Year |
Citation |
Score |
2024 |
Dogrul BN, Machado Kopruszinski C, Dolatyari Eslami M, Watanabe M, Luo S, Moreira de Souza LH, Vizin RL, Yue X, Palmiter RD, Navratilova E, Porreca F. Descending facilitation from rostral ventromedial medulla mu opioid receptor-expressing neurons is necessary for maintenance of sensory and affective dimensions of chronic neuropathic pain. Pain. PMID 39058958 DOI: 10.1097/j.pain.0000000000003360 |
0.333 |
|
2023 |
Navratilova E, Qu C, Ji G, Neugebauer V, Guerrero M, Rosen H, Roberts E, Porreca F. Opposing effects on descending control of nociception by mu and kappa opioid receptors in the anterior cingulate cortex. Anesthesiology. PMID 37725756 DOI: 10.1097/ALN.0000000000004773 |
0.391 |
|
2022 |
Kopruszinski CM, Watanabe M, Martinez AL, de Souza LHM, Dodick DW, Moutal A, Neugebauer V, Porreca F, Navratilova E. Kappa opioid receptor agonists produce sexually dimorphic and prolactin-dependent hyperalgesic priming. Pain. PMID 36625833 DOI: 10.1097/j.pain.0000000000002835 |
0.425 |
|
2022 |
Kopruszinski CM, Vizin R, Watanabe M, Martinez AL, de Souza LHM, Dodick DW, Porreca F, Navratilova E. Exploring the neurobiology of the premonitory phase of migraine preclinically - a role for hypothalamic kappa opioid receptors? The Journal of Headache and Pain. 23: 126. PMID 36175828 DOI: 10.1186/s10194-022-01497-7 |
0.414 |
|
2022 |
Yakhnitsa V, Ji G, Hein M, Presto P, Griffin Z, Ponomareva O, Navratilova E, Porreca F, Neugebauer V. Kappa Opioid Receptor Blockade in the Amygdala Mitigates Pain Like-Behaviors by Inhibiting Corticotropin Releasing Factor Neurons in a Rat Model of Functional Pain. Frontiers in Pharmacology. 13: 903978. PMID 35694266 DOI: 10.3389/fphar.2022.903978 |
0.373 |
|
2022 |
Sato D, Narita M, Hamada Y, Mori T, Tanaka K, Tamura H, Yamanaka A, Matsui R, Watanabe D, Suda Y, Senba E, Watanabe M, Navratilova E, Porreca F, Kuzumaki N, et al. Relief of neuropathic pain by cell-specific manipulation of nucleus accumbens dopamine D1- and D2-receptor-expressing neurons. Molecular Brain. 15: 10. PMID 34991655 DOI: 10.1186/s13041-021-00896-2 |
0.309 |
|
2021 |
Hein M, Ji G, Tidwell D, D'Souza P, Kiritoshi T, Yakhnitsa V, Navratilova E, Porreca F, Neugebauer V. Kappa opioid receptor activation in the amygdala disinhibits CRF neurons to generate pain-like behaviors. Neuropharmacology. 185: 108456. PMID 33444637 DOI: 10.1016/j.neuropharm.2021.108456 |
0.318 |
|
2020 |
Kopruszinski CM, Thornton P, Arnold J, Newton P, Lowne D, Navratilova E, Swiokla J, Dodick DW, Dobson C, Gurrell I, Chessell IP, Porreca F. Characterization and preclinical evaluation of a protease activated receptor 2 (PAR2) monoclonal antibody as a preventive therapy for migraine. Cephalalgia : An International Journal of Headache. 333102420966581. PMID 33131305 DOI: 10.1177/0333102420966581 |
0.305 |
|
2020 |
Chen Y, Navratilova E, Dodick DW, Porreca F. An Emerging Role for Prolactin in Female-Selective Pain. Trends in Neurosciences. PMID 32620290 DOI: 10.1016/J.Tins.2020.06.003 |
0.386 |
|
2020 |
Navratilova E, Behravesh S, Oyarzo J, Dodick DW, Banerjee P, Porreca F. Ubrogepant does not induce latent sensitization in a preclinical model of medication overuse headache. Cephalalgia : An International Journal of Headache. 333102420938652. PMID 32615788 DOI: 10.1177/0333102420938652 |
0.375 |
|
2020 |
Gee TA, Weintraub NC, Lu D, Phelps CE, Navratilova E, Heien ML, Porreca F. A pain-induced tonic hypodopaminergic state augments phasic dopamine release in the nucleus accumbens. Pain. PMID 32453137 DOI: 10.1097/J.Pain.0000000000001925 |
0.312 |
|
2020 |
Neugebauer V, Mazzitelli M, Cragg B, Ji G, Navratilova E, Porreca F. Amygdala, neuropeptides, and chronic pain-related affective behaviors. Neuropharmacology. 108052. PMID 32188569 DOI: 10.1016/J.Neuropharm.2020.108052 |
0.426 |
|
2020 |
Chen Y, Moutal A, Navratilova E, Kopruszinski C, Yue X, Ikegami M, Chow M, Kanazawa I, Bellampalli SS, Xie J, Patwardhan A, Rice K, Fields H, Akopian A, Neugebauer V, et al. Erratum: The prolactin receptor long isoform regulates nociceptor sensitization and opioid-induced hyperalgesia selectively in females (Science Translational Medicine DOI: 10.1126/scitranslmed.aay7550) Science Translational Medicine. 12. PMID 32132219 DOI: 10.1126/Scitranslmed.Abb4549 |
0.55 |
|
2020 |
Kopruszinski CM, Swiokla J, Lee YS, Navratilova E, VanderVeen L, Yang M, Liu Y, Miyazaki T, Schmidt WK, Zalevsky J, Porreca F. Preclinical Assessment of the Analgesic Pharmacology of NKTR-181 in Rodents. Cellular and Molecular Neurobiology. PMID 32107752 DOI: 10.1007/S10571-020-00816-3 |
0.61 |
|
2020 |
Chen Y, Moutal A, Navratilova E, Kopruszinski C, Yue X, Ikegami M, Chow M, Kanazawa I, Bellampalli SS, Xie J, Patwardhan A, Rice K, Fields H, Akopian A, Neugebauer V, et al. The prolactin receptor long isoform regulates nociceptor sensitization and opioid-induced hyperalgesia selectively in females. Science Translational Medicine. 12. PMID 32024801 DOI: 10.1126/Scitranslmed.Aay7550 |
0.428 |
|
2020 |
Dickenson AH, Navratilova E, Patel R, Porreca F, Bannister K. Supraspinal Opioid Circuits Differentially Modulate Spinal Neuronal Responses in Neuropathic Rats. Anesthesiology. PMID 31977518 DOI: 10.1097/Aln.0000000000003120 |
0.434 |
|
2019 |
Navratilova E, Nation K, Remeniuk B, Neugebauer V, Bannister K, Dickenson AH, Porreca F. Selective modulation of tonic aversive qualities of neuropathic pain by morphine in the central nucleus of the amygdala requires endogenous opioid signaling in the anterior cingulate cortex. Pain. PMID 31725062 DOI: 10.1097/J.Pain.0000000000001748 |
0.556 |
|
2019 |
Kopruszinski CM, Navratilova E, Vagnerova B, Swiokla J, Patwardhan A, Dodick D, Porreca F. Cannabinoids induce latent sensitization in a preclinical model of medication overuse headache. Cephalalgia : An International Journal of Headache. 333102419865252. PMID 31311288 DOI: 10.1177/0333102419865252 |
0.346 |
|
2019 |
Navratilova E, Patwardhan A, Porreca F. Opioid analgesics pass the acid test. Lancet (London, England). 393: 1579-1581. PMID 31007186 DOI: 10.1016/S0140-6736(19)30421-0 |
0.502 |
|
2019 |
Phelps CE, Navratilova E, Dickenson AH, Porreca F, Bannister K. Kappa Opioid Signaling in the Right Central Amygdala Causes Hindpaw Specific Loss of Diffuse Noxious Inhibitory Controls (DNIC) in Experimental Neuropathic Pain. Pain. PMID 30870321 DOI: 10.1097/J.Pain.0000000000001553 |
0.452 |
|
2019 |
Navratilova E, Porreca F. Substance P and Inflammatory Pain: Getting It Wrong and Right Simultaneously. Neuron. 101: 353-355. PMID 30731054 DOI: 10.1016/J.Neuron.2019.01.034 |
0.328 |
|
2018 |
Navratilova E, Ji G, Phelps C, Qu C, Hein M, Yakhnitsa V, Neugebauer V, Porreca F. Kappa opioid signaling in the central nucleus of the amygdala promotes disinhibition and aversiveness of chronic neuropathic pain. Pain. PMID 30681985 DOI: 10.1097/J.Pain.0000000000001458 |
0.471 |
|
2018 |
Nation KM, Dodick DW, Navratilova E, Porreca F. Sustained exposure to acute migraine medications combined with repeated noxious stimulation dysregulates descending pain modulatory circuits: Relevance to medication overuse headache. Cephalalgia : An International Journal of Headache. 333102418804157. PMID 30286616 DOI: 10.1177/0333102418804157 |
0.376 |
|
2018 |
Becker S, Navratilova E, Nees F, Van Damme S. Emotional and Motivational Pain Processing: Current State of Knowledge and Perspectives in Translational Research. Pain Research & Management. 2018: 5457870. PMID 30123398 DOI: 10.1155/2018/5457870 |
0.332 |
|
2018 |
Gomtsian L, Bannister K, Eyde N, Robles D, Dickenson AH, Porreca F, Navratilova E. Morphine effects within the rodent anterior cingulate cortex and rostral ventromedial medulla reveal separable modulation of affective and sensory qualities of acute or chronic pain. Pain. PMID 30086115 DOI: 10.1097/J.Pain.0000000000001355 |
0.555 |
|
2018 |
Nation KM, DeFelice M, Hernandez PI, Dodick DW, Neugebauer V, Navratilova E, Porreca F. Lateralized Kappa Opioid Receptor Signaling from the Amygdala Central Nucleus Promotes Stress-Induced Functional Pain. Pain. PMID 29369967 DOI: 10.1097/J.Pain.0000000000001167 |
0.469 |
|
2018 |
Watanabe M, Narita M, Hamada Y, Yamashita A, Tamura H, Ikegami D, Kondo T, Shinzato T, Shimizu T, Fukuchi Y, Muto A, Okano H, Yamanaka A, Tawfik V, Kuzumaki N, ... Navratilova E, et al. [EXPRESS] Activation of ventral tegmental area dopaminergic neurons reverses pathological allodynia resulting from nerve injury or bone cancer. Molecular Pain. 1744806918756406. PMID 29357732 DOI: 10.1177/1744806918756406 |
0.306 |
|
2017 |
Bannister K, Qu C, Navratilova E, Oyarzo J, Xie JY, King T, Dickenson AH, Porreca F. Multiple sites and actions of gabapentin-induced relief of ongoing experimental neuropathic pain. Pain. PMID 28832395 DOI: 10.1097/J.Pain.0000000000001040 |
0.444 |
|
2017 |
Xie JY, De Felice M, Kopruszinski CM, Eyde N, LaVigne J, Remeniuk B, Hernandez P, Yue X, Goshima N, Ossipov M, King T, Streicher JM, Navratilova E, Dodick D, Rosen H, et al. Kappa opioid receptor antagonists: A possible new class of therapeutics for migraine prevention. Cephalalgia : An International Journal of Headache. 333102417702120. PMID 28376659 DOI: 10.1177/0333102417702120 |
0.45 |
|
2017 |
Porreca F, Navratilova E. Reward, motivation and emotion of pain and its relief. Pain. PMID 28106670 DOI: 10.1097/J.Pain.0000000000000798 |
0.335 |
|
2016 |
Okun A, McKinzie DL, Witkin JM, Remeniuk B, Husein O, Gleason SD, Oyarzo J, Navratilova E, McElroy B, Cowen S, Kennedy JD, Porreca F. Hedonic and motivational responses to food reward are unchanged in rats with neuropathic pain. Pain. PMID 27548047 DOI: 10.1097/J.Pain.0000000000000695 |
0.323 |
|
2016 |
Navratilova E, Morimura K, Xie JY, Atcherley CW, Ossipov MH, Porreca F. Positive emotions and brain reward circuits in chronic pain. The Journal of Comparative Neurology. PMID 26788716 DOI: 10.1002/Cne.23968 |
0.319 |
|
2015 |
Navratilova E, Atcherley CW, Porreca F. Brain Circuits Encoding Reward from Pain Relief. Trends in Neurosciences. PMID 26603560 DOI: 10.1016/J.Tins.2015.09.003 |
0.353 |
|
2015 |
Nair P, Yamamoto T, Cowell S, Kulkarni V, Moye S, Navratilova E, Davis P, Ma SW, Vanderah TW, Lai J, Porreca F, Hruby VJ. Discovery of tripeptide-derived multifunctional ligands possessing delta/mu opioid receptor agonist and neurokinin 1 receptor antagonist activities. Bioorganic & Medicinal Chemistry Letters. 25: 3716-20. PMID 26212775 DOI: 10.1016/J.Bmcl.2015.06.030 |
0.783 |
|
2015 |
Remeniuk B, Sukhtankar D, Okun A, Navratilova E, Xie JY, King T, Porreca F. Behavioral and Neurochemical Analysis of Ongoing Bone Cancer Pain in Rats. Pain. PMID 25955964 DOI: 10.1097/J.Pain.0000000000000218 |
0.437 |
|
2015 |
Navratilova E, Xie JY, Meske D, Qu C, Morimura K, Okun A, Arakawa N, Ossipov M, Fields HL, Porreca F. Endogenous opioid activity in the anterior cingulate cortex is required for relief of pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 7264-71. PMID 25948274 DOI: 10.1523/Jneurosci.3862-14.2015 |
0.559 |
|
2014 |
Navratilova E, Porreca F. Reward and motivation in pain and pain relief. Nature Neuroscience. 17: 1304-12. PMID 25254980 DOI: 10.1038/Nn.3811 |
0.337 |
|
2014 |
Xie JY, Qu C, Patwardhan A, Ossipov MH, Navratilova E, Becerra L, Borsook D, Porreca F. Activation of mesocorticolimbic reward circuits for assessment of relief of ongoing pain: a potential biomarker of efficacy. Pain. 155: 1659-66. PMID 24861580 DOI: 10.1016/J.Pain.2014.05.018 |
0.342 |
|
2013 |
Nair P, Yamamoto T, Largent-Milnes TM, Cowell S, Kulkarni V, Moye S, Navratilova E, Davis P, Ma SW, Vanderah TW, Lai J, Porreca F, Hruby VJ. Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activities. Bioorganic & Medicinal Chemistry Letters. 23: 4975-8. PMID 23899615 DOI: 10.1016/J.Bmcl.2013.06.065 |
0.782 |
|
2013 |
Becerra L, Navratilova E, Porreca F, Borsook D. Analogous responses in the nucleus accumbens and cingulate cortex to pain onset (aversion) and offset (relief) in rats and humans. Journal of Neurophysiology. 110: 1221-6. PMID 23785130 DOI: 10.1152/Jn.00284.2013 |
0.339 |
|
2013 |
Navratilova E, Xie JY, King T, Porreca F. Evaluation of reward from pain relief. Annals of the New York Academy of Sciences. 1282: 1-11. PMID 23496247 DOI: 10.1111/Nyas.12095 |
0.327 |
|
2012 |
Navratilova E, Xie JY, Okun A, Qu C, Eyde N, Ci S, Ossipov MH, King T, Fields HL, Porreca F. Pain relief produces negative reinforcement through activation of mesolimbic reward-valuation circuitry. Proceedings of the National Academy of Sciences of the United States of America. 109: 20709-13. PMID 23184995 DOI: 10.1073/Pnas.1214605109 |
0.345 |
|
2012 |
King T, Qu C, Okun A, Melemedjian OK, Mandell EK, Maskaykina IY, Navratilova E, Dussor GO, Ghosh S, Price TJ, Porreca F. Contribution of PKMζ-dependent and independent amplification to components of experimental neuropathic pain. Pain. 153: 1263-73. PMID 22482911 DOI: 10.1016/J.Pain.2012.03.006 |
0.386 |
|
2010 |
Yamamoto T, Nair P, Jacobsen NE, Kulkarni V, Davis P, Ma SW, Navratilova E, Yamamura HI, Vanderah TW, Porreca F, Lai J, Hruby VJ. Biological and conformational evaluation of bifunctional compounds for opioid receptor agonists and neurokinin 1 receptor antagonists possessing two penicillamines. Journal of Medicinal Chemistry. 53: 5491-501. PMID 20617791 DOI: 10.1021/Jm100157M |
0.815 |
|
2009 |
Yamamoto T, Nair P, Jacobsen NE, Vagner J, Kulkarni V, Davis P, Ma SW, Navratilova E, Yamamura HI, Vanderah TW, Porreca F, Lai J, Hruby VJ. Improving metabolic stability by glycosylation: bifunctional peptide derivatives that are opioid receptor agonists and neurokinin 1 receptor antagonists. Journal of Medicinal Chemistry. 52: 5164-75. PMID 20560643 DOI: 10.1021/Jm900473P |
0.777 |
|
2009 |
Salamon Z, Fitch J, Cai M, Tumati S, Navratilova E, Tollin G. Plasmon-waveguide resonance studies of ligand binding to integral proteins in membrane fragments derived from bacterial and mammalian cells. Analytical Biochemistry. 387: 95-101. PMID 19454250 DOI: 10.1016/J.Ab.2009.01.019 |
0.495 |
|
2009 |
Nair P, Yamamoto T, Kulkarni V, Moye S, Navratilova E, Davis P, Largent T, Ma SW, Yamamura HI, Vanderah T, Lai J, Porreca F, Hruby VJ. Novel bifunctional peptides as opioid agonists and NK-1 antagonists. Advances in Experimental Medicine and Biology. 611: 537-8. PMID 19400302 DOI: 10.1007/978-0-387-73657-0_235 |
0.821 |
|
2008 |
Yamamoto T, Nair P, Jacobsen NE, Davis P, Ma SW, Navratilova E, Moye S, Lai J, Yamamura HI, Vanderah TW, Porreca F, Hruby VJ. The importance of micelle-bound states for the bioactivities of bifunctional peptide derivatives for delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists. Journal of Medicinal Chemistry. 51: 6334-47. PMID 18821747 DOI: 10.1021/Jm800389V |
0.786 |
|
2008 |
Yue X, Tumati S, Navratilova E, Strop D, St John PA, Vanderah TW, Roeske WR, Yamamura HI, Varga EV. Sustained morphine treatment augments basal CGRP release from cultured primary sensory neurons in a Raf-1 dependent manner. European Journal of Pharmacology. 584: 272-7. PMID 18328477 DOI: 10.1016/J.Ejphar.2008.02.013 |
0.703 |
|
2008 |
Yamamoto T, Nair P, Vagner J, Largent-Milnes T, Davis P, Ma SW, Navratilova E, Moye S, Tumati S, Lai J, Yamamura HI, Vanderah TW, Porreca F, Hruby VJ. A structure-activity relationship study and combinatorial synthetic approach of C-terminal modified bifunctional peptides that are delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists. Journal of Medicinal Chemistry. 51: 1369-76. PMID 18266313 DOI: 10.1021/Jm070332F |
0.8 |
|
2007 |
Yamamoto T, Nair P, Davis P, Ma SW, Navratilova E, Moye S, Tumati S, Lai J, Vanderah TW, Yamamura HI, Porreca F, Hruby VJ. Design, synthesis, and biological evaluation of novel bifunctional C-terminal-modified peptides for delta/mu opioid receptor agonists and neurokinin-1 receptor antagonists. Journal of Medicinal Chemistry. 50: 2779-86. PMID 17516639 DOI: 10.1021/Jm061369N |
0.82 |
|
2007 |
Navratilova E, Waite S, Stropova D, Eaton MC, Alves ID, Hruby VJ, Roeske WR, Yamamura HI, Varga EV. Quantitative evaluation of human delta opioid receptor desensitization using the operational model of drug action. Molecular Pharmacology. 71: 1416-26. PMID 17322005 DOI: 10.1124/Mol.106.030023 |
0.687 |
|
2005 |
Navratilova E, Eaton MC, Stropova D, Varga EV, Vanderah TW, Roeske WR, Yamamura HI. Morphine promotes phosphorylation of the human delta-opioid receptor at serine 363. European Journal of Pharmacology. 519: 212-4. PMID 16135360 DOI: 10.1016/J.Ejphar.2005.07.024 |
0.759 |
|
2005 |
Varga EV, Hosohata K, Borys D, Navratilova E, Nylen A, Vanderah TW, Porreca F, Roeske WR, Yamamura HI. Antinociception depends on the presence of G protein gamma2-subunits in brain. European Journal of Pharmacology. 508: 93-8. PMID 15680258 DOI: 10.1016/J.Ejphar.2004.11.062 |
0.69 |
|
2005 |
Gu X, Ying J, Min B, Cain JP, Davis P, Willey P, Navratilova E, Yamamura HI, Porreca F, Hruby VJ. Parallel synthesis and biological evaluation of different sizes of bicyclo[2,3]-Leu-enkephalin analogues. Biopolymers. 80: 151-63. PMID 15660379 DOI: 10.1002/Bip.20208 |
0.501 |
|
2004 |
Varga EV, Navratilova E, Stropova D, Jambrosic J, Roeske WR, Yamamura HI. Agonist-specific regulation of the delta-opioid receptor. Life Sciences. 76: 599-612. PMID 15567186 DOI: 10.1016/J.Lfs.2004.07.020 |
0.726 |
|
2004 |
Gu X, Ying J, Agnes RS, Navratilova E, Davis P, Stahl G, Porreca F, Yamamura HI, Hruby VJ. Novel design of bicyclic beta-turn dipeptides on solid-phase supports and synthesis of [3.3.0]-Bicyclo([2,3])-leu-enkephalin analogues. Organic Letters. 6: 3285-8. PMID 15355033 DOI: 10.1021/Ol0488183 |
0.556 |
|
2004 |
Elmagbari NO, Egleton RD, Palian MM, Lowery JJ, Schmid WR, Davis P, Navratilova E, Dhanasekaran M, Keyari CM, Yamamura HI, Porreca F, Hruby VJ, Polt R, Bilsky EJ. Antinociceptive structure-activity studies with enkephalin-based opioid glycopeptides. The Journal of Pharmacology and Experimental Therapeutics. 311: 290-7. PMID 15166257 DOI: 10.1124/Jpet.104.069393 |
0.655 |
|
2004 |
Navratilova E, Varga EV, Stropova D, Jambrosic JC, Roeske WR, Yamamura HI. Mutation S363A in the human delta-opioid receptor selectively reduces down-regulation by a peptide agonist. European Journal of Pharmacology. 485: 341-3. PMID 14757159 DOI: 10.1016/J.Ejphar.2003.11.067 |
0.699 |
|
2004 |
Tóth G, Keresztes A, Tömböly C, Péter A, Fülöp F, Tourwé D, Navratilova E, Varga É, Roeske WR, Yamamura HI, Szucs M, Borsodi A. New endomorphin analogs with mu-agonist and delta-antagonist properties Pure and Applied Chemistry. 76: 951-957. DOI: 10.1351/Pac200476050951 |
0.719 |
|
2004 |
Tóth G, Keresztes A, Tömböly C, Péter A, Fülöp F, Tourwé D, Navratilova E, Varga E, Roeske WR, Yamamura HI, Szucs M, Borsodi A. New endomorphin analogs with μ-agonist and δ-antagonist properties Pure and Applied Chemistry. 76: 951-957. |
0.539 |
|
2003 |
Varga EV, Yamamura HI, Rubenzik MK, Stropova D, Navratilova E, Roeske WR. Molecular mechanisms of excitatory signaling upon chronic opioid agonist treatment. Life Sciences. 74: 299-311. PMID 14607258 DOI: 10.1016/J.Lfs.2003.09.017 |
0.808 |
|
2003 |
Okura T, Varga EV, Hosohata Y, Navratilova E, Cowell SM, Rice K, Nagase H, Hruby VJ, Roeske WR, Yamamura HI. Agonist-specific down-regulation of the human delta-opioid receptor. European Journal of Pharmacology. 459: 9-16. PMID 12505529 DOI: 10.1016/S0014-2999(02)02823-6 |
0.724 |
|
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