Ruth Slack - Publications

Affiliations: 
Cellular and Molecular Medicine University of Ottawa, Ottawa, ON, Canada 
Area:
Neurogenesis - Neuronal cell death
Website:
http://www.med.uottawa.ca/ruthslack/

80 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Huang T, González YR, Qu D, Huang E, Safarpour F, Wang E, Joselin A, Im DS, Callaghan SM, Boonying W, Julian L, Dunwoodie SL, Slack RS, Park DS. The pro-death role of Cited2 in stroke is regulated by E2F1/4 transcription factors. The Journal of Biological Chemistry. PMID 30967472 DOI: 10.1074/Jbc.Ra119.007941  0.355
2019 Boonying W, Joselin A, Huang E, Qu D, Safarpour F, Iyirhiaro GO, Rodriguez Gonzalez Y, Callaghan SM, Slack RS, Figeys D, Chung YH, Park DS. Pink1 regulates FKBP5 interaction with AKT/PHLPP and protects neurons from neurotoxin stress induced by MPP. Journal of Neurochemistry. PMID 30734931 DOI: 10.1111/Jnc.14683  0.349
2017 Iyirhiaro GO, Soon Im D, Boonying W, Callaghan SM, During MJ, Slack RS, Park DS. Cdc25A is a critical mediator of ischemic neuronal death in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28607169 DOI: 10.1523/Jneurosci.3017-16.2017  0.373
2017 Fong BC, Slack RS. RB: An essential player in adult neurogenesis. Neurogenesis (Austin, Tex.). 4: e1270382. PMID 28229086 DOI: 10.1080/23262133.2016.1270382  0.763
2016 Vandenbosch R, Clark A, Fong BC, Omais S, Jaafar C, Dugal-Tessier D, Dhaliwal J, Lagace DC, Park DS, Ghanem N, Slack RS. RB regulates the production and the survival of newborn neurons in the embryonic and adult dentate gyrus. Hippocampus. PMID 27325572 DOI: 10.1002/Hipo.22613  0.794
2015 Dugal-Tessier D, Vandenbosch R, Khacho M, Weijts B, Park DS, Leone G, de Bruin A, Slack RS. Absence of atypical E2f leads to ventriculomegaly. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 47: 14. PMID 26531370 DOI: 10.1016/J.Ijdevneu.2015.04.048  0.476
2015 Julian LM, Liu Y, Pakenham CA, Dugal-Tessier D, Ruzhynsky V, Bae S, Tsai SY, Leone G, Slack RS, Blais A. Tissue-specific targeting of cell fate regulatory genes by E2f factors. Cell Death and Differentiation. PMID 25909886 DOI: 10.1038/Cdd.2015.36  0.373
2015 Svoboda DS, Clark A, Park DS, Slack RS. Induction of protein deletion through in utero electroporation to define deficits in neuronal migration in transgenic models. Journal of Visualized Experiments : Jove. 51983. PMID 25650557 DOI: 10.3791/51983  0.319
2014 Parsanejad M, Zhang Y, Qu D, Irrcher I, Rousseaux MW, Aleyasin H, Kamkar F, Callaghan S, Slack RS, Mak TW, Lee S, Figeys D, Park DS. Regulation of the VHL/HIF-1 pathway by DJ-1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8043-50. PMID 24899725 DOI: 10.1523/Jneurosci.1244-13.2014  0.311
2014 Iyirhiaro GO, Zhang Y, Estey C, O'Hare MJ, Safarpour F, Parsanejad M, Wang S, Abdel-Messih E, Callaghan SM, During MJ, Slack RS, Park DS. Regulation of ischemic neuronal death by E2F4-p130 protein complexes. The Journal of Biological Chemistry. 289: 18202-13. PMID 24828495 DOI: 10.1074/Jbc.M114.574145  0.427
2013 Svoboda DS, Paquin A, Park DS, Slack RS. Pocket proteins pRb and p107 are required for cortical lamination independent of apoptosis. Developmental Biology. 384: 101-13. PMID 24056077 DOI: 10.1016/J.Ydbio.2013.09.015  0.45
2013 Andrusiak MG, Vandenbosch R, Dick FA, Park DS, Slack RS. LXCXE-independent chromatin remodeling by Rb/E2f mediates neuronal quiescence. Cell Cycle (Georgetown, Tex.). 12: 1416-23. PMID 23574720 DOI: 10.4161/Cc.24527  0.782
2013 Mount MP, Zhang Y, Amini M, Callaghan S, Kulczycki J, Mao Z, Slack RS, Anisman H, Park DS. Perturbation of transcription factor Nur77 expression mediated by myocyte enhancer factor 2D (MEF2D) regulates dopaminergic neuron loss in response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). The Journal of Biological Chemistry. 288: 14362-71. PMID 23536182 DOI: 10.1074/Jbc.M112.439216  0.347
2013 Amini M, Ma CL, Farazifard R, Zhu G, Zhang Y, Vanderluit J, Zoltewicz JS, Hage F, Savitt JM, Lagace DC, Slack RS, Beique JC, Baudry M, Greer PA, Bergeron R, et al. Conditional disruption of calpain in the CNS alters dendrite morphology, impairs LTP, and promotes neuronal survival following injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5773-84. PMID 23536090 DOI: 10.1523/Jneurosci.4247-12.2013  0.344
2013 Julian LM, Vandenbosch R, Pakenham CA, Andrusiak MG, Nguyen AP, McClellan KA, Svoboda DS, Lagace DC, Park DS, Leone G, Blais A, Slack RS. Opposing regulation of Sox2 by cell-cycle effectors E2f3a and E2f3b in neural stem cells. Cell Stem Cell. 12: 440-52. PMID 23499385 DOI: 10.1016/J.Stem.2013.02.001  0.771
2013 Germain M, Nguyen AP, Khacho M, Patten DA, Screaton RA, Park DS, Slack RS. LKB1-regulated adaptive mechanisms are essential for neuronal survival following mitochondrial dysfunction. Human Molecular Genetics. 22: 952-62. PMID 23187960 DOI: 10.1093/hmg/dds500  0.313
2012 Andrusiak MG, Vandenbosch R, Park DS, Slack RS. The retinoblastoma protein is essential for survival of postmitotic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14809-14. PMID 23077065 DOI: 10.1523/Jneurosci.1912-12.2012  0.8
2012 Joselin AP, Hewitt SJ, Callaghan SM, Kim RH, Chung YH, Mak TW, Shen J, Slack RS, Park DS. ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons. Human Molecular Genetics. 21: 4888-903. PMID 22872702 DOI: 10.1093/Hmg/Dds325  0.326
2012 Ghanem N, Andrusiak MG, Svoboda D, Al Lafi SM, Julian LM, McClellan KA, De Repentigny Y, Kothary R, Ekker M, Blais A, Park DS, Slack RS. The Rb/E2F pathway modulates neurogenesis through direct regulation of the Dlx1/Dlx2 bigene cluster. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8219-30. PMID 22699903 DOI: 10.1523/Jneurosci.1344-12.2012  0.784
2012 Haque ME, Mount MP, Safarpour F, Abdel-Messih E, Callaghan S, Mazerolle C, Kitada T, Slack RS, Wallace V, Shen J, Anisman H, Park DS. Inactivation of Pink1 gene in vivo sensitizes dopamine-producing neurons to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and can be rescued by autosomal recessive Parkinson disease genes, Parkin or DJ-1. The Journal of Biological Chemistry. 287: 23162-70. PMID 22511790 DOI: 10.1074/Jbc.M112.346437  0.347
2011 Germain M, Slack RS. MCL-1 regulates the balance between autophagy and apoptosis. Autophagy. 7: 549-51. PMID 21412051 DOI: 10.4161/auto.7.5.15098  0.39
2011 Germain M, Nguyen AP, Le Grand JN, Arbour N, Vanderluit JL, Park DS, Opferman JT, Slack RS. MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner. The Embo Journal. 30: 395-407. PMID 21139567 DOI: 10.1038/Emboj.2010.327  0.347
2011 Andrusiak MG, McClellan KA, Dugal-Tessier D, Julian LM, Rodrigues SP, Park DS, Kennedy TE, Slack RS. Rb/E2F regulates expression of neogenin during neuronal migration. Molecular and Cellular Biology. 31: 238-47. PMID 21059867 DOI: 10.1128/Mcb.00378-10  0.8
2010 Huang E, Qu D, Zhang Y, Venderova K, Haque ME, Rousseaux MW, Slack RS, Woulfe JM, Park DS. The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death. Nature Cell Biology. 12: 563-71. PMID 20473298 DOI: 10.1038/Ncb2058  0.309
2010 Biswas SC, Zhang Y, Iyirhiaro G, Willett RT, Rodriguez Gonzalez Y, Cregan SP, Slack RS, Park DS, Greene LA. Sertad1 plays an essential role in developmental and pathological neuron death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3973-82. PMID 20237268 DOI: 10.1523/Jneurosci.6421-09.2010  0.407
2010 Aleyasin H, Rousseaux MW, Marcogliese PC, Hewitt SJ, Irrcher I, Joselin AP, Parsanejad M, Kim RH, Rizzu P, Callaghan SM, Slack RS, Mak TW, Park DS. DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway. Proceedings of the National Academy of Sciences of the United States of America. 107: 3186-91. PMID 20133695 DOI: 10.1073/Pnas.0914876107  0.3
2010 Zhang Y, Parsanejad M, Huang E, Qu D, Aleyasin H, Rousseaux MW, Gonzalez YR, Cregan SP, Slack RS, Park DS. Pim-1 kinase as activator of the cell cycle pathway in neuronal death induced by DNA damage. Journal of Neurochemistry. 112: 497-510. PMID 19895669 DOI: 10.1111/J.1471-4159.2009.06476.X  0.364
2010 Andrusiak M, McClellan K, Dugal‐Tessier D, Park D, Kennedy T, Slack R. [P1.51]: Rb/E2F regulation of neogenin modulates netrin‐1 induced neuronal migration International Journal of Developmental Neuroscience. 28: 672-672. DOI: 10.1016/J.Ijdevneu.2010.07.091  0.79
2010 Dugal‐Tessier D, Andrusiak M, Ruzhynsky V, Julian L, Park D, Slack R. [P1.50]: E2F4 is essential for development of the ventral telencephalon International Journal of Developmental Neuroscience. 28: 672-672. DOI: 10.1016/J.Ijdevneu.2010.07.090  0.728
2010 Svoboda D, Vandenbosch R, Ghanem N, Park D, Slack R. [P1.49]: A requirement for pRb during olfactory bulb and hippocampal neurogenesis International Journal of Developmental Neuroscience. 28: 671-671. DOI: 10.1016/J.Ijdevneu.2010.07.089  0.514
2009 McClellan KA, Vanderluit JL, Julian LM, Andrusiak MG, Dugal-Tessier D, Park DS, Slack RS. The p107/E2F pathway regulates fibroblast growth factor 2 responsiveness in neural precursor cells. Molecular and Cellular Biology. 29: 4701-13. PMID 19564414 DOI: 10.1128/Mcb.01767-08  0.772
2008 Arbour N, Vanderluit JL, Le Grand JN, Jahani-Asl A, Ruzhynsky VA, Cheung EC, Kelly MA, MacKenzie AE, Park DS, Opferman JT, Slack RS. Mcl-1 is a key regulator of apoptosis during CNS development and after DNA damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6068-78. PMID 18550749 DOI: 10.1523/Jneurosci.4940-07.2008  0.411
2008 Gonzalez YR, Zhang Y, Behzadpoor D, Cregan S, Bamforth S, Slack RS, Park DS. CITED2 signals through peroxisome proliferator-activated receptor-gamma to regulate death of cortical neurons after DNA damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5559-69. PMID 18495890 DOI: 10.1523/Jneurosci.1014-08.2008  0.348
2007 Qu D, Rashidian J, Mount MP, Aleyasin H, Parsanejad M, Lira A, Haque E, Zhang Y, Callaghan S, Daigle M, Rousseaux MW, Slack RS, Albert PR, Vincent I, Woulfe JM, et al. Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease. Neuron. 55: 37-52. PMID 17610816 DOI: 10.1016/J.Neuron.2007.05.033  0.308
2007 Vanderluit JL, Wylie CA, McClellan KA, Ghanem N, Fortin A, Callaghan S, MacLaurin JG, Park DS, Slack RS. The Retinoblastoma family member p107 regulates the rate of progenitor commitment to a neuronal fate. The Journal of Cell Biology. 178: 129-39. PMID 17591923 DOI: 10.1083/Jcb.200703176  0.456
2007 Ruzhynsky VA, McClellan KA, Vanderluit JL, Jeong Y, Furimsky M, Park DS, Epstein DJ, Wallace VA, Slack RS. Cell cycle regulator E2F4 is essential for the development of the ventral telencephalon. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5926-35. PMID 17537963 DOI: 10.1523/Jneurosci.1538-07.2007  0.334
2007 Jahani-Asl A, Cheung EC, Neuspiel M, MacLaurin JG, Fortin A, Park DS, McBride HM, Slack RS. Mitofusin 2 protects cerebellar granule neurons against injury-induced cell death. The Journal of Biological Chemistry. 282: 23788-98. PMID 17537722 DOI: 10.1074/jbc.M703812200  0.348
2007 Cheung EC, McBride HM, Slack RS. Mitochondrial dynamics in the regulation of neuronal cell death. Apoptosis : An International Journal On Programmed Cell Death. 12: 979-92. PMID 17453163 DOI: 10.1007/s10495-007-0745-5  0.325
2007 McClellan KA, Ruzhynsky VA, Douda DN, Vanderluit JL, Ferguson KL, Chen D, Bremner R, Park DS, Leone G, Slack RS. Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions. Molecular and Cellular Biology. 27: 4825-43. PMID 17452454 DOI: 10.1128/Mcb.02100-06  0.479
2007 Mount MP, Lira A, Grimes D, Smith PD, Faucher S, Slack R, Anisman H, Hayley S, Park DS. Involvement of interferon-gamma in microglial-mediated loss of dopaminergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3328-37. PMID 17376993 DOI: 10.1523/Jneurosci.5321-06.2007  0.38
2006 Zhang Y, Qu D, Morris EJ, O'Hare MJ, Callaghan SM, Slack RS, Geller HM, Park DS. The Chk1/Cdc25A pathway as activators of the cell cycle in neuronal death induced by camptothecin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8819-28. PMID 16928871 DOI: 10.1523/JNEUROSCI.2593-06.2006  0.394
2006 Smith PD, Mount MP, Shree R, Callaghan S, Slack RS, Anisman H, Vincent I, Wang X, Mao Z, Park DS. Calpain-regulated p35/cdk5 plays a central role in dopaminergic neuron death through modulation of the transcription factor myocyte enhancer factor 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 440-7. PMID 16407541 DOI: 10.1523/Jneurosci.2875-05.2006  0.333
2006 Crocker SJ, Hayley SP, Smith PD, Mount MP, Lamba WR, Callaghan SM, Slack RS, Park DS. Regulation of axotomy-induced dopaminergic neuron death and c-Jun phosphorylation by targeted inhibition of cdc42 or mixed lineage kinase. Journal of Neurochemistry. 96: 489-99. PMID 16336220 DOI: 10.1111/J.1471-4159.2005.03568.X  0.318
2006 McClellan K, Douda D, Ferguson K, Vanderluit J, Schuurmans C, Polleux F, Slack R. [P206]: A novel function for the Rb/E2F signaling pathway in regulating neuronal migration during cortical development International Journal of Developmental Neuroscience. 24: 584-584. DOI: 10.1016/J.Ijdevneu.2006.09.266  0.489
2006 Vanderluit J, Wylie C, Fortin A, Callaghan S, MacLaurin J, Park D, Slack R. [P58]: P107, a retinoblastoma family member, negatively regulates neural precursor cell numbers by repressing Hes1 International Journal of Developmental Neuroscience. 24: 521-521. DOI: 10.1016/J.Ijdevneu.2006.09.121  0.412
2005 Ferguson KL, McClellan KA, Vanderluit JL, McIntosh WC, Schuurmans C, Polleux F, Slack RS. A cell-autonomous requirement for the cell cycle regulatory protein, Rb, in neuronal migration. The Embo Journal. 24: 4381-91. PMID 16308563 DOI: 10.1038/Sj.Emboj.7600887  0.473
2005 O'Hare MJ, Kushwaha N, Zhang Y, Aleyasin H, Callaghan SM, Slack RS, Albert PR, Vincent I, Park DS. Differential roles of nuclear and cytoplasmic cyclin-dependent kinase 5 in apoptotic and excitotoxic neuronal death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8954-66. PMID 16192386 DOI: 10.1523/Jneurosci.2899-05.2005  0.372
2005 Rashidian J, Iyirhiaro G, Aleyasin H, Rios M, Vincent I, Callaghan S, Bland RJ, Slack RS, During MJ, Park DS. Multiple cyclin-dependent kinases signals are critical mediators of ischemia/hypoxic neuronal death in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 102: 14080-5. PMID 16166266 DOI: 10.1073/Pnas.0500099102  0.401
2005 Cheung EC, Melanson-Drapeau L, Cregan SP, Vanderluit JL, Ferguson KL, McIntosh WC, Park DS, Bennett SA, Slack RS. Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 1324-34. PMID 15703386 DOI: 10.1523/Jneurosci.4261-04.2005  0.31
2005 Bérubé NG, Mangelsdorf M, Jagla M, Vanderluit J, Garrick D, Gibbons RJ, Higgs DR, Slack RS, Picketts DJ. The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis. The Journal of Clinical Investigation. 115: 258-67. PMID 15668733 DOI: 10.1172/JCI22329  0.425
2004 Cregan SP, Arbour NA, Maclaurin JG, Callaghan SM, Fortin A, Cheung EC, Guberman DS, Park DS, Slack RS. p53 activation domain 1 is essential for PUMA upregulation and p53-mediated neuronal cell death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10003-12. PMID 15525786 DOI: 10.1523/Jneurosci.2114-04.2004  0.423
2004 Cheung EC, Slack RS. Emerging role for ERK as a key regulator of neuronal apoptosis. Science's Stke : Signal Transduction Knowledge Environment. 2004: PE45. PMID 15383672 DOI: 10.1126/stke.2512004pe45  0.381
2004 Vanderluit JL, Ferguson KL, Nikoletopoulou V, Parker M, Ruzhynsky V, Alexson T, McNamara SM, Park DS, Rudnicki M, Slack RS. p107 regulates neural precursor cells in the mammalian brain. The Journal of Cell Biology. 166: 853-63. PMID 15353549 DOI: 10.1083/Jcb.200403156  0.348
2004 Chen D, Livne-bar I, Vanderluit JL, Slack RS, Agochiya M, Bremner R. Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma. Cancer Cell. 5: 539-51. PMID 15193257 DOI: 10.1016/j.ccr.2004.05.025  0.306
2004 Fortin A, MacLaurin JG, Arbour N, Cregan SP, Kushwaha N, Callaghan SM, Park DS, Albert PR, Slack RS. The proapoptotic gene SIVA is a direct transcriptional target for the tumor suppressors p53 and E2F1. The Journal of Biological Chemistry. 279: 28706-14. PMID 15105421 DOI: 10.1074/Jbc.M400376200  0.395
2004 Aleyasin H, Cregan SP, Iyirhiaro G, O'Hare MJ, Callaghan SM, Slack RS, Park DS. Nuclear factor-(kappa)B modulates the p53 response in neurons exposed to DNA damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2963-73. PMID 15044535 DOI: 10.1523/Jneurosci.0155-04.2004  0.307
2004 Hayley S, Crocker SJ, Smith PD, Shree T, Jackson-Lewis V, Przedborski S, Mount M, Slack R, Anisman H, Park DS. Regulation of dopaminergic loss by Fas in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2045-53. PMID 14985447 DOI: 10.1523/Jneurosci.4564-03.2004  0.348
2003 Keramaris E, Hirao A, Slack RS, Mak TW, Park DS. Ataxia telangiectasia-mutated protein can regulate p53 and neuronal death independent of Chk2 in response to DNA damage. The Journal of Biological Chemistry. 278: 37782-9. PMID 12857758 DOI: 10.1074/jbc.M304049200  0.398
2003 Sedarous M, Keramaris E, O'Hare M, Melloni E, Slack RS, Elce JS, Greer PA, Park DS. Calpains mediate p53 activation and neuronal death evoked by DNA damage. The Journal of Biological Chemistry. 278: 26031-8. PMID 12721303 DOI: 10.1074/Jbc.M302833200  0.305
2002 Cregan SP, Fortin A, MacLaurin JG, Callaghan SM, Cecconi F, Yu SW, Dawson TM, Dawson VL, Park DS, Kroemer G, Slack RS. Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death. The Journal of Cell Biology. 158: 507-17. PMID 12147675 DOI: 10.1083/Jcb.200202130  0.38
2002 Ferguson KL, Vanderluit JL, Hébert JM, McIntosh WC, Tibbo E, MacLaurin JG, Park DS, Wallace VA, Vooijs M, McConnell SK, Slack RS. Telencephalon-specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical development. The Embo Journal. 21: 3337-46. PMID 12093735 DOI: 10.1093/Emboj/Cdf338  0.337
2001 Fortin A, Cregan SP, MacLaurin JG, Kushwaha N, Hickman ES, Thompson CS, Hakim A, Albert PR, Cecconi F, Helin K, Park DS, Slack RS. APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death. The Journal of Cell Biology. 155: 207-16. PMID 11591730 DOI: 10.1083/Jcb.200105137  0.461
2001 Simpson MT, MacLaurin JG, Xu D, Ferguson KL, Vanderluit JL, Davoli MA, Roy S, Nicholson DW, Robertson GS, Park DS, Slack RS. Caspase 3 deficiency rescues peripheral nervous system defect in retinoblastoma nullizygous mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7089-98. PMID 11549719 DOI: 10.1523/Jneurosci.21-18-07089.2001  0.368
2001 Morris EJ, Keramaris E, Rideout HJ, Slack RS, Dyson NJ, Stefanis L, Park DS. Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5017-26. PMID 11438577  0.328
2001 Morris EJ, Keramaris E, Rideout HJ, Slack RS, Dyson NJ, Stefanis L, Park DS. Cyclin-Dependent Kinases and P53 Pathways Are Activated Independently and Mediate Bax Activation in Neurons after DNA Damage The Journal of Neuroscience. 21: 5017-5026. DOI: 10.1523/Jneurosci.21-14-05017.2001  0.328
2000 Osuga H, Osuga S, Wang F, Fetni R, Hogan MJ, Slack RS, Hakim AM, Ikeda JE, Park DS. Cyclin-dependent kinases as a therapeutic target for stroke. Proceedings of the National Academy of Sciences of the United States of America. 97: 10254-9. PMID 10944192 DOI: 10.1073/Pnas.170144197  0.336
2000 Cregan SP, MacLaurin J, Gendron TF, Callaghan SM, Park DS, Parks RJ, Graham FL, Morley P, Slack RS. Helper-dependent adenovirus vectors: their use as a gene delivery system to neurons. Gene Therapy. 7: 1200-9. PMID 10918488 DOI: 10.1038/Sj.Gt.3301208  0.44
2000 Ferguson KL, Callaghan SM, O'Hare MJ, Park DS, Slack RS. The Rb-CDK4/6 signaling pathway is critical in neural precursor cell cycle regulation. The Journal of Biological Chemistry. 275: 33593-600. PMID 10915795 DOI: 10.1074/Jbc.M004879200  0.43
2000 Hou ST, Callaghan D, Fournier MC, Hill I, Kang L, Massie B, Morley P, Murray C, Rasquinha I, Slack R, MacManus JP. The transcription factor E2F1 modulates apoptosis of neurons. Journal of Neurochemistry. 75: 91-100. PMID 10854251 DOI: 10.1046/J.1471-4159.2000.0750091.X  0.496
2000 O'Hare MJ, Hou ST, Morris EJ, Cregan SP, Xu Q, Slack RS, Park DS. Induction and modulation of cerebellar granule neuron death by E2F-1. The Journal of Biological Chemistry. 275: 25358-64. PMID 10851232 DOI: 10.1074/Jbc.M001725200  0.348
2000 Giovanni A, Keramaris E, Morris EJ, Hou ST, O'Hare M, Dyson N, Robertson GS, Slack RS, Park DS. E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3. The Journal of Biological Chemistry. 275: 11553-60. PMID 10766769 DOI: 10.1074/Jbc.275.16.11553  0.362
1999 Cregan SP, MacLaurin JG, Craig CG, Robertson GS, Nicholson DW, Park DS, Slack RS. Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 7860-9. PMID 10479688 DOI: 10.1523/Jneurosci.19-18-07860.1999  0.406
1999 Giovanni A, Wirtz-Brugger F, Keramaris E, Slack R, Park DS. Involvement of cell cycle elements, cyclin-dependent kinases, pRb, and E2F x DP, in B-amyloid-induced neuronal death. The Journal of Biological Chemistry. 274: 19011-6. PMID 10383401 DOI: 10.1074/Jbc.274.27.19011  0.477
1999 Cregan SP, MacLaurin JG, Craig CG, Robertson GS, Nicholson DW, Park DS, Slack RS. Bax-Dependent Caspase-3 Activation Is a Key Determinant in p53-Induced Apoptosis in Neurons The Journal of Neuroscience. 19: 7860-7869. DOI: 10.1523/JNEUROSCI.19-18-07860.1999  0.307
1998 Gill RM, Slack R, Kiess M, Hamel PA. Regulation of expression and activity of distinct pRB, E2F, D-type cyclin, and CKI family members during terminal differentiation of P19 cells. Experimental Cell Research. 244: 157-70. PMID 9770359 DOI: 10.1006/Excr.1998.4197  0.439
1998 Slack RS, El-Bizri H, Wong J, Belliveau DJ, Miller FD. A critical temporal requirement for the retinoblastoma protein family during neuronal determination. The Journal of Cell Biology. 140: 1497-509. PMID 9508781 DOI: 10.1083/JCB.140.6.1497  0.623
1996 Slack RS, Miller FD. Viral vectors for modulating gene expression in neurons. Current Opinion in Neurobiology. 6: 576-83. PMID 8937820 DOI: 10.1016/S0959-4388(96)80088-2  0.516
1996 Slack RS, Belliveau DJ, Rosenberg M, Atwal J, Lochmüller H, Aloyz R, Haghighi A, Lach B, Seth P, Cooper E, Miller FD. Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons. The Journal of Cell Biology. 135: 1085-96. PMID 8922388 DOI: 10.1083/Jcb.135.4.1085  0.774
1996 Miller FD, Rogers D, Bamji SX, Slack RS, Gloster A. Analysis and manipulation of neuronal gene expression using the Tα1 α-tubulin promoter Seminars in Neuroscience. 8: 117-124. DOI: 10.1006/Smns.1996.0016  0.759
1995 Slack RS, Skerjanc IS, Lach B, Craig J, Jardine K, McBurney MW. Cells differentiating into neuroectoderm undergo apoptosis in the absence of functional retinoblastoma family proteins. The Journal of Cell Biology. 129: 779-88. PMID 7730411 DOI: 10.1083/Jcb.129.3.779  0.355
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