65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Butler T, Goldberg JD, Galvin JE, Maloney T, Ravdin L, Glodzik L, de Leon MJ, Hochman T, Bowen RL, Atwood CS. Rationale, study design and implementation of the LUCINDA Trial: Leuprolide plus cholinesterase inhibition to reduce neurologic decline in Alzheimer's. Contemporary Clinical Trials. 106488. PMID 34166841 DOI: 10.1016/j.cct.2021.106488  0.595
2019 Butler T, Bowen R, Atwood CS. Septal hypertrophy and cell cycle re-entry in AD. Aging. PMID 30668543 DOI: 10.18632/aging.101777  0.552
2018 Smith MA, Bowen RL, Nguyen RQ, Perry G, Atwood CS, Rimm AA. Putative Gonadotropin Releasing Hormone Agonist Therapy and Dementia: An Application of Medicare Hospitalization Claims Data. Journal of Alzheimer's Disease : Jad. PMID 29782310 DOI: 10.3233/Jad-170847  0.741
2017 Atwood CS, Hayashi K, Meethal SV, Gonzales T, Bowen RL. Does the degree of endocrine dyscrasia post-reproduction dictate post-reproductive lifespan? Lessons from semelparous and iteroparous species. Geroscience. PMID 28271270 DOI: 10.1007/s11357-016-9955-5  0.548
2016 Bowen RL, Butler T, Atwood CS. Not All Androgen Deprivation Therapies Are Created Equal: Leuprolide and the Decreased Risk of Developing Alzheimer's Disease. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27298416 DOI: 10.1200/Jco.2015.66.3997  0.622
2015 Atwood CS, Bowen RL. A Unified Hypothesis of Early- and Late-Onset Alzheimer's Disease Pathogenesis. Journal of Alzheimer's Disease : Jad. 47: 33-47. PMID 26402752 DOI: 10.3233/Jad-143210  0.668
2015 Atwood CS, Bowen RL. The Endocrine Dyscrasia that Accompanies Menopause and Andropause Induces Aberrant Cell Cycle Signaling that Triggers Re-entry of Post-mitotic Neurons into the Cell Cycle, Neurodysfunction, Neurodegeneration and Cognitive Disease. Hormones and Behavior. PMID 26188949 DOI: 10.1016/J.Yhbeh.2015.06.021  0.696
2015 Bowen RL, Perry G, Xiong C, Smith MA, Atwood CS. A clinical study of lupron depot in the treatment of women with Alzheimer's disease: preservation of cognitive function in patients taking an acetylcholinesterase inhibitor and treated with high dose lupron over 48 weeks. Journal of Alzheimer's Disease : Jad. 44: 549-60. PMID 25310993 DOI: 10.3233/Jad-141626  0.663
2012 Clark I, Atwood C, Bowen R, Paz-Filho G, Vissel B. Tumor necrosis factor-induced cerebral insulin resistance in Alzheimer's disease links numerous treatment rationales. Pharmacological Reviews. 64: 1004-26. PMID 22966039 DOI: 10.1124/Pr.112.005850  0.608
2011 Atwood CS, Bowen RL. The reproductive-cell cycle theory of aging: an update. Experimental Gerontology. 46: 100-7. PMID 20851172 DOI: 10.1016/J.Exger.2010.09.007  0.573
2010 Gallego MJ, Porayette P, Kaltcheva MM, Bowen RL, Vadakkadath Meethal S, Atwood CS. The pregnancy hormones human chorionic gonadotropin and progesterone induce human embryonic stem cell proliferation and differentiation into neuroectodermal rosettes. Stem Cell Research & Therapy. 1: 28. PMID 20836886 DOI: 10.1186/Scrt28  0.593
2009 Porayette P, Gallego MJ, Kaltcheva MM, Bowen RL, Vadakkadath Meethal S, Atwood CS. Differential processing of amyloid-beta precursor protein directs human embryonic stem cell proliferation and differentiation into neuronal precursor cells. The Journal of Biological Chemistry. 284: 23806-17. PMID 19542221 DOI: 10.1074/Jbc.M109.026328  0.597
2009 Meethal SV, Liu T, Chan HW, Ginsburg E, Wilson AC, Gray DN, Bowen RL, Vonderhaar BK, Atwood CS. Identification of a regulatory loop for the synthesis of neurosteroids: a steroidogenic acute regulatory protein-dependent mechanism involving hypothalamic-pituitary-gonadal axis receptors. Journal of Neurochemistry. 110: 1014-27. PMID 19493163 DOI: 10.1111/J.1471-4159.2009.06192.X  0.629
2009 Simon DP, Vadakkadath Meethal S, Wilson AC, Gallego MJ, Weinecke SL, Bruce E, Lyons PF, Haasl RJ, Bowen RL, Atwood CS. Activin receptor signaling regulates prostatic epithelial cell adhesion and viability. Neoplasia (New York, N.Y.). 11: 365-76. PMID 19308291 DOI: 10.1593/Neo.81544  0.556
2008 Haasl RJ, Ahmadi MR, Meethal SV, Gleason CE, Johnson SC, Asthana S, Bowen RL, Atwood CS. A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E epsilon4 allele. Bmc Medical Genetics. 9: 37. PMID 18439297 DOI: 10.1186/1471-2350-9-37  0.627
2008 Casadesus G, Rolston RK, Webber KM, Atwood CS, Bowen RL, Perry G, Smith MA. Menopause, estrogen, and gonadotropins in Alzheimer's disease. Advances in Clinical Chemistry. 45: 139-53. PMID 18429496 DOI: 10.1016/S0065-2423(07)00006-6  0.76
2008 Wilson AC, Clemente L, Liu T, Bowen RL, Meethal SV, Atwood CS. Reproductive hormones regulate the selective permeability of the blood-brain barrier. Biochimica Et Biophysica Acta. 1782: 401-7. PMID 18381207 DOI: 10.1016/J.Bbadis.2008.02.011  0.632
2008 Atwood CS, Bowen RL. A multi-hit endocrine model of intrinsic adult-onset asthma. Ageing Research Reviews. 7: 114-25. PMID 18373959 DOI: 10.1016/J.Arr.2007.12.002  0.532
2008 Gallego MJ, Porayette P, Kaltcheva MM, Bowen RL, Meethal SV, Atwood CS. Trophoblastic hormones direct early human embryogenesis Nature Precedings. DOI: 10.1038/Npre.2008.2671.1  0.589
2008 Meethal SV, Chan H, Ginsburg E, Wilson AC, Bowen RL, Vonderhaar BK, Atwood CS. P4-220: Identification of a negative feedback loop in the brain for the regulation of neurosteroid synthesis: Implications for Alzheimer's disease Alzheimer's & Dementia. 4: T735-T736. DOI: 10.1016/J.Jalz.2008.05.2288  0.621
2008 Meethal SV, Ockuly JC, Porayette P, Gallego MJ, Haworth RA, Bowen RL, Atwood CS. P3-390: Gonadotropin-releasing hormone signaling in the aging brain: A recapitulation of its role in embryogenesis and its implications for Alzheimer's disease Alzheimer's & Dementia. 4: T635-T636. DOI: 10.1016/J.Jalz.2008.05.1960  0.667
2008 Porayette P, Gallego MJ, Kaltcheva MM, Bowen RL, Meethal SV, Atwood CS. P3-388: Differential processing of amyloid-β precursor protein directs the proliferation and neuronal differentiation of human embryonic stem cells Alzheimer's & Dementia. 4: T635-T635. DOI: 10.1016/J.Jalz.2008.05.1958  0.562
2007 Webber KM, Casadesus G, Bowen RL, Perry G, Smith MA. Evidence for the role of luteinizing hormone in Alzheimer disease. Endocrine, Metabolic & Immune Disorders Drug Targets. 7: 300-3. PMID 18220951 DOI: 10.2174/187153007782794326  0.69
2007 Wilson AC, Meethal SV, Bowen RL, Atwood CS. Leuprolide acetate: a drug of diverse clinical applications. Expert Opinion On Investigational Drugs. 16: 1851-63. PMID 17970643 DOI: 10.1517/13543784.16.11.1851  0.662
2007 Casadesus G, Milliken EL, Webber KM, Bowen RL, Lei Z, Rao CV, Perry G, Keri RA, Smith MA. Increases in luteinizing hormone are associated with declines in cognitive performance. Molecular and Cellular Endocrinology. 269: 107-11. PMID 17376589 DOI: 10.1016/J.Mce.2006.06.013  0.615
2007 Liu T, Wimalasena J, Bowen RL, Atwood CS. Luteinizing hormone receptor mediates neuronal pregnenolone production via up-regulation of steroidogenic acute regulatory protein expression. Journal of Neurochemistry. 100: 1329-39. PMID 17241129 DOI: 10.1111/J.1471-4159.2006.04307.X  0.638
2007 Atwood CS, Bowen RL. Metabolic clues regarding the enhanced performance of elite endurance athletes from orchiectomy-induced hormonal changes. Medical Hypotheses. 68: 735-49. PMID 17095167 DOI: 10.1016/J.Mehy.2006.08.037  0.571
2007 Webber KM, Casadesus G, Atwood CS, Bowen RL, Perry G, Smith MA. Gonadotropins: a cohesive gender-based etiology of Alzheimer disease. Molecular and Cellular Endocrinology. 260: 271-5. PMID 17052835 DOI: 10.1016/J.Mce.2006.01.018  0.768
2006 Wilson AC, Salamat MS, Haasl RJ, Roche KM, Karande A, Meethal SV, Terasawa E, Bowen RL, Atwood CS. Human neurons express type I GnRH receptor and respond to GnRH I by increasing luteinizing hormone expression. The Journal of Endocrinology. 191: 651-63. PMID 17170222 DOI: 10.1677/Joe.1.07047  0.629
2006 Casadesus G, Puig ER, Webber KM, Atwood CS, Escuer MC, Bowen RL, Perry G, Smith MA. Targeting gonadotropins: an alternative option for Alzheimer disease treatment. Journal of Biomedicine & Biotechnology. 2006: 39508. PMID 17047306 DOI: 10.1155/Jbb/2006/39508  0.757
2006 Webber KM, Stocco DM, Casadesus G, Bowen RL, Atwood CS, Previll LA, Harris PL, Zhu X, Perry G, Smith MA. Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer disease. Molecular Neurodegeneration. 1: 14. PMID 17018137 DOI: 10.1186/1750-1326-1-14  0.748
2006 Casadesus G, Garrett MR, Webber KM, Hartzler AW, Atwood CS, Perry G, Bowen RL, Smith MA. The estrogen myth: potential use of gonadotropin-releasing hormone agonists for the treatment of Alzheimer's disease. Drugs in R&D. 7: 187-93. PMID 16752944 DOI: 10.2165/00126839-200607030-00004  0.774
2006 Casadesus G, Webber KM, Atwood CS, Pappolla MA, Perry G, Bowen RL, Smith MA. Luteinizing hormone modulates cognition and amyloid-beta deposition in Alzheimer APP transgenic mice. Biochimica Et Biophysica Acta. 1762: 447-52. PMID 16503402 DOI: 10.1016/J.Bbadis.2006.01.008  0.745
2006 Webber KM, Casadesus G, Zhu X, Obrenovich ME, Atwood CS, Perry G, Bowen RL, Smith MA. The cell cycle and hormonal fluxes in Alzheimer disease: a novel therapeutic target. Current Pharmaceutical Design. 12: 691-7. PMID 16472159 DOI: 10.2174/138161206775474305  0.744
2006 Gregory CW, Atwood CS, Smith MA, Bowen RL. Antigonadotropins: a novel strategy to halt Alzheimer's disease progression. Current Pharmaceutical Design. 12: 685-90. PMID 16472158 DOI: 10.2174/138161206775474288  0.733
2006 Wilson AC, Salamat MS, Meethal SV, Smith MA, Terasawa E, Bowen RL, Atwood CS. Extrapituitary expression of luteinizing hormone by human neurons possessing GnRH receptor 1 Frontiers in Neuroendocrinology. 27: 87-88. DOI: 10.1016/J.Yfrne.2006.03.190  0.652
2006 Meethal SV, Gallego MJ, Haasl RJ, Petras SJ, Sgro JY, Bowen RL, Atwood CS. Identification of a gonadotropin-releasing hormone receptor homologue in Caenorhabditis elegans Frontiers in Neuroendocrinology. 27: 71. DOI: 10.1016/J.Yfrne.2006.03.149  0.592
2006 Webber KM, Casadesus G, Previll LA, Zhu X, Gregory C, Bowen R, Atwood CS, Perry G, Stocco DM, Smith MA. P1-369: Evidence of gonadotropin-induced steroidogenesis in Alzheimer's disease Alzheimer's & Dementia. 2: S206-S206. DOI: 10.1016/J.Jalz.2006.05.747  0.706
2006 Casadesus G, Webber KM, Atwood CS, Bowen RL, Perry G, Smith MA. P3-296: Luteinizing hormone mediates Alzheimer-type changes in neurons Alzheimer's & Dementia. 2: S462-S462. DOI: 10.1016/J.Jalz.2006.05.1565  0.705
2005 Meethal SV, Smith MA, Bowen RL, Atwood CS. The gonadotropin connection in Alzheimer's disease. Endocrine. 26: 317-26. PMID 16034187 DOI: 10.1385/Endo:26:3:317  0.755
2005 Webber KM, Casadesus G, Marlatt MW, Perry G, Hamlin CR, Atwood CS, Bowen RL, Smith MA. Estrogen bows to a new master: the role of gonadotropins in Alzheimer pathogenesis. Annals of the New York Academy of Sciences. 1052: 201-9. PMID 16024763 DOI: 10.1196/Annals.1347.020  0.76
2005 Ashford JW, Atwood CS, Blass JP, Bowen RL, Finch CE, Iqbal K, Joseph JA, Perry G. What is aging? What is its role in Alzheimer's disease? What can we do about it? Journal of Alzheimer's Disease : Jad. 7: 247-53; discussion 2. PMID 16006669 DOI: 10.3233/Jad-2005-7308  0.652
2005 Webber KM, Casadesus G, Perry G, Atwood CS, Bowen R, Smith MA. Gender differences in Alzheimer disease: the role of luteinizing hormone in disease pathogenesis. Alzheimer Disease and Associated Disorders. 19: 95-9. PMID 15942328 DOI: 10.1097/01.Wad.0000165512.90864.3F  0.762
2005 Atwood CS, Meethal SV, Liu T, Wilson AC, Gallego M, Smith MA, Bowen RL. Dysregulation of the hypothalamic-pituitary-gonadal axis with menopause and andropause promotes neurodegenerative senescence. Journal of Neuropathology and Experimental Neurology. 64: 93-103. PMID 15751223 DOI: 10.1093/Jnen/64.2.93  0.741
2005 Atwood CS, Smith MA, Bowen RL. Feedback on a feedback loop: the hypothalamic-pituitary-gonadal axis. Journal of Alzheimer's Disease : Jad. 7: 1-2. PMID 15750209 DOI: 10.3233/Jad-2005-7101  0.699
2005 Gregory CW, Bowen RL. Novel therapeutic strategies for Alzheimer's disease based on the forgotten reproductive hormones. Cellular and Molecular Life Sciences : Cmls. 62: 313-9. PMID 15723167 DOI: 10.1007/s00018-004-4386-y  0.454
2005 Casadesus G, Atwood CS, Zhu X, Hartzler AW, Webber KM, Perry G, Bowen RL, Smith MA. Evidence for the role of gonadotropin hormones in the development of Alzheimer disease. Cellular and Molecular Life Sciences : Cmls. 62: 293-8. PMID 15723165 DOI: 10.1007/S00018-004-4384-0  0.77
2005 Bowen RL, Martins RN, Gregory CW, Smith MA, Atwood CS. Dementia and testosterone levels in men. Jama. 293: 551; author reply 55. PMID 15687304 DOI: 10.1001/Jama.293.5.551-B  0.614
2004 Casadesus G, Zhu X, Atwood CS, Webber KM, Perry G, Bowen RL, Smith MA. Beyond estrogen: targeting gonadotropin hormones in the treatment of Alzheimer's disease. Current Drug Targets. Cns and Neurological Disorders. 3: 281-5. PMID 15379604 DOI: 10.2174/1568007043337265  0.785
2004 Bowen RL, Atwood CS. Living and dying for sex. A theory of aging based on the modulation of cell cycle signaling by reproductive hormones. Gerontology. 50: 265-90. PMID 15331856 DOI: 10.1159/000079125  0.605
2004 Bowen RL, Gregory CW. Sex hormones and ApoE4: beyond steroids. Journal of Alzheimer's Disease : Jad. 6: 229-30. PMID 15252936 DOI: 10.3233/Jad-2004-6303  0.455
2004 Webber KM, Bowen R, Casadesus G, Perry G, Atwood CS, Smith MA. Gonadotropins and Alzheimer's disease: the link between estrogen replacement therapy and neuroprotection. Acta Neurobiologiae Experimentalis. 64: 113-8. PMID 15190686  0.751
2004 Zhu X, McShea A, Harris PL, Raina AK, Castellani RJ, Funk JO, Shah S, Atwood C, Bowen R, Bowser R, Morelli L, Perry G, Smith MA. Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease. Journal of Neuroscience Research. 75: 698-703. PMID 14991845 DOI: 10.1002/Jnr.20028  0.714
2004 Bowen RL, Verdile G, Liu T, Parlow AF, Perry G, Smith MA, Martins RN, Atwood CS. Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition. The Journal of Biological Chemistry. 279: 20539-45. PMID 14871891 DOI: 10.1074/Jbc.M311993200  0.731
2004 Casadesus G, Webber KM, Ogawa O, Bowen RL, Atwood CS, Perry G, Smith MA. P1-369 Modulation of cognition and amyloid load in the aged SWAβPP transgenic mouse by luprolide acetate, a GNRH agonist: targeting luteinizing hormone as a novel treatment for AD Neurobiology of Aging. 25: S203. DOI: 10.1016/S0197-4580(04)80681-X  0.713
2004 Zhu X, McShea A, Harris PL, Raina AK, Castellani RJ, Funk J, Shah S, Atwood CS, Bowen R, Bowser R, Morelli L, Perry G, Smith MA. O2-04-07 Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1 associated regulator of cyclin B, in Alzheimer disease Neurobiology of Aging. 25: S40. DOI: 10.1016/S0197-4580(04)80133-7  0.681
2004 Atwood CS, Liu T, Smith MA, Martins RN, Bowen RL, Verdile G. O2-04-06 17β-Estradiol and luteinizing hormone modulate the expression of luteinizing hormone receptors in neuroblastoma cells Neurobiology of Aging. 25: S40. DOI: 10.1016/S0197-4580(04)80132-5  0.646
2004 Bowen R, Atwood CS, Perry G, Smith MA. Mechanisms Involved in Gender Differences in Alzheimer's Disease: The Role of Leuteinizing and Follicle Stimulating Hormones Principles of Gender-Specific Medicine. 2: 1234-1237. DOI: 10.1016/B978-012440905-7/50388-1  0.729
2003 Atwood CS, Barzilai N, Bowen RL, Brown-Borg HM, Jarrard DF, Fu VX, Heilbronn LK, Ingram DK, Ravussin E, Schwartz RS, Weindruch R. Pennington scientific symposium on mechanisms and retardation of aging. Experimental Gerontology. 38: 1217-26. PMID 14580876 DOI: 10.1016/J.Exger.2003.08.005  0.541
2003 Atwood CS, Bowen RL, Smith MA, Perry G. Cerebrovascular requirement for sealant, anti-coagulant and remodeling molecules that allow for the maintenance of vascular integrity and blood supply. Brain Research. Brain Research Reviews. 43: 164-78. PMID 14499467 DOI: 10.1016/S0165-0173(03)00206-6  0.646
2003 Smith MA, Perry G, Atwood CS, Bowen RL. Estrogen replacement and risk of Alzheimer disease. Jama. 289: 1100; author reply 1. PMID 12622570 DOI: 10.1001/Jama.289.9.1100-A  0.71
2002 Bowen RL, Smith MA, Harris PL, Kubat Z, Martins RN, Castellani RJ, Perry G, Atwood CS. Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology. Journal of Neuroscience Research. 70: 514-8. PMID 12391612 DOI: 10.1002/Jnr.10452  0.76
2001 Short RA, Bowen RL, O'Brien PC, Graff-Radford NR. Elevated gonadotropin levels in patients with Alzheimer disease. Mayo Clinic Proceedings. 76: 906-9. PMID 11560301 DOI: 10.4065/76.9.906  0.323
2001 Bowen RL. Sex hormones, amyloid protein, and Alzheimer disease. Jama. 286: 790-1. PMID 11497529 DOI: 10.1001/Jama.286.7.790  0.511
2000 Bowen RL, Isley JP, Atkinson RL. An association of elevated serum gonadotropin concentrations and Alzheimer disease? Journal of Neuroendocrinology. 12: 351-4. PMID 10718932 DOI: 10.1046/j.1365-2826.2000.00461.x  0.399
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