| Year |
Citation |
Score |
| 2023 |
Hipke K, Pitter B, Hruscha A, van Bebber F, Modic M, Bansal V, Lewandowski SA, Orozco D, Edbauer D, Bonn S, Haass C, Pohl U, Montanez E, Schmid B. Loss of TDP-43 causes ectopic endothelial sprouting and migration defects through increased , and . Frontiers in Cell and Developmental Biology. 11: 1169962. PMID 37384248 DOI: 10.3389/fcell.2023.1169962 |
0.438 |
|
| 2022 |
Riemenschneider H, Guo Q, Bader J, Frottin F, Farny D, Kleinberger G, Haass C, Mann M, Hartl FU, Baumeister W, Hipp MS, Meissner F, Fernández-Busnadiego R, Edbauer D. Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons. Embo Reports. e53890. PMID 35438230 DOI: 10.15252/embr.202153890 |
0.535 |
|
| 2022 |
Gruijs da Silva LA, Simonetti F, Hutten S, Riemenschneider H, Sternburg EL, Pietrek LM, Gebel J, Dötsch V, Edbauer D, Hummer G, Stelzl LS, Dormann D. Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation. The Embo Journal. e108443. PMID 35112738 DOI: 10.15252/embj.2021108443 |
0.317 |
|
| 2021 |
Mori K, Gotoh S, Yamashita T, Uozumi R, Kawabe Y, Tagami S, Kamp F, Nuscher B, Edbauer D, Haass C, Nagai Y, Ikeda M. The porphyrin TMPyP4 inhibits elongation during the non-canonical translation of the FTLD/ALS-associated GGGGCC repeat in the C9orf72 gene. The Journal of Biological Chemistry. 101120. PMID 34450161 DOI: 10.1016/j.jbc.2021.101120 |
0.447 |
|
| 2021 |
Nuebling GS, Prix C, Brendel M, Beyer L, Wlasich E, Loosli SV, Barthel H, Sabri O, Bartenstein P, Vöglein J, Danek A, Rominger A, Edbauer D, Haass C, Levin J. Low-degree trisomy 21 mosaicism promotes early-onset Alzheimer disease. Neurobiology of Aging. PMID 33789815 DOI: 10.1016/j.neurobiolaging.2021.02.021 |
0.432 |
|
| 2020 |
Werner G, Damme M, Schludi M, Gnörich J, Wind K, Fellerer K, Wefers B, Wurst W, Edbauer D, Brendel M, Haass C, Capell A. Loss of TMEM106B potentiates lysosomal and FTLD-like pathology in progranulin-deficient mice. Embo Reports. e50241. PMID 32929860 DOI: 10.15252/Embr.202050241 |
0.466 |
|
| 2019 |
Zhou Q, Mareljic N, Michaelsen M, Parhizkar S, Heindl S, Nuscher B, Farny D, Czuppa M, Schludi C, Graf A, Krebs S, Blum H, Feederle R, Roth S, Haass C, ... ... Edbauer D, et al. Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model. Embo Molecular Medicine. e10919. PMID 31858749 DOI: 10.15252/Emmm.201910919 |
0.376 |
|
| 2019 |
Nihei Y, Mori K, Werner G, Arzberger T, Zhou Q, Khosravi B, Japtok J, Hermann A, Sommacal A, Weber M, Kamp F, Nuscher B, Edbauer D, et al. Poly-glycine-alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3. Acta Neuropathologica. PMID 31642962 DOI: 10.1007/S00401-019-02082-0 |
0.428 |
|
| 2019 |
Parhizkar S, Arzberger T, Brendel M, Kleinberger G, Deussing M, Focke C, Nuscher B, Xiong M, Ghasemigharagoz A, Katzmarski N, Krasemann S, Lichtenthaler SF, Müller SA, Colombo A, Monasor LS, ... ... Edbauer D, et al. Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE. Nature Neuroscience. PMID 30617257 DOI: 10.1038/S41593-018-0296-9 |
0.45 |
|
| 2017 |
Zhou Q, Lehmer C, Michaelsen M, Mori K, Alterauge D, Baumjohann D, Schludi MH, Greiling J, Farny D, Flatley A, Feederle R, May S, Schreiber F, Arzberger T, Kuhm C, ... ... Edbauer D, et al. Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins. Embo Molecular Medicine. PMID 28351931 DOI: 10.15252/Emmm.201607054 |
0.462 |
|
| 2017 |
Ohki Y, Wenninger-Weinzierl A, Hruscha A, Asakawa K, Kawakami K, Haass C, Edbauer D, Schmid B. Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration. Molecular Neurodegeneration. 12: 6. PMID 28088213 DOI: 10.1186/S13024-016-0146-8 |
0.485 |
|
| 2016 |
Mori K, Nihei Y, Arzberger T, Zhou Q, Mackenzie IR, Hermann A, Hanisch F, Kamp F, Nuscher B, Orozco D, Edbauer D, Haass C. Reduced hnRNPA3 increases C9orf72 repeat RNA levels and dipeptide-repeat protein deposition. Embo Reports. PMID 27461252 DOI: 10.15252/Embr.201541724 |
0.452 |
|
| 2016 |
Suárez-Calvet M, Neumann M, Arzberger T, Abou-Ajram C, Funk E, Hartmann H, Edbauer D, Kremmer E, Göbl C, Resch M, Bourgeois B, Madl T, Reber S, Jutzi D, Ruepp MD, et al. Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS. Acta Neuropathologica. PMID 26895297 DOI: 10.1007/S00401-016-1544-2 |
0.448 |
|
| 2015 |
Fleck D, Voss M, Brankatschk B, Giudici C, Hampel H, Schwenk B, Edbauer D, Fukumori A, Steiner H, Kremmer E, Haug-Kröeper M, Rossner MJ, Fluhrer R, Willem M, Haass C. Proteolytic processing of Neuregulin 1 type III by three intramembrane cleaving proteases. The Journal of Biological Chemistry. PMID 26574544 DOI: 10.1074/Jbc.M115.697995 |
0.463 |
|
| 2015 |
Edbauer D, Haass C. An amyloid-like cascade hypothesis for C9orf72 ALS/FTD. Current Opinion in Neurobiology. 36: 99-106. PMID 26555807 DOI: 10.1016/J.Conb.2015.10.009 |
0.487 |
|
| 2014 |
Schwenk BM, Lang CM, Hogl S, Tahirovic S, Orozco D, Rentzsch K, Lichtenthaler SF, Hoogenraad CC, Capell A, Haass C, Edbauer D. The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes. The Embo Journal. 33: 450-67. PMID 24357581 DOI: 10.1002/Embj.201385857 |
0.4 |
|
| 2013 |
Mori K, Arzberger T, Grässer FA, Gijselinck I, May S, Rentzsch K, Weng SM, Schludi MH, van der Zee J, Cruts M, Van Broeckhoven C, Kremmer E, Kretzschmar HA, Haass C, Edbauer D. Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins. Acta Neuropathologica. 126: 881-93. PMID 24132570 DOI: 10.1007/S00401-013-1189-3 |
0.475 |
|
| 2013 |
Mackenzie IR, Arzberger T, Kremmer E, Troost D, Lorenzl S, Mori K, Weng SM, Haass C, Kretzschmar HA, Edbauer D, Neumann M. Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations. Acta Neuropathologica. 126: 859-79. PMID 24096617 DOI: 10.1007/S00401-013-1181-Y |
0.458 |
|
| 2013 |
Fleck D, van Bebber F, Colombo A, Galante C, Schwenk BM, Rabe L, Hampel H, Novak B, Kremmer E, Tahirovic S, Edbauer D, Lichtenthaler SF, Schmid B, Willem M, Haass C. Dual cleavage of neuregulin 1 type III by BACE1 and ADAM17 liberates its EGF-like domain and allows paracrine signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 7856-69. PMID 23637177 DOI: 10.1523/Jneurosci.3372-12.2013 |
0.444 |
|
| 2013 |
Schmid B, Hruscha A, Hogl S, Banzhaf-Strathmann J, Strecker K, van der Zee J, Teucke M, Eimer S, Hegermann J, Kittelmann M, Kremmer E, Cruts M, Solchenberger B, Hasenkamp L, van Bebber F, ... ... Edbauer D, et al. Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowth. Proceedings of the National Academy of Sciences of the United States of America. 110: 4986-91. PMID 23457265 DOI: 10.1073/Pnas.1218311110 |
0.459 |
|
| 2013 |
Mori K, Weng SM, Arzberger T, May S, Rentzsch K, Kremmer E, Schmid B, Kretzschmar HA, Cruts M, Van Broeckhoven C, Haass C, Edbauer D. The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS. Science (New York, N.Y.). 339: 1335-8. PMID 23393093 DOI: 10.1126/Science.1232927 |
0.476 |
|
| 2013 |
Mori K, Lammich S, Mackenzie IR, Forné I, Zilow S, Kretzschmar H, Edbauer D, Janssens J, Kleinberger G, Cruts M, Herms J, Neumann M, Van Broeckhoven C, Arzberger T, Haass C. hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients with C9orf72 mutations. Acta Neuropathologica. 125: 413-23. PMID 23381195 DOI: 10.1007/S00401-013-1088-7 |
0.475 |
|
| 2012 |
Orozco D, Tahirovic S, Rentzsch K, Schwenk BM, Haass C, Edbauer D. Loss of fused in sarcoma (FUS) promotes pathological Tau splicing. Embo Reports. 13: 759-64. PMID 22710833 DOI: 10.1038/Embor.2012.90 |
0.505 |
|
| 2012 |
Lang CM, Fellerer K, Schwenk BM, Kuhn PH, Kremmer E, Edbauer D, Capell A, Haass C. Membrane orientation and subcellular localization of transmembrane protein 106B (TMEM106B), a major risk factor for frontotemporal lobar degeneration. The Journal of Biological Chemistry. 287: 19355-65. PMID 22511793 DOI: 10.1074/Jbc.M112.365098 |
0.466 |
|
| 2010 |
Dormann D, Rodde R, Edbauer D, Bentmann E, Fischer I, Hruscha A, Than ME, Mackenzie IR, Capell A, Schmid B, Neumann M, Haass C. ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import. The Embo Journal. 29: 2841-57. PMID 20606625 DOI: 10.1038/Emboj.2010.143 |
0.453 |
|
| 2010 |
Foster KA, McLaughlin N, Edbauer D, Phillips M, Bolton A, Constantine-Paton M, Sheng M. Distinct roles of NR2A and NR2B cytoplasmic tails in long-term potentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2676-85. PMID 20164351 DOI: 10.1523/JNEUROSCI.4022-09.2010 |
0.449 |
|
| 2010 |
Edbauer D, Neilson JR, Foster KA, Wang CF, Seeburg DP, Batterton MN, Tada T, Dolan BM, Sharp PA, Sheng M. Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132. Neuron. 65: 373-84. PMID 20159450 DOI: 10.1016/J.Neuron.2010.01.005 |
0.432 |
|
| 2010 |
Haass C, Rodde R, Edbauer D, Bentmann E, Fischer I, Hruscha A, Than M, Mackenzie I, Capell A, Schmid B, Neumann M, Dormann D. O4-03-06: Familial Als-associated Fused in Sarcoma (fus) Mutations Disrupt Transportin-mediated Nuclear Import Alzheimer's & Dementia. 6: e17-e17. DOI: 10.1016/J.Jalz.2010.08.051 |
0.396 |
|
| 2009 |
Edbauer D, Cheng D, Batterton MN, Wang CF, Duong DM, Yaffe MB, Peng J, Sheng M. Identification and characterization of neuronal mitogen-activated protein kinase substrates using a specific phosphomotif antibody. Molecular & Cellular Proteomics : McP. 8: 681-95. PMID 19054758 DOI: 10.1074/Mcp.M800233-Mcp200 |
0.495 |
|
| 2007 |
Tada T, Simonetta A, Batterton M, Kinoshita M, Edbauer D, Sheng M. Role of Septin cytoskeleton in spine morphogenesis and dendrite development in neurons. Current Biology : Cb. 17: 1752-8. PMID 17935993 DOI: 10.1016/j.cub.2007.09.039 |
0.484 |
|
| 2004 |
Kaether C, Capell A, Edbauer D, Winkler E, Novak B, Steiner H, Haass C. The presenilin C-terminus is required for ER-retention, nicastrin-binding and gamma-secretase activity. The Embo Journal. 23: 4738-48. PMID 15549135 DOI: 10.1038/Sj.Emboj.7600478 |
0.526 |
|
| 2004 |
Shirotani K, Edbauer D, Prokop S, Haass C, Steiner H. Identification of distinct gamma-secretase complexes with different APH-1 variants. The Journal of Biological Chemistry. 279: 41340-5. PMID 15286082 DOI: 10.1074/Jbc.M405768200 |
0.673 |
|
| 2004 |
Edbauer D, Kaether C, Steiner H, Haass C. Co-expression of nicastrin and presenilin rescues a loss of function mutant of APH-1. The Journal of Biological Chemistry. 279: 37311-5. PMID 15210705 DOI: 10.1074/Jbc.M406228200 |
0.538 |
|
| 2004 |
Shirotani K, Edbauer D, Kostka M, Steiner H, Haass C. Immature nicastrin stabilizes APH-1 independent of PEN-2 and presenilin: identification of nicastrin mutants that selectively interact with APH-1. Journal of Neurochemistry. 89: 1520-7. PMID 15189355 DOI: 10.1111/J.1471-4159.2004.02447.X |
0.568 |
|
| 2004 |
Prokop S, Shirotani K, Edbauer D, Haass C, Steiner H. Requirement of PEN-2 for stabilization of the presenilin N-/C-terminal fragment heterodimer within the gamma-secretase complex. The Journal of Biological Chemistry. 279: 23255-61. PMID 15039426 DOI: 10.1074/Jbc.M401789200 |
0.7 |
|
| 2004 |
Steiner H, Prokop S, Shirotani K, Edbauer D, Winkler E, Haass C. P4-192 Structure-function analysis of the gamma-secretase complex subunit PEN-2 Neurobiology of Aging. 25: S530. DOI: 10.1016/S0197-4580(04)81750-0 |
0.647 |
|
| 2004 |
Hamid R, Willem M, Edbauer D, Steiner H, Müller U, Wünsch G, Kretzschmar H, Haass C, Herms J. O4-04-06 β-Amyloid precursor protein intracellular domain (AICD) strongly enhances resting free cytosolic calcium levels Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80277-X |
0.403 |
|
| 2003 |
Capell A, Kaether C, Edbauer D, Shirotani K, Merkl S, Steiner H, Haass C. Nicastrin interacts with gamma-secretase complex components via the N-terminal part of its transmembrane domain. The Journal of Biological Chemistry. 278: 52519-23. PMID 14602727 DOI: 10.1074/Jbc.C300435200 |
0.549 |
|
| 2003 |
Edbauer D, Winkler E, Regula JT, Pesold B, Steiner H, Haass C. Reconstitution of gamma-secretase activity. Nature Cell Biology. 5: 486-8. PMID 12679784 DOI: 10.1038/Ncb960 |
0.542 |
|
| 2003 |
Shirotani K, Edbauer D, Capell A, Schmitz J, Steiner H, Haass C. Gamma-secretase activity is associated with a conformational change of nicastrin. The Journal of Biological Chemistry. 278: 16474-7. PMID 12644462 DOI: 10.1074/Jbc.C300095200 |
0.544 |
|
| 2003 |
Steiner H, Edbauer D, Shirotani K, Haass C. S.03.03 Characterization and reconstitution of gamma-secretase European Neuropsychopharmacology. 13: S101. DOI: 10.1016/S0924-977X(03)91607-5 |
0.422 |
|
| 2002 |
Lammich S, Okochi M, Takeda M, Kaether C, Capell A, Zimmer AK, Edbauer D, Walter J, Steiner H, Haass C. Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Abeta-like peptide. The Journal of Biological Chemistry. 277: 44754-9. PMID 12223485 DOI: 10.1074/Jbc.M206872200 |
0.516 |
|
| 2002 |
Steiner H, Winkler E, Edbauer D, Prokop S, Basset G, Yamasaki A, Kostka M, Haass C. PEN-2 is an integral component of the gamma-secretase complex required for coordinated expression of presenilin and nicastrin. The Journal of Biological Chemistry. 277: 39062-5. PMID 12198112 DOI: 10.1074/Jbc.C200469200 |
0.698 |
|
| 2002 |
Kaether C, Lammich S, Edbauer D, Ertl M, Rietdorf J, Capell A, Steiner H, Haass C. Presenilin-1 affects trafficking and processing of betaAPP and is targeted in a complex with nicastrin to the plasma membrane. The Journal of Cell Biology. 158: 551-61. PMID 12147673 DOI: 10.1083/Jcb.200201123 |
0.526 |
|
| 2002 |
Edbauer D, Winkler E, Haass C, Steiner H. Presenilin and nicastrin regulate each other and determine amyloid beta-peptide production via complex formation. Proceedings of the National Academy of Sciences of the United States of America. 99: 8666-71. PMID 12048259 DOI: 10.1073/Pnas.132277899 |
0.564 |
|
| 2002 |
Moehlmann T, Winkler E, Xia X, Edbauer D, Murrell J, Capell A, Kaether C, Zheng H, Ghetti B, Haass C, Steiner H. Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Abeta 42 production. Proceedings of the National Academy of Sciences of the United States of America. 99: 8025-30. PMID 12048239 DOI: 10.1073/Pnas.112686799 |
0.519 |
|
| 2002 |
Edbauer D, Willem M, Lammich S, Steiner H, Haass C. Insulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD). The Journal of Biological Chemistry. 277: 13389-93. PMID 11809755 DOI: 10.1074/Jbc.M111571200 |
0.511 |
|
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