Yong Xu, M.D., Ph.D. - Publications

Affiliations: 
Pediatrics-Nutrition Baylor College of Medicine, Houston, TX 

135 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Yu M, Yin N, Feng B, Gao P, Yu K, Liu H, Liu H, Li Y, Ginnard OZ, Conde KM, Wang M, Fang X, Tu L, Bean JC, Liu Q, ... ... Xu Y, et al. Identification of an ionic mechanism for ERα-mediated rapid excitation in neurons. Science Advances. 10: eadp0696. PMID 39356770 DOI: 10.1126/sciadv.adp0696  0.724
2024 Wang M, Czernik PJ, Lecka-Czernik B, Xu Y, Hill JW. IGF-1 and insulin receptors in LepRb neurons jointly regulate body growth, bone mass, reproduction, and metabolism. Biorxiv : the Preprint Server For Biology. PMID 39345425 DOI: 10.1101/2024.09.20.614140  0.641
2024 Liu H, Bean JC, Li Y, Yu M, Ginnard OZ, Conde KM, Wang M, Fang X, Liu H, Tu L, Yin N, Han J, Yang Y, Tong Q, Arenkiel BR, ... ... Xu Y, et al. Distinct basal forebrain-originated neural circuits promote homoeostatic feeding and suppress hedonic feeding in male mice. Nature Metabolism. PMID 39112722 DOI: 10.1038/s42255-024-01099-4  0.621
2024 Wang M, Pugh SM, Daboul J, Miller D, Xu Y, Hill JW. IGF-1 Acts through Kiss1-expressing Cells to Influence Metabolism and Reproduction. Biorxiv : the Preprint Server For Biology. PMID 39005405 DOI: 10.1101/2024.07.02.601722  0.448
2024 Li Y, Cacciottolo TM, Yin N, He Y, Liu H, Liu H, Yang Y, Henning E, Keogh JM, Lawler K, Mendes de Oliveira E, Gardner EJ, Kentistou KA, Laouris P, Bounds R, ... ... Xu Y, et al. Loss of transient receptor potential channel 5 causes obesity and postpartum depression. Cell. PMID 38959890 DOI: 10.1016/j.cell.2024.06.001  0.577
2024 Liu H, He Y, Liu H, Brouwers B, Yin N, Lawler K, Keogh JM, Henning E, Lee DK, Yu M, Tu L, Zhang N, Conde KM, Han J, Yan Z, ... ... Xu Y, et al. Neural circuits expressing the serotonin 2C receptor regulate memory in mice and humans. Science Advances. 10: eadl2675. PMID 38941473 DOI: 10.1126/sciadv.adl2675  0.612
2024 Liu H, Qu N, Gonzalez NV, Palma MA, Chen H, Xiong J, Choubey A, Li Y, Li X, Yu M, Liu H, Tu L, Zhang N, Yin N, Conde KM, ... ... Xu Y, et al. A light-responsive neural circuit suppresses feeding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 38897723 DOI: 10.1523/JNEUROSCI.2192-23.2024  0.585
2024 Conde KM, Wong H, Fang S, Li Y, Yu M, Deng Y, Liu Q, Fang X, Wang M, Shi Y, Ginnard OZ, Yang Y, Tu L, Liu H, Liu H, ... ... Xu Y, et al. 5-HT Neurons Integrate GABA and Dopamine Inputs to Regulate Meal Initiation. Biorxiv : the Preprint Server For Biology. PMID 38746314 DOI: 10.1101/2024.04.26.591360  0.609
2023 Cai J, Jiang Y, Xu Y, Jiang Z, Young C, Li H, Ortiz-Guzman J, Zhuo Y, Li Y, Xu Y, Arenkiel BR, Tong Q. An excitatory projection from the basal forebrain to the ventral tegmental area that underlies anorexia-like phenotypes. Neuron. PMID 38056455 DOI: 10.1016/j.neuron.2023.11.001  0.342
2023 Tu L, He Y, Xu Y. Anoctamin 4 defines glucose-inhibited neurons in the ventromedial hypothalamus. Neural Regeneration Research. 19: 1177-1178. PMID 37905852 DOI: 10.4103/1673-5374.385867  0.664
2023 Tu L, Bean JC, He Y, Liu H, Yu M, Liu H, Zhang N, Yin N, Han J, Scarcelli NA, Conde KM, Wang M, Li Y, Feng B, Gao P, ... ... Xu Y, et al. Anoctamin 4 channel currents activate glucose-inhibited neurons in the mouse ventromedial hypothalamus during hypoglycemia. The Journal of Clinical Investigation. PMID 37261917 DOI: 10.1172/JCI163391  0.761
2023 Xu Y, Jiang Z, Li H, Cai J, Jiang Y, Otiz-Guzman J, Xu Y, Arenkiel BR, Tong Q. Lateral septum as a melanocortin downstream site in obesity development. Cell Reports. 42: 112502. PMID 37171957 DOI: 10.1016/j.celrep.2023.112502  0.394
2023 Li H, Xu Y, Jiang Y, Jiang Z, Otiz-Guzman J, Morrill JC, Cai J, Mao Z, Xu Y, Arenkiel BR, Huang C, Tong Q. The melanocortin action is biased toward protection from weight loss in mice. Nature Communications. 14: 2200. PMID 37069175 DOI: 10.1038/s41467-023-37912-z  0.318
2023 Han Y, He Y, Harris L, Xu Y, Wu Q. Identification of a GABAergic neural circuit governing leptin signaling deficiency-induced obesity. Elife. 12. PMID 37043384 DOI: 10.7554/eLife.82649  0.416
2023 Liu H, He Y, Bai J, Zhang C, Zhang F, Yang Y, Luo H, Yu M, Liu H, Tu L, Zhang N, Yin N, Han J, Yan Z, Scarcelli NA, ... ... Xu Y, et al. Hypothalamic Grb10 enhances leptin signalling and promotes weight loss. Nature Metabolism. PMID 36593271 DOI: 10.1038/s42255-022-00701-x  0.693
2022 He Y, Brouwers B, Liu H, Liu H, Lawler K, Mendes de Oliveira E, Lee DK, Yang Y, Cox AR, Keogh JM, Henning E, Bounds R, Perdikari A, Ayinampudi V, Wang C, ... ... Xu Y, et al. Human loss-of-function variants in the serotonin 2C receptor associated with obesity and maladaptive behavior. Nature Medicine. PMID 36536256 DOI: 10.1038/s41591-022-02106-5  0.566
2022 Yu M, Bean JC, Liu H, He Y, Yang Y, Cai X, Yu K, Pei Z, Liu H, Tu L, Conde KM, Wang M, Li Y, Yin N, Zhang N, ... ... Xu Y, et al. SK3 in POMC neurons plays a sexually dimorphic role in energy and glucose homeostasis. Cell & Bioscience. 12: 170. PMID 36210455 DOI: 10.1186/s13578-022-00907-2  0.777
2022 Pei Z, He Y, Bean JC, Yang Y, Liu H, Yu M, Yu K, Hyseni I, Cai X, Liu H, Qu N, Tu L, Conde KM, Wang M, Li Y, ... ... Xu Y, et al. Gabra5 plays a sexually dimorphic role in POMC neuron activity and glucose balance. Frontiers in Endocrinology. 13: 889122. PMID 36120438 DOI: 10.3389/fendo.2022.889122  0.808
2022 Cai X, Liu H, Feng B, Yu M, He Y, Liu H, Liang C, Yang Y, Tu L, Zhang N, Wang L, Yin N, Han J, Yan Z, Wang C, ... ... Xu Y, et al. Publisher Correction: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice. Nature Neuroscience. PMID 35729403 DOI: 10.1038/s41593-022-01116-3  0.697
2022 Liu H, Cai X, He Y, Xu Y. Hyperactivity of a midbrain dopamine to 5-HT circuit causes anorexia. Journal of Molecular Cell Biology. PMID 35612989 DOI: 10.1093/jmcb/mjac035  0.534
2022 Cai X, Liu H, Feng B, Yu M, He Y, Liu H, Liang C, Yang Y, Tu L, Zhang N, Wang L, Yin N, Han J, Yan Z, Wang C, ... ... Xu Y, et al. A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice. Nature Neuroscience. 25: 646-658. PMID 35501380 DOI: 10.1038/s41593-022-01062-0  0.737
2022 Mishra I, Xie WR, Bournat JC, He Y, Wang C, Silva ES, Liu H, Ku Z, Chen Y, Erokwu BO, Jia P, Zhao Z, An Z, Flask CA, He Y, ... Xu Y, et al. Protein tyrosine phosphatase receptor δ serves as the orexigenic asprosin receptor. Cell Metabolism. PMID 35298903 DOI: 10.1016/j.cmet.2022.02.012  0.647
2022 Ye H, Feng B, Wang C, Saito K, Yang Y, Ibrahimi L, Schaul S, Patel N, Saenz L, Luo P, Lai P, Torres V, Kota M, Dixit D, Cai X, ... ... Xu Y, et al. An estrogen-sensitive hypothalamus-midbrain neural circuit controls thermogenesis and physical activity. Science Advances. 8: eabk0185. PMID 35044814 DOI: 10.1126/sciadv.abk0185  0.794
2021 Yang Y, He Y, Liu H, Zhou W, Wang C, Xu P, Cai X, Liu H, Yu K, Pei Z, Hyseni I, Fukuda M, Tong Q, Xu J, Sun Z, ... ... Xu Y, et al. Hypothalamic steroid receptor coactivator-2 regulates adaptations to fasting and overnutrition. Cell Reports. 37: 110075. PMID 34879284 DOI: 10.1016/j.celrep.2021.110075  0.743
2021 Yoo ES, Li L, Jia L, Lord CC, Lee CE, Birnbaum SG, Vianna CR, Berglund ED, Cunningham KA, Xu Y, Sohn JW, Liu C. Gα-coupled Htr2c in the paraventricular nucleus of the hypothalamus antagonizes the anorectic effect of serotonin agents. Cell Reports. 37: 109997. PMID 34788630 DOI: 10.1016/j.celrep.2021.109997  0.693
2021 Tu L, Zhang N, Conde KM, Bean JC, Wang C, Xu Y. Free-floating Immunostaining of Mouse Brains. Journal of Visualized Experiments : Jove. PMID 34694284 DOI: 10.3791/62876  0.451
2021 Yan Z, He Y, Cai X, Shu G, Xu Y. Eating for hunger or pleasure: a Serotonin Model. Journal of Molecular Cell Biology. PMID 34480567 DOI: 10.1093/jmcb/mjab055  0.535
2021 Zhang N, Yan Z, Liu H, Yu M, He Y, Liu H, Liang C, Tu L, Wang L, Yin N, Han J, Scarcelli N, Yang Y, Wang C, Zeng T, ... ... Xu Y, et al. Hypothalamic Perineuronal Nets Are Regulated by Sex and Dietary Interventions. Frontiers in Physiology. 12: 714104. PMID 34393830 DOI: 10.3389/fphys.2021.714104  0.302
2021 He Y, Cai X, Liu H, Conde KM, Xu P, Li Y, Wang C, Yu M, He Y, Liu H, Liang C, Yang T, Yang Y, Yu K, Wang J, ... ... Xu Y, et al. 5-HT recruits distinct neurocircuits to inhibit hunger-driven and non-hunger-driven feeding. Molecular Psychiatry. PMID 34290371 DOI: 10.1038/s41380-021-01220-z  0.769
2021 Ding G, Li X, Hou X, Zhou W, Gong Y, Liu F, He Y, Song J, Wang J, Basil P, Li W, Qian S, Saha P, Wang J, Cui C, ... ... Xu Y, et al. Author Correction: REV-ERB in GABAergic neurons controls diurnal hepatic insulin sensitivity. Nature. 595: E2. PMID 34131305 DOI: 10.1038/s41586-021-03654-5  0.625
2021 Han Y, Xia G, Srisai D, Meng F, He Y, Ran Y, He Y, Farias M, Hoang G, Tóth I, Dietrich MO, Chen MH, Xu Y, Wu Q. Deciphering an AgRP-serotoninergic neural circuit in distinct control of energy metabolism from feeding. Nature Communications. 12: 3525. PMID 34112797 DOI: 10.1038/s41467-021-23846-x  0.701
2021 Han Y, Xia G, He Y, He Y, Farias M, Xu Y, Wu Q. A hindbrain dopaminergic neural circuit prevents weight gain by reinforcing food satiation. Science Advances. 7. PMID 34039606 DOI: 10.1126/sciadv.abf8719  0.675
2021 He Y, Liu H, Yin N, Yang Y, Wang C, Yu M, Liu H, Liang C, Wang J, Tu L, Zhang N, Wang L, He Y, Fukuda M, Wu Q, ... ... Xu Y, et al. Barbadin potentiates long-term effects of lorcaserin on POMC neurons and weight loss. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34031163 DOI: 10.1523/JNEUROSCI.3210-20.2021  0.64
2021 Fan S, Xu Y, Lu Y, Jiang Z, Li H, Morrill JC, Cai J, Wu Q, Xu Y, Xue M, Arenkiel BR, Huang C, Tong Q. A neural basis for brain leptin action on reducing type 1 diabetic hyperglycemia. Nature Communications. 12: 2662. PMID 33976218 DOI: 10.1038/s41467-021-22940-4  0.431
2021 Kaneko K, Lin HY, Fu Y, Saha PK, De la Puente-Gomez AB, Xu Y, Ohinata K, Chen P, Morozov A, Fukuda M. Rap1 in the VMH regulates glucose homeostasis. Jci Insight. PMID 33974562 DOI: 10.1172/jci.insight.142545  0.342
2021 Xia G, Han Y, Meng F, He Y, Srisai D, Farias M, Dang M, Palmiter RD, Xu Y, Wu Q. Reciprocal control of obesity and anxiety-depressive disorder via a GABA and serotonin neural circuit. Molecular Psychiatry. PMID 33767348 DOI: 10.1038/s41380-021-01053-w  0.663
2021 Ding G, Li X, Hou X, Zhou W, Gong Y, Liu F, He Y, Song J, Wang J, Basil P, Li W, Qian S, Saha P, Wang J, Cui C, ... ... Xu Y, et al. REV-ERB in GABAergic neurons controls diurnal hepatic insulin sensitivity. Nature. PMID 33762728 DOI: 10.1038/s41586-021-03358-w  0.661
2021 Wang C, Zhou W, He Y, Yang T, Xu P, Yang Y, Cai X, Wang J, Liu H, Yu M, Liang C, Yang T, Liu H, Fukuda M, Tong Q, ... ... Xu Y, et al. AgRP neurons trigger long-term potentiation and facilitate food seeking. Translational Psychiatry. 11: 11. PMID 33414382 DOI: 10.1038/s41398-020-01161-1  0.727
2020 Zhang Z, Reis FMCV, He Y, Park JW, DiVittorio JR, Sivakumar N, van Veen JE, Maesta-Pereira S, Shum M, Nichols I, Massa MG, Anderson S, Paul K, Liesa M, Ajijola OA, ... Xu Y, et al. Estrogen-sensitive medial preoptic area neurons coordinate torpor in mice. Nature Communications. 11: 6378. PMID 33311503 DOI: 10.1038/s41467-020-20050-1  0.691
2020 Liu H, Xu Y, Hu F. AMPK in the Ventromedial Nucleus of the Hypothalamus: A Key Regulator for Thermogenesis. Frontiers in Endocrinology. 11: 578830. PMID 33071984 DOI: 10.3389/fendo.2020.578830  0.327
2020 Liu H, Wang C, Yu M, Yang Y, He Y, Liu H, Liang C, Tu L, Zhang N, Wang L, Wang J, Liu F, Hu F, Xu Y. TPH2 in the dorsal Raphe nuclei regulates energy balance in a sex-dependent manner. Endocrinology. PMID 33034617 DOI: 10.1210/endocr/bqaa183  0.364
2020 Yang Y, Xu Y. The Central Melanocortin System and Human Obesity. Journal of Molecular Cell Biology. PMID 32976556 DOI: 10.1093/jmcb/mjaa048  0.364
2020 Kim ER, Xu Y, Cassidy RM, Lu Y, Yang Y, Tian J, Li DP, Van Drunen R, Ribas-Latre A, Cai ZL, Xue M, Arenkiel BR, Eckel-Mahan K, Xu Y, Tong Q. Paraventricular hypothalamus mediates diurnal rhythm of metabolism. Nature Communications. 11: 3794. PMID 32732906 DOI: 10.1038/S41467-020-17578-7  0.466
2020 Zhu C, Jiang Z, Xu Y, Cai ZL, Jiang Q, Xu Y, Xue M, Arenkiel BR, Wu Q, Shu G, Tong Q. Profound and redundant functions of arcuate neurons in obesity development. Nature Metabolism. PMID 32719538 DOI: 10.1038/s42255-020-0229-2  0.364
2020 Yu K, He Y, Hyseni I, Pei Z, Yang Y, Xu P, Cai X, Liu H, Qu N, Liu H, He Y, Yu M, Liang C, Yang T, Wang J, ... ... Xu Y, et al. 17β-estradiol promotes acute refeeding in hungry mice by membrane-initiated ERα signaling. Molecular Metabolism. 101053. PMID 32712433 DOI: 10.1016/J.Molmet.2020.101053  0.681
2020 Fu Y, Kaneko K, Lin HY, Mo Q, Xu Y, Suganami T, Ravn P, Fukuda M. Gut hormone GIP induces inflammation and insulin resistance in the hypothalamus. Endocrinology. PMID 32603429 DOI: 10.1210/Endocr/Bqaa102  0.374
2020 Zhu C, Xu Y, Jiang Z, Tian JB, Cassidy RM, Cai ZL, Shu G, Xu Y, Xue M, Arenkiel BR, Jiang Q, Tong Q. Disrupted hypothalamic CRH neuron responsiveness contributes to diet-induced obesity. Embo Reports. e49210. PMID 32462726 DOI: 10.15252/Embr.201949210  0.484
2020 Sun Z, Xu Y. Nuclear Receptor Coactivators (NCOAs) and Corepressors (NCORs) in the Brain. Endocrinology. PMID 32449767 DOI: 10.1210/Endocr/Bqaa083  0.342
2020 da Silva Teixeira S, Harrison K, Uzodike M, Rajapakshe K, Coarfa C, He Y, Xu Y, Sisley S. Vitamin D actions in neurons require the PI3K pathway for both enhancing insulin signaling and rapid depolarizing effects. The Journal of Steroid Biochemistry and Molecular Biology. 200: 105690. PMID 32408067 DOI: 10.1016/J.Jsbmb.2020.105690  0.629
2020 He Y, Xu P, Wang C, Xia Y, Yu M, Yang Y, Yu K, Cai X, Qu N, Saito K, Wang J, Hyseni I, Robertson M, Piyarathna B, Gao M, ... ... Xu Y, et al. Estrogen receptor-α expressing neurons in the ventrolateral VMH regulate glucose balance. Nature Communications. 11: 2165. PMID 32358493 DOI: 10.1038/S41467-020-15982-7  0.768
2020 Wooton-Kee CR, Robertson M, Zhou Y, Dong B, Sun Z, Kim KH, Liu H, Xu Y, Putluri N, Saha P, Coarfa C, Moore DD, Nuotio-Antar AM. Metabolic dysregulation in the Wilson's disease mouse model. Proceedings of the National Academy of Sciences of the United States of America. PMID 31924743 DOI: 10.1073/Pnas.1914267117  0.385
2020 He Y, Liu H, Xu Y. 140-OR: Inhibition of Serotonin 2c Receptor Internalization Potentiates Lorcaserin Effect on Body Weight Loss Diabetes. 69. DOI: 10.2337/Db20-140-Or  0.509
2019 Qu N, He Y, Wang C, Xu P, Yang Y, Cai X, Liu H, Yu K, Pei Z, Hyseni I, Sun Z, Fukuda M, Li Y, Tian Q, Xu Y. A POMC-originated circuit regulates stress-induced hypophagia, depression, and anhedonia. Molecular Psychiatry. PMID 31485012 DOI: 10.1038/S41380-019-0506-1  0.753
2019 Kaneko K, Fu Y, Lin HY, Cordonier EL, Mo Q, Gao Y, Yao T, Naylor J, Howard V, Saito K, Xu P, Chen SS, Chen MH, Xu Y, Williams KW, et al. Gut-derived GIP activates central Rap1 to impair neural leptin sensitivity during overnutrition. The Journal of Clinical Investigation. 130. PMID 31403469 DOI: 10.1172/Jci126107  0.718
2019 Xu Y, Lu Y, Cassidy RM, Mangieri LR, Zhu C, Huang X, Jiang Z, Justice NJ, Xu Y, Arenkiel BR, Tong Q. Identification of a neurocircuit underlying regulation of feeding by stress-related emotional responses. Nature Communications. 10: 3446. PMID 31371721 DOI: 10.1038/S41467-019-11399-Z  0.353
2019 Mangieri LR, Jiang Z, Lu Y, Xu Y, Cassidy RM, Justice N, Xu Y, Arenkiel BR, Tong Q. Defensive Behaviors Driven by a Hypothalamic-Ventral Midbrain Circuit. Eneuro. PMID 31331938 DOI: 10.1523/ENEURO.0156-19.2019  0.344
2019 Zhou W, He Y, Rehman AU, Kong Y, Hong S, Ding G, Yalamanchili HK, Wan YW, Paul B, Wang C, Gong Y, Zhou W, Liu H, Dean J, Scalais E, ... ... Xu Y, et al. Author Correction: Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection. Nature Neuroscience. PMID 31222187 DOI: 10.1038/S41593-019-0449-5  0.54
2019 Cordonier EL, Liu T, Saito K, Chen SS, Xu Y, Fukuda M. Luciferase Reporter Mice for Monitoring and Assessment of Hypothalamic Signaling of Expression. Journal of the Endocrine Society. 3: 1246-1260. PMID 31214662 DOI: 10.1210/Js.2019-00077  0.365
2019 Wang C, Xu Y. Mechanisms for Sex Differences in Energy Homeostasis. Journal of Molecular Endocrinology. 62: R129-R143. PMID 31130779 DOI: 10.1530/Jme-18-0165  0.342
2019 Xu Y, Nedungadi TP, Zhu L, Sobhani N, Irani BG, Davis KE, Zhang X, Zou F, Gent LM, Hahner LD, Khan SA, Elias CF, Elmquist JK, Clegg DJ. Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction. Cell Metabolism. 29: 1232. PMID 31067449 DOI: 10.1016/J.Cmet.2019.04.006  0.674
2019 Yang Y, van der Klaauw AA, Zhu L, Cacciottolo TM, He Y, Stadler LKJ, Wang C, Xu P, Saito K, Hinton A, Yan X, Keogh JM, Henning E, Banton MC, Hendricks AE, ... ... Xu Y, et al. Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis. Nature Communications. 10: 1718. PMID 30979869 DOI: 10.1038/S41467-019-08737-6  0.778
2019 Cassidy RM, Lu Y, Jere M, Tian JB, Xu Y, Mangieri LR, Felix-Okoroji B, Selever J, Xu Y, Arenkiel BR, Tong Q. A lateral hypothalamus to basal forebrain neurocircuit promotes feeding by suppressing responses to anxiogenic environmental cues. Science Advances. 5: eaav1640. PMID 30854429 DOI: 10.1126/Sciadv.Aav1640  0.391
2019 Zhou W, He Y, Rehman AU, Kong Y, Hong S, Ding G, Yalamanchili HK, Wan YW, Paul B, Wang C, Gong Y, Zhou W, Liu H, Dean J, Scalais E, ... ... Xu Y, et al. Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection. Nature Neuroscience. PMID 30664766 DOI: 10.1038/S41593-018-0311-1  0.661
2019 Xu P, He Y, Wang C, Yang Y, Cai X, Xu Y. 1796-P: A Ventral Medial Hypothalamus Estrogen Receptor a Neural Circuit Controlling Energy Expenditure Diabetes. 68. DOI: 10.2337/Db19-1796-P  0.769
2018 Yan H, Yang W, Zhou F, Li X, Pan Q, Shen Z, Han G, Newell-Fugate A, Tian Y, Majeti R, Liu W, Xu Y, Wu C, Allred K, Allred C, et al. Estrogen Improves Insulin Sensitivity and Suppresses Gluconeogenesis via the Transcription Factor Foxo1. Diabetes. PMID 30487265 DOI: 10.2337/Db18-0638  0.355
2018 Xu Y, López M. Central regulation of energy metabolism by estrogens. Molecular Metabolism. PMID 29886181 DOI: 10.1016/J.Molmet.2018.05.012  0.334
2018 Yu S, Cheng H, François M, Qualls-Creekmore E, Huesing C, He Y, Jiang Y, Gao H, Xu Y, Zsombok A, Derbenev AV, Nillni EA, Burk DH, Morrison CD, Berthoud HR, et al. Preoptic leptin signaling modulates energy balance independent of body temperature regulation. Elife. 7. PMID 29761783 DOI: 10.7554/Elife.33505  0.663
2018 Wang C, He Y, Xu P, Yang Y, Saito K, Xia Y, Yan X, Hinton A, Yan C, Ding H, Yu L, Shu G, Gupta R, Wu Q, Tong Q, ... ... Xu Y, et al. TAp63 contributes to sexual dimorphism in POMC neuron functions and energy homeostasis. Nature Communications. 9: 1544. PMID 29670083 DOI: 10.1038/S41467-018-03796-7  0.759
2018 Zhang P, Kuang H, He Y, Idiga SO, Li S, Chen Z, Yang Z, Cai X, Zhang K, Potthoff MJ, Xu Y, Lin JD. NRG1-Fc improves metabolic health via dual hepatic and central action. Jci Insight. 3. PMID 29515030 DOI: 10.1172/Jci.Insight.98522  0.664
2018 Mangieri LR, Lu Y, Xu Y, Cassidy RM, Xu Y, Arenkiel BR, Tong Q. A neural basis for antagonistic control of feeding and compulsive behaviors. Nature Communications. 9: 52. PMID 29302029 DOI: 10.1038/S41467-017-02534-9  0.383
2018 Yu S, Cheng H, François M, Qualls-Creekmore E, Huesing C, He Y, Jiang Y, Gao H, Xu Y, Zsombok A, Derbenev AV, Nillni EA, Burk DH, Morrison CD, Berthoud H, et al. Author response: Preoptic leptin signaling modulates energy balance independent of body temperature regulation Elife. DOI: 10.7554/Elife.33505.023  0.604
2018 He Y, Xu P, Xia Y, Yang Y, Cai X, Hyseni I, Xu Y. Estrogen-Responsive Neurons in the Ventrolateral VMH Regulate Glucose Balance Diabetes. 67. DOI: 10.2337/Db18-374-Or  0.776
2018 Teixeira S, He Y, Xu Y, Sisley S. Vitamin D Enhances Insulin Sensitivity in Neurons Diabetes. 67. DOI: 10.2337/Db18-278-Lb  0.619
2018 Yan H, Zhou F, Yang W, Pan Q, Shen Z, Han G, Allred K, Allred C, Xu Y, Guo S. Estrogen Improves Insulin Sensitivity and Suppresses Hepatic Glucose Production via the Transcription Factor Foxo1 Diabetes. 67. DOI: 10.2337/Db18-1875-P  0.353
2018 Wang C, He Y, Xu P, Yang Y, Xu Y. TAp63 in Mature POMC Neurons Regulates Glucose and Energy Homeostasis Diabetes. 67. DOI: 10.2337/Db18-1796-P  0.785
2017 Duerrschmid C, He Y, Wang C, Li C, Bournat JC, Romere C, Saha PK, Lee ME, Phillips KJ, Jain M, Jia P, Zhao Z, Farias M, Wu Q, Milewicz DM, ... ... Xu Y, et al. Asprosin is a centrally acting orexigenic hormone. Nature Medicine. PMID 29106398 DOI: 10.1038/Nm.4432  0.694
2017 Bai J, Cervantes C, Liu J, He S, Zhou H, Zhang B, Cai H, Yin D, Hu D, Li Z, Chen H, Gao X, Wang F, O'Connor JC, Xu Y, et al. DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mtDNA release-activated cGAS-cGAMP-STING pathway. Proceedings of the National Academy of Sciences of the United States of America. PMID 29087318 DOI: 10.1073/Pnas.1708744114  0.336
2017 Zhu C, Xu P, He Y, Yuan Y, Wang T, Cai X, Yu L, Yang L, Wu J, Wang L, Zhu X, Wang S, Gao P, Xi Q, Zhang Y, ... Xu Y, et al. Heparin Increases Food Intake through AgRP Neurons. Cell Reports. 20: 2455-2467. PMID 28877477 DOI: 10.1016/J.Celrep.2017.08.049  0.736
2017 Kim ER, Fan S, Akhmedov D, Sun K, Lim H, O'Brien W, Xu Y, Mangieri LR, Zhu Y, Lee CC, Chung Y, Xia Y, Xu Y, Li F, Sun K, et al. Red blood cell β-adrenergic receptors contribute to diet-induced energy expenditure by increasing O2 supply. Jci Insight. 2. PMID 28724789 DOI: 10.1172/Jci.Insight.93367  0.334
2017 Xu Y, Lu Y, Xu P, Mangieri LR, Isingrini E, Xu Y, Giros B, Tong Q. VMAT2-Mediated Neurotransmission from Midbrain Leptin Receptor Neurons in Feeding Regulation. Eneuro. 4. PMID 28560316 DOI: 10.1523/ENEURO.0083-17.2017  0.624
2017 Wu CS, Bongmba OYN, Yue J, Lee JH, Lin L, Saito K, Pradhan G, Li DP, Pan HL, Xu A, Guo S, Xu Y, Sun Y. Suppression of GHS-R in AgRP Neurons Mitigates Diet-Induced Obesity by Activating Thermogenesis. International Journal of Molecular Sciences. 18. PMID 28420089 DOI: 10.3390/Ijms18040832  0.494
2017 Xu P, Zhu L, Saito K, Yang Y, Wang C, He Y, Yan X, Hyseni I, Tong Q, Xu Y. Melanocortin 4 receptor is not required for estrogenic regulations on energy homeostasis and reproduction. Metabolism: Clinical and Experimental. 70: 152-159. PMID 28403939 DOI: 10.1016/J.Metabol.2016.12.004  0.739
2017 Xu Y, O'Malley BW, Elmquist JK. Brain nuclear receptors and body weight regulation. The Journal of Clinical Investigation. 127: 1172-1180. PMID 28218618 DOI: 10.1172/Jci88891  0.596
2016 Hinton AO, Yang Y, Quick AP, Xu P, Reddy CL, Yan X, Reynolds CL, Tong Q, Zhu L, Xu J, Wehrens XH, Xu Y, Reddy AK. SRC-1 Regulates Blood Pressure and Aortic Stiffness in Female Mice. Plos One. 11: e0168644. PMID 28006821 DOI: 10.1371/Journal.Pone.0168644  0.536
2016 He Y, Shu G, Yang Y, Xu P, Xia Y, Wang C, Saito K, Hinton A, Yan X, Liu C, Wu Q, Tong Q, Xu Y. A Small Potassium Current in AgRP/NPY Neurons Regulates Feeding Behavior and Energy Metabolism. Cell Reports. 17: 1807-1818. PMID 27829152 DOI: 10.1016/J.Celrep.2016.10.044  0.787
2016 Kaneko K, Xu P, Cordonier EL, Chen SS, Ng A, Xu Y, Morozov A, Fukuda M. Neuronal Rap1 Regulates Energy Balance, Glucose Homeostasis, and Leptin Actions. Cell Reports. 16: 3003-3015. PMID 27626668 DOI: 10.1016/J.Celrep.2016.08.039  0.606
2016 Xu P, He Y, Cao X, Valencia-Torres L, Yan X, Saito K, Wang C, Yang Y, Hinton A, Zhu L, Shu G, Myers MG, Wu Q, Tong Q, Heisler LK, ... Xu Y, et al. Activation of Serotonin 2C Receptors in Dopamine Neurons Inhibits Binge-like Eating in Mice. Biological Psychiatry. PMID 27516377 DOI: 10.1016/J.Biopsych.2016.06.005  0.802
2016 Sisley SR, Arble DM, Chambers AP, Gutierrez-Aguilar R, He Y, Xu Y, Gardner D, Moore DD, Seeley RJ, Sandoval DA. "Hypothalamic Vitamin D Improves Glucose Homeostasis and Reduces Weight". Diabetes. PMID 27217488 DOI: 10.2337/Db16-0309  0.654
2016 Lee JH, Lin L, Xu P, Saito K, Wei Q, Meadows AG, Bongmba OY, Pradhan G, Zheng H, Xu Y, Sun Y. Neuronal deletion of ghrelin receptor almost completely prevents diet-induced obesity. Diabetes. PMID 27207529 DOI: 10.2337/Db15-1587  0.689
2016 Hu F, Xu Y, Liu F. Hypothalamic Roles of mTOR Complex I: Integration of nutrient and hormone signals to regulate energy homeostasis. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00121.2016. PMID 27166282 DOI: 10.1152/ajpendo.00121.2016  0.318
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2016 Saito K, He Y, Yang Y, Zhu L, Wang C, Xu P, Hinton AO, Yan X, Zhao J, Fukuda M, Tong Q, Clegg DJ, Xu Y. PI3K in the ventromedial hypothalamic nucleus mediates estrogenic actions on energy expenditure in female mice. Scientific Reports. 6: 23459. PMID 26988598 DOI: 10.1038/Srep23459  0.765
2016 Meng F, Han Y, Srisai D, Belakhov V, Farias M, Xu Y, Palmiter RD, Baasov T, Wu Q. New inducible genetic method reveals critical roles of GABA in the control of feeding and metabolism. Proceedings of the National Academy of Sciences of the United States of America. PMID 26976589 DOI: 10.1073/Pnas.1602049113  0.469
2016 Saito K, He Y, Yan X, Yang Y, Wang C, Xu P, Hinton AO, Shu G, Yu L, Tong Q, Xu Y. Visualizing estrogen receptor-α-expressing neurons using a new ERα-ZsGreen reporter mouse line. Metabolism: Clinical and Experimental. 65: 522-32. PMID 26975544 DOI: 10.1016/J.Metabol.2015.12.011  0.747
2016 Xu Y, Chang JT, Myers MG, Xu Y, Tong Q. Euglycemia Restoration by Central Leptin in Type 1 Diabetes Requires STAT3 Signaling but Not Fast-Acting Neurotransmitter Release. Diabetes. PMID 26822087 DOI: 10.2337/Db15-1160  0.406
2016 Fan S, Dakshinamoorthy J, Kim ER, Xu Y, Huang C, Tong Q. An Indirect Action Contributes to C-Fos Induction in Paraventricular Hypothalamic Nucleus by Neuropeptide Y. Scientific Reports. 6: 19980. PMID 26813148 DOI: 10.1038/Srep19980  0.434
2015 Zhu L, Xu P, Cao X, Yang Y, Hinton AO, Xia Y, Saito K, Yan X, Zou F, Ding H, Wang C, Yan C, Saha P, Khan SA, Zhao J, ... Xu Y, et al. The ERα-PI3K Cascade in Pro-opiomelanocortin Progenitor Neurons Regulates Feeding and Glucose Balance in Female Mice. Endocrinology. en20151660. PMID 26375425 DOI: 10.1210/En.2015-1660  0.638
2015 Yan C, He Y, Xu Y, Shu G, Wang C, Yang Y, Saito K, Xu P, Hinton AO, Yan X, Yu L, Wu Q, Tso P, Tong Q, Xu Y. Apolipoprotein A-IV Inhibits AgRP/NPY Neurons and Activates POMC Neurons in the Arcuate Nucleus. Neuroendocrinology. PMID 26337236 DOI: 10.1159/000439436  0.75
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2015 Yan C, Yang Y, Saito K, Xu P, Wang C, Hinton AO, Yan X, Wu Q, Tong Q, Elmquist JK, Fukuda M, Xu Y. Meta-chlorophenylpiperazine enhances leptin sensitivity in diet-induced obese mice. British Journal of Pharmacology. 172: 3510-21. PMID 25817043 DOI: 10.1111/Bph.13141  0.623
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2015 Wu Z, Kim ER, Sun H, Xu Y, Mangieri LR, Li DP, Pan HL, Xu Y, Arenkiel BR, Tong Q. GABAergic projections from lateral hypothalamus to paraventricular hypothalamic nucleus promote feeding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 3312-8. PMID 25716832 DOI: 10.1523/Jneurosci.3720-14.2015  0.449
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2014 Scott MM, Xu Y, Elias CF, Williams KW. Central regulation of food intake, body weight, energy expenditure, and glucose homeostasis. Frontiers in Neuroscience. 8: 384. PMID 25520610 DOI: 10.3389/Fnins.2014.00384  0.584
2014 Shu G, Lu NS, Zhu XT, Xu Y, Du MQ, Xie QP, Zhu CJ, Xu Q, Wang SB, Wang LN, Gao P, Xi QY, Zhang YL, Jiang QY. Phloretin promotes adipocyte differentiation in vitro and improves glucose homeostasis in vivo. The Journal of Nutritional Biochemistry. 25: 1296-308. PMID 25283330 DOI: 10.1016/J.Jnutbio.2014.07.007  0.354
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2014 Xu Y, Kim ER, Fan S, Xia Y, Xu Y, Huang C, Tong Q. Profound and rapid reduction in body temperature induced by the melanocortin receptor agonists. Biochemical and Biophysical Research Communications. 451: 184-9. PMID 25065745 DOI: 10.1016/J.Bbrc.2014.07.079  0.381
2013 Xu Y, Wu Z, Sun H, Zhu Y, Kim ER, Lowell BB, Arenkiel BR, Xu Y, Tong Q. Glutamate mediates the function of melanocortin receptor 4 on Sim1 neurons in body weight regulation. Cell Metabolism. 18: 860-70. PMID 24315371 DOI: 10.1016/J.Cmet.2013.11.003  0.527
2013 Berglund ED, Liu C, Sohn JW, Liu T, Kim MH, Lee CE, Vianna CR, Williams KW, Xu Y, Elmquist JK. Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis. The Journal of Clinical Investigation. 123: 5061-70. PMID 24177424 DOI: 10.1172/Jci70338  0.826
2013 Davis KE, D Neinast M, Sun K, M Skiles W, D Bills J, A Zehr J, Zeve D, D Hahner L, W Cox D, M Gent L, Xu Y, V Wang Z, A Khan S, Clegg DJ. The sexually dimorphic role of adipose and adipocyte estrogen receptors in modulating adipose tissue expansion, inflammation, and fibrosis. Molecular Metabolism. 2: 227-42. PMID 24049737 DOI: 10.1016/J.Molmet.2013.05.006  0.349
2013 Shi X, Zhou F, Li X, Chang B, Li D, Wang Y, Tong Q, Xu Y, Fukuda M, Zhao JJ, Li D, Burrin DG, Chan L, Guan X. Central GLP-2 enhances hepatic insulin sensitivity via activating PI3K signaling in POMC neurons. Cell Metabolism. 18: 86-98. PMID 23823479 DOI: 10.1016/J.Cmet.2013.06.014  0.459
2013 Lee J, Moulik M, Fang Z, Saha P, Zou F, Xu Y, Nelson DL, Ma K, Moore DD, Yechoor VK. Bmal1 and β-cell clock are required for adaptation to circadian disruption, and their loss of function leads to oxidative stress-induced β-cell failure in mice. Molecular and Cellular Biology. 33: 2327-38. PMID 23547261 DOI: 10.1128/Mcb.01421-12  0.307
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2012 Tong Q, Xu Y. Central Leptin Regulation of Obesity and Fertility Current Obesity Reports. 1: 236-244. PMID 23243628 DOI: 10.1007/S13679-012-0025-8  0.372
2012 Xu Y, Nedungadiuli T, Gent L, Elias C, Elmquist JK, Clegg D. It's ALL in the Hypothalamus! Sex, Reproduction, and Obesity. Biology of Reproduction. 87: 34-34. DOI: 10.1093/Biolreprod/87.S1.34  0.516
2011 Xu Y, Faulkner LD, Hill JW. Cross-Talk between Metabolism and Reproduction: The Role of POMC and SF1 Neurons. Frontiers in Endocrinology. 2: 98. PMID 22649394 DOI: 10.3389/Fendo.2011.00098  0.671
2011 Xu Y, Elmquist JK, Fukuda M. Central nervous control of energy and glucose balance: focus on the central melanocortin system. Annals of the New York Academy of Sciences. 1243: 1-14. PMID 22211889 DOI: 10.1111/J.1749-6632.2011.06248.X  0.632
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2011 Sohn JW, Xu Y, Jones JE, Wickman K, Williams KW, Elmquist JK. Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels. Neuron. 71: 488-97. PMID 21835345 DOI: 10.1016/J.Neuron.2011.06.012  0.799
2011 Kim KW, Zhao L, Donato J, Kohno D, Xu Y, Elias CF, Lee C, Parker KL, Elmquist JK. Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus. Proceedings of the National Academy of Sciences of the United States of America. 108: 10673-8. PMID 21636788 DOI: 10.1073/Pnas.1102364108  0.582
2011 Marino JS, Xu Y, Hill JW. Central insulin and leptin-mediated autonomic control of glucose homeostasis. Trends in Endocrinology and Metabolism: Tem. 22: 275-85. PMID 21489811 DOI: 10.1016/J.Tem.2011.03.001  0.565
2011 Kim KW, Sohn JW, Kohno D, Xu Y, Williams K, Elmquist JK. SF-1 in the ventral medial hypothalamic nucleus: a key regulator of homeostasis. Molecular and Cellular Endocrinology. 336: 219-23. PMID 21111025 DOI: 10.1016/J.Mce.2010.11.019  0.791
2010 Xu Y, Jones JE, Lauzon DA, Anderson JG, Balthasar N, Heisler LK, Zinn AR, Lowell BB, Elmquist JK. A serotonin and melanocortin circuit mediates D-fenfluramine anorexia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14630-4. PMID 21048120 DOI: 10.1523/Jneurosci.5412-09.2010  0.812
2010 Xu Y, Berglund ED, Sohn JW, Holland WL, Chuang JC, Fukuda M, Rossi J, Williams KW, Jones JE, Zigman JM, Lowell BB, Scherer PE, Elmquist JK. 5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver. Nature Neuroscience. 13: 1457-9. PMID 21037584 DOI: 10.1038/Nn.2664  0.81
2010 Xu Y, Hill JW, Fukuda M, Gautron L, Sohn JW, Kim KW, Lee CE, Choi MJ, Lauzon DA, Dhillon H, Lowell BB, Zigman JM, Zhao JJ, Elmquist JK. PI3K signaling in the ventromedial hypothalamic nucleus is required for normal energy homeostasis. Cell Metabolism. 12: 88-95. PMID 20620998 DOI: 10.1016/J.Cmet.2010.05.002  0.804
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2009 Hill JW, Xu Y, Preitner F, Fukuda M, Cho YR, Luo J, Balthasar N, Coppari R, Cantley LC, Kahn BB, Zhao JJ, Elmquist JK. Phosphatidyl inositol 3-kinase signaling in hypothalamic proopiomelanocortin neurons contributes to the regulation of glucose homeostasis. Endocrinology. 150: 4874-82. PMID 19819947 DOI: 10.1210/En.2009-0454  0.839
2009 Xu Y, Krukoff TL. Adrenomedullin in the rostral ventrolateral medulla inhibits baroreflex control of heart rate : a role for protein kinase A British Journal of Pharmacology. 148: 70-77. PMID 16501581 DOI: 10.1038/Sj.Bjp.0706698  0.303
2008 Xu Y, Jones JE, Kohno D, Williams KW, Lee CE, Choi MJ, Anderson JG, Heisler LK, Zigman JM, Lowell BB, Elmquist JK. 5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis. Neuron. 60: 582-9. PMID 19038216 DOI: 10.1016/J.Neuron.2008.09.033  0.827
2007 Xu Y, Krukoff TL. Adrenomedullin Stimulates Nitric Oxide Production from Primary Rat Hypothalamic Neurons: Roles of Calcium and Phosphatases Molecular Pharmacology. 72: 112-120. PMID 17446268 DOI: 10.1124/Mol.106.033761  0.357
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