, Johnson J, Peebles KA, Lepow T, Sonenberg N, Dussor G, Price TJ. Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain. Molecular Pain. 7: 70. PMID 21936900 DOI: 10.1186/1744-8069-7-70  0.394
2011 Asiedu MN, Tillu DV, Melemedjian OK, Shy A, Sanoja R, Bodell B, Ghosh S, Porreca F, Price TJ. Spinal protein kinase M ζ underlies the maintenance mechanism of persistent nociceptive sensitization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6646-53. PMID 21543593 DOI: 10.1523/Jneurosci.6286-10.2011  0.429
2010 Melemedjian OK, Asiedu MN, Tillu DV, Peebles KA, Yan J, Ertz N, Dussor GO, Price TJ. IL-6- and NGF-induced rapid control of protein synthesis and nociceptive plasticity via convergent signaling to the eIF4F complex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15113-23. PMID 21068317 DOI: 10.1523/Jneurosci.3947-10.2010  0.419
2010 Vardanyan M, Melemedjian OK, Price TJ, Ossipov MH, Lai J, Roberts E, Boos TL, Deschamps JR, Jacobson AE, Rice KC, Porreca F. Reversal of pancreatitis-induced pain by an orally available, small molecule interleukin-6 receptor antagonist. Pain. 151: 257-65. PMID 20599324 DOI: 10.1016/J.Pain.2010.05.022  0.365
2007 King T, Vardanyan A, Majuta L, Melemedjian O, Nagle R, Cress AE, Vanderah TW, Lai J, Porreca F. Morphine treatment accelerates sarcoma-induced bone pain, bone loss, and spontaneous fracture in a murine model of bone cancer. Pain. 132: 154-68. PMID 17706870 DOI: 10.1016/J.Pain.2007.06.026  0.359
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