Lu-Yang Wang, Ph.D. - Publications

Affiliations: 
The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada 
Area:
Synaptic transmission

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Fekete A, Nakamura Y, Yang YM, Herlitze S, Mark MD, DiGregorio DA, Wang LY. Underpinning heterogeneity in synaptic transmission by presynaptic ensembles of distinct morphological modules. Nature Communications. 10: 826. PMID 30778063 DOI: 10.1038/s41467-019-08452-2  1
2018 Fekete A, Wang LY. Interneuron NMDA receptors change the gear of motor learning in the cerebellar machine. The Journal of Physiology. PMID 30552761 DOI: 10.1113/JP277376  1
2018 Yang YM, Arsenault J, Bah A, Krzeminski M, Fekete A, Chao OY, Pacey LK, Wang A, Forman-Kay J, Hampson DR, Wang LY. Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain. Molecular Psychiatry. PMID 30224722 DOI: 10.1038/s41380-018-0240-0  1
2017 Yang YM, Wang LY. Ageing brains attend a symphony with asynchronous transmitter release. The Journal of Physiology. 595: 613-614. PMID 28145009 DOI: 10.1113/JP273421  0.36
2016 Hou P, Xiao F, Liu H, Yuchi M, Zhang G, Wu Y, Wang W, Zeng W, Ding M, Cui J, Wu Z, Wang LY, Ding J. Extrapolating microdomain Ca(2+) dynamics using BK channels as a Ca(2+) sensor. Scientific Reports. 6: 17343. PMID 26776352 DOI: 10.1038/srep17343  1
2015 Yin XL, Liang M, Shi HB, Wang LY, Li CY, Yin SK. The role of gamma-aminobutyric acid/glycinergic synaptic transmission in mediating bilirubin-induced hyperexcitation in developing auditory neurons. Toxicology Letters. PMID 26476400 DOI: 10.1016/j.toxlet.2015.10.008  1
2014 Wang LY, Augustine GJ. Presynaptic nanodomains: a tale of two synapses. Frontiers in Cellular Neuroscience. 8: 455. PMID 25674049 DOI: 10.3389/fncel.2014.00455  1
2014 Wang LY, Tang JY, Liu J, Lu W, Yu YN, Chen BW, Wu HL, Su LY, Jing ZW, Hu SY, Liu XL, Yang XY, Li GX, Dong B, Wang DH, et al. Dynamic changes in phenotypic groups in patients with stable angina pectoris after treatment with Xinxuekang capsule: a randomized controlled trial. Current Vascular Pharmacology. PMID 25360840  0.36
2014 Yang YM, Wang W, Fedchyshyn MJ, Zhou Z, Ding J, Wang LY. Enhancing the fidelity of neurotransmission by activity-dependent facilitation of presynaptic potassium currents. Nature Communications. 5: 4564. PMID 25078759 DOI: 10.1038/ncomms5564  0.4
2014 David LS, Aitoubah J, Lesperance LS, Wang LY. Gene delivery in mouse auditory brainstem and hindbrain using in utero electroporation. Molecular Brain. 7: 51. PMID 25063346 DOI: 10.1186/s13041-014-0051-4  1
2014 Wang LY, Li G, Li Z, Lin L, Bi P. [Preliminary study on internal information of the measured tissue based on distributed multi-position scattering spectroscopy]. Guang Pu Xue Yu Guang Pu Fen Xi = Guang Pu. 34: 1026-30. PMID 25007622  0.8
2014 Grande G, Negandhi J, Harrison RV, Wang LY. Remodelling at the calyx of Held-MNTB synapse in mice developing with unilateral conductive hearing loss. The Journal of Physiology. 592: 1581-600. PMID 24469075 DOI: 10.1113/jphysiol.2013.268839  1
2013 Zhou H, Zeng C, Wang LY, Xie H, Zhou J, Diao P, Yao WX, Zhao X, Wei Y. Chemotherapy with or without gefitinib in patients with advanced non-small-cell lung cancer: a meta-analysis of 6,844 patients. Chinese Medical Journal. 126: 3348-55. PMID 24033963  0.36
2013 Wang LY, Murphy RR, Hanscom B, Li G, Millard SP, Petrie EC, Galasko DR, Sikkema C, Raskind MA, Wilkinson CW, Peskind ER. Cerebrospinal fluid norepinephrine and cognition in subjects across the adult age span. Neurobiology of Aging. 34: 2287-92. PMID 23639207 DOI: 10.1016/j.neurobiolaging.2013.04.007  0.8
2013 Wang LY, Summerhill K, Rodriguez-Canas C, Mather I, Patel P, Eiden M, Young S, Forouhi NG, Koulman A. Development and validation of a robust automated analysis of plasma phospholipid fatty acids for metabolic phenotyping of large epidemiological studies. Genome Medicine. 5: 39. PMID 23618465 DOI: 10.1186/gm443  0.36
2011 Grande G, Wang LY. Morphological and functional continuum underlying heterogeneity in the spiking fidelity at the calyx of Held synapse in vitro. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 13386-99. PMID 21940432 DOI: 10.1523/JNEUROSCI.0400-11.2011  1
2011 Yang YM, Aitoubah J, Lauer AM, Nuriya M, Takamiya K, Jia Z, May BJ, Huganir RL, Wang LY. GluA4 is indispensable for driving fast neurotransmission across a high-fidelity central synapse. The Journal of Physiology. 589: 4209-27. PMID 21690196 DOI: 10.1113/jphysiol.2011.208066  1
2011 Zhang B, Sun L, Yang YM, Huang HP, Zhu FP, Wang L, Zhang XY, Guo S, Zuo PL, Zhang CX, Ding JP, Wang LY, Zhou Z. Action potential bursts enhance transmitter release at a giant central synapse. The Journal of Physiology. 589: 2213-27. PMID 21486773 DOI: 10.1113/jphysiol.2010.200154  1
2010 Grande G, Wang LY. Early dating influences long-term synaptic partnerships. The Journal of Physiology. 588: 4339-40. PMID 21078599 DOI: 10.1113/jphysiol.2010.200089  1
2010 Xie G, Harrison J, Clapcote SJ, Huang Y, Zhang JY, Wang LY, Roder JC. A new Kv1.2 channelopathy underlying cerebellar ataxia. The Journal of Biological Chemistry. 285: 32160-73. PMID 20696761 DOI: 10.1074/jbc.M110.153676  1
2010 Yang YM, Fedchyshyn MJ, Grande G, Aitoubah J, Tsang CW, Xie H, Ackerley CA, Trimble WS, Wang LY. Septins regulate developmental switching from microdomain to nanodomain coupling of Ca(2+) influx to neurotransmitter release at a central synapse. Neuron. 67: 100-15. PMID 20624595 DOI: 10.1016/j.neuron.2010.06.003  1
2009 Wang LY, Fedchyshyn MJ, Yang YM. Action potential evoked transmitter release in central synapses: insights from the developing calyx of Held. Molecular Brain. 2: 36. PMID 19939269 DOI: 10.1186/1756-6606-2-36  0.4
2008 Wang LY, Neher E, Taschenberger H. Synaptic vesicles in mature calyx of Held synapses sense higher nanodomain calcium concentrations during action potential-evoked glutamate release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 14450-8. PMID 19118179 DOI: 10.1523/JNEUROSCI.4245-08.2008  1
2008 Tsang CW, Fedchyshyn M, Harrison J, Xie H, Xue J, Robinson PJ, Wang LY, Trimble WS. Superfluous role of mammalian septins 3 and 5 in neuronal development and synaptic transmission. Molecular and Cellular Biology. 28: 7012-29. PMID 18809578 DOI: 10.1128/MCB.00035-08  1
2007 Joshi I, Yang YM, Wang LY. Coincident activation of metabotropic glutamate receptors and NMDA receptors (NMDARs) downregulates perisynaptic/extrasynaptic NMDARs and enhances high-fidelity neurotransmission at the developing calyx of Held synapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9989-99. PMID 17855613 DOI: 10.1523/JNEUROSCI.2506-07.2007  0.36
2007 Fedchyshyn MJ, Wang LY. Activity-dependent changes in temporal components of neurotransmission at the juvenile mouse calyx of Held synapse. The Journal of Physiology. 581: 581-602. PMID 17347264 DOI: 10.1113/jphysiol.2007.129833  0.4
2006 Yang YM, Wang LY. Amplitude and kinetics of action potential-evoked Ca2+ current and its efficacy in triggering transmitter release at the developing calyx of Held synapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5698-708. PMID 16723526 DOI: 10.1523/JNEUROSCI.4889-05.2006  0.36
2006 Wang LC, Xiong W, Zheng J, Zhou Y, Zheng H, Zhang C, Zheng LH, Zhu XL, Xiong ZQ, Wang LY, Cheng HP, Zhou Z. The timing of endocytosis after activation of a G-protein-coupled receptor in a sensory neuron. Biophysical Journal. 90: 3590-8. PMID 16624826 DOI: 10.1529/biophysj.105.069476  1
2005 Renden R, Taschenberger H, Puente N, Rusakov DA, Duvoisin R, Wang LY, Lehre KP, von Gersdorff H. Glutamate transporter studies reveal the pruning of metabotropic glutamate receptors and absence of AMPA receptor desensitization at mature calyx of Held synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8482-97. PMID 16162930 DOI: 10.1523/JNEUROSCI.1848-05.2005  1
2005 Fedchyshyn MJ, Wang LY. Developmental transformation of the release modality at the calyx of Held synapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4131-40. PMID 15843616 DOI: 10.1523/JNEUROSCI.0350-05.2005  0.4
2003 Macica CM, von Hehn CA, Wang LY, Ho CS, Yokoyama S, Joho RH, Kaczmarek LK. Modulation of the kv3.1b potassium channel isoform adjusts the fidelity of the firing pattern of auditory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1133-41. PMID 12598601  1
1998 Joiner WJ, Tang MD, Wang LY, Dworetzky SI, Boissard CG, Gan L, Gribkoff VK, Kaczmarek LK. Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunits. Nature Neuroscience. 1: 462-9. PMID 10196543 DOI: 10.1038/2176  1
1998 Xiong ZG, Raouf R, Lu WY, Wang LY, Orser BA, Dudek EM, Browning MD, MacDonald JF. Regulation of N-methyl-D-aspartate receptor function by constitutively active protein kinase C. Molecular Pharmacology. 54: 1055-63. PMID 9855634  1
1998 Wang LY, Kaczmarek LK. High-frequency firing helps replenish the readily releasable pool of synaptic vesicles. Nature. 394: 384-8. PMID 9690475 DOI: 10.1038/28645  1
1998 Wang LY, Gan L, Forsythe ID, Kaczmarek LK. Contribution of the Kv3.1 potassium channel to high-frequency firing in mouse auditory neurones. The Journal of Physiology. 509: 183-94. PMID 9547392 DOI: 10.1111/j.1469-7793.1998.183bo.x  1
1998 Wang LY, Gan L, Perney TM, Schwartz I, Kaczmarek LK. Activation of Kv3.1 channels in neuronal spine-like structures may induce local potassium ion depletion. Proceedings of the National Academy of Sciences of the United States of America. 95: 1882-7. PMID 9465111 DOI: 10.1073/pnas.95.4.1882  1
1997 Joiner WJ, Wang LY, Tang MD, Kaczmarek LK. hSK4, a member of a novel subfamily of calcium-activated potassium channels. Proceedings of the National Academy of Sciences of the United States of America. 94: 11013-8. PMID 9380751 DOI: 10.1073/pnas.94.20.11013  1
1996 MacDonald JF, Browning MD, Wang LY. Long-term enhancement of excitability and the regulation of glutamate receptors by protein kinases. Epilepsy Research. Supplement. 12: 275-82. PMID 9302526  1
1996 Hahn SJ, Wang LY, Kaczmarek LK. Inhibition by nystatin of Kv1.3 channels expressed in Chinese hamster ovary cells. Neuropharmacology. 35: 895-901. PMID 8938720 DOI: 10.1016/0028-3908(96)00094-9  1
1995 Orser BA, Bertlik M, Wang LY, MacDonald JF. Inhibition by propofol (2,6 di-isopropylphenol) of the N-methyl-D-aspartate subtype of glutamate receptor in cultured hippocampal neurones. British Journal of Pharmacology. 116: 1761-8. PMID 8528557  1
1995 Wang LY, MacDonald JF. Modulation by magnesium of the affinity of NMDA receptors for glycine in murine hippocampal neurones. The Journal of Physiology. 486: 83-95. PMID 7562646  1
1995 Kanemasa T, Gan L, Perney TM, Wang LY, Kaczmarek LK. Electrophysiological and pharmacological characterization of a mammalian Shaw channel expressed in NIH 3T3 fibroblasts. Journal of Neurophysiology. 74: 207-17. PMID 7472324  1
1994 Taverna FA, Wang LY, MacDonald JF, Hampson DR. A transmembrane model for an ionotropic glutamate receptor predicted on the basis of the location of asparagine-linked oligosaccharides. The Journal of Biological Chemistry. 269: 14159-64. PMID 8188697  1
1994 Wang LY, Orser BA, Brautigan DL, MacDonald JF. Regulation of NMDA receptors in cultured hippocampal neurons by protein phosphatases 1 and 2A. Nature. 369: 230-2. PMID 8183343 DOI: 10.1038/369230a0  1
1994 Taverna FA, Cameron BR, Hampson DL, Wang LY, MacDonald JF. Sensitivity of AMPA receptors to pentobarbital. European Journal of Pharmacology. 267: R3-5. PMID 8088363 DOI: 10.1016/0922-4106(94)90161-9  1
1994 Wang LY, Dudek EM, Browning MD, MacDonald JF. Modulation of AMPA/kainate receptors in cultured murine hippocampal neurones by protein kinase C. The Journal of Physiology. 475: 431-7. PMID 8006827  1
1994 Orser BA, Wang LY, Pennefather PS, MacDonald JF. Propofol modulates activation and desensitization of GABAA receptors in cultured murine hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 7747-60. PMID 7996209  1
1994 Ross SM, Taverna FA, Pickering DS, Wang LY, MacDonald JF, Pennefather PS, Hampson DR. Expression of functional metabotropic and ionotropic glutamate receptors in baculovirus-infected insect cells. Neuroscience Letters. 173: 139-42. PMID 7936400 DOI: 10.1016/0304-3940(94)90168-6  1
1994 Tymianski M, Wang LY, MacDonald JF. Alteration of neuronal calcium homeostasis and excitotoxic vulnerability by chronic depolarization. Brain Research. 648: 291-5. PMID 7922543 DOI: 10.1016/0006-8993(94)91129-0  1
1993 Wang LY, Taverna FA, Huang XP, MacDonald JF, Hampson DR. Phosphorylation and modulation of a kainate receptor (GluR6) by cAMP-dependent protein kinase. Science (New York, N.Y.). 259: 1173-5. PMID 8382377  1
1991 Wang LY, Salter MW, MacDonald JF. Regulation of kainate receptors by cAMP-dependent protein kinase and phosphatases. Science (New York, N.Y.). 253: 1132-5. PMID 1653455  1
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