Lloyd Greene - Publications

Affiliations: 
Columbia University, New York, NY 
Area:
neuronal death, neural development

150 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Aimé P, Karuppagounder SS, Rao A, Chen Y, Burke RE, Ratan RR, Greene LA. The drug adaptaquin blocks ATF4/CHOP-dependent pro-death Trib3 induction and protects in cellular and mouse models of Parkinson's disease. Neurobiology of Disease. 104725. PMID 31911115 DOI: 10.1016/j.nbd.2019.104725  0.327
2018 Park S, Burke RE, Kareva T, Kholodilov N, Aimé P, Franke TF, Levy O, Greene LA. Context-dependent expression of a conditionally-inducible form of active Akt. Plos One. 13: e0197899. PMID 29920520 DOI: 10.1371/journal.pone.0197899  0.455
2018 Corona C, Pasini S, Liu J, Amar F, Greene LA, Shelanski ML. Activating Transcription Factor 4 (ATF4) regulates neuronal activity by controlling GABAR trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29875265 DOI: 10.1523/JNEUROSCI.3350-17.2018  0.341
2018 Liu J, Amar F, Corona C, So RWL, Andrews SJ, Nagy PL, Shelanski ML, Greene LA. Brain-Derived Neurotrophic Factor Elevates Activating Transcription Factor 4 (ATF4) in Neurons and Promotes ATF4-Dependent Induction of. Frontiers in Molecular Neuroscience. 11: 62. PMID 29599707 DOI: 10.3389/Fnmol.2018.00062  0.381
2018 Sun X, Aimé P, Dai D, Ramalingam N, Crary JF, Burke RE, Greene LA, Levy OA. Guanabenz promotes neuronal survival via enhancement of ATF4 and parkin expression in models of Parkinson disease. Experimental Neurology. PMID 29432724 DOI: 10.1016/J.Expneurol.2018.01.015  0.366
2017 Biswas SC, Sanphui P, Chatterjee N, Kemeny S, Greene LA. Cdc25A phosphatase: a key cell cycle protein that regulates neuron death in disease and development. Cell Death & Disease. 8: e2692. PMID 28333146 DOI: 10.1038/cddis.2017.115  0.421
2016 Chatterjee N, Sanphui P, Kemeny S, Greene LA, Biswas SC. Role and regulation of Cdc25A phosphatase in neuron death induced by NGF deprivation or β-amyloid. Cell Death Discovery. 2: 16083. PMID 28028440 DOI: 10.1038/cddiscovery.2016.83  0.466
2016 Pasini S, Liu J, Corona C, Peze-Heidsieck E, Shelanski M, Greene LA. Activating Transcription Factor 4 (ATF4) modulates Rho GTPase levels and function via regulation of RhoGDIα. Scientific Reports. 6: 36952. PMID 27841340 DOI: 10.1038/srep36952  0.421
2015 Aimé P, Sun X, Zareen N, Rao A, Berman Z, Volpicelli-Daley L, Bernd P, Crary JF, Levy OA, Greene LA. Trib3 Is Elevated in Parkinson's Disease and Mediates Death in Parkinson's Disease Models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 10731-49. PMID 26224857 DOI: 10.1523/Jneurosci.0614-15.2015  0.737
2014 Romaní-Aumedes J, Canal M, Martín-Flores N, Sun X, Pérez-Fernández V, Wewering S, Fernández-Santiago R, Ezquerra M, Pont-Sunyer C, Lafuente A, Alberch J, Luebbert H, Tolosa E, Levy OA, Greene LA, et al. Parkin loss of function contributes to RTP801 elevation and neurodegeneration in Parkinson's disease. Cell Death & Disease. 5: e1364. PMID 25101677 DOI: 10.1038/Cddis.2014.333  0.412
2013 Zareen N, Biswas SC, Greene LA. A feed-forward loop involving Trib3, Akt and FoxO mediates death of NGF-deprived neurons. Cell Death and Differentiation. 20: 1719-30. PMID 24212932 DOI: 10.1038/cdd.2013.128  0.794
2013 Jean YY, Ribe EM, Pero ME, Moskalenko M, Iqbal Z, Marks LJ, Greene LA, Troy CM. Caspase-2 is essential for c-Jun transcriptional activation and Bim induction in neuron death. The Biochemical Journal. 455: 15-25. PMID 23815625 DOI: 10.1042/Bj20130556  0.466
2013 Sun X, Liu J, Crary JF, Malagelada C, Sulzer D, Greene LA, Levy OA. ATF4 protects against neuronal death in cellular Parkinson's disease models by maintaining levels of parkin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2398-407. PMID 23392669 DOI: 10.1523/Jneurosci.2292-12.2013  0.318
2012 Grau CM, Greene LA. Use of PC12 cells and rat superior cervical ganglion sympathetic neurons as models for neuroprotective assays relevant to Parkinson's disease. Methods in Molecular Biology (Clifton, N.J.). 846: 201-11. PMID 22367813 DOI: 10.1007/978-1-61779-536-7_18  0.365
2012 Chalazonitis A, Gershon MD, Greene LA. Cell death and the developing enteric nervous system. Neurochemistry International. 61: 839-47. PMID 22342822 DOI: 10.1016/J.Neuint.2012.01.028  0.379
2012 Wilhelm M, Kukekov NV, Schmit TL, Biagas KV, Sproul AA, Gire S, Maes ME, Xu Z, Greene LA. Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein. The Journal of Biological Chemistry. 287: 2247-56. PMID 22128169 DOI: 10.1074/Jbc.M111.269431  0.821
2012 Lee HY, Angelastro JM, Kenney AM, Mason CA, Greene LA. Reciprocal actions of ATF5 and Shh in proliferation of cerebellar granule neuron progenitor cells. Developmental Neurobiology. 72: 789-804. PMID 22095825 DOI: 10.1002/Dneu.20979  0.344
2011 Willett RT, Greene LA. Gata2 is required for migration and differentiation of retinorecipient neurons in the superior colliculus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4444-55. PMID 21430145 DOI: 10.1523/Jneurosci.4616-10.2011  0.799
2011 Malagelada C, López-Toledano MA, Willett RT, Jin ZH, Shelanski ML, Greene LA. RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 3186-96. PMID 21368030 DOI: 10.1523/Jneurosci.4011-10.2011  0.802
2010 Biswas SC, Zhang Y, Iyirhiaro G, Willett RT, Rodriguez Gonzalez Y, Cregan SP, Slack RS, Park DS, Greene LA. Sertad1 plays an essential role in developmental and pathological neuron death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3973-82. PMID 20237268 DOI: 10.1523/Jneurosci.6421-09.2010  0.828
2010 Malagelada C, Jin ZH, Jackson-Lewis V, Przedborski S, Greene LA. Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1166-75. PMID 20089925 DOI: 10.1523/JNEUROSCI.3944-09.2010  0.356
2009 Sproul AA, Xu Z, Wilhelm M, Gire S, Greene LA. Cbl negatively regulates JNK activation and cell death. Cell Research. 19: 950-61. PMID 19546888 DOI: 10.1038/Cr.2009.74  0.815
2009 Zareen N, Greene LA. Protocol for culturing sympathetic neurons from rat superior cervical ganglia (SCG). Journal of Visualized Experiments : Jove. PMID 19229183 DOI: 10.3791/988  0.758
2009 Lee HY, Greene LA, Mason CA, Manzini MC. Isolation and culture of post-natal mouse cerebellar granule neuron progenitor cells and neurons. Journal of Visualized Experiments : Jove. PMID 19229177 DOI: 10.3791/990  0.37
2009 Levy OA, Malagelada C, Greene LA. Cell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps. Apoptosis : An International Journal On Programmed Cell Death. 14: 478-500. PMID 19165601 DOI: 10.1007/s10495-008-0309-3  0.355
2009 Greene LA, Lee HY, Angelastro JM. The transcription factor ATF5: role in neurodevelopment and neural tumors. Journal of Neurochemistry. 108: 11-22. PMID 19046351 DOI: 10.1111/J.1471-4159.2008.05749.X  0.321
2008 Malagelada C, Jin ZH, Greene LA. RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 14363-71. PMID 19118169 DOI: 10.1523/JNEUROSCI.3928-08.2008  0.349
2008 Biswas SC, Buteau J, Greene LA. Glucagon-like peptide-1 (GLP-1) diminishes neuronal degeneration and death caused by NGF deprivation by suppressing Bim induction. Neurochemical Research. 33: 1845-51. PMID 18351462 DOI: 10.1007/s11064-008-9646-4  0.439
2008 Lee HY, Angelastro JM, Kenney AM, Mason C, Greene L. Regulation of ATF5 during cerebellar granule neuron progenitor proliferation and differentiation International Journal of Developmental Neuroscience. 26: 847. DOI: 10.1016/J.Ijdevneu.2008.09.066  0.459
2007 Wilhelm M, Kukekov NV, Xu Z, Greene LA. Identification of POSH2, a novel homologue of the c-Jun N-terminal kinase scaffold protein POSH. Developmental Neuroscience. 29: 355-62. PMID 17762203 DOI: 10.1159/000105476  0.835
2007 Biswas SC, Shi Y, Sproul A, Greene LA. Pro-apoptotic Bim induction in response to nerve growth factor deprivation requires simultaneous activation of three different death signaling pathways. The Journal of Biological Chemistry. 282: 29368-74. PMID 17702754 DOI: 10.1074/Jbc.M702634200  0.734
2007 Biswas SC, Shi Y, Vonsattel JP, Leung CL, Troy CM, Greene LA. Bim is elevated in Alzheimer's disease neurons and is required for beta-amyloid-induced neuronal apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 893-900. PMID 17251431 DOI: 10.1523/JNEUROSCI.3524-06.2007  0.374
2007 Greene LA, Liu DX, Troy CM, Biswas SC. Cell cycle molecules define a pathway required for neuron death in development and disease. Biochimica Et Biophysica Acta. 1772: 392-401. PMID 17229557 DOI: 10.1016/j.bbadis.2006.12.003  0.477
2007 Wilhelm M, Xu Z, Kukekov NV, Gire S, Greene LA. Proapoptotic Nix activates the JNK pathway by interacting with POSH and mediates death in a Parkinson disease model. The Journal of Biological Chemistry. 282: 1288-95. PMID 17095503 DOI: 10.1074/Jbc.M607038200  0.834
2006 Malagelada C, Ryu EJ, Biswas SC, Jackson-Lewis V, Greene LA. RTP801 is elevated in Parkinson brain substantia nigral neurons and mediates death in cellular models of Parkinson's disease by a mechanism involving mammalian target of rapamycin inactivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9996-10005. PMID 17005863 DOI: 10.1523/JNEUROSCI.3292-06.2006  0.339
2006 Kukekov NV, Xu Z, Greene LA. Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs. The Journal of Biological Chemistry. 281: 15517-24. PMID 16571722 DOI: 10.1074/Jbc.M601056200  0.805
2006 Xu Z, Greene LA. Activation of the apoptotic JNK pathway through the Rac1-binding scaffold protein POSH. Methods in Enzymology. 406: 479-89. PMID 16472680 DOI: 10.1016/S0076-6879(06)06036-8  0.57
2006 Xu Z, Sproul A, Wang W, Kukekov N, Greene LA. Siah1 interacts with the scaffold protein POSH to promote JNK activation and apoptosis. The Journal of Biological Chemistry. 281: 303-12. PMID 16230351 DOI: 10.1074/Jbc.M509060200  0.773
2006 Wang Q, Maniati M, Jabado O, Pavlaki M, Troy CM, Greene LA, Stefanis L. RAIDD is required for apoptosis of PC12 cells and sympathetic neurons induced by trophic factor withdrawal. Cell Death and Differentiation. 13: 75-83. PMID 15947787 DOI: 10.1038/sj.cdd.4401690  0.402
2006 Teng KK, Angelastro JM, Cunningham ME, Greene LA. Cultured PC12 cells: A model for neuronal function, differentiation, and survival Cell Biology, Four-Volume Set. 1: 171-176. DOI: 10.1016/B978-012164730-8/50022-8  0.733
2005 Xu Z, Kukekov NV, Greene LA. Regulation of apoptotic c-Jun N-terminal kinase signaling by a stabilization-based feed-forward loop. Molecular and Cellular Biology. 25: 9949-59. PMID 16260609 DOI: 10.1128/Mcb.25.22.9949-9959.2005  0.813
2005 Biswas SC, Ryu E, Park C, Malagelada C, Greene LA. Puma and p53 play required roles in death evoked in a cellular model of Parkinson disease. Neurochemical Research. 30: 839-45. PMID 16187218 DOI: 10.1007/s11064-005-6877-5  0.341
2005 Biswas SC, Liu DX, Greene LA. Bim is a direct target of a neuronal E2F-dependent apoptotic pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8349-58. PMID 16162916 DOI: 10.1523/JNEUROSCI.1570-05.2005  0.49
2005 Silva RM, Ries V, Oo TF, Yarygina O, Jackson-Lewis V, Ryu EJ, Lu PD, Marciniak SJ, Ron D, Przedborski S, Kholodilov N, Greene LA, Burke RE. CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism. Journal of Neurochemistry. 95: 974-86. PMID 16135078 DOI: 10.1111/J.1471-4159.2005.03428.X  0.359
2005 Liu DX, Nath N, Chellappan SP, Greene LA. Regulation of neuron survival and death by p130 and associated chromatin modifiers. Genes & Development. 19: 719-32. PMID 15769944 DOI: 10.1101/Gad.1296405  0.359
2005 Wilhelm M, Gire S, Xu Z, Kukekov NV, Greene LA. POSH REGULATES JNK ACTIVATION BY THE BH3-ONLY PROTEIN NIX. Critical Care Medicine. 33: A16. DOI: 10.1097/00003246-200512002-00064  0.778
2004 Liu DX, Biswas SC, Greene LA. B-myb and C-myb play required roles in neuronal apoptosis evoked by nerve growth factor deprivation and DNA damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8720-5. PMID 15470138 DOI: 10.1523/JNEUROSCI.1821-04.2004  0.457
2004 Mc Gee MM, Greene LM, Ledwidge S, Campiani G, Nacci V, Lawler M, Williams DC, Zisterer DM. Selective induction of apoptosis by the pyrrolo-1,5-benzoxazepine 7-[[dimethylcarbamoyl]oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia cells occurs via the c-Jun NH2-terminal kinase-dependent phosphorylation and inactivation of Bcl-2 and Bcl-XL. The Journal of Pharmacology and Experimental Therapeutics. 310: 1084-95. PMID 15143129 DOI: 10.1124/Jpet.104.067561  0.341
2004 Greene LA, Biswas SC, Liu DX. Cell cycle molecules and vertebrate neuron death: E2F at the hub. Cell Death and Differentiation. 11: 49-60. PMID 14647236 DOI: 10.1038/sj.cdd.4401341  0.445
2004 Wilhelm M, Vannucci SJ, Kukekov NV, Xu Z, Greene LA. A NOVEL POSH HOMOLOGUE AND ITS ROLE IN NEURONAL APOPTOSIS Critical Care Medicine. 32: A98. DOI: 10.1097/00003246-200412001-00354  0.81
2003 Angelastro JM, Ignatova TN, Kukekov VG, Steindler DA, Stengren GB, Mendelsohn C, Greene LA. Regulated expression of ATF5 is required for the progression of neural progenitor cells to neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4590-600. PMID 12805299 DOI: 10.1523/Jneurosci.23-11-04590.2003  0.413
2003 Xu Z, Kukekov NV, Greene LA. POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis. The Embo Journal. 22: 252-61. PMID 12514131 DOI: 10.1093/Emboj/Cdg021  0.839
2002 Ryu EJ, Harding HP, Angelastro JM, Vitolo OV, Ron D, Greene LA. Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10690-8. PMID 12486162 DOI: 10.1523/Jneurosci.22-24-10690.2002  0.339
2002 Töröcsik B, Angelastro JM, Greene LA. The basic region and leucine zipper transcription factor MafK is a new nerve growth factor-responsive immediate early gene that regulates neurite outgrowth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8971-80. PMID 12388604 DOI: 10.1523/Jneurosci.22-20-08971.2002  0.429
2002 Biswas SC, Greene LA. Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation. The Journal of Biological Chemistry. 277: 49511-6. PMID 12388545 DOI: 10.1074/jbc.M208086200  0.487
2002 Angelastro JM, Töröcsik B, Greene LA. Nerve growth factor selectively regulates expression of transcripts encoding ribosomal proteins. Bmc Neuroscience. 3: 3. PMID 11922865 DOI: 10.1186/1471-2202-3-3  0.312
2002 Angelastro JM, Ryu EJ, Törõcsik B, Fiske BK, Greene LA. Blue-white selection step enhances the yield of SAGE concatemers. Biotechniques. 32: 484, 486. PMID 11911650 DOI: 10.2144/02323Bm02  0.618
2001 Liu DX, Greene LA. Regulation of neuronal survival and death by E2F-dependent gene repression and derepression Neuron. 32: 425-438. PMID 11709154 DOI: 10.1016/S0896-6273(01)00495-0  0.378
2001 Liu DX, Greene LA. Neuronal apoptosis at the G1/S cell cycle checkpoint Cell and Tissue Research. 305: 217-228. PMID 11545259 DOI: 10.1007/s004410100396  0.458
2001 Troy CM, Rabacchi SA, Hohl JB, Angelastro JM, Greene LA, Shelanski ML. Death in the balance: alternative participation of the caspase-2 and -9 pathways in neuronal death induced by nerve growth factor deprivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5007-16. PMID 11438576 DOI: 10.1523/Jneurosci.21-14-05007.2001  0.44
2001 Xu Z, Maroney AC, Dobrzanski P, Kukekov NV, Greene LA. The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis. Molecular and Cellular Biology. 21: 4713-24. PMID 11416147 DOI: 10.1128/Mcb.21.14.4713-4724.2001  0.846
2001 Valavanis C, Hu Y, Yang Y, Osborne BA, Chouaib S, Greene L, Ashwell JD, Schwartz LM. Model cell lines for the study of apoptosis in vitro. Methods in Cell Biology. 66: 417-36. PMID 11396014 DOI: 10.1016/S0091-679X(01)66019-9  0.333
2001 Maroney AC, Finn JP, Connors TJ, Durkin JT, Angeles T, Gessner G, Xu Z, Meyer SL, Savage MJ, Greene LA, Scott RW, Vaught JL. Cep-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family. The Journal of Biological Chemistry. 276: 25302-8. PMID 11325962 DOI: 10.1074/Jbc.M011601200  0.601
2001 Troy CM, Rabacchi SA, Xu Z, Maroney AC, Connors TJ, Shelanski ML, Greene LA. beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation. Journal of Neurochemistry. 77: 157-64. PMID 11279271 DOI: 10.1046/J.1471-4159.2001.T01-1-00218.X  0.559
2001 Angelastro JM, Moon NY, Liu DX, Yang AS, Greene LA, Franke TF. Characterization of a novel isoform of caspase-9 that inhibits apoptosis. The Journal of Biological Chemistry. 276: 12190-200. PMID 11278518 DOI: 10.1074/Jbc.M009523200  0.375
2001 Stefanis L, Kholodilov N, Rideout HJ, Burke RE, Greene LA. Synuclein-1 is selectively up-regulated in response to nerve growth factor treatment in PC12 cells. Journal of Neurochemistry. 76: 1165-76. PMID 11181836 DOI: 10.1046/j.1471-4159.2001.00114.x  0.321
2000 Park DS, Obeidat A, Giovanni A, Greene LA. Cell cycle regulators in neuronal death evoked by excitotoxic stress: implications for neurodegeneration and its treatment. Neurobiology of Aging. 21: 771-81. PMID 11124421 DOI: 10.1016/S0197-4580(00)00220-7  0.57
2000 Park DS, Morris EJ, Bremner R, Keramaris E, Padmanabhan J, Rosenbaum M, Shelanski ML, Geller HM, Greene LA. Involvement of retinoblastoma family members and E2F/DP complexes in the death of neurons evoked by DNA damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3104-14. PMID 10777774 DOI: 10.1523/Jneurosci.20-09-03104.2000  0.603
2000 Mukai J, Hachiya T, Shoji-Hoshino S, Kimura MT, Nadano D, Suvanto P, Hanaoka T, Li Y, Irie S, Greene LA, Sato TA. NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR Journal of Biological Chemistry. 275: 17566-17570. PMID 10764727 DOI: 10.1074/jbc.C000140200  0.37
1999 Maroney AC, Finn JP, Bozyczko-Coyne D, O'Kane TM, Neff NT, Tolkovsky AM, Park DS, Yan CY, Troy CM, Greene LA. CEP-1347 (KT7515), an inhibitor of JNK activation, rescues sympathetic neurons and neuronally differentiated PC12 cells from death evoked by three distinct insults. Journal of Neurochemistry. 73: 1901-12. PMID 10537048  0.664
1999 Padmanabhan J, Park DS, Greene LA, Shelanski ML. Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8747-56. PMID 10516294 DOI: 10.1523/Jneurosci.19-20-08747.1999  0.614
1999 Stefanis L, Park DS, Friedman WJ, Greene LA. Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6235-47. PMID 10414953 DOI: 10.1523/Jneurosci.19-15-06235.1999  0.546
1998 Park DS, Morris EJ, Padmanabhan J, Shelanski ML, Geller HM, Greene LA. Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents. The Journal of Cell Biology. 143: 457-67. PMID 9786955 DOI: 10.1083/Jcb.143.2.457  0.585
1998 Ferrari G, Greene LA. Promotion of neuronal survival by GM1 ganglioside. Phenomenology and mechanism of action Annals of the New York Academy of Sciences. 845: 263-273. PMID 9668360 DOI: 10.1111/j.1749-6632.1998.tb09679.x  0.337
1998 Van Irene CY, Greene LA. Prevention of PC12 cell death by N-acetylcysteine requires activation of the Ras pathway Journal of Neuroscience. 18: 4042-4049. PMID 9592085  0.401
1998 Angelastro JM, Ho CL, Frappier T, Liem RK, Greene LA. Peripherin is tyrosine-phosphorylated at its carboxyl-terminal tyrosine. Journal of Neurochemistry. 70: 540-9. PMID 9453548 DOI: 10.1046/J.1471-4159.1998.70020540.X  0.323
1998 Park DS, Morris EJ, Stefanis L, Troy CM, Shelanski ML, Geller HM, Greene LA. Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 830-40. PMID 9437005 DOI: 10.1523/Jneurosci.18-03-00830.1998  0.584
1998 Stefanis L, Troy CM, Qi H, Shelanski ML, Greene LA. Caspase-2 (Nedd-2) Processing and Death of Trophic Factor-Deprived PC12 Cells and Sympathetic Neurons Occur Independently of Caspase-3 (CPP32)-Like Activity The Journal of Neuroscience. 18: 9204-9215. DOI: 10.1523/JNEUROSCI.18-22-09204.1998  0.426
1998 Farinelli SE, Greene LA, Friedman WJ. Neuroprotective Actions of Dipyridamole on Cultured CNS Neurons The Journal of Neuroscience. 18: 5112-5123. DOI: 10.1523/Jneurosci.18-14-05112.1998  0.302
1997 Park DS, Stefanis L, Greene LA. Ordering the multiple pathways of apoptosis. Trends in Cardiovascular Medicine. 7: 294-301. PMID 21235899 DOI: 10.1016/S1050-1738(97)00090-X  0.511
1997 Park DS, Levine B, Ferrari G, Greene LA. Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 8975-83. PMID 9364045 DOI: 10.1523/Jneurosci.17-23-08975.1997  0.635
1997 Stefanis L, Troy CM, Qi H, Greene LA. Inhibitors of trypsin-like serine proteases inhibit processing of the caspase Nedd-2 and protect PC12 cells and sympathetic neurons from death evoked by withdrawal of trophic support. Journal of Neurochemistry. 69: 1425-37. PMID 9326271 DOI: 10.1046/J.1471-4159.1997.69041425.X  0.433
1997 Troy CM, Stefanis L, Greene LA, Shelanski ML. Nedd2 is required for apoptosis after trophic factor withdrawal, but not superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1911-8. PMID 9045720 DOI: 10.1523/Jneurosci.17-06-01911.1997  0.446
1997 Park DS, Morris EJ, Greene LA, Geller HM. G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1256-70. PMID 9006970 DOI: 10.1523/Jneurosci.17-04-01256.1997  0.62
1997 Troy CM, Stefanis L, Greene LA, Shelanski ML. Mechanisms of neuronal degeneration: a final common pathway? Advances in Neurology. 72: 103-11. PMID 8993689  0.367
1996 Stefanis L, Park DS, Yan CY, Farinelli SE, Troy CM, Shelanski ML, Greene LA. Induction of CPP32-like activity in PC12 cells by withdrawal of trophic support. Dissociation from apoptosis. The Journal of Biological Chemistry. 271: 30663-71. PMID 8940042 DOI: 10.1074/Jbc.271.48.30663  0.571
1996 Peng X, Angelastro JM, Greene LA. Tyrosine phosphorylation of extracellular signal-regulated protein kinase 4 in response to growth factors Journal of Neurochemistry. 66: 1191-1197. PMID 8769883 DOI: 10.1046/J.1471-4159.1996.66031191.X  0.324
1996 Park DS, Stefanis L, Yan CY, Farinelli SE, Greene LA. Ordering the cell death pathway. Differential effects of BCL2, an interleukin-1-converting enzyme family protease inhibitor, and other survival agents on JNK activation in serum/nerve growth factor-deprived PC12 cells. The Journal of Biological Chemistry. 271: 21898-905. PMID 8702992 DOI: 10.1074/Jbc.271.36.21898  0.553
1996 Park DS, Farinelli SE, Greene LA. Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons. The Journal of Biological Chemistry. 271: 8161-9. PMID 8626506 DOI: 10.1074/Jbc.271.14.8161  0.65
1996 Troy CM, Derossi D, Prochiantz A, Greene LA, Shelanski ML. Downregulation of Cu/Zn superoxide dismutase leads to cell death via the nitric oxide-peroxynitrite pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 253-61. PMID 8613791 DOI: 10.1523/Jneurosci.16-01-00253.1996  0.478
1996 Farinelli SE, Park DS, Greene LA. Nitric oxide delays the death of trophic factor-deprived PC12 cells and sympathetic neurons by a cGMP-mediated mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 2325-34. PMID 8601812 DOI: 10.1523/Jneurosci.16-07-02325.1996  0.621
1995 Ferrari G, Anderson BL, Stephens RM, Kaplan DR, Greene LA. Prevention of apoptotic neuronal death by GM1 ganglioside. Involvement of Trk neurotrophin receptors. The Journal of Biological Chemistry. 270: 3074-80. PMID 7852388 DOI: 10.1074/jbc.270.7.3074  0.429
1995 Volonte C, Greene LA. Nerve growth factor-activated protein kinase N modulates the cAMP- dependent protein kinase Journal of Neuroscience Research. 40: 108-116. PMID 7714918 DOI: 10.1002/jnr.490400112  0.349
1995 Peng X, Greene LA, Kaplan DR, Stephens RM. Deletion of a conserved juxtamembrane sequence in Trk abolishes NGF-promoted neuritogenesis Neuron. 15: 395-406. PMID 7646892 DOI: 10.1016/0896-6273(95)90043-8  0.328
1995 O'Driscoll KR, Teng KK, Fabbro D, Greene LA, Weinstein IB. Selective translocation of protein kinase C-delta in PC12 cells during nerve growth factor-induced neuritogenesis Mol Biol Cell. 6: 449. PMID 7626808  0.747
1994 Teng KK, Greene LA.. KT5926 selectively inhibits nerve growth factor-dependent neurite elongation J Neurosci. 14: 2624. PMID 8182431  0.745
1993 Teng KK, Greene LA. Depolarization maintains neurites and priming of PC12 cells after nerve growth factor withdrawal J Neurosci. 13. PMID 8331389 DOI: 10.1523/Jneurosci.13-07-03124.1993  0.736
1993 Volonté C, Loeb DM, Greene LA. A purine analog-sensitive protein kinase activity associates with Trk nerve growth factor receptors Journal of Neurochemistry. 61: 664-672. PMID 7687657 DOI: 10.1111/j.1471-4159.1993.tb02171.x  0.333
1993 Batistatou A, Greene LA. Internucleosomal DNA cleavage and neuronal cell survival/death Journal of Cell Biology. 122: 523-532. PMID 7687603 DOI: 10.1083/Jcb.122.3.523  0.441
1993 Volonte C, Ross AH, Greene LA. Association of a purine-analogue-sensitive protein kinase activity with p75 nerve growth factor receptors Molecular Biology of the Cell. 4: 71-78. PMID 7680248 DOI: 10.1091/MBC.4.1.71  0.352
1993 Batistatou A, Merry D, Korsmeyer S, Greene L. Bcl-2 affects survival but not neuronal differentiation of PC12 cells The Journal of Neuroscience. 13: 4422-4428. DOI: 10.1523/Jneurosci.13-10-04422.1993  0.548
1992 Batistatou A, Volonte C, Greene LA. Nerve growth factor employs multiple pathways to induce primary response genes in PC12 cells Molecular Biology of the Cell. 3: 363-371. PMID 1627834 DOI: 10.1091/MBC.3.3.363  0.363
1992 Troy CM, Greene LA, Shelanski ML. Neurite outgrowth in peripherin-depleted PC12 cells. The Journal of Cell Biology. 117: 1085-92. PMID 1577867 DOI: 10.1083/jcb.117.5.1085  0.385
1992 Loeb DM, Tsao H, Cobb MH, Greene LA. NGF and other growth factors induce an association between ERK1 and the NGF receptor, gp140prototrk Neuron. 9: 1053-1065. PMID 1463607 DOI: 10.1016/0896-6273(92)90065-L  0.336
1992 Volonte C, Greene LA. 6-Methylmercaptopurine riboside is a potent and selective inhibitor of nerve growth factor-activated protein kinase N Journal of Neurochemistry. 58: 700-708. PMID 1309569 DOI: 10.1111/j.1471-4159.1992.tb09774.x  0.357
1991 Batistatou A, Greene LA. Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: Correlation with suppression of endonuclease activity Journal of Cell Biology. 115: 461-471. PMID 1655805 DOI: 10.1083/jcb.115.2.461  0.422
1991 Loeb DM, Maragos J, Martin-Zanca D, Chao MV, Parada LF, Greene LA. The trk proto-oncogene rescues NGF responsiveness in mutant NGF-nonresponsive PC12 cell lines. Cell. 66: 961-6. PMID 1653650 DOI: 10.1016/0092-8674(91)90441-Z  0.307
1990 Troy CM, Brown K, Greene LA, Shelanski ML. Ontogeny of the neuronal intermediate filament protein, peripherin, in the mouse embryo. Neuroscience. 36: 217-37. PMID 2215919 DOI: 10.1016/0306-4522(90)90364-A  0.335
1990 Volonte C, Greene LA. Nerve growth factor (NGF) responses by non-neuronal cells: Detection by assay of a novel NGF-activated protein kinase Growth Factors. 2: 321-331. PMID 2159763 DOI: 10.3109/08977199009167027  0.384
1990 Rowland-Gagne E, Greene LA. Multiple pathways of N-kinase activation in PC12 cells Journal of Neurochemistry. 54: 424-433. PMID 2153751 DOI: 10.1111/j.1471-4159.1990.tb01890.x  0.348
1989 Volonte C, Rukenstein A, Loeb DM, Greene LA. Differential inhibition of nerve growth factor responses by purine analogues: Correlation with inhibiton of a nerve growth factor-activated protein kinase Journal of Cell Biology. 109: 2395-2403. PMID 2553745 DOI: 10.1083/JCB.109.5.2395  0.382
1989 Aletta JM, Shelanski ML, Greene LA. Phosphorylation of the peripherin 58-kDa neuronal intermediate filament protein Journal of Biological Chemistry. 264: 4619-4627. DOI: 10.1016/s0021-9258(18)83788-7  0.367
1988 Aletta JM, Angeletti R, Liem RK, Purcell C, Shelanski ML, Greene LA. Relationship between the nerve growth factor-regulated clone 73 gene product and the 58-kilodalton neuronal intermediate filament protein (peripherin). Journal of Neurochemistry. 51: 1317-20. PMID 3418352 DOI: 10.1111/J.1471-4159.1988.Tb03104.X  0.352
1988 Rydel RE, Greene LA. cAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor Proceedings of the National Academy of Sciences of the United States of America. 85: 1257-1261. PMID 2829221 DOI: 10.1073/PNAS.85.4.1257  0.441
1987 Leonard DG, Ziff EB, Greene LA. Identification and characterization of mRNAs regulated by nerve growth factor in PC12 cells. Molecular and Cellular Biology. 7: 3156-67. PMID 3670309  0.312
1987 Greene LA, Aletta JM, Rukenstein A, Green SH. PC12 pheochromocytoma cells: culture, nerve growth factor treatment, and experimental exploitation. Methods in Enzymology. 147: 207-16. PMID 3670084 DOI: 10.1016/0076-6879(87)47111-5  0.619
1986 Margolis RK, Greene LA, Margolis RU. Poly(N-acetyllactosaminyl) oligosaccharides in glycoproteins of PC12 pheochromocytoma cells and sympathetic neurons Biochemistry. 25: 3463-3468. PMID 3755358 DOI: 10.1021/Bi00359A055  0.309
1986 Greenberg ME, Ziff EB, Greene LA. Stimulation of neuronal acetylcholine receptors induces rapid gene transcription. Science (New York, N.Y.). 234: 80-3. PMID 3749894 DOI: 10.1126/Science.3749894  0.319
1986 Black MM, Aletta JM, Greene LA. Regulation of microtubule composition and stability during nerve growth factor-promoted neurite outgrowth. The Journal of Cell Biology. 103: 545-57. PMID 3733878 DOI: 10.1083/Jcb.103.2.545  0.487
1986 Greene LA, Drexler SA, Connolly JL, Rukenstein A, Green SH. Selective inhibition of responses to nerve growth factor and of microtubule-associated protein phosphorylation by activators of adenylate cyclase. The Journal of Cell Biology. 103: 1967-78. PMID 3023392 DOI: 10.1083/Jcb.103.5.1967  0.633
1986 Green SH, Greene LA. A single Mr approximately 103,000 125I-beta-nerve growth factor-affinity-labeled species represents both the low and high affinity forms of the nerve growth factor receptor. The Journal of Biological Chemistry. 261: 15316-26. PMID 3021771  0.567
1986 Green SH, Rydel RE, Connolly JL, Greene LA. PC12 cell mutants that possess low- but not high-affinity nerve growth factor receptors neither respond to nor internalize nerve growth factor. The Journal of Cell Biology. 102: 830-43. PMID 3005338 DOI: 10.1083/Jcb.102.3.830  0.614
1986 Sajovic P, Moraru E, Greene L, Shelanski M. Selective staining of large projection neurons by monoclonal antibody to a glycoprotein of PC12 cells The Journal of Neuroscience. 6: 82-93. DOI: 10.1523/Jneurosci.06-01-00082.1986  0.403
1985 Burstein DE, Seeley PJ, Greene LA. Lithium ion inhibits nerve growth factor-induced neurite outgrowth and phosphorylation of nerve growth factor-mediated microtubule-associated proteins Journal of Cell Biology. 101: 862-870. PMID 4030895 DOI: 10.1083/JCB.101.3.862  0.322
1985 Richter-Landsberg C, Greene L, Shelanski M. Cell surface Thy-1-cross-reactive glycoprotein in cultured PC12 cells: modulation by nerve growth factor and association with the cytoskeleton The Journal of Neuroscience. 5: 468-476. DOI: 10.1523/Jneurosci.05-02-00468.1985  0.378
1983 Salton SR, Shelanski ML, Greene LA. Biochemical properties of the nerve growth factor-inducible large external (NILE) glycoprotein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 3: 2420-30. PMID 6655495 DOI: 10.1523/Jneurosci.03-12-02420.1983  0.4
1983 Salton SR, Richter-Landsberg C, Greene LA, Shelanski ML. Nerve growth factor-inducible large external (NILE) glycoprotein: studies of a central and peripheral neuronal marker. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 3: 441-54. PMID 6338160 DOI: 10.1523/Jneurosci.03-03-00441.1983  0.423
1983 Greene LA, Bernd P, Black MM, Burstein DE, Connolly JL, Rukenstein A, Seeley PJ. Genomic and non-genomic actions of nerve growth factor in development. Progress in Brain Research. 58: 347-57. PMID 6314431 DOI: 10.1016/S0079-6123(08)60036-9  0.477
1983 Seeley P, Keith C, Shelanski M, Greene L. Pressure microinjection of nerve growth factor and anti-nerve growth factor into the nucleus and cytoplasm: lack of effects on neurite outgrowth from pheochromocytoma cells The Journal of Neuroscience. 3: 1488-1494. DOI: 10.1523/Jneurosci.03-07-01488.1983  0.388
1982 Burstein DE, Greene LA. Nerve growth factor has both mitogenic and antimitogenic activity Developmental Biology. 94: 477-482. PMID 7152115 DOI: 10.1016/0012-1606(82)90364-5  0.309
1982 Black MM, Greene LA. Changes in the colchicine susceptibility of microtubules associated with neurite outgrowth: studies with nerve growth factor-responsive PC12 pheochromocytoma cells. The Journal of Cell Biology. 95: 379-86. PMID 7142295 DOI: 10.1083/Jcb.95.2.379  0.509
1982 Kouvelas ED, Greene LA. Development of muscarinic cholinergic receptors in chick embryo sympathetic ganglia. Developmental Neuroscience. 5: 375-8. PMID 7140584 DOI: 10.1159/000112696  0.597
1982 Burstein DE, Blumberg PM, Greene LA. Nerve growth factor-induced neuronal differentiation of PC12 pheochromocytoma cells: Lack of inhibition by a tumor promoter Brain Research. 247: 115-119. PMID 7127107 DOI: 10.1016/0006-8993(82)91033-2  0.373
1982 Greene LA, Burstein DE, Black MM. The role of transcription-dependent priming in nerve growth factor promoted neurite outgrowth. Developmental Biology. 91: 305-16. PMID 7095268 DOI: 10.1016/0012-1606(82)90037-9  0.555
1981 Connolly JL, Green SA, Greene LA. Pit formation and rapid changes in surface morphology of sympathetic neurons in response to nerve growth factor Journal of Cell Biology. 90: 176-180. PMID 7251673 DOI: 10.1083/JCB.90.1.176  0.334
1981 Taylor P, Rieger F, Shelanski M, Greene L. Cellular localization of the multiple molecular forms of acetylcholinesterase in cultured neuronal cells. Journal of Biological Chemistry. 256: 3827-3830. DOI: 10.1016/s0021-9258(19)69530-x  0.32
1980 Lee VM, Shelanski ML, Greene LA. Characterization of antisera raised against cultured rat sympathetic neurons. Neuroscience. 5: 2239-45. PMID 7007913 DOI: 10.1016/0306-4522(80)90140-2  0.369
1979 Kouvelas ED, Luckenbill-Edds L, LaVail JH, Greene LA. Effects of eye removal on receptors of alpha-bungarotoxin in the optic lobes of chick brain. Neuroscience Letters. 11: 99-102. PMID 431891 DOI: 10.1016/0304-3940(79)90063-6  0.58
1978 Greene LA. Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium Journal of Cell Biology. 78: 747-755. PMID 701359 DOI: 10.1083/Jcb.78.3.747  0.423
1978 Kouvelas ED, Dichter MA, Greene LA. Chick sympathetic neurons develop receptors for alpha-bungarotoxin in vitro, but the toxin does not block nicotinic receptors. Brain Research. 154: 83-93. PMID 698824 DOI: 10.1016/0006-8993(78)91053-3  0.69
1977 Greene LA. Quantitative in vitro studies on the nerve growth factor (NGF) requirement of neurons. I. Sympathetic neurons Developmental Biology. 58: 96-105. PMID 559605 DOI: 10.1016/0012-1606(77)90076-8  0.335
1977 Greene LA. Quantitative in vitro studies on the nerve growth factor (NGF) requirement of neurons. II. Sensory neurons Developmental Biology. 58: 106-113. PMID 559600 DOI: 10.1016/0012-1606(77)90077-X  0.356
1976 Kouvelas ED, Greene LA. The binding properties and regional ontogeny of receptors for alpha-bungarotoxin in chick brain. Brain Research. 113: 111-26. PMID 953721 DOI: 10.1016/0006-8993(76)90010-X  0.602
1975 Greene LA, Shain W, Chalazonitis A, Breakfield X, Minna J, Coon HG, Nirenberg M. Neuronal properties of hybrid neuroblastoma X sympathetic ganglion cells. Proceedings of the National Academy of Sciences of the United States of America. 72: 4923-7. PMID 1745 DOI: 10.1073/pnas.72.12.4923  0.55
1974 Chalazonitis A, Greene LA, Nirenberg M. Electrophysiological chracteristics of chick embryo sympathetic neurons in dissociated cell culture. Brain Research. 68: 235-52. PMID 4826897 DOI: 10.1016/0006-8993(74)90393-X  0.593
1973 Greene LA, Sytkowski AJ, Vogel Z, Nirenberg MW. -Bungarotoxin used as a probe for acetylcholine receptors of cultured neurones. Nature. 243: 163-6. PMID 4550035 DOI: 10.1038/243163a0  0.543
1971 Greene LA, Tomita JT, Varon S. Growth-stimulating activities of mouse submaxillary esteropeptidases on chick embryo fibroblasts in vitro. Experimental Cell Research. 64: 387-95. PMID 5100758 DOI: 10.1016/0014-4827(71)90092-9  0.484
1969 Greene LA, Shooter EM, Varon S. Subunit interaction and enzymatic activity of mouse 7S nerve growth factor. Biochemistry. 8: 3735-41. PMID 5820664 DOI: 10.1021/Bi00837A037  0.46
1969 Smith AP, Greene LA, Fish HR, Varon S, Shooter EM. Subunit equilibria of the 7S nerve growth factor protein. Biochemistry. 8: 4918-26. PMID 5365786 DOI: 10.1021/bi00840a040  0.462
1968 Greene LA, Shooter EM, Varon S. Enzymatic activities of mouse nerve growth factor and its subunits. Proceedings of the National Academy of Sciences of the United States of America. 60: 1383-8. PMID 5244746 DOI: 10.1073/Pnas.60.4.1383  0.466
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