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Aryn Gittis, Ph.D. - Publications

Affiliations: 
Carnegie Mellon University, Pittsburgh, PA 
Area:
basal ganglia, Parkinson's disease
Website:
https://www.bio.cmu.edu/labs/gittis/
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Aristieta A, Parker JE, Gao YE, Rubin JE, Gittis AH. Dopamine depletion weakens direct pathway modulation of SNr neurons. Neurobiology of Disease. 196: 106512. PMID 38670278 DOI: 10.1016/j.nbd.2024.106512  0.407
2023 Jeong M, Choi JH, Jang H, Sohn DH, Wang Q, Lee J, Yao L, Lee EJ, Fan J, Pratelli M, Wang EH, Snyder CN, Wang XY, Shin S, Gittis AH, et al. Viral vector-mediated transgene delivery with novel recombinase systems for targeting neuronal populations defined by multiple features. Neuron. PMID 37909037 DOI: 10.1016/j.neuron.2023.09.038  0.757
2023 Whalen TC, Parker JE, Gittis AH, Rubin JE. Transmission of delta band (0.5-4 Hz) oscillations from the globus pallidus to the substantia nigra pars reticulata in dopamine depletion. Journal of Computational Neuroscience. PMID 37266768 DOI: 10.1007/s10827-023-00853-z  0.316
2023 Isett BR, Nguyen KP, Schwenk JC, Yurek JR, Snyder CN, Vounatsos MV, Adegbesan KA, Ziausyte U, Gittis AH. The indirect pathway of the basal ganglia promotes transient punishment but not motor suppression. Neuron. PMID 37207651 DOI: 10.1016/j.neuron.2023.04.017  0.771
2021 Spix TA, Nanivadekar S, Toong N, Kaplow IM, Isett BR, Goksen Y, Pfenning AR, Gittis AH. Population-specific neuromodulation prolongs therapeutic benefits of deep brain stimulation. Science (New York, N.Y.). 374: 201-206. PMID 34618556 DOI: 10.1126/science.abi7852  0.725
2020 Lawler AJ, Brown AR, Bouchard RS, Toong N, Kim Y, Velraj N, Fox G, Kleyman M, Kang B, Gittis AH, Pfenning AR. Cell type-specific oxidative stress genomic signatures in the globus pallidus of dopamine depleted mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33188066 DOI: 10.1523/JNEUROSCI.1634-20.2020  0.414
2020 Spix T, Gittis A. Debunking an old theory. Elife. 9. PMID 33064076 DOI: 10.7554/eLife.62694  0.757
2020 Phillips RS, Rosner I, Gittis AH, Rubin JE. The effects of chloride dynamics on substantia nigra pars reticulata responses to pallidal and striatal inputs. Elife. 9. PMID 32894224 DOI: 10.7554/Elife.55592  0.338
2020 Whalen TC, Willard AM, Rubin JE, Gittis AH. Delta Oscillations Are a Robust Biomarker of Dopamine Depletion Severity and Motor Dysfunction in Awake Mice. Journal of Neurophysiology. PMID 32579421 DOI: 10.1152/Jn.00158.2020  0.809
2019 Kodama T, Gittis A, Shin M, Kelleher K, Kolkman K, McElvain L, Lam M, du Lac S. Graded co-expression of ion channel, neurofilament, and synaptic genes in fast-spiking vestibular nucleus neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31719168 DOI: 10.1523/Jneurosci.1500-19.2019  0.761
2019 Corbit VL, Gittis AH, Ahmari SE. A Model of Restraint: Nucleus Accumbens Fast-Spiking Interneurons Inhibit Unwanted Actions. Biological Psychiatry. 86: 804-806. PMID 31668219 DOI: 10.1016/J.Biopsych.2019.09.014  0.772
2019 Ramirez-Zamora A, Giordano J, Boyden ES, Gradinaru V, Gunduz A, Starr PA, Sheth SA, McIntyre CC, Fox MD, Vitek J, Vedam-Mai V, Akbar U, Almeida L, Bronte-Stewart HM, Mayberg HS, ... ... Gittis AH, et al. Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics. Frontiers in Neuroscience. 13: 936. PMID 31572109 DOI: 10.3389/Fnins.2019.00936  0.303
2019 Willard AM, Isett BR, Whalen TC, Mastro KJ, Ki CS, Mao X, Gittis AH. State transitions in the substantia nigra reticulata predict the onset of motor deficits in models of progressive dopamine depletion in mice. Elife. 8. PMID 30839276 DOI: 10.7554/Elife.42746  0.753
2019 Corbit VL, Manning EE, Gittis AH, Ahmari SE. Strengthened inputs from secondary motor cortex to striatum in a mouse model of compulsive behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30737313 DOI: 10.1523/Jneurosci.1728-18.2018  0.791
2019 Eisinger RS, Cernera S, Gittis A, Gunduz A, Okun MS. A review of basal ganglia circuits and physiology: Application to deep brain stimulation. Parkinsonism & Related Disorders. PMID 30658883 DOI: 10.1016/J.Parkreldis.2019.01.009  0.334
2017 Corbit VL, Ahmari SE, Gittis AH. A Corticostriatal Balancing Act Supports Skill Learning. Neuron. 96: 253-255. PMID 29024650 DOI: 10.1016/J.Neuron.2017.09.046  0.756
2017 Mastro KJ, Zitelli KT, Willard AM, Leblanc KH, Kravitz AV, Gittis AH. Cell-specific pallidal intervention induces long-lasting motor recovery in dopamine-depleted mice. Nature Neuroscience. PMID 28481350 DOI: 10.1038/Nn.4559  0.772
2016 Xiao Chuan Ong, Willard A, Forssell M, Gittis A, Fedder GK. A silicon neural probe fabricated using DRIE on bonded thin silicon. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2016: 4885-4888. PMID 28269365 DOI: 10.1109/EMBC.2016.7591822  0.754
2016 Ong XC, Willard A, Forssell M, Gittis A, Fedder GK, Xiao Chuan Ong, Willard A, Forssell M, Gittis A, Fedder GK, Forssell M, Gittis A, Fedder GK, Willard A, Ong XC. A silicon neural probe fabricated using DRIE on bonded thin silicon. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2016: 4885-4888. PMID 28227607 DOI: 10.1109/EMBC.2016.7591822  0.754
2016 Corbit VL, Whalen TC, Zitelli KT, Crilly SY, Rubin JE, Gittis AH. Pallidostriatal Projections Promote β Oscillations in a Dopamine-Depleted Biophysical Network Model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 5556-71. PMID 27194335 DOI: 10.1523/Jneurosci.0339-16.2016  0.784
2015 Willard AM, Gittis AH. Mapping neural circuits with CLARITY. Elife. 4. PMID 26452201 DOI: 10.7554/Elife.11409  0.766
2015 Willard AM, Bouchard RS, Gittis AH. Differential degradation of motor deficits during gradual dopamine depletion with 6-hydroxydopamine in mice. Neuroscience. 301: 254-67. PMID 26067595 DOI: 10.1016/J.Neuroscience.2015.05.068  0.805
2015 Mastro KJ, Gittis AH. Striking the right balance: cortical modulation of the subthalamic nucleus-globus pallidus circuit. Neuron. 85: 233-5. PMID 25611504 DOI: 10.1016/J.Neuron.2014.12.062  0.802
2015 Willard AM, Bouchard RS, Gittis AH. Differential degradation of motor deficits during gradual dopamine depletion with 6-hydroxydopamine in mice Neuroscience. 301: 254-267. DOI: 10.1016/j.neuroscience.2015.05.068  0.796
2014 Mastro KJ, Bouchard RS, Holt HA, Gittis AH. Transgenic mouse lines subdivide external segment of the globus pallidus (GPe) neurons and reveal distinct GPe output pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2087-99. PMID 24501350 DOI: 10.1523/Jneurosci.4646-13.2014  0.808
2012 Gittis AH, Kreitzer AC. Striatal microcircuitry and movement disorders. Trends in Neurosciences. 35: 557-64. PMID 22858522 DOI: 10.1016/j.tins.2012.06.008  0.661
2011 Gittis AH, Leventhal DK, Fensterheim BA, Pettibone JR, Berke JD, Kreitzer AC. Selective inhibition of striatal fast-spiking interneurons causes dyskinesias. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 15727-31. PMID 22049415 DOI: 10.1523/Jneurosci.3875-11.2011  0.704
2011 Gittis AH, Hang GB, LaDow ES, Shoenfeld LR, Atallah BV, Finkbeiner S, Kreitzer AC. Rapid target-specific remodeling of fast-spiking inhibitory circuits after loss of dopamine. Neuron. 71: 858-68. PMID 21903079 DOI: 10.1016/J.Neuron.2011.06.035  0.793
2011 Higley MJ, Gittis AH, Oldenburg IA, Balthasar N, Seal RP, Edwards RH, Lowell BB, Kreitzer AC, Sabatini BL. Cholinergic interneurons mediate fast VGluT3-dependent glutamatergic transmission in the striatum. Plos One. 6: e19155. PMID 21544206 DOI: 10.1371/journal.pone.0019155  0.735
2010 Gittis AH, Moghadam SH, du Lac S. Mechanisms of sustained high firing rates in two classes of vestibular nucleus neurons: differential contributions of resurgent Na, Kv3, and BK currents. Journal of Neurophysiology. 104: 1625-34. PMID 20592126 DOI: 10.1152/jn.00378.2010  0.676
2010 Gittis AH, Nelson AB, Thwin MT, Palop JJ, Kreitzer AC. Distinct roles of GABAergic interneurons in the regulation of striatal output pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2223-34. PMID 20147549 DOI: 10.1523/Jneurosci.4870-09.2010  0.771
2008 Gittis AH, du Lac S. Similar properties of transient, persistent, and resurgent Na currents in GABAergic and non-GABAergic vestibular nucleus neurons. Journal of Neurophysiology. 99: 2060-5. PMID 18287543 DOI: 10.1152/jn.01389.2007  0.672
2007 Gittis AH, du Lac S. Firing properties of GABAergic versus non-GABAergic vestibular nucleus neurons conferred by a differential balance of potassium currents. Journal of Neurophysiology. 97: 3986-96. PMID 17392422 DOI: 10.1152/jn.00141.2007  0.674
2006 Gittis AH, du Lac S. Intrinsic and synaptic plasticity in the vestibular system. Current Opinion in Neurobiology. 16: 385-90. PMID 16842990 DOI: 10.1016/j.conb.2006.06.012  0.684
2005 Nelson AB, Gittis AH, du Lac S. Decreases in CaMKII activity trigger persistent potentiation of intrinsic excitability in spontaneously firing vestibular nucleus neurons. Neuron. 46: 623-31. PMID 15944130 DOI: 10.1016/J.Neuron.2005.04.009  0.772
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