John Carling Roder, Ph.D. - Publications

Affiliations: 
Samuel Lunenfeld Research Institute Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Neuobiology
Website:
http://www.mshri.on.ca/roder/

128 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ng E, Georgiou J, Avila A, Trought K, Mun HS, Hodgson M, Servinis P, Roder JC, Collingridge GL, Wong AH. Mice lacking Neuronal Calcium Sensor-1 show social and cognitive deficits. Behavioural Brain Research. 112420. PMID 31821787 DOI: 10.1016/J.Bbr.2019.112420  0.568
2017 McGirr A, Lipina TV, Mun HS, Georgiou J, Al-Amri AH, Ng E, Zhai D, Elliott C, Cameron RT, Mullins JG, Liu F, Baillie GS, Clapcote SJ, Roder JC. Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis and Facilitates Memory Acquisition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 42: 1178. PMID 28294143 DOI: 10.1038/npp.2016.263  0.687
2016 Kirshenbaum GS, Idris NF, Dachtler J, Roder JC, Clapcote SJ. Deficits in social behavioral tests in a mouse model of alternating hemiplegia of childhood. Journal of Neurogenetics. 30: 42-9. PMID 27276195 DOI: 10.1080/01677063.2016.1182525  0.638
2015 Mesbah-Oskui L, Georgiou J, Roder JC. Hippocampal place cell and inhibitory neuron activity in disrupted-in-schizophrenia-1 mutant mice: implications for working memory deficits. Npj Schizophrenia. 1: 15011. PMID 27336029 DOI: 10.1038/npjschz.2015.11  0.567
2015 Mesbah-Oskui L, Georgiou J, Roder JC. Hippocampal place cell and inhibitory neuron activity in Disrupted-in-schizophrenia-1 mutant mice: implications for working memory deficits. Npj Schizophrenia. 1. PMID 27280123  0.567
2015 Mun HS, Saab BJ, Ng E, McGirr A, Lipina TV, Gondo Y, Georgiou J, Roder JC. Self-directed exploration provides a Ncs1-dependent learning bonus. Scientific Reports. 5: 17697. PMID 26639399 DOI: 10.1038/Srep17697  0.567
2015 Kirshenbaum GS, Dachtler J, Roder JC, Clapcote SJ. Characterization of Cognitive Deficits in Mice With an Alternating Hemiplegia-Linked Mutation. Behavioral Neuroscience. PMID 26501181 DOI: 10.1037/Bne0000097  0.657
2015 Kirshenbaum GS, Dachtler J, Roder JC, Clapcote SJ. Transgenic rescue of phenotypic deficits in a mouse model of alternating hemiplegia of childhood. Neurogenetics. PMID 26463346 DOI: 10.1007/S10048-015-0461-1  0.668
2015 McGirr A, Lipina TV, Mun HS, Georgiou J, Al-Amri AH, Ng E, Zhai D, Elliott C, Cameron RT, Mullins JG, Liu F, Baillie GS, Clapcote SJ, Roder JC. Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis and Facilitates Memory Acquisition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26272049 DOI: 10.1038/Npp.2015.240  0.762
2015 Rivera-Fuentes P, Wrobel AT, Zastrow ML, Khan M, Georgiou J, Luyben TT, Roder JC, Okamoto K, Lippard SJ. A Far-Red Emitting Probe for Unambiguous Detection of Mobile Zinc in Acidic Vesicles and Deep Tissue. Chemical Science (Royal Society of Chemistry : 2010). 6: 1944-1948. PMID 25815162 DOI: 10.1039/C4Sc03388D  0.531
2014 Khan M, Goldsmith CR, Huang Z, Georgiou J, Luyben TT, Roder JC, Lippard SJ, Okamoto K. Two-photon imaging of Zn2+ dynamics in mossy fiber boutons of adult hippocampal slices. Proceedings of the National Academy of Sciences of the United States of America. 111: 6786-91. PMID 24757053 DOI: 10.1073/Pnas.1405154111  0.552
2014 Porteous DJ, Thomson PA, Millar JK, Evans KL, Hennah W, Soares DC, McCarthy S, McCombie WR, Clapcote SJ, Korth C, Brandon NJ, Sawa A, Kamiya A, Roder JC, Lawrie SM, et al. DISC1 as a genetic risk factor for schizophrenia and related major mental illness: response to Sullivan. Molecular Psychiatry. 19: 141-3. PMID 24457522 DOI: 10.1038/Mp.2013.160  0.594
2013 Li S, Nai Q, Lipina TV, Roder JC, Liu F. α7nAchR/NMDAR coupling affects NMDAR function and object recognition. Molecular Brain. 6: 58. PMID 24360204 DOI: 10.1186/1756-6606-6-58  0.335
2013 Lee FH, Zai CC, Cordes SP, Roder JC, Wong AH. Abnormal interneuron development in disrupted-in-schizophrenia-1 L100P mutant mice. Molecular Brain. 6: 20. PMID 23631734 DOI: 10.1186/1756-6606-6-20  0.348
2013 Kirshenbaum GS, Dawson N, Mullins JG, Johnston TH, Drinkhill MJ, Edwards IJ, Fox SH, Pratt JA, Brotchie JM, Roder JC, Clapcote SJ. Alternating hemiplegia of childhood-related neural and behavioural phenotypes in Na+,K+-ATPase α3 missense mutant mice. Plos One. 8: e60141. PMID 23527305 DOI: 10.1371/Journal.Pone.0060141  0.676
2013 Lipina TV, Fletcher PJ, Lee FH, Wong AH, Roder JC. Disrupted-in-schizophrenia-1 Gln31Leu polymorphism results in social anhedonia associated with monoaminergic imbalance and reduction of CREB and β-arrestin-1,2 in the nucleus accumbens in a mouse model of depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 423-36. PMID 23011268 DOI: 10.1038/Npp.2012.197  0.313
2013 Lipina TV, Palomo V, Gil C, Martinez A, Roder JC. Dual inhibitor of PDE7 and GSK-3-VP1.15 acts as antipsychotic and cognitive enhancer in C57BL/6J mice. Neuropharmacology. 64: 205-14. PMID 22749842 DOI: 10.1016/J.Neuropharm.2012.06.032  0.356
2012 Lipina TV, Haque FN, McGirr A, Boutros PC, Berger T, Mak TW, Roder JC, Wong AH. Prophylactic valproic acid treatment prevents schizophrenia-related behaviour in Disc1-L100P mutant mice. Plos One. 7: e51562. PMID 23272119 DOI: 10.1371/Journal.Pone.0051562  0.35
2012 Kirshenbaum GS, Clapcote SJ, Petersen J, Vilsen B, Ralph MR, Roder JC. Genetic suppression of agrin reduces mania-like behavior in Na+ , K+ -ATPase α3 mutant mice. Genes, Brain, and Behavior. 11: 436-43. PMID 22520507 DOI: 10.1111/J.1601-183X.2012.00800.X  0.684
2012 Thompson M, Marecki JC, Marinesco S, Labrie V, Roder JC, Barger SW, Crow JP. Paradoxical roles of serine racemase and D-serine in the G93A mSOD1 mouse model of amyotrophic lateral sclerosis. Journal of Neurochemistry. 120: 598-610. PMID 22117694 DOI: 10.1111/J.1471-4159.2011.07601.X  0.305
2012 Lipina TV, Wang M, Liu F, Roder JC. Synergistic interactions between PDE4B and GSK-3: DISC1 mutant mice. Neuropharmacology. 62: 1252-62. PMID 21376063 DOI: 10.1016/J.Neuropharm.2011.02.020  0.381
2012 Labrie V, Wong AH, Roder JC. Contributions of the D-serine pathway to schizophrenia. Neuropharmacology. 62: 1484-503. PMID 21295046 DOI: 10.1016/J.Neuropharm.2011.01.030  0.301
2012 Kirshenbaum GS, Clapcote SJ, Duffy S, Burgess CR, Petersen J, Jarowek KJ, Yücel YH, Cortez MA, Snead OC, Vilsen B, Peever JH, Ralph MR, Roder JC. Mania-like behavior induced by genetic dysfunction of the neuron-specific Na +,K +-ATPase α3 sodium pump (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 44, (18144-18149) DOI: 10.1073/pnas.1108416108) Proceedings of the National Academy of Sciences of the United States of America. 109: 2174. DOI: 10.1073/pnas.1121504109  0.607
2012 Brown SM, Clapcote SJ, Millar JK, Torrance HS, Anderson SM, Walker R, Rampino A, Roder JC, Thomson PA, Porteous DJ, Evans KL. Synaptic modulators Nrxn1 and Nrxn3 are disregulated in a Disc1 mouse model of schizophrenia (Molecular Psychiatry (2011) 16, (585-587) DOI: 10.1038/mp.2010.134) Molecular Psychiatry. 17: 469. DOI: 10.1038/mp.2011.27  0.623
2012 Lee FH, Zai CC, Cordes SP, Roder JC, Wong AH. Poster #123 INTERNEURON DEVELOPMENT IN DISC1 MUTANT MICE Schizophrenia Research. 136: S324-S325. DOI: 10.1016/S0920-9964(12)70956-8  0.375
2011 Kirshenbaum GS, Clapcote SJ, Duffy S, Burgess CR, Petersen J, Jarowek KJ, Yücel YH, Cortez MA, Snead OC, Vilsen B, Peever JH, Ralph MR, Roder JC. Mania-like behavior induced by genetic dysfunction of the neuron-specific Na+,K+-ATPase α3 sodium pump. Proceedings of the National Academy of Sciences of the United States of America. 108: 18144-9. PMID 22025725 DOI: 10.1073/Pnas.1108416108  0.786
2011 Lipina TV, Rasquinha R, Roder JC. Parametric and pharmacological modulations of latent inhibition in mouse inbred strains. Pharmacology, Biochemistry, and Behavior. 100: 244-52. PMID 21903127 DOI: 10.1016/J.Pbb.2011.08.023  0.776
2011 Lazar NL, Singh S, Paton T, Clapcote SJ, Gondo Y, Fukumura R, Roder JC, Cain DP. Missense mutation of the reticulon-4 receptor alters spatial memory and social interaction in mice. Behavioural Brain Research. 224: 73-9. PMID 21645550 DOI: 10.1016/J.Bbr.2011.05.020  0.677
2011 Lee FH, Kaidanovich-Beilin O, Roder JC, Woodgett JR, Wong AH. Genetic inactivation of GSK3α rescues spine deficits in Disc1-L100P mutant mice. Schizophrenia Research. 129: 74-9. PMID 21498050 DOI: 10.1016/J.Schres.2011.03.032  0.374
2011 Bouhours M, Po MD, Gao S, Hung W, Li H, Georgiou J, Roder JC, Zhen M. A co-operative regulation of neuronal excitability by UNC-7 innexin and NCA/NALCN leak channel. Molecular Brain. 4: 16. PMID 21489288 DOI: 10.1186/1756-6606-4-16  0.557
2011 Kirshenbaum GS, Saltzman K, Rose B, Petersen J, Vilsen B, Roder JC. Decreased neuronal Na+, K+ -ATPase activity in Atp1a3 heterozygous mice increases susceptibility to depression-like endophenotypes by chronic variable stress. Genes, Brain, and Behavior. 10: 542-50. PMID 21418141 DOI: 10.1111/J.1601-183X.2011.00691.X  0.315
2011 Jin F, Dong B, Georgiou J, Jiang Q, Zhang J, Bharioke A, Qiu F, Lommel S, Feltri ML, Wrabetz L, Roder JC, Eyer J, Chen X, Peterson AC, Siminovitch KA. N-WASp is required for Schwann cell cytoskeletal dynamics, normal myelin gene expression and peripheral nerve myelination. Development (Cambridge, England). 138: 1329-37. PMID 21385763 DOI: 10.1242/Dev.058677  0.551
2011 Lee FH, Fadel MP, Preston-Maher K, Cordes SP, Clapcote SJ, Price DJ, Roder JC, Wong AH. Disc1 point mutations in mice affect development of the cerebral cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 3197-206. PMID 21368031 DOI: 10.1523/Jneurosci.4219-10.2011  0.674
2011 Brown SM, Clapcote SJ, Millar JK, Torrance HS, Anderson SM, Walker R, Rampino A, Roder JC, Thomson PA, Porteous DJ, Evans KL. Synaptic modulators Nrxn1 and Nrxn3 are disregulated in a Disc1 mouse model of schizophrenia. Molecular Psychiatry. 16: 585-7. PMID 21321563 DOI: 10.1038/Mp.2010.134  0.651
2011 Lipina TV, Kaidanovich-Beilin O, Patel S, Wang M, Clapcote SJ, Liu F, Woodgett JR, Roder JC. Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3. Synapse (New York, N.Y.). 65: 234-48. PMID 20687111 DOI: 10.1002/Syn.20839  0.667
2010 Saab BJ, Maclean AJ, Kanisek M, Zurek AA, Martin LJ, Roder JC, Orser BA. Short-term memory impairment after isoflurane in mice is prevented by the α5 γ-aminobutyric acid type A receptor inverse agonist L-655,708. Anesthesiology. 113: 1061-71. PMID 20966663 DOI: 10.1097/Aln.0B013E3181F56228  0.321
2010 Yu T, Liu C, Belichenko P, Clapcote SJ, Li S, Pao A, Kleschevnikov A, Bechard AR, Asrar S, Chen R, Fan N, Zhou Z, Jia Z, Chen C, Roder JC, et al. Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice. Brain Research. 1366: 162-71. PMID 20932954 DOI: 10.1016/J.Brainres.2010.09.107  0.668
2010 Xie G, Harrison J, Clapcote SJ, Huang Y, Zhang JY, Wang LY, Roder JC. A new Kv1.2 channelopathy underlying cerebellar ataxia. The Journal of Biological Chemistry. 285: 32160-73. PMID 20696761 DOI: 10.1074/Jbc.M110.153676  0.678
2010 Sinai L, Duffy S, Roder JC. Src inhibition reduces NR2B surface expression and synaptic plasticity in the amygdala. Learning & Memory (Cold Spring Harbor, N.Y.). 17: 364-71. PMID 20660101 DOI: 10.1101/Lm.1765710  0.331
2010 Lipina TV, Niwa M, Jaaro-Peled H, Fletcher PJ, Seeman P, Sawa A, Roder JC. Enhanced dopamine function in DISC1-L100P mutant mice: implications for schizophrenia. Genes, Brain, and Behavior. 9: 777-89. PMID 20618446 DOI: 10.1111/J.1601-183X.2010.00615.X  0.339
2010 Yu T, Clapcote SJ, Li Z, Liu C, Pao A, Bechard AR, Carattini-Rivera S, Matsui S, Roder JC, Baldini A, Mobley WC, Bradley A, Yu YE. Deficiencies in the region syntenic to human 21q22.3 cause cognitive deficits in mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 21: 258-67. PMID 20512340 DOI: 10.1007/S00335-010-9262-X  0.677
2010 Yu T, Li Z, Jia Z, Clapcote SJ, Liu C, Li S, Asrar S, Pao A, Chen R, Fan N, Carattini-Rivera S, Bechard AR, Spring S, Henkelman RM, Stoica G, ... ... Roder JC, et al. A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions. Human Molecular Genetics. 19: 2780-91. PMID 20442137 DOI: 10.1093/Hmg/Ddq179  0.657
2010 Martin LJ, Zurek AA, MacDonald JF, Roder JC, Jackson MF, Orser BA. Alpha5GABAA receptor activity sets the threshold for long-term potentiation and constrains hippocampus-dependent memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5269-82. PMID 20392949 DOI: 10.1523/Jneurosci.4209-09.2010  0.337
2010 Labrie V, Wang W, Barger SW, Baker GB, Roder JC. Genetic loss of D-amino acid oxidase activity reverses schizophrenia-like phenotypes in mice. Genes, Brain, and Behavior. 9: 11-25. PMID 19751394 DOI: 10.1111/J.1601-183X.2009.00529.X  0.406
2010 Labrie V, Roder JC. The involvement of the NMDA receptor D-serine/glycine site in the pathophysiology and treatment of schizophrenia. Neuroscience and Biobehavioral Reviews. 34: 351-72. PMID 19695284 DOI: 10.1016/J.Neubiorev.2009.08.002  0.315
2009 Kaidanovich-Beilin O, Lipina TV, Takao K, van Eede M, Hattori S, Laliberté C, Khan M, Okamoto K, Chambers JW, Fletcher PJ, MacAulay K, Doble BW, Henkelman M, Miyakawa T, Roder J, et al. Abnormalities in brain structure and behavior in GSK-3alpha mutant mice. Molecular Brain. 2: 35. PMID 19925672 DOI: 10.1186/1756-6606-2-35  0.368
2009 Saab BJ, Georgiou J, Nath A, Lee FJ, Wang M, Michalon A, Liu F, Mansuy IM, Roder JC. NCS-1 in the dentate gyrus promotes exploration, synaptic plasticity, and rapid acquisition of spatial memory. Neuron. 63: 643-56. PMID 19755107 DOI: 10.1016/J.Neuron.2009.08.014  0.596
2009 Clapcote SJ, Duffy S, Xie G, Kirshenbaum G, Bechard AR, Rodacker Schack V, Petersen J, Sinai L, Saab BJ, Lerch JP, Minassian BA, Ackerley CA, Sled JG, Cortez MA, Henderson JT, ... ... Roder JC, et al. Mutation I810N in the alpha3 isoform of Na+,K+-ATPase causes impairments in the sodium pump and hyperexcitability in the CNS. Proceedings of the National Academy of Sciences of the United States of America. 106: 14085-90. PMID 19666602 DOI: 10.1073/Pnas.0904817106  0.66
2009 Labrie V, Fukumura R, Rastogi A, Fick LJ, Wang W, Boutros PC, Kennedy JL, Semeralul MO, Lee FH, Baker GB, Belsham DD, Barger SW, Gondo Y, Wong AH, Roder JC. Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model. Human Molecular Genetics. 18: 3227-43. PMID 19483194 DOI: 10.1093/Hmg/Ddp261  0.351
2009 Ng D, Pitcher GM, Szilard RK, Sertié A, Kanisek M, Clapcote SJ, Lipina T, Kalia LV, Joo D, McKerlie C, Cortez M, Roder JC, Salter MW, McInnes RR. Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning. Plos Biology. 7: e41. PMID 19243221 DOI: 10.1371/Journal.Pbio.1000041  0.687
2009 Labrie V, Duffy S, Wang W, Barger SW, Baker GB, Roder JC. Genetic inactivation of D-amino acid oxidase enhances extinction and reversal learning in mice. Learning & Memory (Cold Spring Harbor, N.Y.). 16: 28-37. PMID 19117914 DOI: 10.1101/Lm.1112209  0.375
2009 Labrie V, Clapcote SJ, Roder JC. Mutant mice with reduced NMDA-NR1 glycine affinity or lack of D-amino acid oxidase function exhibit altered anxiety-like behaviors. Pharmacology, Biochemistry, and Behavior. 91: 610-20. PMID 18940194 DOI: 10.1016/J.Pbb.2008.09.016  0.686
2008 Labrie V, Lipina T, Roder JC. Mice with reduced NMDA receptor glycine affinity model some of the negative and cognitive symptoms of schizophrenia. Psychopharmacology. 200: 217-30. PMID 18597079 DOI: 10.1007/S00213-008-1196-6  0.386
2008 Wang W, Bouhours M, Gracheva EO, Liao EH, Xu K, Sengar AS, Xin X, Roder J, Boone C, Richmond JE, Zhen M, Egan SE. ITSN-1 controls vesicle recycling at the neuromuscular junction and functions in parallel with DAB-1. Traffic (Copenhagen, Denmark). 9: 742-54. PMID 18298590 DOI: 10.1111/J.1600-0854.2008.00712.X  0.322
2008 Soleimani L, Roder JC, Dennis JW, Lipina T. Beta N-acetylglucosaminyltransferase V (Mgat5) deficiency reduces the depression-like phenotype in mice. Genes, Brain, and Behavior. 7: 334-43. PMID 17883406 DOI: 10.1111/J.1601-183X.2007.00358.X  0.352
2008 Young EJ, Lipina T, Tam E, Mandel A, Clapcote SJ, Bechard AR, Chambers J, Mount HT, Fletcher PJ, Roder JC, Osborne LR. Reduced fear and aggression and altered serotonin metabolism in Gtf2ird1-targeted mice. Genes, Brain, and Behavior. 7: 224-34. PMID 17680805 DOI: 10.1111/J.1601-183X.2007.00343.X  0.672
2008 Duffy S, Labrie V, Roder JC. D-serine augments NMDA-NR2B receptor-dependent hippocampal long-term depression and spatial reversal learning. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1004-18. PMID 17625504 DOI: 10.1038/Sj.Npp.1301486  0.35
2007 Fawcett JP, Georgiou J, Ruston J, Bladt F, Sherman A, Warner N, Saab BJ, Scott R, Roder JC, Pawson T. Nck adaptor proteins control the organization of neuronal circuits important for walking. Proceedings of the National Academy of Sciences of the United States of America. 104: 20973-8. PMID 18093944 DOI: 10.1073/Pnas.0710316105  0.566
2007 Parker JA, Metzler M, Georgiou J, Mage M, Roder JC, Rose AM, Hayden MR, Néri C. Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11056-64. PMID 17928447 DOI: 10.1523/Jneurosci.1941-07.2007  0.601
2007 Ishizuka K, Chen J, Taya S, Li W, Millar JK, Xu Y, Clapcote SJ, Hookway C, Morita M, Kamiya A, Tomoda T, Lipska BK, Roder JC, Pletnikov M, Porteous D, et al. Evidence that many of the DISC1 isoforms in C57BL/6J mice are also expressed in 129S6/SvEv mice. Molecular Psychiatry. 12: 897-9. PMID 17895924 DOI: 10.1038/Sj.Mp.4002024  0.679
2007 Millar JK, Mackie S, Clapcote SJ, Murdoch H, Pickard BS, Christie S, Muir WJ, Blackwood DH, Roder JC, Houslay MD, Porteous DJ. Disrupted in schizophrenia 1 and phosphodiesterase 4B: towards an understanding of psychiatric illness. The Journal of Physiology. 584: 401-5. PMID 17823207 DOI: 10.1113/Jphysiol.2007.140210  0.661
2007 Clapcote SJ, Lipina TV, Millar JK, Mackie S, Christie S, Ogawa F, Lerch JP, Trimble K, Uchiyama M, Sakuraba Y, Kaneda H, Shiroishi T, Houslay MD, Henkelman RM, Sled JG, ... ... Roder JC, et al. Behavioral phenotypes of Disc1 missense mutations in mice. Neuron. 54: 387-402. PMID 17481393 DOI: 10.1016/J.Neuron.2007.04.015  0.689
2007 Xie G, Clapcote SJ, Nieman BJ, Tallerico T, Huang Y, Vukobradovic I, Cordes SP, Osborne LR, Rossant J, Sled JG, Henderson JT, Roder JC. Forward genetic screen of mouse reveals dominant missense mutation in the P/Q-type voltage-dependent calcium channel, CACNA1A. Genes, Brain, and Behavior. 6: 717-27. PMID 17376154 DOI: 10.1111/J.1601-183X.2007.00302.X  0.665
2007 Metzler M, Gan L, Wong TP, Liu L, Helm J, Liu L, Georgiou J, Wang Y, Bissada N, Cheng K, Roder JC, Wang YT, Hayden MR. NMDA receptor function and NMDA receptor-dependent phosphorylation of huntingtin is altered by the endocytic protein HIP1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2298-308. PMID 17329427 DOI: 10.1523/Jneurosci.5175-06.2007  0.586
2006 Abramow-Newerly W, Lipina T, Abramow-Newerly M, Kim D, Bechard AR, Xie G, Clapcote SJ, Roder JC. Methods to rapidly and accurately screen a large number of ENU mutagenized mice for abnormal motor phenotypes. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 7: 112-8. PMID 16753976 DOI: 10.1080/14660820500443000  0.659
2006 Clapcote SJ, Roder JC. Deletion polymorphism of Disc1 is common to all 129 mouse substrains: implications for gene-targeting studies of brain function. Genetics. 173: 2407-10. PMID 16751659 DOI: 10.1534/Genetics.106.060749  0.668
2006 Bock NA, Kovacevic N, Lipina TV, Roder JC, Ackerman SL, Henkelman RM. In vivo magnetic resonance imaging and semiautomated image analysis extend the brain phenotype for cdf/cdf mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4455-9. PMID 16641223 DOI: 10.1523/Jneurosci.5438-05.2006  0.314
2006 Cheng VY, Martin LJ, Elliott EM, Kim JH, Mount HT, Taverna FA, Roder JC, Macdonald JF, Bhambri A, Collinson N, Wafford KA, Orser BA. Alpha5GABAA receptors mediate the amnestic but not sedative-hypnotic effects of the general anesthetic etomidate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3713-20. PMID 16597725 DOI: 10.1523/Jneurosci.5024-05.2006  0.37
2006 Snead OC, Clapcote SJ, Roder JC, Boulianne GL. Novel strategies for the development of animal models of refractory epilepsy. Advances in Neurology. 97: 155-71. PMID 16383125  0.579
2005 Holahan MR, Taverna FA, Emrich SM, Louis M, Muller RU, Roder JC, McDonald RJ. Impairment in long-term retention but not short-term performance on a water maze reversal task following hippocampal or mediodorsal striatal N-methyl-D-aspartate receptor blockade. Behavioral Neuroscience. 119: 1563-71. PMID 16420159 DOI: 10.1037/0735-7044.119.6.1563  0.528
2005 Macdonald DS, Weerapura M, Beazely MA, Martin L, Czerwinski W, Roder JC, Orser BA, MacDonald JF. Modulation of NMDA receptors by pituitary adenylate cyclase activating peptide in CA1 neurons requires G alpha q, protein kinase C, and activation of Src. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11374-84. PMID 16339032 DOI: 10.1523/Jneurosci.3871-05.2005  0.318
2005 Clapcote SJ, Lazar NL, Bechard AR, Roder JC. Effects of the rd1 mutation and host strain on hippocampal learning in mice. Behavior Genetics. 35: 591-601. PMID 16184487 DOI: 10.1007/S10519-005-5634-5  0.667
2005 Clapcote SJ, Lazar NL, Bechard AR, Wood GA, Roder JC. NIH Swiss and Black Swiss mice have retinal degeneration and performance deficits in cognitive tests. Comparative Medicine. 55: 310-6. PMID 16158906  0.649
2005 Clapcote SJ, Roder JC. Simplex PCR assay for sex determination in mice. Biotechniques. 38: 702, 704, 706. PMID 15945368 DOI: 10.2144/05385Bm05  0.661
2005 Taverna FA, Georgiou J, McDonald RJ, Hong NS, Kraev A, Salter MW, Takeshima H, Muller RU, Roder JC. Defective place cell activity in nociceptin receptor knockout mice with elevated NMDA receptor-dependent long-term potentiation. The Journal of Physiology. 565: 579-91. PMID 15774528 DOI: 10.1113/Jphysiol.2004.081802  0.699
2005 Lipina T, Labrie V, Weiner I, Roder J. Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia. Psychopharmacology. 179: 54-67. PMID 15759151 DOI: 10.1007/S00213-005-2210-X  0.339
2004 Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, ... ... Roder J, et al. The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nature Genetics. 36: 1133-7. PMID 15514660 DOI: 10.1038/Ng1104-1133  0.622
2004 Clapcote SJ, Roder JC. Survey of embryonic stem cell line source strains in the water maze reveals superior reversal learning of 129S6/SvEvTac mice. Behavioural Brain Research. 152: 35-48. PMID 15135967 DOI: 10.1016/J.Bbr.2003.09.030  0.681
2003 Jamot L, Matthes HW, Simonin F, Kieffer BL, Roder JC. Differential involvement of the mu and kappa opioid receptors in spatial learning. Genes, Brain, and Behavior. 2: 80-92. PMID 12884965 DOI: 10.1034/J.1601-183X.2003.00013.X  0.34
2003 Metzler M, Li B, Gan L, Georgiou J, Gutekunst CA, Wang Y, Torre E, Devon RS, Oh R, Legendre-Guillemin V, Rich M, Alvarez C, Gertsenstein M, McPherson PS, Nagy A, ... ... Roder JC, et al. Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking. The Embo Journal. 22: 3254-66. PMID 12839988 DOI: 10.1093/Emboj/Cdg334  0.609
2003 Kotecha SA, Jackson MF, Al-Mahrouki A, Roder JC, Orser BA, MacDonald JF. Co-stimulation of mGluR5 and N-methyl-D-aspartate receptors is required for potentiation of excitatory synaptic transmission in hippocampal neurons. The Journal of Biological Chemistry. 278: 27742-9. PMID 12740378 DOI: 10.1074/Jbc.M301946200  0.318
2003 Yan J, Zhang Y, Roder J, McDonald RJ. Aging effects on spatial tuning of hippocampal place cells in mice. Experimental Brain Research. 150: 184-93. PMID 12677315 DOI: 10.1007/S00221-003-1396-6  0.357
2003 Georgiou J, Tropak MB, Roder JC. Myelin-Associated Glycoprotein Gene Myelin Biology and Disorders. 1: 421-467. DOI: 10.1016/B978-012439510-7/50070-X  0.47
2002 Bai D, Muller RU, Roder JC. Non-ionotropic cross-talk between AMPA and NMDA receptors in rodent hippocampal neurones. The Journal of Physiology. 543: 23-33. PMID 12181279 DOI: 10.1113/Jphysiol.2002.020321  0.561
2002 Wang S, Jia Z, Roder J, Murphy TH. AMPA receptor-mediated miniature synaptic calcium transients in GluR2 null mice. Journal of Neurophysiology. 88: 29-40. PMID 12091530 DOI: 10.1152/Jn.2002.88.1.29  0.321
2002 Koizumi S, Rosa P, Willars GB, Challiss RA, Taverna E, Francolini M, Bootman MD, Lipp P, Inoue K, Roder J, Jeromin A. Mechanisms underlying the neuronal calcium sensor-1-evoked enhancement of exocytosis in PC12 cells. The Journal of Biological Chemistry. 277: 30315-24. PMID 12034721 DOI: 10.1074/Jbc.M201132200  0.306
2002 Takeuchi J, Fulton J, Jia ZP, Abramov-Newerly W, Jamot L, Sud M, Coward D, Ralph M, Roder J, Yeomans J. Increased drinking in mutant mice with truncated M5 muscarinic receptor genes. Pharmacology, Biochemistry, and Behavior. 72: 117-23. PMID 11900778 DOI: 10.1016/S0091-3057(01)00725-0  0.34
2002 Yan J, Zhang Y, Jia Z, Taverna FA, McDonald RJ, Muller RU, Roder JC. Place-cell impairment in glutamate receptor 2 mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: RC204. PMID 11826150 DOI: 10.1523/Jneurosci.22-03-J0002.2002  0.62
2001 Henderson JT, Georgiou J, Jia Z, Robertson J, Elowe S, Roder JC, Pawson T. The receptor tyrosine kinase EphB2 regulates NMDA-dependent synaptic function. Neuron. 32: 1041-56. PMID 11754836 DOI: 10.1016/S0896-6273(01)00553-0  0.608
2001 Jia Z, Lu YM, Agopyan N, Roder J. Gene targeting reveals a role for the glutamate receptors mGluR5 and GluR2 in learning and memory. Physiology & Behavior. 73: 793-802. PMID 11566212 DOI: 10.1016/S0031-9384(01)00516-9  0.362
2001 Huber KM, Roder JC, Bear MF. Chemical induction of mGluR5- and protein synthesis--dependent long-term depression in hippocampal area CA1. Journal of Neurophysiology. 86: 321-5. PMID 11431513 DOI: 10.1152/Jn.2001.86.1.321  0.303
2001 Hu RQ, Cortez MA, Man HY, Roder J, Jia Z, Wang YT, Snead OC. Gamma-hydroxybutyric acid-induced absence seizures in GluR2 null mutant mice. Brain Research. 897: 27-35. PMID 11282355 DOI: 10.1016/S0006-8993(01)02076-5  0.336
2001 Iihara K, Joo DT, Henderson J, Sattler R, Taverna FA, Lourensen S, Orser BA, Roder JC, Tymianski M. The influence of glutamate receptor 2 expression on excitotoxicity in Glur2 null mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 2224-39. PMID 11264298 DOI: 10.1523/Jneurosci.21-07-02224.2001  0.361
2001 Huang Y, Lu W, Ali DW, Pelkey KA, Pitcher GM, Lu YM, Aoto H, Roder JC, Sasaki T, Salter MW, MacDonald JF. CAKbeta/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampus. Neuron. 29: 485-96. PMID 11239437 DOI: 10.1016/S0896-6273(01)00220-3  0.319
2000 Oliveira-Dos-Santos AJ, Matsumoto G, Snow BE, Bai D, Houston FP, Whishaw IQ, Mariathasan S, Sasaki T, Wakeham A, Ohashi PS, Roder JC, Barnes CA, Siderovski DP, Penninger JM. Regulation of T cell activation, anxiety, and male aggression by RGS2. Proceedings of the National Academy of Sciences of the United States of America. 97: 12272-7. PMID 11027316 DOI: 10.1073/Pnas.220414397  0.366
2000 Janus C, D'Amelio S, Amitay O, Chishti MA, Strome R, Fraser P, Carlson GA, Roder JC, St George-Hyslop P, Westaway D. Spatial learning in transgenic mice expressing human presenilin 1 (PS1) transgenes. Neurobiology of Aging. 21: 541-9. PMID 10924767 DOI: 10.1016/S0197-4580(00)00107-X  0.39
2000 Xiong Z, O'Hanlon D, Becker LE, Roder J, MacDonald JF, Marks A. Enhanced calcium transients in glial cells in neonatal cerebellar cultures derived from S100B null mice. Experimental Cell Research. 257: 281-9. PMID 10837142 DOI: 10.1006/Excr.2000.4902  0.368
2000 Lei S, Jackson MF, Jia Z, Roder J, Bai D, Orser BA, MacDonald JF. Cyclic GMP-dependent feedback inhibition of AMPA receptors is independent of PKG. Nature Neuroscience. 3: 559-65. PMID 10816311 DOI: 10.1038/75729  0.321
2000 Lu YM, Mansuy IM, Kandel ER, Roder J. Calcineurin-mediated LTD of GABAergic inhibition underlies the increased excitability of CA1 neurons associated with LTP. Neuron. 26: 197-205. PMID 10798404 DOI: 10.1016/S0896-6273(00)81150-2  0.31
2000 Taverna F, Xiong ZG, Brandes L, Roder JC, Salter MW, MacDonald JF. The Lurcher mutation of an alpha-amino-3-hydroxy-5-methyl- 4-isoxazolepropionic acid receptor subunit enhances potency of glutamate and converts an antagonist to an agonist. The Journal of Biological Chemistry. 275: 8475-9. PMID 10722683 DOI: 10.1074/Jbc.275.12.8475  0.3
1999 Joo DT, Xiong Z, MacDonald JF, Jia Z, Roder J, Sonner J, Orser BA. Blockade of glutamate receptors and barbiturate anesthesia: increased sensitivity to pentobarbital-induced anesthesia despite reduced inhibition of AMPA receptors in GluR2 null mutant mice. Anesthesiology. 91: 1329-41. PMID 10551584 DOI: 10.1097/00000542-199911000-00025  0.368
1999 Xiong ZG, Pelkey KA, Lu WY, Lu YM, Roder JC, MacDonald JF, Salter MW. Src potentiation of NMDA receptors in hippocampal and spinal neurons is not mediated by reducing zinc inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: RC37. PMID 10531471 DOI: 10.1523/Jneurosci.19-21-J0003.1999  0.309
1999 Hodgson JG, Agopyan N, Gutekunst CA, Leavitt BR, LePiane F, Singaraja R, Smith DJ, Bissada N, McCutcheon K, Nasir J, Jamot L, Li XJ, Stevens ME, Rosemond E, Roder JC, et al. A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration. Neuron. 23: 181-92. PMID 10402204 DOI: 10.1016/S0896-6273(00)80764-3  0.375
1998 Mainen ZF, Jia Z, Roder J, Malinow R. Use-dependent AMPA receptor block in mice lacking GluR2 suggests postsynaptic site for LTP expression. Nature Neuroscience. 1: 579-86. PMID 10196565 DOI: 10.1038/2812  0.324
1998 Gerlai R, Henderson JT, Roder JC, Jia Z. Multiple behavioral anomalies in GluR2 mutant mice exhibiting enhanced LTP. Behavioural Brain Research. 95: 37-45. PMID 9754875 DOI: 10.1016/S0166-4328(98)00002-3  0.622
1998 Ramer MS, Kawaja MD, Henderson JT, Roder JC, Bisby MA. Glial overexpression of NGF enhances neuropathic pain and adrenergic sprouting into DRG following chronic sciatic constriction in mice. Neuroscience Letters. 251: 53-6. PMID 9714463 DOI: 10.1016/S0304-3940(98)00493-5  0.318
1998 Gerlai R, Roder JC, Hampson DR. Altered spatial learning and memory in mice lacking the mGluR4 subtype of metabotropic glutamate receptor. Behavioral Neuroscience. 112: 525-32. PMID 9676970 DOI: 10.1037//0735-7044.112.3.525  0.581
1998 Lu YM, Roder JC, Davidow J, Salter MW. Src activation in the induction of long-term potentiation in CA1 hippocampal neurons. Science (New York, N.Y.). 279: 1363-7. PMID 9478899 DOI: 10.1126/Science.279.5355.1363  0.328
1997 Whitaker-Azmitia PM, Wingate M, Borella A, Gerlai R, Roder J, Azmitia EC. Transgenic mice overexpressing the neurotrophic factor S-100 beta show neuronal cytoskeletal and behavioral signs of altered aging processes: implications for Alzheimer's disease and Down's syndrome. Brain Research. 776: 51-60. PMID 9439795 DOI: 10.1016/S0006-8993(97)01002-0  0.548
1997 Vabnick I, Messing A, Chiu SY, Levinson SR, Schachner M, Roder J, Li C, Novakovic S, Shrager P. Sodium channel distribution in axons of hypomyelinated and MAG null mutant mice. Journal of Neuroscience Research. 50: 321-36. PMID 9373041 DOI: 10.1002/(Sici)1097-4547(19971015)50:2<321::Aid-Jnr20>3.0.Co;2-9  0.311
1997 Silva AJ, Simpson EM, Takahashi JS, Lipp HP, Nakanishi S, Wehner JM, Giese KP, Tully T, Abel T, Chapman PF, Fox K, Grant S, Itohara S, Lathe R, Mayford M, ... ... Roder J, et al. Mutant mice and neuroscience: Recommendations concerning genetic background Neuron. 19: 755-759. PMID 9354323 DOI: 10.1016/S0896-6273(00)80958-7  0.345
1997 Lu YM, Jia Z, Janus C, Henderson JT, Gerlai R, Wojtowicz JM, Roder JC. Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5196-205. PMID 9185557 DOI: 10.1523/Jneurosci.17-13-05196.1997  0.58
1996 Li M, Shibata A, Li C, Braun PE, McKerracher L, Roder J, Kater SB, David S. Myelin-associated glycoprotein inhibits neurite/axon growth and causes growth cone collapse. Journal of Neuroscience Research. 46: 404-14. PMID 8950700 DOI: 10.1002/(Sici)1097-4547(19961115)46:4<404::Aid-Jnr2>3.0.Co;2-K  0.322
1996 Gerlai R, Roder J. Spatial and nonspatial learning in mice: effects of S100 beta overexpression and age. Neurobiology of Learning and Memory. 66: 143-54. PMID 8946407 DOI: 10.1006/Nlme.1996.0055  0.576
1996 Jia Z, Agopyan N, Miu P, Xiong Z, Henderson J, Gerlai R, Taverna FA, Velumian A, MacDonald J, Carlen P, Abramow-Newerly W, Roder J. Enhanced LTP in mice deficient in the AMPA receptor GluR2. Neuron. 17: 945-56. PMID 8938126 DOI: 10.1016/S0896-6273(00)80225-1  0.59
1996 Roder JK, Roder JC, Gerlai R. Memory and the effect of cold shock in the water maze in S100 beta transgenic mice. Physiology & Behavior. 60: 611-5. PMID 8840925 DOI: 10.1016/S0031-9384(96)80038-2  0.581
1996 Pekhletski R, Gerlai R, Overstreet LS, Huang XP, Agopyan N, Slater NT, Abramow-Newerly W, Roder JC, Hampson DR. Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 6364-73. PMID 8815915 DOI: 10.1523/Jneurosci.16-20-06364.1996  0.587
1996 Roder JK, Roder JC, Gerlai R. Conspecific exploration in the T-maze: abnormalities in S100 beta transgenic mice. Physiology & Behavior. 60: 31-6. PMID 8804639 DOI: 10.1016/0031-9384(95)02247-3  0.599
1996 Ng WP, Cartel N, Li C, Roder J, Lozano A. Myelin from MAG-deficient mice is a strong inhibitor of neurite outgrowth. Neuroreport. 7: 861-4. PMID 8724661 DOI: 10.1097/00001756-199603220-00005  0.319
1996 Poplonski L, Vukusic B, Pawling J, Clapoff S, Roder J, Hozumi N, Wither J. Tolerance is overcome in beef insulin-transgenic mice by activation of low-affinity autoreactive T cells. European Journal of Immunology. 26: 601-9. PMID 8605927 DOI: 10.1002/Eji.1830260315  0.306
1996 Baskys A, Gerlai R, Pekhletski R, Roder J, Hampson D. Physiological and behavioral studies of mice Lacking type 4 mGluRS Neuropharmacology. 35: A2. DOI: 10.1016/0028-3908(96)84654-5  0.571
1994 Gerlai R, Marks A, Roder J. T-maze spontaneous alternation rate is decreased in S100 beta transgenic mice. Behavioral Neuroscience. 108: 100-6. PMID 8192834 DOI: 10.1037//0735-7044.108.1.100  0.554
1994 Shpitz B, Chambers CA, Singhal AB, Hozumi N, Fernandes BJ, Roifman CM, Weiner LM, Roder JC, Gallinger S. High level functional engraftment of severe combined immunodeficient mice with human peripheral blood lymphocytes following pretreatment with radiation and anti-asialo GM1. Journal of Immunological Methods. 169: 1-15. PMID 7907638 DOI: 10.1016/0022-1759(94)90119-8  0.321
1994 Li C, Tropak MB, Gerlai R, Clapoff S, Abramow-Newerly W, Trapp B, Peterson A, Roder J. Myelination in the absence of myelin-associated glycoprotein. Nature. 369: 747-50. PMID 7516497 DOI: 10.1038/369747A0  0.535
1993 Gerlai R, Roder J. Female specific hyperactivity in S100 beta transgenic mice does not habituate in open-field. Behavioural Brain Research. 59: 119-24. PMID 8155278 DOI: 10.1016/0166-4328(93)90157-L  0.56
1992 Friend W, Clapoff S, Landry C, Becker L, O'Hanlon D, Allore R, Brown I, Marks A, Roder J, Dunn R. Cell-specific expression of high levels of human S100 beta in transgenic mouse brain is dependent on gene dosage. The Journal of Neuroscience. 12: 4337-4346. DOI: 10.1523/Jneurosci.12-11-04337.1992  0.302
1987 Barton DE, Arquint M, Roder J, Dunn R, Francke U. The myelin-associated glycoprotein gene: mapping to human chromosome 19 and mouse chromosome 7 and expression in quivering mice. Genomics. 1: 107-112. PMID 2447011 DOI: 10.1016/0888-7543(87)90002-4  0.305
1986 Lauzon RJ, Siminovitch KA, Fulop GM, Phillips RA, Roder JC. An expanded population of natural killer cells in mice with severe combined immunodeficiency (SCID) lack rearrangement and expression of T cell receptor genes. The Journal of Experimental Medicine. 164: 1797-802. PMID 3772298 DOI: 10.1084/Jem.164.5.1797  0.309
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