Peter M. Grace, BHSc (Hons), PhD (Med) - Publications

Affiliations: 
Discipline of Pharmacology University of Adelaide, Adelaide, South Australia, Australia 
 Psychology and Neuroscience University of Colorado, Boulder, Boulder, CO, United States 
 2006-2011 Discipline of Pharmacology University of Adelaide, Adelaide, South Australia, Australia 
 2016- Critical Care Research University of Texas M.D. Anderson Cancer Center 
Area:
Neuroimmunopharmacology, Neuroscience, Immunology, Pharmacology

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Green-Fulgham SM, Harland ME, Ball JB, Li J, Lacagnina MJ, D'Angelo H, Dreher RA, Willcox KF, Lorca SA, Kwilasz AJ, Maier SF, Watkins LR, Grace PM. Preconditioning by voluntary wheel running attenuates later neuropathic pain via Nrf2 antioxidant signaling in rats. Pain. PMID 35486864 DOI: 10.1097/j.pain.0000000000002589  0.842
2022 Li J, Stratton HJ, Lorca SA, Grace PM, Khanna R. Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in chronic constriction injury (CCI) rats. Channels (Austin, Tex.). 16: 1-8. PMID 34983286 DOI: 10.1080/19336950.2021.2023383  0.765
2021 Cata JP, Patiño M, Lacagnina MJ, Li J, Gorur A, Agudelo-Jimenez R, Wei B, Hagberg CA, Dougherty PM, Shureiqi I, Yang P, Grace PM. A rat model to investigate quality of recovery after abdominal surgery. Pain Reports. 6: e943. PMID 34235345 DOI: 10.1097/PR9.0000000000000943  0.756
2021 Lacagnina MJ, Heijnen CJ, Watkins LR, Grace PM. Autoimmune regulation of chronic pain. Pain Reports. 6: e905. PMID 33981931 DOI: 10.1097/PR9.0000000000000905  0.839
2021 Hoogendoorn A, Avery TD, Li J, Bursill C, Abell A, Grace PM. Emerging Therapeutic Applications for Fumarates. Trends in Pharmacological Sciences. PMID 33618840 DOI: 10.1016/j.tips.2021.01.004  0.606
2021 Mai CL, Tan Z, Xu YN, Zhang JJ, Huang ZH, Wang D, Zhang H, Gui WS, Zhang J, Lin ZJ, Meng YT, Wei X, Jie YT, Grace PM, Wu LJ, et al. CXCL12-mediated monocyte transmigration into brain perivascular space leads to neuroinflammation and memory deficit in neuropathic pain. Theranostics. 11: 1059-1078. PMID 33391521 DOI: 10.7150/thno.44364  0.369
2020 Muscat SM, Deems NP, D'Angelo H, Kitt MM, Grace PM, Andersen ND, Silverman SN, Rice KC, Watkins LR, Maier SF, Barrientos RM. Postoperative cognitive dysfunction is made persistent with morphine treatment in aged rats. Neurobiology of Aging. 98: 214-224. PMID 33341652 DOI: 10.1016/j.neurobiolaging.2020.11.008  0.589
2020 Grace PM, Tawfik VL, Svensson CI, Burton MD, Loggia ML, Hutchinson MR. The Neuroimmunology of Chronic Pain: From Rodents to Humans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33239404 DOI: 10.1523/JNEUROSCI.1650-20.2020  0.758
2020 Lacagnina MJ, Li J, Lorca S, Rice KC, Sullivan K, O'Callaghan JP, Grace PM. A role for neuroimmune signaling in a rat model of Gulf War Illness-related pain. Brain, Behavior, and Immunity. PMID 33127584 DOI: 10.1016/j.bbi.2020.10.022  0.84
2020 Green-Fulgham SM, Ball JB, Maier SF, Rice KC, Watkins LR, Grace PM. Suppression of active phase voluntary wheel running in male rats by unilateral chronic constriction injury: Enduring therapeutic effects of a brief treatment of morphine combined with TLR4 or P2X7 antagonists. Journal of Neuroscience Research. PMID 32533604 DOI: 10.1002/Jnr.24645  0.692
2020 Doyle TM, Janes K, Chen Z, Grace PM, Esposito E, Cuzzocrea S, Largent-Milnes TM, Neumann WL, Watkins LR, Spiegel S, Vanderah TW, Salvemini D. Activation of sphingosine-1-phosphate receptor subtype 1 in the central nervous system contributes to morphine-induced hyperalgesia and antinociceptive tolerance in rodents. Pain. PMID 32301840 DOI: 10.1097/J.Pain.0000000000001888  0.71
2020 Li J, Ma J, Lacagnina MJ, Lorca S, Odem MA, Walters ET, Kavelaars A, Grace PM. Oral Dimethyl Fumarate Reduces Peripheral Neuropathic Pain in Rodents via NFE2L2 Antioxidant Signaling. Anesthesiology. 132: 343-356. PMID 31939850 DOI: 10.1097/Aln.0000000000003077  0.84
2019 Li J, Ma J, Lacagnina MJ, Lorca S, Odem MA, Walters ET, Kavelaars A, Grace PM. Oral Dimethyl Fumarate Reduces Peripheral Neuropathic Pain in Rodents via NFE2L2 Antioxidant Signaling. Anesthesiology. PMID 31841447 DOI: 10.1097/ALN.0000000000003077  0.84
2019 Peng Y, Zhang X, Zhang T, Grace PM, Li H, Wang Y, Li H, Chen H, Watkins LR, Hutchinson MR, Yin H, Wang X. Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain. Brain, Behavior, and Immunity. PMID 31542403 DOI: 10.1016/J.Bbi.2019.09.013  0.806
2019 Odem MA, Lacagnina MJ, Katzen SL, Li J, Spence EA, Grace PM, Walters ET. Sham surgeries for central and peripheral neural injuries persistently enhance pain-avoidance behavior as revealed by an operant conflict test. Pain. PMID 31323014 DOI: 10.1097/J.Pain.0000000000001642  0.844
2019 Green-Fulgham SM, Ball JB, Kwilasz AJ, Fabisiak T, Maier SF, Watkins LR, Grace PM. Oxycodone, fentanyl, and morphine amplify established neuropathic pain in male rats. Pain. PMID 31299018 DOI: 10.1097/J.Pain.0000000000001652  0.719
2019 Zhang X, Peng Y, Grace PM, Metcalf MD, Kwilasz AJ, Wang Y, Zhang T, Wu S, Selfridge BR, Portoghese PS, Rice KC, Watkins LR, Hutchinson MR, Wang X. Stereochemistry and innate immune recognition: (+)-norbinaltorphimine targets myeloid differentiation protein 2 and inhibits toll-like receptor 4 signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900173RRR. PMID 31162938 DOI: 10.1096/Fj.201900173Rrr  0.752
2019 Ball J, Green-Fulgham S, Watkins L, Grace P. (351) The Opioids Oxycodone, Fentanyl, and Morphine Amplify Neuropathic when Given after Chronic Pain is Established The Journal of Pain. 20: S62. DOI: 10.1016/J.Jpain.2019.02.047  0.752
2018 Grace PM, Strand KA, Galer EL, Maier SF, Watkins LR. MicroRNA-124 and microRNA-146a both attenuate persistent neuropathic pain induced by morphine in male rats. Brain Research. PMID 29723521 DOI: 10.1016/J.Brainres.2018.04.038  0.625
2018 Grace PM, Galer EL, Strand KA, Corrigan K, Berkelhammer D, Maier SF, Watkins LR. Repeated Morphine Prolongs Postoperative Pain in Male Rats. Anesthesia and Analgesia. PMID 29596097 DOI: 10.1213/Ane.0000000000003345  0.757
2018 Grace PM, Wang X, Strand KA, Baratta MV, Zhang Y, Galer EL, Yin H, Maier SF, Watkins LR. DREADDed microglia in pain: Implications for spinal inflammatory signaling in male rats. Experimental Neurology. PMID 29530713 DOI: 10.1016/J.Expneurol.2018.03.005  0.696
2017 Lacagnina MJ, Watkins LR, Grace PM. Toll-like receptors and their role in persistent pain. Pharmacology & Therapeutics. PMID 28987324 DOI: 10.1016/J.Pharmthera.2017.10.006  0.855
2017 Grace PM, Strand KA, Galer EL, Rice KC, Maier SF, Watkins LR. Protraction of neuropathic pain by morphine is mediated by spinal damage associated molecular patterns (DAMPs) in male rats. Brain, Behavior, and Immunity. PMID 28860068 DOI: 10.1016/J.Bbi.2017.08.018  0.689
2017 Lacagnina MJ, Kopec AM, Cox SS, Hanamsagar R, Wells C, Slade S, Grace PM, Watkins LR, Levin ED, Bilbo SD. Opioid Self-Administration is Attenuated by Early-Life Experience and Gene Therapy for Anti-Inflammatory IL-10 in the Nucleus Accumbens of Male Rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28436446 DOI: 10.1038/Npp.2017.82  0.777
2017 McDonnell B, Kullmann A, Wolf-Johnston A, Kanai A, Grace P, Watkins L, Rodriguez L, Birder L. Pd01-03 Stress-Induced Adrenergic Dysregulation Alters Neural-Glial Distribution And Phenotype The Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.183  0.532
2017 Lacagnina M, Fabisiak T, Grace P. Mapping microglial reactivity in the brain after sciatic nerve injury Brain, Behavior, and Immunity. 66: e16. DOI: 10.1016/J.Bbi.2017.07.068  0.802
2016 Grace P, Strand K, Galer E, Anderson N, Fabisiak T, Fulgham S, Greenwood B, Fleshner M, Maier S, Watkins L. (464) Prior voluntary wheel running is protective for neuropathic-like pain. The Journal of Pain : Official Journal of the American Pain Society. 17: S90. PMID 28162718 DOI: 10.1016/J.Jpain.2016.01.441  0.738
2016 Lewis SS, Grace PM, Hutchinson MR, Maier SF, Watkins LR. Constriction of the buccal branch of the facial nerve produces unilateral craniofacial allodynia. Brain, Behavior, and Immunity. PMID 27993689 DOI: 10.1016/J.Bbi.2016.12.004  0.829
2016 Grace PM, Gaudet AD, Staikopoulos V, Maier SF, Hutchinson MR, Salvemini D, Watkins LR. Nitroxidative Signaling Mechanisms in Pathological Pain. Trends in Neurosciences. PMID 27842920 DOI: 10.1016/J.Tins.2016.10.003  0.824
2016 Das N, Dewan V, Grace PM, Gunn RJ, Tamura R, Tzarum N, Watkins LR, Wilson IA, Yin H. HMGB1 Activates Proinflammatory Signaling via TLR5 Leading to Allodynia. Cell Reports. 17: 1128-1140. PMID 27760316 DOI: 10.1016/J.Celrep.2016.09.076  0.666
2016 Dodds KN, Beckett EA, Evans SF, Grace PM, Watkins LR, Hutchinson MR. Glial contributions to visceral pain: implications for disease etiology and the female predominance of persistent pain. Translational Psychiatry. 6: e888. PMID 27622932 DOI: 10.1038/Tp.2016.168  0.828
2016 Ellis A, Grace PM, Wieseler J, Favret J, Springer K, Skarda B, Hutchinson MR, Falci S, Rice KC, Maier SF, Watkins LR. Morphine amplifies mechanical allodynia via TLR4 in a rat model of spinal cord injury. Brain, Behavior, and Immunity. PMID 27519154 DOI: 10.1016/J.Bbi.2016.08.004  0.825
2016 Grace PM, Fabisiak TJ, Green-Fulgham SM, Anderson ND, Strand KA, Kwilasz AJ, Galer EL, Walker FR, Greenwood BN, Maier SF, Fleshner M, Watkins LR. Prior voluntary wheel running attenuates neuropathic pain. Pain. PMID 27355182 DOI: 10.1097/J.Pain.0000000000000607  0.709
2016 Mashaghi A, Marmalidou A, Tehrani M, Grace PM, Pothoulakis C, Dana R. Neuropeptide substance P and the immune response. Cellular and Molecular Life Sciences : Cmls. PMID 27314883 DOI: 10.1007/S00018-016-2293-Z  0.303
2016 Grace PM, Strand KA, Galer EL, Urban DJ, Wang X, Baratta MV, Fabisiak TJ, Anderson ND, Cheng K, Greene LI, Berkelhammer D, Zhang Y, Ellis AL, Yin HH, Campeau S, et al. Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27247388 DOI: 10.1073/Pnas.1602070113  0.853
2016 Grace PM, Loram LC, Christianson JP, Strand KA, Flyer-Adams JG, Penzkover KR, Forsayeth JR, Dam AV, Mahoney MJ, Maier SF, Chavez RA, Watkins LR. Behavioral assessment of neuropathic pain, fatigue, and anxiety in experimental autoimmune encephalomyelitis (EAE) and attenuation by interleukin-10 gene therapy. Brain, Behavior, and Immunity. PMID 27189037 DOI: 10.1016/J.Bbi.2016.05.012  0.649
2015 Galer EL, Grace PM. Reactive aldehydes: a new player in inflammatory pain. Annals of Translational Medicine. 3: S23. PMID 26046069 DOI: 10.3978/J.Issn.2305-5839.2015.03.27  0.54
2015 Selfridge BR, Wang X, Zhang Y, Yin H, Grace PM, Watkins LR, Jacobson AE, Rice KC. Structure-Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists. Journal of Medicinal Chemistry. 58: 5038-52. PMID 26010811 DOI: 10.1021/Acs.Jmedchem.5B00426  0.659
2015 Grace PM, Maier SF, Watkins LR. Opioid-induced central immune signaling: implications for opioid analgesia. Headache. 55: 475-89. PMID 25833219 DOI: 10.1111/Head.12552  0.673
2015 Grace PM, Shimizu K, Strand KA, Rice KC, Deng G, Watkins LR, Herson PS. (+)-Naltrexone is neuroprotective and promotes alternative activation in the mouse hippocampus after cardiac arrest/cardiopulmonary resuscitation. Brain, Behavior, and Immunity. 48: 115-22. PMID 25774010 DOI: 10.1016/J.Bbi.2015.03.005  0.564
2015 Griggs RB, Donahue RR, Morgenweck J, Grace PM, Sutton A, Watkins LR, Taylor BK. Pioglitazone rapidly reduces neuropathic pain through astrocyte and nongenomic PPARγ mechanisms. Pain. 156: 469-82. PMID 25599238 DOI: 10.1097/01.J.Pain.0000460333.79127.Be  0.723
2015 Kwilasz AJ, Grace PM, Serbedzija P, Maier SF, Watkins LR. The therapeutic potential of interleukin-10 in neuroimmune diseases. Neuropharmacology. 96: 55-69. PMID 25446571 DOI: 10.1016/J.Neuropharm.2014.10.020  0.618
2015 Grace P, Wang X, Urban D, Baratta M, Galer E, Strand K, Zhang Y, Yin H, Roth B, Maier S, Watkins L. (250) Selective manipulation of spinal microglia by chemogenetics: implications for allodynia and inflammatory signaling The Journal of Pain. 16: S38. DOI: 10.1016/J.Jpain.2015.01.167  0.605
2015 Grace P, Wang X, Urban D, Baratta M, Galer E, Strand K, Zhang Y, Yin H, Roth B, Maier S, Watkins L. Selective manipulation of spinal microglia by chemogenetics: Implications for allodynia and inflammatory signaling Brain, Behavior, and Immunity. 49: e7. DOI: 10.1016/J.Bbi.2015.06.045  0.685
2014 Grace PM, Ramos KM, Rodgers KM, Wang X, Hutchinson MR, Lewis MT, Morgan KN, Kroll JL, Taylor FR, Strand KA, Zhang Y, Berkelhammer D, Huey MG, Greene LI, Cochran TA, et al. Activation of adult rat CNS endothelial cells by opioid-induced toll-like receptor 4 (TLR4) signaling induces proinflammatory, biochemical, morphological, and behavioral sequelae. Neuroscience. 280: 299-317. PMID 25241065 DOI: 10.1016/J.Neuroscience.2014.09.020  0.756
2014 Nicotra L, Tuke J, Grace PM, Rolan PE, Hutchinson MR. Sex differences in mechanical allodynia: how can it be preclinically quantified and analyzed? Frontiers in Behavioral Neuroscience. 8: 40. PMID 24592221 DOI: 10.3389/Fnbeh.2014.00040  0.823
2014 Grace PM, Hutchinson MR, Maier SF, Watkins LR. Pathological pain and the neuroimmune interface. Nature Reviews. Immunology. 14: 217-31. PMID 24577438 DOI: 10.1038/Nri3621  0.821
2014 Narayan DS, Casson RJ, Ebneter A, Chidlow G, Grace PM, Hutchinson MR, Wood JP. Immune priming and experimental glaucoma: the effect of prior systemic lipopolysaccharide challenge on tissue outcomes after optic nerve injury. Clinical & Experimental Ophthalmology. 42: 539-54. PMID 24373007 DOI: 10.1111/Ceo.12289  0.651
2014 Grace PM, Strand KA, Maier SF, Watkins LR. Suppression of voluntary wheel running in rats is dependent on the site of inflammation: evidence for voluntary running as a measure of hind paw-evoked pain. The Journal of Pain : Official Journal of the American Pain Society. 15: 121-8. PMID 24287315 DOI: 10.1016/J.Jpain.2013.10.001  0.731
2014 Grace P, Strand K, Galer E, Zhang Y, Greene L, Rice K, Maier S, Watkins L. (299) Therapeutic morphine prolongs neuropathic pain in Fischer 344 rats: a role for TLR4 and inflammasome signaling in the lumbar spinal cord The Journal of Pain. 15: S50. DOI: 10.1016/J.Jpain.2014.01.209  0.722
2014 Grace P, Strand K, Galer E, Zhang Y, Berkelhammer D, Greene L, Rice K, Maier S, Watkins L. 31. Therapeutic morphine prolongs neuropathic pain in rats: A role for TLR4 and inflammasome signaling in the lumbar spinal cord Brain, Behavior, and Immunity. 40: e9-e10. DOI: 10.1016/J.Bbi.2014.06.051  0.711
2013 Kwok YH, Tuke J, Nicotra LL, Grace PM, Rolan PE, Hutchinson MR. TLR 2 and 4 responsiveness from isolated peripheral blood mononuclear cells from rats and humans as potential chronic pain biomarkers. Plos One. 8: e77799. PMID 24204973 DOI: 10.1371/Journal.Pone.0077799  0.849
2013 Wang X, Grace PM, Pham MN, Cheng K, Strand KA, Smith C, Li J, Watkins LR, Yin H. Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 2713-22. PMID 23568774 DOI: 10.1096/Fj.12-222992  0.697
2013 Grace P, Greene L, Strand K, Rice K, Maier S, Watkins L. 18. Repeated morphine enhances peripheral nerve injury-induced allodynia via central immune mechanisms Brain, Behavior, and Immunity. 32: e5-e6. DOI: 10.1016/J.Bbi.2013.07.030  0.661
2012 Grace PM. The anatomical distribution of trigeminal neuralgia: a perspective and future directions. Anesthesiology and Pain Medicine. 1: 212-3. PMID 24904801 DOI: 10.5812/Kowsar.22287523.3641  0.506
2012 Loram LC, Grace PM, Strand KA, Taylor FR, Ellis A, Berkelhammer D, Bowlin M, Skarda B, Maier SF, Watkins LR. Prior exposure to repeated morphine potentiates mechanical allodynia induced by peripheral inflammation and neuropathy. Brain, Behavior, and Immunity. 26: 1256-64. PMID 22902523 DOI: 10.1016/J.Bbi.2012.08.003  0.803
2012 Grace PM, Hurley D, Barratt DT, Tsykin A, Watkins LR, Rolan PE, Hutchinson MR. Harnessing pain heterogeneity and RNA transcriptome to identify blood-based pain biomarkers: a novel correlational study design and bioinformatics approach in a graded chronic constriction injury model. Journal of Neurochemistry. 122: 976-94. PMID 22697386 DOI: 10.1111/J.1471-4159.2012.07833.X  0.842
2011 Hutchinson MR, Shavit Y, Grace PM, Rice KC, Maier SF, Watkins LR. Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia. Pharmacological Reviews. 63: 772-810. PMID 21752874 DOI: 10.1124/Pr.110.004135  0.785
2011 Grace PM, Rolan PE, Hutchinson MR. Peripheral immune contributions to the maintenance of central glial activation underlying neuropathic pain. Brain, Behavior, and Immunity. 25: 1322-32. PMID 21496480 DOI: 10.1016/J.Bbi.2011.04.003  0.817
2011 Grace PM, Hutchinson MR, Bishop A, Somogyi AA, Mayrhofer G, Rolan PE. Adoptive transfer of peripheral immune cells potentiates allodynia in a graded chronic constriction injury model of neuropathic pain. Brain, Behavior, and Immunity. 25: 503-13. PMID 21134441 DOI: 10.1016/J.Bbi.2010.11.018  0.845
2011 Grace P, Rolan P, Hutchinson M. Harnessing pain heterogeneity and RNA transcriptome to explore chronic pain mechanisms Brain, Behavior, and Immunity. 25: S193-S194. DOI: 10.1016/J.Bbi.2011.07.055  0.812
2010 Grace PM, Hutchinson MR, Manavis J, Somogyi AA, Rolan PE. A novel animal model of graded neuropathic pain: utility to investigate mechanisms of population heterogeneity. Journal of Neuroscience Methods. 193: 47-53. PMID 20817038 DOI: 10.1016/J.Jneumeth.2010.08.025  0.851
2010 Grace PM, Stanford T, Gentgall M, Rolan PE. Utility of saccadic eye movement analysis as an objective biomarker to detect the sedative interaction between opioids and sleep deprivation in opioid-naive and opioid-tolerant populations. Journal of Psychopharmacology (Oxford, England). 24: 1631-40. PMID 20142307 DOI: 10.1177/0269881109352704  0.574
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