Year |
Citation |
Score |
2019 |
Bernardi RE, Olevska A, Morella I, Fasano S, Santos E, Brambilla R, Spanagel R. The inhibition of RasGRF2, but not RasGRF1, alters cocaine reward in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31182637 DOI: 10.1523/Jneurosci.1120-18.2019 |
0.324 |
|
2018 |
McWilliams TG, Barini E, Pohjolan-Pirhonen R, Brooks SP, Singh F, Burel S, Balk K, Kumar A, Montava-Garriga L, Prescott AR, Hassoun SM, Mouton-Liger F, Ball G, Hills R, Knebel A, ... ... Brambilla R, et al. Phosphorylation of Parkin at serine 65 is essential for its activation . Open Biology. 8. PMID 30404819 DOI: 10.1098/Rsob.180108 |
0.317 |
|
2018 |
Ruiz-DeDiego I, Fasano S, Solís O, Garcia-Montes JR, Brea J, Loza MI, Brambilla R, Moratalla R. Genetic enhancement of Ras-ERK pathway does not aggravate L-DOPA-induced dyskinesia in mice but prevents the decrease induced by lovastatin. Scientific Reports. 8: 15381. PMID 30337665 DOI: 10.1038/S41598-018-33713-3 |
0.343 |
|
2018 |
Pucilowska J, Vithayathil J, Pagani M, Kelly C, Karlo JC, Robol C, Morella I, Gozzi A, Brambilla R, Landreth GE. Pharmacological Inhibition of ERK Signaling Rescues Pathophysiology and Behavioral Phenotype Associated with 16p11.2 Chromosomal Deletion in Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29934348 DOI: 10.1523/Jneurosci.0515-17.2018 |
0.337 |
|
2017 |
Arcuri L, Novello S, Frassineti M, Mercatelli D, Pisanò CA, Morella I, Fasano S, Journigan BV, Meyer ME, Polgar WE, Brambilla R, Zaveri NT, Morari M. Antiparkinsonian and antidyskinetic profiles of two novel potent and selective nociceptin/orphanin FQ receptor agonists. British Journal of Pharmacology. PMID 29232769 DOI: 10.1111/Bph.14123 |
0.351 |
|
2016 |
Papale A, d'Isa R, Menna E, Cerovic M, Solari N, Hardingham N, Cambiaghi M, Cursi M, Barbacid M, Leocani L, Fasano S, Matteoli M, Brambilla R. Severe Intellectual Disability and Enhanced Gamma-Aminobutyric Acidergic Synaptogenesis in a Novel Model of Rare RASopathies. Biological Psychiatry. PMID 27587266 DOI: 10.1016/J.Biopsych.2016.06.016 |
0.524 |
|
2016 |
Melgarejo da Rosa M, Yuanxiang P, Brambilla R, Kreutz MR, Karpova A. Synaptic GluN2B/CaMKII-α Signaling Induces Synapto-Nuclear Transport of ERK and Jacob. Frontiers in Molecular Neuroscience. 9: 66. PMID 27559307 DOI: 10.3389/Fnmol.2016.00066 |
0.356 |
|
2016 |
Papale A, Morella IM, Indrigo MT, Eugene Bernardi R, Marrone L, Marchisella F, Brancale A, Spanagel R, Brambilla R, Fasano S. Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitors. Elife. 5. PMID 27557444 DOI: 10.7554/Elife.17111 |
0.31 |
|
2016 |
Rosas M, Porru S, Fenu S, Ruiu S, Peana AT, Papale A, Brambilla R, Di Chiara G, Acquas E. Role of nucleus accumbens μ opioid receptors in the effects of morphine on ERK1/2 phosphorylation. Psychopharmacology. PMID 27245230 DOI: 10.1007/S00213-016-4340-8 |
0.318 |
|
2015 |
Bido S, Solari N, Indrigo M, D'Antoni A, Brambilla R, Morari M, Fasano S. Differential involvement of Ras-GRF1 and Ras-GRF2 in L-DOPA-induced dyskinesia. Annals of Clinical and Translational Neurology. 2: 662-78. PMID 26125041 DOI: 10.1002/Acn3.202 |
0.327 |
|
2015 |
Fossati G, Morini R, Corradini I, Antonucci F, Trepte P, Edry E, Sharma V, Papale A, Pozzi D, Defilippi P, Meier JC, Brambilla R, Turco E, Rosenblum K, Wanker EE, et al. Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis. Cell Death and Differentiation. PMID 25678324 DOI: 10.1038/Cdd.2014.227 |
0.303 |
|
2015 |
Cerovic M, Bagetta V, Pendolino V, Ghiglieri V, Fasano S, Morella I, Hardingham N, Heuer A, Papale A, Marchisella F, Giampà C, Calabresi P, Picconi B, Brambilla R. Derangement of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and extracellular signal-regulated kinase (ERK) dependent striatal plasticity in L-DOPA-induced dyskinesia. Biological Psychiatry. 77: 106-15. PMID 24844602 DOI: 10.1016/J.Biopsych.2014.04.002 |
0.364 |
|
2014 |
d'Isa R, Brambilla R, Fasano S. Behavioral methods for the study of the Ras-ERK pathway in memory formation and consolidation: passive avoidance and novel object recognition tests. Methods in Molecular Biology (Clifton, N.J.). 1120: 131-56. PMID 24470023 DOI: 10.1007/978-1-62703-791-4_9 |
0.327 |
|
2013 |
Cerovic M, d'Isa R, Tonini R, Brambilla R. Molecular and cellular mechanisms of dopamine-mediated behavioral plasticity in the striatum. Neurobiology of Learning and Memory. 105: 63-80. PMID 23827407 DOI: 10.1016/J.Nlm.2013.06.013 |
0.325 |
|
2012 |
Marti M, Rodi D, Li Q, Guerrini R, Fasano S, Morella I, Tozzi A, Brambilla R, Calabresi P, Simonato M, Bezard E, Morari M. Nociceptin/orphanin FQ receptor agonists attenuate L-DOPA-induced dyskinesias. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16106-19. PMID 23152595 DOI: 10.1523/Jneurosci.6408-11.2012 |
0.356 |
|
2012 |
Fisone G, Brambilla R. Neuronal signaling and behavior. Frontiers in Behavioral Neuroscience. 6: 72. PMID 23129996 DOI: 10.3389/Fnbeh.2012.00072 |
0.385 |
|
2011 |
Silingardi D, Angelucci A, De Pasquale R, Borsotti M, Squitieri G, Brambilla R, Putignano E, Pizzorusso T, Berardi N. ERK pathway activation bidirectionally affects visual recognition memory and synaptic plasticity in the perirhinal cortex. Frontiers in Behavioral Neuroscience. 5: 84. PMID 22232579 DOI: 10.3389/Fnbeh.2011.00084 |
0.337 |
|
2011 |
d'Isa R, Clapcote SJ, Voikar V, Wolfer DP, Giese KP, Brambilla R, Fasano S. Mice Lacking Ras-GRF1 Show Contextual Fear Conditioning but not Spatial Memory Impairments: Convergent Evidence from Two Independently Generated Mouse Mutant Lines. Frontiers in Behavioral Neuroscience. 5: 78. PMID 22164138 DOI: 10.3389/Fnbeh.2011.00078 |
0.352 |
|
2011 |
Fasano S, Brambilla R. Ras-ERK Signaling in Behavior: Old Questions and New Perspectives. Frontiers in Behavioral Neuroscience. 5: 79. PMID 22131969 DOI: 10.3389/Fnbeh.2011.00079 |
0.368 |
|
2010 |
Fasano S, Bezard E, D'Antoni A, Francardo V, Indrigo M, Qin L, Doveró S, Cerovic M, Cenci MA, Brambilla R. Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia. Proceedings of the National Academy of Sciences of the United States of America. 107: 21824-9. PMID 21115823 DOI: 10.1073/Pnas.1012071107 |
0.339 |
|
2010 |
Indrigo M, Papale A, Orellana D, Brambilla R. Lentiviral vectors to study the differential function of ERK1 and ERK2 MAP kinases. Methods in Molecular Biology (Clifton, N.J.). 661: 205-20. PMID 20811985 DOI: 10.1007/978-1-60761-795-2_12 |
0.358 |
|
2009 |
Fasano S, Pittenger C, Brambilla R. Inhibition of CREB activity in the dorsal portion of the striatum potentiates behavioral responses to drugs of abuse. Frontiers in Behavioral Neuroscience. 3: 29. PMID 19826621 DOI: 10.3389/Neuro.08.029.2009 |
0.311 |
|
2009 |
Fasano S, D'Antoni A, Orban PC, Valjent E, Putignano E, Vara H, Pizzorusso T, Giustetto M, Yoon B, Soloway P, Maldonado R, Caboche J, Brambilla R. Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) controls activation of extracellular signal-regulated kinase (ERK) signaling in the striatum and long-term behavioral responses to cocaine. Biological Psychiatry. 66: 758-68. PMID 19446794 DOI: 10.1016/J.Biopsych.2009.03.014 |
0.379 |
|
2008 |
Marchi M, D'Antoni A, Formentini I, Parra R, Brambilla R, Ratto GM, Costa M. The N-terminal domain of ERK1 accounts for the functional differences with ERK2. Plos One. 3: e3873. PMID 19052640 DOI: 10.1371/Journal.Pone.0003873 |
0.367 |
|
2006 |
Vantaggiato C, Formentini I, Bondanza A, Bonini C, Naldini L, Brambilla R. ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially. Journal of Biology. 5: 14. PMID 16805921 DOI: 10.1186/Jbiol38 |
0.354 |
|
2006 |
Givogri MI, Galbiati F, Fasano S, Amadio S, Perani L, Superchi D, Morana P, Del Carro U, Marchesini S, Brambilla R, Wrabetz L, Bongarzone E. Oligodendroglial progenitor cell therapy limits central neurological deficits in mice with metachromatic leukodystrophy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3109-19. PMID 16554462 DOI: 10.1523/Jneurosci.4366-05.2006 |
0.301 |
|
2006 |
Pittenger C, Fasano S, Mazzocchi-Jones D, Dunnett SB, Kandel ER, Brambilla R. Impaired bidirectional synaptic plasticity and procedural memory formation in striatum-specific cAMP response element-binding protein-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2808-13. PMID 16525060 DOI: 10.1523/Jneurosci.5406-05.2006 |
0.31 |
|
2005 |
Biffi A, Capotondo A, Quattrini A, Carro UD, Brambilla R, Fasano S, Marchesini S, Bordignon C, Naldini L. 426. Cure of Established Disease and Direct Evidence of Cellular Cross-Correction in the Nervous System of Metachromatic Leukodystrophy Mice after HSC-Based Gene Therapy Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.428 |
0.318 |
|
2004 |
Biffi A, Visigalli I, Quattrini A, Bertani I, Palma MD, Carro UD, Brambilla R, Marchesini S, Bordignon C, Naldini L. 41. Ex Vivo Gene Therapy Provides a Unique Therapeutic Benefit and Corrects Metachromatic (MLD) and Globoid (GLD) Leukodystrophy in the Mouse Models Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.05.064 |
0.304 |
|
2003 |
Brambilla R. Targeting Ras/ERK signaling in the striatum: Will it help? Molecular Psychiatry. 8: 366-368. PMID 12740591 DOI: 10.1038/Sj.Mp.4001291 |
0.35 |
|
2002 |
Fasano S, Brambilla R. Cellular mechanisms of striatum-dependent behavioral plasticity and drug addiction Current Molecular Medicine. 2: 649-665. PMID 12420804 DOI: 10.2174/1566524023362005 |
0.305 |
|
2002 |
Mazzucchelli C, Vantaggiato C, Ciamei A, Fasano S, Pakhotin P, Krezel W, Welzl H, Wolfer DP, Pagès G, Valverde O, Marowsky A, Porrazzo A, Orban PC, Maldonado R, Ehrengruber MU, ... ... Brambilla R, et al. Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory. Neuron. 34: 807-20. PMID 12062026 DOI: 10.1016/S0896-6273(02)00716-X |
0.371 |
|
2001 |
Tonini R, Franceschetti S, Parolaro D, Sala M, Mancinelli E, Tininini S, Brusetti R, Sancini G, Brambilla R, Martegani E, Sturani E, Zippel R. Involvement of CDC25Mm/Ras-GRF1-dependent signaling in the control of neuronal excitability. Molecular and Cellular Neurosciences. 18: 691-701. PMID 11749043 DOI: 10.1006/Mcne.2001.1050 |
0.324 |
|
1999 |
Innocenti M, Zippel R, Brambilla R, Sturani E. CDC25(Mm)/Ras-GRF1 regulates both Ras and Rac signaling pathways Febs Letters. 460: 357-362. PMID 10544264 DOI: 10.1016/S0014-5793(99)01374-5 |
0.336 |
|
1999 |
Orban PC, Chapman PF, Brambilla R. Is the Ras-MAPK signalling pathway necessary for long-term memory formation? Trends in Neurosciences. 22: 38-44. PMID 10088998 DOI: 10.1016/S0166-2236(98)01306-X |
0.384 |
|
1998 |
Bergemann AD, Zhang L, Chiang MK, Brambilla R, Klein R, Flanagan JG. Ephrin-B3, a ligand for the receptor EphB3, expressed at the midline of the developing neural tube. Oncogene. 16: 471-80. PMID 9484836 DOI: 10.1038/Sj.Onc.1201557 |
0.401 |
|
1997 |
Brambilla R, Gnesutta N, Minichiello L, White G, Roylance AJ, Herron CE, Ramsey M, Wolfer DP, Cestari V, Rossi-Arnaud C, Grant SG, Chapman PF, Lipp HP, Sturani E, Klein R. A role for the Ras signalling pathway in synaptic transmission and long-term memory. Nature. 390: 281-6. PMID 9384379 DOI: 10.1038/36849 |
0.638 |
|
1997 |
Labrador JP, Brambilla R, Klein R. The N-terminal globular domain of Eph receptors is sufficient for ligand binding and receptor signaling. The Embo Journal. 16: 3889-97. PMID 9233799 DOI: 10.1093/Emboj/16.13.3889 |
0.719 |
|
1996 |
Brambilla R, Brückner K, Orioli D, Bergemann AD, Flanagan JG, Klein R. Similarities and Differences in the Way Transmembrane-Type Ligands Interact with the Elk Subclass of Eph Receptors Molecular and Cellular Neurosciences. 8: 199-209. PMID 8954633 |
0.353 |
|
1996 |
Brambilla R, Brückner K, Orioli D, Bergemann AD, Flanagan JG, Klein R. Similarities and differences in the way transmembrane-type ligands interact with the Elk subclass of Eph receptors Molecular and Cellular Neurosciences. 8: 199-209. PMID 8918835 DOI: 10.1006/Mcne.1996.0057 |
0.453 |
|
1995 |
Brambilla R, Klein R. Telling axons where to grow: a role for Eph receptor tyrosine kinases in guidance. Molecular and Cellular Neurosciences. 6: 487-95. PMID 8742266 DOI: 10.1006/Mcne.1995.0001 |
0.34 |
|
1995 |
Bergemann AD, Cheng HJ, Brambilla R, Klein R, Flanagan JG. ELF-2, a new member of the Eph ligand family, is segmentally expressed in mouse embryos in the region of the hindbrain and newly forming somites. Molecular and Cellular Biology. 15: 4921-9. PMID 7651410 DOI: 10.1128/Mcb.15.9.4921 |
0.662 |
|
1995 |
Brambilla R, Schnapp A, Casagranda F, Labrador JP, Bergemann AD, Flanagan JG, Pasquale EB, Klein R. Membrane-bound LERK2 ligand can signal through three different Eph-related receptor tyrosine kinases. The Embo Journal. 14: 3116-26. PMID 7621826 DOI: 10.1002/J.1460-2075.1995.Tb07314.X |
0.729 |
|
1994 |
Klein R, Silos-Santiago I, Smeyne RJ, Lira SA, Brambilla R, Bryant S, Zhang L, Snider WD, Barbacid M. Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements. Nature. 368: 249-51. PMID 8145824 DOI: 10.1038/368249A0 |
0.692 |
|
1989 |
Sturani E, Brambilla R, Morello L, Cattaneo MG, Zippel R, Alberghina L. Effect of the different dimeric forms of the platelet-derived growth factor on cellular responses in mouse Swiss 3T3 fibroblasts Febs Letters. 255: 191-195. PMID 2551728 DOI: 10.1016/0014-5793(89)81089-0 |
0.365 |
|
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