| Year |
Citation |
Score |
| 2024 |
Iamshanova O, Hämmerli AF, Ramaye E, Seljmani A, Ross-Kaschitza D, Schärz N, Essers M, Guichard S, Rougier JS, Abriel H. The dispensability of 14-3-3 proteins for the regulation of human cardiac sodium channel Nav1.5. Plos One. 19: e0298820. PMID 38452156 DOI: 10.1371/journal.pone.0298820 |
0.762 |
|
| 2023 |
Arullampalam P, Essers MC, Boukenna M, Guichard S, Rougier JS, Abriel H. Knockdown of the TRPM4 channel alters cardiac electrophysiology and hemodynamics in a sex- and age-dependent manner in mice. Physiological Reports. 11: e15783. PMID 37604672 DOI: 10.14814/phy2.15783 |
0.714 |
|
| 2023 |
Selimi Z, Rougier JS, Abriel H, Kucera JP. A detailed analysis of single-channel Na 1.5 recordings does not reveal any cooperative gating. The Journal of Physiology. 601: 3847-3868. PMID 37470338 DOI: 10.1113/JP284861 |
0.765 |
|
| 2023 |
Boukenna M, Rougier JS, Aghagolzadeh P, Pradervand S, Guichard S, Hämmerli AF, Pedrazzini T, Abriel H. Multiomics uncover the proinflammatory role of deletion after myocardial infarction in mice. American Journal of Physiology. Heart and Circulatory Physiology. 324: H504-H518. PMID 36800508 DOI: 10.1152/ajpheart.00671.2022 |
0.675 |
|
| 2022 |
Preti B, Rougier JS, Papapostolou I, Bochen F, Gerber CE, Abriel H, Lochner M, Peinelt C. Targeting Ion Channel TRPM4. Chimia. 76: 1039-1044. PMID 38069800 DOI: 10.2533/chimia.2022.1039 |
0.727 |
|
| 2022 |
Dokshokova L, Franzoso M, Di Bona A, Moro N, Sanchez Alonso JL, Prando V, Sandre M, Basso C, Faggian G, Abriel H, Marin O, Gorelik J, Zaglia T, Mongillo M. Nerve growth factor transfer from cardiomyocytes to innervating sympathetic neurons activates TrkA receptors at the neuro-cardiac junction. The Journal of Physiology. PMID 35413134 DOI: 10.1113/JP282828 |
0.346 |
|
| 2021 |
Arullampalam P, Preti B, Ross-Kaschitza D, Lochner M, Rougier JS, Abriel H. Species-Specific Effects of Cation Channel TRPM4 Small-Molecule Inhibitors. Frontiers in Pharmacology. 12: 712354. PMID 34335274 DOI: 10.3389/fphar.2021.712354 |
0.752 |
|
| 2021 |
Ozhathil LC, Rougier JS, Arullampalam P, Essers MC, Ross-Kaschitza D, Abriel H. Deletion of Alters the Function of the Na1.5 Channel in Murine Cardiac Myocytes. International Journal of Molecular Sciences. 22. PMID 33810249 DOI: 10.3390/ijms22073401 |
0.791 |
|
| 2021 |
Hu Y, Kaschitza DR, Essers M, Arullampalam P, Fujita T, Abriel H, Inoue R. Pathological activation of CaMKII induces arrhythmogenicity through TRPM4 overactivation. Pflugers Archiv : European Journal of Physiology. PMID 33392831 DOI: 10.1007/s00424-020-02507-w |
0.509 |
|
| 2020 |
Wang Z, Vermij SH, Sottas V, Shestak A, Ross-Kaschitza D, Zaklyazminskaya EV, Hudmon A, Pitt GS, Rougier JS, Abriel H. Calmodulin binds to the N-terminal domain of the cardiac sodium channel Na1.5. Channels (Austin, Tex.). 14: 268-286. PMID 32815768 DOI: 10.1080/19336950.2020.1805999 |
0.846 |
|
| 2020 |
Vermij SH, Rougier JS, Agulló-Pascual E, Rothenberg E, Delmar M, Abriel H. Single-molecule Localization of Na1.5 Reveals Different Modes of Reorganization at Cardiomyocyte Membrane Domains. Circulation. Arrhythmia and Electrophysiology. PMID 32536203 DOI: 10.1161/Circep.119.008241 |
0.826 |
|
| 2020 |
Amarouch MY, Kurt H, Delemotte L, Abriel H. Biophysical Characterization of Epigallocatechin-3-Gallate Effect on the Cardiac Sodium Channel Na1.5. Molecules (Basel, Switzerland). 25. PMID 32085432 DOI: 10.3390/Molecules25040902 |
0.803 |
|
| 2019 |
Vermij SH, Abriel H, Kucera JP. Modeling Depolarization Delay, Sodium Currents, and Electrical Potentials in Cardiac Transverse Tubules. Frontiers in Physiology. 10: 1487. PMID 31920695 DOI: 10.3389/Fphys.2019.01487 |
0.809 |
|
| 2019 |
Gillet L, Guichard S, Essers MC, Rougier JS, Abriel H. Dystrophin and calcium current are decreased in cardiomyocytes expressing Cre enzyme driven by αMHC but not TNT promoter. Scientific Reports. 9: 19422. PMID 31857666 DOI: 10.1038/S41598-019-55950-W |
0.823 |
|
| 2019 |
Casini S, Albesa M, Wang Z, Portero V, Ross-Kaschitza D, Rougier JS, Marchal GA, Chung WK, Bezzina CR, Abriel H, Remme CA. Functional Consequences of the -p.Y1977N Mutation within the PY Ubiquitylation Motif: Discrepancy between HEK293 Cells and Transgenic Mice. International Journal of Molecular Sciences. 20. PMID 31614475 DOI: 10.3390/Ijms20205033 |
0.835 |
|
| 2019 |
Neubauer J, Wang Z, Rougier JS, Abriel H, Rieubland C, Bartholdi D, Haas C, Medeiros-Domingo A. Functional characterization of a novel SCN5A variant associated with long QT syndrome and sudden cardiac death. International Journal of Legal Medicine. PMID 31455979 DOI: 10.1007/S00414-019-02141-X |
0.845 |
|
| 2019 |
Rougier JS, Essers MC, Gillet L, Guichard S, Sonntag S, Shmerling D, Abriel H. A Distinct Pool of Na1.5 Channels at the Lateral Membrane of Murine Ventricular Cardiomyocytes. Frontiers in Physiology. 10: 834. PMID 31333492 DOI: 10.3389/Fphys.2019.00834 |
0.846 |
|
| 2019 |
Vermij SH, Abriel H, Kucera JP. A fundamental evaluation of the electrical properties and function of cardiac transverse tubules. Biochimica Et Biophysica Acta. Molecular Cell Research. PMID 31269418 DOI: 10.1016/J.Bbamcr.2019.06.016 |
0.801 |
|
| 2019 |
Marionneau C, Abriel H. Cardiac Sodium Current Under Sympathetic Control. Circulation Research. 124: 674-676. PMID 30817259 DOI: 10.1161/Circresaha.119.314680 |
0.488 |
|
| 2019 |
Delalande C, Awale M, Rubin M, Probst D, Ozhathil LC, Gertsch J, Abriel H, Reymond JL. Optimizing TRPM4 inhibitors in the MHFP6 chemical space. European Journal of Medicinal Chemistry. 166: 167-177. PMID 30708257 DOI: 10.1016/J.Ejmech.2019.01.048 |
0.394 |
|
| 2018 |
van der Heyden MAG, Delisle BP, Abriel H. Editorial: Ion Channel Trafficking and Cardiac Arrhythmias. Frontiers in Physiology. 9: 1254. PMID 30319434 DOI: 10.3389/Fphys.2018.01254 |
0.583 |
|
| 2018 |
Chevalier M, Vermij SH, Wyler K, Gillet L, Keller I, Abriel H. Corrigendum: Transcriptomic analyses of murine ventricular cardiomyocytes. Scientific Data. 5: 180216. PMID 30299437 DOI: 10.1038/Sdata.2018.216 |
0.773 |
|
| 2018 |
Tamo L, Hibaoui Y, Kallol S, Alves MP, Albrecht C, Hostettler KE, Feki A, Rougier JS, Abriel H, Knudsen L, Gazdhar A, Geiser T. Generation of an alveolar epithelial type II cell line from induced pluripotent stem cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 30211653 DOI: 10.1152/Ajplung.00357.2017 |
0.674 |
|
| 2018 |
Chevalier M, Vermij SH, Wyler K, Gillet L, Keller I, Abriel H. Transcriptomic analyses of murine ventricular cardiomyocytes. Scientific Data. 5: 180170. PMID 30129933 DOI: 10.1038/Sdata.2018.170 |
0.839 |
|
| 2018 |
Bianchi B, Smith PA, Abriel H. The ion channel TRPM4 in murine experimental autoimmune encephalomyelitis and in a model of glutamate-induced neuronal degeneration. Molecular Brain. 11: 41. PMID 29996905 DOI: 10.1186/S13041-018-0385-4 |
0.74 |
|
| 2018 |
Neubauer J, Rougier JS, Abriel H, Haas C. Functional implications of a rare variant in the sodium channel β1B subunit () in a 5-month-old male sudden infant death syndrome case. Heartrhythm Case Reports. 4: 187-190. PMID 29915715 DOI: 10.1016/J.Hrcr.2018.01.010 |
0.706 |
|
| 2018 |
Ozhathil LC, Delalande C, Bianchi B, Nemeth G, Kappel S, Thomet U, Ross-Kaschitza D, Simonin C, Rubin M, Gertsch J, Lochner M, Peinelt C, Reymond JL, Abriel H. Identification of potent and selective small molecule inhibitors of the cation channel TRPM4. British Journal of Pharmacology. PMID 29579323 DOI: 10.1111/Bph.14220 |
0.726 |
|
| 2018 |
Bianchi B, Ozhathil LC, Medeiros-Domingo A, Gollob MH, Abriel H. Four TRPM4 Cation Channel Mutations Found in Cardiac Conduction Diseases Lead to Altered Protein Stability. Frontiers in Physiology. 9: 177. PMID 29568272 DOI: 10.3389/Fphys.2018.00177 |
0.796 |
|
| 2018 |
Casini S, Portero V, Rougier JS, Albesa M, Marchal GA, Chung WK, Bezzina CR, Abriel H, Remme CA. P265Functional characterization of a LQT3 mutation located in the PY motif of the cardiac sodium channel associated with altered channel ubiquitylation Cardiovascular Research. 114: S68-S68. DOI: 10.1093/Cvr/Cvy060.185 |
0.86 |
|
| 2017 |
Hichri E, Abriel H, Kucera JP. Distribution of cardiac sodium channels in clusters potentiates ephaptic interactions in the intercalated disc. The Journal of Physiology. PMID 29210458 DOI: 10.1113/Jp275351 |
0.566 |
|
| 2017 |
Hinard V, Britan A, Schaeffer M, Zahn-Zabal M, Thomet U, Rougier JS, Bairoch A, Abriel H, Gaudet P. Annotation of functional impact of voltage-gated sodium channel mutations. Human Mutation. PMID 28168870 DOI: 10.1002/Humu.23191 |
0.798 |
|
| 2017 |
Vermij SH, Abriel H, van Veen TA. Refining the molecular organization of the cardiac intercalated disc. Cardiovascular Research. PMID 28069669 DOI: 10.1093/Cvr/Cvw259 |
0.834 |
|
| 2017 |
Hichri E, Abriel H, Kucera JP. Ephaptic Effects Potentiate the Threshold Behavior of the Cardiac Sodium Current in a High Resolution Mathematical Model of a Narrow Intercellular Cleft Biophysical Journal. 112: 241a-242a. DOI: 10.1016/J.Bpj.2016.11.1322 |
0.615 |
|
| 2016 |
Eichel CA, Beuriot A, Chevalier MY, Rougier JS, Louault F, Dilanian G, Amour J, Coulombe A, Abriel H, Hatem SN, Balse E. Lateral Membrane-Specific MAGUK CASK Down-Regulates NaV1.5 Channel in Cardiac Myocytes. Circulation Research. 119: 544-56. PMID 27364017 DOI: 10.1161/Circresaha.116.309254 |
0.848 |
|
| 2016 |
Syam N, Chatel S, Ozhathil LC, Sottas V, Rougier JS, Baruteau A, Baron E, Amarouch MY, Daumy X, Probst V, Schott JJ, Abriel H. Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block. Journal of the American Heart Association. 5. PMID 27207958 DOI: 10.1161/Jaha.114.001625 |
0.823 |
|
| 2016 |
Schaub MC, Abriel H. 8th Ascona International Workshop on Cardiomyocyte Biology, 3-7 May, 2015 Integration of Developmental and Environmental Cues in the Heart Congressi Stefano Franscini, Monte Verità, Ascona, Switzerland. Biochimica Et Biophysica Acta. 1863: 1691-5. PMID 27091768 DOI: 10.1016/J.Bbamcr.2016.04.008 |
0.387 |
|
| 2016 |
Hinard V, Britan A, Rougier JS, Bairoch A, Abriel H, Gaudet P. ICEPO: the ion channel electrophysiology ontology. Database : the Journal of Biological Databases and Curation. 2016. PMID 27055825 DOI: 10.1093/Database/Baw017 |
0.748 |
|
| 2016 |
Mohler PJ, Abriel H. Complexity of Cardiac Ion Channel Macromolecular Complexes. Cardiovascular Research. PMID 26984855 DOI: 10.1093/Cvr/Cvw055 |
0.627 |
|
| 2016 |
Amarouch MY, Swan H, Leinonen J, Marjamaa A, Lahtinen AM, Kontula K, Toivonen L, Widen E, Abriel H. Antiarrhythmic Action of Flecainide in Polymorphic Ventricular Arrhythmias Caused by a Gain-of-Function Mutation in the Nav 1.5 Sodium Channel. Annals of Noninvasive Electrocardiology : the Official Journal of the International Society For Holter and Noninvasive Electrocardiology, Inc. 21: 343-51. PMID 26965448 DOI: 10.1111/Anec.12312 |
0.818 |
|
| 2016 |
Sottas V, Abriel H. Negative-dominance phenomenon with genetic variants of the cardiac sodium channel Nav1.5. Biochimica Et Biophysica Acta. 1863: 1791-8. PMID 26907222 DOI: 10.1016/J.Bbamcr.2016.02.013 |
0.851 |
|
| 2016 |
Daumy X, Amarouch MY, Lindenbaum P, Bonnaud S, Charpentier E, Bianchi B, Nafzger S, Baron E, Fouchard S, Thollet A, Kyndt F, Barc J, Le Scouarnec S, Makita N, Le Marec H, ... ... Abriel H, et al. Targeted resequencing identifies TRPM4 as a major gene predisposing to progressive familial heart block type I. International Journal of Cardiology. 207: 349-58. PMID 26820365 DOI: 10.1016/J.Ijcard.2016.01.052 |
0.82 |
|
| 2016 |
Rougier JS, Abriel H. Cardiac voltage-gated calcium channel macromolecular complexes. Biochimica Et Biophysica Acta. 1863: 1806-12. PMID 26707467 DOI: 10.1016/J.Bbamcr.2015.12.014 |
0.803 |
|
| 2016 |
Daumy X, Amarouch MY, Lindenbaum P, Bonnaud S, Charpentier E, Bianchi B, Nafzger S, Baron E, Fouchard S, Thollet A, Kyndt F, Barc J, Le Scouarnec S, Makita N, Le Marec H, ... ... Abriel H, et al. Targeted resequencing identifies TRPM4 as a major gene predisposing to progressive familial heart block type i International Journal of Cardiology. 207: 349-358. DOI: 10.1016/j.ijcard.2016.01.052 |
0.788 |
|
| 2015 |
Laedermann CJ, Abriel H, Decosterd I. Post-translational modifications of voltage-gated sodium channels in chronic pain syndromes. Frontiers in Pharmacology. 6: 263. PMID 26594175 DOI: 10.3389/Fphar.2015.00263 |
0.806 |
|
| 2015 |
Abriel H, Rougier JS, Jalife J. Ion channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac death. Circulation Research. 116: 1971-88. PMID 26044251 DOI: 10.1161/Circresaha.116.305017 |
0.787 |
|
| 2015 |
Abriel H. Genetic background of Brugada syndrome is more complex than what we would like it to be! Cardiovascular Research. 106: 351-2. PMID 25926434 DOI: 10.1093/Cvr/Cvv135 |
0.441 |
|
| 2015 |
Chen-Izu Y, Shaw RM, Pitt GS, Yarov-Yarovoy V, Sack JT, Abriel H, Aldrich RW, Belardinelli L, Cannell MB, Catterall WA, Chazin WJ, Chiamvimonvat N, Deschenes I, Grandi E, Hund TJ, et al. Na+ channel function, regulation, structure, trafficking and sequestration. The Journal of Physiology. 593: 1347-60. PMID 25772290 DOI: 10.1113/Jphysiol.2014.281428 |
0.595 |
|
| 2015 |
Marionneau C, Abriel H. Regulation of the cardiac Na+ channel NaV1.5 by post-translational modifications. Journal of Molecular and Cellular Cardiology. 82: 36-47. PMID 25748040 DOI: 10.1016/J.Yjmcc.2015.02.013 |
0.595 |
|
| 2015 |
Amarouch MY, Abriel H. Cellular hyper-excitability caused by mutations that alter the activation process of voltage-gated sodium channels. Frontiers in Physiology. 6: 45. PMID 25741286 DOI: 10.3389/Fphys.2015.00045 |
0.821 |
|
| 2015 |
Ossola D, Amarouch MY, Behr P, Vörös J, Abriel H, Zambelli T. Force-controlled patch clamp of beating cardiac cells. Nano Letters. 15: 1743-50. PMID 25639960 DOI: 10.1021/Nl504438Z |
0.786 |
|
| 2015 |
Saber S, Amarouch MY, Fazelifar AF, Haghjoo M, Emkanjoo Z, Alizadeh A, Houshmand M, Gavrilenko AV, Abriel H, Zaklyazminskaya EV. Complex genetic background in a large family with Brugada syndrome. Physiological Reports. 3. PMID 25626866 DOI: 10.14814/Phy2.12256 |
0.789 |
|
| 2015 |
Gillet L, Rougier JS, Shy D, Sonntag S, Mougenot N, Essers M, Shmerling D, Balse E, Hatem SN, Abriel H. Cardiac-specific ablation of synapse-associated protein SAP97 in mice decreases potassium currents but not sodium current. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 12: 181-92. PMID 25447080 DOI: 10.1016/J.Hrthm.2014.09.057 |
0.842 |
|
| 2015 |
Baruteau AE, Probst V, Abriel H. Inherited progressive cardiac conduction disorders. Current Opinion in Cardiology. 30: 33-9. PMID 25426816 DOI: 10.1097/Hco.0000000000000134 |
0.459 |
|
| 2015 |
Rougier JS, Albesa M, Syam N, Halet G, Abriel H, Viard P. Ubiquitin-specific protease USP2-45 acts as a molecular switch to promote α2δ-1-induced downregulation of Cav1.2 channels. Pflugers Archiv : European Journal of Physiology. 467: 1919-29. PMID 25366495 DOI: 10.1007/S00424-014-1636-6 |
0.843 |
|
| 2015 |
Suter MR, Bhuiyan ZA, Laedermann CJ, Kuntzer T, Schaller M, Stauffacher MW, Roulet E, Abriel H, Decosterd I, Wider C. p.L1612P, a novel voltage-gated sodium channel Nav1.7 mutation inducing a cold sensitive paroxysmal extreme pain disorder. Anesthesiology. 122: 414-23. PMID 25285947 DOI: 10.1097/Aln.0000000000000476 |
0.801 |
|
| 2015 |
Amarouch MY, Swan H, Leinonen J, Marjamaa A, Lahtinen AM, Kontula K, Toivonen L, Widen E, Abriel H. Antiarrhythmic Action of Flecainide in Polymorphic Ventricular Arrhythmias Caused by a Gain-of-Function Mutation in the Nav1.5 Sodium Channel Annals of Noninvasive Electrocardiology. DOI: 10.1016/S1878-6480(16)30436-0 |
0.809 |
|
| 2015 |
Rougier J, Abriel H. 0151 : Role a calcium/calmodulin-dependent serine protein kinase on Cav1.2 channel regulation Archives of Cardiovascular Diseases Supplements. 7: 167-168. DOI: 10.1016/S1878-6480(15)30101-4 |
0.788 |
|
| 2014 |
Amarouch MY, Kasimova MA, Tarek M, Abriel H. Functional interaction between S1 and S4 segments in voltage-gated sodium channels revealed by human channelopathies. Channels (Austin, Tex.). 8: 414-20. PMID 25483584 DOI: 10.4161/19336950.2014.958922 |
0.784 |
|
| 2014 |
Chevalier M, Amuzescu B, Gawali V, Todt H, Knott T, Scheel O, Abriel H. Late cardiac sodium current can be assessed using automated patch-clamp. F1000research. 3: 245. PMID 25383189 DOI: 10.12688/F1000Research.5544.1 |
0.708 |
|
| 2014 |
Shy D, Gillet L, Abriel H. Targeting the sodium channel NaV1.5 to specific membrane compartments of cardiac cells: not a simple task! Circulation Research. 115: 901-3. PMID 25378529 DOI: 10.1161/Circresaha.114.305305 |
0.85 |
|
| 2014 |
Gillet L, Shy D, Abriel H. Elucidating sodium channel NaV1.5 clustering in cardiac myocytes using super-resolution techniques. Cardiovascular Research. 104: 231-3. PMID 25341893 DOI: 10.1093/Cvr/Cvu221 |
0.864 |
|
| 2014 |
Swan H, Amarouch MY, Leinonen J, Marjamaa A, Kucera JP, Laitinen-Forsblom PJ, Lahtinen AM, Palotie A, Kontula K, Toivonen L, Abriel H, Widen E. Gain-of-function mutation of the SCN5A gene causes exercise-induced polymorphic ventricular arrhythmias. Circulation. Cardiovascular Genetics. 7: 771-81. PMID 25210054 DOI: 10.1161/Circgenetics.114.000703 |
0.805 |
|
| 2014 |
Shy D, Gillet L, Ogrodnik J, Albesa M, Verkerk AO, Wolswinkel R, Rougier JS, Barc J, Essers MC, Syam N, Marsman RF, van Mil AM, Rotman S, Redon R, Bezzina CR, ... ... Abriel H, et al. PDZ domain-binding motif regulates cardiomyocyte compartment-specific NaV1.5 channel expression and function. Circulation. 130: 147-60. PMID 24895455 DOI: 10.1161/Circulationaha.113.007852 |
0.834 |
|
| 2014 |
Laedermann CJ, Decosterd I, Abriel H. Ubiquitylation of voltage-gated sodium channels. Handbook of Experimental Pharmacology. 221: 231-50. PMID 24737239 DOI: 10.1007/978-3-642-41588-3_11 |
0.855 |
|
| 2014 |
Abriel H, Sottas V. Unexpected α-α interactions with NaV1.5 genetic variants in Brugada syndrome. Circulation. Cardiovascular Genetics. 7: 97-9. PMID 24736849 DOI: 10.1161/Circgenetics.114.000590 |
0.845 |
|
| 2014 |
Syam N, Rougier JS, Abriel H. Glycosylation of TRPM4 and TRPM5 channels: molecular determinants and functional aspects. Frontiers in Cellular Neuroscience. 8: 52. PMID 24605085 DOI: 10.3389/Fncel.2014.00052 |
0.856 |
|
| 2014 |
Clémençon B, Fine M, Lüscher B, Baumann MU, Surbek DV, Abriel H, Hediger MA. Expression, purification, and projection structure by single particle electron microscopy of functional human TRPM4 heterologously expressed in Xenopus laevis oocytes. Protein Expression and Purification. 95: 169-76. PMID 24333049 DOI: 10.1016/J.Pep.2013.11.017 |
0.491 |
|
| 2014 |
Hersch M, Peter B, Kang HM, Schüpfer F, Abriel H, Pedrazzini T, Eskin E, Beckmann JS, Bergmann S, Maurer F. Correction: Mapping genetic variants associated with beta-adrenergic responses in inbred mice (PLoS ONE) Plos One. 9. DOI: 10.1371/Annotation/16D5801B-2701-4Ec9-9D8E-278791A8A26A |
0.332 |
|
| 2014 |
Amarouch MY, Leinonen J, Marjamaa A, Kucera JP, Laitinen-Forsblom PJ, Lahtinen AM, Palotie A, Kontula K, Toivonen L, Abriel H, Widen E, Swan H. 0265: A novel SCN5A mutation associated with exercise-induced polymorphic ventricular arrhythmias resembling CPVT Archives of Cardiovascular Diseases Supplements. 6: 41-42. DOI: 10.1016/S1878-6480(14)71376-X |
0.8 |
|
| 2014 |
Gillet L, Shy D, Sonntag S, Rougier J, Verkerk A, Essers M, Marsman R, Shmerling D, Bezzina C, Remme CA, Abriel H. 0150: PDZ domain proteins interacting with Nav1.5 differentially regulate Nav1.5 channel pools in mouse cardiomyocytes Archives of Cardiovascular Diseases Supplements. 6: 40-41. DOI: 10.1016/S1878-6480(14)71373-4 |
0.857 |
|
| 2014 |
Abriel H. Cardiac Sodium Channel Disorders: One Gene with Many Genetic Variants Leading to Many Cardiac Phenotypes Cardiac Electrophysiology Clinics. 6: xv-xvi. DOI: 10.1016/J.Ccep.2014.08.009 |
0.57 |
|
| 2014 |
Abriel H. Cardiac Sodium Channel Nav1.5 and Drug-Induced Long QT Syndrome Cardiac Electrophysiology Clinics. 6: 777-783. DOI: 10.1016/J.Ccep.2014.08.006 |
0.567 |
|
| 2014 |
Syam N, Chatel S, Rougier J, Sottas V, Baruteau A, Probst V, Schott J, Abriel H. TRPM4 Genetic Variants in Patients with Congenital Atrio-Ventricular Block Biophysical Journal. 106: 762a. DOI: 10.1016/J.Bpj.2013.11.4192 |
0.812 |
|
| 2013 |
Reinhard K, Rougier JS, Ogrodnik J, Abriel H. Electrophysiological properties of mouse and epitope-tagged human cardiac sodium channel Na v1.5 expressed in HEK293 cells. F1000research. 2: 48. PMID 24555036 DOI: 10.12688/F1000Research.2-48.V2 |
0.825 |
|
| 2013 |
Abriel H, de Lange E, Kucera JP, Loussouarn G, Tarek M. Computational tools to investigate genetic cardiac channelopathies. Frontiers in Physiology. 4: 390. PMID 24421770 DOI: 10.3389/Fphys.2013.00390 |
0.472 |
|
| 2013 |
Andersen MN, Krzystanek K, Petersen F, Bomholtz SH, Olesen SP, Abriel H, Jespersen T, Rasmussen HB. A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein. The Journal of Biological Chemistry. 288: 36841-54. PMID 24214981 DOI: 10.1074/Jbc.M113.525931 |
0.459 |
|
| 2013 |
Laedermann CJ, Syam N, Pertin M, Decosterd I, Abriel H. β1- and β3- voltage-gated sodium channel subunits modulate cell surface expression and glycosylation of Nav1.7 in HEK293 cells. Frontiers in Cellular Neuroscience. 7: 137. PMID 24009557 DOI: 10.3389/Fncel.2013.00137 |
0.791 |
|
| 2013 |
Abriel H, Rougier JS. β-blockers in congenital short-QT syndrome as ion channel blockers. Journal of Cardiovascular Electrophysiology. 24: 1172-4. PMID 23890274 DOI: 10.1111/Jce.12204 |
0.743 |
|
| 2013 |
Gillet L, Shy D, Abriel H. NaV1.5 and interacting proteins in human arrhythmogenic cardiomyopathy. Future Cardiology. 9: 467-70. PMID 23834686 DOI: 10.2217/Fca.13.38 |
0.848 |
|
| 2013 |
Laedermann CJ, Cachemaille M, Kirschmann G, Pertin M, Gosselin RD, Chang I, Albesa M, Towne C, Schneider BL, Kellenberger S, Abriel H, Decosterd I. Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain. The Journal of Clinical Investigation. 123: 3002-13. PMID 23778145 DOI: 10.1172/Jci68996 |
0.813 |
|
| 2013 |
Pérez López I, Cariolato L, Maric D, Gillet L, Abriel H, Diviani D. A-kinase anchoring protein Lbc coordinates a p38 activating signaling complex controlling compensatory cardiac hypertrophy. Molecular and Cellular Biology. 33: 2903-17. PMID 23716597 DOI: 10.1128/Mcb.00031-13 |
0.704 |
|
| 2013 |
Sottas V, Rougier JS, Jousset F, Kucera JP, Shestak A, Makarov LM, Zaklyazminskaya EV, Abriel H. Characterization of 2 genetic variants of Na(v) 1.5-arginine 689 found in patients with cardiac arrhythmias. Journal of Cardiovascular Electrophysiology. 24: 1037-46. PMID 23692053 DOI: 10.1111/Jce.12173 |
0.847 |
|
| 2013 |
Pouly D, Debonneville A, Ruffieux-Daidié D, Maillard M, Abriel H, Loffing J, Staub O. Mice carrying ubiquitin-specific protease 2 (Usp2) gene inactivation maintain normal sodium balance and blood pressure. American Journal of Physiology. Renal Physiology. 305: F21-30. PMID 23552861 DOI: 10.1152/Ajprenal.00012.2013 |
0.468 |
|
| 2013 |
Rougier JS, Gavillet B, Abriel H. Proteasome inhibitor (MG132) rescues Nav1.5 protein content and the cardiac sodium current in dystrophin-deficient mdx (5cv) mice. Frontiers in Physiology. 4: 51. PMID 23532763 DOI: 10.3389/Fphys.2013.00051 |
0.837 |
|
| 2013 |
Amarouch MY, Syam N, Abriel H. Biochemical, single-channel, whole-cell patch clamp, and pharmacological analyses of endogenous TRPM4 channels in HEK293 cells. Neuroscience Letters. 541: 105-10. PMID 23428507 DOI: 10.1016/J.Neulet.2013.02.011 |
0.835 |
|
| 2013 |
Liu H, Chatel S, Simard C, Syam N, Salle L, Probst V, Morel J, Millat G, Lopez M, Abriel H, Schott JJ, Guinamard R, Bouvagnet P. Molecular genetics and functional anomalies in a series of 248 Brugada cases with 11 mutations in the TRPM4 channel. Plos One. 8: e54131. PMID 23382873 DOI: 10.1371/Journal.Pone.0054131 |
0.843 |
|
| 2013 |
Abriel H, Zaklyazminskaya EV. Cardiac channelopathies: genetic and molecular mechanisms. Gene. 517: 1-11. PMID 23266818 DOI: 10.1016/J.Gene.2012.12.061 |
0.605 |
|
| 2013 |
Suter MR, Kirschmann G, Laedermann CJ, Abriel H, Decosterd I. Rufinamide attenuates mechanical allodynia in a model of neuropathic pain in the mouse and stabilizes voltage-gated sodium channel inactivated state. Anesthesiology. 118: 160-72. PMID 23221868 DOI: 10.1097/Aln.0B013E318278Cade |
0.825 |
|
| 2013 |
Shy D, Gillet L, Abriel H. Cardiac sodium channel NaV1.5 distribution in myocytes via interacting proteins: the multiple pool model. Biochimica Et Biophysica Acta. 1833: 886-94. PMID 23123192 DOI: 10.1016/J.Bbamcr.2012.10.026 |
0.866 |
|
| 2013 |
Ossola D, Behr P, Amarouch M, Abriel H, Vörös J, Zambelli T. Fluidfm for Force Controlled Electrophysiology Biophysical Journal. 104: 502a. DOI: 10.1016/J.Bpj.2012.11.2771 |
0.72 |
|
| 2012 |
Abriel H, Zaklyazminskaya EV. A modern approach to classify missense mutations in cardiac channelopathy genes. Circulation. Cardiovascular Genetics. 5: 487-9. PMID 23074335 DOI: 10.1161/Circgenetics.112.964809 |
0.634 |
|
| 2012 |
Cachemaille M, Laedermann CJ, Pertin M, Abriel H, Gosselin RD, Decosterd I. Neuronal expression of the ubiquitin ligase Nedd4-2 in rat dorsal root ganglia: modulation in the spared nerve injury model of neuropathic pain. Neuroscience. 227: 370-80. PMID 23022218 DOI: 10.1016/J.Neuroscience.2012.09.044 |
0.798 |
|
| 2012 |
Rougier JS, Abriel H. Role of "non-cardiac" voltage-gated sodium channels in cardiac cells. Journal of Molecular and Cellular Cardiology. 53: 589-90. PMID 22967322 DOI: 10.1016/J.Yjmcc.2012.08.011 |
0.796 |
|
| 2012 |
Rougier JS, Abriel H. Unexpected dominance: Brugada syndrome SCN5A variants exert negative dominance via α-subunit interaction. Cardiovascular Research. 96: 1-3. PMID 22871588 DOI: 10.1093/Cvr/Cvs264 |
0.779 |
|
| 2012 |
Hersch M, Peter B, Kang HM, Schüpfer F, Abriel H, Pedrazzini T, Eskin E, Beckmann JS, Bergmann S, Maurer F. Mapping genetic variants associated with beta-adrenergic responses in inbred mice. Plos One. 7: e41032. PMID 22859963 DOI: 10.1371/Journal.Pone.0041032 |
0.394 |
|
| 2012 |
Balse E, Steele DF, Abriel H, Coulombe A, Fedida D, Hatem SN. Dynamic of ion channel expression at the plasma membrane of cardiomyocytes. Physiological Reviews. 92: 1317-58. PMID 22811429 DOI: 10.1152/Physrev.00041.2011 |
0.613 |
|
| 2012 |
Abriel H, Syam N, Sottas V, Amarouch MY, Rougier JS. TRPM4 channels in the cardiovascular system: physiology, pathophysiology, and pharmacology. Biochemical Pharmacology. 84: 873-81. PMID 22750058 DOI: 10.1016/J.Bcp.2012.06.021 |
0.839 |
|
| 2012 |
Abriel H. Cardiac sodium channel Na(v)1.5 mechanosensitivity is inhibited by ranolazine. Circulation. 125: 2681-3. PMID 22565937 DOI: 10.1161/Circulationaha.112.110908 |
0.664 |
|
| 2012 |
Zaklyazminskaya EV, Abriel H. Prevalence of Significant Genetic Variants in Congenital Long QT Syndrome is Largely Underestimated. Frontiers in Pharmacology. 3: 72. PMID 22557970 DOI: 10.3389/Fphar.2012.00072 |
0.422 |
|
| 2012 |
Krzystanek K, Rasmussen HB, Grunnet M, Staub O, Olesen SP, Abriel H, Jespersen T. Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 440-8. PMID 22024150 DOI: 10.1016/J.Hrthm.2011.10.026 |
0.609 |
|
| 2011 |
Sintra Grilo L, Carrupt PA, Abriel H, Daina A. Block of the hERG channel by bupivacaine: Electrophysiological and modeling insights towards stereochemical optimization. European Journal of Medicinal Chemistry. 46: 3486-98. PMID 21624711 DOI: 10.1016/J.Ejmech.2011.05.015 |
0.596 |
|
| 2011 |
Grilo LS, Schläpfer J, Fellmann F, Abriel H. Patient with syncope and LQTS carrying a mutation in the PAS domain of the hERG1 channel. Annals of Noninvasive Electrocardiology : the Official Journal of the International Society For Holter and Noninvasive Electrocardiology, Inc. 16: 213-8. PMID 21496174 DOI: 10.1111/J.1542-474X.2011.00419.X |
0.824 |
|
| 2011 |
Albesa M, Grilo LS, Gavillet B, Abriel H. Nedd4-2-dependent ubiquitylation and regulation of the cardiac potassium channel hERG1. Journal of Molecular and Cellular Cardiology. 51: 90-8. PMID 21463633 DOI: 10.1016/J.Yjmcc.2011.03.015 |
0.859 |
|
| 2011 |
Templin C, Ghadri JR, Rougier JS, Baumer A, Kaplan V, Albesa M, Sticht H, Rauch A, Puleo C, Hu D, Barajas-Martinez H, Antzelevitch C, Lüscher TF, Abriel H, Duru F. Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6). European Heart Journal. 32: 1077-88. PMID 21383000 DOI: 10.1093/Eurheartj/Ehr076 |
0.843 |
|
| 2011 |
Rougier JS, Albesa M, Abriel H, Viard P. Neuronal precursor cell-expressed developmentally down-regulated 4-1 (NEDD4-1) controls the sorting of newly synthesized Ca(V)1.2 calcium channels. The Journal of Biological Chemistry. 286: 8829-38. PMID 21220429 DOI: 10.1074/Jbc.M110.166520 |
0.825 |
|
| 2011 |
Petitprez S, Zmoos AF, Ogrodnik J, Balse E, Raad N, El-Haou S, Albesa M, Bittihn P, Luther S, Lehnart SE, Hatem SN, Coulombe A, Abriel H. SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes. Circulation Research. 108: 294-304. PMID 21164104 DOI: 10.1161/Circresaha.110.228312 |
0.841 |
|
| 2011 |
Albesa M, Ogrodnik J, Rougier JS, Abriel H. Regulation of the cardiac sodium channel Nav1.5 by utrophin in dystrophin-deficient mice. Cardiovascular Research. 89: 320-8. PMID 20952415 DOI: 10.1016/J.Hrthm.2010.09.031 |
0.834 |
|
| 2011 |
Suter MR, Kirschmann G, Abriel H, Decosterd I. Rufinamide alleviates mechanical allodynia in a mouse neuropathic pain model European Journal of Anaesthesiology. 28: 193. DOI: 10.1097/00003643-201106001-00622 |
0.222 |
|
| 2011 |
Laedermann C, Cachemaille M, Abriel H, Decosterd I. The ubiquitin ligase Nedd4-2 is a potent regulator of the voltage-gated sodium channel Nav1.7 and is implicated in neuropathic pain European Journal of Anaesthesiology. 28: 2. DOI: 10.1097/00003643-201106001-00006 |
0.829 |
|
| 2010 |
Grilo LS, Carrupt PA, Abriel H. Stereoselective Inhibition of the hERG1 Potassium Channel. Frontiers in Pharmacology. 1: 137. PMID 21833176 DOI: 10.3389/Fphar.2010.00137 |
0.798 |
|
| 2010 |
Pignier C, Rougier JS, Vié B, Culié C, Verscheure Y, Vacher B, Abriel H, Le Grand B. Selective inhibition of persistent sodium current by F 15845 prevents ischaemia-induced arrhythmias. British Journal of Pharmacology. 161: 79-91. PMID 20718741 DOI: 10.1111/J.1476-5381.2010.00884.X |
0.732 |
|
| 2010 |
Rougier JS, Albesa M, Abriel H. Ubiquitylation and SUMOylation of cardiac ion channels. Journal of Cardiovascular Pharmacology. 56: 22-8. PMID 20224423 DOI: 10.1097/Fjc.0B013E3181Daaff9 |
0.845 |
|
| 2010 |
Leoni AL, Gavillet B, Rougier JS, Marionneau C, Probst V, Le Scouarnec S, Schott JJ, Demolombe S, Bruneval P, Huang CL, Colledge WH, Grace AA, Le Marec H, Wilde AA, Mohler PJ, ... ... Abriel H, et al. Variable Na(v)1.5 protein expression from the wild-type allele correlates with the penetrance of cardiac conduction disease in the Scn5a(+/-) mouse model. Plos One. 5: e9298. PMID 20174578 DOI: 10.1371/Journal.Pone.0009298 |
0.827 |
|
| 2010 |
Grilo LS, Pruvot E, Grobéty M, Castella V, Fellmann F, Abriel H. Takotsubo cardiomyopathy and congenital long QT syndrome in a patient with a novel duplication in the Per-Arnt-Sim (PAS) domain of hERG1. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 7: 260-5. PMID 20004623 DOI: 10.1016/J.Hrthm.2009.09.026 |
0.781 |
|
| 2010 |
Stirnimann G, Petitprez S, Abriel H, Schwick NG. Brugada syndrome ECG provoked by the selective serotonin reuptake inhibitor fluvoxamine. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 12: 282-3. PMID 19875396 DOI: 10.1093/Europace/Eup332 |
0.853 |
|
| 2010 |
Abriel H. Cardiac sodium channel Na(v)1.5 and interacting proteins: Physiology and pathophysiology. Journal of Molecular and Cellular Cardiology. 48: 2-11. PMID 19744495 DOI: 10.1016/J.Yjmcc.2009.08.025 |
0.629 |
|
| 2010 |
Krzystanek K, Grunnet M, Olesen SP, Abriel H, Jespersen T. Regulation of the Cardiac Iks Channel Complex by Ubiquitylation and De-Ubiquitylation Biophysical Journal. 98: 534a. DOI: 10.1016/J.Bpj.2009.12.2897 |
0.645 |
|
| 2009 |
Michaud K, Fellmann F, Abriel H, Beckmann JS, Mangin P, Elger BS. Molecular autopsy in sudden cardiac death and its implication for families: discussion of the practical, legal and ethical aspects of the multidisciplinary collaboration. Swiss Medical Weekly. 139: 712-8. PMID 20047134 DOI: 10.4414/Smw.2009.12837 |
0.415 |
|
| 2009 |
Berthonneche C, Peter B, Schüpfer F, Hayoz P, Kutalik Z, Abriel H, Pedrazzini T, Beckmann JS, Bergmann S, Maurer F. Cardiovascular response to beta-adrenergic blockade or activation in 23 inbred mouse strains. Plos One. 4: e6610. PMID 19672458 DOI: 10.1371/Journal.Pone.0006610 |
0.366 |
|
| 2009 |
Kurokawa J, Abriel H. Neurohormonal regulation of cardiac ion channels in chronic heart failure. Journal of Cardiovascular Pharmacology. 54: 98-105. PMID 19597366 DOI: 10.1097/Fjc.0B013E3181B2B6D4 |
0.736 |
|
| 2009 |
Tfelt-Hansen J, Jespersen T, Hofman-Bang J, Rasmussen HB, Cedergreen P, Skovby F, Abriel H, Svendsen JH, Olesen SP, Christiansen M, Haunso S. Ventricular tachycardia in a Brugada syndrome patient caused by a novel deletion in SCN5A. The Canadian Journal of Cardiology. 25: 156-60. PMID 19279983 DOI: 10.1016/S0828-282X(09)70043-1 |
0.506 |
|
| 2009 |
El-Haou S, Balse E, Neyroud N, Dilanian G, Gavillet B, Abriel H, Coulombe A, Jeromin A, Hatem SN. Kv4 potassium channels form a tripartite complex with the anchoring protein SAP97 and CaMKII in cardiac myocytes. Circulation Research. 104: 758-69. PMID 19213956 DOI: 10.1161/Circresaha.108.191007 |
0.847 |
|
| 2009 |
Albesa M, Rougier J, Abriel H, Viard P. G010 Regulation of voltage-dependent calcium channels by Nedd4-1 Archives of Cardiovascular Diseases. 102: S65. DOI: 10.1016/S1875-2136(09)72285-5 |
0.857 |
|
| 2009 |
Petitprez S, Zmoos A, Hatem S, Coulombe A, Abriel H. G009 Regulation of the cardiac sodium channel Nav1.5 by a member of MAGUK proteins: SAP97 Archives of Cardiovascular Diseases. 102: S65. DOI: 10.1016/S1875-2136(09)72284-3 |
0.862 |
|
| 2009 |
Sintra Grilo L, Pruvot E, Grobety M, Castella V, Fellmann F, Abriel H, Abriel H. G003 Characterization of a novel 7-amino-acid duplication located in the pas domain of hERG found in a patient with congenital long QT syndrome Archives of Cardiovascular Diseases. 102: S62-S63. DOI: 10.1016/S1875-2136(09)72278-8 |
0.55 |
|
| 2009 |
El-Haou S, Balse E, Neyroud N, Gavillet B, Abriel H, Coulombe A, Jeromin A, Hatem SN. The Anchoring Protein SAP97 Is Crucial For The Surface Expression Of Shal Kv Potassium Channels And Their Regulation By CaMKII In Cardiac Myocytes Biophysical Journal. 96: 261a. DOI: 10.1016/J.Bpj.2008.12.1291 |
0.844 |
|
| 2008 |
Petitprez S, Tiab L, Chen L, Kappeler L, Rösler KM, Schorderet D, Abriel H, Burgunder JM. A novel dominant mutation of the Nav1.4 alpha-subunit domain I leading to sodium channel myotonia. Neurology. 71: 1669-75. PMID 19015483 DOI: 10.1212/01.Wnl.0000335168.86248.55 |
0.822 |
|
| 2008 |
Petitprez S, Abriel H. Crosstalk between cardiac ion channel subunits: an encrypted language to be deciphered. Journal of Molecular and Cellular Cardiology. 45: 333-5. PMID 18582471 DOI: 10.1016/J.Yjmcc.2008.05.019 |
0.832 |
|
| 2008 |
Grilo LS, Abriel H. Male and female equality: still far from goal. The Journal of Physiology. 586: 2825-6. PMID 18556724 DOI: 10.1113/Jphysiol.2008.156398 |
0.802 |
|
| 2008 |
Petitprez S, Jespersen T, Pruvot E, Keller DI, Corbaz C, Schläpfer J, Abriel H, Kucera JP. Analyses of a novel SCN5A mutation (C1850S): conduction vs. repolarization disorder hypotheses in the Brugada syndrome. Cardiovascular Research. 78: 494-504. PMID 18252757 DOI: 10.1093/Cvr/Cvn023 |
0.834 |
|
| 2008 |
Petitprez S, Abriel H. Effects of heart failure on brain-type Na+ channels in rabbit ventricular myocytes. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 10: 257; author reply 25. PMID 18056137 DOI: 10.1093/Europace/Eum266 |
0.839 |
|
| 2008 |
Rougier JS, Muller O, Berger S, Centeno G, Schütz G, Firsov D, Abriel H. Mineralocorticoid receptor is essential for corticosteroid-induced up-regulation of L-type calcium currents in cultured neonatal cardiomyocytes. Pflã¼Gers Archiv : European Journal of Physiology. 456: 407-12. PMID 18040710 DOI: 10.1007/S00424-007-0387-Z |
0.722 |
|
| 2008 |
Eap C, Crettol S, Rougier J, Schläpfer J, Sintra Grilo L, Déglon J, Besson J, Croquette-Krokar M, Carrupt P, Abriel H. Stereoselective Block of hERG Channel by (S)-Methadone and QT Interval Prolongation in CYP2B6 Slow Metabolizer: Evidence of a Safer Cardiac Profile of (R)-Methadone Pharmacopsychiatry. 41. DOI: 10.1055/S-0028-1088244 |
0.464 |
|
| 2008 |
Crettol S, Schlaepfer J, Abriel H, Eap C. Response to “Methadone-Induced QTc Prolongation: Is it Due to Stereoselective Block of hERG or to Inappropriate QT Interval Correction?” Clinical Pharmacology & Therapeutics. 83: 672-672. DOI: 10.1038/Sj.Clpt.6100426 |
0.365 |
|
| 2007 |
Kranjcec D, Bergovec M, Rougier JS, Raguz M, Pavlovic S, Jespersen T, Castella V, Keller DI, Abriel H. Brugada syndrome unmasked by accidental inhalation of gasoline vapors. Pacing and Clinical Electrophysiology : Pace. 30: 1294-8. PMID 17897138 DOI: 10.1111/J.1540-8159.2007.00857.X |
0.723 |
|
| 2007 |
Abriel H. Roles and regulation of the cardiac sodium channel Na v 1.5: recent insights from experimental studies. Cardiovascular Research. 76: 381-9. PMID 17727828 DOI: 10.1016/J.Cardiores.2007.07.019 |
0.618 |
|
| 2007 |
Eap CB, Crettol S, Rougier JS, Schläpfer J, Sintra Grilo L, Déglon JJ, Besson J, Croquette-Krokar M, Carrupt PA, Abriel H. Stereoselective block of hERG channel by (S)-methadone and QT interval prolongation in CYP2B6 slow metabolizers. Clinical Pharmacology and Therapeutics. 81: 719-28. PMID 17329992 DOI: 10.1038/Sj.Clpt.6100120 |
0.462 |
|
| 2007 |
Jespersen T, Membrez M, Nicolas CS, Pitard B, Staub O, Olesen SP, Baró I, Abriel H. The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family. Cardiovascular Research. 74: 64-74. PMID 17289006 DOI: 10.1016/J.Cardiores.2007.01.008 |
0.618 |
|
| 2007 |
Domenighetti AA, Boixel C, Cefai D, Abriel H, Pedrazzini T. Chronic angiotensin II stimulation in the heart produces an acquired long QT syndrome associated with IK1 potassium current downregulation. Journal of Molecular and Cellular Cardiology. 42: 63-70. PMID 17070838 DOI: 10.1016/J.Yjmcc.2006.09.019 |
0.523 |
|
| 2006 |
Jespersen T, Gavillet B, van Bemmelen MX, Cordonier S, Thomas MA, Staub O, Abriel H. Cardiac sodium channel Na(v)1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1. Biochemical and Biophysical Research Communications. 348: 1455-62. PMID 16930557 DOI: 10.1016/J.Bbrc.2006.08.014 |
0.829 |
|
| 2006 |
Gavillet B, Rougier JS, Domenighetti AA, Behar R, Boixel C, Ruchat P, Lehr HA, Pedrazzini T, Abriel H. Cardiac sodium channel Nav1.5 is regulated by a multiprotein complex composed of syntrophins and dystrophin Circulation Research. 99: 407-414. PMID 16857961 DOI: 10.1161/01.Res.0000237466.13252.5E |
0.843 |
|
| 2006 |
Fodstad H, Bendahhou S, Rougier JS, Laitinen-Forsblom PJ, Barhanin J, Abriel H, Schild L, Kontula K, Swan H. Molecular characterization of two founder mutations causing long QT syndrome and identification of compound heterozygous patients. Annals of Medicine. 38: 294-304. PMID 16754261 DOI: 10.1080/07853890600756065 |
0.706 |
|
| 2006 |
Camacho JA, Hensellek S, Rougier JS, Blechschmidt S, Abriel H, Benndorf K, Zimmer T. Modulation of Nav1.5 channel function by an alternatively spliced sequence in the DII/DIII linker region. The Journal of Biological Chemistry. 281: 9498-506. PMID 16469732 DOI: 10.1074/Jbc.M509716200 |
0.782 |
|
| 2006 |
Boixel C, Gavillet B, Rougier JS, Abriel H. Aldosterone increases voltage-gated sodium current in ventricular myocytes. American Journal of Physiology. Heart and Circulatory Physiology. 290: H2257-66. PMID 16428353 DOI: 10.1152/Ajpheart.01060.2005 |
0.841 |
|
| 2005 |
Abriel H, Staub O. Ubiquitylation of ion channels. Physiology (Bethesda, Md.). 20: 398-407. PMID 16287989 DOI: 10.1152/Physiol.00033.2005 |
0.564 |
|
| 2005 |
Keller DI, Rougier JS, Kucera JP, Benammar N, Fressart V, Guicheney P, Madle A, Fromer M, Schläpfer J, Abriel H. Brugada syndrome and fever: genetic and molecular characterization of patients carrying SCN5A mutations. Cardiovascular Research. 67: 510-9. PMID 15890323 DOI: 10.1016/J.Cardiores.2005.03.024 |
0.765 |
|
| 2005 |
Abriel H, Kass RS. Regulation of the voltage-gated cardiac sodium channel Nav1.5 by interacting proteins. Trends in Cardiovascular Medicine. 15: 35-40. PMID 15795161 DOI: 10.1016/J.Tcm.2005.01.001 |
0.745 |
|
| 2005 |
Rougier JS, van Bemmelen MX, Bruce MC, Jespersen T, Gavillet B, Apothéloz F, Cordonier S, Staub O, Rotin D, Abriel H. Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins. American Journal of Physiology. Cell Physiology. 288: C692-701. PMID 15548568 DOI: 10.1152/Ajpcell.00460.2004 |
0.831 |
|
| 2004 |
Abriel H, Schläpfer J, Keller DI, Gavillet B, Buclin T, Biollaz J, Stoller R, Kappenberger L. Molecular and clinical determinants of drug-induced long QT syndrome: an iatrogenic channelopathy. Swiss Medical Weekly. 134: 685-94. PMID 15616901 DOI: 10.4414/Smw.2004.10532 |
0.756 |
|
| 2004 |
Le Bouter S, El Harchi A, Marionneau C, Bellocq C, Chambellan A, van Veen T, Boixel C, Gavillet B, Abriel H, Le Quang K, Chevalier JC, Lande G, Léger JJ, Charpentier F, Escande D, et al. Long-term amiodarone administration remodels expression of ion channel transcripts in the mouse heart. Circulation. 110: 3028-35. PMID 15520326 DOI: 10.1161/01.Cir.0000147187.78162.Ac |
0.816 |
|
| 2004 |
van Bemmelen MX, Rougier JS, Gavillet B, Apothéloz F, Daidié D, Tateyama M, Rivolta I, Thomas MA, Kass RS, Staub O, Abriel H. Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination. Circulation Research. 95: 284-91. PMID 15217910 DOI: 10.1161/01.Res.0000136816.05109.89 |
0.851 |
|
| 2004 |
Blot V, Perugi F, Gay B, Prévost MC, Briant L, Tangy F, Abriel H, Staub O, Dokhélar MC, Pique C. Nedd4.1-mediated ubiquitination and subsequent recruitment of Tsg101 ensure HTLV-1 Gag trafficking towards the multivesicular body pathway prior to virus budding. Journal of Cell Science. 117: 2357-67. PMID 15126635 DOI: 10.1242/Jcs.01095 |
0.413 |
|
| 2002 |
Liu H, Tateyama M, Clancy CE, Abriel H, Kass RS. Channel openings are necessary but not sufficient for use-dependent block of cardiac Na(+) channels by flecainide: evidence from the analysis of disease-linked mutations. The Journal of General Physiology. 120: 39-51. PMID 12084774 DOI: 10.1085/Jgp.20028558 |
0.742 |
|
| 2001 |
Rivolta I, Abriel H, Tateyama M, Liu H, Memmi M, Vardas P, Napolitano C, Priori SG, Kass RS. Inherited Brugada and long QT-3 syndrome mutations of a single residue of the cardiac sodium channel confer distinct channel and clinical phenotypes. The Journal of Biological Chemistry. 276: 30623-30. PMID 11410597 DOI: 10.1074/Jbc.M104471200 |
0.74 |
|
| 2001 |
Kurokawa J, Abriel H, Kass RS. Molecular basis of the delayed rectifier current I(ks)in heart. Journal of Molecular and Cellular Cardiology. 33: 873-82. PMID 11343411 DOI: 10.1006/Jmcc.2001.1377 |
0.794 |
|
| 2001 |
Abriel H, Cabo C, Wehrens XH, Rivolta I, Motoike HK, Memmi M, Napolitano C, Priori SG, Kass RS. Novel arrhythmogenic mechanism revealed by a long-QT syndrome mutation in the cardiac Na(+) channel. Circulation Research. 88: 740-5. PMID 11304498 DOI: 10.1161/Hh0701.089668 |
0.755 |
|
| 2001 |
Dhar Malhotra J, Chen C, Rivolta I, Abriel H, Malhotra R, Mattei LN, Brosius FC, Kass RS, Isom LL. Characterization of sodium channel alpha- and beta-subunits in rat and mouse cardiac myocytes. Circulation. 103: 1303-10. PMID 11238277 DOI: 10.1161/01.Cir.103.9.1303 |
0.637 |
|
| 2000 |
Abriel H, Wehrens XH, Benhorin J, Kerem B, Kass RS. Molecular pharmacology of the sodium channel mutation D1790G linked to the long-QT syndrome. Circulation. 102: 921-5. PMID 10952963 DOI: 10.1161/01.Cir.102.8.921 |
0.73 |
|
| 2000 |
Wehrens XH, Abriel H, Cabo C, Benhorin J, Kass RS. Arrhythmogenic mechanism of an LQT-3 mutation of the human heart Na(+) channel alpha-subunit: A computational analysis. Circulation. 102: 584-90. PMID 10920073 DOI: 10.1161/01.Cir.102.5.584 |
0.753 |
|
| 2000 |
Abriel H, Motoike H, Kass RS. KChAP: a novel chaperone for specific K(+) channels key to repolarization of the cardiac action potential. Focus on "KChAP as a chaperone for specific K(+) channels". American Journal of Physiology. Cell Physiology. 278: C863-4. PMID 10794658 DOI: 10.1152/Ajpcell.2000.278.5.C863 |
0.71 |
|
| 2000 |
Staub O, Abriel H, Plant P, Ishikawa T, Kanelis V, Saleki R, Horisberger JD, Schild L, Rotin D. Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination. Kidney International. 57: 809-15. PMID 10720933 DOI: 10.1046/J.1523-1755.2000.00919.X |
0.556 |
|
| 2000 |
Abriel H, Kamynina E, Horisberger JD, Staub O. Regulation of the cardiac voltage-gated Na+ channel (H1) by the ubiquitin-protein ligase Nedd4. Febs Letters. 466: 377-80. PMID 10682864 DOI: 10.1016/S0014-5793(00)01098-X |
0.639 |
|
| 1999 |
Abriel H, Hasler U, Geering K, Horisberger JD. Role of the intracellular domain of the beta subunit in Na,K pump function. Biochimica Et Biophysica Acta. 1418: 85-96. PMID 10209213 DOI: 10.1016/S0005-2736(99)00025-5 |
0.415 |
|
| 1999 |
Abriel H, Loffing J, Rebhun JF, Pratt JH, Schild L, Horisberger JD, Rotin D, Staub O. Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome. The Journal of Clinical Investigation. 103: 667-73. PMID 10074483 DOI: 10.1172/Jci5713 |
0.568 |
|
| 1999 |
Abriel H, Horisberger JD. Feedback inhibition of rat amiloride-sensitive epithelial sodium channels expressed in Xenopus laevis oocytes. The Journal of Physiology. 31-43. PMID 10066920 DOI: 10.1111/J.1469-7793.1999.031Aa.X |
0.51 |
|
| 1995 |
Abriel H, Katz U, Kucera P. Ion transport across the early chick embryo: II. Characterization and pH sensitivity of the transembryonic short-circuit current. The Journal of Membrane Biology. 141: 159-66. PMID 7807518 DOI: 10.1007/Bf00238249 |
0.481 |
|
| 1995 |
Kucera P, Abriel H, Katz U. Ion transport across the early chick embryo: I. Electrical measurements, ionic fluxes and regional heterogeneity. The Journal of Membrane Biology. 141: 149-57. PMID 7807517 DOI: 10.1007/Bf00238248 |
0.409 |
|
| 1992 |
Schlumpf M, Parmar R, Schreiber A, Ramseier H, Bütikofer E, Abriel H, Barth M, Rhymer T, Lichtensteiger W. Nervous and Immune Systems as
Targets for Developmental
Effects of Benzodiazepines Developmental Pharmacology and Therapeutics. 18: 145-158. DOI: 10.1159/000480614 |
0.365 |
|
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