Eva Czirr, Dr rer Nat - Publications

Neurology Stanford University, Palo Alto, CA 
Neurodegeneration, Alzheimer's disease

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Czirr E, Castello NA, Mosher KI, Castellano JM, Hinkson IV, Lucin KM, Baeza-Raja B, Ryu JK, Li L, Farina SN, Belichenko NP, Longo FM, Akassoglou K, Britschgi M, Cirrito JR, et al. Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity. The Journal of Experimental Medicine. PMID 28298456 DOI: 10.1084/jem.20162011  1
2016 Middeldorp J, Lehallier B, Villeda SA, Miedema SS, Evans E, Czirr E, Zhang H, Luo J, Stan T, Mosher KI, Masliah E, Wyss-Coray T. Preclinical Assessment of Young Blood Plasma for Alzheimer Disease. Jama Neurology. PMID 27598869 DOI: 10.1001/jamaneurol.2016.3185  1
2014 Li WW, Guo TZ, Shi X, Czirr E, Stan T, Sahbaie P, Wyss-Coray T, Kingery WS, Clark JD. Autoimmunity contributes to nociceptive sensitization in a mouse model of complex regional pain syndrome. Pain. 155: 2377-89. PMID 25218828 DOI: 10.1016/j.pain.2014.09.007  1
2014 Kleinberger G, Yamanishi Y, Suárez-Calvet M, Czirr E, Lohmann E, Cuyvers E, Struyfs H, Pettkus N, Wenninger-Weinzierl A, Mazaheri F, Tahirovic S, Lleó A, Alcolea D, Fortea J, Willem M, et al. TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis. Science Translational Medicine. 6: 243ra86. PMID 24990881 DOI: 10.1126/scitranslmed.3009093  1
2013 Lucin KM, O'Brien CE, Bieri G, Czirr E, Mosher KI, Abbey RJ, Mastroeni DF, Rogers J, Spencer B, Masliah E, Wyss-Coray T. Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease. Neuron. 79: 873-86. PMID 24012002 DOI: 10.1016/j.neuron.2013.06.046  1
2012 Czirr E, Wyss-Coray T. The immunology of neurodegeneration. The Journal of Clinical Investigation. 122: 1156-63. PMID 22466657 DOI: 10.1172/JCI58656  1
2011 Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, Lucin KM, Czirr E, Park JS, Couillard-Després S, Aigner L, et al. The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature. 477: 90-4. PMID 21886162 DOI: 10.1038/nature10357  1
2011 Hahn S, Brüning T, Ness J, Czirr E, Baches S, Gijsen H, Korth C, Pietrzik CU, Bulic B, Weggen S. Presenilin-1 but not amyloid precursor protein mutations present in mouse models of Alzheimer's disease attenuate the response of cultured cells to γ-secretase modulators regardless of their potency and structure. Journal of Neurochemistry. 116: 385-95. PMID 21091478 DOI: 10.1111/j.1471-4159.2010.07118.x  1
2009 Jäger S, Leuchtenberger S, Martin A, Czirr E, Wesselowski J, Dieckmann M, Waldron E, Korth C, Koo EH, Heneka M, Weggen S, Pietrzik CU. alpha-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Abeta generation. Journal of Neurochemistry. 111: 1369-82. PMID 19804379 DOI: 10.1111/j.1471-4159.2009.06420.x  1
2009 Leuchtenberger S, Maler J, Czirr E, Ness J, Lichtenthaler SF, Esselmann H, Pietrzik CU, Wiltfang J, Weggen S. Nonsteroidal anti-inflammatory drugs and ectodomain shedding of the amyloid precursor protein. Neuro-Degenerative Diseases. 6: 1-8. PMID 18349521 DOI: 10.1159/000121391  1
2008 Czirr E, Cottrell BA, Leuchtenberger S, Kukar T, Ladd TB, Esselmann H, Paul S, Schubenel R, Torpey JW, Pietrzik CU, Golde TE, Wiltfang J, Baumann K, Koo EH, Weggen S. Independent generation of Abeta42 and Abeta38 peptide species by gamma-secretase. The Journal of Biological Chemistry. 283: 17049-54. PMID 18426795 DOI: 10.1074/jbc.M802912200  1
2007 Czirr E, Leuchtenberger S, Dorner-Ciossek C, Schneider A, Jucker M, Koo EH, Pietrzik CU, Baumann K, Weggen S. Insensitivity to Abeta42-lowering nonsteroidal anti-inflammatory drugs and gamma-secretase inhibitors is common among aggressive presenilin-1 mutations. The Journal of Biological Chemistry. 282: 24504-13. PMID 17573346 DOI: 10.1074/jbc.M700618200  1
2007 Weggen S, Czirr E, Leuchtenberger S, Eriksen J. Nonsteroidal anti-inflammatory drugs (NSAIDs) and derived Aβ42-lowering molecules for treatment and prevention of Alzheimer's disease (AD) Pharmacological Mechanisms in Alzheimer's Therapeutics. 167-193. DOI: 10.1007/978-0-387-71522-3_11  1
2006 Czirr E, Weggen S. Gamma-secretase modulation with Abeta42-lowering nonsteroidal anti-inflammatory drugs and derived compounds. Neuro-Degenerative Diseases. 3: 298-304. PMID 17047371 DOI: 10.1159/000095270  1
2006 Leuchtenberger S, Kummer MP, Kukar T, Czirr E, Teusch N, Sagi SA, Berdeaux R, Pietrzik CU, Ladd TB, Golde TE, Koo EH, Weggen S. Inhibitors of Rho-kinase modulate amyloid-beta (Abeta) secretion but lack selectivity for Abeta42. Journal of Neurochemistry. 96: 355-65. PMID 16300630 DOI: 10.1111/j.1471-4159.2005.03553.x  1
2004 Donkor FF, Mönnich M, Czirr E, Hollemann T, Hoyer-Fender S. Outer dense fibre protein 2 (ODF2) is a self-interacting centrosomal protein with affinity for microtubules. Journal of Cell Science. 117: 4643-51. PMID 15340007 DOI: 10.1242/jcs.01303  1
2004 Gao S, Czirr E, Chung YG, Han Z, Latham KE. Genetic variation in oocyte phenotype revealed through parthenogenesis and cloning: correlation with differences in pronuclear epigenetic modification. Biology of Reproduction. 70: 1162-70. PMID 14681201 DOI: 10.1095/biolreprod.103.024216  1
2004 Hoyer-Fender S, Czirr E, Radde R, Turner JM, Mahadevaiah SK, Pehrson JR, Burgoyne PS. Localisation of histone macroH2A1.2 to the XY-body is not a response to the presence of asynapsed chromosome axes. Journal of Cell Science. 117: 189-98. PMID 14676273 DOI: 10.1242/jcs.00851  1
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